Amino acid dipepetide frequency for Anaerofustis stercorihominis DSM 17244

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.791AlaAla: 3.791 ± 0.102
0.776AlaCys: 0.776 ± 0.044
3.276AlaAsp: 3.276 ± 0.083
3.199AlaGlu: 3.199 ± 0.087
2.651AlaPhe: 2.651 ± 0.071
4.425AlaGly: 4.425 ± 0.083
0.82AlaHis: 0.82 ± 0.034
4.571AlaIle: 4.571 ± 0.084
5.251AlaLys: 5.251 ± 0.111
5.417AlaLeu: 5.417 ± 0.095
1.692AlaMet: 1.692 ± 0.058
2.692AlaAsn: 2.692 ± 0.067
1.33AlaPro: 1.33 ± 0.048
1.135AlaGln: 1.135 ± 0.053
1.789AlaArg: 1.789 ± 0.055
3.539AlaSer: 3.539 ± 0.078
2.737AlaThr: 2.737 ± 0.08
4.835AlaVal: 4.835 ± 0.11
0.284AlaTrp: 0.284 ± 0.024
2.102AlaTyr: 2.102 ± 0.063
0.0AlaXaa: 0.0 ± 0.0
Cys
0.826CysAla: 0.826 ± 0.034
0.154CysCys: 0.154 ± 0.016
0.766CysAsp: 0.766 ± 0.033
0.794CysGlu: 0.794 ± 0.04
0.595CysPhe: 0.595 ± 0.032
1.214CysGly: 1.214 ± 0.047
0.225CysHis: 0.225 ± 0.02
1.096CysIle: 1.096 ± 0.051
0.984CysLys: 0.984 ± 0.046
0.943CysLeu: 0.943 ± 0.034
0.336CysMet: 0.336 ± 0.026
0.554CysAsn: 0.554 ± 0.028
0.525CysPro: 0.525 ± 0.034
0.192CysGln: 0.192 ± 0.02
0.353CysArg: 0.353 ± 0.024
0.961CysSer: 0.961 ± 0.048
0.654CysThr: 0.654 ± 0.043
0.778CysVal: 0.778 ± 0.036
0.054CysTrp: 0.054 ± 0.009
0.487CysTyr: 0.487 ± 0.031
0.0CysXaa: 0.0 ± 0.0
Asp
2.762AspAla: 2.762 ± 0.069
0.623AspCys: 0.623 ± 0.033
3.588AspAsp: 3.588 ± 0.089
5.385AspGlu: 5.385 ± 0.105
3.285AspPhe: 3.285 ± 0.078
3.57AspGly: 3.57 ± 0.079
0.625AspHis: 0.625 ± 0.027
7.197AspIle: 7.197 ± 0.116
6.646AspLys: 6.646 ± 0.113
5.513AspLeu: 5.513 ± 0.093
1.908AspMet: 1.908 ± 0.056
4.042AspAsn: 4.042 ± 0.089
1.303AspPro: 1.303 ± 0.048
0.616AspGln: 0.616 ± 0.034
1.879AspArg: 1.879 ± 0.053
3.172AspSer: 3.172 ± 0.08
3.206AspThr: 3.206 ± 0.068
4.016AspVal: 4.016 ± 0.082
0.288AspTrp: 0.288 ± 0.024
3.237AspTyr: 3.237 ± 0.079
0.0AspXaa: 0.0 ± 0.0
Glu
4.335GluAla: 4.335 ± 0.103
0.808GluCys: 0.808 ± 0.039
5.015GluAsp: 5.015 ± 0.101
7.068GluGlu: 7.068 ± 0.148
2.851GluPhe: 2.851 ± 0.071
4.004GluGly: 4.004 ± 0.083
1.198GluHis: 1.198 ± 0.062
6.613GluIle: 6.613 ± 0.108
7.197GluLys: 7.197 ± 0.119
6.077GluLeu: 6.077 ± 0.1
2.109GluMet: 2.109 ± 0.062
5.569GluAsn: 5.569 ± 0.106
1.323GluPro: 1.323 ± 0.054
1.646GluGln: 1.646 ± 0.057
2.445GluArg: 2.445 ± 0.075
3.008GluSer: 3.008 ± 0.064
3.073GluThr: 3.073 ± 0.075
4.832GluVal: 4.832 ± 0.087
0.288GluTrp: 0.288 ± 0.021
3.213GluTyr: 3.213 ± 0.079
0.0GluXaa: 0.0 ± 0.0
Phe
2.488PheAla: 2.488 ± 0.064
0.586PheCys: 0.586 ± 0.031
3.144PheAsp: 3.144 ± 0.074
2.928PheGlu: 2.928 ± 0.074
2.046PhePhe: 2.046 ± 0.078
2.846PheGly: 2.846 ± 0.075
0.555PheHis: 0.555 ± 0.03
4.599PheIle: 4.599 ± 0.123
3.736PheLys: 3.736 ± 0.075
3.978PheLeu: 3.978 ± 0.097
1.318PheMet: 1.318 ± 0.043
2.565PheAsn: 2.565 ± 0.065
1.138PhePro: 1.138 ± 0.041
0.649PheGln: 0.649 ± 0.033
1.191PheArg: 1.191 ± 0.04
3.197PheSer: 3.197 ± 0.079
2.488PheThr: 2.488 ± 0.069
2.698PheVal: 2.698 ± 0.082
0.206PheTrp: 0.206 ± 0.017
1.923PheTyr: 1.923 ± 0.06
0.0PheXaa: 0.0 ± 0.0
Gly
4.158GlyAla: 4.158 ± 0.092
0.978GlyCys: 0.978 ± 0.041
3.246GlyAsp: 3.246 ± 0.07
4.092GlyGlu: 4.092 ± 0.091
3.163GlyPhe: 3.163 ± 0.074
4.531GlyGly: 4.531 ± 0.111
1.046GlyHis: 1.046 ± 0.046
6.227GlyIle: 6.227 ± 0.089
5.793GlyLys: 5.793 ± 0.091
5.532GlyLeu: 5.532 ± 0.104
1.858GlyMet: 1.858 ± 0.061
3.246GlyAsn: 3.246 ± 0.082
1.179GlyPro: 1.179 ± 0.076
1.232GlyGln: 1.232 ± 0.04
2.25GlyArg: 2.25 ± 0.066
4.252GlySer: 4.252 ± 0.079
3.441GlyThr: 3.441 ± 0.078
4.795GlyVal: 4.795 ± 0.095
0.362GlyTrp: 0.362 ± 0.029
3.185GlyTyr: 3.185 ± 0.066
0.0GlyXaa: 0.0 ± 0.0
His
0.728HisAla: 0.728 ± 0.033
0.244HisCys: 0.244 ± 0.022
0.82HisAsp: 0.82 ± 0.04
0.946HisGlu: 0.946 ± 0.056
0.69HisPhe: 0.69 ± 0.036
0.996HisGly: 0.996 ± 0.041
0.36HisHis: 0.36 ± 0.052
1.363HisIle: 1.363 ± 0.045
1.076HisLys: 1.076 ± 0.037
1.253HisLeu: 1.253 ± 0.044
0.387HisMet: 0.387 ± 0.026
0.711HisAsn: 0.711 ± 0.032
0.633HisPro: 0.633 ± 0.032
0.28HisGln: 0.28 ± 0.019
0.533HisArg: 0.533 ± 0.03
0.858HisSer: 0.858 ± 0.034
0.782HisThr: 0.782 ± 0.033
0.788HisVal: 0.788 ± 0.034
0.104HisTrp: 0.104 ± 0.011
0.628HisTyr: 0.628 ± 0.031
0.0HisXaa: 0.0 ± 0.0
Ile
5.26IleAla: 5.26 ± 0.096
1.359IleCys: 1.359 ± 0.049
6.059IleAsp: 6.059 ± 0.107
6.153IleGlu: 6.153 ± 0.106
3.974IlePhe: 3.974 ± 0.1
5.803IleGly: 5.803 ± 0.113
1.192IleHis: 1.192 ± 0.041
8.876IleIle: 8.876 ± 0.16
9.256IleLys: 9.256 ± 0.137
8.577IleLeu: 8.577 ± 0.171
2.352IleMet: 2.352 ± 0.072
6.142IleAsn: 6.142 ± 0.125
3.208IlePro: 3.208 ± 0.072
1.454IleGln: 1.454 ± 0.05
2.812IleArg: 2.812 ± 0.069
6.705IleSer: 6.705 ± 0.12
4.986IleThr: 4.986 ± 0.093
5.582IleVal: 5.582 ± 0.098
0.437IleTrp: 0.437 ± 0.025
3.632IleTyr: 3.632 ± 0.088
0.0IleXaa: 0.0 ± 0.0
Lys
5.183LysAla: 5.183 ± 0.098
0.922LysCys: 0.922 ± 0.039
6.912LysAsp: 6.912 ± 0.114
9.774LysGlu: 9.774 ± 0.132
2.84LysPhe: 2.84 ± 0.067
5.602LysGly: 5.602 ± 0.099
1.218LysHis: 1.218 ± 0.048
8.079LysIle: 8.079 ± 0.119
9.669LysLys: 9.669 ± 0.167
7.127LysLeu: 7.127 ± 0.116
2.851LysMet: 2.851 ± 0.089
6.697LysAsn: 6.697 ± 0.115
2.05LysPro: 2.05 ± 0.058
2.032LysGln: 2.032 ± 0.061
3.287LysArg: 3.287 ± 0.075
5.572LysSer: 5.572 ± 0.106
4.582LysThr: 4.582 ± 0.093
6.28LysVal: 6.28 ± 0.122
0.514LysTrp: 0.514 ± 0.026
4.543LysTyr: 4.543 ± 0.105
0.0LysXaa: 0.0 ± 0.0
Leu
4.717LeuAla: 4.717 ± 0.098
1.212LeuCys: 1.212 ± 0.045
5.301LeuAsp: 5.301 ± 0.095
5.334LeuGlu: 5.334 ± 0.108
4.158LeuPhe: 4.158 ± 0.105
5.532LeuGly: 5.532 ± 0.102
1.127LeuHis: 1.127 ± 0.037
8.058LeuIle: 8.058 ± 0.15
8.537LeuLys: 8.537 ± 0.121
7.457LeuLeu: 7.457 ± 0.139
2.374LeuMet: 2.374 ± 0.055
5.96LeuAsn: 5.96 ± 0.095
2.654LeuPro: 2.654 ± 0.065
1.498LeuGln: 1.498 ± 0.053
2.901LeuArg: 2.901 ± 0.071
6.929LeuSer: 6.929 ± 0.112
4.591LeuThr: 4.591 ± 0.08
4.63LeuVal: 4.63 ± 0.086
0.493LeuTrp: 0.493 ± 0.03
3.468LeuTyr: 3.468 ± 0.08
0.0LeuXaa: 0.0 ± 0.0
Met
1.675MetAla: 1.675 ± 0.045
0.348MetCys: 0.348 ± 0.024
1.89MetAsp: 1.89 ± 0.054
2.035MetGlu: 2.035 ± 0.058
1.18MetPhe: 1.18 ± 0.049
1.931MetGly: 1.931 ± 0.057
0.354MetHis: 0.354 ± 0.024
2.4MetIle: 2.4 ± 0.066
2.597MetLys: 2.597 ± 0.069
2.444MetLeu: 2.444 ± 0.069
0.728MetMet: 0.728 ± 0.04
1.872MetAsn: 1.872 ± 0.051
0.926MetPro: 0.926 ± 0.038
0.648MetGln: 0.648 ± 0.038
0.757MetArg: 0.757 ± 0.037
1.926MetSer: 1.926 ± 0.06
1.374MetThr: 1.374 ± 0.049
1.633MetVal: 1.633 ± 0.054
0.138MetTrp: 0.138 ± 0.015
0.923MetTyr: 0.923 ± 0.041
0.0MetXaa: 0.0 ± 0.0
Asn
3.399AsnAla: 3.399 ± 0.078
0.611AsnCys: 0.611 ± 0.035
3.84AsnAsp: 3.84 ± 0.083
4.59AsnGlu: 4.59 ± 0.085
2.276AsnPhe: 2.276 ± 0.067
3.576AsnGly: 3.576 ± 0.085
0.861AsnHis: 0.861 ± 0.041
6.894AsnIle: 6.894 ± 0.117
6.962AsnLys: 6.962 ± 0.13
4.913AsnLeu: 4.913 ± 0.087
1.807AsnMet: 1.807 ± 0.052
4.316AsnAsn: 4.316 ± 0.1
1.891AsnPro: 1.891 ± 0.06
1.147AsnGln: 1.147 ± 0.042
1.902AsnArg: 1.902 ± 0.057
3.517AsnSer: 3.517 ± 0.08
2.952AsnThr: 2.952 ± 0.079
3.874AsnVal: 3.874 ± 0.076
0.3AsnTrp: 0.3 ± 0.023
2.538AsnTyr: 2.538 ± 0.074
0.0AsnXaa: 0.0 ± 0.0
Pro
1.468ProAla: 1.468 ± 0.054
0.35ProCys: 0.35 ± 0.023
1.625ProAsp: 1.625 ± 0.06
1.858ProGlu: 1.858 ± 0.061
1.403ProPhe: 1.403 ± 0.051
1.61ProGly: 1.61 ± 0.047
0.419ProHis: 0.419 ± 0.022
2.551ProIle: 2.551 ± 0.066
2.282ProLys: 2.282 ± 0.055
2.415ProLeu: 2.415 ± 0.06
0.751ProMet: 0.751 ± 0.03
1.433ProAsn: 1.433 ± 0.056
0.569ProPro: 0.569 ± 0.031
0.555ProGln: 0.555 ± 0.033
0.719ProArg: 0.719 ± 0.036
1.822ProSer: 1.822 ± 0.07
1.481ProThr: 1.481 ± 0.069
2.014ProVal: 2.014 ± 0.054
0.186ProTrp: 0.186 ± 0.016
1.386ProTyr: 1.386 ± 0.047
0.0ProXaa: 0.0 ± 0.0
Gln
1.186GlnAla: 1.186 ± 0.052
0.215GlnCys: 0.215 ± 0.017
0.987GlnAsp: 0.987 ± 0.039
1.139GlnGlu: 1.139 ± 0.047
0.711GlnPhe: 0.711 ± 0.031
1.242GlnGly: 1.242 ± 0.054
0.242GlnHis: 0.242 ± 0.019
1.931GlnIle: 1.931 ± 0.058
1.724GlnLys: 1.724 ± 0.05
1.481GlnLeu: 1.481 ± 0.047
0.669GlnMet: 0.669 ± 0.032
1.323GlnAsn: 1.323 ± 0.048
0.462GlnPro: 0.462 ± 0.027
0.462GlnGln: 0.462 ± 0.033
0.82GlnArg: 0.82 ± 0.035
1.198GlnSer: 1.198 ± 0.041
0.976GlnThr: 0.976 ± 0.041
1.156GlnVal: 1.156 ± 0.047
0.159GlnTrp: 0.159 ± 0.016
0.663GlnTyr: 0.663 ± 0.034
0.0GlnXaa: 0.0 ± 0.0
Arg
1.669ArgAla: 1.669 ± 0.052
0.404ArgCys: 0.404 ± 0.025
1.837ArgAsp: 1.837 ± 0.055
2.907ArgGlu: 2.907 ± 0.08
1.327ArgPhe: 1.327 ± 0.045
2.028ArgGly: 2.028 ± 0.065
0.505ArgHis: 0.505 ± 0.031
2.641ArgIle: 2.641 ± 0.067
3.063ArgLys: 3.063 ± 0.079
2.753ArgLeu: 2.753 ± 0.068
0.897ArgMet: 0.897 ± 0.037
1.843ArgAsn: 1.843 ± 0.053
0.968ArgPro: 0.968 ± 0.041
0.831ArgGln: 0.831 ± 0.045
1.35ArgArg: 1.35 ± 0.055
1.683ArgSer: 1.683 ± 0.054
1.562ArgThr: 1.562 ± 0.051
2.081ArgVal: 2.081 ± 0.062
0.173ArgTrp: 0.173 ± 0.018
1.41ArgTyr: 1.41 ± 0.048
0.0ArgXaa: 0.0 ± 0.0
Ser
3.558SerAla: 3.558 ± 0.081
0.652SerCys: 0.652 ± 0.035
4.021SerAsp: 4.021 ± 0.084
4.334SerGlu: 4.334 ± 0.088
3.241SerPhe: 3.241 ± 0.091
4.809SerGly: 4.809 ± 0.086
0.914SerHis: 0.914 ± 0.043
5.788SerIle: 5.788 ± 0.098
5.684SerLys: 5.684 ± 0.116
5.868SerLeu: 5.868 ± 0.098
1.689SerMet: 1.689 ± 0.053
3.42SerAsn: 3.42 ± 0.084
1.551SerPro: 1.551 ± 0.057
1.235SerGln: 1.235 ± 0.051
2.025SerArg: 2.025 ± 0.056
4.565SerSer: 4.565 ± 0.107
3.152SerThr: 3.152 ± 0.082
4.465SerVal: 4.465 ± 0.094
0.378SerTrp: 0.378 ± 0.025
2.707SerTyr: 2.707 ± 0.073
0.0SerXaa: 0.0 ± 0.0
Thr
3.101ThrAla: 3.101 ± 0.079
0.666ThrCys: 0.666 ± 0.042
2.96ThrAsp: 2.96 ± 0.065
2.645ThrGlu: 2.645 ± 0.069
2.501ThrPhe: 2.501 ± 0.069
3.712ThrGly: 3.712 ± 0.123
0.82ThrHis: 0.82 ± 0.037
4.426ThrIle: 4.426 ± 0.086
4.555ThrLys: 4.555 ± 0.088
4.968ThrLeu: 4.968 ± 0.092
1.153ThrMet: 1.153 ± 0.04
2.762ThrAsn: 2.762 ± 0.057
1.902ThrPro: 1.902 ± 0.055
1.014ThrGln: 1.014 ± 0.042
1.422ThrArg: 1.422 ± 0.043
3.406ThrSer: 3.406 ± 0.085
2.771ThrThr: 2.771 ± 0.078
3.645ThrVal: 3.645 ± 0.088
0.265ThrTrp: 0.265 ± 0.021
2.262ThrTyr: 2.262 ± 0.066
0.0ThrXaa: 0.0 ± 0.0
Val
3.382ValAla: 3.382 ± 0.08
1.024ValCys: 1.024 ± 0.041
4.081ValAsp: 4.081 ± 0.093
3.987ValGlu: 3.987 ± 0.088
3.058ValPhe: 3.058 ± 0.072
4.093ValGly: 4.093 ± 0.085
0.885ValHis: 0.885 ± 0.034
6.184ValIle: 6.184 ± 0.115
6.177ValLys: 6.177 ± 0.111
5.951ValLeu: 5.951 ± 0.108
1.778ValMet: 1.778 ± 0.057
3.845ValAsn: 3.845 ± 0.077
1.911ValPro: 1.911 ± 0.056
1.144ValGln: 1.144 ± 0.051
2.035ValArg: 2.035 ± 0.058
4.591ValSer: 4.591 ± 0.084
3.654ValThr: 3.654 ± 0.085
4.332ValVal: 4.332 ± 0.107
0.359ValTrp: 0.359 ± 0.027
2.618ValTyr: 2.618 ± 0.062
0.0ValXaa: 0.0 ± 0.0
Trp
0.31TrpAla: 0.31 ± 0.023
0.076TrpCys: 0.076 ± 0.011
0.365TrpAsp: 0.365 ± 0.021
0.421TrpGlu: 0.421 ± 0.025
0.259TrpPhe: 0.259 ± 0.02
0.365TrpGly: 0.365 ± 0.022
0.136TrpHis: 0.136 ± 0.016
0.477TrpIle: 0.477 ± 0.029
0.353TrpLys: 0.353 ± 0.026
0.452TrpLeu: 0.452 ± 0.028
0.145TrpMet: 0.145 ± 0.015
0.31TrpAsn: 0.31 ± 0.024
0.079TrpPro: 0.079 ± 0.01
0.157TrpGln: 0.157 ± 0.018
0.171TrpArg: 0.171 ± 0.015
0.307TrpSer: 0.307 ± 0.022
0.268TrpThr: 0.268 ± 0.025
0.31TrpVal: 0.31 ± 0.02
0.044TrpTrp: 0.044 ± 0.008
0.235TrpTyr: 0.235 ± 0.022
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.318TyrAla: 2.318 ± 0.057
0.483TyrCys: 0.483 ± 0.026
3.128TyrAsp: 3.128 ± 0.075
3.082TyrGlu: 3.082 ± 0.083
2.07TyrPhe: 2.07 ± 0.066
2.677TyrGly: 2.677 ± 0.064
0.675TyrHis: 0.675 ± 0.033
3.848TyrIle: 3.848 ± 0.083
4.196TyrLys: 4.196 ± 0.088
3.813TyrLeu: 3.813 ± 0.088
0.974TyrMet: 0.974 ± 0.04
2.864TyrAsn: 2.864 ± 0.075
1.295TyrPro: 1.295 ± 0.047
0.819TyrGln: 0.819 ± 0.034
1.291TyrArg: 1.291 ± 0.045
2.846TyrSer: 2.846 ± 0.067
2.224TyrThr: 2.224 ± 0.07
2.347TyrVal: 2.347 ± 0.06
0.207TyrTrp: 0.207 ± 0.017
2.144TyrTyr: 2.144 ± 0.068
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2331 proteins (660854 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski