Amino acid dipepetide frequency for Rubrivivax albus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	22.566AlaAla: 22.566 ± 0.232	1.398AlaCys: 1.398 ± 0.03	8.079AlaAsp: 8.079 ± 0.082	7.581AlaGlu: 7.581 ± 0.081	4.279AlaPhe: 4.279 ± 0.057	12.645AlaGly: 12.645 ± 0.124	2.944AlaHis: 2.944 ± 0.048	4.583AlaIle: 4.583 ± 0.061	3.003AlaLys: 3.003 ± 0.058	17.576AlaLeu: 17.576 ± 0.168	3.714AlaMet: 3.714 ± 0.055	2.343AlaAsn: 2.343 ± 0.041	7.308AlaPro: 7.308 ± 0.094	5.714AlaGln: 5.714 ± 0.07	10.931AlaArg: 10.931 ± 0.11	6.446AlaSer: 6.446 ± 0.091	6.906AlaThr: 6.906 ± 0.075	10.583AlaVal: 10.583 ± 0.088	2.649AlaTrp: 2.649 ± 0.05	2.377AlaTyr: 2.377 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	1.129CysAla: 1.129 ± 0.029	0.112CysCys: 0.112 ± 0.01	0.554CysAsp: 0.554 ± 0.02	0.437CysGlu: 0.437 ± 0.017	0.288CysPhe: 0.288 ± 0.013	1.025CysGly: 1.025 ± 0.027	0.305CysHis: 0.305 ± 0.031	0.339CysIle: 0.339 ± 0.015	0.168CysLys: 0.168 ± 0.011	0.786CysLeu: 0.786 ± 0.022	0.193CysMet: 0.193 ± 0.01	0.206CysAsn: 0.206 ± 0.013	0.542CysPro: 0.542 ± 0.021	0.224CysGln: 0.224 ± 0.012	0.7CysArg: 0.7 ± 0.023	0.483CysSer: 0.483 ± 0.019	0.502CysThr: 0.502 ± 0.021	0.671CysVal: 0.671 ± 0.024	0.12CysTrp: 0.12 ± 0.009	0.174CysTyr: 0.174 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	8.778AspAla: 8.778 ± 0.098	0.441AspCys: 0.441 ± 0.017	3.502AspAsp: 3.502 ± 0.058	3.279AspGlu: 3.279 ± 0.047	1.913AspPhe: 1.913 ± 0.039	5.715AspGly: 5.715 ± 0.071	1.268AspHis: 1.268 ± 0.032	2.05AspIle: 2.05 ± 0.043	1.265AspLys: 1.265 ± 0.036	5.951AspLeu: 5.951 ± 0.058	0.993AspMet: 0.993 ± 0.026	0.98AspAsn: 0.98 ± 0.027	3.61AspPro: 3.61 ± 0.047	1.532AspGln: 1.532 ± 0.032	4.068AspArg: 4.068 ± 0.055	1.973AspSer: 1.973 ± 0.034	2.792AspThr: 2.792 ± 0.045	4.161AspVal: 4.161 ± 0.061	1.065AspTrp: 1.065 ± 0.024	1.155AspTyr: 1.155 ± 0.031	0.0AspXaa: 0.0 ± 0.0
Glu	7.333GluAla: 7.333 ± 0.091	0.339GluCys: 0.339 ± 0.014	2.142GluAsp: 2.142 ± 0.041	1.851GluGlu: 1.851 ± 0.044	1.435GluPhe: 1.435 ± 0.035	3.681GluGly: 3.681 ± 0.056	1.338GluHis: 1.338 ± 0.032	2.22GluIle: 2.22 ± 0.043	1.236GluLys: 1.236 ± 0.038	5.325GluLeu: 5.325 ± 0.059	1.065GluMet: 1.065 ± 0.028	0.932GluAsn: 0.932 ± 0.026	2.801GluPro: 2.801 ± 0.044	2.282GluGln: 2.282 ± 0.044	5.107GluArg: 5.107 ± 0.067	2.028GluSer: 2.028 ± 0.032	2.445GluThr: 2.445 ± 0.038	3.951GluVal: 3.951 ± 0.052	0.639GluTrp: 0.639 ± 0.019	0.816GluTyr: 0.816 ± 0.024	0.0GluXaa: 0.0 ± 0.0
Phe	4.137PheAla: 4.137 ± 0.047	0.308PheCys: 0.308 ± 0.014	2.582PheAsp: 2.582 ± 0.039	1.923PheGlu: 1.923 ± 0.033	1.158PhePhe: 1.158 ± 0.03	3.384PheGly: 3.384 ± 0.048	0.697PheHis: 0.697 ± 0.021	1.155PheIle: 1.155 ± 0.03	0.848PheLys: 0.848 ± 0.025	2.626PheLeu: 2.626 ± 0.043	0.671PheMet: 0.671 ± 0.023	0.903PheAsn: 0.903 ± 0.028	1.433PhePro: 1.433 ± 0.026	0.94PheGln: 0.94 ± 0.023	1.926PheArg: 1.926 ± 0.034	1.675PheSer: 1.675 ± 0.037	1.81PheThr: 1.81 ± 0.031	2.788PheVal: 2.788 ± 0.044	0.487PheTrp: 0.487 ± 0.019	0.737PheTyr: 0.737 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	10.421GlyAla: 10.421 ± 0.11	0.972GlyCys: 0.972 ± 0.027	4.665GlyAsp: 4.665 ± 0.071	4.422GlyGlu: 4.422 ± 0.055	3.244GlyPhe: 3.244 ± 0.046	7.825GlyGly: 7.825 ± 0.156	2.189GlyHis: 2.189 ± 0.036	3.428GlyIle: 3.428 ± 0.052	2.362GlyLys: 2.362 ± 0.047	9.786GlyLeu: 9.786 ± 0.098	2.131GlyMet: 2.131 ± 0.036	1.886GlyAsn: 1.886 ± 0.046	3.839GlyPro: 3.839 ± 0.053	3.467GlyGln: 3.467 ± 0.049	6.948GlyArg: 6.948 ± 0.072	4.542GlySer: 4.542 ± 0.081	4.795GlyThr: 4.795 ± 0.079	6.897GlyVal: 6.897 ± 0.064	1.738GlyTrp: 1.738 ± 0.039	1.995GlyTyr: 1.995 ± 0.037	0.0GlyXaa: 0.0 ± 0.0
His	3.322HisAla: 3.322 ± 0.055	0.295HisCys: 0.295 ± 0.015	1.415HisAsp: 1.415 ± 0.033	1.135HisGlu: 1.135 ± 0.027	0.851HisPhe: 0.851 ± 0.024	2.469HisGly: 2.469 ± 0.045	0.67HisHis: 0.67 ± 0.022	0.699HisIle: 0.699 ± 0.023	0.455HisLys: 0.455 ± 0.016	2.461HisLeu: 2.461 ± 0.045	0.403HisMet: 0.403 ± 0.015	0.405HisAsn: 0.405 ± 0.018	1.623HisPro: 1.623 ± 0.033	0.699HisGln: 0.699 ± 0.02	1.956HisArg: 1.956 ± 0.038	0.803HisSer: 0.803 ± 0.022	1.027HisThr: 1.027 ± 0.023	1.808HisVal: 1.808 ± 0.04	0.489HisTrp: 0.489 ± 0.02	0.569HisTyr: 0.569 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	5.341IleAla: 5.341 ± 0.065	0.31IleCys: 0.31 ± 0.013	2.827IleAsp: 2.827 ± 0.041	2.454IleGlu: 2.454 ± 0.044	0.961IlePhe: 0.961 ± 0.029	3.824IleGly: 3.824 ± 0.051	0.695IleHis: 0.695 ± 0.021	0.962IleIle: 0.962 ± 0.032	0.943IleLys: 0.943 ± 0.027	2.565IleLeu: 2.565 ± 0.048	0.537IleMet: 0.537 ± 0.019	0.891IleAsn: 0.891 ± 0.027	1.687IlePro: 1.687 ± 0.035	0.991IleGln: 0.991 ± 0.028	2.268IleArg: 2.268 ± 0.043	1.582IleSer: 1.582 ± 0.033	2.012IleThr: 2.012 ± 0.043	3.374IleVal: 3.374 ± 0.059	0.398IleTrp: 0.398 ± 0.017	0.68IleTyr: 0.68 ± 0.024	0.0IleXaa: 0.0 ± 0.0
Lys	3.456LysAla: 3.456 ± 0.059	0.136LysCys: 0.136 ± 0.009	1.232LysAsp: 1.232 ± 0.03	0.908LysGlu: 0.908 ± 0.036	0.641LysPhe: 0.641 ± 0.021	1.857LysGly: 1.857 ± 0.04	0.512LysHis: 0.512 ± 0.02	0.943LysIle: 0.943 ± 0.031	0.877LysLys: 0.877 ± 0.033	2.659LysLeu: 2.659 ± 0.044	0.52LysMet: 0.52 ± 0.02	0.596LysAsn: 0.596 ± 0.021	1.588LysPro: 1.588 ± 0.036	0.798LysGln: 0.798 ± 0.024	1.779LysArg: 1.779 ± 0.039	1.23LysSer: 1.23 ± 0.033	1.415LysThr: 1.415 ± 0.036	1.969LysVal: 1.969 ± 0.045	0.254LysTrp: 0.254 ± 0.012	0.467LysTyr: 0.467 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	17.409LeuAla: 17.409 ± 0.153	0.899LeuCys: 0.899 ± 0.025	6.474LeuAsp: 6.474 ± 0.066	4.738LeuGlu: 4.738 ± 0.064	3.219LeuPhe: 3.219 ± 0.045	9.025LeuGly: 9.025 ± 0.095	2.554LeuHis: 2.554 ± 0.042	3.497LeuIle: 3.497 ± 0.058	3.013LeuLys: 3.013 ± 0.048	11.731LeuLeu: 11.731 ± 0.104	2.445LeuMet: 2.445 ± 0.037	2.266LeuAsn: 2.266 ± 0.037	6.896LeuPro: 6.896 ± 0.081	4.865LeuGln: 4.865 ± 0.059	8.805LeuArg: 8.805 ± 0.102	5.455LeuSer: 5.455 ± 0.064	5.331LeuThr: 5.331 ± 0.058	8.258LeuVal: 8.258 ± 0.089	1.602LeuTrp: 1.602 ± 0.038	1.845LeuTyr: 1.845 ± 0.035	0.0LeuXaa: 0.0 ± 0.0
Met	3.219MetAla: 3.219 ± 0.044	0.155MetCys: 0.155 ± 0.011	1.124MetAsp: 1.124 ± 0.027	0.803MetGlu: 0.803 ± 0.025	0.597MetPhe: 0.597 ± 0.02	1.679MetGly: 1.679 ± 0.034	0.553MetHis: 0.553 ± 0.019	0.765MetIle: 0.765 ± 0.025	0.798MetLys: 0.798 ± 0.025	2.48MetLeu: 2.48 ± 0.042	0.481MetMet: 0.481 ± 0.018	0.707MetAsn: 0.707 ± 0.021	1.566MetPro: 1.566 ± 0.033	0.951MetGln: 0.951 ± 0.024	1.753MetArg: 1.753 ± 0.035	1.372MetSer: 1.372 ± 0.029	1.494MetThr: 1.494 ± 0.033	1.645MetVal: 1.645 ± 0.032	0.212MetTrp: 0.212 ± 0.012	0.315MetTyr: 0.315 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	2.805AsnAla: 2.805 ± 0.046	0.216AsnCys: 0.216 ± 0.016	1.085AsnAsp: 1.085 ± 0.026	0.843AsnGlu: 0.843 ± 0.028	0.706AsnPhe: 0.706 ± 0.023	1.83AsnGly: 1.83 ± 0.051	0.482AsnHis: 0.482 ± 0.017	0.784AsnIle: 0.784 ± 0.026	0.496AsnLys: 0.496 ± 0.018	2.251AsnLeu: 2.251 ± 0.04	0.414AsnMet: 0.414 ± 0.016	0.484AsnAsn: 0.484 ± 0.02	1.59AsnPro: 1.59 ± 0.037	0.639AsnGln: 0.639 ± 0.022	1.454AsnArg: 1.454 ± 0.033	0.76AsnSer: 0.76 ± 0.027	1.079AsnThr: 1.079 ± 0.03	1.606AsnVal: 1.606 ± 0.035	0.329AsnTrp: 0.329 ± 0.014	0.474AsnTyr: 0.474 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	9.111ProAla: 9.111 ± 0.113	0.399ProCys: 0.399 ± 0.016	3.605ProAsp: 3.605 ± 0.054	3.289ProGlu: 3.289 ± 0.049	1.774ProPhe: 1.774 ± 0.034	5.599ProGly: 5.599 ± 0.065	1.15ProHis: 1.15 ± 0.029	1.555ProIle: 1.555 ± 0.032	1.3ProLys: 1.3 ± 0.029	5.876ProLeu: 5.876 ± 0.064	1.41ProMet: 1.41 ± 0.032	1.061ProAsn: 1.061 ± 0.028	3.621ProPro: 3.621 ± 0.075	2.004ProGln: 2.004 ± 0.036	3.671ProArg: 3.671 ± 0.05	2.543ProSer: 2.543 ± 0.045	2.758ProThr: 2.758 ± 0.038	4.728ProVal: 4.728 ± 0.053	1.036ProTrp: 1.036 ± 0.027	1.048ProTyr: 1.048 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	6.543GlnAla: 6.543 ± 0.089	0.271GlnCys: 0.271 ± 0.013	1.501GlnAsp: 1.501 ± 0.032	1.279GlnGlu: 1.279 ± 0.034	1.012GlnPhe: 1.012 ± 0.025	3.104GlnGly: 3.104 ± 0.046	0.921GlnHis: 0.921 ± 0.023	1.407GlnIle: 1.407 ± 0.033	0.725GlnLys: 0.725 ± 0.022	3.852GlnLeu: 3.852 ± 0.053	0.848GlnMet: 0.848 ± 0.023	0.583GlnAsn: 0.583 ± 0.017	2.399GlnPro: 2.399 ± 0.037	1.792GlnGln: 1.792 ± 0.036	4.086GlnArg: 4.086 ± 0.066	1.463GlnSer: 1.463 ± 0.032	1.771GlnThr: 1.771 ± 0.035	3.146GlnVal: 3.146 ± 0.045	0.653GlnTrp: 0.653 ± 0.022	0.578GlnTyr: 0.578 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	9.585ArgAla: 9.585 ± 0.099	0.733ArgCys: 0.733 ± 0.026	4.206ArgAsp: 4.206 ± 0.059	4.258ArgGlu: 4.258 ± 0.059	2.954ArgPhe: 2.954 ± 0.046	5.476ArgGly: 5.476 ± 0.066	2.424ArgHis: 2.424 ± 0.043	3.223ArgIle: 3.223 ± 0.047	1.59ArgLys: 1.59 ± 0.034	9.572ArgLeu: 9.572 ± 0.098	1.975ArgMet: 1.975 ± 0.029	1.475ArgAsn: 1.475 ± 0.035	4.088ArgPro: 4.088 ± 0.057	3.281ArgGln: 3.281 ± 0.052	7.027ArgArg: 7.027 ± 0.089	3.533ArgSer: 3.533 ± 0.051	3.65ArgThr: 3.65 ± 0.052	5.896ArgVal: 5.896 ± 0.069	1.717ArgTrp: 1.717 ± 0.039	1.725ArgTyr: 1.725 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	6.297SerAla: 6.297 ± 0.08	0.431SerCys: 0.431 ± 0.028	2.265SerAsp: 2.265 ± 0.043	2.029SerGlu: 2.029 ± 0.038	1.739SerPhe: 1.739 ± 0.032	4.748SerGly: 4.748 ± 0.093	1.005SerHis: 1.005 ± 0.024	1.722SerIle: 1.722 ± 0.036	1.001SerLys: 1.001 ± 0.027	4.862SerLeu: 4.862 ± 0.058	1.139SerMet: 1.139 ± 0.028	1.008SerAsn: 1.008 ± 0.027	2.736SerPro: 2.736 ± 0.043	1.381SerGln: 1.381 ± 0.03	3.286SerArg: 3.286 ± 0.049	2.405SerSer: 2.405 ± 0.047	2.685SerThr: 2.685 ± 0.055	3.603SerVal: 3.603 ± 0.049	0.716SerTrp: 0.716 ± 0.023	0.956SerTyr: 0.956 ± 0.025	0.0SerXaa: 0.0 ± 0.0
Thr	6.776ThrAla: 6.776 ± 0.087	0.423ThrCys: 0.423 ± 0.018	2.559ThrAsp: 2.559 ± 0.037	2.254ThrGlu: 2.254 ± 0.041	1.456ThrPhe: 1.456 ± 0.03	4.814ThrGly: 4.814 ± 0.087	1.13ThrHis: 1.13 ± 0.031	1.763ThrIle: 1.763 ± 0.035	0.927ThrLys: 0.927 ± 0.029	6.751ThrLeu: 6.751 ± 0.07	1.149ThrMet: 1.149 ± 0.028	0.964ThrAsn: 0.964 ± 0.028	3.724ThrPro: 3.724 ± 0.06	1.766ThrGln: 1.766 ± 0.032	3.634ThrArg: 3.634 ± 0.045	2.266ThrSer: 2.266 ± 0.046	2.797ThrThr: 2.797 ± 0.05	4.544ThrVal: 4.544 ± 0.056	0.819ThrTrp: 0.819 ± 0.025	0.94ThrTyr: 0.94 ± 0.029	0.0ThrXaa: 0.0 ± 0.0
Val	11.033ValAla: 11.033 ± 0.095	0.718ValCys: 0.718 ± 0.021	4.836ValAsp: 4.836 ± 0.059	3.999ValGlu: 3.999 ± 0.053	2.652ValPhe: 2.652 ± 0.04	5.935ValGly: 5.935 ± 0.079	1.844ValHis: 1.844 ± 0.036	2.999ValIle: 2.999 ± 0.054	2.032ValLys: 2.032 ± 0.041	8.888ValLeu: 8.888 ± 0.074	1.812ValMet: 1.812 ± 0.036	1.82ValAsn: 1.82 ± 0.038	4.529ValPro: 4.529 ± 0.057	3.091ValGln: 3.091 ± 0.042	5.584ValArg: 5.584 ± 0.068	3.76ValSer: 3.76 ± 0.057	4.172ValThr: 4.172 ± 0.072	6.707ValVal: 6.707 ± 0.08	1.165ValTrp: 1.165 ± 0.026	1.441ValTyr: 1.441 ± 0.031	0.0ValXaa: 0.0 ± 0.0
Trp	1.85TrpAla: 1.85 ± 0.039	0.201TrpCys: 0.201 ± 0.012	0.699TrpAsp: 0.699 ± 0.022	0.526TrpGlu: 0.526 ± 0.017	0.574TrpPhe: 0.574 ± 0.019	1.079TrpGly: 1.079 ± 0.025	0.474TrpHis: 0.474 ± 0.02	0.628TrpIle: 0.628 ± 0.02	0.358TrpLys: 0.358 ± 0.015	2.358TrpLeu: 2.358 ± 0.047	0.42TrpMet: 0.42 ± 0.017	0.374TrpAsn: 0.374 ± 0.013	1.023TrpPro: 1.023 ± 0.028	0.924TrpGln: 0.924 ± 0.027	1.77TrpArg: 1.77 ± 0.039	0.792TrpSer: 0.792 ± 0.026	0.896TrpThr: 0.896 ± 0.026	1.192TrpVal: 1.192 ± 0.033	0.408TrpTrp: 0.408 ± 0.017	0.283TrpTyr: 0.283 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.516TyrAla: 2.516 ± 0.039	0.201TyrCys: 0.201 ± 0.011	1.139TyrAsp: 1.139 ± 0.031	0.959TyrGlu: 0.959 ± 0.024	0.733TyrPhe: 0.733 ± 0.019	1.838TyrGly: 1.838 ± 0.039	0.398TyrHis: 0.398 ± 0.015	0.58TyrIle: 0.58 ± 0.018	0.44TyrLys: 0.44 ± 0.019	1.973TyrLeu: 1.973 ± 0.039	0.35TyrMet: 0.35 ± 0.014	0.442TyrAsn: 0.442 ± 0.018	0.934TyrPro: 0.934 ± 0.024	0.593TyrGln: 0.593 ± 0.021	1.634TyrArg: 1.634 ± 0.03	0.904TyrSer: 0.904 ± 0.026	1.118TyrThr: 1.118 ± 0.028	1.491TyrVal: 1.491 ± 0.032	0.334TyrTrp: 0.334 ± 0.015	0.453TyrTyr: 0.453 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4847 proteins (1628097 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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