Amino acid dipepetide frequency for Tortoise microvirus 77

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.747AlaAla: 10.747 ± 4.712
0.0AlaCys: 0.0 ± 0.0
5.09AlaAsp: 5.09 ± 1.782
6.787AlaGlu: 6.787 ± 2.469
3.959AlaPhe: 3.959 ± 1.013
7.353AlaGly: 7.353 ± 1.69
3.394AlaHis: 3.394 ± 1.898
5.656AlaIle: 5.656 ± 1.858
7.353AlaLys: 7.353 ± 3.176
6.222AlaLeu: 6.222 ± 1.83
3.394AlaMet: 3.394 ± 0.872
1.697AlaAsn: 1.697 ± 0.841
13.009AlaPro: 13.009 ± 3.402
3.394AlaGln: 3.394 ± 2.046
9.05AlaArg: 9.05 ± 4.362
2.828AlaSer: 2.828 ± 1.174
6.222AlaThr: 6.222 ± 1.418
7.919AlaVal: 7.919 ± 2.994
1.697AlaTrp: 1.697 ± 0.827
3.394AlaTyr: 3.394 ± 0.883
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.566CysLys: 0.566 ± 0.578
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.131CysSer: 1.131 ± 0.831
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.656AspAla: 5.656 ± 1.926
0.0AspCys: 0.0 ± 0.0
4.525AspAsp: 4.525 ± 1.305
1.131AspGlu: 1.131 ± 0.831
1.697AspPhe: 1.697 ± 1.023
4.525AspGly: 4.525 ± 1.054
0.566AspHis: 0.566 ± 0.558
2.262AspIle: 2.262 ± 0.922
1.697AspLys: 1.697 ± 0.909
5.656AspLeu: 5.656 ± 2.14
0.566AspMet: 0.566 ± 0.416
0.0AspAsn: 0.0 ± 0.0
7.353AspPro: 7.353 ± 1.302
2.828AspGln: 2.828 ± 1.565
3.959AspArg: 3.959 ± 1.841
3.959AspSer: 3.959 ± 1.068
3.394AspThr: 3.394 ± 1.589
2.828AspVal: 2.828 ± 0.642
1.697AspTrp: 1.697 ± 1.229
1.697AspTyr: 1.697 ± 0.673
0.0AspXaa: 0.0 ± 0.0
Glu
6.222GluAla: 6.222 ± 1.952
0.0GluCys: 0.0 ± 0.0
2.262GluAsp: 2.262 ± 0.749
1.697GluGlu: 1.697 ± 0.825
1.131GluPhe: 1.131 ± 0.937
3.959GluGly: 3.959 ± 1.287
1.131GluHis: 1.131 ± 0.615
0.566GluIle: 0.566 ± 0.598
2.262GluLys: 2.262 ± 0.749
7.919GluLeu: 7.919 ± 2.615
1.697GluMet: 1.697 ± 1.114
1.131GluAsn: 1.131 ± 0.615
3.394GluPro: 3.394 ± 1.615
3.394GluGln: 3.394 ± 1.656
6.222GluArg: 6.222 ± 1.151
4.525GluSer: 4.525 ± 1.233
2.262GluThr: 2.262 ± 1.226
7.353GluVal: 7.353 ± 2.63
1.697GluTrp: 1.697 ± 0.764
2.828GluTyr: 2.828 ± 2.174
0.0GluXaa: 0.0 ± 0.0
Phe
2.828PheAla: 2.828 ± 0.836
0.0PheCys: 0.0 ± 0.0
1.697PheAsp: 1.697 ± 0.797
2.828PheGlu: 2.828 ± 0.904
1.131PhePhe: 1.131 ± 0.597
3.959PheGly: 3.959 ± 1.724
0.566PheHis: 0.566 ± 0.416
1.131PheIle: 1.131 ± 0.615
2.262PheLys: 2.262 ± 1.187
1.697PheLeu: 1.697 ± 0.764
0.0PheMet: 0.0 ± 0.0
2.828PheAsn: 2.828 ± 1.054
1.697PhePro: 1.697 ± 1.2
1.131PheGln: 1.131 ± 0.569
1.131PheArg: 1.131 ± 0.615
1.131PheSer: 1.131 ± 0.722
0.566PheThr: 0.566 ± 0.592
2.262PheVal: 2.262 ± 0.847
1.697PheTrp: 1.697 ± 1.098
1.697PheTyr: 1.697 ± 0.859
0.0PheXaa: 0.0 ± 0.0
Gly
9.615GlyAla: 9.615 ± 2.129
0.0GlyCys: 0.0 ± 0.0
4.525GlyAsp: 4.525 ± 2.659
9.05GlyGlu: 9.05 ± 2.525
1.697GlyPhe: 1.697 ± 0.827
14.706GlyGly: 14.706 ± 4.111
1.697GlyHis: 1.697 ± 1.229
1.697GlyIle: 1.697 ± 1.353
5.09GlyLys: 5.09 ± 1.418
5.09GlyLeu: 5.09 ± 1.63
1.131GlyMet: 1.131 ± 0.597
3.959GlyAsn: 3.959 ± 1.871
3.394GlyPro: 3.394 ± 0.934
3.959GlyGln: 3.959 ± 1.449
5.09GlyArg: 5.09 ± 2.221
5.09GlySer: 5.09 ± 1.37
9.615GlyThr: 9.615 ± 2.358
6.787GlyVal: 6.787 ± 1.805
2.262GlyTrp: 2.262 ± 0.955
2.828GlyTyr: 2.828 ± 1.123
0.0GlyXaa: 0.0 ± 0.0
His
1.131HisAla: 1.131 ± 0.831
0.0HisCys: 0.0 ± 0.0
0.566HisAsp: 0.566 ± 0.416
1.697HisGlu: 1.697 ± 0.889
0.0HisPhe: 0.0 ± 0.0
2.828HisGly: 2.828 ± 1.337
0.0HisHis: 0.0 ± 0.0
1.131HisIle: 1.131 ± 0.615
1.131HisLys: 1.131 ± 0.615
2.828HisLeu: 2.828 ± 1.471
0.566HisMet: 0.566 ± 0.558
0.566HisAsn: 0.566 ± 0.416
1.131HisPro: 1.131 ± 0.814
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
1.131HisSer: 1.131 ± 1.156
0.0HisThr: 0.0 ± 0.0
1.697HisVal: 1.697 ± 0.915
2.262HisTrp: 2.262 ± 1.726
0.566HisTyr: 0.566 ± 0.558
0.0HisXaa: 0.0 ± 0.0
Ile
1.697IleAla: 1.697 ± 0.892
0.0IleCys: 0.0 ± 0.0
1.697IleAsp: 1.697 ± 1.247
2.262IleGlu: 2.262 ± 1.194
0.0IlePhe: 0.0 ± 0.0
3.394IleGly: 3.394 ± 1.016
1.697IleHis: 1.697 ± 0.764
1.697IleIle: 1.697 ± 1.102
1.131IleLys: 1.131 ± 0.597
2.828IleLeu: 2.828 ± 0.572
1.131IleMet: 1.131 ± 0.682
0.566IleAsn: 0.566 ± 0.416
2.828IlePro: 2.828 ± 0.954
1.131IleGln: 1.131 ± 0.597
2.828IleArg: 2.828 ± 2.241
0.566IleSer: 0.566 ± 0.578
2.262IleThr: 2.262 ± 1.775
2.828IleVal: 2.828 ± 1.14
1.131IleTrp: 1.131 ± 0.831
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
9.615LysAla: 9.615 ± 3.735
0.0LysCys: 0.0 ± 0.0
2.828LysAsp: 2.828 ± 1.618
1.697LysGlu: 1.697 ± 0.827
1.131LysPhe: 1.131 ± 0.682
1.697LysGly: 1.697 ± 0.789
0.566LysHis: 0.566 ± 0.416
1.131LysIle: 1.131 ± 0.746
3.394LysLys: 3.394 ± 1.082
2.262LysLeu: 2.262 ± 1.262
0.566LysMet: 0.566 ± 0.592
0.0LysAsn: 0.0 ± 0.0
5.09LysPro: 5.09 ± 1.343
2.828LysGln: 2.828 ± 1.096
3.959LysArg: 3.959 ± 1.372
1.131LysSer: 1.131 ± 0.682
2.262LysThr: 2.262 ± 1.226
2.262LysVal: 2.262 ± 0.791
0.566LysTrp: 0.566 ± 0.416
1.131LysTyr: 1.131 ± 0.814
0.0LysXaa: 0.0 ± 0.0
Leu
10.747LeuAla: 10.747 ± 1.938
0.566LeuCys: 0.566 ± 0.59
5.656LeuAsp: 5.656 ± 1.272
6.222LeuGlu: 6.222 ± 1.387
1.697LeuPhe: 1.697 ± 0.728
9.615LeuGly: 9.615 ± 1.668
2.262LeuHis: 2.262 ± 1.245
1.131LeuIle: 1.131 ± 0.764
2.828LeuLys: 2.828 ± 1.118
2.828LeuLeu: 2.828 ± 1.209
1.697LeuMet: 1.697 ± 0.841
1.697LeuAsn: 1.697 ± 0.694
2.262LeuPro: 2.262 ± 1.064
2.262LeuGln: 2.262 ± 1.292
9.05LeuArg: 9.05 ± 1.572
5.09LeuSer: 5.09 ± 2.048
2.828LeuThr: 2.828 ± 1.454
4.525LeuVal: 4.525 ± 1.843
0.566LeuTrp: 0.566 ± 0.598
0.0LeuTyr: 0.0 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
2.828MetAla: 2.828 ± 1.468
0.0MetCys: 0.0 ± 0.0
1.697MetAsp: 1.697 ± 0.859
1.131MetGlu: 1.131 ± 0.826
2.262MetPhe: 2.262 ± 1.618
2.828MetGly: 2.828 ± 1.209
0.566MetHis: 0.566 ± 0.416
0.566MetIle: 0.566 ± 0.662
0.566MetLys: 0.566 ± 0.598
1.697MetLeu: 1.697 ± 0.728
0.0MetMet: 0.0 ± 0.0
1.697MetAsn: 1.697 ± 0.841
2.262MetPro: 2.262 ± 0.631
0.566MetGln: 0.566 ± 0.578
1.131MetArg: 1.131 ± 0.831
0.566MetSer: 0.566 ± 0.558
0.566MetThr: 0.566 ± 0.416
0.566MetVal: 0.566 ± 0.416
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.697AsnAla: 1.697 ± 1.091
0.0AsnCys: 0.0 ± 0.0
1.131AsnAsp: 1.131 ± 1.197
1.131AsnGlu: 1.131 ± 0.682
1.697AsnPhe: 1.697 ± 1.247
4.525AsnGly: 4.525 ± 1.233
1.131AsnHis: 1.131 ± 0.831
1.131AsnIle: 1.131 ± 0.597
0.566AsnLys: 0.566 ± 0.578
1.697AsnLeu: 1.697 ± 0.596
0.566AsnMet: 0.566 ± 0.615
1.697AsnAsn: 1.697 ± 0.877
4.525AsnPro: 4.525 ± 1.548
0.566AsnGln: 0.566 ± 0.592
5.09AsnArg: 5.09 ± 1.394
1.697AsnSer: 1.697 ± 0.596
2.828AsnThr: 2.828 ± 1.608
3.394AsnVal: 3.394 ± 1.774
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
8.484ProAla: 8.484 ± 1.867
0.0ProCys: 0.0 ± 0.0
3.394ProAsp: 3.394 ± 1.703
5.09ProGlu: 5.09 ± 1.508
2.262ProPhe: 2.262 ± 1.663
10.181ProGly: 10.181 ± 4.282
1.131ProHis: 1.131 ± 0.757
3.394ProIle: 3.394 ± 1.255
1.697ProLys: 1.697 ± 1.193
5.09ProLeu: 5.09 ± 2.192
1.697ProMet: 1.697 ± 0.697
1.697ProAsn: 1.697 ± 0.889
2.828ProPro: 2.828 ± 1.378
3.394ProGln: 3.394 ± 1.192
3.394ProArg: 3.394 ± 1.255
6.222ProSer: 6.222 ± 1.858
2.828ProThr: 2.828 ± 1.18
3.959ProVal: 3.959 ± 1.661
1.697ProTrp: 1.697 ± 0.716
0.566ProTyr: 0.566 ± 0.598
0.0ProXaa: 0.0 ± 0.0
Gln
6.787GlnAla: 6.787 ± 1.883
0.0GlnCys: 0.0 ± 0.0
0.566GlnAsp: 0.566 ± 0.558
2.262GlnGlu: 2.262 ± 0.708
1.697GlnPhe: 1.697 ± 1.247
2.828GlnGly: 2.828 ± 1.236
1.131GlnHis: 1.131 ± 0.615
0.0GlnIle: 0.0 ± 0.0
1.697GlnLys: 1.697 ± 0.764
3.394GlnLeu: 3.394 ± 1.409
0.0GlnMet: 0.0 ± 0.0
3.394GlnAsn: 3.394 ± 1.353
5.09GlnPro: 5.09 ± 1.856
2.262GlnGln: 2.262 ± 0.92
3.959GlnArg: 3.959 ± 1.865
3.394GlnSer: 3.394 ± 1.248
3.394GlnThr: 3.394 ± 0.924
3.394GlnVal: 3.394 ± 1.199
0.0GlnTrp: 0.0 ± 0.0
1.131GlnTyr: 1.131 ± 0.704
0.0GlnXaa: 0.0 ± 0.0
Arg
10.181ArgAla: 10.181 ± 2.282
0.0ArgCys: 0.0 ± 0.0
3.959ArgAsp: 3.959 ± 1.492
5.656ArgGlu: 5.656 ± 1.711
3.394ArgPhe: 3.394 ± 1.509
4.525ArgGly: 4.525 ± 1.122
0.566ArgHis: 0.566 ± 0.558
2.828ArgIle: 2.828 ± 1.608
2.262ArgLys: 2.262 ± 1.311
9.05ArgLeu: 9.05 ± 1.543
1.131ArgMet: 1.131 ± 0.632
2.262ArgAsn: 2.262 ± 0.705
2.828ArgPro: 2.828 ± 0.967
6.787ArgGln: 6.787 ± 0.757
6.787ArgArg: 6.787 ± 2.635
3.959ArgSer: 3.959 ± 1.008
3.394ArgThr: 3.394 ± 1.692
1.697ArgVal: 1.697 ± 0.784
1.131ArgTrp: 1.131 ± 0.826
1.697ArgTyr: 1.697 ± 1.098
0.0ArgXaa: 0.0 ± 0.0
Ser
5.656SerAla: 5.656 ± 2.707
0.0SerCys: 0.0 ± 0.0
4.525SerAsp: 4.525 ± 1.411
2.828SerGlu: 2.828 ± 1.118
2.262SerPhe: 2.262 ± 1.14
5.09SerGly: 5.09 ± 1.197
1.131SerHis: 1.131 ± 0.615
1.131SerIle: 1.131 ± 0.831
2.262SerLys: 2.262 ± 0.805
2.828SerLeu: 2.828 ± 1.28
2.262SerMet: 2.262 ± 0.674
1.131SerAsn: 1.131 ± 0.746
0.566SerPro: 0.566 ± 0.416
2.828SerGln: 2.828 ± 1.321
2.828SerArg: 2.828 ± 1.176
3.959SerSer: 3.959 ± 1.322
2.828SerThr: 2.828 ± 0.716
5.09SerVal: 5.09 ± 2.378
2.262SerTrp: 2.262 ± 1.467
2.262SerTyr: 2.262 ± 1.024
0.0SerXaa: 0.0 ± 0.0
Thr
7.353ThrAla: 7.353 ± 1.765
0.0ThrCys: 0.0 ± 0.0
4.525ThrAsp: 4.525 ± 2.371
3.394ThrGlu: 3.394 ± 1.525
2.262ThrPhe: 2.262 ± 1.23
4.525ThrGly: 4.525 ± 1.903
0.0ThrHis: 0.0 ± 0.0
0.566ThrIle: 0.566 ± 0.59
1.131ThrLys: 1.131 ± 0.615
5.656ThrLeu: 5.656 ± 1.443
0.0ThrMet: 0.0 ± 0.0
3.394ThrAsn: 3.394 ± 1.231
3.959ThrPro: 3.959 ± 1.088
3.959ThrGln: 3.959 ± 1.514
1.697ThrArg: 1.697 ± 0.712
2.828ThrSer: 2.828 ± 1.049
4.525ThrThr: 4.525 ± 2.462
3.959ThrVal: 3.959 ± 2.405
2.828ThrTrp: 2.828 ± 1.397
0.566ThrTyr: 0.566 ± 0.558
0.0ThrXaa: 0.0 ± 0.0
Val
2.828ValAla: 2.828 ± 1.051
0.566ValCys: 0.566 ± 0.578
3.959ValAsp: 3.959 ± 1.464
4.525ValGlu: 4.525 ± 1.765
1.697ValPhe: 1.697 ± 1.114
6.787ValGly: 6.787 ± 1.702
1.131ValHis: 1.131 ± 0.615
4.525ValIle: 4.525 ± 1.789
3.394ValLys: 3.394 ± 0.883
2.262ValLeu: 2.262 ± 1.137
3.394ValMet: 3.394 ± 1.558
5.09ValAsn: 5.09 ± 1.57
5.09ValPro: 5.09 ± 2.023
3.394ValGln: 3.394 ± 1.677
3.394ValArg: 3.394 ± 0.966
3.394ValSer: 3.394 ± 1.481
4.525ValThr: 4.525 ± 1.623
7.919ValVal: 7.919 ± 1.889
1.131ValTrp: 1.131 ± 0.569
1.131ValTyr: 1.131 ± 0.615
0.0ValXaa: 0.0 ± 0.0
Trp
3.394TrpAla: 3.394 ± 1.656
0.566TrpCys: 0.566 ± 0.578
1.131TrpAsp: 1.131 ± 0.814
1.131TrpGlu: 1.131 ± 0.814
0.566TrpPhe: 0.566 ± 0.598
1.697TrpGly: 1.697 ± 1.243
0.566TrpHis: 0.566 ± 0.558
0.0TrpIle: 0.0 ± 0.0
1.697TrpLys: 1.697 ± 0.981
1.697TrpLeu: 1.697 ± 1.15
0.566TrpMet: 0.566 ± 0.501
0.566TrpAsn: 0.566 ± 0.416
1.697TrpPro: 1.697 ± 1.098
1.131TrpGln: 1.131 ± 0.615
3.394TrpArg: 3.394 ± 1.654
0.566TrpSer: 0.566 ± 0.598
1.697TrpThr: 1.697 ± 0.759
0.566TrpVal: 0.566 ± 0.416
0.566TrpTrp: 0.566 ± 0.558
0.566TrpTyr: 0.566 ± 0.598
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.697TyrAla: 1.697 ± 0.889
0.0TyrCys: 0.0 ± 0.0
2.262TyrAsp: 2.262 ± 0.837
1.131TyrGlu: 1.131 ± 0.796
1.697TyrPhe: 1.697 ± 1.147
2.262TyrGly: 2.262 ± 1.192
0.0TyrHis: 0.0 ± 0.0
1.131TyrIle: 1.131 ± 0.615
1.131TyrLys: 1.131 ± 0.569
2.828TyrLeu: 2.828 ± 1.054
0.566TyrMet: 0.566 ± 0.416
1.697TyrAsn: 1.697 ± 1.091
0.0TyrPro: 0.0 ± 0.0
0.566TyrGln: 0.566 ± 0.598
1.131TyrArg: 1.131 ± 0.796
1.131TyrSer: 1.131 ± 1.115
1.131TyrThr: 1.131 ± 1.115
1.131TyrVal: 1.131 ± 1.115
0.566TyrTrp: 0.566 ± 0.558
0.566TyrTyr: 0.566 ± 0.558
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1769 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski