Amino acid dipepetide frequency for Diaphorina citri (Asian citrus psyllid)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.931AlaAla: 3.931 ± 0.039	1.073AlaCys: 1.073 ± 0.022	2.734AlaAsp: 2.734 ± 0.023	3.34AlaGlu: 3.34 ± 0.028	1.986AlaPhe: 1.986 ± 0.019	2.949AlaGly: 2.949 ± 0.024	1.312AlaHis: 1.312 ± 0.015	2.834AlaIle: 2.834 ± 0.023	3.653AlaLys: 3.653 ± 0.032	5.028AlaLeu: 5.028 ± 0.038	1.335AlaMet: 1.335 ± 0.014	2.511AlaAsn: 2.511 ± 0.02	2.968AlaPro: 2.968 ± 0.038	2.291AlaGln: 2.291 ± 0.02	2.733AlaArg: 2.733 ± 0.021	4.589AlaSer: 4.589 ± 0.038	3.271AlaThr: 3.271 ± 0.024	3.382AlaVal: 3.382 ± 0.03	0.541AlaTrp: 0.541 ± 0.01	1.658AlaTyr: 1.658 ± 0.024	0.001AlaXaa: 0.001 ± 0.0
Cys	1.007CysAla: 1.007 ± 0.017	0.477CysCys: 0.477 ± 0.011	1.197CysAsp: 1.197 ± 0.02	1.149CysGlu: 1.149 ± 0.019	0.794CysPhe: 0.794 ± 0.011	1.24CysGly: 1.24 ± 0.023	0.546CysHis: 0.546 ± 0.011	1.101CysIle: 1.101 ± 0.018	1.276CysLys: 1.276 ± 0.019	1.846CysLeu: 1.846 ± 0.022	0.415CysMet: 0.415 ± 0.008	1.01CysAsn: 1.01 ± 0.015	1.093CysPro: 1.093 ± 0.031	0.766CysGln: 0.766 ± 0.014	0.988CysArg: 0.988 ± 0.026	1.707CysSer: 1.707 ± 0.024	1.118CysThr: 1.118 ± 0.02	1.259CysVal: 1.259 ± 0.024	0.202CysTrp: 0.202 ± 0.005	0.645CysTyr: 0.645 ± 0.017	0.001CysXaa: 0.001 ± 0.0
Asp	2.565AspAla: 2.565 ± 0.022	0.948AspCys: 0.948 ± 0.015	3.496AspAsp: 3.496 ± 0.038	4.388AspGlu: 4.388 ± 0.034	2.142AspPhe: 2.142 ± 0.022	2.8AspGly: 2.8 ± 0.027	1.231AspHis: 1.231 ± 0.014	3.551AspIle: 3.551 ± 0.028	3.922AspLys: 3.922 ± 0.034	5.054AspLeu: 5.054 ± 0.033	1.288AspMet: 1.288 ± 0.015	2.894AspAsn: 2.894 ± 0.027	2.57AspPro: 2.57 ± 0.026	1.959AspGln: 1.959 ± 0.018	2.488AspArg: 2.488 ± 0.025	4.661AspSer: 4.661 ± 0.033	3.016AspThr: 3.016 ± 0.023	3.443AspVal: 3.443 ± 0.022	0.601AspTrp: 0.601 ± 0.011	1.834AspTyr: 1.834 ± 0.019	0.001AspXaa: 0.001 ± 0.0
Glu	3.571GluAla: 3.571 ± 0.03	1.134GluCys: 1.134 ± 0.027	4.491GluAsp: 4.491 ± 0.032	6.549GluGlu: 6.549 ± 0.079	2.241GluPhe: 2.241 ± 0.02	2.897GluGly: 2.897 ± 0.027	1.576GluHis: 1.576 ± 0.019	3.767GluIle: 3.767 ± 0.03	5.418GluLys: 5.418 ± 0.046	5.599GluLeu: 5.599 ± 0.035	1.635GluMet: 1.635 ± 0.016	3.966GluAsn: 3.966 ± 0.032	2.68GluPro: 2.68 ± 0.034	2.525GluGln: 2.525 ± 0.025	3.345GluArg: 3.345 ± 0.037	4.859GluSer: 4.859 ± 0.036	3.953GluThr: 3.953 ± 0.032	3.714GluVal: 3.714 ± 0.035	0.578GluTrp: 0.578 ± 0.01	2.017GluTyr: 2.017 ± 0.019	0.003GluXaa: 0.003 ± 0.001
Phe	1.854PheAla: 1.854 ± 0.015	0.811PheCys: 0.811 ± 0.013	2.106PheAsp: 2.106 ± 0.021	2.122PheGlu: 2.122 ± 0.023	1.533PhePhe: 1.533 ± 0.016	2.153PheGly: 2.153 ± 0.026	1.037PheHis: 1.037 ± 0.014	2.286PheIle: 2.286 ± 0.021	2.387PheLys: 2.387 ± 0.023	3.673PheLeu: 3.673 ± 0.024	0.812PheMet: 0.812 ± 0.011	2.017PheAsn: 2.017 ± 0.02	1.736PhePro: 1.736 ± 0.019	1.604PheGln: 1.604 ± 0.015	1.732PheArg: 1.732 ± 0.019	3.162PheSer: 3.162 ± 0.022	2.184PheThr: 2.184 ± 0.018	2.377PheVal: 2.377 ± 0.021	0.42PheTrp: 0.42 ± 0.009	1.364PheTyr: 1.364 ± 0.015	0.002PheXaa: 0.002 ± 0.001
Gly	2.973GlyAla: 2.973 ± 0.028	0.899GlyCys: 0.899 ± 0.012	2.927GlyAsp: 2.927 ± 0.025	3.157GlyGlu: 3.157 ± 0.029	2.106GlyPhe: 2.106 ± 0.021	4.485GlyGly: 4.485 ± 0.068	1.381GlyHis: 1.381 ± 0.016	2.74GlyIle: 2.74 ± 0.023	3.654GlyLys: 3.654 ± 0.035	4.2GlyLeu: 4.2 ± 0.032	1.238GlyMet: 1.238 ± 0.042	2.702GlyAsn: 2.702 ± 0.03	2.414GlyPro: 2.414 ± 0.036	1.897GlyGln: 1.897 ± 0.024	2.627GlyArg: 2.627 ± 0.023	4.539GlySer: 4.539 ± 0.046	2.999GlyThr: 2.999 ± 0.029	3.268GlyVal: 3.268 ± 0.026	0.544GlyTrp: 0.544 ± 0.009	1.915GlyTyr: 1.915 ± 0.025	0.002GlyXaa: 0.002 ± 0.0
His	1.237HisAla: 1.237 ± 0.017	0.614HisCys: 0.614 ± 0.009	1.14HisAsp: 1.14 ± 0.012	1.436HisGlu: 1.436 ± 0.016	1.073HisPhe: 1.073 ± 0.013	1.339HisGly: 1.339 ± 0.016	1.131HisHis: 1.131 ± 0.023	1.585HisIle: 1.585 ± 0.015	1.598HisLys: 1.598 ± 0.019	2.626HisLeu: 2.626 ± 0.022	0.698HisMet: 0.698 ± 0.013	1.338HisAsn: 1.338 ± 0.015	1.434HisPro: 1.434 ± 0.017	1.171HisGln: 1.171 ± 0.015	1.367HisArg: 1.367 ± 0.017	2.249HisSer: 2.249 ± 0.021	1.499HisThr: 1.499 ± 0.017	1.611HisVal: 1.611 ± 0.015	0.297HisTrp: 0.297 ± 0.007	0.937HisTyr: 0.937 ± 0.014	0.001HisXaa: 0.001 ± 0.0
Ile	2.954IleAla: 2.954 ± 0.021	1.178IleCys: 1.178 ± 0.018	3.045IleAsp: 3.045 ± 0.024	3.627IleGlu: 3.627 ± 0.028	2.167IlePhe: 2.167 ± 0.023	2.618IleGly: 2.618 ± 0.021	1.525IleHis: 1.525 ± 0.015	3.247IleIle: 3.247 ± 0.028	3.799IleLys: 3.799 ± 0.027	5.343IleLeu: 5.343 ± 0.037	1.192IleMet: 1.192 ± 0.014	3.003IleAsn: 3.003 ± 0.032	3.065IlePro: 3.065 ± 0.027	2.518IleGln: 2.518 ± 0.025	2.644IleArg: 2.644 ± 0.02	4.519IleSer: 4.519 ± 0.026	3.179IleThr: 3.179 ± 0.027	3.475IleVal: 3.475 ± 0.024	0.508IleTrp: 0.508 ± 0.008	1.691IleTyr: 1.691 ± 0.017	0.004IleXaa: 0.004 ± 0.001
Lys	3.555LysAla: 3.555 ± 0.029	1.431LysCys: 1.431 ± 0.022	3.733LysAsp: 3.733 ± 0.034	5.169LysGlu: 5.169 ± 0.044	2.443LysPhe: 2.443 ± 0.022	2.671LysGly: 2.671 ± 0.029	1.908LysHis: 1.908 ± 0.02	4.009LysIle: 4.009 ± 0.037	6.197LysLys: 6.197 ± 0.064	6.274LysLeu: 6.274 ± 0.033	1.67LysMet: 1.67 ± 0.016	3.602LysAsn: 3.602 ± 0.034	3.757LysPro: 3.757 ± 0.048	2.926LysGln: 2.926 ± 0.022	3.822LysArg: 3.822 ± 0.028	5.742LysSer: 5.742 ± 0.047	4.284LysThr: 4.284 ± 0.034	3.968LysVal: 3.968 ± 0.029	0.659LysTrp: 0.659 ± 0.011	2.505LysTyr: 2.505 ± 0.024	0.004LysXaa: 0.004 ± 0.001
Leu	5.151LeuAla: 5.151 ± 0.036	1.932LeuCys: 1.932 ± 0.021	4.995LeuAsp: 4.995 ± 0.038	5.851LeuGlu: 5.851 ± 0.039	3.422LeuPhe: 3.422 ± 0.028	4.448LeuGly: 4.448 ± 0.032	2.354LeuHis: 2.354 ± 0.02	4.684LeuIle: 4.684 ± 0.028	6.44LeuLys: 6.44 ± 0.041	8.595LeuLeu: 8.595 ± 0.056	1.994LeuMet: 1.994 ± 0.018	4.85LeuAsn: 4.85 ± 0.028	4.625LeuPro: 4.625 ± 0.036	3.87LeuGln: 3.87 ± 0.029	4.557LeuArg: 4.557 ± 0.028	7.759LeuSer: 7.759 ± 0.042	5.031LeuThr: 5.031 ± 0.026	5.295LeuVal: 5.295 ± 0.034	0.881LeuTrp: 0.881 ± 0.014	2.836LeuTyr: 2.836 ± 0.027	0.004LeuXaa: 0.004 ± 0.001
Met	1.387MetAla: 1.387 ± 0.014	0.462MetCys: 0.462 ± 0.008	1.318MetAsp: 1.318 ± 0.015	1.595MetGlu: 1.595 ± 0.016	1.005MetPhe: 1.005 ± 0.013	1.228MetGly: 1.228 ± 0.026	0.447MetHis: 0.447 ± 0.008	1.137MetIle: 1.137 ± 0.012	1.826MetLys: 1.826 ± 0.018	1.908MetLeu: 1.908 ± 0.017	0.663MetMet: 0.663 ± 0.017	1.331MetAsn: 1.331 ± 0.018	0.979MetPro: 0.979 ± 0.026	0.809MetGln: 0.809 ± 0.013	1.133MetArg: 1.133 ± 0.011	2.045MetSer: 2.045 ± 0.019	1.273MetThr: 1.273 ± 0.013	1.249MetVal: 1.249 ± 0.015	0.22MetTrp: 0.22 ± 0.006	0.752MetTyr: 0.752 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	2.778AsnAla: 2.778 ± 0.023	0.89AsnCys: 0.89 ± 0.015	2.645AsnAsp: 2.645 ± 0.023	3.583AsnGlu: 3.583 ± 0.034	2.028AsnPhe: 2.028 ± 0.02	2.874AsnGly: 2.874 ± 0.033	1.361AsnHis: 1.361 ± 0.017	3.713AsnIle: 3.713 ± 0.031	3.955AsnLys: 3.955 ± 0.039	4.796AsnLeu: 4.796 ± 0.033	1.273AsnMet: 1.273 ± 0.018	3.807AsnAsn: 3.807 ± 0.059	2.714AsnPro: 2.714 ± 0.04	2.416AsnGln: 2.416 ± 0.025	2.387AsnArg: 2.387 ± 0.021	4.653AsnSer: 4.653 ± 0.038	3.354AsnThr: 3.354 ± 0.03	3.499AsnVal: 3.499 ± 0.023	0.449AsnTrp: 0.449 ± 0.01	1.781AsnTyr: 1.781 ± 0.022	0.002AsnXaa: 0.002 ± 0.001
Pro	3.139ProAla: 3.139 ± 0.041	0.923ProCys: 0.923 ± 0.028	2.798ProAsp: 2.798 ± 0.026	3.343ProGlu: 3.343 ± 0.042	1.711ProPhe: 1.711 ± 0.022	3.149ProGly: 3.149 ± 0.063	1.384ProHis: 1.384 ± 0.018	2.515ProIle: 2.515 ± 0.022	3.032ProLys: 3.032 ± 0.034	4.238ProLeu: 4.238 ± 0.029	1.034ProMet: 1.034 ± 0.017	2.827ProAsn: 2.827 ± 0.032	4.623ProPro: 4.623 ± 0.075	2.129ProGln: 2.129 ± 0.027	2.433ProArg: 2.433 ± 0.03	5.305ProSer: 5.305 ± 0.054	3.249ProThr: 3.249 ± 0.032	3.487ProVal: 3.487 ± 0.033	0.46ProTrp: 0.46 ± 0.008	1.7ProTyr: 1.7 ± 0.028	0.002ProXaa: 0.002 ± 0.001
Gln	2.314GlnAla: 2.314 ± 0.022	0.951GlnCys: 0.951 ± 0.021	2.16GlnAsp: 2.16 ± 0.019	2.769GlnGlu: 2.769 ± 0.024	1.511GlnPhe: 1.511 ± 0.015	1.977GlnGly: 1.977 ± 0.021	1.2GlnHis: 1.2 ± 0.019	2.287GlnIle: 2.287 ± 0.021	2.549GlnLys: 2.549 ± 0.024	3.703GlnLeu: 3.703 ± 0.026	1.041GlnMet: 1.041 ± 0.011	2.376GlnAsn: 2.376 ± 0.025	2.005GlnPro: 2.005 ± 0.028	2.613GlnGln: 2.613 ± 0.062	2.072GlnArg: 2.072 ± 0.022	3.28GlnSer: 3.28 ± 0.028	2.432GlnThr: 2.432 ± 0.024	2.546GlnVal: 2.546 ± 0.024	0.436GlnTrp: 0.436 ± 0.008	1.48GlnTyr: 1.48 ± 0.017	0.001GlnXaa: 0.001 ± 0.0
Arg	2.484ArgAla: 2.484 ± 0.021	0.931ArgCys: 0.931 ± 0.019	2.682ArgAsp: 2.682 ± 0.025	3.193ArgGlu: 3.193 ± 0.025	1.786ArgPhe: 1.786 ± 0.018	2.557ArgGly: 2.557 ± 0.025	1.478ArgHis: 1.478 ± 0.015	2.648ArgIle: 2.648 ± 0.021	4.028ArgLys: 4.028 ± 0.032	4.272ArgLeu: 4.272 ± 0.029	1.134ArgMet: 1.134 ± 0.013	2.845ArgAsn: 2.845 ± 0.027	2.474ArgPro: 2.474 ± 0.031	2.011ArgGln: 2.011 ± 0.02	3.468ArgArg: 3.468 ± 0.035	4.101ArgSer: 4.101 ± 0.046	2.808ArgThr: 2.808 ± 0.023	2.77ArgVal: 2.77 ± 0.022	0.487ArgTrp: 0.487 ± 0.009	1.668ArgTyr: 1.668 ± 0.016	0.004ArgXaa: 0.004 ± 0.001
Ser	4.491SerAla: 4.491 ± 0.033	1.644SerCys: 1.644 ± 0.027	4.79SerAsp: 4.79 ± 0.031	5.104SerGlu: 5.104 ± 0.039	3.015SerPhe: 3.015 ± 0.025	4.957SerGly: 4.957 ± 0.039	2.304SerHis: 2.304 ± 0.021	4.353SerIle: 4.353 ± 0.028	5.613SerLys: 5.613 ± 0.042	7.418SerLeu: 7.418 ± 0.041	1.775SerMet: 1.775 ± 0.017	4.997SerAsn: 4.997 ± 0.041	5.205SerPro: 5.205 ± 0.068	3.547SerGln: 3.547 ± 0.03	4.18SerArg: 4.18 ± 0.043	10.252SerSer: 10.252 ± 0.095	5.631SerThr: 5.631 ± 0.038	5.032SerVal: 5.032 ± 0.032	0.766SerTrp: 0.766 ± 0.011	2.596SerTyr: 2.596 ± 0.028	0.003SerXaa: 0.003 ± 0.001
Thr	3.171ThrAla: 3.171 ± 0.023	1.224ThrCys: 1.224 ± 0.019	2.942ThrAsp: 2.942 ± 0.025	3.567ThrGlu: 3.567 ± 0.035	2.125ThrPhe: 2.125 ± 0.021	3.21ThrGly: 3.21 ± 0.03	1.486ThrHis: 1.486 ± 0.017	3.164ThrIle: 3.164 ± 0.028	3.853ThrLys: 3.853 ± 0.035	5.467ThrLeu: 5.467 ± 0.031	1.225ThrMet: 1.225 ± 0.015	3.222ThrAsn: 3.222 ± 0.026	3.954ThrPro: 3.954 ± 0.041	2.314ThrGln: 2.314 ± 0.021	2.719ThrArg: 2.719 ± 0.022	5.918ThrSer: 5.918 ± 0.046	4.245ThrThr: 4.245 ± 0.049	3.657ThrVal: 3.657 ± 0.026	0.558ThrTrp: 0.558 ± 0.009	1.75ThrTyr: 1.75 ± 0.019	0.002ThrXaa: 0.002 ± 0.001
Val	3.382ValAla: 3.382 ± 0.027	1.363ValCys: 1.363 ± 0.021	3.342ValAsp: 3.342 ± 0.023	3.982ValGlu: 3.982 ± 0.034	2.373ValPhe: 2.373 ± 0.021	2.824ValGly: 2.824 ± 0.024	1.61ValHis: 1.61 ± 0.017	3.37ValIle: 3.37 ± 0.025	4.255ValLys: 4.255 ± 0.035	5.505ValLeu: 5.505 ± 0.035	1.337ValMet: 1.337 ± 0.015	3.176ValAsn: 3.176 ± 0.026	3.208ValPro: 3.208 ± 0.03	2.583ValGln: 2.583 ± 0.021	2.919ValArg: 2.919 ± 0.027	4.927ValSer: 4.927 ± 0.031	3.874ValThr: 3.874 ± 0.03	3.777ValVal: 3.777 ± 0.033	0.634ValTrp: 0.634 ± 0.009	1.895ValTyr: 1.895 ± 0.018	0.003ValXaa: 0.003 ± 0.001
Trp	0.467TrpAla: 0.467 ± 0.008	0.207TrpCys: 0.207 ± 0.005	0.547TrpAsp: 0.547 ± 0.009	0.553TrpGlu: 0.553 ± 0.009	0.43TrpPhe: 0.43 ± 0.009	0.489TrpGly: 0.489 ± 0.01	0.22TrpHis: 0.22 ± 0.006	0.57TrpIle: 0.57 ± 0.01	0.744TrpLys: 0.744 ± 0.01	0.924TrpLeu: 0.924 ± 0.013	0.267TrpMet: 0.267 ± 0.005	0.596TrpAsn: 0.596 ± 0.01	0.386TrpPro: 0.386 ± 0.008	0.363TrpGln: 0.363 ± 0.008	0.56TrpArg: 0.56 ± 0.009	0.795TrpSer: 0.795 ± 0.013	0.604TrpThr: 0.604 ± 0.009	0.545TrpVal: 0.545 ± 0.01	0.162TrpTrp: 0.162 ± 0.005	0.347TrpTyr: 0.347 ± 0.008	0.001TrpXaa: 0.001 ± 0.0
Tyr	1.706TyrAla: 1.706 ± 0.022	0.743TyrCys: 0.743 ± 0.011	1.764TyrAsp: 1.764 ± 0.018	2.038TyrGlu: 2.038 ± 0.018	1.478TyrPhe: 1.478 ± 0.016	1.797TyrGly: 1.797 ± 0.024	0.892TyrHis: 0.892 ± 0.013	1.739TyrIle: 1.739 ± 0.017	2.129TyrLys: 2.129 ± 0.019	3.102TyrLeu: 3.102 ± 0.028	0.742TyrMet: 0.742 ± 0.01	1.881TyrAsn: 1.881 ± 0.027	1.589TyrPro: 1.589 ± 0.027	1.389TyrGln: 1.389 ± 0.015	1.652TyrArg: 1.652 ± 0.017	2.606TyrSer: 2.606 ± 0.024	1.767TyrThr: 1.767 ± 0.019	1.979TyrVal: 1.979 ± 0.018	0.377TyrTrp: 0.377 ± 0.008	1.318TyrTyr: 1.318 ± 0.016	0.002TyrXaa: 0.002 ± 0.001
Xaa	0.002XaaAla: 0.002 ± 0.001	0.001XaaCys: 0.001 ± 0.0	0.002XaaAsp: 0.002 ± 0.0	0.002XaaGlu: 0.002 ± 0.001	0.002XaaPhe: 0.002 ± 0.001	0.002XaaGly: 0.002 ± 0.001	0.001XaaHis: 0.001 ± 0.0	0.003XaaIle: 0.003 ± 0.001	0.003XaaLys: 0.003 ± 0.001	0.004XaaLeu: 0.004 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.002XaaAsn: 0.002 ± 0.001	0.003XaaPro: 0.003 ± 0.001	0.002XaaGln: 0.002 ± 0.0	0.003XaaArg: 0.003 ± 0.001	0.004XaaSer: 0.004 ± 0.001	0.003XaaThr: 0.003 ± 0.001	0.004XaaVal: 0.004 ± 0.001	0.001XaaTrp: 0.001 ± 0.0	0.002XaaTyr: 0.002 ± 0.0	0.002XaaXaa: 0.002 ± 0.001

Statistics based on 21517 proteins (8003745 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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