Amino acid dipepetide frequency for Phycicoccus elongatus Lp2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.576AlaAla: 19.576 ± 0.206	0.995AlaCys: 0.995 ± 0.034	8.243AlaAsp: 8.243 ± 0.108	7.027AlaGlu: 7.027 ± 0.097	3.444AlaPhe: 3.444 ± 0.06	11.919AlaGly: 11.919 ± 0.12	2.957AlaHis: 2.957 ± 0.059	5.231AlaIle: 5.231 ± 0.073	3.083AlaLys: 3.083 ± 0.076	14.084AlaLeu: 14.084 ± 0.161	3.0AlaMet: 3.0 ± 0.06	2.228AlaAsn: 2.228 ± 0.05	6.074AlaPro: 6.074 ± 0.087	3.758AlaGln: 3.758 ± 0.073	9.479AlaArg: 9.479 ± 0.116	6.43AlaSer: 6.43 ± 0.082	7.908AlaThr: 7.908 ± 0.114	11.004AlaVal: 11.004 ± 0.136	1.955AlaTrp: 1.955 ± 0.044	2.705AlaTyr: 2.705 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.919CysAla: 0.919 ± 0.029	0.103CysCys: 0.103 ± 0.01	0.442CysAsp: 0.442 ± 0.023	0.353CysGlu: 0.353 ± 0.021	0.223CysPhe: 0.223 ± 0.017	0.902CysGly: 0.902 ± 0.031	0.176CysHis: 0.176 ± 0.015	0.227CysIle: 0.227 ± 0.017	0.109CysLys: 0.109 ± 0.011	0.648CysLeu: 0.648 ± 0.027	0.122CysMet: 0.122 ± 0.012	0.104CysAsn: 0.104 ± 0.011	0.463CysPro: 0.463 ± 0.026	0.188CysGln: 0.188 ± 0.014	0.64CysArg: 0.64 ± 0.027	0.427CysSer: 0.427 ± 0.021	0.429CysThr: 0.429 ± 0.023	0.558CysVal: 0.558 ± 0.023	0.09CysTrp: 0.09 ± 0.01	0.12CysTyr: 0.12 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	7.487AspAla: 7.487 ± 0.094	0.373AspCys: 0.373 ± 0.023	4.183AspAsp: 4.183 ± 0.079	4.129AspGlu: 4.129 ± 0.074	1.636AspPhe: 1.636 ± 0.05	5.842AspGly: 5.842 ± 0.087	1.607AspHis: 1.607 ± 0.042	2.275AspIle: 2.275 ± 0.045	1.243AspLys: 1.243 ± 0.044	7.516AspLeu: 7.516 ± 0.092	0.883AspMet: 0.883 ± 0.03	1.089AspAsn: 1.089 ± 0.037	4.519AspPro: 4.519 ± 0.075	1.75AspGln: 1.75 ± 0.038	4.901AspArg: 4.901 ± 0.076	2.625AspSer: 2.625 ± 0.054	2.883AspThr: 2.883 ± 0.053	5.733AspVal: 5.733 ± 0.09	0.968AspTrp: 0.968 ± 0.037	1.126AspTyr: 1.126 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	6.984GluAla: 6.984 ± 0.098	0.312GluCys: 0.312 ± 0.018	2.905GluAsp: 2.905 ± 0.072	3.028GluGlu: 3.028 ± 0.069	1.586GluPhe: 1.586 ± 0.042	4.526GluGly: 4.526 ± 0.071	1.603GluHis: 1.603 ± 0.048	2.382GluIle: 2.382 ± 0.055	1.279GluLys: 1.279 ± 0.045	5.638GluLeu: 5.638 ± 0.068	0.944GluMet: 0.944 ± 0.032	0.892GluAsn: 0.892 ± 0.029	2.777GluPro: 2.777 ± 0.047	2.066GluGln: 2.066 ± 0.049	4.987GluArg: 4.987 ± 0.079	2.821GluSer: 2.821 ± 0.061	2.571GluThr: 2.571 ± 0.053	5.332GluVal: 5.332 ± 0.082	0.837GluTrp: 0.837 ± 0.033	0.793GluTyr: 0.793 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	3.608PheAla: 3.608 ± 0.071	0.239PheCys: 0.239 ± 0.015	2.066PheAsp: 2.066 ± 0.046	1.454PheGlu: 1.454 ± 0.042	0.966PhePhe: 0.966 ± 0.033	3.13PheGly: 3.13 ± 0.062	0.621PheHis: 0.621 ± 0.024	0.99PheIle: 0.99 ± 0.035	0.536PheLys: 0.536 ± 0.025	2.564PheLeu: 2.564 ± 0.059	0.446PheMet: 0.446 ± 0.022	0.6PheAsn: 0.6 ± 0.027	1.344PhePro: 1.344 ± 0.04	0.592PheGln: 0.592 ± 0.023	1.721PheArg: 1.721 ± 0.046	1.412PheSer: 1.412 ± 0.041	1.838PheThr: 1.838 ± 0.048	2.692PheVal: 2.692 ± 0.061	0.416PheTrp: 0.416 ± 0.021	0.541PheTyr: 0.541 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	10.278GlyAla: 10.278 ± 0.129	0.758GlyCys: 0.758 ± 0.029	5.191GlyAsp: 5.191 ± 0.079	4.986GlyGlu: 4.986 ± 0.077	2.938GlyPhe: 2.938 ± 0.061	7.846GlyGly: 7.846 ± 0.113	2.44GlyHis: 2.44 ± 0.05	4.123GlyIle: 4.123 ± 0.072	2.287GlyLys: 2.287 ± 0.051	9.652GlyLeu: 9.652 ± 0.118	2.11GlyMet: 2.11 ± 0.052	1.716GlyAsn: 1.716 ± 0.044	4.516GlyPro: 4.516 ± 0.082	2.861GlyGln: 2.861 ± 0.055	7.363GlyArg: 7.363 ± 0.099	5.361GlySer: 5.361 ± 0.068	5.49GlyThr: 5.49 ± 0.087	7.988GlyVal: 7.988 ± 0.103	1.742GlyTrp: 1.742 ± 0.052	1.989GlyTyr: 1.989 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	2.619HisAla: 2.619 ± 0.056	0.19HisCys: 0.19 ± 0.013	1.619HisAsp: 1.619 ± 0.041	1.366HisGlu: 1.366 ± 0.037	0.604HisPhe: 0.604 ± 0.028	2.278HisGly: 2.278 ± 0.047	0.703HisHis: 0.703 ± 0.029	0.652HisIle: 0.652 ± 0.028	0.382HisLys: 0.382 ± 0.021	2.649HisLeu: 2.649 ± 0.049	0.353HisMet: 0.353 ± 0.022	0.393HisAsn: 0.393 ± 0.025	1.741HisPro: 1.741 ± 0.052	0.671HisGln: 0.671 ± 0.026	2.11HisArg: 2.11 ± 0.049	1.076HisSer: 1.076 ± 0.038	1.257HisThr: 1.257 ± 0.035	2.111HisVal: 2.111 ± 0.045	0.365HisTrp: 0.365 ± 0.02	0.42HisTyr: 0.42 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	5.696IleAla: 5.696 ± 0.087	0.302IleCys: 0.302 ± 0.019	3.073IleAsp: 3.073 ± 0.064	2.532IleGlu: 2.532 ± 0.053	1.016IlePhe: 1.016 ± 0.04	4.263IleGly: 4.263 ± 0.066	0.8IleHis: 0.8 ± 0.027	1.41IleIle: 1.41 ± 0.046	0.88IleLys: 0.88 ± 0.036	3.239IleLeu: 3.239 ± 0.063	0.573IleMet: 0.573 ± 0.026	0.851IleAsn: 0.851 ± 0.033	2.238IlePro: 2.238 ± 0.051	0.827IleGln: 0.827 ± 0.026	2.532IleArg: 2.532 ± 0.056	1.997IleSer: 1.997 ± 0.05	2.466IleThr: 2.466 ± 0.056	3.925IleVal: 3.925 ± 0.068	0.498IleTrp: 0.498 ± 0.025	0.623IleTyr: 0.623 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	2.994LysAla: 2.994 ± 0.076	0.117LysCys: 0.117 ± 0.011	1.433LysAsp: 1.433 ± 0.048	1.184LysGlu: 1.184 ± 0.043	0.546LysPhe: 0.546 ± 0.028	2.006LysGly: 2.006 ± 0.055	0.422LysHis: 0.422 ± 0.02	0.847LysIle: 0.847 ± 0.038	0.808LysLys: 0.808 ± 0.031	1.649LysLeu: 1.649 ± 0.048	0.393LysMet: 0.393 ± 0.023	0.504LysAsn: 0.504 ± 0.027	1.161LysPro: 1.161 ± 0.036	0.618LysGln: 0.618 ± 0.028	1.567LysArg: 1.567 ± 0.046	1.149LysSer: 1.149 ± 0.038	1.243LysThr: 1.243 ± 0.042	2.252LysVal: 2.252 ± 0.056	0.288LysTrp: 0.288 ± 0.02	0.422LysTyr: 0.422 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	15.008LeuAla: 15.008 ± 0.18	0.668LeuCys: 0.668 ± 0.027	6.87LeuAsp: 6.87 ± 0.105	4.929LeuGlu: 4.929 ± 0.087	2.457LeuPhe: 2.457 ± 0.055	9.758LeuGly: 9.758 ± 0.126	2.093LeuHis: 2.093 ± 0.046	3.71LeuIle: 3.71 ± 0.075	1.975LeuLys: 1.975 ± 0.05	10.238LeuLeu: 10.238 ± 0.141	1.798LeuMet: 1.798 ± 0.052	1.58LeuAsn: 1.58 ± 0.049	5.626LeuPro: 5.626 ± 0.078	2.23LeuGln: 2.23 ± 0.045	7.789LeuArg: 7.789 ± 0.109	5.341LeuSer: 5.341 ± 0.076	6.809LeuThr: 6.809 ± 0.088	10.035LeuVal: 10.035 ± 0.13	1.376LeuTrp: 1.376 ± 0.053	1.344LeuTyr: 1.344 ± 0.036	0.0LeuXaa: 0.0 ± 0.0
Met	2.699MetAla: 2.699 ± 0.056	0.146MetCys: 0.146 ± 0.014	0.98MetAsp: 0.98 ± 0.032	0.815MetGlu: 0.815 ± 0.031	0.539MetPhe: 0.539 ± 0.025	1.6MetGly: 1.6 ± 0.04	0.383MetHis: 0.383 ± 0.019	0.795MetIle: 0.795 ± 0.029	0.473MetLys: 0.473 ± 0.023	1.764MetLeu: 1.764 ± 0.049	0.331MetMet: 0.331 ± 0.021	0.433MetAsn: 0.433 ± 0.02	1.312MetPro: 1.312 ± 0.035	0.46MetGln: 0.46 ± 0.022	1.557MetArg: 1.557 ± 0.048	1.548MetSer: 1.548 ± 0.044	1.857MetThr: 1.857 ± 0.042	1.558MetVal: 1.558 ± 0.04	0.229MetTrp: 0.229 ± 0.017	0.268MetTyr: 0.268 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.305AsnAla: 2.305 ± 0.058	0.166AsnCys: 0.166 ± 0.012	1.019AsnAsp: 1.019 ± 0.036	0.814AsnGlu: 0.814 ± 0.028	0.503AsnPhe: 0.503 ± 0.023	1.607AsnGly: 1.607 ± 0.048	0.395AsnHis: 0.395 ± 0.021	0.701AsnIle: 0.701 ± 0.031	0.393AsnLys: 0.393 ± 0.021	1.884AsnLeu: 1.884 ± 0.048	0.291AsnMet: 0.291 ± 0.018	0.415AsnAsn: 0.415 ± 0.024	1.503AsnPro: 1.503 ± 0.043	0.526AsnGln: 0.526 ± 0.025	1.225AsnArg: 1.225 ± 0.036	0.933AsnSer: 0.933 ± 0.033	1.048AsnThr: 1.048 ± 0.036	1.573AsnVal: 1.573 ± 0.043	0.315AsnTrp: 0.315 ± 0.018	0.424AsnTyr: 0.424 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	6.886ProAla: 6.886 ± 0.1	0.32ProCys: 0.32 ± 0.022	4.164ProAsp: 4.164 ± 0.067	3.646ProGlu: 3.646 ± 0.065	1.48ProPhe: 1.48 ± 0.037	5.627ProGly: 5.627 ± 0.088	1.322ProHis: 1.322 ± 0.037	2.111ProIle: 2.111 ± 0.052	1.17ProLys: 1.17 ± 0.035	4.781ProLeu: 4.781 ± 0.072	1.258ProMet: 1.258 ± 0.036	0.963ProAsn: 0.963 ± 0.037	2.829ProPro: 2.829 ± 0.072	1.502ProGln: 1.502 ± 0.039	3.84ProArg: 3.84 ± 0.065	3.404ProSer: 3.404 ± 0.071	3.944ProThr: 3.944 ± 0.062	4.993ProVal: 4.993 ± 0.071	0.995ProTrp: 0.995 ± 0.038	0.986ProTyr: 0.986 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	3.572GlnAla: 3.572 ± 0.064	0.19GlnCys: 0.19 ± 0.016	1.327GlnAsp: 1.327 ± 0.043	1.315GlnGlu: 1.315 ± 0.032	0.743GlnPhe: 0.743 ± 0.027	2.188GlnGly: 2.188 ± 0.052	0.675GlnHis: 0.675 ± 0.025	1.179GlnIle: 1.179 ± 0.04	0.572GlnLys: 0.572 ± 0.03	2.708GlnLeu: 2.708 ± 0.052	0.555GlnMet: 0.555 ± 0.027	0.456GlnAsn: 0.456 ± 0.025	1.573GlnPro: 1.573 ± 0.044	1.071GlnGln: 1.071 ± 0.038	2.538GlnArg: 2.538 ± 0.053	1.393GlnSer: 1.393 ± 0.039	1.4GlnThr: 1.4 ± 0.047	2.897GlnVal: 2.897 ± 0.051	0.606GlnTrp: 0.606 ± 0.029	0.426GlnTyr: 0.426 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	9.354ArgAla: 9.354 ± 0.125	0.55ArgCys: 0.55 ± 0.026	4.498ArgAsp: 4.498 ± 0.077	4.415ArgGlu: 4.415 ± 0.076	2.223ArgPhe: 2.223 ± 0.052	5.985ArgGly: 5.985 ± 0.081	2.116ArgHis: 2.116 ± 0.047	3.373ArgIle: 3.373 ± 0.062	1.485ArgLys: 1.485 ± 0.042	8.091ArgLeu: 8.091 ± 0.112	1.88ArgMet: 1.88 ± 0.044	1.264ArgAsn: 1.264 ± 0.039	4.508ArgPro: 4.508 ± 0.079	2.215ArgGln: 2.215 ± 0.054	7.369ArgArg: 7.369 ± 0.116	4.393ArgSer: 4.393 ± 0.074	4.437ArgThr: 4.437 ± 0.064	6.111ArgVal: 6.111 ± 0.084	1.418ArgTrp: 1.418 ± 0.037	1.411ArgTyr: 1.411 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	7.024SerAla: 7.024 ± 0.091	0.379SerCys: 0.379 ± 0.02	2.96SerAsp: 2.96 ± 0.058	2.444SerGlu: 2.444 ± 0.054	1.587SerPhe: 1.587 ± 0.043	5.686SerGly: 5.686 ± 0.08	1.099SerHis: 1.099 ± 0.03	2.064SerIle: 2.064 ± 0.046	1.036SerLys: 1.036 ± 0.037	4.946SerLeu: 4.946 ± 0.08	1.385SerMet: 1.385 ± 0.038	0.95SerAsn: 0.95 ± 0.034	3.313SerPro: 3.313 ± 0.063	1.37SerGln: 1.37 ± 0.039	3.988SerArg: 3.988 ± 0.071	3.241SerSer: 3.241 ± 0.067	3.603SerThr: 3.603 ± 0.063	4.575SerVal: 4.575 ± 0.076	0.927SerTrp: 0.927 ± 0.031	1.005SerTyr: 1.005 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	7.374ThrAla: 7.374 ± 0.096	0.459ThrCys: 0.459 ± 0.024	3.633ThrAsp: 3.633 ± 0.065	2.904ThrGlu: 2.904 ± 0.049	1.86ThrPhe: 1.86 ± 0.048	5.84ThrGly: 5.84 ± 0.088	1.389ThrHis: 1.389 ± 0.042	2.674ThrIle: 2.674 ± 0.051	1.425ThrLys: 1.425 ± 0.04	5.853ThrLeu: 5.853 ± 0.08	1.286ThrMet: 1.286 ± 0.037	1.229ThrAsn: 1.229 ± 0.036	4.06ThrPro: 4.06 ± 0.08	1.511ThrGln: 1.511 ± 0.042	4.119ThrArg: 4.119 ± 0.062	3.55ThrSer: 3.55 ± 0.059	4.326ThrThr: 4.326 ± 0.088	5.666ThrVal: 5.666 ± 0.076	1.052ThrTrp: 1.052 ± 0.034	1.253ThrTyr: 1.253 ± 0.043	0.0ThrXaa: 0.0 ± 0.0
Val	12.136ValAla: 12.136 ± 0.121	0.664ValCys: 0.664 ± 0.027	6.055ValAsp: 6.055 ± 0.089	5.271ValGlu: 5.271 ± 0.08	2.276ValPhe: 2.276 ± 0.055	7.848ValGly: 7.848 ± 0.111	2.045ValHis: 2.045 ± 0.045	3.874ValIle: 3.874 ± 0.07	1.831ValLys: 1.831 ± 0.047	9.887ValLeu: 9.887 ± 0.134	1.647ValMet: 1.647 ± 0.043	1.662ValAsn: 1.662 ± 0.046	4.941ValPro: 4.941 ± 0.075	2.121ValGln: 2.121 ± 0.047	6.651ValArg: 6.651 ± 0.086	4.597ValSer: 4.597 ± 0.06	6.166ValThr: 6.166 ± 0.091	9.596ValVal: 9.596 ± 0.144	1.081ValTrp: 1.081 ± 0.033	1.218ValTyr: 1.218 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.721TrpAla: 1.721 ± 0.049	0.165TrpCys: 0.165 ± 0.012	0.842TrpAsp: 0.842 ± 0.027	0.696TrpGlu: 0.696 ± 0.029	0.562TrpPhe: 0.562 ± 0.03	1.173TrpGly: 1.173 ± 0.041	0.354TrpHis: 0.354 ± 0.018	0.626TrpIle: 0.626 ± 0.029	0.263TrpLys: 0.263 ± 0.016	1.92TrpLeu: 1.92 ± 0.055	0.294TrpMet: 0.294 ± 0.016	0.363TrpAsn: 0.363 ± 0.022	0.836TrpPro: 0.836 ± 0.031	0.562TrpGln: 0.562 ± 0.029	1.326TrpArg: 1.326 ± 0.043	1.069TrpSer: 1.069 ± 0.033	0.967TrpThr: 0.967 ± 0.031	1.406TrpVal: 1.406 ± 0.048	0.434TrpTrp: 0.434 ± 0.024	0.279TrpTyr: 0.279 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.859TyrAla: 2.859 ± 0.053	0.147TyrCys: 0.147 ± 0.013	1.264TyrAsp: 1.264 ± 0.045	0.954TyrGlu: 0.954 ± 0.037	0.587TyrPhe: 0.587 ± 0.024	1.615TyrGly: 1.615 ± 0.041	0.356TyrHis: 0.356 ± 0.02	0.498TyrIle: 0.498 ± 0.023	0.372TyrLys: 0.372 ± 0.023	1.923TyrLeu: 1.923 ± 0.044	0.196TyrMet: 0.196 ± 0.016	0.35TyrAsn: 0.35 ± 0.022	0.888TyrPro: 0.888 ± 0.033	0.488TyrGln: 0.488 ± 0.024	1.393TyrArg: 1.393 ± 0.043	0.813TyrSer: 0.813 ± 0.03	0.821TyrThr: 0.821 ± 0.035	1.565TyrVal: 1.565 ± 0.046	0.265TyrTrp: 0.265 ± 0.017	0.383TyrTyr: 0.383 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3089 proteins (952598 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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