Amino acid dipepetide frequency for Rhizobium subbaraonis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.726AlaAla: 16.726 ± 0.14	1.034AlaCys: 1.034 ± 0.023	6.914AlaAsp: 6.914 ± 0.065	7.621AlaGlu: 7.621 ± 0.079	4.684AlaPhe: 4.684 ± 0.058	10.882AlaGly: 10.882 ± 0.082	2.134AlaHis: 2.134 ± 0.037	7.005AlaIle: 7.005 ± 0.066	3.961AlaLys: 3.961 ± 0.052	12.774AlaLeu: 12.774 ± 0.107	3.496AlaMet: 3.496 ± 0.054	2.992AlaAsn: 2.992 ± 0.038	4.963AlaPro: 4.963 ± 0.063	3.553AlaGln: 3.553 ± 0.049	8.414AlaArg: 8.414 ± 0.089	6.585AlaSer: 6.585 ± 0.064	6.111AlaThr: 6.111 ± 0.062	8.734AlaVal: 8.734 ± 0.082	1.46AlaTrp: 1.46 ± 0.035	2.638AlaTyr: 2.638 ± 0.034	0.0AlaXaa: 0.0 ± 0.0
Cys	0.899CysAla: 0.899 ± 0.024	0.125CysCys: 0.125 ± 0.008	0.503CysAsp: 0.503 ± 0.016	0.469CysGlu: 0.469 ± 0.014	0.305CysPhe: 0.305 ± 0.012	0.867CysGly: 0.867 ± 0.023	0.226CysHis: 0.226 ± 0.012	0.397CysIle: 0.397 ± 0.013	0.186CysLys: 0.186 ± 0.01	0.791CysLeu: 0.791 ± 0.022	0.163CysMet: 0.163 ± 0.009	0.207CysAsn: 0.207 ± 0.01	0.388CysPro: 0.388 ± 0.014	0.231CysGln: 0.231 ± 0.013	0.639CysArg: 0.639 ± 0.018	0.443CysSer: 0.443 ± 0.015	0.391CysThr: 0.391 ± 0.016	0.589CysVal: 0.589 ± 0.018	0.115CysTrp: 0.115 ± 0.007	0.206CysTyr: 0.206 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	6.704AspAla: 6.704 ± 0.065	0.475AspCys: 0.475 ± 0.016	3.285AspAsp: 3.285 ± 0.048	3.618AspGlu: 3.618 ± 0.05	2.292AspPhe: 2.292 ± 0.038	5.469AspGly: 5.469 ± 0.064	1.194AspHis: 1.194 ± 0.026	3.209AspIle: 3.209 ± 0.042	1.803AspLys: 1.803 ± 0.033	5.629AspLeu: 5.629 ± 0.055	1.393AspMet: 1.393 ± 0.024	1.427AspAsn: 1.427 ± 0.027	3.333AspPro: 3.333 ± 0.043	1.675AspGln: 1.675 ± 0.032	4.538AspArg: 4.538 ± 0.059	2.091AspSer: 2.091 ± 0.032	2.683AspThr: 2.683 ± 0.05	4.148AspVal: 4.148 ± 0.05	0.982AspTrp: 0.982 ± 0.024	1.48AspTyr: 1.48 ± 0.031	0.0AspXaa: 0.0 ± 0.0
Glu	7.729GluAla: 7.729 ± 0.075	0.374GluCys: 0.374 ± 0.015	2.854GluAsp: 2.854 ± 0.037	3.494GluGlu: 3.494 ± 0.06	1.796GluPhe: 1.796 ± 0.03	4.398GluGly: 4.398 ± 0.05	1.269GluHis: 1.269 ± 0.026	3.711GluIle: 3.711 ± 0.046	2.647GluLys: 2.647 ± 0.04	5.391GluLeu: 5.391 ± 0.061	1.576GluMet: 1.576 ± 0.032	1.819GluAsn: 1.819 ± 0.031	2.627GluPro: 2.627 ± 0.045	2.173GluGln: 2.173 ± 0.038	5.234GluArg: 5.234 ± 0.067	2.346GluSer: 2.346 ± 0.041	3.673GluThr: 3.673 ± 0.046	3.764GluVal: 3.764 ± 0.045	0.755GluTrp: 0.755 ± 0.023	1.039GluTyr: 1.039 ± 0.024	0.0GluXaa: 0.0 ± 0.0
Phe	4.64PheAla: 4.64 ± 0.048	0.404PheCys: 0.404 ± 0.016	2.721PheAsp: 2.721 ± 0.035	2.183PheGlu: 2.183 ± 0.031	1.501PhePhe: 1.501 ± 0.031	3.739PheGly: 3.739 ± 0.045	0.774PheHis: 0.774 ± 0.021	1.77PheIle: 1.77 ± 0.034	1.092PheLys: 1.092 ± 0.026	3.466PheLeu: 3.466 ± 0.046	0.872PheMet: 0.872 ± 0.021	1.1PheAsn: 1.1 ± 0.025	1.602PhePro: 1.602 ± 0.031	1.018PheGln: 1.018 ± 0.022	2.446PheArg: 2.446 ± 0.036	2.473PheSer: 2.473 ± 0.038	1.968PheThr: 1.968 ± 0.034	3.06PheVal: 3.06 ± 0.045	0.552PheTrp: 0.552 ± 0.02	0.921PheTyr: 0.921 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	8.928GlyAla: 8.928 ± 0.076	0.77GlyCys: 0.77 ± 0.023	4.433GlyAsp: 4.433 ± 0.053	5.059GlyGlu: 5.059 ± 0.059	3.569GlyPhe: 3.569 ± 0.047	7.342GlyGly: 7.342 ± 0.081	1.879GlyHis: 1.879 ± 0.032	4.919GlyIle: 4.919 ± 0.054	3.587GlyLys: 3.587 ± 0.049	8.601GlyLeu: 8.601 ± 0.079	2.345GlyMet: 2.345 ± 0.037	2.419GlyAsn: 2.419 ± 0.054	3.161GlyPro: 3.161 ± 0.043	2.748GlyGln: 2.748 ± 0.043	6.202GlyArg: 6.202 ± 0.061	4.818GlySer: 4.818 ± 0.049	4.659GlyThr: 4.659 ± 0.057	5.867GlyVal: 5.867 ± 0.055	1.286GlyTrp: 1.286 ± 0.031	2.383GlyTyr: 2.383 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	2.306HisAla: 2.306 ± 0.038	0.224HisCys: 0.224 ± 0.01	1.22HisAsp: 1.22 ± 0.03	1.045HisGlu: 1.045 ± 0.025	0.898HisPhe: 0.898 ± 0.024	1.928HisGly: 1.928 ± 0.033	0.567HisHis: 0.567 ± 0.019	0.954HisIle: 0.954 ± 0.02	0.489HisLys: 0.489 ± 0.017	2.024HisLeu: 2.024 ± 0.033	0.528HisMet: 0.528 ± 0.016	0.479HisAsn: 0.479 ± 0.015	1.259HisPro: 1.259 ± 0.031	0.577HisGln: 0.577 ± 0.016	1.479HisArg: 1.479 ± 0.032	0.95HisSer: 0.95 ± 0.026	0.777HisThr: 0.777 ± 0.019	1.511HisVal: 1.511 ± 0.029	0.316HisTrp: 0.316 ± 0.013	0.541HisTyr: 0.541 ± 0.017	0.0HisXaa: 0.0 ± 0.0
Ile	7.604IleAla: 7.604 ± 0.064	0.532IleCys: 0.532 ± 0.017	3.827IleAsp: 3.827 ± 0.049	3.742IleGlu: 3.742 ± 0.049	1.847IlePhe: 1.847 ± 0.035	5.151IleGly: 5.151 ± 0.061	0.952IleHis: 0.952 ± 0.023	2.397IleIle: 2.397 ± 0.036	1.461IleLys: 1.461 ± 0.03	4.691IleLeu: 4.691 ± 0.054	1.061IleMet: 1.061 ± 0.027	1.453IleAsn: 1.453 ± 0.029	2.359IlePro: 2.359 ± 0.038	1.252IleGln: 1.252 ± 0.027	3.574IleArg: 3.574 ± 0.047	3.106IleSer: 3.106 ± 0.036	2.69IleThr: 2.69 ± 0.039	4.582IleVal: 4.582 ± 0.056	0.646IleTrp: 0.646 ± 0.019	1.23IleTyr: 1.23 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	4.631LysAla: 4.631 ± 0.054	0.166LysCys: 0.166 ± 0.01	1.878LysAsp: 1.878 ± 0.032	1.833LysGlu: 1.833 ± 0.032	0.928LysPhe: 0.928 ± 0.024	2.74LysGly: 2.74 ± 0.042	0.625LysHis: 0.625 ± 0.018	1.844LysIle: 1.844 ± 0.035	1.4LysLys: 1.4 ± 0.033	3.417LysLeu: 3.417 ± 0.045	0.813LysMet: 0.813 ± 0.023	0.937LysAsn: 0.937 ± 0.022	2.043LysPro: 2.043 ± 0.034	1.073LysGln: 1.073 ± 0.026	2.48LysArg: 2.48 ± 0.037	1.964LysSer: 1.964 ± 0.033	2.097LysThr: 2.097 ± 0.033	2.594LysVal: 2.594 ± 0.038	0.378LysTrp: 0.378 ± 0.016	0.633LysTyr: 0.633 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	12.885LeuAla: 12.885 ± 0.099	0.855LeuCys: 0.855 ± 0.024	5.902LeuAsp: 5.902 ± 0.064	5.32LeuGlu: 5.32 ± 0.06	3.715LeuPhe: 3.715 ± 0.055	7.916LeuGly: 7.916 ± 0.077	1.77LeuHis: 1.77 ± 0.031	4.848LeuIle: 4.848 ± 0.062	3.823LeuLys: 3.823 ± 0.053	9.38LeuLeu: 9.38 ± 0.097	2.365LeuMet: 2.365 ± 0.034	2.538LeuAsn: 2.538 ± 0.038	5.283LeuPro: 5.283 ± 0.053	2.856LeuGln: 2.856 ± 0.04	6.336LeuArg: 6.336 ± 0.068	6.965LeuSer: 6.965 ± 0.071	5.393LeuThr: 5.393 ± 0.056	7.461LeuVal: 7.461 ± 0.07	1.098LeuTrp: 1.098 ± 0.026	2.101LeuTyr: 2.101 ± 0.04	0.0LeuXaa: 0.0 ± 0.0
Met	3.159MetAla: 3.159 ± 0.045	0.146MetCys: 0.146 ± 0.01	1.14MetAsp: 1.14 ± 0.025	1.26MetGlu: 1.26 ± 0.026	0.739MetPhe: 0.739 ± 0.021	1.697MetGly: 1.697 ± 0.031	0.411MetHis: 0.411 ± 0.017	1.429MetIle: 1.429 ± 0.03	1.103MetLys: 1.103 ± 0.024	2.6MetLeu: 2.6 ± 0.039	0.677MetMet: 0.677 ± 0.021	0.868MetAsn: 0.868 ± 0.02	1.453MetPro: 1.453 ± 0.029	0.872MetGln: 0.872 ± 0.024	1.864MetArg: 1.864 ± 0.031	1.736MetSer: 1.736 ± 0.03	1.95MetThr: 1.95 ± 0.033	1.71MetVal: 1.71 ± 0.032	0.202MetTrp: 0.202 ± 0.011	0.299MetTyr: 0.299 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.371AsnAla: 3.371 ± 0.042	0.234AsnCys: 0.234 ± 0.012	1.618AsnAsp: 1.618 ± 0.035	1.386AsnGlu: 1.386 ± 0.027	1.003AsnPhe: 1.003 ± 0.023	2.525AsnGly: 2.525 ± 0.041	0.532AsnHis: 0.532 ± 0.017	1.372AsnIle: 1.372 ± 0.027	0.719AsnLys: 0.719 ± 0.021	2.58AsnLeu: 2.58 ± 0.04	0.629AsnMet: 0.629 ± 0.019	0.739AsnAsn: 0.739 ± 0.024	1.808AsnPro: 1.808 ± 0.027	0.785AsnGln: 0.785 ± 0.02	1.961AsnArg: 1.961 ± 0.035	1.303AsnSer: 1.303 ± 0.026	1.277AsnThr: 1.277 ± 0.027	2.019AsnVal: 2.019 ± 0.033	0.455AsnTrp: 0.455 ± 0.017	0.69AsnTyr: 0.69 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	6.011ProAla: 6.011 ± 0.069	0.303ProCys: 0.303 ± 0.011	3.399ProAsp: 3.399 ± 0.046	3.62ProGlu: 3.62 ± 0.044	2.024ProPhe: 2.024 ± 0.032	4.123ProGly: 4.123 ± 0.05	1.024ProHis: 1.024 ± 0.022	2.3ProIle: 2.3 ± 0.038	1.666ProLys: 1.666 ± 0.032	4.435ProLeu: 4.435 ± 0.054	1.153ProMet: 1.153 ± 0.027	1.266ProAsn: 1.266 ± 0.027	2.304ProPro: 2.304 ± 0.042	1.624ProGln: 1.624 ± 0.028	2.692ProArg: 2.692 ± 0.039	2.768ProSer: 2.768 ± 0.038	2.339ProThr: 2.339 ± 0.036	4.15ProVal: 4.15 ± 0.052	0.649ProTrp: 0.649 ± 0.019	1.202ProTyr: 1.202 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	3.908GlnAla: 3.908 ± 0.048	0.195GlnCys: 0.195 ± 0.01	1.397GlnAsp: 1.397 ± 0.026	1.583GlnGlu: 1.583 ± 0.033	1.097GlnPhe: 1.097 ± 0.023	2.195GlnGly: 2.195 ± 0.036	0.628GlnHis: 0.628 ± 0.018	1.84GlnIle: 1.84 ± 0.034	1.213GlnLys: 1.213 ± 0.025	2.808GlnLeu: 2.808 ± 0.041	0.948GlnMet: 0.948 ± 0.023	0.851GlnAsn: 0.851 ± 0.023	1.723GlnPro: 1.723 ± 0.034	1.277GlnGln: 1.277 ± 0.03	2.34GlnArg: 2.34 ± 0.04	1.868GlnSer: 1.868 ± 0.034	1.735GlnThr: 1.735 ± 0.033	2.096GlnVal: 2.096 ± 0.035	0.41GlnTrp: 0.41 ± 0.015	0.595GlnTyr: 0.595 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	7.509ArgAla: 7.509 ± 0.063	0.474ArgCys: 0.474 ± 0.018	4.111ArgAsp: 4.111 ± 0.056	4.201ArgGlu: 4.201 ± 0.055	2.995ArgPhe: 2.995 ± 0.044	4.576ArgGly: 4.576 ± 0.053	1.812ArgHis: 1.812 ± 0.032	4.113ArgIle: 4.113 ± 0.048	2.67ArgLys: 2.67 ± 0.037	7.744ArgLeu: 7.744 ± 0.079	1.985ArgMet: 1.985 ± 0.035	2.031ArgAsn: 2.031 ± 0.033	3.501ArgPro: 3.501 ± 0.049	2.762ArgGln: 2.762 ± 0.041	5.819ArgArg: 5.819 ± 0.079	3.979ArgSer: 3.979 ± 0.049	3.543ArgThr: 3.543 ± 0.048	4.459ArgVal: 4.459 ± 0.051	0.949ArgTrp: 0.949 ± 0.024	1.778ArgTyr: 1.778 ± 0.032	0.0ArgXaa: 0.0 ± 0.0
Ser	6.569SerAla: 6.569 ± 0.067	0.419SerCys: 0.419 ± 0.015	3.216SerAsp: 3.216 ± 0.044	3.108SerGlu: 3.108 ± 0.047	2.429SerPhe: 2.429 ± 0.035	5.825SerGly: 5.825 ± 0.059	1.149SerHis: 1.149 ± 0.021	3.075SerIle: 3.075 ± 0.048	1.67SerLys: 1.67 ± 0.033	5.55SerLeu: 5.55 ± 0.054	1.406SerMet: 1.406 ± 0.028	1.462SerAsn: 1.462 ± 0.027	2.774SerPro: 2.774 ± 0.043	1.651SerGln: 1.651 ± 0.029	3.825SerArg: 3.825 ± 0.05	3.187SerSer: 3.187 ± 0.043	2.845SerThr: 2.845 ± 0.043	4.175SerVal: 4.175 ± 0.048	0.726SerTrp: 0.726 ± 0.016	1.309SerTyr: 1.309 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	6.337ThrAla: 6.337 ± 0.058	0.403ThrCys: 0.403 ± 0.016	2.837ThrAsp: 2.837 ± 0.042	2.725ThrGlu: 2.725 ± 0.04	2.14ThrPhe: 2.14 ± 0.031	5.173ThrGly: 5.173 ± 0.055	0.965ThrHis: 0.965 ± 0.026	3.253ThrIle: 3.253 ± 0.046	1.523ThrLys: 1.523 ± 0.031	5.659ThrLeu: 5.659 ± 0.059	1.288ThrMet: 1.288 ± 0.025	1.316ThrAsn: 1.316 ± 0.023	2.969ThrPro: 2.969 ± 0.041	1.355ThrGln: 1.355 ± 0.029	3.234ThrArg: 3.234 ± 0.042	2.882ThrSer: 2.882 ± 0.039	2.791ThrThr: 2.791 ± 0.044	4.491ThrVal: 4.491 ± 0.046	0.616ThrTrp: 0.616 ± 0.018	1.243ThrTyr: 1.243 ± 0.027	0.0ThrXaa: 0.0 ± 0.0
Val	9.117ValAla: 9.117 ± 0.081	0.62ValCys: 0.62 ± 0.019	4.076ValAsp: 4.076 ± 0.053	4.547ValGlu: 4.547 ± 0.05	2.867ValPhe: 2.867 ± 0.037	5.435ValGly: 5.435 ± 0.068	1.371ValHis: 1.371 ± 0.026	4.077ValIle: 4.077 ± 0.042	2.344ValLys: 2.344 ± 0.037	7.31ValLeu: 7.31 ± 0.062	1.816ValMet: 1.816 ± 0.034	2.003ValAsn: 2.003 ± 0.033	3.728ValPro: 3.728 ± 0.047	1.93ValGln: 1.93 ± 0.036	4.979ValArg: 4.979 ± 0.054	4.789ValSer: 4.789 ± 0.053	4.474ValThr: 4.474 ± 0.056	6.015ValVal: 6.015 ± 0.075	0.861ValTrp: 0.861 ± 0.021	1.528ValTyr: 1.528 ± 0.028	0.0ValXaa: 0.0 ± 0.0
Trp	1.166TrpAla: 1.166 ± 0.024	0.143TrpCys: 0.143 ± 0.009	0.631TrpAsp: 0.631 ± 0.021	0.566TrpGlu: 0.566 ± 0.016	0.52TrpPhe: 0.52 ± 0.016	0.828TrpGly: 0.828 ± 0.025	0.297TrpHis: 0.297 ± 0.013	0.706TrpIle: 0.706 ± 0.02	0.511TrpLys: 0.511 ± 0.015	1.623TrpLeu: 1.623 ± 0.031	0.337TrpMet: 0.337 ± 0.013	0.489TrpAsn: 0.489 ± 0.015	0.685TrpPro: 0.685 ± 0.02	0.581TrpGln: 0.581 ± 0.018	1.078TrpArg: 1.078 ± 0.025	0.86TrpSer: 0.86 ± 0.021	0.753TrpThr: 0.753 ± 0.022	0.737TrpVal: 0.737 ± 0.019	0.225TrpTrp: 0.225 ± 0.011	0.289TrpTyr: 0.289 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.484TyrAla: 2.484 ± 0.031	0.242TyrCys: 0.242 ± 0.011	1.468TyrAsp: 1.468 ± 0.032	1.288TyrGlu: 1.288 ± 0.026	0.95TyrPhe: 0.95 ± 0.023	2.164TyrGly: 2.164 ± 0.035	0.491TyrHis: 0.491 ± 0.017	0.939TyrIle: 0.939 ± 0.021	0.605TyrLys: 0.605 ± 0.017	2.339TyrLeu: 2.339 ± 0.034	0.466TyrMet: 0.466 ± 0.017	0.607TyrAsn: 0.607 ± 0.021	1.086TyrPro: 1.086 ± 0.024	0.712TyrGln: 0.712 ± 0.02	1.879TyrArg: 1.879 ± 0.032	1.26TyrSer: 1.26 ± 0.029	1.052TyrThr: 1.052 ± 0.023	1.723TyrVal: 1.723 ± 0.033	0.344TyrTrp: 0.344 ± 0.013	0.623TyrTyr: 0.623 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6271 proteins (1918300 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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