Amino acid dipepetide frequency for Leersia perrieri

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.384AlaAla: 13.384 ± 0.074	1.523AlaCys: 1.523 ± 0.01	4.183AlaAsp: 4.183 ± 0.02	4.782AlaGlu: 4.782 ± 0.022	2.939AlaPhe: 2.939 ± 0.015	6.379AlaGly: 6.379 ± 0.031	1.662AlaHis: 1.662 ± 0.012	3.841AlaIle: 3.841 ± 0.016	3.74AlaLys: 3.74 ± 0.017	7.492AlaLeu: 7.492 ± 0.026	2.298AlaMet: 2.298 ± 0.016	2.621AlaAsn: 2.621 ± 0.015	4.239AlaPro: 4.239 ± 0.022	2.332AlaGln: 2.332 ± 0.014	4.97AlaArg: 4.97 ± 0.025	7.113AlaSer: 7.113 ± 0.024	4.699AlaThr: 4.699 ± 0.021	6.652AlaVal: 6.652 ± 0.029	0.951AlaTrp: 0.951 ± 0.009	1.908AlaTyr: 1.908 ± 0.012	0.001AlaXaa: 0.001 ± 0.0
Cys	1.275CysAla: 1.275 ± 0.009	0.596CysCys: 0.596 ± 0.008	0.912CysAsp: 0.912 ± 0.008	0.82CysGlu: 0.82 ± 0.008	0.821CysPhe: 0.821 ± 0.008	1.494CysGly: 1.494 ± 0.011	0.528CysHis: 0.528 ± 0.007	0.96CysIle: 0.96 ± 0.009	0.974CysLys: 0.974 ± 0.009	1.831CysLeu: 1.831 ± 0.012	0.439CysMet: 0.439 ± 0.005	0.764CysAsn: 0.764 ± 0.006	1.011CysPro: 1.011 ± 0.009	0.59CysGln: 0.59 ± 0.007	1.275CysArg: 1.275 ± 0.01	1.858CysSer: 1.858 ± 0.012	0.937CysThr: 0.937 ± 0.008	1.128CysVal: 1.128 ± 0.01	0.25CysTrp: 0.25 ± 0.004	0.537CysTyr: 0.537 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	4.647AspAla: 4.647 ± 0.024	0.95AspCys: 0.95 ± 0.008	4.365AspAsp: 4.365 ± 0.025	4.028AspGlu: 4.028 ± 0.021	2.024AspPhe: 2.024 ± 0.01	4.722AspGly: 4.722 ± 0.022	1.286AspHis: 1.286 ± 0.009	2.846AspIle: 2.846 ± 0.017	2.512AspLys: 2.512 ± 0.015	4.978AspLeu: 4.978 ± 0.024	1.45AspMet: 1.45 ± 0.011	1.951AspAsn: 1.951 ± 0.014	2.64AspPro: 2.64 ± 0.014	1.651AspGln: 1.651 ± 0.012	2.668AspArg: 2.668 ± 0.015	3.776AspSer: 3.776 ± 0.019	2.299AspThr: 2.299 ± 0.013	3.884AspVal: 3.884 ± 0.016	0.697AspTrp: 0.697 ± 0.006	1.462AspTyr: 1.462 ± 0.01	0.0AspXaa: 0.0 ± 0.0
Glu	5.162GluAla: 5.162 ± 0.022	0.891GluCys: 0.891 ± 0.01	3.688GluAsp: 3.688 ± 0.016	5.902GluGlu: 5.902 ± 0.033	2.068GluPhe: 2.068 ± 0.014	3.604GluGly: 3.604 ± 0.016	1.397GluHis: 1.397 ± 0.01	3.186GluIle: 3.186 ± 0.015	3.874GluLys: 3.874 ± 0.019	5.934GluLeu: 5.934 ± 0.026	1.745GluMet: 1.745 ± 0.01	2.401GluAsn: 2.401 ± 0.015	2.187GluPro: 2.187 ± 0.015	2.21GluGln: 2.21 ± 0.012	3.566GluArg: 3.566 ± 0.017	3.901GluSer: 3.901 ± 0.019	2.645GluThr: 2.645 ± 0.014	4.054GluVal: 4.054 ± 0.016	0.743GluTrp: 0.743 ± 0.008	1.524GluTyr: 1.524 ± 0.011	0.0GluXaa: 0.0 ± 0.0
Phe	2.791PheAla: 2.791 ± 0.015	0.784PheCys: 0.784 ± 0.007	2.214PheAsp: 2.214 ± 0.011	1.873PheGlu: 1.873 ± 0.01	1.691PhePhe: 1.691 ± 0.013	2.894PheGly: 2.894 ± 0.016	1.014PheHis: 1.014 ± 0.009	1.695PheIle: 1.695 ± 0.011	1.521PheLys: 1.521 ± 0.01	3.876PheLeu: 3.876 ± 0.016	0.885PheMet: 0.885 ± 0.008	1.356PheAsn: 1.356 ± 0.011	1.909PhePro: 1.909 ± 0.011	1.261PheGln: 1.261 ± 0.009	2.057PheArg: 2.057 ± 0.011	3.36PheSer: 3.36 ± 0.016	1.791PheThr: 1.791 ± 0.011	2.667PheVal: 2.667 ± 0.015	0.513PheTrp: 0.513 ± 0.006	1.075PheTyr: 1.075 ± 0.009	0.0PheXaa: 0.0 ± 0.0
Gly	5.56GlyAla: 5.56 ± 0.028	1.469GlyCys: 1.469 ± 0.013	4.214GlyAsp: 4.214 ± 0.018	4.181GlyGlu: 4.181 ± 0.017	2.859GlyPhe: 2.859 ± 0.017	8.217GlyGly: 8.217 ± 0.051	1.733GlyHis: 1.733 ± 0.011	3.344GlyIle: 3.344 ± 0.018	3.664GlyLys: 3.664 ± 0.015	5.795GlyLeu: 5.795 ± 0.021	1.67GlyMet: 1.67 ± 0.011	2.878GlyAsn: 2.878 ± 0.019	2.502GlyPro: 2.502 ± 0.015	2.096GlyGln: 2.096 ± 0.013	4.525GlyArg: 4.525 ± 0.021	5.865GlySer: 5.865 ± 0.025	3.323GlyThr: 3.323 ± 0.017	4.723GlyVal: 4.723 ± 0.021	0.977GlyTrp: 0.977 ± 0.009	2.051GlyTyr: 2.051 ± 0.014	0.001GlyXaa: 0.001 ± 0.0
His	1.861HisAla: 1.861 ± 0.011	0.527HisCys: 0.527 ± 0.006	1.315HisAsp: 1.315 ± 0.009	1.277HisGlu: 1.277 ± 0.01	0.937HisPhe: 0.937 ± 0.007	2.112HisGly: 2.112 ± 0.013	1.118HisHis: 1.118 ± 0.012	1.135HisIle: 1.135 ± 0.009	1.042HisLys: 1.042 ± 0.01	2.58HisLeu: 2.58 ± 0.016	0.572HisMet: 0.572 ± 0.005	0.874HisAsn: 0.874 ± 0.008	1.503HisPro: 1.503 ± 0.01	0.96HisGln: 0.96 ± 0.009	1.721HisArg: 1.721 ± 0.011	1.711HisSer: 1.711 ± 0.011	1.007HisThr: 1.007 ± 0.008	1.639HisVal: 1.639 ± 0.01	0.3HisTrp: 0.3 ± 0.005	0.662HisTyr: 0.662 ± 0.007	0.001HisXaa: 0.001 ± 0.0
Ile	3.675IleAla: 3.675 ± 0.016	1.001IleCys: 1.001 ± 0.009	2.708IleAsp: 2.708 ± 0.015	2.644IleGlu: 2.644 ± 0.015	1.814IlePhe: 1.814 ± 0.011	3.226IleGly: 3.226 ± 0.016	1.222IleHis: 1.222 ± 0.009	2.395IleIle: 2.395 ± 0.014	2.391IleLys: 2.391 ± 0.013	4.605IleLeu: 4.605 ± 0.023	1.046IleMet: 1.046 ± 0.008	1.852IleAsn: 1.852 ± 0.015	2.628IlePro: 2.628 ± 0.018	1.646IleGln: 1.646 ± 0.012	2.524IleArg: 2.524 ± 0.014	4.165IleSer: 4.165 ± 0.02	2.418IleThr: 2.418 ± 0.014	3.19IleVal: 3.19 ± 0.015	0.613IleTrp: 0.613 ± 0.006	1.3IleTyr: 1.3 ± 0.009	0.0IleXaa: 0.0 ± 0.0
Lys	3.756LysAla: 3.756 ± 0.017	0.832LysCys: 0.832 ± 0.008	2.776LysAsp: 2.776 ± 0.014	3.78LysGlu: 3.78 ± 0.021	1.686LysPhe: 1.686 ± 0.011	3.109LysGly: 3.109 ± 0.014	1.2LysHis: 1.2 ± 0.01	2.658LysIle: 2.658 ± 0.015	3.707LysLys: 3.707 ± 0.024	5.071LysLeu: 5.071 ± 0.022	1.29LysMet: 1.29 ± 0.01	2.066LysAsn: 2.066 ± 0.013	2.363LysPro: 2.363 ± 0.015	1.959LysGln: 1.959 ± 0.013	3.168LysArg: 3.168 ± 0.014	3.646LysSer: 3.646 ± 0.019	2.324LysThr: 2.324 ± 0.013	3.263LysVal: 3.263 ± 0.017	0.607LysTrp: 0.607 ± 0.007	1.366LysTyr: 1.366 ± 0.009	0.0LysXaa: 0.0 ± 0.0
Leu	7.979LeuAla: 7.979 ± 0.029	1.829LeuCys: 1.829 ± 0.013	5.12LeuAsp: 5.12 ± 0.02	5.707LeuGlu: 5.707 ± 0.026	3.456LeuPhe: 3.456 ± 0.018	5.713LeuGly: 5.713 ± 0.018	2.789LeuHis: 2.789 ± 0.016	3.935LeuIle: 3.935 ± 0.021	4.915LeuLys: 4.915 ± 0.025	10.581LeuLeu: 10.581 ± 0.036	2.061LeuMet: 2.061 ± 0.013	3.188LeuAsn: 3.188 ± 0.017	5.779LeuPro: 5.779 ± 0.025	4.083LeuGln: 4.083 ± 0.021	6.245LeuArg: 6.245 ± 0.023	7.862LeuSer: 7.862 ± 0.032	4.391LeuThr: 4.391 ± 0.02	6.485LeuVal: 6.485 ± 0.024	1.118LeuTrp: 1.118 ± 0.009	2.326LeuTyr: 2.326 ± 0.014	0.001LeuXaa: 0.001 ± 0.0
Met	2.711MetAla: 2.711 ± 0.015	0.36MetCys: 0.36 ± 0.005	1.496MetAsp: 1.496 ± 0.01	1.905MetGlu: 1.905 ± 0.012	0.786MetPhe: 0.786 ± 0.007	1.531MetGly: 1.531 ± 0.011	0.574MetHis: 0.574 ± 0.006	1.052MetIle: 1.052 ± 0.008	1.33MetLys: 1.33 ± 0.009	2.287MetLeu: 2.287 ± 0.014	0.722MetMet: 0.722 ± 0.008	0.872MetAsn: 0.872 ± 0.008	1.281MetPro: 1.281 ± 0.009	0.921MetGln: 0.921 ± 0.008	1.367MetArg: 1.367 ± 0.009	1.811MetSer: 1.811 ± 0.011	1.09MetThr: 1.09 ± 0.009	1.729MetVal: 1.729 ± 0.011	0.29MetTrp: 0.29 ± 0.005	0.614MetTyr: 0.614 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.704AsnAla: 2.704 ± 0.015	0.742AsnCys: 0.742 ± 0.007	1.848AsnAsp: 1.848 ± 0.011	1.957AsnGlu: 1.957 ± 0.012	1.5AsnPhe: 1.5 ± 0.011	2.949AsnGly: 2.949 ± 0.017	0.94AsnHis: 0.94 ± 0.007	2.159AsnIle: 2.159 ± 0.014	1.922AsnLys: 1.922 ± 0.012	3.872AsnLeu: 3.872 ± 0.027	1.019AsnMet: 1.019 ± 0.009	1.863AsnAsn: 1.863 ± 0.016	1.962AsnPro: 1.962 ± 0.013	1.316AsnGln: 1.316 ± 0.01	1.806AsnArg: 1.806 ± 0.012	3.067AsnSer: 3.067 ± 0.016	1.815AsnThr: 1.815 ± 0.012	2.364AsnVal: 2.364 ± 0.013	0.463AsnTrp: 0.463 ± 0.006	1.095AsnTyr: 1.095 ± 0.009	0.0AsnXaa: 0.0 ± 0.0
Pro	4.909ProAla: 4.909 ± 0.026	0.932ProCys: 0.932 ± 0.009	2.709ProAsp: 2.709 ± 0.016	3.189ProGlu: 3.189 ± 0.015	1.897ProPhe: 1.897 ± 0.012	3.036ProGly: 3.036 ± 0.016	1.238ProHis: 1.238 ± 0.009	2.027ProIle: 2.027 ± 0.012	2.282ProLys: 2.282 ± 0.014	4.485ProLeu: 4.485 ± 0.021	1.093ProMet: 1.093 ± 0.008	1.929ProAsn: 1.929 ± 0.013	5.574ProPro: 5.574 ± 0.045	1.72ProGln: 1.72 ± 0.013	3.151ProArg: 3.151 ± 0.02	5.452ProSer: 5.452 ± 0.026	2.783ProThr: 2.783 ± 0.016	3.349ProVal: 3.349 ± 0.016	0.671ProTrp: 0.671 ± 0.007	1.302ProTyr: 1.302 ± 0.011	0.002ProXaa: 0.002 ± 0.0
Gln	2.509GlnAla: 2.509 ± 0.015	0.594GlnCys: 0.594 ± 0.006	1.582GlnAsp: 1.582 ± 0.012	2.271GlnGlu: 2.271 ± 0.016	1.209GlnPhe: 1.209 ± 0.01	2.066GlnGly: 2.066 ± 0.013	0.985GlnHis: 0.985 ± 0.009	1.702GlnIle: 1.702 ± 0.012	1.913GlnLys: 1.913 ± 0.012	3.52GlnLeu: 3.52 ± 0.021	0.937GlnMet: 0.937 ± 0.008	1.399GlnAsn: 1.399 ± 0.011	1.852GlnPro: 1.852 ± 0.015	2.188GlnGln: 2.188 ± 0.025	2.175GlnArg: 2.175 ± 0.013	2.495GlnSer: 2.495 ± 0.017	1.483GlnThr: 1.483 ± 0.011	2.132GlnVal: 2.132 ± 0.012	0.455GlnTrp: 0.455 ± 0.005	0.894GlnTyr: 0.894 ± 0.008	0.0GlnXaa: 0.0 ± 0.0
Arg	4.596ArgAla: 4.596 ± 0.023	1.279ArgCys: 1.279 ± 0.01	2.975ArgAsp: 2.975 ± 0.015	3.407ArgGlu: 3.407 ± 0.017	2.227ArgPhe: 2.227 ± 0.011	3.991ArgGly: 3.991 ± 0.019	1.676ArgHis: 1.676 ± 0.012	2.763ArgIle: 2.763 ± 0.014	3.358ArgLys: 3.358 ± 0.016	5.949ArgLeu: 5.949 ± 0.022	1.517ArgMet: 1.517 ± 0.01	2.189ArgAsn: 2.189 ± 0.014	3.071ArgPro: 3.071 ± 0.017	2.036ArgGln: 2.036 ± 0.014	6.376ArgArg: 6.376 ± 0.031	4.829ArgSer: 4.829 ± 0.022	2.59ArgThr: 2.59 ± 0.012	3.708ArgVal: 3.708 ± 0.017	0.984ArgTrp: 0.984 ± 0.008	1.565ArgTyr: 1.565 ± 0.011	0.001ArgXaa: 0.001 ± 0.0
Ser	6.333SerAla: 6.333 ± 0.023	1.714SerCys: 1.714 ± 0.011	4.159SerAsp: 4.159 ± 0.021	4.063SerGlu: 4.063 ± 0.019	3.324SerPhe: 3.324 ± 0.016	5.929SerGly: 5.929 ± 0.024	1.819SerHis: 1.819 ± 0.012	3.863SerIle: 3.863 ± 0.019	3.905SerLys: 3.905 ± 0.019	7.903SerLeu: 7.903 ± 0.03	2.027SerMet: 2.027 ± 0.011	3.273SerAsn: 3.273 ± 0.018	5.116SerPro: 5.116 ± 0.026	2.492SerGln: 2.492 ± 0.016	4.689SerArg: 4.689 ± 0.02	10.49SerSer: 10.49 ± 0.039	4.614SerThr: 4.614 ± 0.02	4.938SerVal: 4.938 ± 0.017	1.136SerTrp: 1.136 ± 0.01	2.161SerTyr: 2.161 ± 0.013	0.001SerXaa: 0.001 ± 0.0
Thr	4.437ThrAla: 4.437 ± 0.02	0.921ThrCys: 0.921 ± 0.007	2.383ThrAsp: 2.383 ± 0.014	2.632ThrGlu: 2.632 ± 0.014	1.799ThrPhe: 1.799 ± 0.012	3.488ThrGly: 3.488 ± 0.016	0.988ThrHis: 0.988 ± 0.008	2.467ThrIle: 2.467 ± 0.014	2.311ThrLys: 2.311 ± 0.014	4.349ThrLeu: 4.349 ± 0.018	1.262ThrMet: 1.262 ± 0.009	1.875ThrAsn: 1.875 ± 0.011	2.834ThrPro: 2.834 ± 0.016	1.356ThrGln: 1.356 ± 0.01	2.586ThrArg: 2.586 ± 0.013	4.364ThrSer: 4.364 ± 0.017	3.285ThrThr: 3.285 ± 0.018	3.541ThrVal: 3.541 ± 0.017	0.62ThrTrp: 0.62 ± 0.006	1.326ThrTyr: 1.326 ± 0.011	0.0ThrXaa: 0.0 ± 0.0
Val	6.596ValAla: 6.596 ± 0.028	1.182ValCys: 1.182 ± 0.01	4.01ValAsp: 4.01 ± 0.016	4.147ValGlu: 4.147 ± 0.015	2.57ValPhe: 2.57 ± 0.015	4.392ValGly: 4.392 ± 0.021	1.661ValHis: 1.661 ± 0.01	3.083ValIle: 3.083 ± 0.014	3.239ValLys: 3.239 ± 0.015	6.538ValLeu: 6.538 ± 0.022	1.587ValMet: 1.587 ± 0.011	2.243ValAsn: 2.243 ± 0.012	3.5ValPro: 3.5 ± 0.015	2.242ValGln: 2.242 ± 0.011	3.699ValArg: 3.699 ± 0.016	5.151ValSer: 5.151 ± 0.018	3.404ValThr: 3.404 ± 0.016	5.674ValVal: 5.674 ± 0.026	0.817ValTrp: 0.817 ± 0.008	1.849ValTyr: 1.849 ± 0.012	0.0ValXaa: 0.0 ± 0.0
Trp	0.929TrpAla: 0.929 ± 0.009	0.262TrpCys: 0.262 ± 0.005	0.676TrpAsp: 0.676 ± 0.007	0.736TrpGlu: 0.736 ± 0.007	0.485TrpPhe: 0.485 ± 0.006	0.757TrpGly: 0.757 ± 0.009	0.314TrpHis: 0.314 ± 0.004	0.64TrpIle: 0.64 ± 0.006	0.76TrpLys: 0.76 ± 0.007	1.253TrpLeu: 1.253 ± 0.011	0.367TrpMet: 0.367 ± 0.005	0.583TrpAsn: 0.583 ± 0.007	0.578TrpPro: 0.578 ± 0.007	0.444TrpGln: 0.444 ± 0.005	1.045TrpArg: 1.045 ± 0.008	0.994TrpSer: 0.994 ± 0.01	0.646TrpThr: 0.646 ± 0.006	0.796TrpVal: 0.796 ± 0.008	0.256TrpTrp: 0.256 ± 0.004	0.33TrpTyr: 0.33 ± 0.004	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.891TyrAla: 1.891 ± 0.013	0.612TyrCys: 0.612 ± 0.006	1.502TyrAsp: 1.502 ± 0.011	1.38TyrGlu: 1.38 ± 0.011	1.133TyrPhe: 1.133 ± 0.009	2.038TyrGly: 2.038 ± 0.015	0.713TyrHis: 0.713 ± 0.007	1.316TyrIle: 1.316 ± 0.009	1.267TyrLys: 1.267 ± 0.01	2.666TyrLeu: 2.666 ± 0.013	0.742TyrMet: 0.742 ± 0.007	1.182TyrAsn: 1.182 ± 0.009	1.202TyrPro: 1.202 ± 0.01	0.856TyrGln: 0.856 ± 0.008	1.475TyrArg: 1.475 ± 0.009	2.035TyrSer: 2.035 ± 0.012	1.278TyrThr: 1.278 ± 0.01	1.667TyrVal: 1.667 ± 0.011	0.392TyrTrp: 0.392 ± 0.005	0.942TyrTyr: 0.942 ± 0.009	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.018XaaXaa: 0.018 ± 0.003

Statistics based on 36779 proteins (16268560 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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