Amino acid dipepetide frequency for Aphis glycines virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.33AlaAla: 9.33 ± 1.292
0.549AlaCys: 0.549 ± 0.313
1.098AlaAsp: 1.098 ± 0.626
2.744AlaGlu: 2.744 ± 0.504
1.647AlaPhe: 1.647 ± 0.436
9.879AlaGly: 9.879 ± 1.579
1.098AlaHis: 1.098 ± 0.409
3.293AlaIle: 3.293 ± 1.357
6.037AlaLys: 6.037 ± 0.967
8.782AlaLeu: 8.782 ± 1.517
3.293AlaMet: 3.293 ± 1.524
4.94AlaAsn: 4.94 ± 2.731
3.842AlaPro: 3.842 ± 1.049
2.744AlaGln: 2.744 ± 1.566
6.037AlaArg: 6.037 ± 1.801
3.293AlaSer: 3.293 ± 0.512
3.842AlaThr: 3.842 ± 1.049
6.037AlaVal: 6.037 ± 0.967
0.0AlaTrp: 0.0 ± 0.0
3.842AlaTyr: 3.842 ± 0.28
0.549AlaXaa: 0.549 ± 0.583
Cys
1.098CysAla: 1.098 ± 1.187
0.0CysCys: 0.0 ± 0.0
1.098CysAsp: 1.098 ± 1.187
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.098CysGly: 1.098 ± 0.626
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.098CysLeu: 1.098 ± 0.409
0.0CysMet: 0.0 ± 0.0
0.549CysAsn: 0.549 ± 0.313
0.549CysPro: 0.549 ± 0.313
0.0CysGln: 0.0 ± 0.0
0.549CysArg: 0.549 ± 0.313
1.098CysSer: 1.098 ± 0.626
0.0CysThr: 0.0 ± 0.0
0.549CysVal: 0.549 ± 0.583
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.842AspAla: 3.842 ± 0.28
1.098AspCys: 1.098 ± 0.626
3.842AspAsp: 3.842 ± 0.28
3.842AspGlu: 3.842 ± 0.682
3.842AspPhe: 3.842 ± 1.752
2.195AspGly: 2.195 ± 0.64
1.098AspHis: 1.098 ± 0.626
2.195AspIle: 2.195 ± 0.64
2.195AspLys: 2.195 ± 1.253
2.744AspLeu: 2.744 ± 1.566
1.098AspMet: 1.098 ± 0.409
1.098AspAsn: 1.098 ± 0.409
2.744AspPro: 2.744 ± 0.908
1.098AspGln: 1.098 ± 0.626
2.195AspArg: 2.195 ± 1.253
4.94AspSer: 4.94 ± 2.104
3.842AspThr: 3.842 ± 0.28
6.586AspVal: 6.586 ± 2.104
2.195AspTrp: 2.195 ± 0.666
3.293AspTyr: 3.293 ± 0.512
0.0AspXaa: 0.0 ± 0.0
Glu
6.037GluAla: 6.037 ± 2.728
0.0GluCys: 0.0 ± 0.0
2.744GluAsp: 2.744 ± 0.908
3.842GluGlu: 3.842 ± 0.682
1.647GluPhe: 1.647 ± 0.94
7.684GluGly: 7.684 ± 0.561
0.0GluHis: 0.0 ± 0.0
2.195GluIle: 2.195 ± 0.666
2.744GluLys: 2.744 ± 0.504
3.293GluLeu: 3.293 ± 1.199
3.293GluMet: 3.293 ± 2.36
1.098GluAsn: 1.098 ± 0.626
2.195GluPro: 2.195 ± 1.253
1.647GluGln: 1.647 ± 0.436
7.135GluArg: 7.135 ± 3.38
3.842GluSer: 3.842 ± 1.498
1.647GluThr: 1.647 ± 0.436
6.586GluVal: 6.586 ± 0.63
1.098GluTrp: 1.098 ± 0.409
1.098GluTyr: 1.098 ± 0.626
0.0GluXaa: 0.0 ± 0.0
Phe
1.098PheAla: 1.098 ± 0.626
0.0PheCys: 0.0 ± 0.0
1.647PheAsp: 1.647 ± 0.94
2.195PheGlu: 2.195 ± 1.208
0.0PhePhe: 0.0 ± 0.0
2.744PheGly: 2.744 ± 1.351
1.098PheHis: 1.098 ± 1.166
1.098PheIle: 1.098 ± 1.187
1.098PheLys: 1.098 ± 0.409
2.195PheLeu: 2.195 ± 1.253
1.647PheMet: 1.647 ± 0.94
2.195PheAsn: 2.195 ± 1.208
2.744PhePro: 2.744 ± 0.504
0.549PheGln: 0.549 ± 0.583
1.098PheArg: 1.098 ± 0.409
1.098PheSer: 1.098 ± 1.166
2.195PheThr: 2.195 ± 0.817
1.647PheVal: 1.647 ± 0.94
0.549PheTrp: 0.549 ± 0.313
0.549PheTyr: 0.549 ± 0.583
0.0PheXaa: 0.0 ± 0.0
Gly
6.037GlyAla: 6.037 ± 0.924
1.098GlyCys: 1.098 ± 1.187
3.293GlyAsp: 3.293 ± 1.199
6.586GlyGlu: 6.586 ± 1.023
2.744GlyPhe: 2.744 ± 0.896
3.842GlyGly: 3.842 ± 1.564
1.098GlyHis: 1.098 ± 0.626
3.293GlyIle: 3.293 ± 0.872
4.391GlyLys: 4.391 ± 2.506
6.037GlyLeu: 6.037 ± 3.021
2.195GlyMet: 2.195 ± 0.666
1.647GlyAsn: 1.647 ± 0.94
2.195GlyPro: 2.195 ± 1.253
2.195GlyGln: 2.195 ± 0.817
1.098GlyArg: 1.098 ± 0.409
2.195GlySer: 2.195 ± 2.375
5.488GlyThr: 5.488 ± 1.501
3.293GlyVal: 3.293 ± 1.879
0.549GlyTrp: 0.549 ± 0.313
3.293GlyTyr: 3.293 ± 1.199
0.0GlyXaa: 0.0 ± 0.0
His
2.195HisAla: 2.195 ± 1.253
0.549HisCys: 0.549 ± 0.583
1.098HisAsp: 1.098 ± 0.626
0.549HisGlu: 0.549 ± 0.313
1.098HisPhe: 1.098 ± 0.626
2.195HisGly: 2.195 ± 1.253
0.549HisHis: 0.549 ± 0.313
0.0HisIle: 0.0 ± 0.0
1.098HisLys: 1.098 ± 0.626
1.647HisLeu: 1.647 ± 0.957
1.647HisMet: 1.647 ± 0.91
0.549HisAsn: 0.549 ± 0.313
1.098HisPro: 1.098 ± 0.626
0.549HisGln: 0.549 ± 0.313
0.549HisArg: 0.549 ± 0.583
0.549HisSer: 0.549 ± 0.313
1.098HisThr: 1.098 ± 0.409
0.0HisVal: 0.0 ± 0.0
1.098HisTrp: 1.098 ± 1.187
0.549HisTyr: 0.549 ± 0.313
0.0HisXaa: 0.0 ± 0.0
Ile
3.293IleAla: 3.293 ± 0.585
0.549IleCys: 0.549 ± 0.313
2.744IleAsp: 2.744 ± 1.566
1.647IleGlu: 1.647 ± 0.94
0.0IlePhe: 0.0 ± 0.0
1.098IleGly: 1.098 ± 1.187
1.647IleHis: 1.647 ± 0.91
0.0IleIle: 0.0 ± 0.0
4.391IleLys: 4.391 ± 0.105
1.098IleLeu: 1.098 ± 1.166
0.549IleMet: 0.549 ± 0.313
2.744IleAsn: 2.744 ± 0.504
1.647IlePro: 1.647 ± 0.436
0.0IleGln: 0.0 ± 0.0
2.744IleArg: 2.744 ± 0.504
3.842IleSer: 3.842 ± 1.054
3.293IleThr: 3.293 ± 1.199
2.744IleVal: 2.744 ± 1.566
1.647IleTrp: 1.647 ± 0.91
1.647IleTyr: 1.647 ± 0.436
0.0IleXaa: 0.0 ± 0.0
Lys
5.488LysAla: 5.488 ± 0.306
1.647LysCys: 1.647 ± 0.91
0.549LysAsp: 0.549 ± 0.313
3.842LysGlu: 3.842 ± 2.193
2.195LysPhe: 2.195 ± 0.817
4.94LysGly: 4.94 ± 1.467
1.647LysHis: 1.647 ± 0.436
1.647LysIle: 1.647 ± 0.94
7.135LysLys: 7.135 ± 0.584
3.842LysLeu: 3.842 ± 2.193
2.744LysMet: 2.744 ± 0.504
2.195LysAsn: 2.195 ± 1.253
2.744LysPro: 2.744 ± 1.566
2.744LysGln: 2.744 ± 1.566
4.94LysArg: 4.94 ± 3.238
3.293LysSer: 3.293 ± 1.199
10.428LysThr: 10.428 ± 3.915
3.293LysVal: 3.293 ± 0.585
2.195LysTrp: 2.195 ± 0.666
0.549LysTyr: 0.549 ± 0.313
0.0LysXaa: 0.0 ± 0.0
Leu
8.782LeuAla: 8.782 ± 0.681
0.0LeuCys: 0.0 ± 0.0
3.842LeuAsp: 3.842 ± 1.049
4.94LeuGlu: 4.94 ± 2.11
3.842LeuPhe: 3.842 ± 1.049
4.94LeuGly: 4.94 ± 0.373
1.098LeuHis: 1.098 ± 0.409
3.842LeuIle: 3.842 ± 0.28
3.293LeuLys: 3.293 ± 1.357
7.135LeuLeu: 7.135 ± 1.904
2.195LeuMet: 2.195 ± 1.253
5.488LeuAsn: 5.488 ± 1.185
6.037LeuPro: 6.037 ± 0.924
1.647LeuGln: 1.647 ± 0.91
5.488LeuArg: 5.488 ± 0.681
4.94LeuSer: 4.94 ± 3.238
8.233LeuThr: 8.233 ± 3.421
5.488LeuVal: 5.488 ± 1.185
1.098LeuTrp: 1.098 ± 0.409
1.098LeuTyr: 1.098 ± 0.409
0.0LeuXaa: 0.0 ± 0.0
Met
2.195MetAla: 2.195 ± 1.253
1.098MetCys: 1.098 ± 0.626
4.391MetAsp: 4.391 ± 0.93
3.842MetGlu: 3.842 ± 2.058
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.549MetHis: 0.549 ± 0.313
1.098MetIle: 1.098 ± 0.626
1.098MetLys: 1.098 ± 0.409
4.391MetLeu: 4.391 ± 1.759
0.549MetMet: 0.549 ± 0.313
1.098MetAsn: 1.098 ± 0.626
1.647MetPro: 1.647 ± 0.94
0.549MetGln: 0.549 ± 0.313
3.293MetArg: 3.293 ± 1.199
1.098MetSer: 1.098 ± 1.187
2.195MetThr: 2.195 ± 0.666
2.744MetVal: 2.744 ± 0.504
0.0MetTrp: 0.0 ± 0.0
0.549MetTyr: 0.549 ± 0.313
0.0MetXaa: 0.0 ± 0.0
Asn
1.647AsnAla: 1.647 ± 0.94
0.0AsnCys: 0.0 ± 0.0
3.293AsnAsp: 3.293 ± 1.199
0.549AsnGlu: 0.549 ± 0.313
1.647AsnPhe: 1.647 ± 0.91
2.195AsnGly: 2.195 ± 1.253
0.549AsnHis: 0.549 ± 0.313
2.744AsnIle: 2.744 ± 0.504
6.037AsnLys: 6.037 ± 2.654
1.098AsnLeu: 1.098 ± 0.409
0.549AsnMet: 0.549 ± 0.313
1.647AsnAsn: 1.647 ± 0.436
1.647AsnPro: 1.647 ± 0.94
2.744AsnGln: 2.744 ± 0.504
0.549AsnArg: 0.549 ± 0.313
3.293AsnSer: 3.293 ± 1.357
3.293AsnThr: 3.293 ± 1.357
4.94AsnVal: 4.94 ± 1.54
1.098AsnTrp: 1.098 ± 1.187
1.647AsnTyr: 1.647 ± 0.436
0.0AsnXaa: 0.0 ± 0.0
Pro
3.842ProAla: 3.842 ± 1.498
0.0ProCys: 0.0 ± 0.0
5.488ProAsp: 5.488 ± 2.418
2.744ProGlu: 2.744 ± 0.908
0.0ProPhe: 0.0 ± 0.0
1.647ProGly: 1.647 ± 0.94
1.647ProHis: 1.647 ± 0.91
3.293ProIle: 3.293 ± 1.82
1.098ProLys: 1.098 ± 0.409
3.842ProLeu: 3.842 ± 1.049
2.195ProMet: 2.195 ± 1.253
1.098ProAsn: 1.098 ± 0.626
7.684ProPro: 7.684 ± 4.217
2.195ProGln: 2.195 ± 0.64
3.293ProArg: 3.293 ± 0.512
3.842ProSer: 3.842 ± 1.498
4.391ProThr: 4.391 ± 1.28
2.744ProVal: 2.744 ± 0.908
1.647ProTrp: 1.647 ± 0.91
4.391ProTyr: 4.391 ± 1.803
0.0ProXaa: 0.0 ± 0.0
Gln
2.195GlnAla: 2.195 ± 1.253
0.0GlnCys: 0.0 ± 0.0
1.647GlnAsp: 1.647 ± 0.94
2.195GlnGlu: 2.195 ± 0.64
0.549GlnPhe: 0.549 ± 0.583
3.293GlnGly: 3.293 ± 0.585
1.647GlnHis: 1.647 ± 0.94
1.647GlnIle: 1.647 ± 0.957
2.195GlnLys: 2.195 ± 0.666
3.842GlnLeu: 3.842 ± 1.054
0.549GlnMet: 0.549 ± 0.313
0.549GlnAsn: 0.549 ± 0.313
0.549GlnPro: 0.549 ± 0.313
0.549GlnGln: 0.549 ± 0.313
1.647GlnArg: 1.647 ± 0.436
0.549GlnSer: 0.549 ± 0.313
2.744GlnThr: 2.744 ± 0.896
1.098GlnVal: 1.098 ± 0.409
0.549GlnTrp: 0.549 ± 0.313
1.098GlnTyr: 1.098 ± 0.409
0.0GlnXaa: 0.0 ± 0.0
Arg
7.684ArgAla: 7.684 ± 1.831
0.549ArgCys: 0.549 ± 0.583
2.195ArgAsp: 2.195 ± 0.64
4.391ArgGlu: 4.391 ± 0.105
2.195ArgPhe: 2.195 ± 0.666
2.195ArgGly: 2.195 ± 0.64
0.549ArgHis: 0.549 ± 0.313
2.744ArgIle: 2.744 ± 1.566
4.391ArgLys: 4.391 ± 0.93
7.135ArgLeu: 7.135 ± 0.863
2.195ArgMet: 2.195 ± 1.162
2.744ArgAsn: 2.744 ± 0.896
2.744ArgPro: 2.744 ± 0.785
3.293ArgGln: 3.293 ± 1.82
7.135ArgArg: 7.135 ± 2.095
2.744ArgSer: 2.744 ± 0.908
5.488ArgThr: 5.488 ± 1.069
5.488ArgVal: 5.488 ± 1.185
0.0ArgTrp: 0.0 ± 0.0
3.842ArgTyr: 3.842 ± 2.728
0.0ArgXaa: 0.0 ± 0.0
Ser
8.233SerAla: 8.233 ± 3.278
0.0SerCys: 0.0 ± 0.0
4.391SerAsp: 4.391 ± 0.105
2.744SerGlu: 2.744 ± 0.504
2.744SerPhe: 2.744 ± 1.664
3.293SerGly: 3.293 ± 1.199
1.098SerHis: 1.098 ± 0.626
2.744SerIle: 2.744 ± 0.504
2.195SerLys: 2.195 ± 0.64
7.135SerLeu: 7.135 ± 1.164
1.098SerMet: 1.098 ± 0.626
3.842SerAsn: 3.842 ± 1.054
2.744SerPro: 2.744 ± 0.785
1.098SerGln: 1.098 ± 0.409
5.488SerArg: 5.488 ± 1.9
5.488SerSer: 5.488 ± 1.792
4.391SerThr: 4.391 ± 1.759
2.744SerVal: 2.744 ± 1.664
0.549SerTrp: 0.549 ± 0.313
1.098SerTyr: 1.098 ± 0.626
0.0SerXaa: 0.0 ± 0.0
Thr
3.842ThrAla: 3.842 ± 0.28
0.0ThrCys: 0.0 ± 0.0
4.391ThrAsp: 4.391 ± 3.162
2.744ThrGlu: 2.744 ± 1.351
1.098ThrPhe: 1.098 ± 0.626
3.842ThrGly: 3.842 ± 0.28
0.549ThrHis: 0.549 ± 0.313
0.549ThrIle: 0.549 ± 0.313
8.233ThrLys: 8.233 ± 1.513
6.586ThrLeu: 6.586 ± 2.944
2.195ThrMet: 2.195 ± 1.208
2.744ThrAsn: 2.744 ± 0.785
4.94ThrPro: 4.94 ± 1.209
1.647ThrGln: 1.647 ± 1.749
8.782ThrArg: 8.782 ± 2.376
6.037ThrSer: 6.037 ± 0.967
7.135ThrThr: 7.135 ± 1.164
7.684ThrVal: 7.684 ± 0.561
1.098ThrTrp: 1.098 ± 0.626
2.195ThrTyr: 2.195 ± 0.817
0.0ThrXaa: 0.0 ± 0.0
Val
4.94ValAla: 4.94 ± 1.467
0.0ValCys: 0.0 ± 0.0
4.391ValAsp: 4.391 ± 1.759
7.684ValGlu: 7.684 ± 0.815
0.549ValPhe: 0.549 ± 0.313
4.391ValGly: 4.391 ± 1.332
2.195ValHis: 2.195 ± 1.253
3.842ValIle: 3.842 ± 1.498
4.94ValLys: 4.94 ± 1.54
8.233ValLeu: 8.233 ± 2.888
0.549ValMet: 0.549 ± 0.313
2.744ValAsn: 2.744 ± 0.785
6.586ValPro: 6.586 ± 1.305
2.744ValGln: 2.744 ± 0.908
3.293ValArg: 3.293 ± 1.199
3.293ValSer: 3.293 ± 1.226
3.842ValThr: 3.842 ± 1.564
8.782ValVal: 8.782 ± 0.681
0.549ValTrp: 0.549 ± 0.313
2.195ValTyr: 2.195 ± 1.253
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.549TrpAsp: 0.549 ± 0.583
1.098TrpGlu: 1.098 ± 0.626
1.098TrpPhe: 1.098 ± 0.409
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.647TrpLys: 1.647 ± 0.91
1.647TrpLeu: 1.647 ± 0.91
1.647TrpMet: 1.647 ± 0.94
0.549TrpAsn: 0.549 ± 0.313
0.0TrpPro: 0.0 ± 0.0
0.549TrpGln: 0.549 ± 0.313
1.647TrpArg: 1.647 ± 0.91
2.744TrpSer: 2.744 ± 0.504
0.549TrpThr: 0.549 ± 0.313
1.098TrpVal: 1.098 ± 1.187
0.0TrpTrp: 0.0 ± 0.0
1.098TrpTyr: 1.098 ± 1.187
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.098TyrAla: 1.098 ± 0.409
0.549TyrCys: 0.549 ± 0.313
3.293TyrAsp: 3.293 ± 0.512
1.647TyrGlu: 1.647 ± 0.91
0.549TyrPhe: 0.549 ± 0.583
1.098TyrGly: 1.098 ± 0.626
0.549TyrHis: 0.549 ± 0.313
1.098TyrIle: 1.098 ± 0.626
3.842TyrLys: 3.842 ± 0.682
1.647TyrLeu: 1.647 ± 0.94
1.647TyrMet: 1.647 ± 0.763
1.647TyrAsn: 1.647 ± 0.94
2.744TyrPro: 2.744 ± 0.785
0.0TyrGln: 0.0 ± 0.0
2.744TyrArg: 2.744 ± 0.785
4.94TyrSer: 4.94 ± 0.486
2.195TyrThr: 2.195 ± 1.208
2.195TyrVal: 2.195 ± 0.817
0.0TyrTrp: 0.0 ± 0.0
1.647TyrTyr: 1.647 ± 0.436
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.549XaaGln: 0.549 ± 0.583
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1823 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski