Amino acid dipepetide frequency for Klebsiella phage ST15-OXA48phi14.1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.401AlaAla: 9.401 ± 1.365
1.247AlaCys: 1.247 ± 0.39
6.907AlaAsp: 6.907 ± 0.784
6.427AlaGlu: 6.427 ± 0.856
2.59AlaPhe: 2.59 ± 0.435
8.058AlaGly: 8.058 ± 1.231
1.055AlaHis: 1.055 ± 0.252
4.125AlaIle: 4.125 ± 0.568
4.988AlaLys: 4.988 ± 0.711
9.689AlaLeu: 9.689 ± 1.356
2.878AlaMet: 2.878 ± 0.524
2.302AlaAsn: 2.302 ± 0.584
2.974AlaPro: 2.974 ± 0.661
2.878AlaGln: 2.878 ± 0.635
6.427AlaArg: 6.427 ± 0.75
6.236AlaSer: 6.236 ± 0.895
5.18AlaThr: 5.18 ± 0.583
7.387AlaVal: 7.387 ± 0.68
1.823AlaTrp: 1.823 ± 0.389
3.07AlaTyr: 3.07 ± 0.515
0.0AlaXaa: 0.0 ± 0.0
Cys
0.863CysAla: 0.863 ± 0.381
0.096CysCys: 0.096 ± 0.09
0.672CysAsp: 0.672 ± 0.239
0.384CysGlu: 0.384 ± 0.158
0.192CysPhe: 0.192 ± 0.191
0.767CysGly: 0.767 ± 0.298
0.384CysHis: 0.384 ± 0.166
0.48CysIle: 0.48 ± 0.232
0.384CysLys: 0.384 ± 0.196
1.343CysLeu: 1.343 ± 0.472
0.192CysMet: 0.192 ± 0.148
0.096CysAsn: 0.096 ± 0.102
0.767CysPro: 0.767 ± 0.315
0.48CysGln: 0.48 ± 0.209
0.863CysArg: 0.863 ± 0.326
0.576CysSer: 0.576 ± 0.26
0.672CysThr: 0.672 ± 0.221
0.48CysVal: 0.48 ± 0.197
0.384CysTrp: 0.384 ± 0.196
0.384CysTyr: 0.384 ± 0.191
0.0CysXaa: 0.0 ± 0.0
Asp
6.811AspAla: 6.811 ± 0.782
0.48AspCys: 0.48 ± 0.208
3.741AspAsp: 3.741 ± 0.583
3.837AspGlu: 3.837 ± 0.474
2.206AspPhe: 2.206 ± 0.483
5.852AspGly: 5.852 ± 0.572
0.767AspHis: 0.767 ± 0.232
3.166AspIle: 3.166 ± 0.599
2.782AspLys: 2.782 ± 0.454
6.044AspLeu: 6.044 ± 0.872
1.055AspMet: 1.055 ± 0.208
2.302AspAsn: 2.302 ± 0.596
2.494AspPro: 2.494 ± 0.484
2.59AspGln: 2.59 ± 0.478
2.59AspArg: 2.59 ± 0.491
3.358AspSer: 3.358 ± 0.444
2.782AspThr: 2.782 ± 0.642
4.797AspVal: 4.797 ± 0.667
0.672AspTrp: 0.672 ± 0.236
2.206AspTyr: 2.206 ± 0.461
0.0AspXaa: 0.0 ± 0.0
Glu
5.756GluAla: 5.756 ± 0.759
0.767GluCys: 0.767 ± 0.327
3.262GluAsp: 3.262 ± 0.625
2.494GluGlu: 2.494 ± 0.568
1.919GluPhe: 1.919 ± 0.434
3.358GluGly: 3.358 ± 0.565
1.247GluHis: 1.247 ± 0.263
3.262GluIle: 3.262 ± 0.547
2.878GluLys: 2.878 ± 0.511
7.195GluLeu: 7.195 ± 0.998
2.015GluMet: 2.015 ± 0.431
3.07GluAsn: 3.07 ± 0.43
2.398GluPro: 2.398 ± 0.551
3.645GluGln: 3.645 ± 0.803
4.317GluArg: 4.317 ± 0.495
2.974GluSer: 2.974 ± 0.569
3.741GluThr: 3.741 ± 0.607
4.221GluVal: 4.221 ± 0.623
0.959GluTrp: 0.959 ± 0.246
1.727GluTyr: 1.727 ± 0.588
0.0GluXaa: 0.0 ± 0.0
Phe
3.358PheAla: 3.358 ± 0.55
0.096PheCys: 0.096 ± 0.1
1.919PheAsp: 1.919 ± 0.438
1.823PheGlu: 1.823 ± 0.397
1.247PhePhe: 1.247 ± 0.329
1.727PheGly: 1.727 ± 0.394
0.576PheHis: 0.576 ± 0.24
1.823PheIle: 1.823 ± 0.47
1.343PheLys: 1.343 ± 0.323
2.686PheLeu: 2.686 ± 0.579
1.055PheMet: 1.055 ± 0.286
2.015PheAsn: 2.015 ± 0.409
1.055PhePro: 1.055 ± 0.304
1.343PheGln: 1.343 ± 0.366
2.686PheArg: 2.686 ± 0.571
3.07PheSer: 3.07 ± 0.55
2.206PheThr: 2.206 ± 0.474
1.535PheVal: 1.535 ± 0.37
0.767PheTrp: 0.767 ± 0.304
0.863PheTyr: 0.863 ± 0.333
0.0PheXaa: 0.0 ± 0.0
Gly
5.276GlyAla: 5.276 ± 0.794
0.576GlyCys: 0.576 ± 0.235
4.701GlyAsp: 4.701 ± 0.466
4.125GlyGlu: 4.125 ± 0.681
3.262GlyPhe: 3.262 ± 0.511
7.291GlyGly: 7.291 ± 1.207
1.535GlyHis: 1.535 ± 0.434
4.029GlyIle: 4.029 ± 0.671
4.797GlyLys: 4.797 ± 0.694
5.948GlyLeu: 5.948 ± 0.727
2.494GlyMet: 2.494 ± 0.504
3.358GlyAsn: 3.358 ± 0.515
1.919GlyPro: 1.919 ± 0.486
2.59GlyGln: 2.59 ± 0.666
3.741GlyArg: 3.741 ± 0.6
3.454GlySer: 3.454 ± 0.525
3.262GlyThr: 3.262 ± 0.495
5.564GlyVal: 5.564 ± 0.782
1.439GlyTrp: 1.439 ± 0.37
1.535GlyTyr: 1.535 ± 0.366
0.0GlyXaa: 0.0 ± 0.0
His
1.727HisAla: 1.727 ± 0.376
0.192HisCys: 0.192 ± 0.129
1.055HisAsp: 1.055 ± 0.362
0.863HisGlu: 0.863 ± 0.305
0.672HisPhe: 0.672 ± 0.284
1.631HisGly: 1.631 ± 0.344
0.767HisHis: 0.767 ± 0.335
0.863HisIle: 0.863 ± 0.297
1.439HisLys: 1.439 ± 0.325
1.247HisLeu: 1.247 ± 0.411
0.672HisMet: 0.672 ± 0.228
0.576HisAsn: 0.576 ± 0.213
0.767HisPro: 0.767 ± 0.254
0.863HisGln: 0.863 ± 0.269
1.439HisArg: 1.439 ± 0.385
1.439HisSer: 1.439 ± 0.367
1.535HisThr: 1.535 ± 0.383
0.959HisVal: 0.959 ± 0.25
0.48HisTrp: 0.48 ± 0.183
0.863HisTyr: 0.863 ± 0.287
0.0HisXaa: 0.0 ± 0.0
Ile
4.797IleAla: 4.797 ± 0.604
0.672IleCys: 0.672 ± 0.27
3.55IleAsp: 3.55 ± 0.478
3.454IleGlu: 3.454 ± 0.596
1.727IlePhe: 1.727 ± 0.484
2.878IleGly: 2.878 ± 0.573
0.959IleHis: 0.959 ± 0.337
2.59IleIle: 2.59 ± 0.348
2.686IleLys: 2.686 ± 0.397
2.782IleLeu: 2.782 ± 0.579
1.823IleMet: 1.823 ± 0.331
3.645IleAsn: 3.645 ± 0.598
2.206IlePro: 2.206 ± 0.585
1.439IleGln: 1.439 ± 0.34
4.509IleArg: 4.509 ± 0.429
3.741IleSer: 3.741 ± 0.662
3.645IleThr: 3.645 ± 0.573
2.398IleVal: 2.398 ± 0.421
0.767IleTrp: 0.767 ± 0.209
1.823IleTyr: 1.823 ± 0.372
0.0IleXaa: 0.0 ± 0.0
Lys
5.372LysAla: 5.372 ± 0.69
0.384LysCys: 0.384 ± 0.165
3.358LysAsp: 3.358 ± 0.587
3.262LysGlu: 3.262 ± 0.482
2.015LysPhe: 2.015 ± 0.397
3.454LysGly: 3.454 ± 0.572
1.343LysHis: 1.343 ± 0.374
2.782LysIle: 2.782 ± 0.458
3.454LysLys: 3.454 ± 0.601
4.509LysLeu: 4.509 ± 0.791
0.959LysMet: 0.959 ± 0.243
2.302LysAsn: 2.302 ± 0.377
2.878LysPro: 2.878 ± 0.524
2.59LysGln: 2.59 ± 0.434
3.837LysArg: 3.837 ± 0.764
2.686LysSer: 2.686 ± 0.582
3.166LysThr: 3.166 ± 0.555
2.015LysVal: 2.015 ± 0.423
1.055LysTrp: 1.055 ± 0.35
1.247LysTyr: 1.247 ± 0.403
0.0LysXaa: 0.0 ± 0.0
Leu
9.881LeuAla: 9.881 ± 0.863
0.863LeuCys: 0.863 ± 0.272
5.564LeuAsp: 5.564 ± 0.732
5.372LeuGlu: 5.372 ± 0.611
2.974LeuPhe: 2.974 ± 0.593
4.509LeuGly: 4.509 ± 0.775
1.151LeuHis: 1.151 ± 0.325
4.701LeuIle: 4.701 ± 0.739
5.468LeuLys: 5.468 ± 0.753
7.962LeuLeu: 7.962 ± 1.044
3.07LeuMet: 3.07 ± 0.593
5.66LeuAsn: 5.66 ± 0.702
3.55LeuPro: 3.55 ± 0.607
4.893LeuGln: 4.893 ± 0.631
6.427LeuArg: 6.427 ± 0.976
6.907LeuSer: 6.907 ± 0.985
5.18LeuThr: 5.18 ± 0.81
4.988LeuVal: 4.988 ± 0.904
1.055LeuTrp: 1.055 ± 0.288
3.262LeuTyr: 3.262 ± 0.613
0.0LeuXaa: 0.0 ± 0.0
Met
4.893MetAla: 4.893 ± 0.626
0.48MetCys: 0.48 ± 0.215
1.151MetAsp: 1.151 ± 0.318
1.535MetGlu: 1.535 ± 0.382
0.863MetPhe: 0.863 ± 0.269
1.247MetGly: 1.247 ± 0.42
0.576MetHis: 0.576 ± 0.232
0.959MetIle: 0.959 ± 0.323
1.535MetLys: 1.535 ± 0.327
1.823MetLeu: 1.823 ± 0.308
1.535MetMet: 1.535 ± 0.609
1.343MetAsn: 1.343 ± 0.393
1.439MetPro: 1.439 ± 0.367
0.576MetGln: 0.576 ± 0.245
1.343MetArg: 1.343 ± 0.368
2.206MetSer: 2.206 ± 0.515
2.398MetThr: 2.398 ± 0.505
1.439MetVal: 1.439 ± 0.387
0.288MetTrp: 0.288 ± 0.155
0.767MetTyr: 0.767 ± 0.287
0.0MetXaa: 0.0 ± 0.0
Asn
3.358AsnAla: 3.358 ± 0.567
0.48AsnCys: 0.48 ± 0.235
2.206AsnAsp: 2.206 ± 0.403
2.878AsnGlu: 2.878 ± 0.433
1.247AsnPhe: 1.247 ± 0.294
3.358AsnGly: 3.358 ± 0.522
1.055AsnHis: 1.055 ± 0.402
2.974AsnIle: 2.974 ± 0.496
1.919AsnLys: 1.919 ± 0.394
3.741AsnLeu: 3.741 ± 0.6
1.151AsnMet: 1.151 ± 0.314
1.823AsnAsn: 1.823 ± 0.381
3.55AsnPro: 3.55 ± 0.635
2.206AsnGln: 2.206 ± 0.391
2.686AsnArg: 2.686 ± 0.548
1.727AsnSer: 1.727 ± 0.461
1.823AsnThr: 1.823 ± 0.41
3.166AsnVal: 3.166 ± 0.676
0.959AsnTrp: 0.959 ± 0.298
1.055AsnTyr: 1.055 ± 0.435
0.0AsnXaa: 0.0 ± 0.0
Pro
4.701ProAla: 4.701 ± 0.601
0.48ProCys: 0.48 ± 0.186
3.262ProAsp: 3.262 ± 0.517
2.686ProGlu: 2.686 ± 0.421
0.863ProPhe: 0.863 ± 0.29
3.454ProGly: 3.454 ± 0.458
1.055ProHis: 1.055 ± 0.294
1.343ProIle: 1.343 ± 0.32
2.111ProLys: 2.111 ± 0.392
3.645ProLeu: 3.645 ± 0.406
0.672ProMet: 0.672 ± 0.233
1.343ProAsn: 1.343 ± 0.463
2.111ProPro: 2.111 ± 0.549
1.535ProGln: 1.535 ± 0.396
1.823ProArg: 1.823 ± 0.335
1.919ProSer: 1.919 ± 0.443
1.631ProThr: 1.631 ± 0.368
3.55ProVal: 3.55 ± 0.491
0.576ProTrp: 0.576 ± 0.229
1.535ProTyr: 1.535 ± 0.441
0.0ProXaa: 0.0 ± 0.0
Gln
4.701GlnAla: 4.701 ± 0.714
0.672GlnCys: 0.672 ± 0.25
2.782GlnAsp: 2.782 ± 0.494
2.206GlnGlu: 2.206 ± 0.417
1.055GlnPhe: 1.055 ± 0.26
3.837GlnGly: 3.837 ± 0.538
0.576GlnHis: 0.576 ± 0.306
2.015GlnIle: 2.015 ± 0.499
1.535GlnLys: 1.535 ± 0.407
4.893GlnLeu: 4.893 ± 0.805
1.823GlnMet: 1.823 ± 0.405
1.727GlnAsn: 1.727 ± 0.485
1.151GlnPro: 1.151 ± 0.326
2.398GlnGln: 2.398 ± 0.511
3.358GlnArg: 3.358 ± 0.643
2.398GlnSer: 2.398 ± 0.471
2.111GlnThr: 2.111 ± 0.428
2.398GlnVal: 2.398 ± 0.453
0.576GlnTrp: 0.576 ± 0.21
0.576GlnTyr: 0.576 ± 0.25
0.0GlnXaa: 0.0 ± 0.0
Arg
5.276ArgAla: 5.276 ± 0.852
0.672ArgCys: 0.672 ± 0.283
3.741ArgAsp: 3.741 ± 0.494
4.509ArgGlu: 4.509 ± 0.824
2.398ArgPhe: 2.398 ± 0.695
3.454ArgGly: 3.454 ± 0.543
1.823ArgHis: 1.823 ± 0.462
4.221ArgIle: 4.221 ± 0.58
4.221ArgLys: 4.221 ± 0.816
7.099ArgLeu: 7.099 ± 0.71
1.631ArgMet: 1.631 ± 0.392
3.07ArgAsn: 3.07 ± 0.535
1.343ArgPro: 1.343 ± 0.257
3.837ArgGln: 3.837 ± 0.54
5.66ArgArg: 5.66 ± 0.762
2.974ArgSer: 2.974 ± 0.475
2.782ArgThr: 2.782 ± 0.401
4.605ArgVal: 4.605 ± 0.743
1.631ArgTrp: 1.631 ± 0.357
1.823ArgTyr: 1.823 ± 0.33
0.0ArgXaa: 0.0 ± 0.0
Ser
6.14SerAla: 6.14 ± 0.599
0.288SerCys: 0.288 ± 0.133
2.974SerAsp: 2.974 ± 0.454
3.741SerGlu: 3.741 ± 0.595
2.398SerPhe: 2.398 ± 0.368
4.509SerGly: 4.509 ± 0.733
1.055SerHis: 1.055 ± 0.464
2.782SerIle: 2.782 ± 0.444
2.974SerLys: 2.974 ± 0.643
6.236SerLeu: 6.236 ± 0.8
1.535SerMet: 1.535 ± 0.355
2.59SerAsn: 2.59 ± 0.454
2.398SerPro: 2.398 ± 0.408
2.59SerGln: 2.59 ± 0.56
3.454SerArg: 3.454 ± 0.518
2.878SerSer: 2.878 ± 0.469
3.55SerThr: 3.55 ± 0.528
4.317SerVal: 4.317 ± 0.632
1.055SerTrp: 1.055 ± 0.271
1.823SerTyr: 1.823 ± 0.464
0.0SerXaa: 0.0 ± 0.0
Thr
4.509ThrAla: 4.509 ± 0.699
0.288ThrCys: 0.288 ± 0.146
3.837ThrAsp: 3.837 ± 0.583
3.645ThrGlu: 3.645 ± 0.512
1.823ThrPhe: 1.823 ± 0.438
4.893ThrGly: 4.893 ± 0.927
1.439ThrHis: 1.439 ± 0.337
2.494ThrIle: 2.494 ± 0.459
2.111ThrLys: 2.111 ± 0.485
5.852ThrLeu: 5.852 ± 0.485
0.863ThrMet: 0.863 ± 0.297
2.015ThrAsn: 2.015 ± 0.384
2.878ThrPro: 2.878 ± 0.465
1.727ThrGln: 1.727 ± 0.359
3.837ThrArg: 3.837 ± 0.53
3.454ThrSer: 3.454 ± 0.557
4.413ThrThr: 4.413 ± 0.732
4.988ThrVal: 4.988 ± 0.629
0.288ThrTrp: 0.288 ± 0.158
1.727ThrTyr: 1.727 ± 0.494
0.0ThrXaa: 0.0 ± 0.0
Val
5.948ValAla: 5.948 ± 0.706
0.672ValCys: 0.672 ± 0.235
3.645ValAsp: 3.645 ± 0.812
3.933ValGlu: 3.933 ± 0.659
1.919ValPhe: 1.919 ± 0.315
3.933ValGly: 3.933 ± 0.898
1.247ValHis: 1.247 ± 0.276
5.084ValIle: 5.084 ± 0.763
4.221ValLys: 4.221 ± 0.734
5.852ValLeu: 5.852 ± 0.774
2.015ValMet: 2.015 ± 0.539
2.782ValAsn: 2.782 ± 0.706
2.974ValPro: 2.974 ± 0.475
2.974ValGln: 2.974 ± 0.585
3.55ValArg: 3.55 ± 0.483
4.413ValSer: 4.413 ± 0.597
4.317ValThr: 4.317 ± 0.695
4.413ValVal: 4.413 ± 0.662
0.767ValTrp: 0.767 ± 0.258
1.535ValTyr: 1.535 ± 0.387
0.0ValXaa: 0.0 ± 0.0
Trp
1.439TrpAla: 1.439 ± 0.327
0.288TrpCys: 0.288 ± 0.179
0.672TrpAsp: 0.672 ± 0.304
1.919TrpGlu: 1.919 ± 0.383
0.48TrpPhe: 0.48 ± 0.174
0.576TrpGly: 0.576 ± 0.216
0.672TrpHis: 0.672 ± 0.222
0.863TrpIle: 0.863 ± 0.333
0.767TrpLys: 0.767 ± 0.232
1.823TrpLeu: 1.823 ± 0.436
0.384TrpMet: 0.384 ± 0.194
0.192TrpAsn: 0.192 ± 0.126
0.576TrpPro: 0.576 ± 0.221
0.576TrpGln: 0.576 ± 0.177
1.247TrpArg: 1.247 ± 0.318
0.863TrpSer: 0.863 ± 0.302
0.672TrpThr: 0.672 ± 0.285
1.055TrpVal: 1.055 ± 0.311
0.384TrpTrp: 0.384 ± 0.17
0.767TrpTyr: 0.767 ± 0.272
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.439TyrAla: 1.439 ± 0.296
0.767TyrCys: 0.767 ± 0.235
1.535TyrAsp: 1.535 ± 0.327
2.206TyrGlu: 2.206 ± 0.477
1.343TyrPhe: 1.343 ± 0.49
2.111TyrGly: 2.111 ± 0.41
0.767TyrHis: 0.767 ± 0.291
1.535TyrIle: 1.535 ± 0.359
1.055TyrLys: 1.055 ± 0.24
3.07TyrLeu: 3.07 ± 0.571
0.48TyrMet: 0.48 ± 0.178
1.151TyrAsn: 1.151 ± 0.272
0.863TyrPro: 0.863 ± 0.304
1.055TyrGln: 1.055 ± 0.358
2.974TyrArg: 2.974 ± 0.388
2.015TyrSer: 2.015 ± 0.606
2.015TyrThr: 2.015 ± 0.459
1.919TyrVal: 1.919 ± 0.393
0.288TyrTrp: 0.288 ± 0.163
0.863TyrTyr: 0.863 ± 0.301
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 46 proteins (10425 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski