Amino acid dipepetide frequency for Trichoplusia ni TED virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.05AlaAla: 1.05 ± 0.504
0.525AlaCys: 0.525 ± 0.509
1.05AlaAsp: 1.05 ± 0.611
1.575AlaGlu: 1.575 ± 0.501
2.1AlaPhe: 2.1 ± 0.196
0.0AlaGly: 0.0 ± 0.0
0.525AlaHis: 0.525 ± 0.705
4.724AlaIle: 4.724 ± 1.845
2.625AlaLys: 2.625 ± 0.63
6.824AlaLeu: 6.824 ± 1.222
0.0AlaMet: 0.0 ± 0.0
1.575AlaAsn: 1.575 ± 0.446
1.05AlaPro: 1.05 ± 0.504
1.575AlaGln: 1.575 ± 0.501
1.575AlaArg: 1.575 ± 0.917
6.299AlaSer: 6.299 ± 1.364
4.199AlaThr: 4.199 ± 0.882
1.575AlaVal: 1.575 ± 0.903
0.525AlaTrp: 0.525 ± 0.306
1.575AlaTyr: 1.575 ± 0.564
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.575CysAsp: 1.575 ± 1.186
0.525CysGlu: 0.525 ± 0.509
0.0CysPhe: 0.0 ± 0.0
1.05CysGly: 1.05 ± 0.442
0.0CysHis: 0.0 ± 0.0
1.05CysIle: 1.05 ± 0.442
0.525CysLys: 0.525 ± 0.306
1.575CysLeu: 1.575 ± 0.446
0.525CysMet: 0.525 ± 0.777
0.525CysAsn: 0.525 ± 0.306
0.525CysPro: 0.525 ± 0.509
1.575CysGln: 1.575 ± 0.501
0.525CysArg: 0.525 ± 0.306
0.525CysSer: 0.525 ± 0.306
1.575CysThr: 1.575 ± 0.917
0.525CysVal: 0.525 ± 0.306
0.525CysTrp: 0.525 ± 0.509
2.1CysTyr: 2.1 ± 0.196
0.0CysXaa: 0.0 ± 0.0
Asp
2.625AspAla: 2.625 ± 0.805
0.525AspCys: 0.525 ± 0.509
3.675AspAsp: 3.675 ± 0.966
4.199AspGlu: 4.199 ± 0.637
3.675AspPhe: 3.675 ± 0.465
3.15AspGly: 3.15 ± 1.833
1.05AspHis: 1.05 ± 0.611
3.675AspIle: 3.675 ± 1.34
4.724AspLys: 4.724 ± 0.884
5.774AspLeu: 5.774 ± 1.062
0.0AspMet: 0.0 ± 0.0
2.625AspAsn: 2.625 ± 1.06
3.15AspPro: 3.15 ± 1.074
3.15AspGln: 3.15 ± 0.415
1.05AspArg: 1.05 ± 0.442
2.1AspSer: 2.1 ± 0.574
2.1AspThr: 2.1 ± 0.196
4.199AspVal: 4.199 ± 1.026
0.525AspTrp: 0.525 ± 0.705
2.625AspTyr: 2.625 ± 2.79
0.0AspXaa: 0.0 ± 0.0
Glu
3.675GluAla: 3.675 ± 2.023
2.1GluCys: 2.1 ± 0.792
2.1GluAsp: 2.1 ± 2.038
2.625GluGlu: 2.625 ± 0.11
4.199GluPhe: 4.199 ± 1.33
0.0GluGly: 0.0 ± 0.0
3.15GluHis: 3.15 ± 1.833
4.724GluIle: 4.724 ± 1.691
4.724GluLys: 4.724 ± 1.364
6.299GluLeu: 6.299 ± 0.588
1.05GluMet: 1.05 ± 0.442
3.675GluAsn: 3.675 ± 1.34
3.15GluPro: 3.15 ± 1.568
3.675GluGln: 3.675 ± 1.327
1.05GluArg: 1.05 ± 0.611
4.199GluSer: 4.199 ± 1.149
4.724GluThr: 4.724 ± 2.682
2.625GluVal: 2.625 ± 1.528
0.0GluTrp: 0.0 ± 0.0
3.675GluTyr: 3.675 ± 0.721
0.0GluXaa: 0.0 ± 0.0
Phe
2.1PheAla: 2.1 ± 0.884
1.05PheCys: 1.05 ± 0.611
1.05PheAsp: 1.05 ± 0.611
1.575PheGlu: 1.575 ± 0.917
0.525PhePhe: 0.525 ± 0.509
0.525PheGly: 0.525 ± 0.306
1.05PheHis: 1.05 ± 0.611
4.199PheIle: 4.199 ± 0.637
2.625PheLys: 2.625 ± 1.682
1.575PheLeu: 1.575 ± 0.917
0.525PheMet: 0.525 ± 0.509
4.199PheAsn: 4.199 ± 1.118
1.05PhePro: 1.05 ± 1.019
1.575PheGln: 1.575 ± 0.446
2.1PheArg: 2.1 ± 0.574
3.675PheSer: 3.675 ± 0.697
4.199PheThr: 4.199 ± 1.584
2.1PheVal: 2.1 ± 1.14
0.0PheTrp: 0.0 ± 0.0
2.625PheTyr: 2.625 ± 0.901
0.0PheXaa: 0.0 ± 0.0
Gly
1.05GlyAla: 1.05 ± 0.442
1.05GlyCys: 1.05 ± 0.807
0.525GlyAsp: 0.525 ± 0.306
1.05GlyGlu: 1.05 ± 0.611
0.525GlyPhe: 0.525 ± 0.306
0.0GlyGly: 0.0 ± 0.0
2.1GlyHis: 2.1 ± 0.574
4.199GlyIle: 4.199 ± 2.031
2.625GlyLys: 2.625 ± 1.06
2.625GlyLeu: 2.625 ± 0.805
0.525GlyMet: 0.525 ± 0.539
3.675GlyAsn: 3.675 ± 3.07
1.575GlyPro: 1.575 ± 0.446
2.625GlyGln: 2.625 ± 0.63
1.575GlyArg: 1.575 ± 0.564
3.15GlySer: 3.15 ± 1.003
1.575GlyThr: 1.575 ± 0.446
0.525GlyVal: 0.525 ± 0.705
0.0GlyTrp: 0.0 ± 0.0
1.575GlyTyr: 1.575 ± 0.917
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.525HisCys: 0.525 ± 0.306
1.575HisAsp: 1.575 ± 1.186
1.575HisGlu: 1.575 ± 1.186
1.575HisPhe: 1.575 ± 0.446
1.05HisGly: 1.05 ± 0.611
1.575HisHis: 1.575 ± 0.564
2.625HisIle: 2.625 ± 1.06
2.1HisLys: 2.1 ± 1.222
2.1HisLeu: 2.1 ± 1.222
0.525HisMet: 0.525 ± 0.306
1.05HisAsn: 1.05 ± 0.807
1.05HisPro: 1.05 ± 0.504
0.525HisGln: 0.525 ± 0.509
3.15HisArg: 3.15 ± 1.074
3.15HisSer: 3.15 ± 0.462
2.625HisThr: 2.625 ± 0.966
0.525HisVal: 0.525 ± 0.705
0.0HisTrp: 0.0 ± 0.0
1.05HisTyr: 1.05 ± 0.442
0.0HisXaa: 0.0 ± 0.0
Ile
1.05IleAla: 1.05 ± 0.442
1.575IleCys: 1.575 ± 0.446
6.299IleAsp: 6.299 ± 2.355
4.724IleGlu: 4.724 ± 0.782
1.05IlePhe: 1.05 ± 0.504
1.575IleGly: 1.575 ± 0.917
4.724IleHis: 4.724 ± 1.332
6.824IleIle: 6.824 ± 2.635
6.299IleLys: 6.299 ± 2.255
6.824IleLeu: 6.824 ± 0.874
0.525IleMet: 0.525 ± 0.705
5.774IleAsn: 5.774 ± 0.554
6.824IlePro: 6.824 ± 0.874
4.199IleGln: 4.199 ± 1.768
6.299IleArg: 6.299 ± 0.923
3.675IleSer: 3.675 ± 1.635
3.15IleThr: 3.15 ± 1.344
6.824IleVal: 6.824 ± 1.781
0.525IleTrp: 0.525 ± 0.306
1.05IleTyr: 1.05 ± 0.504
0.0IleXaa: 0.0 ± 0.0
Lys
2.1LysAla: 2.1 ± 1.008
2.1LysCys: 2.1 ± 0.792
2.625LysAsp: 2.625 ± 1.06
4.724LysGlu: 4.724 ± 0.9
3.675LysPhe: 3.675 ± 0.966
2.1LysGly: 2.1 ± 0.792
0.525LysHis: 0.525 ± 0.306
4.199LysIle: 4.199 ± 1.584
3.675LysLys: 3.675 ± 0.465
5.249LysLeu: 5.249 ± 1.317
1.575LysMet: 1.575 ± 0.446
2.1LysAsn: 2.1 ± 0.884
5.774LysPro: 5.774 ± 0.437
2.1LysGln: 2.1 ± 0.792
4.199LysArg: 4.199 ± 0.882
3.675LysSer: 3.675 ± 0.966
7.874LysThr: 7.874 ± 1.456
4.199LysVal: 4.199 ± 0.392
0.525LysTrp: 0.525 ± 0.306
4.199LysTyr: 4.199 ± 1.584
0.0LysXaa: 0.0 ± 0.0
Leu
5.249LeuAla: 5.249 ± 1.014
1.575LeuCys: 1.575 ± 0.501
3.675LeuAsp: 3.675 ± 1.635
9.449LeuGlu: 9.449 ± 3.076
3.15LeuPhe: 3.15 ± 0.415
5.249LeuGly: 5.249 ± 1.199
1.05LeuHis: 1.05 ± 0.807
5.249LeuIle: 5.249 ± 2.492
5.774LeuLys: 5.774 ± 1.198
5.774LeuLeu: 5.774 ± 1.198
1.05LeuMet: 1.05 ± 0.442
7.349LeuAsn: 7.349 ± 0.944
4.724LeuPro: 4.724 ± 2.735
6.824LeuGln: 6.824 ± 1.574
6.824LeuArg: 6.824 ± 1.136
5.774LeuSer: 5.774 ± 1.447
6.824LeuThr: 6.824 ± 1.675
4.199LeuVal: 4.199 ± 0.476
0.0LeuTrp: 0.0 ± 0.0
3.15LeuTyr: 3.15 ± 2.302
0.0LeuXaa: 0.0 ± 0.0
Met
0.525MetAla: 0.525 ± 0.509
0.0MetCys: 0.0 ± 0.0
2.1MetAsp: 2.1 ± 1.222
0.0MetGlu: 0.0 ± 0.0
0.525MetPhe: 0.525 ± 0.306
1.575MetGly: 1.575 ± 0.501
0.0MetHis: 0.0 ± 0.0
2.1MetIle: 2.1 ± 0.884
1.05MetLys: 1.05 ± 0.611
2.625MetLeu: 2.625 ± 1.308
1.05MetMet: 1.05 ± 0.442
1.05MetAsn: 1.05 ± 0.442
2.1MetPro: 2.1 ± 1.008
0.0MetGln: 0.0 ± 0.0
0.525MetArg: 0.525 ± 0.705
1.05MetSer: 1.05 ± 0.807
1.575MetThr: 1.575 ± 1.186
1.05MetVal: 1.05 ± 0.442
0.0MetTrp: 0.0 ± 0.0
0.525MetTyr: 0.525 ± 0.306
0.0MetXaa: 0.0 ± 0.0
Asn
3.675AsnAla: 3.675 ± 0.697
0.525AsnCys: 0.525 ± 0.306
2.1AsnAsp: 2.1 ± 0.196
5.774AsnGlu: 5.774 ± 1.546
2.625AsnPhe: 2.625 ± 0.63
3.15AsnGly: 3.15 ± 1.513
1.05AsnHis: 1.05 ± 0.611
4.199AsnIle: 4.199 ± 1.149
3.15AsnLys: 3.15 ± 1.003
5.249AsnLeu: 5.249 ± 1.159
1.05AsnMet: 1.05 ± 1.019
3.15AsnAsn: 3.15 ± 1.568
5.774AsnPro: 5.774 ± 1.767
3.15AsnGln: 3.15 ± 1.91
1.575AsnArg: 1.575 ± 0.446
3.15AsnSer: 3.15 ± 0.415
4.199AsnThr: 4.199 ± 0.882
4.199AsnVal: 4.199 ± 2.031
0.525AsnTrp: 0.525 ± 0.705
1.575AsnTyr: 1.575 ± 1.186
0.0AsnXaa: 0.0 ± 0.0
Pro
2.1ProAla: 2.1 ± 0.792
0.0ProCys: 0.0 ± 0.0
2.625ProAsp: 2.625 ± 0.11
3.15ProGlu: 3.15 ± 1.91
2.625ProPhe: 2.625 ± 0.901
2.1ProGly: 2.1 ± 2.101
1.05ProHis: 1.05 ± 0.504
8.399ProIle: 8.399 ± 2.94
4.199ProLys: 4.199 ± 0.476
5.249ProLeu: 5.249 ± 1.159
2.1ProMet: 2.1 ± 1.14
6.299ProAsn: 6.299 ± 3.135
6.299ProPro: 6.299 ± 6.58
4.199ProGln: 4.199 ± 2.017
2.1ProArg: 2.1 ± 0.574
3.675ProSer: 3.675 ± 0.463
2.625ProThr: 2.625 ± 1.308
3.675ProVal: 3.675 ± 2.181
0.0ProTrp: 0.0 ± 0.0
3.15ProTyr: 3.15 ± 1.003
0.0ProXaa: 0.0 ± 0.0
Gln
2.1GlnAla: 2.1 ± 0.574
1.05GlnCys: 1.05 ± 0.504
3.675GlnAsp: 3.675 ± 0.721
2.1GlnGlu: 2.1 ± 1.008
1.575GlnPhe: 1.575 ± 0.564
2.625GlnGly: 2.625 ± 0.867
2.1GlnHis: 2.1 ± 0.876
4.199GlnIle: 4.199 ± 1.474
3.15GlnLys: 3.15 ± 1.127
2.625GlnLeu: 2.625 ± 1.328
2.1GlnMet: 2.1 ± 0.574
2.1GlnAsn: 2.1 ± 1.222
3.15GlnPro: 3.15 ± 1.91
4.724GlnGln: 4.724 ± 0.962
3.675GlnArg: 3.675 ± 1.391
4.199GlnSer: 4.199 ± 2.412
2.1GlnThr: 2.1 ± 0.876
2.1GlnVal: 2.1 ± 1.222
0.525GlnTrp: 0.525 ± 0.306
2.625GlnTyr: 2.625 ± 0.901
0.0GlnXaa: 0.0 ± 0.0
Arg
2.1ArgAla: 2.1 ± 2.101
0.525ArgCys: 0.525 ± 0.705
4.199ArgAsp: 4.199 ± 0.637
2.625ArgGlu: 2.625 ± 0.11
2.1ArgPhe: 2.1 ± 0.574
3.15ArgGly: 3.15 ± 0.892
0.525ArgHis: 0.525 ± 0.306
3.675ArgIle: 3.675 ± 0.721
3.675ArgLys: 3.675 ± 0.966
7.349ArgLeu: 7.349 ± 0.929
2.1ArgMet: 2.1 ± 0.574
2.1ArgAsn: 2.1 ± 1.008
4.199ArgPro: 4.199 ± 1.149
4.199ArgGln: 4.199 ± 1.931
0.525ArgArg: 0.525 ± 0.306
1.575ArgSer: 1.575 ± 0.446
2.1ArgThr: 2.1 ± 1.222
3.15ArgVal: 3.15 ± 1.344
0.525ArgTrp: 0.525 ± 0.306
2.1ArgTyr: 2.1 ± 1.222
0.0ArgXaa: 0.0 ± 0.0
Ser
3.15SerAla: 3.15 ± 1.074
0.525SerCys: 0.525 ± 0.509
4.199SerAsp: 4.199 ± 1.149
5.774SerGlu: 5.774 ± 0.915
1.05SerPhe: 1.05 ± 0.442
2.1SerGly: 2.1 ± 1.008
1.05SerHis: 1.05 ± 0.504
3.15SerIle: 3.15 ± 1.326
3.15SerLys: 3.15 ± 1.344
6.824SerLeu: 6.824 ± 3.459
1.575SerMet: 1.575 ± 0.903
3.675SerAsn: 3.675 ± 0.982
3.675SerPro: 3.675 ± 0.463
3.15SerGln: 3.15 ± 1.003
6.299SerArg: 6.299 ± 2.147
8.399SerSer: 8.399 ± 1.414
5.774SerThr: 5.774 ± 0.893
1.575SerVal: 1.575 ± 0.446
0.0SerTrp: 0.0 ± 0.0
2.1SerTyr: 2.1 ± 0.876
0.0SerXaa: 0.0 ± 0.0
Thr
4.724ThrAla: 4.724 ± 0.086
1.575ThrCys: 1.575 ± 0.501
5.774ThrAsp: 5.774 ± 1.943
2.625ThrGlu: 2.625 ± 0.805
2.625ThrPhe: 2.625 ± 1.06
1.575ThrGly: 1.575 ± 1.427
1.575ThrHis: 1.575 ± 0.903
6.299ThrIle: 6.299 ± 1.51
7.874ThrLys: 7.874 ± 1.261
7.874ThrLeu: 7.874 ± 1.995
1.05ThrMet: 1.05 ± 0.54
3.675ThrAsn: 3.675 ± 0.721
3.15ThrPro: 3.15 ± 1.003
2.1ThrGln: 2.1 ± 0.574
3.675ThrArg: 3.675 ± 0.463
2.625ThrSer: 2.625 ± 1.528
3.675ThrThr: 3.675 ± 0.721
3.15ThrVal: 3.15 ± 1.074
0.525ThrTrp: 0.525 ± 0.705
2.1ThrTyr: 2.1 ± 1.587
0.0ThrXaa: 0.0 ± 0.0
Val
1.05ValAla: 1.05 ± 0.611
0.525ValCys: 0.525 ± 0.306
1.575ValAsp: 1.575 ± 0.446
5.774ValGlu: 5.774 ± 1.447
2.625ValPhe: 2.625 ± 0.805
1.05ValGly: 1.05 ± 0.504
2.625ValHis: 2.625 ± 0.11
3.675ValIle: 3.675 ± 0.697
3.15ValLys: 3.15 ± 0.462
4.724ValLeu: 4.724 ± 1.845
1.05ValMet: 1.05 ± 0.504
2.625ValAsn: 2.625 ± 0.11
5.774ValPro: 5.774 ± 2.303
2.625ValGln: 2.625 ± 1.828
2.1ValArg: 2.1 ± 0.574
1.05ValSer: 1.05 ± 1.019
4.724ValThr: 4.724 ± 1.81
2.1ValVal: 2.1 ± 1.222
0.525ValTrp: 0.525 ± 0.306
3.675ValTyr: 3.675 ± 1.34
0.0ValXaa: 0.0 ± 0.0
Trp
0.525TrpAla: 0.525 ± 0.306
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.525TrpMet: 0.525 ± 0.306
0.0TrpAsn: 0.0 ± 0.0
1.05TrpPro: 1.05 ± 0.504
0.0TrpGln: 0.0 ± 0.0
2.1TrpArg: 2.1 ± 0.196
0.525TrpSer: 0.525 ± 0.306
0.0TrpThr: 0.0 ± 0.0
1.05TrpVal: 1.05 ± 0.504
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.1TyrAla: 2.1 ± 0.574
0.0TyrCys: 0.0 ± 0.0
4.199TyrAsp: 4.199 ± 2.281
1.575TyrGlu: 1.575 ± 0.501
2.1TyrPhe: 2.1 ± 0.196
0.525TyrGly: 0.525 ± 0.306
2.625TyrHis: 2.625 ± 0.867
2.625TyrIle: 2.625 ± 0.966
2.1TyrLys: 2.1 ± 0.876
5.774TyrLeu: 5.774 ± 1.198
0.0TyrMet: 0.0 ± 0.0
2.625TyrAsn: 2.625 ± 1.828
1.575TyrPro: 1.575 ± 0.917
0.525TyrGln: 0.525 ± 0.306
1.575TyrArg: 1.575 ± 0.564
4.724TyrSer: 4.724 ± 0.782
2.625TyrThr: 2.625 ± 0.11
3.675TyrVal: 3.675 ± 0.697
0.525TyrTrp: 0.525 ± 0.306
3.15TyrTyr: 3.15 ± 1.568
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1906 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski