Amino acid dipepetide frequency for Kitasatospora cheerisanensis KCTC 2395

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	25.782AlaAla: 25.782 ± 0.213	1.103AlaCys: 1.103 ± 0.023	9.073AlaAsp: 9.073 ± 0.073	9.577AlaGlu: 9.577 ± 0.116	3.55AlaPhe: 3.55 ± 0.043	14.865AlaGly: 14.865 ± 0.101	3.027AlaHis: 3.027 ± 0.041	3.218AlaIle: 3.218 ± 0.039	2.654AlaLys: 2.654 ± 0.042	15.375AlaLeu: 15.375 ± 0.117	2.345AlaMet: 2.345 ± 0.036	2.088AlaAsn: 2.088 ± 0.039	8.074AlaPro: 8.074 ± 0.09	3.909AlaGln: 3.909 ± 0.046	11.035AlaArg: 11.035 ± 0.097	5.543AlaSer: 5.543 ± 0.061	7.098AlaThr: 7.098 ± 0.067	13.001AlaVal: 13.001 ± 0.097	1.878AlaTrp: 1.878 ± 0.028	2.465AlaTyr: 2.465 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	1.146CysAla: 1.146 ± 0.023	0.154CysCys: 0.154 ± 0.01	0.444CysAsp: 0.444 ± 0.016	0.377CysGlu: 0.377 ± 0.015	0.218CysPhe: 0.218 ± 0.01	1.021CysGly: 1.021 ± 0.022	0.216CysHis: 0.216 ± 0.011	0.155CysIle: 0.155 ± 0.008	0.097CysLys: 0.097 ± 0.006	0.762CysLeu: 0.762 ± 0.016	0.135CysMet: 0.135 ± 0.007	0.128CysAsn: 0.128 ± 0.008	0.624CysPro: 0.624 ± 0.019	0.171CysGln: 0.171 ± 0.008	0.731CysArg: 0.731 ± 0.02	0.555CysSer: 0.555 ± 0.018	0.574CysThr: 0.574 ± 0.018	0.542CysVal: 0.542 ± 0.016	0.167CysTrp: 0.167 ± 0.008	0.158CysTyr: 0.158 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	7.538AspAla: 7.538 ± 0.075	0.436AspCys: 0.436 ± 0.014	2.906AspAsp: 2.906 ± 0.046	3.243AspGlu: 3.243 ± 0.044	1.431AspPhe: 1.431 ± 0.024	6.712AspGly: 6.712 ± 0.068	1.444AspHis: 1.444 ± 0.027	1.339AspIle: 1.339 ± 0.025	0.884AspLys: 0.884 ± 0.025	6.328AspLeu: 6.328 ± 0.054	0.612AspMet: 0.612 ± 0.018	0.881AspAsn: 0.881 ± 0.021	4.822AspPro: 4.822 ± 0.046	1.643AspGln: 1.643 ± 0.029	5.575AspArg: 5.575 ± 0.065	2.3AspSer: 2.3 ± 0.032	2.903AspThr: 2.903 ± 0.04	3.871AspVal: 3.871 ± 0.047	1.0AspTrp: 1.0 ± 0.023	0.993AspTyr: 0.993 ± 0.021	0.0AspXaa: 0.0 ± 0.0
Glu	6.709GluAla: 6.709 ± 0.086	0.32GluCys: 0.32 ± 0.014	2.609GluAsp: 2.609 ± 0.034	3.021GluGlu: 3.021 ± 0.05	1.531GluPhe: 1.531 ± 0.026	3.619GluGly: 3.619 ± 0.048	1.562GluHis: 1.562 ± 0.027	1.896GluIle: 1.896 ± 0.032	1.05GluLys: 1.05 ± 0.025	7.382GluLeu: 7.382 ± 0.071	0.692GluMet: 0.692 ± 0.02	0.9GluAsn: 0.9 ± 0.021	3.255GluPro: 3.255 ± 0.048	2.583GluGln: 2.583 ± 0.04	5.215GluArg: 5.215 ± 0.058	2.232GluSer: 2.232 ± 0.037	2.476GluThr: 2.476 ± 0.034	4.08GluVal: 4.08 ± 0.047	0.685GluTrp: 0.685 ± 0.018	0.991GluTyr: 0.991 ± 0.022	0.0GluXaa: 0.0 ± 0.0
Phe	3.686PheAla: 3.686 ± 0.043	0.257PheCys: 0.257 ± 0.013	1.835PheAsp: 1.835 ± 0.025	1.305PheGlu: 1.305 ± 0.029	0.759PhePhe: 0.759 ± 0.022	2.99PheGly: 2.99 ± 0.038	0.615PheHis: 0.615 ± 0.016	0.554PheIle: 0.554 ± 0.014	0.41PheLys: 0.41 ± 0.015	2.441PheLeu: 2.441 ± 0.035	0.334PheMet: 0.334 ± 0.014	0.517PheAsn: 0.517 ± 0.018	1.35PhePro: 1.35 ± 0.026	0.662PheGln: 0.662 ± 0.019	1.782PheArg: 1.782 ± 0.03	1.259PheSer: 1.259 ± 0.023	1.867PheThr: 1.867 ± 0.028	1.975PheVal: 1.975 ± 0.031	0.384PheTrp: 0.384 ± 0.012	0.486PheTyr: 0.486 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	11.902GlyAla: 11.902 ± 0.099	0.981GlyCys: 0.981 ± 0.021	4.846GlyAsp: 4.846 ± 0.05	4.945GlyGlu: 4.945 ± 0.05	2.673GlyPhe: 2.673 ± 0.041	9.704GlyGly: 9.704 ± 0.121	2.459GlyHis: 2.459 ± 0.033	3.029GlyIle: 3.029 ± 0.046	2.024GlyLys: 2.024 ± 0.04	9.86GlyLeu: 9.86 ± 0.069	1.849GlyMet: 1.849 ± 0.029	1.706GlyAsn: 1.706 ± 0.036	6.257GlyPro: 6.257 ± 0.072	2.908GlyGln: 2.908 ± 0.047	9.42GlyArg: 9.42 ± 0.098	5.428GlySer: 5.428 ± 0.065	6.198GlyThr: 6.198 ± 0.076	7.237GlyVal: 7.237 ± 0.069	1.91GlyTrp: 1.91 ± 0.033	2.225GlyTyr: 2.225 ± 0.033	0.0GlyXaa: 0.0 ± 0.0
His	2.759HisAla: 2.759 ± 0.039	0.248HisCys: 0.248 ± 0.01	1.274HisAsp: 1.274 ± 0.025	1.084HisGlu: 1.084 ± 0.025	0.595HisPhe: 0.595 ± 0.015	2.51HisGly: 2.51 ± 0.036	0.808HisHis: 0.808 ± 0.023	0.479HisIle: 0.479 ± 0.013	0.283HisLys: 0.283 ± 0.011	2.773HisLeu: 2.773 ± 0.042	0.26HisMet: 0.26 ± 0.011	0.363HisAsn: 0.363 ± 0.012	2.198HisPro: 2.198 ± 0.035	0.75HisGln: 0.75 ± 0.018	2.911HisArg: 2.911 ± 0.046	0.999HisSer: 0.999 ± 0.024	1.249HisThr: 1.249 ± 0.021	1.463HisVal: 1.463 ± 0.03	0.422HisTrp: 0.422 ± 0.013	0.471HisTyr: 0.471 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	4.336IleAla: 4.336 ± 0.045	0.268IleCys: 0.268 ± 0.011	2.022IleAsp: 2.022 ± 0.035	1.663IleGlu: 1.663 ± 0.027	0.555IlePhe: 0.555 ± 0.015	3.36IleGly: 3.36 ± 0.046	0.521IleHis: 0.521 ± 0.015	0.643IleIle: 0.643 ± 0.02	0.57IleLys: 0.57 ± 0.018	2.012IleLeu: 2.012 ± 0.037	0.351IleMet: 0.351 ± 0.01	0.601IleAsn: 0.601 ± 0.016	1.51IlePro: 1.51 ± 0.028	0.611IleGln: 0.611 ± 0.017	2.008IleArg: 2.008 ± 0.032	1.45IleSer: 1.45 ± 0.028	1.963IleThr: 1.963 ± 0.032	2.178IleVal: 2.178 ± 0.036	0.35IleTrp: 0.35 ± 0.013	0.424IleTyr: 0.424 ± 0.013	0.0IleXaa: 0.0 ± 0.0
Lys	2.511LysAla: 2.511 ± 0.042	0.106LysCys: 0.106 ± 0.007	1.043LysAsp: 1.043 ± 0.027	0.855LysGlu: 0.855 ± 0.022	0.401LysPhe: 0.401 ± 0.013	1.403LysGly: 1.403 ± 0.035	0.393LysHis: 0.393 ± 0.012	0.672LysIle: 0.672 ± 0.019	0.561LysLys: 0.561 ± 0.021	1.777LysLeu: 1.777 ± 0.031	0.323LysMet: 0.323 ± 0.013	0.426LysAsn: 0.426 ± 0.017	1.15LysPro: 1.15 ± 0.025	0.623LysGln: 0.623 ± 0.016	1.119LysArg: 1.119 ± 0.028	0.951LysSer: 0.951 ± 0.023	0.984LysThr: 0.984 ± 0.026	1.583LysVal: 1.583 ± 0.033	0.209LysTrp: 0.209 ± 0.009	0.408LysTyr: 0.408 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	17.369LeuAla: 17.369 ± 0.122	0.813LeuCys: 0.813 ± 0.021	6.807LeuAsp: 6.807 ± 0.059	4.345LeuGlu: 4.345 ± 0.048	2.506LeuPhe: 2.506 ± 0.037	9.709LeuGly: 9.709 ± 0.065	2.502LeuHis: 2.502 ± 0.032	3.031LeuIle: 3.031 ± 0.043	1.635LeuLys: 1.635 ± 0.035	12.337LeuLeu: 12.337 ± 0.115	1.456LeuMet: 1.456 ± 0.024	1.688LeuAsn: 1.688 ± 0.029	7.375LeuPro: 7.375 ± 0.067	2.197LeuGln: 2.197 ± 0.034	9.155LeuArg: 9.155 ± 0.084	4.96LeuSer: 4.96 ± 0.049	6.974LeuThr: 6.974 ± 0.061	8.749LeuVal: 8.749 ± 0.066	1.311LeuTrp: 1.311 ± 0.028	1.716LeuTyr: 1.716 ± 0.033	0.0LeuXaa: 0.0 ± 0.0
Met	2.071MetAla: 2.071 ± 0.029	0.105MetCys: 0.105 ± 0.007	0.798MetAsp: 0.798 ± 0.021	0.598MetGlu: 0.598 ± 0.016	0.425MetPhe: 0.425 ± 0.015	1.148MetGly: 1.148 ± 0.024	0.315MetHis: 0.315 ± 0.014	0.573MetIle: 0.573 ± 0.016	0.32MetLys: 0.32 ± 0.012	1.633MetLeu: 1.633 ± 0.03	0.282MetMet: 0.282 ± 0.011	0.379MetAsn: 0.379 ± 0.014	1.033MetPro: 1.033 ± 0.025	0.422MetGln: 0.422 ± 0.014	1.218MetArg: 1.218 ± 0.023	1.09MetSer: 1.09 ± 0.024	1.405MetThr: 1.405 ± 0.026	1.192MetVal: 1.192 ± 0.024	0.164MetTrp: 0.164 ± 0.009	0.257MetTyr: 0.257 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.156AsnAla: 2.156 ± 0.038	0.182AsnCys: 0.182 ± 0.01	0.87AsnAsp: 0.87 ± 0.021	0.75AsnGlu: 0.75 ± 0.017	0.432AsnPhe: 0.432 ± 0.015	1.988AsnGly: 1.988 ± 0.043	0.367AsnHis: 0.367 ± 0.012	0.517AsnIle: 0.517 ± 0.016	0.323AsnLys: 0.323 ± 0.013	1.702AsnLeu: 1.702 ± 0.028	0.267AsnMet: 0.267 ± 0.013	0.424AsnAsn: 0.424 ± 0.018	1.361AsnPro: 1.361 ± 0.03	0.526AsnGln: 0.526 ± 0.015	1.254AsnArg: 1.254 ± 0.023	1.009AsnSer: 1.009 ± 0.026	1.046AsnThr: 1.046 ± 0.031	1.221AsnVal: 1.221 ± 0.026	0.3AsnTrp: 0.3 ± 0.013	0.385AsnTyr: 0.385 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	11.243ProAla: 11.243 ± 0.092	0.451ProCys: 0.451 ± 0.017	4.659ProAsp: 4.659 ± 0.051	4.286ProGlu: 4.286 ± 0.053	1.498ProPhe: 1.498 ± 0.028	7.809ProGly: 7.809 ± 0.066	1.529ProHis: 1.529 ± 0.031	1.335ProIle: 1.335 ± 0.025	1.0ProLys: 1.0 ± 0.023	5.587ProLeu: 5.587 ± 0.059	0.964ProMet: 0.964 ± 0.023	1.006ProAsn: 1.006 ± 0.024	4.529ProPro: 4.529 ± 0.068	1.927ProGln: 1.927 ± 0.034	4.795ProArg: 4.795 ± 0.074	3.526ProSer: 3.526 ± 0.048	3.517ProThr: 3.517 ± 0.052	5.758ProVal: 5.758 ± 0.07	0.951ProTrp: 0.951 ± 0.018	1.274ProTyr: 1.274 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	3.914GlnAla: 3.914 ± 0.055	0.192GlnCys: 0.192 ± 0.009	1.423GlnAsp: 1.423 ± 0.027	1.313GlnGlu: 1.313 ± 0.027	0.697GlnPhe: 0.697 ± 0.018	2.317GlnGly: 2.317 ± 0.04	0.788GlnHis: 0.788 ± 0.021	0.957GlnIle: 0.957 ± 0.023	0.495GlnLys: 0.495 ± 0.017	3.566GlnLeu: 3.566 ± 0.039	0.407GlnMet: 0.407 ± 0.014	0.504GlnAsn: 0.504 ± 0.018	2.043GlnPro: 2.043 ± 0.04	1.62GlnGln: 1.62 ± 0.042	2.565GlnArg: 2.565 ± 0.038	1.26GlnSer: 1.26 ± 0.023	1.208GlnThr: 1.208 ± 0.027	2.556GlnVal: 2.556 ± 0.034	0.476GlnTrp: 0.476 ± 0.014	0.628GlnTyr: 0.628 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	11.127ArgAla: 11.127 ± 0.1	0.798ArgCys: 0.798 ± 0.02	3.88ArgAsp: 3.88 ± 0.04	4.53ArgGlu: 4.53 ± 0.055	2.147ArgPhe: 2.147 ± 0.03	6.29ArgGly: 6.29 ± 0.07	2.536ArgHis: 2.536 ± 0.043	3.135ArgIle: 3.135 ± 0.038	1.358ArgLys: 1.358 ± 0.026	9.397ArgLeu: 9.397 ± 0.075	1.67ArgMet: 1.67 ± 0.032	1.291ArgAsn: 1.291 ± 0.025	7.152ArgPro: 7.152 ± 0.104	2.643ArgGln: 2.643 ± 0.041	9.92ArgArg: 9.92 ± 0.153	4.308ArgSer: 4.308 ± 0.051	5.752ArgThr: 5.752 ± 0.057	5.495ArgVal: 5.495 ± 0.056	1.478ArgTrp: 1.478 ± 0.028	1.713ArgTyr: 1.713 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	6.956SerAla: 6.956 ± 0.069	0.477SerCys: 0.477 ± 0.014	2.215SerAsp: 2.215 ± 0.036	2.007SerGlu: 2.007 ± 0.034	1.401SerPhe: 1.401 ± 0.022	5.722SerGly: 5.722 ± 0.064	0.949SerHis: 0.949 ± 0.02	1.287SerIle: 1.287 ± 0.027	0.832SerLys: 0.832 ± 0.02	4.259SerLeu: 4.259 ± 0.047	0.955SerMet: 0.955 ± 0.02	0.881SerAsn: 0.881 ± 0.023	3.473SerPro: 3.473 ± 0.05	1.105SerGln: 1.105 ± 0.023	3.658SerArg: 3.658 ± 0.046	2.893SerSer: 2.893 ± 0.042	3.238SerThr: 3.238 ± 0.041	3.706SerVal: 3.706 ± 0.041	0.983SerTrp: 0.983 ± 0.021	1.107SerTyr: 1.107 ± 0.027	0.0SerXaa: 0.0 ± 0.0
Thr	9.778ThrAla: 9.778 ± 0.074	0.482ThrCys: 0.482 ± 0.017	3.43ThrAsp: 3.43 ± 0.047	2.85ThrGlu: 2.85 ± 0.036	1.425ThrPhe: 1.425 ± 0.029	6.905ThrGly: 6.905 ± 0.07	1.064ThrHis: 1.064 ± 0.021	1.366ThrIle: 1.366 ± 0.027	0.931ThrLys: 0.931 ± 0.023	5.565ThrLeu: 5.565 ± 0.052	0.861ThrMet: 0.861 ± 0.021	0.949ThrAsn: 0.949 ± 0.027	4.201ThrPro: 4.201 ± 0.053	1.121ThrGln: 1.121 ± 0.026	3.821ThrArg: 3.821 ± 0.042	2.747ThrSer: 2.747 ± 0.041	3.716ThrThr: 3.716 ± 0.073	6.23ThrVal: 6.23 ± 0.064	0.87ThrTrp: 0.87 ± 0.02	1.089ThrTyr: 1.089 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	10.525ValAla: 10.525 ± 0.072	0.637ValCys: 0.637 ± 0.018	4.701ValAsp: 4.701 ± 0.047	4.474ValGlu: 4.474 ± 0.055	2.181ValPhe: 2.181 ± 0.034	6.401ValGly: 6.401 ± 0.063	2.032ValHis: 2.032 ± 0.028	2.341ValIle: 2.341 ± 0.036	1.458ValLys: 1.458 ± 0.027	9.894ValLeu: 9.894 ± 0.074	1.186ValMet: 1.186 ± 0.022	1.563ValAsn: 1.563 ± 0.033	5.216ValPro: 5.216 ± 0.052	2.203ValGln: 2.203 ± 0.031	7.174ValArg: 7.174 ± 0.072	3.731ValSer: 3.731 ± 0.044	4.977ValThr: 4.977 ± 0.061	7.301ValVal: 7.301 ± 0.075	0.994ValTrp: 0.994 ± 0.022	1.402ValTyr: 1.402 ± 0.027	0.0ValXaa: 0.0 ± 0.0
Trp	1.749TrpAla: 1.749 ± 0.028	0.182TrpCys: 0.182 ± 0.009	0.781TrpAsp: 0.781 ± 0.02	0.7TrpGlu: 0.7 ± 0.019	0.46TrpPhe: 0.46 ± 0.014	1.014TrpGly: 1.014 ± 0.023	0.397TrpHis: 0.397 ± 0.015	0.491TrpIle: 0.491 ± 0.016	0.311TrpLys: 0.311 ± 0.011	1.743TrpLeu: 1.743 ± 0.031	0.282TrpMet: 0.282 ± 0.011	0.398TrpAsn: 0.398 ± 0.014	0.952TrpPro: 0.952 ± 0.02	0.67TrpGln: 0.67 ± 0.018	1.348TrpArg: 1.348 ± 0.025	0.975TrpSer: 0.975 ± 0.022	1.16TrpThr: 1.16 ± 0.024	0.924TrpVal: 0.924 ± 0.02	0.385TrpTrp: 0.385 ± 0.012	0.349TrpTyr: 0.349 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.403TyrAla: 2.403 ± 0.034	0.185TyrCys: 0.185 ± 0.01	1.245TyrAsp: 1.245 ± 0.032	0.884TyrGlu: 0.884 ± 0.02	0.58TyrPhe: 0.58 ± 0.016	2.076TyrGly: 2.076 ± 0.035	0.371TyrHis: 0.371 ± 0.013	0.378TyrIle: 0.378 ± 0.016	0.304TyrLys: 0.304 ± 0.012	2.244TyrLeu: 2.244 ± 0.032	0.197TyrMet: 0.197 ± 0.011	0.39TyrAsn: 0.39 ± 0.016	1.07TyrPro: 1.07 ± 0.024	0.635TyrGln: 0.635 ± 0.019	1.916TyrArg: 1.916 ± 0.034	0.886TyrSer: 0.886 ± 0.022	1.097TyrThr: 1.097 ± 0.031	1.33TyrVal: 1.33 ± 0.026	0.355TyrTrp: 0.355 ± 0.014	0.43TyrTyr: 0.43 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 7804 proteins (2315440 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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