Amino acid dipepetide frequency for Barley virus G

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.419AlaAla: 6.419 ± 1.075
1.689AlaCys: 1.689 ± 0.904
3.378AlaAsp: 3.378 ± 1.073
3.378AlaGlu: 3.378 ± 1.46
3.041AlaPhe: 3.041 ± 0.411
3.378AlaGly: 3.378 ± 0.978
2.365AlaHis: 2.365 ± 0.772
2.703AlaIle: 2.703 ± 0.4
3.041AlaLys: 3.041 ± 1.04
8.784AlaLeu: 8.784 ± 1.978
1.351AlaMet: 1.351 ± 0.477
2.703AlaAsn: 2.703 ± 0.691
5.068AlaPro: 5.068 ± 1.714
1.689AlaGln: 1.689 ± 0.625
4.054AlaArg: 4.054 ± 1.017
8.108AlaSer: 8.108 ± 2.096
1.689AlaThr: 1.689 ± 0.495
2.027AlaVal: 2.027 ± 0.417
0.338AlaTrp: 0.338 ± 0.485
3.378AlaTyr: 3.378 ± 0.762
0.0AlaXaa: 0.0 ± 0.0
Cys
2.027CysAla: 2.027 ± 0.941
1.351CysCys: 1.351 ± 0.598
0.338CysAsp: 0.338 ± 0.238
1.014CysGlu: 1.014 ± 0.236
0.676CysPhe: 0.676 ± 0.299
1.351CysGly: 1.351 ± 0.953
0.0CysHis: 0.0 ± 0.0
0.338CysIle: 0.338 ± 0.238
0.676CysLys: 0.676 ± 0.299
1.689CysLeu: 1.689 ± 0.747
0.338CysMet: 0.338 ± 0.238
0.0CysAsn: 0.0 ± 0.0
0.338CysPro: 0.338 ± 0.238
1.014CysGln: 1.014 ± 0.467
0.338CysArg: 0.338 ± 0.485
2.027CysSer: 2.027 ± 0.767
1.014CysThr: 1.014 ± 0.236
1.351CysVal: 1.351 ± 0.416
0.338CysTrp: 0.338 ± 0.238
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.081AspAla: 6.081 ± 0.809
0.338AspCys: 0.338 ± 0.238
4.73AspAsp: 4.73 ± 0.937
2.703AspGlu: 2.703 ± 0.693
2.027AspPhe: 2.027 ± 1.314
2.703AspGly: 2.703 ± 0.536
0.338AspHis: 0.338 ± 0.275
2.365AspIle: 2.365 ± 0.53
0.338AspLys: 0.338 ± 0.275
3.378AspLeu: 3.378 ± 1.769
1.351AspMet: 1.351 ± 0.737
0.676AspAsn: 0.676 ± 0.971
3.378AspPro: 3.378 ± 0.279
2.027AspGln: 2.027 ± 0.725
1.689AspArg: 1.689 ± 0.871
4.73AspSer: 4.73 ± 1.046
1.014AspThr: 1.014 ± 0.467
5.405AspVal: 5.405 ± 0.643
0.676AspTrp: 0.676 ± 0.476
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
5.405GluAla: 5.405 ± 0.888
1.014GluCys: 1.014 ± 0.679
4.054GluAsp: 4.054 ± 1.094
2.365GluGlu: 2.365 ± 0.454
4.392GluPhe: 4.392 ± 1.834
4.392GluGly: 4.392 ± 0.604
0.0GluHis: 0.0 ± 0.0
2.365GluIle: 2.365 ± 0.774
2.365GluLys: 2.365 ± 0.651
7.095GluLeu: 7.095 ± 0.399
0.0GluMet: 0.0 ± 0.0
1.014GluAsn: 1.014 ± 0.609
2.027GluPro: 2.027 ± 0.638
2.703GluGln: 2.703 ± 0.712
2.365GluArg: 2.365 ± 0.742
5.068GluSer: 5.068 ± 0.596
3.041GluThr: 3.041 ± 1.099
3.041GluVal: 3.041 ± 1.174
1.014GluTrp: 1.014 ± 0.416
1.351GluTyr: 1.351 ± 0.87
0.0GluXaa: 0.0 ± 0.0
Phe
1.689PheAla: 1.689 ± 0.697
1.689PheCys: 1.689 ± 0.793
3.378PheAsp: 3.378 ± 0.81
2.703PheGlu: 2.703 ± 1.21
0.676PhePhe: 0.676 ± 0.971
3.378PheGly: 3.378 ± 0.393
0.0PheHis: 0.0 ± 0.0
2.703PheIle: 2.703 ± 1.208
2.365PheLys: 2.365 ± 1.141
3.716PheLeu: 3.716 ± 0.9
0.0PheMet: 0.0 ± 0.292
1.689PheAsn: 1.689 ± 0.503
1.351PhePro: 1.351 ± 0.832
1.689PheGln: 1.689 ± 0.304
3.041PheArg: 3.041 ± 1.234
3.716PheSer: 3.716 ± 1.815
3.378PheThr: 3.378 ± 0.279
3.378PheVal: 3.378 ± 1.155
0.338PheTrp: 0.338 ± 0.485
0.338PheTyr: 0.338 ± 0.275
0.0PheXaa: 0.0 ± 0.0
Gly
2.027GlyAla: 2.027 ± 0.811
2.703GlyCys: 2.703 ± 0.623
1.014GlyAsp: 1.014 ± 0.467
2.703GlyGlu: 2.703 ± 0.389
3.041GlyPhe: 3.041 ± 1.141
9.459GlyGly: 9.459 ± 2.39
0.676GlyHis: 0.676 ± 0.299
2.365GlyIle: 2.365 ± 1.318
4.392GlyLys: 4.392 ± 1.5
2.703GlyLeu: 2.703 ± 0.953
0.338GlyMet: 0.338 ± 0.275
4.392GlyAsn: 4.392 ± 1.291
2.365GlyPro: 2.365 ± 0.53
2.027GlyGln: 2.027 ± 1.014
6.081GlyArg: 6.081 ± 1.653
6.757GlySer: 6.757 ± 2.163
5.405GlyThr: 5.405 ± 1.988
4.054GlyVal: 4.054 ± 0.844
2.365GlyTrp: 2.365 ± 0.774
3.041GlyTyr: 3.041 ± 0.77
0.0GlyXaa: 0.0 ± 0.0
His
0.676HisAla: 0.676 ± 0.971
0.338HisCys: 0.338 ± 0.238
0.676HisAsp: 0.676 ± 0.26
0.676HisGlu: 0.676 ± 0.507
0.338HisPhe: 0.338 ± 0.485
0.676HisGly: 0.676 ± 0.299
0.0HisHis: 0.0 ± 0.0
0.338HisIle: 0.338 ± 0.485
0.676HisLys: 0.676 ± 0.476
0.676HisLeu: 0.676 ± 0.632
0.0HisMet: 0.0 ± 0.0
2.365HisAsn: 2.365 ± 0.993
1.014HisPro: 1.014 ± 0.459
0.338HisGln: 0.338 ± 0.485
2.027HisArg: 2.027 ± 0.592
0.676HisSer: 0.676 ± 0.632
0.676HisThr: 0.676 ± 0.36
2.027HisVal: 2.027 ± 0.592
0.676HisTrp: 0.676 ± 0.299
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.378IleAla: 3.378 ± 1.081
0.676IleCys: 0.676 ± 0.299
1.689IleAsp: 1.689 ± 0.514
2.027IleGlu: 2.027 ± 0.386
2.027IlePhe: 2.027 ± 0.896
1.351IleGly: 1.351 ± 0.413
1.014IleHis: 1.014 ± 1.078
0.676IleIle: 0.676 ± 0.299
2.365IleLys: 2.365 ± 0.442
6.081IleLeu: 6.081 ± 1.564
0.338IleMet: 0.338 ± 0.238
1.689IleAsn: 1.689 ± 0.961
4.392IlePro: 4.392 ± 1.233
1.689IleGln: 1.689 ± 0.304
2.027IleArg: 2.027 ± 0.546
5.405IleSer: 5.405 ± 0.727
2.365IleThr: 2.365 ± 0.353
2.027IleVal: 2.027 ± 0.625
0.676IleTrp: 0.676 ± 0.299
1.689IleTyr: 1.689 ± 0.304
0.0IleXaa: 0.0 ± 0.0
Lys
4.054LysAla: 4.054 ± 0.551
0.338LysCys: 0.338 ± 0.238
2.703LysAsp: 2.703 ± 1.208
2.365LysGlu: 2.365 ± 0.76
2.027LysPhe: 2.027 ± 0.412
3.378LysGly: 3.378 ± 1.064
2.365LysHis: 2.365 ± 0.849
5.405LysIle: 5.405 ± 1.302
1.689LysLys: 1.689 ± 0.689
4.054LysLeu: 4.054 ± 0.602
1.689LysMet: 1.689 ± 0.471
1.351LysAsn: 1.351 ± 0.437
2.365LysPro: 2.365 ± 0.648
2.365LysGln: 2.365 ± 1.315
3.041LysArg: 3.041 ± 0.545
4.73LysSer: 4.73 ± 0.736
2.027LysThr: 2.027 ± 0.592
3.041LysVal: 3.041 ± 0.831
0.0LysTrp: 0.0 ± 0.0
0.676LysTyr: 0.676 ± 0.299
0.338LysXaa: 0.338 ± 0.275
Leu
5.405LeuAla: 5.405 ± 2.134
2.703LeuCys: 2.703 ± 1.21
2.703LeuAsp: 2.703 ± 0.618
4.392LeuGlu: 4.392 ± 1.883
5.068LeuPhe: 5.068 ± 1.476
4.054LeuGly: 4.054 ± 0.863
0.338LeuHis: 0.338 ± 0.238
5.405LeuIle: 5.405 ± 1.387
4.73LeuLys: 4.73 ± 0.714
7.432LeuLeu: 7.432 ± 3.011
4.054LeuMet: 4.054 ± 1.21
3.041LeuAsn: 3.041 ± 0.77
3.716LeuPro: 3.716 ± 0.864
5.743LeuGln: 5.743 ± 1.452
5.068LeuArg: 5.068 ± 1.135
9.459LeuSer: 9.459 ± 0.745
9.122LeuThr: 9.122 ± 1.22
4.73LeuVal: 4.73 ± 1.549
1.689LeuTrp: 1.689 ± 0.674
4.73LeuTyr: 4.73 ± 1.125
0.0LeuXaa: 0.0 ± 0.0
Met
2.365MetAla: 2.365 ± 1.141
0.0MetCys: 0.0 ± 0.0
1.014MetAsp: 1.014 ± 0.61
0.676MetGlu: 0.676 ± 0.36
0.338MetPhe: 0.338 ± 0.329
0.338MetGly: 0.338 ± 0.238
0.338MetHis: 0.338 ± 0.485
0.676MetIle: 0.676 ± 0.26
0.676MetLys: 0.676 ± 0.324
2.027MetLeu: 2.027 ± 0.599
0.0MetMet: 0.0 ± 0.0
1.689MetAsn: 1.689 ± 0.515
1.014MetPro: 1.014 ± 0.366
0.676MetGln: 0.676 ± 0.299
1.689MetArg: 1.689 ± 0.503
2.027MetSer: 2.027 ± 0.778
0.676MetThr: 0.676 ± 0.26
0.338MetVal: 0.338 ± 0.275
0.0MetTrp: 0.0 ± 0.0
0.338MetTyr: 0.338 ± 0.275
0.0MetXaa: 0.0 ± 0.0
Asn
2.703AsnAla: 2.703 ± 0.4
0.338AsnCys: 0.338 ± 0.238
2.703AsnAsp: 2.703 ± 0.498
1.014AsnGlu: 1.014 ± 0.479
2.365AsnPhe: 2.365 ± 0.809
4.73AsnGly: 4.73 ± 0.715
0.338AsnHis: 0.338 ± 0.238
0.338AsnIle: 0.338 ± 0.485
5.068AsnLys: 5.068 ± 1.393
3.716AsnLeu: 3.716 ± 1.01
0.338AsnMet: 0.338 ± 0.245
3.041AsnAsn: 3.041 ± 0.445
2.027AsnPro: 2.027 ± 0.53
1.689AsnGln: 1.689 ± 0.472
1.014AsnArg: 1.014 ± 0.467
4.73AsnSer: 4.73 ± 0.529
3.378AsnThr: 3.378 ± 0.747
0.676AsnVal: 0.676 ± 0.26
1.351AsnTrp: 1.351 ± 0.598
0.676AsnTyr: 0.676 ± 0.55
0.0AsnXaa: 0.0 ± 0.0
Pro
5.405ProAla: 5.405 ± 1.999
0.0ProCys: 0.0 ± 0.0
1.689ProAsp: 1.689 ± 0.997
2.027ProGlu: 2.027 ± 1.361
0.676ProPhe: 0.676 ± 0.443
4.392ProGly: 4.392 ± 1.412
1.351ProHis: 1.351 ± 0.591
2.703ProIle: 2.703 ± 0.681
5.405ProLys: 5.405 ± 1.092
2.365ProLeu: 2.365 ± 0.737
0.0ProMet: 0.0 ± 0.0
1.689ProAsn: 1.689 ± 0.963
6.757ProPro: 6.757 ± 1.924
4.054ProGln: 4.054 ± 1.072
3.041ProArg: 3.041 ± 1.029
6.081ProSer: 6.081 ± 1.528
5.068ProThr: 5.068 ± 1.469
2.365ProVal: 2.365 ± 0.73
0.0ProTrp: 0.0 ± 0.0
1.689ProTyr: 1.689 ± 0.304
0.0ProXaa: 0.0 ± 0.0
Gln
3.716GlnAla: 3.716 ± 0.637
1.014GlnCys: 1.014 ± 0.416
1.689GlnAsp: 1.689 ± 0.937
3.378GlnGlu: 3.378 ± 1.262
2.027GlnPhe: 2.027 ± 0.412
3.041GlnGly: 3.041 ± 0.798
1.014GlnHis: 1.014 ± 0.366
1.689GlnIle: 1.689 ± 0.578
2.703GlnLys: 2.703 ± 0.737
3.378GlnLeu: 3.378 ± 0.977
0.338GlnMet: 0.338 ± 0.238
6.081GlnAsn: 6.081 ± 1.645
3.041GlnPro: 3.041 ± 1.067
3.041GlnGln: 3.041 ± 0.716
3.716GlnArg: 3.716 ± 0.692
2.365GlnSer: 2.365 ± 1.047
1.014GlnThr: 1.014 ± 0.416
1.351GlnVal: 1.351 ± 0.849
1.014GlnTrp: 1.014 ± 0.37
1.351GlnTyr: 1.351 ± 0.353
0.0GlnXaa: 0.0 ± 0.0
Arg
3.378ArgAla: 3.378 ± 0.771
0.338ArgCys: 0.338 ± 0.485
2.027ArgAsp: 2.027 ± 0.625
5.068ArgGlu: 5.068 ± 0.912
1.014ArgPhe: 1.014 ± 0.394
4.392ArgGly: 4.392 ± 0.652
1.351ArgHis: 1.351 ± 1.374
1.689ArgIle: 1.689 ± 0.304
1.351ArgLys: 1.351 ± 0.346
8.784ArgLeu: 8.784 ± 2.097
1.351ArgMet: 1.351 ± 0.346
2.365ArgAsn: 2.365 ± 0.593
4.73ArgPro: 4.73 ± 1.363
0.676ArgGln: 0.676 ± 0.425
12.5ArgArg: 12.5 ± 4.535
5.743ArgSer: 5.743 ± 2.007
6.081ArgThr: 6.081 ± 2.013
5.068ArgVal: 5.068 ± 1.158
1.351ArgTrp: 1.351 ± 0.477
3.716ArgTyr: 3.716 ± 1.386
0.0ArgXaa: 0.0 ± 0.0
Ser
5.405SerAla: 5.405 ± 0.793
1.351SerCys: 1.351 ± 0.598
4.392SerAsp: 4.392 ± 2.225
5.405SerGlu: 5.405 ± 2.114
3.041SerPhe: 3.041 ± 2.077
6.757SerGly: 6.757 ± 2.025
0.338SerHis: 0.338 ± 0.238
6.757SerIle: 6.757 ± 1.145
5.068SerLys: 5.068 ± 0.858
11.824SerLeu: 11.824 ± 0.8
0.338SerMet: 0.338 ± 0.253
4.054SerAsn: 4.054 ± 0.947
5.405SerPro: 5.405 ± 1.23
3.378SerGln: 3.378 ± 0.774
8.446SerArg: 8.446 ± 1.985
11.824SerSer: 11.824 ± 2.086
6.081SerThr: 6.081 ± 1.035
8.108SerVal: 8.108 ± 1.42
0.676SerTrp: 0.676 ± 0.55
3.378SerTyr: 3.378 ± 0.471
0.0SerXaa: 0.0 ± 0.0
Thr
1.689ThrAla: 1.689 ± 0.545
0.338ThrCys: 0.338 ± 0.238
3.378ThrAsp: 3.378 ± 0.922
3.041ThrGlu: 3.041 ± 0.64
4.392ThrPhe: 4.392 ± 1.291
5.068ThrGly: 5.068 ± 1.891
0.676ThrHis: 0.676 ± 0.26
2.365ThrIle: 2.365 ± 0.993
1.014ThrLys: 1.014 ± 0.467
7.095ThrLeu: 7.095 ± 0.951
1.689ThrMet: 1.689 ± 0.472
2.027ThrAsn: 2.027 ± 0.517
4.73ThrPro: 4.73 ± 1.426
4.73ThrGln: 4.73 ± 0.939
4.392ThrArg: 4.392 ± 0.227
6.081ThrSer: 6.081 ± 1.036
3.041ThrThr: 3.041 ± 1.132
2.027ThrVal: 2.027 ± 0.615
1.014ThrTrp: 1.014 ± 0.467
1.351ThrTyr: 1.351 ± 0.416
0.0ThrXaa: 0.0 ± 0.0
Val
4.392ValAla: 4.392 ± 0.527
0.0ValCys: 0.0 ± 0.0
2.365ValAsp: 2.365 ± 0.382
5.743ValGlu: 5.743 ± 1.204
2.027ValPhe: 2.027 ± 0.471
3.041ValGly: 3.041 ± 0.881
1.014ValHis: 1.014 ± 0.394
1.014ValIle: 1.014 ± 0.52
2.365ValLys: 2.365 ± 0.593
5.405ValLeu: 5.405 ± 0.803
1.351ValMet: 1.351 ± 0.598
1.351ValAsn: 1.351 ± 0.346
1.689ValPro: 1.689 ± 0.415
4.392ValGln: 4.392 ± 0.815
4.73ValArg: 4.73 ± 0.72
6.419ValSer: 6.419 ± 0.809
2.703ValThr: 2.703 ± 1.423
4.392ValVal: 4.392 ± 1.983
1.014ValTrp: 1.014 ± 0.392
2.365ValTyr: 2.365 ± 0.608
0.0ValXaa: 0.0 ± 0.0
Trp
1.351TrpAla: 1.351 ± 0.346
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.351TrpGlu: 1.351 ± 0.679
0.0TrpPhe: 0.0 ± 0.0
1.351TrpGly: 1.351 ± 0.346
0.338TrpHis: 0.338 ± 0.275
0.338TrpIle: 0.338 ± 0.238
0.676TrpLys: 0.676 ± 0.299
1.689TrpLeu: 1.689 ± 0.625
1.351TrpMet: 1.351 ± 0.477
0.0TrpAsn: 0.0 ± 0.0
1.014TrpPro: 1.014 ± 0.467
1.014TrpGln: 1.014 ± 0.236
1.351TrpArg: 1.351 ± 0.591
3.378TrpSer: 3.378 ± 0.552
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.014TyrAla: 1.014 ± 0.394
0.0TyrCys: 0.0 ± 0.0
2.027TyrAsp: 2.027 ± 0.386
3.041TyrGlu: 3.041 ± 0.545
2.365TyrPhe: 2.365 ± 0.723
0.676TyrGly: 0.676 ± 0.26
1.014TyrHis: 1.014 ± 0.392
1.351TyrIle: 1.351 ± 0.353
3.041TyrLys: 3.041 ± 1.005
1.689TyrLeu: 1.689 ± 0.503
0.338TyrMet: 0.338 ± 0.485
1.014TyrAsn: 1.014 ± 0.416
0.338TyrPro: 0.338 ± 0.485
2.027TyrGln: 2.027 ± 0.71
2.365TyrArg: 2.365 ± 0.76
2.703TyrSer: 2.703 ± 0.623
2.365TyrThr: 2.365 ± 0.392
2.027TyrVal: 2.027 ± 0.675
0.676TyrTrp: 0.676 ± 0.55
1.689TyrTyr: 1.689 ± 0.415
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.338XaaVal: 0.338 ± 0.275
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2961 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski