Bat coronavirus Rp/Shaanxi2011

Taxonomy: Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae; Betacoronavirus; Sarbecovirus; Severe acute respiratory syndrome-related coronavirus

Average proteome isoelectric point is 6.9

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|R9QTA1|R9QTA1_SARS Growth factor-like peptide OS=Bat coronavirus Rp/Shaanxi2011 OX=1283332 PE=3 SV=1
MM1 pKa = 7.62ILLLLFLSSAKK12 pKa = 10.29AQEE15 pKa = 4.41GCGVISNKK23 pKa = 7.66PQRR26 pKa = 11.84TFDD29 pKa = 3.5QYY31 pKa = 11.06SSTFRR36 pKa = 11.84GVYY39 pKa = 10.32YY40 pKa = 10.6NDD42 pKa = 4.8DD43 pKa = 3.51IFRR46 pKa = 11.84SDD48 pKa = 3.84VLHH51 pKa = 6.33LTQDD55 pKa = 3.19YY56 pKa = 9.62FLPFNTNVTRR66 pKa = 11.84YY67 pKa = 9.8LSLNAAQNTIVYY79 pKa = 9.09FDD81 pKa = 3.35NHH83 pKa = 7.09VIPFYY88 pKa = 11.04DD89 pKa = 4.89GIYY92 pKa = 9.94FAATEE97 pKa = 4.09RR98 pKa = 11.84SNVIRR103 pKa = 11.84GWIFGSTFDD112 pKa = 4.94NRR114 pKa = 11.84SQSAIIVNNSTHH126 pKa = 6.74ILVKK130 pKa = 9.62VCNFVLCTEE139 pKa = 4.09PMFTVSRR146 pKa = 11.84NQHH149 pKa = 4.75YY150 pKa = 10.34KK151 pKa = 9.14SWVYY155 pKa = 8.83QHH157 pKa = 6.61ARR159 pKa = 11.84NCTYY163 pKa = 11.12DD164 pKa = 3.08VAYY167 pKa = 9.54PSFQLDD173 pKa = 3.13VSLKK177 pKa = 9.87NNVNFQHH184 pKa = 6.09LRR186 pKa = 11.84EE187 pKa = 4.53FIFKK191 pKa = 10.7NVDD194 pKa = 3.09GFLKK198 pKa = 10.13IYY200 pKa = 10.57SSYY203 pKa = 11.11EE204 pKa = 3.83PINVVSGIPSGFSVLKK220 pKa = 10.25PVMSLPLGINITGMRR235 pKa = 11.84VVMTMFSNTQANFLTEE251 pKa = 3.54NAAYY255 pKa = 9.94YY256 pKa = 10.3VGYY259 pKa = 10.29LKK261 pKa = 10.59PRR263 pKa = 11.84TFMLQFNTNGTIVNAVDD280 pKa = 4.46CSQDD284 pKa = 3.36PLSEE288 pKa = 4.17LKK290 pKa = 9.77CTLKK294 pKa = 10.81NFNITKK300 pKa = 10.5GIYY303 pKa = 6.74QTSNFRR309 pKa = 11.84VSPTQEE315 pKa = 3.56VVRR318 pKa = 11.84FPNITNRR325 pKa = 11.84CPFDD329 pKa = 3.51KK330 pKa = 10.89VFNATRR336 pKa = 11.84FPSVYY341 pKa = 9.26AWEE344 pKa = 4.04RR345 pKa = 11.84TKK347 pKa = 10.81ISDD350 pKa = 3.69CVADD354 pKa = 3.7YY355 pKa = 9.98TVLYY359 pKa = 10.29NSTSFSTFKK368 pKa = 10.75CYY370 pKa = 10.03GVSPSKK376 pKa = 11.02LIDD379 pKa = 3.28LCFTSVYY386 pKa = 10.97ADD388 pKa = 3.29TFLIRR393 pKa = 11.84SSEE396 pKa = 4.01VRR398 pKa = 11.84QVAPGEE404 pKa = 4.2TGVIADD410 pKa = 4.42YY411 pKa = 10.82NYY413 pKa = 11.14KK414 pKa = 10.72LPDD417 pKa = 4.27DD418 pKa = 3.81FTGCVIAWNTANQDD432 pKa = 2.97QGQYY436 pKa = 10.33YY437 pKa = 9.01YY438 pKa = 10.87RR439 pKa = 11.84SSRR442 pKa = 11.84KK443 pKa = 9.15EE444 pKa = 3.38KK445 pKa = 10.57LKK447 pKa = 10.65PFEE450 pKa = 5.29RR451 pKa = 11.84DD452 pKa = 3.0LSSDD456 pKa = 3.41EE457 pKa = 4.25NGVYY461 pKa = 9.51TLSTYY466 pKa = 11.13DD467 pKa = 4.25FYY469 pKa = 11.18PSVPLDD475 pKa = 3.6YY476 pKa = 10.54QATRR480 pKa = 11.84VVVLSFEE487 pKa = 4.61LLNAPATVCGPKK499 pKa = 10.49LSTTLVKK506 pKa = 10.42NQCVNFNFNGLKK518 pKa = 9.12GTGVLTASSKK528 pKa = 10.59KK529 pKa = 10.02FQSFQQFGRR538 pKa = 11.84DD539 pKa = 3.18ASDD542 pKa = 3.34FTDD545 pKa = 3.68SVRR548 pKa = 11.84DD549 pKa = 3.77PQTLEE554 pKa = 3.83ILDD557 pKa = 4.16ISPCSFGGVSVITPGTNASTEE578 pKa = 4.27VAVLYY583 pKa = 10.7QDD585 pKa = 4.29VNCTDD590 pKa = 3.07VPTAINADD598 pKa = 3.45QLTPAWRR605 pKa = 11.84VYY607 pKa = 9.55STGINVFQTQAGCLIGAEE625 pKa = 4.44HH626 pKa = 6.46VNASYY631 pKa = 11.03EE632 pKa = 4.01CDD634 pKa = 3.21IPIGAGICASYY645 pKa = 8.41HH646 pKa = 4.65TASVLRR652 pKa = 11.84STGQKK657 pKa = 10.41SIVAYY662 pKa = 9.53TMSLGAEE669 pKa = 3.91NSIAYY674 pKa = 9.44ANNSIAIPTNFSISVTTEE692 pKa = 3.49VMPVSMAKK700 pKa = 9.66TSVDD704 pKa = 3.1CTMYY708 pKa = 10.29ICGDD712 pKa = 3.56SLEE715 pKa = 4.61CSNLLLQYY723 pKa = 11.24GSFCTQLNRR732 pKa = 11.84ALTGIAIEE740 pKa = 4.08QDD742 pKa = 3.23KK743 pKa = 8.9NTQEE747 pKa = 3.75VFAQVKK753 pKa = 9.11QMYY756 pKa = 7.06KK757 pKa = 9.37TPAIKK762 pKa = 10.61DD763 pKa = 3.33FGGFNFSQILPDD775 pKa = 3.66PSKK778 pKa = 8.47PTKK781 pKa = 10.11RR782 pKa = 11.84SFIEE786 pKa = 4.3DD787 pKa = 3.61LLFNKK792 pKa = 7.99VTLADD797 pKa = 3.57AGFMKK802 pKa = 10.37QYY804 pKa = 10.74GEE806 pKa = 4.27CLGDD810 pKa = 3.41ISARR814 pKa = 11.84DD815 pKa = 4.03LICAQKK821 pKa = 10.77FNGLTVLPPLLTDD834 pKa = 3.7EE835 pKa = 5.07MIAAYY840 pKa = 8.13TAALVSGTATAGWTFGAGAALQIPFAMQMAYY871 pKa = 10.08RR872 pKa = 11.84FNGIGVTQNVLYY884 pKa = 10.46EE885 pKa = 4.09NQKK888 pKa = 10.62QIANQFNKK896 pKa = 10.46AISQIQEE903 pKa = 4.19SLTTTSTALGKK914 pKa = 10.37LQDD917 pKa = 3.95VVNQNAQALNTLVKK931 pKa = 10.38QLSSNFGAISSVLNDD946 pKa = 3.17ILSRR950 pKa = 11.84LDD952 pKa = 3.31KK953 pKa = 11.45VEE955 pKa = 5.19AEE957 pKa = 4.28VQIDD961 pKa = 3.56RR962 pKa = 11.84LITGRR967 pKa = 11.84LQSLQTYY974 pKa = 7.4VTQQLIRR981 pKa = 11.84AAEE984 pKa = 3.85IRR986 pKa = 11.84ASANLAATKK995 pKa = 9.96MSEE998 pKa = 4.28CVLGQSKK1005 pKa = 10.12RR1006 pKa = 11.84VDD1008 pKa = 4.0FCGKK1012 pKa = 9.92GYY1014 pKa = 10.57HH1015 pKa = 6.84LMSFPQAAPHH1025 pKa = 5.76GVVFLHH1031 pKa = 5.25VTYY1034 pKa = 10.82VPSQEE1039 pKa = 4.9RR1040 pKa = 11.84NFTTAPAICHH1050 pKa = 5.73EE1051 pKa = 4.45GKK1053 pKa = 10.56AYY1055 pKa = 9.93FPRR1058 pKa = 11.84EE1059 pKa = 3.84GVFVSNGTSWFITQRR1074 pKa = 11.84NFYY1077 pKa = 9.51SPQIITTDD1085 pKa = 3.18NTFVAGSCNVVIGIINNTVYY1105 pKa = 10.97DD1106 pKa = 4.22PLQPEE1111 pKa = 4.19LDD1113 pKa = 3.85SFKK1116 pKa = 11.4EE1117 pKa = 3.91EE1118 pKa = 3.56LDD1120 pKa = 3.63KK1121 pKa = 11.53YY1122 pKa = 10.15FKK1124 pKa = 10.99NHH1126 pKa = 6.01TSPDD1130 pKa = 3.14VDD1132 pKa = 4.4LGDD1135 pKa = 3.31ISGINASVVNIQKK1148 pKa = 10.63EE1149 pKa = 3.92IDD1151 pKa = 3.67RR1152 pKa = 11.84LNEE1155 pKa = 3.5VAKK1158 pKa = 10.61NLNEE1162 pKa = 4.14SLIDD1166 pKa = 3.75LQEE1169 pKa = 4.17LGKK1172 pKa = 10.54YY1173 pKa = 6.98EE1174 pKa = 5.3QYY1176 pKa = 10.78IKK1178 pKa = 10.03WPWYY1182 pKa = 8.39VWLGFIAGLIAIVMVTILLCCMTSCCSCLKK1212 pKa = 10.16GACSCGSCCKK1222 pKa = 10.16FDD1224 pKa = 4.43EE1225 pKa = 5.39DD1226 pKa = 5.38DD1227 pKa = 4.38SEE1229 pKa = 4.36PVLKK1233 pKa = 10.36GVKK1236 pKa = 9.35LHH1238 pKa = 5.3YY1239 pKa = 9.44TT1240 pKa = 3.44

Molecular weight: 137.63 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|R9QTH1|R9QTH1_SARS ORF3 protein OS=Bat coronavirus Rp/Shaanxi2011 OX=1283332 PE=4 SV=1
MM1 pKa = 7.77SDD3 pKa = 4.56NGPQNQRR10 pKa = 11.84SAPRR14 pKa = 11.84ITFGGPSDD22 pKa = 3.8STDD25 pKa = 3.04NNQDD29 pKa = 3.07GGRR32 pKa = 11.84SGARR36 pKa = 11.84PKK38 pKa = 10.25QRR40 pKa = 11.84RR41 pKa = 11.84PQGLPNNTASWFTALTQHH59 pKa = 6.06GKK61 pKa = 10.36EE62 pKa = 3.96EE63 pKa = 4.07LRR65 pKa = 11.84FPRR68 pKa = 11.84GQGVPINTNSGKK80 pKa = 10.01DD81 pKa = 3.58DD82 pKa = 3.56QIGYY86 pKa = 8.17YY87 pKa = 9.92RR88 pKa = 11.84RR89 pKa = 11.84ATRR92 pKa = 11.84RR93 pKa = 11.84VRR95 pKa = 11.84GGDD98 pKa = 3.09GKK100 pKa = 10.39MKK102 pKa = 9.92EE103 pKa = 4.5LSPRR107 pKa = 11.84WYY109 pKa = 10.01FYY111 pKa = 11.5YY112 pKa = 10.73LGTGPEE118 pKa = 3.63ASLPYY123 pKa = 9.9GANKK127 pKa = 10.09EE128 pKa = 4.16GIIWVATEE136 pKa = 4.18GALNTPKK143 pKa = 10.91DD144 pKa = 4.0HH145 pKa = 7.46IGTRR149 pKa = 11.84NPNNNAAIVLQLPQGTTLPKK169 pKa = 10.34GFYY172 pKa = 10.67AEE174 pKa = 4.5GSRR177 pKa = 11.84GGSQASSRR185 pKa = 11.84SSSRR189 pKa = 11.84SRR191 pKa = 11.84GNSRR195 pKa = 11.84NSTPGSSRR203 pKa = 11.84GNSPARR209 pKa = 11.84MASGGGEE216 pKa = 3.84TALALLLLDD225 pKa = 4.89RR226 pKa = 11.84LNQLEE231 pKa = 4.58SKK233 pKa = 10.86VSGKK237 pKa = 10.04GQQQQGQTVTKK248 pKa = 9.98KK249 pKa = 10.44SAAEE253 pKa = 3.73ASKK256 pKa = 10.76KK257 pKa = 9.61PRR259 pKa = 11.84QKK261 pKa = 9.55RR262 pKa = 11.84TATKK266 pKa = 10.22SYY268 pKa = 11.04NVTQAFGRR276 pKa = 11.84RR277 pKa = 11.84GPEE280 pKa = 3.4QTQGNFGDD288 pKa = 3.74QDD290 pKa = 5.15LIRR293 pKa = 11.84QGTDD297 pKa = 2.96YY298 pKa = 11.27KK299 pKa = 10.5HH300 pKa = 6.32WPQIAQFAPSASAFFGMSRR319 pKa = 11.84IGMEE323 pKa = 4.16VTPSGTWLTYY333 pKa = 10.42HH334 pKa = 7.06GAIKK338 pKa = 10.61LDD340 pKa = 4.18DD341 pKa = 4.89KK342 pKa = 11.64DD343 pKa = 3.91PQFKK347 pKa = 11.14DD348 pKa = 3.7NVILLNKK355 pKa = 10.01HH356 pKa = 4.67IDD358 pKa = 3.35AYY360 pKa = 9.77KK361 pKa = 9.88TFPPTEE367 pKa = 3.95PKK369 pKa = 9.88KK370 pKa = 10.6DD371 pKa = 3.48KK372 pKa = 10.73KK373 pKa = 10.99KK374 pKa = 9.88KK375 pKa = 8.29TDD377 pKa = 3.29EE378 pKa = 4.34AQPLPQRR385 pKa = 11.84KK386 pKa = 8.41KK387 pKa = 10.06QPTVTLLPAADD398 pKa = 3.84MDD400 pKa = 4.26DD401 pKa = 5.3FSRR404 pKa = 11.84QLQNSMSGASADD416 pKa = 3.63STQAA420 pKa = 3.04

Molecular weight: 45.79 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

9233

76

4374

1319.0

147.18

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.181 ± 0.157

3.033 ± 0.403

5.22 ± 0.496

4.679 ± 0.638

4.787 ± 0.337

6.076 ± 0.487

2.015 ± 0.314

5.058 ± 0.614

5.675 ± 0.51

9.412 ± 0.65

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.329 ± 0.212

5.318 ± 0.382

4.04 ± 0.316

3.78 ± 0.515

3.737 ± 0.504

6.867 ± 0.447

7.062 ± 0.22

8.036 ± 0.635

1.137 ± 0.222

4.56 ± 0.294
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski