Amino acid dipepetide frequency for Luteimonas cucumeris

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.827AlaAla: 17.827 ± 0.199	1.169AlaCys: 1.169 ± 0.035	7.391AlaAsp: 7.391 ± 0.096	6.884AlaGlu: 6.884 ± 0.102	4.195AlaPhe: 4.195 ± 0.082	11.015AlaGly: 11.015 ± 0.128	2.623AlaHis: 2.623 ± 0.051	6.146AlaIle: 6.146 ± 0.097	3.513AlaLys: 3.513 ± 0.078	15.232AlaLeu: 15.232 ± 0.161	3.53AlaMet: 3.53 ± 0.069	3.054AlaAsn: 3.054 ± 0.07	5.911AlaPro: 5.911 ± 0.105	5.47AlaGln: 5.47 ± 0.08	9.747AlaArg: 9.747 ± 0.124	6.862AlaSer: 6.862 ± 0.105	6.779AlaThr: 6.779 ± 0.104	8.641AlaVal: 8.641 ± 0.126	2.002AlaTrp: 2.002 ± 0.049	2.62AlaTyr: 2.62 ± 0.057	0.0AlaXaa: 0.0 ± 0.0
Cys	0.972CysAla: 0.972 ± 0.027	0.108CysCys: 0.108 ± 0.01	0.505CysAsp: 0.505 ± 0.02	0.433CysGlu: 0.433 ± 0.021	0.267CysPhe: 0.267 ± 0.016	0.879CysGly: 0.879 ± 0.032	0.221CysHis: 0.221 ± 0.015	0.301CysIle: 0.301 ± 0.017	0.163CysLys: 0.163 ± 0.014	0.784CysLeu: 0.784 ± 0.029	0.14CysMet: 0.14 ± 0.011	0.217CysAsn: 0.217 ± 0.015	0.372CysPro: 0.372 ± 0.02	0.216CysGln: 0.216 ± 0.017	0.604CysArg: 0.604 ± 0.027	0.44CysSer: 0.44 ± 0.021	0.408CysThr: 0.408 ± 0.021	0.688CysVal: 0.688 ± 0.027	0.124CysTrp: 0.124 ± 0.011	0.172CysTyr: 0.172 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	9.05AspAla: 9.05 ± 0.119	0.457AspCys: 0.457 ± 0.019	3.99AspAsp: 3.99 ± 0.071	3.534AspGlu: 3.534 ± 0.062	2.187AspPhe: 2.187 ± 0.049	6.225AspGly: 6.225 ± 0.091	1.214AspHis: 1.214 ± 0.032	2.52AspIle: 2.52 ± 0.052	1.737AspLys: 1.737 ± 0.045	5.54AspLeu: 5.54 ± 0.072	1.153AspMet: 1.153 ± 0.036	1.485AspAsn: 1.485 ± 0.045	3.531AspPro: 3.531 ± 0.064	1.643AspGln: 1.643 ± 0.042	4.236AspArg: 4.236 ± 0.062	2.815AspSer: 2.815 ± 0.055	2.915AspThr: 2.915 ± 0.049	4.206AspVal: 4.206 ± 0.072	1.104AspTrp: 1.104 ± 0.031	1.7AspTyr: 1.7 ± 0.048	0.0AspXaa: 0.0 ± 0.0
Glu	6.885GluAla: 6.885 ± 0.105	0.329GluCys: 0.329 ± 0.02	2.42GluAsp: 2.42 ± 0.054	2.336GluGlu: 2.336 ± 0.053	1.782GluPhe: 1.782 ± 0.052	3.759GluGly: 3.759 ± 0.061	1.401GluHis: 1.401 ± 0.039	2.545GluIle: 2.545 ± 0.051	1.599GluLys: 1.599 ± 0.042	6.01GluLeu: 6.01 ± 0.073	1.153GluMet: 1.153 ± 0.035	1.332GluAsn: 1.332 ± 0.037	2.535GluPro: 2.535 ± 0.05	2.644GluGln: 2.644 ± 0.056	5.112GluArg: 5.112 ± 0.082	2.701GluSer: 2.701 ± 0.054	2.731GluThr: 2.731 ± 0.049	3.818GluVal: 3.818 ± 0.063	0.718GluTrp: 0.718 ± 0.024	1.241GluTyr: 1.241 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	4.514PheAla: 4.514 ± 0.076	0.32PheCys: 0.32 ± 0.016	2.757PheAsp: 2.757 ± 0.053	1.997PheGlu: 1.997 ± 0.049	1.155PhePhe: 1.155 ± 0.034	3.525PheGly: 3.525 ± 0.065	0.751PheHis: 0.751 ± 0.025	1.286PheIle: 1.286 ± 0.036	0.883PheLys: 0.883 ± 0.033	2.915PheLeu: 2.915 ± 0.06	0.669PheMet: 0.669 ± 0.028	1.055PheAsn: 1.055 ± 0.032	1.398PhePro: 1.398 ± 0.037	0.934PheGln: 0.934 ± 0.034	2.19PheArg: 2.19 ± 0.05	1.936PheSer: 1.936 ± 0.05	1.637PheThr: 1.637 ± 0.042	2.658PheVal: 2.658 ± 0.055	0.535PheTrp: 0.535 ± 0.026	0.791PheTyr: 0.791 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	9.147GlyAla: 9.147 ± 0.134	0.752GlyCys: 0.752 ± 0.029	5.262GlyAsp: 5.262 ± 0.098	4.873GlyGlu: 4.873 ± 0.07	3.476GlyPhe: 3.476 ± 0.061	7.123GlyGly: 7.123 ± 0.112	2.037GlyHis: 2.037 ± 0.051	4.225GlyIle: 4.225 ± 0.072	3.15GlyLys: 3.15 ± 0.066	8.524GlyLeu: 8.524 ± 0.105	2.194GlyMet: 2.194 ± 0.046	2.724GlyAsn: 2.724 ± 0.068	2.903GlyPro: 2.903 ± 0.057	3.068GlyGln: 3.068 ± 0.062	6.125GlyArg: 6.125 ± 0.083	5.005GlySer: 5.005 ± 0.106	4.404GlyThr: 4.404 ± 0.096	6.379GlyVal: 6.379 ± 0.095	1.641GlyTrp: 1.641 ± 0.038	2.493GlyTyr: 2.493 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	3.243HisAla: 3.243 ± 0.066	0.252HisCys: 0.252 ± 0.015	1.478HisAsp: 1.478 ± 0.047	1.172HisGlu: 1.172 ± 0.035	0.817HisPhe: 0.817 ± 0.028	2.359HisGly: 2.359 ± 0.05	0.591HisHis: 0.591 ± 0.026	0.731HisIle: 0.731 ± 0.028	0.473HisLys: 0.473 ± 0.019	2.118HisLeu: 2.118 ± 0.048	0.411HisMet: 0.411 ± 0.02	0.47HisAsn: 0.47 ± 0.024	1.392HisPro: 1.392 ± 0.034	0.598HisGln: 0.598 ± 0.024	1.732HisArg: 1.732 ± 0.042	0.938HisSer: 0.938 ± 0.031	0.891HisThr: 0.891 ± 0.029	1.607HisVal: 1.607 ± 0.041	0.42HisTrp: 0.42 ± 0.02	0.615HisTyr: 0.615 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	7.113IleAla: 7.113 ± 0.095	0.36IleCys: 0.36 ± 0.016	3.742IleAsp: 3.742 ± 0.054	3.202IleGlu: 3.202 ± 0.049	1.137IlePhe: 1.137 ± 0.043	4.623IleGly: 4.623 ± 0.076	0.818IleHis: 0.818 ± 0.027	1.341IleIle: 1.341 ± 0.044	1.071IleLys: 1.071 ± 0.041	3.011IleLeu: 3.011 ± 0.063	0.518IleMet: 0.518 ± 0.023	1.254IleAsn: 1.254 ± 0.038	2.001IlePro: 2.001 ± 0.053	1.045IleGln: 1.045 ± 0.035	2.884IleArg: 2.884 ± 0.051	2.145IleSer: 2.145 ± 0.053	2.141IleThr: 2.141 ± 0.056	3.587IleVal: 3.587 ± 0.062	0.433IleTrp: 0.433 ± 0.024	0.816IleTyr: 0.816 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	3.482LysAla: 3.482 ± 0.077	0.128LysCys: 0.128 ± 0.013	1.489LysAsp: 1.489 ± 0.04	1.164LysGlu: 1.164 ± 0.039	0.765LysPhe: 0.765 ± 0.026	1.994LysGly: 1.994 ± 0.045	0.622LysHis: 0.622 ± 0.024	1.181LysIle: 1.181 ± 0.037	1.017LysLys: 1.017 ± 0.056	3.138LysLeu: 3.138 ± 0.052	0.645LysMet: 0.645 ± 0.025	0.693LysAsn: 0.693 ± 0.028	2.082LysPro: 2.082 ± 0.052	1.263LysGln: 1.263 ± 0.041	2.159LysArg: 2.159 ± 0.047	1.471LysSer: 1.471 ± 0.035	1.58LysThr: 1.58 ± 0.046	2.098LysVal: 2.098 ± 0.051	0.305LysTrp: 0.305 ± 0.018	0.682LysTyr: 0.682 ± 0.027	0.0LysXaa: 0.0 ± 0.0
Leu	14.69LeuAla: 14.69 ± 0.161	0.953LeuCys: 0.953 ± 0.03	6.808LeuAsp: 6.808 ± 0.089	5.062LeuGlu: 5.062 ± 0.082	3.427LeuPhe: 3.427 ± 0.058	8.514LeuGly: 8.514 ± 0.098	2.489LeuHis: 2.489 ± 0.052	3.941LeuIle: 3.941 ± 0.074	3.042LeuLys: 3.042 ± 0.056	11.935LeuLeu: 11.935 ± 0.137	2.132LeuMet: 2.132 ± 0.046	2.254LeuAsn: 2.254 ± 0.051	6.323LeuPro: 6.323 ± 0.092	4.286LeuGln: 4.286 ± 0.072	8.686LeuArg: 8.686 ± 0.126	6.029LeuSer: 6.029 ± 0.079	4.578LeuThr: 4.578 ± 0.07	7.476LeuVal: 7.476 ± 0.1	1.356LeuTrp: 1.356 ± 0.041	2.177LeuTyr: 2.177 ± 0.046	0.0LeuXaa: 0.0 ± 0.0
Met	2.742MetAla: 2.742 ± 0.056	0.129MetCys: 0.129 ± 0.011	1.063MetAsp: 1.063 ± 0.03	0.89MetGlu: 0.89 ± 0.032	0.619MetPhe: 0.619 ± 0.024	1.48MetGly: 1.48 ± 0.038	0.492MetHis: 0.492 ± 0.024	0.929MetIle: 0.929 ± 0.028	0.893MetLys: 0.893 ± 0.028	2.515MetLeu: 2.515 ± 0.057	0.468MetMet: 0.468 ± 0.023	0.731MetAsn: 0.731 ± 0.026	1.441MetPro: 1.441 ± 0.034	0.953MetGln: 0.953 ± 0.031	1.801MetArg: 1.801 ± 0.044	1.542MetSer: 1.542 ± 0.043	1.44MetThr: 1.44 ± 0.036	1.368MetVal: 1.368 ± 0.039	0.193MetTrp: 0.193 ± 0.013	0.382MetTyr: 0.382 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.511AsnAla: 3.511 ± 0.078	0.215AsnCys: 0.215 ± 0.016	1.571AsnAsp: 1.571 ± 0.042	1.291AsnGlu: 1.291 ± 0.037	0.845AsnPhe: 0.845 ± 0.028	2.339AsnGly: 2.339 ± 0.062	0.51AsnHis: 0.51 ± 0.022	1.089AsnIle: 1.089 ± 0.037	0.63AsnLys: 0.63 ± 0.028	2.478AsnLeu: 2.478 ± 0.053	0.451AsnMet: 0.451 ± 0.024	0.681AsnAsn: 0.681 ± 0.036	1.679AsnPro: 1.679 ± 0.045	0.789AsnGln: 0.789 ± 0.027	1.809AsnArg: 1.809 ± 0.043	1.277AsnSer: 1.277 ± 0.052	1.396AsnThr: 1.396 ± 0.048	1.942AsnVal: 1.942 ± 0.054	0.379AsnTrp: 0.379 ± 0.022	0.659AsnTyr: 0.659 ± 0.026	0.0AsnXaa: 0.0 ± 0.0
Pro	6.951ProAla: 6.951 ± 0.103	0.315ProCys: 0.315 ± 0.018	3.547ProAsp: 3.547 ± 0.065	3.232ProGlu: 3.232 ± 0.067	1.595ProPhe: 1.595 ± 0.043	4.665ProGly: 4.665 ± 0.079	1.039ProHis: 1.039 ± 0.032	1.993ProIle: 1.993 ± 0.04	1.355ProLys: 1.355 ± 0.044	5.225ProLeu: 5.225 ± 0.079	1.318ProMet: 1.318 ± 0.039	1.173ProAsn: 1.173 ± 0.042	2.834ProPro: 2.834 ± 0.067	2.228ProGln: 2.228 ± 0.049	3.509ProArg: 3.509 ± 0.063	2.636ProSer: 2.636 ± 0.053	2.466ProThr: 2.466 ± 0.048	4.054ProVal: 4.054 ± 0.065	0.833ProTrp: 0.833 ± 0.032	1.171ProTyr: 1.171 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	5.442GlnAla: 5.442 ± 0.096	0.24GlnCys: 0.24 ± 0.016	1.665GlnAsp: 1.665 ± 0.039	1.417GlnGlu: 1.417 ± 0.038	1.199GlnPhe: 1.199 ± 0.034	2.788GlnGly: 2.788 ± 0.053	0.899GlnHis: 0.899 ± 0.03	1.526GlnIle: 1.526 ± 0.046	0.981GlnLys: 0.981 ± 0.032	4.2GlnLeu: 4.2 ± 0.074	0.867GlnMet: 0.867 ± 0.028	0.764GlnAsn: 0.764 ± 0.032	2.305GlnPro: 2.305 ± 0.055	1.954GlnGln: 1.954 ± 0.049	3.759GlnArg: 3.759 ± 0.068	1.865GlnSer: 1.865 ± 0.049	1.614GlnThr: 1.614 ± 0.04	2.957GlnVal: 2.957 ± 0.056	0.623GlnTrp: 0.623 ± 0.027	0.797GlnTyr: 0.797 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	8.408ArgAla: 8.408 ± 0.115	0.561ArgCys: 0.561 ± 0.026	5.039ArgAsp: 5.039 ± 0.071	4.844ArgGlu: 4.844 ± 0.072	2.943ArgPhe: 2.943 ± 0.052	5.531ArgGly: 5.531 ± 0.076	1.96ArgHis: 1.96 ± 0.039	4.251ArgIle: 4.251 ± 0.067	2.181ArgLys: 2.181 ± 0.052	8.289ArgLeu: 8.289 ± 0.108	1.966ArgMet: 1.966 ± 0.043	2.127ArgAsn: 2.127 ± 0.04	3.364ArgPro: 3.364 ± 0.064	3.05ArgGln: 3.05 ± 0.068	6.123ArgArg: 6.123 ± 0.087	3.851ArgSer: 3.851 ± 0.056	3.364ArgThr: 3.364 ± 0.057	5.214ArgVal: 5.214 ± 0.078	1.422ArgTrp: 1.422 ± 0.041	2.295ArgTyr: 2.295 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	6.454SerAla: 6.454 ± 0.093	0.404SerCys: 0.404 ± 0.021	3.038SerAsp: 3.038 ± 0.053	2.643SerGlu: 2.643 ± 0.046	1.879SerPhe: 1.879 ± 0.053	5.45SerGly: 5.45 ± 0.098	1.175SerHis: 1.175 ± 0.027	2.29SerIle: 2.29 ± 0.061	1.466SerLys: 1.466 ± 0.041	5.378SerLeu: 5.378 ± 0.081	1.096SerMet: 1.096 ± 0.034	1.465SerAsn: 1.465 ± 0.053	2.835SerPro: 2.835 ± 0.058	1.904SerGln: 1.904 ± 0.046	3.898SerArg: 3.898 ± 0.062	3.099SerSer: 3.099 ± 0.065	2.854SerThr: 2.854 ± 0.062	3.67SerVal: 3.67 ± 0.08	0.806SerTrp: 0.806 ± 0.03	1.348SerTyr: 1.348 ± 0.044	0.0SerXaa: 0.0 ± 0.0
Thr	6.094ThrAla: 6.094 ± 0.106	0.392ThrCys: 0.392 ± 0.021	2.664ThrAsp: 2.664 ± 0.051	2.129ThrGlu: 2.129 ± 0.045	1.547ThrPhe: 1.547 ± 0.041	4.524ThrGly: 4.524 ± 0.074	1.114ThrHis: 1.114 ± 0.033	2.105ThrIle: 2.105 ± 0.055	0.95ThrLys: 0.95 ± 0.034	6.088ThrLeu: 6.088 ± 0.082	1.012ThrMet: 1.012 ± 0.036	1.063ThrAsn: 1.063 ± 0.043	3.496ThrPro: 3.496 ± 0.071	1.76ThrGln: 1.76 ± 0.044	3.622ThrArg: 3.622 ± 0.06	2.424ThrSer: 2.424 ± 0.052	2.669ThrThr: 2.669 ± 0.061	3.8ThrVal: 3.8 ± 0.069	0.656ThrTrp: 0.656 ± 0.023	1.1ThrTyr: 1.1 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	9.796ValAla: 9.796 ± 0.116	0.6ValCys: 0.6 ± 0.023	4.641ValAsp: 4.641 ± 0.068	4.202ValGlu: 4.202 ± 0.061	2.574ValPhe: 2.574 ± 0.055	5.578ValGly: 5.578 ± 0.093	1.512ValHis: 1.512 ± 0.042	3.351ValIle: 3.351 ± 0.068	1.842ValLys: 1.842 ± 0.047	8.0ValLeu: 8.0 ± 0.102	1.541ValMet: 1.541 ± 0.041	1.87ValAsn: 1.87 ± 0.049	3.755ValPro: 3.755 ± 0.063	2.434ValGln: 2.434 ± 0.058	5.239ValArg: 5.239 ± 0.077	4.032ValSer: 4.032 ± 0.071	3.449ValThr: 3.449 ± 0.066	5.833ValVal: 5.833 ± 0.091	0.877ValTrp: 0.877 ± 0.032	1.472ValTyr: 1.472 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	1.275TrpAla: 1.275 ± 0.04	0.136TrpCys: 0.136 ± 0.011	0.69TrpAsp: 0.69 ± 0.028	0.547TrpGlu: 0.547 ± 0.024	0.593TrpPhe: 0.593 ± 0.026	0.91TrpGly: 0.91 ± 0.033	0.363TrpHis: 0.363 ± 0.017	0.734TrpIle: 0.734 ± 0.032	0.467TrpLys: 0.467 ± 0.024	2.299TrpLeu: 2.299 ± 0.057	0.422TrpMet: 0.422 ± 0.021	0.502TrpAsn: 0.502 ± 0.022	0.821TrpPro: 0.821 ± 0.031	0.792TrpGln: 0.792 ± 0.026	1.424TrpArg: 1.424 ± 0.038	0.897TrpSer: 0.897 ± 0.03	0.724TrpThr: 0.724 ± 0.028	0.904TrpVal: 0.904 ± 0.031	0.333TrpTrp: 0.333 ± 0.02	0.326TrpTyr: 0.326 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.017TyrAla: 3.017 ± 0.066	0.192TyrCys: 0.192 ± 0.013	1.484TyrAsp: 1.484 ± 0.041	1.2TyrGlu: 1.2 ± 0.034	0.904TyrPhe: 0.904 ± 0.034	2.221TyrGly: 2.221 ± 0.056	0.48TyrHis: 0.48 ± 0.021	0.756TyrIle: 0.756 ± 0.027	0.544TyrLys: 0.544 ± 0.028	2.479TyrLeu: 2.479 ± 0.051	0.386TyrMet: 0.386 ± 0.019	0.627TyrAsn: 0.627 ± 0.028	1.159TyrPro: 1.159 ± 0.036	0.83TyrGln: 0.83 ± 0.029	2.124TyrArg: 2.124 ± 0.049	1.189TyrSer: 1.189 ± 0.042	1.168TyrThr: 1.168 ± 0.043	1.698TyrVal: 1.698 ± 0.041	0.398TyrTrp: 0.398 ± 0.019	0.631TyrTyr: 0.631 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3213 proteins (1045802 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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