Amino acid dipepetide frequency for Eutypa lata (strain UCR-EL1) (Grapevine dieback disease fungus) (Eutypa armeniacae)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.062AlaAla: 11.062 ± 0.076
1.052AlaCys: 1.052 ± 0.013
4.871AlaAsp: 4.871 ± 0.038
5.625AlaGlu: 5.625 ± 0.045
3.335AlaPhe: 3.335 ± 0.026
6.771AlaGly: 6.771 ± 0.052
1.786AlaHis: 1.786 ± 0.02
4.395AlaIle: 4.395 ± 0.034
4.302AlaLys: 4.302 ± 0.035
8.063AlaLeu: 8.063 ± 0.05
2.04AlaMet: 2.04 ± 0.02
3.102AlaAsn: 3.102 ± 0.025
4.605AlaPro: 4.605 ± 0.039
3.308AlaGln: 3.308 ± 0.029
5.154AlaArg: 5.154 ± 0.04
6.795AlaSer: 6.795 ± 0.043
5.774AlaThr: 5.774 ± 0.04
6.089AlaVal: 6.089 ± 0.043
1.305AlaTrp: 1.305 ± 0.018
2.326AlaTyr: 2.326 ± 0.023
0.0AlaXaa: 0.0 ± 0.0
Cys
0.956CysAla: 0.956 ± 0.015
0.202CysCys: 0.202 ± 0.007
0.648CysAsp: 0.648 ± 0.011
0.571CysGlu: 0.571 ± 0.012
0.501CysPhe: 0.501 ± 0.009
0.956CysGly: 0.956 ± 0.015
0.287CysHis: 0.287 ± 0.007
0.64CysIle: 0.64 ± 0.011
0.439CysLys: 0.439 ± 0.009
1.099CysLeu: 1.099 ± 0.017
0.256CysMet: 0.256 ± 0.007
0.393CysAsn: 0.393 ± 0.009
0.586CysPro: 0.586 ± 0.012
0.403CysGln: 0.403 ± 0.009
0.66CysArg: 0.66 ± 0.011
0.774CysSer: 0.774 ± 0.014
0.625CysThr: 0.625 ± 0.013
0.76CysVal: 0.76 ± 0.012
0.196CysTrp: 0.196 ± 0.006
0.344CysTyr: 0.344 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
5.434AspAla: 5.434 ± 0.04
0.616AspCys: 0.616 ± 0.011
5.285AspAsp: 5.285 ± 0.057
4.928AspGlu: 4.928 ± 0.045
2.385AspPhe: 2.385 ± 0.024
4.853AspGly: 4.853 ± 0.037
1.227AspHis: 1.227 ± 0.017
3.157AspIle: 3.157 ± 0.031
2.487AspLys: 2.487 ± 0.025
5.214AspLeu: 5.214 ± 0.039
1.323AspMet: 1.323 ± 0.017
2.047AspAsn: 2.047 ± 0.022
3.53AspPro: 3.53 ± 0.029
1.881AspGln: 1.881 ± 0.019
3.084AspArg: 3.084 ± 0.028
3.901AspSer: 3.901 ± 0.032
3.009AspThr: 3.009 ± 0.025
4.194AspVal: 4.194 ± 0.031
0.996AspTrp: 0.996 ± 0.014
1.723AspTyr: 1.723 ± 0.019
0.0AspXaa: 0.0 ± 0.0
Glu
5.917GluAla: 5.917 ± 0.054
0.613GluCys: 0.613 ± 0.012
4.678GluAsp: 4.678 ± 0.043
5.927GluGlu: 5.927 ± 0.061
2.07GluPhe: 2.07 ± 0.019
4.338GluGly: 4.338 ± 0.028
1.374GluHis: 1.374 ± 0.018
3.062GluIle: 3.062 ± 0.022
3.811GluLys: 3.811 ± 0.033
5.389GluLeu: 5.389 ± 0.038
1.449GluMet: 1.449 ± 0.019
2.324GluAsn: 2.324 ± 0.02
2.697GluPro: 2.697 ± 0.044
2.421GluGln: 2.421 ± 0.028
3.922GluArg: 3.922 ± 0.036
3.98GluSer: 3.98 ± 0.034
3.558GluThr: 3.558 ± 0.031
3.938GluVal: 3.938 ± 0.03
0.941GluTrp: 0.941 ± 0.015
1.769GluTyr: 1.769 ± 0.018
0.0GluXaa: 0.0 ± 0.0
Phe
3.269PheAla: 3.269 ± 0.028
0.532PheCys: 0.532 ± 0.01
2.423PheAsp: 2.423 ± 0.024
2.293PheGlu: 2.293 ± 0.02
1.629PhePhe: 1.629 ± 0.02
3.072PheGly: 3.072 ± 0.03
0.847PheHis: 0.847 ± 0.014
1.753PheIle: 1.753 ± 0.019
1.541PheLys: 1.541 ± 0.02
3.326PheLeu: 3.326 ± 0.03
0.816PheMet: 0.816 ± 0.014
1.448PheAsn: 1.448 ± 0.019
1.87PhePro: 1.87 ± 0.022
1.338PheGln: 1.338 ± 0.017
2.004PheArg: 2.004 ± 0.018
2.714PheSer: 2.714 ± 0.023
2.165PheThr: 2.165 ± 0.023
2.575PheVal: 2.575 ± 0.023
0.682PheTrp: 0.682 ± 0.012
1.164PheTyr: 1.164 ± 0.019
0.0PheXaa: 0.0 ± 0.0
Gly
6.35GlyAla: 6.35 ± 0.044
0.877GlyCys: 0.877 ± 0.013
4.432GlyAsp: 4.432 ± 0.033
4.177GlyGlu: 4.177 ± 0.028
3.023GlyPhe: 3.023 ± 0.032
8.284GlyGly: 8.284 ± 0.081
1.686GlyHis: 1.686 ± 0.021
3.761GlyIle: 3.761 ± 0.031
3.586GlyLys: 3.586 ± 0.035
6.333GlyLeu: 6.333 ± 0.037
1.627GlyMet: 1.627 ± 0.021
2.803GlyAsn: 2.803 ± 0.027
3.381GlyPro: 3.381 ± 0.037
2.488GlyGln: 2.488 ± 0.023
4.343GlyArg: 4.343 ± 0.034
5.968GlySer: 5.968 ± 0.042
4.33GlyThr: 4.33 ± 0.033
5.002GlyVal: 5.002 ± 0.037
1.292GlyTrp: 1.292 ± 0.016
2.254GlyTyr: 2.254 ± 0.025
0.0GlyXaa: 0.0 ± 0.0
His
1.786HisAla: 1.786 ± 0.02
0.284HisCys: 0.284 ± 0.008
1.309HisAsp: 1.309 ± 0.016
1.262HisGlu: 1.262 ± 0.018
0.89HisPhe: 0.89 ± 0.013
1.711HisGly: 1.711 ± 0.021
0.913HisHis: 0.913 ± 0.021
1.122HisIle: 1.122 ± 0.014
0.869HisLys: 0.869 ± 0.014
2.071HisLeu: 2.071 ± 0.023
0.488HisMet: 0.488 ± 0.011
0.811HisAsn: 0.811 ± 0.014
1.506HisPro: 1.506 ± 0.02
0.908HisGln: 0.908 ± 0.014
1.376HisArg: 1.376 ± 0.018
1.486HisSer: 1.486 ± 0.017
1.105HisThr: 1.105 ± 0.015
1.473HisVal: 1.473 ± 0.016
0.347HisTrp: 0.347 ± 0.009
0.71HisTyr: 0.71 ± 0.012
0.0HisXaa: 0.0 ± 0.0
Ile
4.335IleAla: 4.335 ± 0.03
0.659IleCys: 0.659 ± 0.012
3.012IleAsp: 3.012 ± 0.027
2.939IleGlu: 2.939 ± 0.024
1.904IlePhe: 1.904 ± 0.022
3.331IleGly: 3.331 ± 0.027
1.083IleHis: 1.083 ± 0.015
2.458IleIle: 2.458 ± 0.022
2.121IleLys: 2.121 ± 0.023
4.257IleLeu: 4.257 ± 0.033
1.051IleMet: 1.051 ± 0.017
1.761IleAsn: 1.761 ± 0.022
2.899IlePro: 2.899 ± 0.027
1.79IleGln: 1.79 ± 0.022
2.741IleArg: 2.741 ± 0.026
3.466IleSer: 3.466 ± 0.029
2.921IleThr: 2.921 ± 0.026
3.25IleVal: 3.25 ± 0.026
0.72IleTrp: 0.72 ± 0.012
1.364IleTyr: 1.364 ± 0.016
0.0IleXaa: 0.0 ± 0.0
Lys
4.386LysAla: 4.386 ± 0.035
0.415LysCys: 0.415 ± 0.011
2.84LysAsp: 2.84 ± 0.03
3.396LysGlu: 3.396 ± 0.031
1.485LysPhe: 1.485 ± 0.018
3.146LysGly: 3.146 ± 0.034
1.068LysHis: 1.068 ± 0.016
2.207LysIle: 2.207 ± 0.023
3.459LysLys: 3.459 ± 0.048
4.024LysLeu: 4.024 ± 0.032
1.02LysMet: 1.02 ± 0.014
1.703LysAsn: 1.703 ± 0.021
2.6LysPro: 2.6 ± 0.027
1.816LysGln: 1.816 ± 0.02
3.104LysArg: 3.104 ± 0.028
3.184LysSer: 3.184 ± 0.028
2.865LysThr: 2.865 ± 0.028
2.965LysVal: 2.965 ± 0.027
0.677LysTrp: 0.677 ± 0.013
1.389LysTyr: 1.389 ± 0.019
0.0LysXaa: 0.0 ± 0.0
Leu
8.118LeuAla: 8.118 ± 0.04
1.101LeuCys: 1.101 ± 0.014
5.329LeuAsp: 5.329 ± 0.036
5.625LeuGlu: 5.625 ± 0.043
3.262LeuPhe: 3.262 ± 0.029
6.245LeuGly: 6.245 ± 0.038
2.029LeuHis: 2.029 ± 0.02
3.701LeuIle: 3.701 ± 0.035
4.093LeuLys: 4.093 ± 0.031
8.127LeuLeu: 8.127 ± 0.059
1.793LeuMet: 1.793 ± 0.02
3.035LeuAsn: 3.035 ± 0.025
5.051LeuPro: 5.051 ± 0.035
3.514LeuGln: 3.514 ± 0.029
5.62LeuArg: 5.62 ± 0.038
6.486LeuSer: 6.486 ± 0.041
4.701LeuThr: 4.701 ± 0.036
5.687LeuVal: 5.687 ± 0.04
1.247LeuTrp: 1.247 ± 0.018
2.318LeuTyr: 2.318 ± 0.028
0.0LeuXaa: 0.0 ± 0.0
Met
2.3MetAla: 2.3 ± 0.021
0.245MetCys: 0.245 ± 0.007
1.255MetAsp: 1.255 ± 0.017
1.266MetGlu: 1.266 ± 0.015
0.764MetPhe: 0.764 ± 0.013
1.518MetGly: 1.518 ± 0.017
0.456MetHis: 0.456 ± 0.01
0.961MetIle: 0.961 ± 0.016
1.006MetLys: 1.006 ± 0.015
1.812MetLeu: 1.812 ± 0.019
0.616MetMet: 0.616 ± 0.012
0.774MetAsn: 0.774 ± 0.013
1.203MetPro: 1.203 ± 0.016
0.821MetGln: 0.821 ± 0.013
1.291MetArg: 1.291 ± 0.015
1.692MetSer: 1.692 ± 0.021
1.326MetThr: 1.326 ± 0.016
1.38MetVal: 1.38 ± 0.019
0.295MetTrp: 0.295 ± 0.008
0.538MetTyr: 0.538 ± 0.012
0.0MetXaa: 0.0 ± 0.0
Asn
3.223AsnAla: 3.223 ± 0.028
0.413AsnCys: 0.413 ± 0.01
2.068AsnAsp: 2.068 ± 0.02
2.051AsnGlu: 2.051 ± 0.022
1.4AsnPhe: 1.4 ± 0.016
3.199AsnGly: 3.199 ± 0.031
0.802AsnHis: 0.802 ± 0.013
1.979AsnIle: 1.979 ± 0.022
1.557AsnLys: 1.557 ± 0.017
3.159AsnLeu: 3.159 ± 0.028
0.798AsnMet: 0.798 ± 0.014
1.882AsnAsn: 1.882 ± 0.025
2.323AsnPro: 2.323 ± 0.022
1.252AsnGln: 1.252 ± 0.02
1.838AsnArg: 1.838 ± 0.022
2.567AsnSer: 2.567 ± 0.025
2.146AsnThr: 2.146 ± 0.023
2.363AsnVal: 2.363 ± 0.021
0.589AsnTrp: 0.589 ± 0.01
1.079AsnTyr: 1.079 ± 0.015
0.0AsnXaa: 0.0 ± 0.0
Pro
4.899ProAla: 4.899 ± 0.044
0.439ProCys: 0.439 ± 0.009
3.344ProAsp: 3.344 ± 0.026
3.925ProGlu: 3.925 ± 0.043
1.969ProPhe: 1.969 ± 0.022
4.043ProGly: 4.043 ± 0.048
1.169ProHis: 1.169 ± 0.014
2.391ProIle: 2.391 ± 0.023
2.462ProLys: 2.462 ± 0.023
4.398ProLeu: 4.398 ± 0.034
0.984ProMet: 0.984 ± 0.016
2.046ProAsn: 2.046 ± 0.022
4.432ProPro: 4.432 ± 0.052
2.15ProGln: 2.15 ± 0.023
2.916ProArg: 2.916 ± 0.022
4.874ProSer: 4.874 ± 0.042
3.734ProThr: 3.734 ± 0.036
3.388ProVal: 3.388 ± 0.03
0.772ProTrp: 0.772 ± 0.014
1.446ProTyr: 1.446 ± 0.018
0.0ProXaa: 0.0 ± 0.0
Gln
3.315GlnAla: 3.315 ± 0.029
0.401GlnCys: 0.401 ± 0.01
2.053GlnAsp: 2.053 ± 0.024
2.352GlnGlu: 2.352 ± 0.027
1.277GlnPhe: 1.277 ± 0.018
2.371GlnGly: 2.371 ± 0.022
0.999GlnHis: 0.999 ± 0.018
1.758GlnIle: 1.758 ± 0.021
1.909GlnLys: 1.909 ± 0.022
3.308GlnLeu: 3.308 ± 0.033
0.836GlnMet: 0.836 ± 0.015
1.386GlnAsn: 1.386 ± 0.018
2.199GlnPro: 2.199 ± 0.025
2.816GlnGln: 2.816 ± 0.055
2.423GlnArg: 2.423 ± 0.025
2.564GlnSer: 2.564 ± 0.029
2.076GlnThr: 2.076 ± 0.021
2.203GlnVal: 2.203 ± 0.021
0.603GlnTrp: 0.603 ± 0.012
1.104GlnTyr: 1.104 ± 0.017
0.0GlnXaa: 0.0 ± 0.0
Arg
4.879ArgAla: 4.879 ± 0.034
0.635ArgCys: 0.635 ± 0.013
3.622ArgAsp: 3.622 ± 0.034
3.869ArgGlu: 3.869 ± 0.035
2.18ArgPhe: 2.18 ± 0.023
3.983ArgGly: 3.983 ± 0.036
1.429ArgHis: 1.429 ± 0.018
2.799ArgIle: 2.799 ± 0.025
3.126ArgLys: 3.126 ± 0.026
5.237ArgLeu: 5.237 ± 0.04
1.285ArgMet: 1.285 ± 0.016
2.149ArgAsn: 2.149 ± 0.023
2.969ArgPro: 2.969 ± 0.024
2.432ArgGln: 2.432 ± 0.028
4.738ArgArg: 4.738 ± 0.045
3.996ArgSer: 3.996 ± 0.034
3.01ArgThr: 3.01 ± 0.024
3.498ArgVal: 3.498 ± 0.026
0.981ArgTrp: 0.981 ± 0.015
1.656ArgTyr: 1.656 ± 0.018
0.0ArgXaa: 0.0 ± 0.0
Ser
6.294SerAla: 6.294 ± 0.042
0.74SerCys: 0.74 ± 0.014
4.088SerAsp: 4.088 ± 0.029
3.993SerGlu: 3.993 ± 0.032
2.786SerPhe: 2.786 ± 0.026
5.815SerGly: 5.815 ± 0.042
1.64SerHis: 1.64 ± 0.018
3.596SerIle: 3.596 ± 0.024
3.441SerLys: 3.441 ± 0.031
6.347SerLeu: 6.347 ± 0.04
1.55SerMet: 1.55 ± 0.019
2.817SerAsn: 2.817 ± 0.027
4.344SerPro: 4.344 ± 0.039
2.742SerGln: 2.742 ± 0.03
4.159SerArg: 4.159 ± 0.033
7.988SerSer: 7.988 ± 0.073
4.876SerThr: 4.876 ± 0.041
4.311SerVal: 4.311 ± 0.033
1.082SerTrp: 1.082 ± 0.017
1.99SerTyr: 1.99 ± 0.023
0.0SerXaa: 0.0 ± 0.0
Thr
5.601ThrAla: 5.601 ± 0.042
0.7ThrCys: 0.7 ± 0.013
2.973ThrAsp: 2.973 ± 0.024
3.173ThrGlu: 3.173 ± 0.028
2.226ThrPhe: 2.226 ± 0.021
4.453ThrGly: 4.453 ± 0.04
1.202ThrHis: 1.202 ± 0.016
3.142ThrIle: 3.142 ± 0.029
2.627ThrLys: 2.627 ± 0.026
5.021ThrLeu: 5.021 ± 0.033
1.193ThrMet: 1.193 ± 0.015
2.171ThrAsn: 2.171 ± 0.024
3.894ThrPro: 3.894 ± 0.03
1.953ThrGln: 1.953 ± 0.022
2.931ThrArg: 2.931 ± 0.025
4.845ThrSer: 4.845 ± 0.04
4.933ThrThr: 4.933 ± 0.047
3.852ThrVal: 3.852 ± 0.033
0.904ThrTrp: 0.904 ± 0.014
1.66ThrTyr: 1.66 ± 0.022
0.0ThrXaa: 0.0 ± 0.0
Val
6.012ValAla: 6.012 ± 0.037
0.786ValCys: 0.786 ± 0.014
4.174ValAsp: 4.174 ± 0.029
4.241ValGlu: 4.241 ± 0.035
2.554ValPhe: 2.554 ± 0.026
4.589ValGly: 4.589 ± 0.035
1.361ValHis: 1.361 ± 0.019
3.057ValIle: 3.057 ± 0.027
2.962ValLys: 2.962 ± 0.027
5.867ValLeu: 5.867 ± 0.043
1.369ValMet: 1.369 ± 0.017
2.294ValAsn: 2.294 ± 0.022
3.604ValPro: 3.604 ± 0.027
2.318ValGln: 2.318 ± 0.021
3.567ValArg: 3.567 ± 0.028
4.422ValSer: 4.422 ± 0.029
3.73ValThr: 3.73 ± 0.029
5.004ValVal: 5.004 ± 0.04
0.974ValTrp: 0.974 ± 0.017
1.837ValTyr: 1.837 ± 0.018
0.0ValXaa: 0.0 ± 0.0
Trp
1.277TrpAla: 1.277 ± 0.02
0.192TrpCys: 0.192 ± 0.006
1.056TrpAsp: 1.056 ± 0.016
0.93TrpGlu: 0.93 ± 0.013
0.588TrpPhe: 0.588 ± 0.012
1.076TrpGly: 1.076 ± 0.018
0.358TrpHis: 0.358 ± 0.009
0.776TrpIle: 0.776 ± 0.012
0.819TrpLys: 0.819 ± 0.015
1.383TrpLeu: 1.383 ± 0.019
0.384TrpMet: 0.384 ± 0.009
0.637TrpAsn: 0.637 ± 0.011
0.624TrpPro: 0.624 ± 0.012
0.558TrpGln: 0.558 ± 0.01
0.995TrpArg: 0.995 ± 0.015
1.023TrpSer: 1.023 ± 0.014
0.957TrpThr: 0.957 ± 0.016
0.976TrpVal: 0.976 ± 0.014
0.29TrpTrp: 0.29 ± 0.008
0.482TrpTyr: 0.482 ± 0.011
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.346TyrAla: 2.346 ± 0.023
0.394TyrCys: 0.394 ± 0.009
1.814TyrAsp: 1.814 ± 0.02
1.636TyrGlu: 1.636 ± 0.018
1.232TyrPhe: 1.232 ± 0.018
2.243TyrGly: 2.243 ± 0.025
0.708TyrHis: 0.708 ± 0.014
1.348TyrIle: 1.348 ± 0.016
1.13TyrLys: 1.13 ± 0.015
2.646TyrLeu: 2.646 ± 0.028
0.637TyrMet: 0.637 ± 0.012
1.106TyrAsn: 1.106 ± 0.016
1.465TyrPro: 1.465 ± 0.017
1.043TyrGln: 1.043 ± 0.015
1.607TyrArg: 1.607 ± 0.017
1.876TyrSer: 1.876 ± 0.02
1.615TyrThr: 1.615 ± 0.019
1.814TyrVal: 1.814 ± 0.021
0.49TyrTrp: 0.49 ± 0.01
0.991TyrTyr: 0.991 ± 0.016
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 11684 proteins (5038052 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski