Amino acid dipepetide frequency for Lujinxingia litoralis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.911AlaAla: 11.911 ± 0.138	1.459AlaCys: 1.459 ± 0.046	5.777AlaAsp: 5.777 ± 0.074	7.981AlaGlu: 7.981 ± 0.101	3.702AlaPhe: 3.702 ± 0.054	8.967AlaGly: 8.967 ± 0.104	2.648AlaHis: 2.648 ± 0.053	4.927AlaIle: 4.927 ± 0.066	1.846AlaLys: 1.846 ± 0.044	14.757AlaLeu: 14.757 ± 0.173	2.746AlaMet: 2.746 ± 0.051	2.362AlaAsn: 2.362 ± 0.043	6.617AlaPro: 6.617 ± 0.1	4.465AlaGln: 4.465 ± 0.064	10.143AlaArg: 10.143 ± 0.114	6.818AlaSer: 6.818 ± 0.073	5.587AlaThr: 5.587 ± 0.071	6.629AlaVal: 6.629 ± 0.094	1.41AlaTrp: 1.41 ± 0.033	2.481AlaTyr: 2.481 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	1.358CysAla: 1.358 ± 0.045	0.108CysCys: 0.108 ± 0.01	0.797CysAsp: 0.797 ± 0.035	0.902CysGlu: 0.902 ± 0.037	0.301CysPhe: 0.301 ± 0.015	1.293CysGly: 1.293 ± 0.047	0.252CysHis: 0.252 ± 0.016	0.343CysIle: 0.343 ± 0.019	0.178CysLys: 0.178 ± 0.012	0.835CysLeu: 0.835 ± 0.036	0.16CysMet: 0.16 ± 0.011	0.297CysAsn: 0.297 ± 0.017	0.687CysPro: 0.687 ± 0.028	0.513CysGln: 0.513 ± 0.03	0.645CysArg: 0.645 ± 0.026	0.7CysSer: 0.7 ± 0.036	0.622CysThr: 0.622 ± 0.031	0.89CysVal: 0.89 ± 0.033	0.18CysTrp: 0.18 ± 0.02	0.254CysTyr: 0.254 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	7.782AspAla: 7.782 ± 0.092	0.625AspCys: 0.625 ± 0.037	3.953AspAsp: 3.953 ± 0.073	4.872AspGlu: 4.872 ± 0.063	2.273AspPhe: 2.273 ± 0.045	4.348AspGly: 4.348 ± 0.079	1.425AspHis: 1.425 ± 0.037	2.352AspIle: 2.352 ± 0.043	1.036AspLys: 1.036 ± 0.032	6.049AspLeu: 6.049 ± 0.074	0.972AspMet: 0.972 ± 0.025	1.23AspAsn: 1.23 ± 0.034	3.57AspPro: 3.57 ± 0.055	2.197AspGln: 2.197 ± 0.044	3.838AspArg: 3.838 ± 0.055	2.371AspSer: 2.371 ± 0.048	2.921AspThr: 2.921 ± 0.062	4.421AspVal: 4.421 ± 0.062	0.806AspTrp: 0.806 ± 0.024	1.459AspTyr: 1.459 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	9.209GluAla: 9.209 ± 0.119	0.671GluCys: 0.671 ± 0.036	3.912GluAsp: 3.912 ± 0.06	5.775GluGlu: 5.775 ± 0.1	2.084GluPhe: 2.084 ± 0.04	6.037GluGly: 6.037 ± 0.087	1.92GluHis: 1.92 ± 0.037	3.006GluIle: 3.006 ± 0.047	1.777GluLys: 1.777 ± 0.043	9.291GluLeu: 9.291 ± 0.101	1.501GluMet: 1.501 ± 0.033	1.481GluAsn: 1.481 ± 0.034	3.86GluPro: 3.86 ± 0.07	2.821GluGln: 2.821 ± 0.053	7.327GluArg: 7.327 ± 0.095	3.984GluSer: 3.984 ± 0.057	2.947GluThr: 2.947 ± 0.047	6.273GluVal: 6.273 ± 0.084	0.65GluTrp: 0.65 ± 0.021	1.228GluTyr: 1.228 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	3.527PheAla: 3.527 ± 0.05	0.463PheCys: 0.463 ± 0.02	2.711PheAsp: 2.711 ± 0.041	3.341PheGlu: 3.341 ± 0.05	1.441PhePhe: 1.441 ± 0.035	3.292PheGly: 3.292 ± 0.042	0.689PheHis: 0.689 ± 0.02	1.337PheIle: 1.337 ± 0.036	0.912PheLys: 0.912 ± 0.029	2.879PheLeu: 2.879 ± 0.053	0.725PheMet: 0.725 ± 0.024	1.101PheAsn: 1.101 ± 0.032	1.374PhePro: 1.374 ± 0.037	1.021PheGln: 1.021 ± 0.024	1.884PheArg: 1.884 ± 0.043	2.085PheSer: 2.085 ± 0.039	1.637PheThr: 1.637 ± 0.039	2.567PheVal: 2.567 ± 0.048	0.506PheTrp: 0.506 ± 0.019	0.964PheTyr: 0.964 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	8.985GlyAla: 8.985 ± 0.115	1.124GlyCys: 1.124 ± 0.042	4.901GlyAsp: 4.901 ± 0.074	6.743GlyGlu: 6.743 ± 0.099	2.937GlyPhe: 2.937 ± 0.044	6.904GlyGly: 6.904 ± 0.095	1.751GlyHis: 1.751 ± 0.036	3.136GlyIle: 3.136 ± 0.05	2.135GlyLys: 2.135 ± 0.046	8.419GlyLeu: 8.419 ± 0.087	1.915GlyMet: 1.915 ± 0.041	1.806GlyAsn: 1.806 ± 0.044	3.698GlyPro: 3.698 ± 0.064	3.796GlyGln: 3.796 ± 0.057	5.676GlyArg: 5.676 ± 0.074	4.408GlySer: 4.408 ± 0.064	4.12GlyThr: 4.12 ± 0.064	6.302GlyVal: 6.302 ± 0.086	1.318GlyTrp: 1.318 ± 0.036	2.134GlyTyr: 2.134 ± 0.044	0.001GlyXaa: 0.001 ± 0.001
His	2.313HisAla: 2.313 ± 0.048	0.273HisCys: 0.273 ± 0.016	1.275HisAsp: 1.275 ± 0.034	1.281HisGlu: 1.281 ± 0.03	0.954HisPhe: 0.954 ± 0.023	1.66HisGly: 1.66 ± 0.037	0.792HisHis: 0.792 ± 0.026	0.959HisIle: 0.959 ± 0.026	0.414HisLys: 0.414 ± 0.018	2.78HisLeu: 2.78 ± 0.05	0.362HisMet: 0.362 ± 0.017	0.51HisAsn: 0.51 ± 0.019	1.708HisPro: 1.708 ± 0.039	1.074HisGln: 1.074 ± 0.033	1.96HisArg: 1.96 ± 0.04	1.071HisSer: 1.071 ± 0.029	1.278HisThr: 1.278 ± 0.036	1.39HisVal: 1.39 ± 0.037	0.31HisTrp: 0.31 ± 0.016	0.66HisTyr: 0.66 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	4.945IleAla: 4.945 ± 0.062	0.577IleCys: 0.577 ± 0.021	3.386IleAsp: 3.386 ± 0.055	3.603IleGlu: 3.603 ± 0.052	1.712IlePhe: 1.712 ± 0.038	3.182IleGly: 3.182 ± 0.05	0.9IleHis: 0.9 ± 0.024	1.686IleIle: 1.686 ± 0.04	1.072IleLys: 1.072 ± 0.032	3.494IleLeu: 3.494 ± 0.05	0.645IleMet: 0.645 ± 0.024	1.238IleAsn: 1.238 ± 0.036	2.039IlePro: 2.039 ± 0.035	1.181IleGln: 1.181 ± 0.031	2.357IleArg: 2.357 ± 0.047	2.411IleSer: 2.411 ± 0.043	2.258IleThr: 2.258 ± 0.044	2.852IleVal: 2.852 ± 0.045	0.536IleTrp: 0.536 ± 0.021	1.112IleTyr: 1.112 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	2.39LysAla: 2.39 ± 0.051	0.135LysCys: 0.135 ± 0.009	1.079LysAsp: 1.079 ± 0.032	1.499LysGlu: 1.499 ± 0.043	0.617LysPhe: 0.617 ± 0.026	1.62LysGly: 1.62 ± 0.041	0.491LysHis: 0.491 ± 0.016	1.211LysIle: 1.211 ± 0.036	1.032LysLys: 1.032 ± 0.046	2.314LysLeu: 2.314 ± 0.041	0.576LysMet: 0.576 ± 0.02	0.636LysAsn: 0.636 ± 0.022	1.162LysPro: 1.162 ± 0.03	0.654LysGln: 0.654 ± 0.02	1.868LysArg: 1.868 ± 0.037	1.332LysSer: 1.332 ± 0.038	1.249LysThr: 1.249 ± 0.031	1.892LysVal: 1.892 ± 0.043	0.205LysTrp: 0.205 ± 0.012	0.443LysTyr: 0.443 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	12.271LeuAla: 12.271 ± 0.136	0.946LeuCys: 0.946 ± 0.028	6.413LeuAsp: 6.413 ± 0.081	8.035LeuGlu: 8.035 ± 0.105	3.403LeuPhe: 3.403 ± 0.056	8.865LeuGly: 8.865 ± 0.105	2.458LeuHis: 2.458 ± 0.051	4.35LeuIle: 4.35 ± 0.054	3.06LeuLys: 3.06 ± 0.053	10.152LeuLeu: 10.152 ± 0.118	2.184LeuMet: 2.184 ± 0.04	3.001LeuAsn: 3.001 ± 0.052	5.563LeuPro: 5.563 ± 0.073	3.666LeuGln: 3.666 ± 0.062	8.145LeuArg: 8.145 ± 0.099	7.286LeuSer: 7.286 ± 0.088	5.653LeuThr: 5.653 ± 0.083	7.463LeuVal: 7.463 ± 0.093	1.253LeuTrp: 1.253 ± 0.032	2.361LeuTyr: 2.361 ± 0.043	0.0LeuXaa: 0.0 ± 0.0
Met	2.443MetAla: 2.443 ± 0.05	0.182MetCys: 0.182 ± 0.01	0.816MetAsp: 0.816 ± 0.026	1.3MetGlu: 1.3 ± 0.034	0.57MetPhe: 0.57 ± 0.022	1.737MetGly: 1.737 ± 0.036	0.397MetHis: 0.397 ± 0.017	0.952MetIle: 0.952 ± 0.029	0.689MetLys: 0.689 ± 0.023	2.214MetLeu: 2.214 ± 0.043	0.661MetMet: 0.661 ± 0.025	0.589MetAsn: 0.589 ± 0.02	1.108MetPro: 1.108 ± 0.029	0.646MetGln: 0.646 ± 0.023	1.699MetArg: 1.699 ± 0.034	1.534MetSer: 1.534 ± 0.031	1.257MetThr: 1.257 ± 0.029	1.727MetVal: 1.727 ± 0.037	0.228MetTrp: 0.228 ± 0.014	0.359MetTyr: 0.359 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	2.797AsnAla: 2.797 ± 0.049	0.237AsnCys: 0.237 ± 0.015	1.492AsnAsp: 1.492 ± 0.035	1.382AsnGlu: 1.382 ± 0.033	0.966AsnPhe: 0.966 ± 0.025	1.581AsnGly: 1.581 ± 0.042	0.565AsnHis: 0.565 ± 0.019	1.142AsnIle: 1.142 ± 0.031	0.487AsnLys: 0.487 ± 0.019	2.708AsnLeu: 2.708 ± 0.047	0.417AsnMet: 0.417 ± 0.017	0.696AsnAsn: 0.696 ± 0.023	1.771AsnPro: 1.771 ± 0.041	0.878AsnGln: 0.878 ± 0.027	1.558AsnArg: 1.558 ± 0.04	1.181AsnSer: 1.181 ± 0.031	1.319AsnThr: 1.319 ± 0.029	1.7AsnVal: 1.7 ± 0.038	0.257AsnTrp: 0.257 ± 0.012	0.629AsnTyr: 0.629 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	6.226ProAla: 6.226 ± 0.099	0.392ProCys: 0.392 ± 0.017	3.769ProAsp: 3.769 ± 0.067	5.041ProGlu: 5.041 ± 0.075	1.699ProPhe: 1.699 ± 0.032	5.26ProGly: 5.26 ± 0.079	1.164ProHis: 1.164 ± 0.035	1.864ProIle: 1.864 ± 0.036	0.911ProLys: 0.911 ± 0.028	4.963ProLeu: 4.963 ± 0.07	1.175ProMet: 1.175 ± 0.029	1.21ProAsn: 1.21 ± 0.035	3.021ProPro: 3.021 ± 0.07	2.105ProGln: 2.105 ± 0.044	3.711ProArg: 3.711 ± 0.062	3.039ProSer: 3.039 ± 0.057	3.14ProThr: 3.14 ± 0.053	3.828ProVal: 3.828 ± 0.053	0.724ProTrp: 0.724 ± 0.024	1.164ProTyr: 1.164 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	5.271GlnAla: 5.271 ± 0.086	0.378GlnCys: 0.378 ± 0.029	1.586GlnAsp: 1.586 ± 0.032	2.552GlnGlu: 2.552 ± 0.057	0.78GlnPhe: 0.78 ± 0.024	3.48GlnGly: 3.48 ± 0.054	0.772GlnHis: 0.772 ± 0.022	1.69GlnIle: 1.69 ± 0.039	0.933GlnLys: 0.933 ± 0.029	3.628GlnLeu: 3.628 ± 0.059	0.824GlnMet: 0.824 ± 0.022	0.906GlnAsn: 0.906 ± 0.024	1.846GlnPro: 1.846 ± 0.042	1.36GlnGln: 1.36 ± 0.034	3.295GlnArg: 3.295 ± 0.054	1.914GlnSer: 1.914 ± 0.039	1.934GlnThr: 1.934 ± 0.039	3.277GlnVal: 3.277 ± 0.051	0.465GlnTrp: 0.465 ± 0.021	0.566GlnTyr: 0.566 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	9.175ArgAla: 9.175 ± 0.101	0.821ArgCys: 0.821 ± 0.032	4.084ArgAsp: 4.084 ± 0.064	5.425ArgGlu: 5.425 ± 0.078	3.002ArgPhe: 3.002 ± 0.047	5.661ArgGly: 5.661 ± 0.075	1.893ArgHis: 1.893 ± 0.038	3.098ArgIle: 3.098 ± 0.054	1.625ArgLys: 1.625 ± 0.043	8.388ArgLeu: 8.388 ± 0.093	1.591ArgMet: 1.591 ± 0.039	1.484ArgAsn: 1.484 ± 0.034	3.805ArgPro: 3.805 ± 0.056	3.628ArgGln: 3.628 ± 0.057	6.501ArgArg: 6.501 ± 0.084	3.978ArgSer: 3.978 ± 0.062	3.282ArgThr: 3.282 ± 0.057	6.128ArgVal: 6.128 ± 0.079	1.385ArgTrp: 1.385 ± 0.034	2.078ArgTyr: 2.078 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	6.508SerAla: 6.508 ± 0.08	0.845SerCys: 0.845 ± 0.044	3.152SerAsp: 3.152 ± 0.052	4.024SerGlu: 4.024 ± 0.058	2.158SerPhe: 2.158 ± 0.04	5.265SerGly: 5.265 ± 0.079	1.169SerHis: 1.169 ± 0.028	2.072SerIle: 2.072 ± 0.036	1.147SerLys: 1.147 ± 0.038	5.602SerLeu: 5.602 ± 0.079	1.224SerMet: 1.224 ± 0.027	1.266SerAsn: 1.266 ± 0.03	3.956SerPro: 3.956 ± 0.069	2.013SerGln: 2.013 ± 0.039	3.844SerArg: 3.844 ± 0.047	3.546SerSer: 3.546 ± 0.068	3.038SerThr: 3.038 ± 0.048	3.968SerVal: 3.968 ± 0.059	0.859SerTrp: 0.859 ± 0.023	1.443SerTyr: 1.443 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	4.337ThrAla: 4.337 ± 0.061	0.714ThrCys: 0.714 ± 0.036	2.616ThrAsp: 2.616 ± 0.053	2.966ThrGlu: 2.966 ± 0.047	1.998ThrPhe: 1.998 ± 0.042	4.059ThrGly: 4.059 ± 0.059	1.258ThrHis: 1.258 ± 0.033	2.39ThrIle: 2.39 ± 0.042	0.771ThrLys: 0.771 ± 0.024	6.772ThrLeu: 6.772 ± 0.075	0.982ThrMet: 0.982 ± 0.025	1.176ThrAsn: 1.176 ± 0.03	3.505ThrPro: 3.505 ± 0.055	1.528ThrGln: 1.528 ± 0.032	3.938ThrArg: 3.938 ± 0.052	3.206ThrSer: 3.206 ± 0.054	3.005ThrThr: 3.005 ± 0.054	3.087ThrVal: 3.087 ± 0.051	0.662ThrTrp: 0.662 ± 0.024	1.504ThrTyr: 1.504 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	8.285ValAla: 8.285 ± 0.097	0.902ValCys: 0.902 ± 0.033	4.748ValAsp: 4.748 ± 0.063	6.302ValGlu: 6.302 ± 0.084	2.42ValPhe: 2.42 ± 0.042	6.125ValGly: 6.125 ± 0.09	1.604ValHis: 1.604 ± 0.035	3.299ValIle: 3.299 ± 0.053	1.538ValLys: 1.538 ± 0.039	7.252ValLeu: 7.252 ± 0.101	1.625ValMet: 1.625 ± 0.033	1.817ValAsn: 1.817 ± 0.041	3.33ValPro: 3.33 ± 0.052	2.261ValGln: 2.261 ± 0.04	5.423ValArg: 5.423 ± 0.081	4.228ValSer: 4.228 ± 0.064	3.328ValThr: 3.328 ± 0.054	6.42ValVal: 6.42 ± 0.091	0.839ValTrp: 0.839 ± 0.021	1.683ValTyr: 1.683 ± 0.033	0.001ValXaa: 0.001 ± 0.001
Trp	1.214TrpAla: 1.214 ± 0.032	0.133TrpCys: 0.133 ± 0.011	0.563TrpAsp: 0.563 ± 0.02	1.045TrpGlu: 1.045 ± 0.027	0.381TrpPhe: 0.381 ± 0.018	0.956TrpGly: 0.956 ± 0.031	0.288TrpHis: 0.288 ± 0.013	0.501TrpIle: 0.501 ± 0.02	0.375TrpLys: 0.375 ± 0.019	1.51TrpLeu: 1.51 ± 0.036	0.377TrpMet: 0.377 ± 0.015	0.319TrpAsn: 0.319 ± 0.015	0.688TrpPro: 0.688 ± 0.025	0.56TrpGln: 0.56 ± 0.022	1.182TrpArg: 1.182 ± 0.031	0.866TrpSer: 0.866 ± 0.028	0.696TrpThr: 0.696 ± 0.022	0.975TrpVal: 0.975 ± 0.028	0.243TrpTrp: 0.243 ± 0.015	0.261TrpTyr: 0.261 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.286TyrAla: 2.286 ± 0.04	0.33TyrCys: 0.33 ± 0.019	1.47TyrAsp: 1.47 ± 0.036	1.682TyrGlu: 1.682 ± 0.038	1.056TyrPhe: 1.056 ± 0.028	1.915TyrGly: 1.915 ± 0.041	0.591TyrHis: 0.591 ± 0.021	0.872TyrIle: 0.872 ± 0.023	0.464TyrLys: 0.464 ± 0.018	2.522TyrLeu: 2.522 ± 0.048	0.446TyrMet: 0.446 ± 0.017	0.643TyrAsn: 0.643 ± 0.02	1.096TyrPro: 1.096 ± 0.035	1.09TyrGln: 1.09 ± 0.028	2.034TyrArg: 2.034 ± 0.042	1.142TyrSer: 1.142 ± 0.03	1.2TyrThr: 1.2 ± 0.034	1.644TyrVal: 1.644 ± 0.029	0.3TyrTrp: 0.3 ± 0.015	0.699TyrTyr: 0.699 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.001	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.001	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3776 proteins (1447238 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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