Amino acid dipepetide frequency for Flavisolibacter tropicus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.704AlaAla: 6.704 ± 0.117	0.738AlaCys: 0.738 ± 0.049	3.922AlaAsp: 3.922 ± 0.055	4.016AlaGlu: 4.016 ± 0.059	3.809AlaPhe: 3.809 ± 0.052	5.48AlaGly: 5.48 ± 0.084	1.357AlaHis: 1.357 ± 0.041	5.547AlaIle: 5.547 ± 0.071	4.465AlaLys: 4.465 ± 0.067	7.141AlaLeu: 7.141 ± 0.079	1.695AlaMet: 1.695 ± 0.035	3.84AlaAsn: 3.84 ± 0.048	2.609AlaPro: 2.609 ± 0.065	3.166AlaGln: 3.166 ± 0.054	2.551AlaArg: 2.551 ± 0.048	4.837AlaSer: 4.837 ± 0.079	4.847AlaThr: 4.847 ± 0.089	4.981AlaVal: 4.981 ± 0.061	0.869AlaTrp: 0.869 ± 0.029	2.873AlaTyr: 2.873 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	0.517CysAla: 0.517 ± 0.022	0.132CysCys: 0.132 ± 0.009	0.444CysAsp: 0.444 ± 0.031	0.414CysGlu: 0.414 ± 0.017	0.467CysPhe: 0.467 ± 0.019	0.666CysGly: 0.666 ± 0.026	0.207CysHis: 0.207 ± 0.014	0.682CysIle: 0.682 ± 0.022	0.471CysLys: 0.471 ± 0.02	0.803CysLeu: 0.803 ± 0.024	0.2CysMet: 0.2 ± 0.011	0.453CysAsn: 0.453 ± 0.023	0.348CysPro: 0.348 ± 0.018	0.35CysGln: 0.35 ± 0.029	0.302CysArg: 0.302 ± 0.017	0.624CysSer: 0.624 ± 0.028	0.513CysThr: 0.513 ± 0.021	0.449CysVal: 0.449 ± 0.018	0.101CysTrp: 0.101 ± 0.008	0.324CysTyr: 0.324 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	4.036AspAla: 4.036 ± 0.059	0.366AspCys: 0.366 ± 0.016	2.308AspAsp: 2.308 ± 0.043	3.018AspGlu: 3.018 ± 0.048	2.561AspPhe: 2.561 ± 0.046	3.562AspGly: 3.562 ± 0.06	0.914AspHis: 0.914 ± 0.02	3.541AspIle: 3.541 ± 0.049	3.434AspLys: 3.434 ± 0.055	4.594AspLeu: 4.594 ± 0.055	1.117AspMet: 1.117 ± 0.026	2.544AspAsn: 2.544 ± 0.041	2.096AspPro: 2.096 ± 0.04	1.728AspGln: 1.728 ± 0.04	2.063AspArg: 2.063 ± 0.045	3.018AspSer: 3.018 ± 0.054	2.689AspThr: 2.689 ± 0.049	3.539AspVal: 3.539 ± 0.055	0.776AspTrp: 0.776 ± 0.023	2.386AspTyr: 2.386 ± 0.036	0.0AspXaa: 0.0 ± 0.0
Glu	4.573GluAla: 4.573 ± 0.061	0.356GluCys: 0.356 ± 0.016	2.658GluAsp: 2.658 ± 0.048	4.199GluGlu: 4.199 ± 0.071	2.16GluPhe: 2.16 ± 0.037	3.674GluGly: 3.674 ± 0.054	1.13GluHis: 1.13 ± 0.028	3.656GluIle: 3.656 ± 0.062	4.717GluLys: 4.717 ± 0.08	5.636GluLeu: 5.636 ± 0.082	1.481GluMet: 1.481 ± 0.033	3.009GluAsn: 3.009 ± 0.045	1.685GluPro: 1.685 ± 0.037	2.719GluGln: 2.719 ± 0.048	2.731GluArg: 2.731 ± 0.047	2.799GluSer: 2.799 ± 0.048	2.971GluThr: 2.971 ± 0.049	3.913GluVal: 3.913 ± 0.06	0.779GluTrp: 0.779 ± 0.024	2.021GluTyr: 2.021 ± 0.04	0.0GluXaa: 0.0 ± 0.0
Phe	3.269PheAla: 3.269 ± 0.049	0.463PheCys: 0.463 ± 0.018	2.692PheAsp: 2.692 ± 0.045	2.571PheGlu: 2.571 ± 0.039	2.537PhePhe: 2.537 ± 0.059	3.249PheGly: 3.249 ± 0.052	0.921PheHis: 0.921 ± 0.024	3.528PheIle: 3.528 ± 0.062	2.911PheLys: 2.911 ± 0.047	4.517PheLeu: 4.517 ± 0.076	1.013PheMet: 1.013 ± 0.027	2.721PheAsn: 2.721 ± 0.049	1.778PhePro: 1.778 ± 0.038	1.776PheGln: 1.776 ± 0.037	1.844PheArg: 1.844 ± 0.036	3.608PheSer: 3.608 ± 0.052	3.225PheThr: 3.225 ± 0.05	2.911PheVal: 2.911 ± 0.048	0.634PheTrp: 0.634 ± 0.022	2.141PheTyr: 2.141 ± 0.04	0.0PheXaa: 0.0 ± 0.0
Gly	4.775GlyAla: 4.775 ± 0.081	0.787GlyCys: 0.787 ± 0.042	3.155GlyAsp: 3.155 ± 0.047	3.414GlyGlu: 3.414 ± 0.052	3.625GlyPhe: 3.625 ± 0.054	5.035GlyGly: 5.035 ± 0.097	1.253GlyHis: 1.253 ± 0.033	4.953GlyIle: 4.953 ± 0.059	5.015GlyLys: 5.015 ± 0.065	6.116GlyLeu: 6.116 ± 0.073	1.658GlyMet: 1.658 ± 0.036	3.713GlyAsn: 3.713 ± 0.062	1.654GlyPro: 1.654 ± 0.038	2.617GlyGln: 2.617 ± 0.067	2.717GlyArg: 2.717 ± 0.05	4.333GlySer: 4.333 ± 0.074	4.327GlyThr: 4.327 ± 0.09	4.586GlyVal: 4.586 ± 0.064	1.026GlyTrp: 1.026 ± 0.029	3.054GlyTyr: 3.054 ± 0.047	0.0GlyXaa: 0.0 ± 0.0
His	1.229HisAla: 1.229 ± 0.025	0.215HisCys: 0.215 ± 0.013	0.843HisAsp: 0.843 ± 0.023	0.96HisGlu: 0.96 ± 0.024	1.217HisPhe: 1.217 ± 0.029	1.135HisGly: 1.135 ± 0.028	0.562HisHis: 0.562 ± 0.024	1.33HisIle: 1.33 ± 0.033	1.119HisLys: 1.119 ± 0.03	2.003HisLeu: 2.003 ± 0.043	0.405HisMet: 0.405 ± 0.016	0.92HisAsn: 0.92 ± 0.022	1.09HisPro: 1.09 ± 0.028	0.886HisGln: 0.886 ± 0.026	0.795HisArg: 0.795 ± 0.022	1.177HisSer: 1.177 ± 0.03	1.2HisThr: 1.2 ± 0.037	1.053HisVal: 1.053 ± 0.026	0.283HisTrp: 0.283 ± 0.013	0.931HisTyr: 0.931 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	5.456IleAla: 5.456 ± 0.072	0.674IleCys: 0.674 ± 0.033	3.929IleAsp: 3.929 ± 0.052	4.104IleGlu: 4.104 ± 0.06	2.516IlePhe: 2.516 ± 0.05	4.745IleGly: 4.745 ± 0.068	1.421IleHis: 1.421 ± 0.033	4.599IleIle: 4.599 ± 0.07	4.553IleLys: 4.553 ± 0.058	5.79IleLeu: 5.79 ± 0.079	1.238IleMet: 1.238 ± 0.032	3.985IleAsn: 3.985 ± 0.055	2.959IlePro: 2.959 ± 0.046	2.615IleGln: 2.615 ± 0.04	2.826IleArg: 2.826 ± 0.05	4.533IleSer: 4.533 ± 0.058	4.53IleThr: 4.53 ± 0.066	4.34IleVal: 4.34 ± 0.059	0.711IleTrp: 0.711 ± 0.023	2.493IleTyr: 2.493 ± 0.042	0.0IleXaa: 0.0 ± 0.0
Lys	5.262LysAla: 5.262 ± 0.072	0.341LysCys: 0.341 ± 0.019	3.958LysAsp: 3.958 ± 0.053	5.403LysGlu: 5.403 ± 0.077	2.069LysPhe: 2.069 ± 0.038	4.878LysGly: 4.878 ± 0.064	1.266LysHis: 1.266 ± 0.036	3.891LysIle: 3.891 ± 0.057	5.123LysLys: 5.123 ± 0.07	5.643LysLeu: 5.643 ± 0.063	1.724LysMet: 1.724 ± 0.039	3.526LysAsn: 3.526 ± 0.048	2.712LysPro: 2.712 ± 0.048	3.128LysGln: 3.128 ± 0.045	3.082LysArg: 3.082 ± 0.05	3.543LysSer: 3.543 ± 0.052	3.889LysThr: 3.889 ± 0.052	4.45LysVal: 4.45 ± 0.062	0.899LysTrp: 0.899 ± 0.026	2.44LysTyr: 2.44 ± 0.043	0.0LysXaa: 0.0 ± 0.0
Leu	6.677LeuAla: 6.677 ± 0.068	0.848LeuCys: 0.848 ± 0.025	4.378LeuAsp: 4.378 ± 0.057	4.994LeuGlu: 4.994 ± 0.072	5.094LeuPhe: 5.094 ± 0.089	5.747LeuGly: 5.747 ± 0.073	1.932LeuHis: 1.932 ± 0.045	6.016LeuIle: 6.016 ± 0.085	6.479LeuLys: 6.479 ± 0.069	10.213LeuLeu: 10.213 ± 0.145	2.112LeuMet: 2.112 ± 0.04	5.096LeuAsn: 5.096 ± 0.058	4.288LeuPro: 4.288 ± 0.06	4.564LeuGln: 4.564 ± 0.064	3.929LeuArg: 3.929 ± 0.05	6.664LeuSer: 6.664 ± 0.069	5.693LeuThr: 5.693 ± 0.082	5.931LeuVal: 5.931 ± 0.076	1.055LeuTrp: 1.055 ± 0.033	3.461LeuTyr: 3.461 ± 0.055	0.0LeuXaa: 0.0 ± 0.0
Met	1.887MetAla: 1.887 ± 0.038	0.124MetCys: 0.124 ± 0.009	1.169MetAsp: 1.169 ± 0.028	1.355MetGlu: 1.355 ± 0.033	0.759MetPhe: 0.759 ± 0.023	1.477MetGly: 1.477 ± 0.031	0.471MetHis: 0.471 ± 0.018	1.36MetIle: 1.36 ± 0.033	1.873MetLys: 1.873 ± 0.038	2.048MetLeu: 2.048 ± 0.042	0.587MetMet: 0.587 ± 0.02	1.221MetAsn: 1.221 ± 0.03	1.061MetPro: 1.061 ± 0.031	1.149MetGln: 1.149 ± 0.029	1.101MetArg: 1.101 ± 0.027	1.25MetSer: 1.25 ± 0.032	1.134MetThr: 1.134 ± 0.029	1.453MetVal: 1.453 ± 0.03	0.22MetTrp: 0.22 ± 0.011	0.724MetTyr: 0.724 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	4.102AsnAla: 4.102 ± 0.071	0.448AsnCys: 0.448 ± 0.02	2.743AsnAsp: 2.743 ± 0.045	3.05AsnGlu: 3.05 ± 0.045	2.308AsnPhe: 2.308 ± 0.049	4.211AsnGly: 4.211 ± 0.08	0.946AsnHis: 0.946 ± 0.026	3.594AsnIle: 3.594 ± 0.048	3.639AsnLys: 3.639 ± 0.052	4.476AsnLeu: 4.476 ± 0.065	1.121AsnMet: 1.121 ± 0.025	3.371AsnAsn: 3.371 ± 0.066	2.548AsnPro: 2.548 ± 0.051	2.14AsnGln: 2.14 ± 0.044	2.479AsnArg: 2.479 ± 0.049	3.178AsnSer: 3.178 ± 0.059	3.435AsnThr: 3.435 ± 0.067	3.282AsnVal: 3.282 ± 0.058	0.776AsnTrp: 0.776 ± 0.023	2.52AsnTyr: 2.52 ± 0.047	0.0AsnXaa: 0.0 ± 0.0
Pro	3.328ProAla: 3.328 ± 0.078	0.247ProCys: 0.247 ± 0.014	2.254ProAsp: 2.254 ± 0.043	2.435ProGlu: 2.435 ± 0.052	2.086ProPhe: 2.086 ± 0.042	2.543ProGly: 2.543 ± 0.047	0.753ProHis: 0.753 ± 0.024	2.534ProIle: 2.534 ± 0.041	2.183ProLys: 2.183 ± 0.043	3.478ProLeu: 3.478 ± 0.043	0.783ProMet: 0.783 ± 0.025	2.094ProAsn: 2.094 ± 0.046	1.121ProPro: 1.121 ± 0.034	1.536ProGln: 1.536 ± 0.034	1.164ProArg: 1.164 ± 0.031	2.517ProSer: 2.517 ± 0.043	2.419ProThr: 2.419 ± 0.048	3.153ProVal: 3.153 ± 0.053	0.442ProTrp: 0.442 ± 0.019	1.731ProTyr: 1.731 ± 0.048	0.0ProXaa: 0.0 ± 0.0
Gln	3.103GlnAla: 3.103 ± 0.068	0.26GlnCys: 0.26 ± 0.016	1.707GlnAsp: 1.707 ± 0.033	2.461GlnGlu: 2.461 ± 0.043	1.976GlnPhe: 1.976 ± 0.036	2.291GlnGly: 2.291 ± 0.046	0.942GlnHis: 0.942 ± 0.025	2.323GlnIle: 2.323 ± 0.037	2.912GlnLys: 2.912 ± 0.043	4.834GlnLeu: 4.834 ± 0.069	1.019GlnMet: 1.019 ± 0.028	2.022GlnAsn: 2.022 ± 0.038	1.811GlnPro: 1.811 ± 0.036	2.641GlnGln: 2.641 ± 0.054	1.909GlnArg: 1.909 ± 0.039	2.432GlnSer: 2.432 ± 0.048	2.451GlnThr: 2.451 ± 0.05	2.753GlnVal: 2.753 ± 0.038	0.673GlnTrp: 0.673 ± 0.024	1.781GlnTyr: 1.781 ± 0.036	0.0GlnXaa: 0.0 ± 0.0
Arg	2.331ArgAla: 2.331 ± 0.049	0.287ArgCys: 0.287 ± 0.014	1.865ArgAsp: 1.865 ± 0.038	2.204ArgGlu: 2.204 ± 0.044	2.374ArgPhe: 2.374 ± 0.038	2.181ArgGly: 2.181 ± 0.043	0.78ArgHis: 0.78 ± 0.021	3.175ArgIle: 3.175 ± 0.047	3.043ArgLys: 3.043 ± 0.049	4.211ArgLeu: 4.211 ± 0.065	1.139ArgMet: 1.139 ± 0.029	2.346ArgAsn: 2.346 ± 0.043	1.458ArgPro: 1.458 ± 0.036	1.834ArgGln: 1.834 ± 0.039	1.851ArgArg: 1.851 ± 0.039	2.479ArgSer: 2.479 ± 0.044	2.275ArgThr: 2.275 ± 0.04	2.488ArgVal: 2.488 ± 0.038	0.608ArgTrp: 0.608 ± 0.019	1.906ArgTyr: 1.906 ± 0.034	0.0ArgXaa: 0.0 ± 0.0
Ser	4.508SerAla: 4.508 ± 0.067	0.6SerCys: 0.6 ± 0.018	2.915SerAsp: 2.915 ± 0.043	3.016SerGlu: 3.016 ± 0.056	3.8SerPhe: 3.8 ± 0.064	4.716SerGly: 4.716 ± 0.084	1.143SerHis: 1.143 ± 0.028	4.768SerIle: 4.768 ± 0.059	3.807SerLys: 3.807 ± 0.05	6.463SerLeu: 6.463 ± 0.081	1.386SerMet: 1.386 ± 0.029	3.437SerAsn: 3.437 ± 0.059	2.251SerPro: 2.251 ± 0.045	2.219SerGln: 2.219 ± 0.039	2.397SerArg: 2.397 ± 0.047	4.425SerSer: 4.425 ± 0.074	3.843SerThr: 3.843 ± 0.071	4.115SerVal: 4.115 ± 0.081	0.824SerTrp: 0.824 ± 0.021	2.81SerTyr: 2.81 ± 0.041	0.0SerXaa: 0.0 ± 0.0
Thr	5.051ThrAla: 5.051 ± 0.081	0.446ThrCys: 0.446 ± 0.017	3.173ThrAsp: 3.173 ± 0.053	3.01ThrGlu: 3.01 ± 0.043	2.843ThrPhe: 2.843 ± 0.05	4.593ThrGly: 4.593 ± 0.068	1.058ThrHis: 1.058 ± 0.027	4.74ThrIle: 4.74 ± 0.083	3.363ThrLys: 3.363 ± 0.053	5.718ThrLeu: 5.718 ± 0.096	1.027ThrMet: 1.027 ± 0.03	3.181ThrAsn: 3.181 ± 0.064	2.87ThrPro: 2.87 ± 0.049	2.204ThrGln: 2.204 ± 0.069	1.984ThrArg: 1.984 ± 0.034	4.058ThrSer: 4.058 ± 0.071	4.281ThrThr: 4.281 ± 0.098	4.342ThrVal: 4.342 ± 0.076	0.776ThrTrp: 0.776 ± 0.037	2.551ThrTyr: 2.551 ± 0.063	0.0ThrXaa: 0.0 ± 0.0
Val	5.011ValAla: 5.011 ± 0.059	0.634ValCys: 0.634 ± 0.019	3.397ValAsp: 3.397 ± 0.049	3.532ValGlu: 3.532 ± 0.059	3.147ValPhe: 3.147 ± 0.051	4.047ValGly: 4.047 ± 0.054	1.196ValHis: 1.196 ± 0.032	4.49ValIle: 4.49 ± 0.054	4.404ValLys: 4.404 ± 0.058	6.297ValLeu: 6.297 ± 0.077	1.516ValMet: 1.516 ± 0.032	3.615ValAsn: 3.615 ± 0.07	2.546ValPro: 2.546 ± 0.043	2.516ValGln: 2.516 ± 0.043	2.531ValArg: 2.531 ± 0.046	4.409ValSer: 4.409 ± 0.061	4.158ValThr: 4.158 ± 0.085	4.7ValVal: 4.7 ± 0.081	0.771ValTrp: 0.771 ± 0.024	2.518ValTyr: 2.518 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	0.85TrpAla: 0.85 ± 0.028	0.115TrpCys: 0.115 ± 0.009	0.652TrpAsp: 0.652 ± 0.024	0.658TrpGlu: 0.658 ± 0.019	0.609TrpPhe: 0.609 ± 0.022	0.842TrpGly: 0.842 ± 0.024	0.283TrpHis: 0.283 ± 0.018	0.806TrpIle: 0.806 ± 0.025	0.97TrpLys: 0.97 ± 0.027	1.359TrpLeu: 1.359 ± 0.038	0.409TrpMet: 0.409 ± 0.018	0.793TrpAsn: 0.793 ± 0.037	0.349TrpPro: 0.349 ± 0.015	0.678TrpGln: 0.678 ± 0.024	0.598TrpArg: 0.598 ± 0.02	0.796TrpSer: 0.796 ± 0.025	0.681TrpThr: 0.681 ± 0.026	0.806TrpVal: 0.806 ± 0.025	0.225TrpTrp: 0.225 ± 0.013	0.521TrpTyr: 0.521 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.78TyrAla: 2.78 ± 0.05	0.388TyrCys: 0.388 ± 0.016	2.128TyrAsp: 2.128 ± 0.038	2.052TyrGlu: 2.052 ± 0.043	2.353TyrPhe: 2.353 ± 0.045	2.74TyrGly: 2.74 ± 0.047	0.819TyrHis: 0.819 ± 0.023	2.488TyrIle: 2.488 ± 0.041	2.746TyrLys: 2.746 ± 0.044	3.829TyrLeu: 3.829 ± 0.053	0.791TyrMet: 0.791 ± 0.024	2.48TyrAsn: 2.48 ± 0.047	1.567TyrPro: 1.567 ± 0.033	1.836TyrGln: 1.836 ± 0.041	1.982TyrArg: 1.982 ± 0.034	2.761TyrSer: 2.761 ± 0.043	2.707TyrThr: 2.707 ± 0.061	2.188TyrVal: 2.188 ± 0.038	0.551TyrTrp: 0.551 ± 0.018	1.982TyrTyr: 1.982 ± 0.043	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4588 proteins (1527984 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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