Amino acid dipepetide frequency for Torque teno sus virus SH0822/2008

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.529AlaAla: 8.529 ± 7.512
0.0AlaCys: 0.0 ± 0.0
5.33AlaAsp: 5.33 ± 1.588
5.33AlaGlu: 5.33 ± 1.483
3.198AlaPhe: 3.198 ± 1.72
2.132AlaGly: 2.132 ± 1.147
0.0AlaHis: 0.0 ± 0.0
4.264AlaIle: 4.264 ± 3.192
2.132AlaLys: 2.132 ± 1.147
5.33AlaLeu: 5.33 ± 4.323
2.132AlaMet: 2.132 ± 2.828
1.066AlaAsn: 1.066 ± 0.573
2.132AlaPro: 2.132 ± 1.147
2.132AlaGln: 2.132 ± 1.147
4.264AlaArg: 4.264 ± 2.294
3.198AlaSer: 3.198 ± 1.72
6.397AlaThr: 6.397 ± 8.485
3.198AlaVal: 3.198 ± 3.752
3.198AlaTrp: 3.198 ± 2.348
1.066AlaTyr: 1.066 ± 0.573
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
2.132CysGly: 2.132 ± 2.828
0.0CysHis: 0.0 ± 0.0
2.132CysIle: 2.132 ± 1.147
1.066CysLys: 1.066 ± 0.573
3.198CysLeu: 3.198 ± 2.274
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
3.198CysArg: 3.198 ± 3.752
1.066CysSer: 1.066 ± 1.382
0.0CysThr: 0.0 ± 0.0
2.132CysVal: 2.132 ± 1.147
0.0CysTrp: 0.0 ± 0.0
1.066CysTyr: 1.066 ± 0.573
0.0CysXaa: 0.0 ± 0.0
Asp
12.793AspAla: 12.793 ± 10.562
2.132AspCys: 2.132 ± 2.828
4.264AspAsp: 4.264 ± 1.921
3.198AspGlu: 3.198 ± 2.274
6.397AspPhe: 6.397 ± 1.769
8.529AspGly: 8.529 ± 7.512
3.198AspHis: 3.198 ± 2.348
1.066AspIle: 1.066 ± 0.573
0.0AspLys: 0.0 ± 0.0
4.264AspLeu: 4.264 ± 1.921
1.066AspMet: 1.066 ± 0.573
2.132AspAsn: 2.132 ± 1.147
1.066AspPro: 1.066 ± 0.573
4.264AspGln: 4.264 ± 2.294
6.397AspArg: 6.397 ± 2.096
2.132AspSer: 2.132 ± 2.765
8.529AspThr: 8.529 ± 2.867
0.0AspVal: 0.0 ± 0.0
0.0AspTrp: 0.0 ± 0.0
2.132AspTyr: 2.132 ± 1.147
0.0AspXaa: 0.0 ± 0.0
Glu
5.33GluAla: 5.33 ± 5.167
1.066GluCys: 1.066 ± 1.382
3.198GluAsp: 3.198 ± 2.348
5.33GluGlu: 5.33 ± 1.588
2.132GluPhe: 2.132 ± 1.147
5.33GluGly: 5.33 ± 1.483
3.198GluHis: 3.198 ± 2.348
0.0GluIle: 0.0 ± 0.0
4.264GluLys: 4.264 ± 0.817
3.198GluLeu: 3.198 ± 1.72
3.198GluMet: 3.198 ± 0.652
1.066GluAsn: 1.066 ± 0.573
2.132GluPro: 2.132 ± 0.916
1.066GluGln: 1.066 ± 0.573
3.198GluArg: 3.198 ± 3.752
4.264GluSer: 4.264 ± 0.817
5.33GluThr: 5.33 ± 2.867
3.198GluVal: 3.198 ± 0.652
3.198GluTrp: 3.198 ± 2.274
2.132GluTyr: 2.132 ± 1.147
0.0GluXaa: 0.0 ± 0.0
Phe
3.198PheAla: 3.198 ± 1.72
2.132PheCys: 2.132 ± 1.147
1.066PheAsp: 1.066 ± 0.573
0.0PheGlu: 0.0 ± 0.0
0.0PhePhe: 0.0 ± 0.0
5.33PheGly: 5.33 ± 2.867
0.0PheHis: 0.0 ± 0.0
2.132PheIle: 2.132 ± 0.916
2.132PheLys: 2.132 ± 1.147
1.066PheLeu: 1.066 ± 0.573
1.066PheMet: 1.066 ± 0.573
2.132PheAsn: 2.132 ± 1.147
0.0PhePro: 0.0 ± 0.0
4.264PheGln: 4.264 ± 2.294
1.066PheArg: 1.066 ± 0.573
2.132PheSer: 2.132 ± 0.916
1.066PheThr: 1.066 ± 0.573
0.0PheVal: 0.0 ± 0.0
1.066PheTrp: 1.066 ± 0.573
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
1.066GlyAla: 1.066 ± 0.573
2.132GlyCys: 2.132 ± 0.916
9.595GlyAsp: 9.595 ± 3.478
7.463GlyGlu: 7.463 ± 1.469
0.0GlyPhe: 0.0 ± 0.0
6.397GlyGly: 6.397 ± 1.769
2.132GlyHis: 2.132 ± 1.147
2.132GlyIle: 2.132 ± 1.147
1.066GlyLys: 1.066 ± 0.573
3.198GlyLeu: 3.198 ± 1.72
2.132GlyMet: 2.132 ± 1.147
3.198GlyAsn: 3.198 ± 2.348
2.132GlyPro: 2.132 ± 0.916
2.132GlyGln: 2.132 ± 1.147
3.198GlyArg: 3.198 ± 1.72
4.264GlySer: 4.264 ± 0.817
3.198GlyThr: 3.198 ± 0.652
1.066GlyVal: 1.066 ± 1.382
6.397GlyTrp: 6.397 ± 3.983
1.066GlyTyr: 1.066 ± 0.573
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
3.198HisAsp: 3.198 ± 2.348
1.066HisGlu: 1.066 ± 0.573
1.066HisPhe: 1.066 ± 1.382
0.0HisGly: 0.0 ± 0.0
1.066HisHis: 1.066 ± 0.573
0.0HisIle: 0.0 ± 0.0
1.066HisLys: 1.066 ± 0.573
3.198HisLeu: 3.198 ± 2.348
0.0HisMet: 0.0 ± 0.538
0.0HisAsn: 0.0 ± 0.0
2.132HisPro: 2.132 ± 0.916
2.132HisGln: 2.132 ± 2.765
2.132HisArg: 2.132 ± 0.916
1.066HisSer: 1.066 ± 0.573
1.066HisThr: 1.066 ± 1.382
0.0HisVal: 0.0 ± 0.0
2.132HisTrp: 2.132 ± 2.828
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.066IleAla: 1.066 ± 0.573
0.0IleCys: 0.0 ± 0.0
5.33IleAsp: 5.33 ± 1.253
3.198IleGlu: 3.198 ± 2.348
1.066IlePhe: 1.066 ± 0.573
3.198IleGly: 3.198 ± 2.348
2.132IleHis: 2.132 ± 2.765
2.132IleIle: 2.132 ± 1.147
2.132IleLys: 2.132 ± 0.916
2.132IleLeu: 2.132 ± 0.916
0.0IleMet: 0.0 ± 0.0
1.066IleAsn: 1.066 ± 0.573
2.132IlePro: 2.132 ± 0.916
1.066IleGln: 1.066 ± 0.573
4.264IleArg: 4.264 ± 2.294
1.066IleSer: 1.066 ± 0.573
3.198IleThr: 3.198 ± 1.72
1.066IleVal: 1.066 ± 0.573
0.0IleTrp: 0.0 ± 0.0
2.132IleTyr: 2.132 ± 1.147
0.0IleXaa: 0.0 ± 0.0
Lys
4.264LysAla: 4.264 ± 1.832
0.0LysCys: 0.0 ± 0.0
1.066LysAsp: 1.066 ± 0.573
5.33LysGlu: 5.33 ± 1.483
2.132LysPhe: 2.132 ± 1.147
8.529LysGly: 8.529 ± 1.722
0.0LysHis: 0.0 ± 0.0
2.132LysIle: 2.132 ± 1.147
6.397LysLys: 6.397 ± 1.303
2.132LysLeu: 2.132 ± 1.147
0.0LysMet: 0.0 ± 0.0
1.066LysAsn: 1.066 ± 0.573
3.198LysPro: 3.198 ± 2.274
5.33LysGln: 5.33 ± 3.179
8.529LysArg: 8.529 ± 2.099
2.132LysSer: 2.132 ± 1.147
2.132LysThr: 2.132 ± 1.147
5.33LysVal: 5.33 ± 1.253
0.0LysTrp: 0.0 ± 0.0
2.132LysTyr: 2.132 ± 1.147
0.0LysXaa: 0.0 ± 0.0
Leu
6.397LeuAla: 6.397 ± 5.961
1.066LeuCys: 1.066 ± 1.382
3.198LeuAsp: 3.198 ± 2.348
5.33LeuGlu: 5.33 ± 1.588
2.132LeuPhe: 2.132 ± 1.147
0.0LeuGly: 0.0 ± 0.0
2.132LeuHis: 2.132 ± 0.916
3.198LeuIle: 3.198 ± 0.652
3.198LeuLys: 3.198 ± 0.652
8.529LeuLeu: 8.529 ± 6.384
2.132LeuMet: 2.132 ± 0.916
2.132LeuAsn: 2.132 ± 0.916
4.264LeuPro: 4.264 ± 1.832
4.264LeuGln: 4.264 ± 2.294
5.33LeuArg: 5.33 ± 2.867
1.066LeuSer: 1.066 ± 0.573
4.264LeuThr: 4.264 ± 0.817
5.33LeuVal: 5.33 ± 2.867
5.33LeuTrp: 5.33 ± 1.588
3.198LeuTyr: 3.198 ± 1.72
0.0LeuXaa: 0.0 ± 0.0
Met
2.132MetAla: 2.132 ± 1.147
0.0MetCys: 0.0 ± 0.0
5.33MetAsp: 5.33 ± 2.639
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
2.132MetLys: 2.132 ± 0.916
1.066MetLeu: 1.066 ± 0.573
3.198MetMet: 3.198 ± 0.652
1.066MetAsn: 1.066 ± 0.573
2.132MetPro: 2.132 ± 2.828
2.132MetGln: 2.132 ± 1.147
1.066MetArg: 1.066 ± 0.573
0.0MetSer: 0.0 ± 0.0
1.066MetThr: 1.066 ± 0.573
1.066MetVal: 1.066 ± 0.573
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.066AsnAla: 1.066 ± 0.573
0.0AsnCys: 0.0 ± 0.0
2.132AsnAsp: 2.132 ± 1.147
1.066AsnGlu: 1.066 ± 0.573
0.0AsnPhe: 0.0 ± 0.0
2.132AsnGly: 2.132 ± 1.147
0.0AsnHis: 0.0 ± 0.0
2.132AsnIle: 2.132 ± 1.147
2.132AsnLys: 2.132 ± 0.916
2.132AsnLeu: 2.132 ± 1.147
0.0AsnMet: 0.0 ± 0.0
1.066AsnAsn: 1.066 ± 0.573
3.198AsnPro: 3.198 ± 1.72
1.066AsnGln: 1.066 ± 0.573
1.066AsnArg: 1.066 ± 0.573
2.132AsnSer: 2.132 ± 0.916
3.198AsnThr: 3.198 ± 0.652
0.0AsnVal: 0.0 ± 0.0
3.198AsnTrp: 3.198 ± 2.348
2.132AsnTyr: 2.132 ± 1.147
0.0AsnXaa: 0.0 ± 0.0
Pro
2.132ProAla: 2.132 ± 0.916
1.066ProCys: 1.066 ± 0.573
0.0ProAsp: 0.0 ± 0.0
4.264ProGlu: 4.264 ± 4.896
3.198ProPhe: 3.198 ± 1.72
1.066ProGly: 1.066 ± 1.382
2.132ProHis: 2.132 ± 1.147
4.264ProIle: 4.264 ± 1.832
6.397ProLys: 6.397 ± 1.769
5.33ProLeu: 5.33 ± 1.253
0.0ProMet: 0.0 ± 0.0
2.132ProAsn: 2.132 ± 0.916
4.264ProPro: 4.264 ± 2.294
2.132ProGln: 2.132 ± 1.147
4.264ProArg: 4.264 ± 3.65
3.198ProSer: 3.198 ± 0.652
4.264ProThr: 4.264 ± 2.294
2.132ProVal: 2.132 ± 0.916
0.0ProTrp: 0.0 ± 0.0
1.066ProTyr: 1.066 ± 0.573
0.0ProXaa: 0.0 ± 0.0
Gln
1.066GlnAla: 1.066 ± 0.573
1.066GlnCys: 1.066 ± 0.573
5.33GlnAsp: 5.33 ± 1.588
5.33GlnGlu: 5.33 ± 1.253
2.132GlnPhe: 2.132 ± 1.147
3.198GlnGly: 3.198 ± 1.72
0.0GlnHis: 0.0 ± 0.0
2.132GlnIle: 2.132 ± 0.916
4.264GlnLys: 4.264 ± 0.817
3.198GlnLeu: 3.198 ± 1.72
0.0GlnMet: 0.0 ± 0.0
1.066GlnAsn: 1.066 ± 0.573
3.198GlnPro: 3.198 ± 0.652
1.066GlnGln: 1.066 ± 1.382
4.264GlnArg: 4.264 ± 1.832
4.264GlnSer: 4.264 ± 0.817
2.132GlnThr: 2.132 ± 0.916
1.066GlnVal: 1.066 ± 1.382
3.198GlnTrp: 3.198 ± 1.72
2.132GlnTyr: 2.132 ± 1.147
0.0GlnXaa: 0.0 ± 0.0
Arg
4.264ArgAla: 4.264 ± 2.294
3.198ArgCys: 3.198 ± 3.752
5.33ArgAsp: 5.33 ± 1.588
1.066ArgGlu: 1.066 ± 0.573
2.132ArgPhe: 2.132 ± 1.147
3.198ArgGly: 3.198 ± 1.72
1.066ArgHis: 1.066 ± 1.382
1.066ArgIle: 1.066 ± 0.573
12.793ArgLys: 12.793 ± 5.496
4.264ArgLeu: 4.264 ± 0.817
3.198ArgMet: 3.198 ± 0.773
3.198ArgAsn: 3.198 ± 1.72
5.33ArgPro: 5.33 ± 1.253
5.33ArgGln: 5.33 ± 1.483
28.785ArgArg: 28.785 ± 13.704
2.132ArgSer: 2.132 ± 0.916
3.198ArgThr: 3.198 ± 1.72
5.33ArgVal: 5.33 ± 2.639
5.33ArgTrp: 5.33 ± 2.867
7.463ArgTyr: 7.463 ± 4.014
0.0ArgXaa: 0.0 ± 0.0
Ser
5.33SerAla: 5.33 ± 1.253
0.0SerCys: 0.0 ± 0.0
7.463SerAsp: 7.463 ± 5.923
2.132SerGlu: 2.132 ± 2.765
0.0SerPhe: 0.0 ± 0.0
3.198SerGly: 3.198 ± 1.72
1.066SerHis: 1.066 ± 1.382
2.132SerIle: 2.132 ± 1.147
1.066SerLys: 1.066 ± 0.573
3.198SerLeu: 3.198 ± 2.274
0.0SerMet: 0.0 ± 0.0
0.0SerAsn: 0.0 ± 0.0
3.198SerPro: 3.198 ± 0.652
2.132SerGln: 2.132 ± 0.916
5.33SerArg: 5.33 ± 1.483
9.595SerSer: 9.595 ± 3.428
2.132SerThr: 2.132 ± 1.147
4.264SerVal: 4.264 ± 0.817
2.132SerTrp: 2.132 ± 1.147
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.264ThrAla: 4.264 ± 1.921
0.0ThrCys: 0.0 ± 0.0
6.397ThrAsp: 6.397 ± 2.096
7.463ThrGlu: 7.463 ± 4.014
0.0ThrPhe: 0.0 ± 0.0
1.066ThrGly: 1.066 ± 0.573
1.066ThrHis: 1.066 ± 0.573
4.264ThrIle: 4.264 ± 1.921
3.198ThrLys: 3.198 ± 2.348
5.33ThrLeu: 5.33 ± 2.867
0.0ThrMet: 0.0 ± 0.0
3.198ThrAsn: 3.198 ± 1.72
5.33ThrPro: 5.33 ± 1.483
2.132ThrGln: 2.132 ± 1.147
4.264ThrArg: 4.264 ± 0.817
3.198ThrSer: 3.198 ± 2.274
5.33ThrThr: 5.33 ± 2.639
2.132ThrVal: 2.132 ± 0.916
2.132ThrTrp: 2.132 ± 1.147
1.066ThrTyr: 1.066 ± 0.573
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
1.066ValCys: 1.066 ± 0.573
3.198ValAsp: 3.198 ± 2.348
0.0ValGlu: 0.0 ± 0.0
1.066ValPhe: 1.066 ± 0.573
1.066ValGly: 1.066 ± 1.382
1.066ValHis: 1.066 ± 1.382
2.132ValIle: 2.132 ± 1.147
2.132ValLys: 2.132 ± 1.147
3.198ValLeu: 3.198 ± 0.652
2.132ValMet: 2.132 ± 1.147
1.066ValAsn: 1.066 ± 1.382
3.198ValPro: 3.198 ± 0.652
2.132ValGln: 2.132 ± 0.916
4.264ValArg: 4.264 ± 2.294
4.264ValSer: 4.264 ± 3.65
4.264ValThr: 4.264 ± 1.921
1.066ValVal: 1.066 ± 0.573
0.0ValTrp: 0.0 ± 0.0
2.132ValTyr: 2.132 ± 1.147
0.0ValXaa: 0.0 ± 0.0
Trp
1.066TrpAla: 1.066 ± 0.573
0.0TrpCys: 0.0 ± 0.0
2.132TrpAsp: 2.132 ± 1.147
3.198TrpGlu: 3.198 ± 2.348
2.132TrpPhe: 2.132 ± 1.147
4.264TrpGly: 4.264 ± 2.294
2.132TrpHis: 2.132 ± 2.828
0.0TrpIle: 0.0 ± 0.0
3.198TrpLys: 3.198 ± 1.72
6.397TrpLeu: 6.397 ± 4.697
1.066TrpMet: 1.066 ± 1.673
1.066TrpAsn: 1.066 ± 0.573
1.066TrpPro: 1.066 ± 0.573
3.198TrpGln: 3.198 ± 2.348
5.33TrpArg: 5.33 ± 2.867
2.132TrpSer: 2.132 ± 0.916
1.066TrpThr: 1.066 ± 1.382
0.0TrpVal: 0.0 ± 0.0
3.198TrpTrp: 3.198 ± 1.72
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.066TyrAla: 1.066 ± 0.573
1.066TyrCys: 1.066 ± 0.573
0.0TyrAsp: 0.0 ± 0.0
1.066TyrGlu: 1.066 ± 0.573
1.066TyrPhe: 1.066 ± 0.573
3.198TyrGly: 3.198 ± 1.72
0.0TyrHis: 0.0 ± 0.0
1.066TyrIle: 1.066 ± 0.573
1.066TyrLys: 1.066 ± 0.573
2.132TyrLeu: 2.132 ± 1.147
0.0TyrMet: 0.0 ± 0.0
2.132TyrAsn: 2.132 ± 1.147
3.198TyrPro: 3.198 ± 1.72
2.132TyrGln: 2.132 ± 1.147
7.463TyrArg: 7.463 ± 4.014
1.066TyrSer: 1.066 ± 0.573
0.0TyrThr: 0.0 ± 0.0
1.066TyrVal: 1.066 ± 0.573
2.132TyrTrp: 2.132 ± 1.147
3.198TyrTyr: 3.198 ± 1.72
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (939 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski