Amino acid dipepetide frequency for Garlic virus B

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.749AlaAla: 5.749 ± 1.582
1.916AlaCys: 1.916 ± 0.595
2.3AlaAsp: 2.3 ± 1.105
3.833AlaGlu: 3.833 ± 0.953
3.45AlaPhe: 3.45 ± 0.543
3.833AlaGly: 3.833 ± 1.269
2.3AlaHis: 2.3 ± 1.075
3.066AlaIle: 3.066 ± 1.179
6.133AlaLys: 6.133 ± 1.333
9.966AlaLeu: 9.966 ± 2.787
1.916AlaMet: 1.916 ± 1.064
3.833AlaAsn: 3.833 ± 0.861
3.066AlaPro: 3.066 ± 1.574
4.216AlaGln: 4.216 ± 1.774
3.45AlaArg: 3.45 ± 1.215
3.833AlaSer: 3.833 ± 1.572
5.366AlaThr: 5.366 ± 1.829
3.066AlaVal: 3.066 ± 0.59
0.767AlaTrp: 0.767 ± 0.693
3.45AlaTyr: 3.45 ± 1.419
0.0AlaXaa: 0.0 ± 0.0
Cys
0.767CysAla: 0.767 ± 0.52
0.0CysCys: 0.0 ± 0.0
1.15CysAsp: 1.15 ± 0.638
1.15CysGlu: 1.15 ± 0.436
0.767CysPhe: 0.767 ± 0.52
2.683CysGly: 2.683 ± 1.531
0.383CysHis: 0.383 ± 0.213
0.383CysIle: 0.383 ± 0.617
0.767CysLys: 0.767 ± 0.52
2.3CysLeu: 2.3 ± 1.137
0.383CysMet: 0.383 ± 0.498
0.383CysAsn: 0.383 ± 0.213
0.767CysPro: 0.767 ± 0.419
1.15CysGln: 1.15 ± 0.436
0.767CysArg: 0.767 ± 0.419
0.767CysSer: 0.767 ± 0.554
0.767CysThr: 0.767 ± 0.501
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.533CysTyr: 1.533 ± 1.002
0.0CysXaa: 0.0 ± 0.0
Asp
2.683AspAla: 2.683 ± 0.712
2.3AspCys: 2.3 ± 0.992
5.749AspAsp: 5.749 ± 1.766
5.749AspGlu: 5.749 ± 1.722
2.683AspPhe: 2.683 ± 0.768
3.833AspGly: 3.833 ± 1.579
2.3AspHis: 2.3 ± 0.951
3.066AspIle: 3.066 ± 0.948
3.066AspLys: 3.066 ± 1.702
7.282AspLeu: 7.282 ± 2.277
1.15AspMet: 1.15 ± 0.638
3.066AspAsn: 3.066 ± 1.179
2.683AspPro: 2.683 ± 1.021
3.066AspGln: 3.066 ± 0.706
2.683AspArg: 2.683 ± 0.36
4.599AspSer: 4.599 ± 1.434
3.45AspThr: 3.45 ± 1.173
2.3AspVal: 2.3 ± 0.566
0.383AspTrp: 0.383 ± 0.213
3.066AspTyr: 3.066 ± 1.384
0.0AspXaa: 0.0 ± 0.0
Glu
4.216GluAla: 4.216 ± 0.699
1.15GluCys: 1.15 ± 0.436
3.066GluAsp: 3.066 ± 1.384
3.45GluGlu: 3.45 ± 0.543
2.3GluPhe: 2.3 ± 0.836
3.45GluGly: 3.45 ± 0.602
0.383GluHis: 0.383 ± 0.213
3.833GluIle: 3.833 ± 1.637
2.683GluLys: 2.683 ± 1.489
5.366GluLeu: 5.366 ± 0.998
0.767GluMet: 0.767 ± 0.752
1.916GluAsn: 1.916 ± 0.667
2.3GluPro: 2.3 ± 0.833
1.916GluGln: 1.916 ± 0.585
3.833GluArg: 3.833 ± 1.616
5.749GluSer: 5.749 ± 1.264
4.599GluThr: 4.599 ± 1.106
3.066GluVal: 3.066 ± 0.969
0.383GluTrp: 0.383 ± 0.516
0.767GluTyr: 0.767 ± 0.45
0.0GluXaa: 0.0 ± 0.0
Phe
3.066PheAla: 3.066 ± 1.118
0.767PheCys: 0.767 ± 0.501
2.3PheAsp: 2.3 ± 0.555
3.45PheGlu: 3.45 ± 0.92
1.15PhePhe: 1.15 ± 0.941
1.15PheGly: 1.15 ± 0.638
1.533PheHis: 1.533 ± 0.517
1.533PheIle: 1.533 ± 0.484
2.3PheLys: 2.3 ± 0.659
3.066PheLeu: 3.066 ± 0.831
1.533PheMet: 1.533 ± 0.667
2.3PheAsn: 2.3 ± 0.696
1.916PhePro: 1.916 ± 0.66
2.3PheGln: 2.3 ± 1.518
1.916PheArg: 1.916 ± 0.93
2.683PheSer: 2.683 ± 1.007
3.833PheThr: 3.833 ± 1.658
2.3PheVal: 2.3 ± 0.871
0.0PheTrp: 0.0 ± 0.0
1.15PheTyr: 1.15 ± 0.638
0.0PheXaa: 0.0 ± 0.0
Gly
4.216GlyAla: 4.216 ± 1.626
1.15GlyCys: 1.15 ± 0.436
4.216GlyAsp: 4.216 ± 2.072
2.3GlyGlu: 2.3 ± 1.277
1.15GlyPhe: 1.15 ± 0.675
3.45GlyGly: 3.45 ± 1.222
1.916GlyHis: 1.916 ± 0.592
2.3GlyIle: 2.3 ± 0.836
3.833GlyLys: 3.833 ± 1.073
4.216GlyLeu: 4.216 ± 0.861
1.533GlyMet: 1.533 ± 1.002
2.3GlyAsn: 2.3 ± 0.65
2.683GlyPro: 2.683 ± 1.337
1.533GlyGln: 1.533 ± 0.688
2.3GlyArg: 2.3 ± 0.602
0.767GlySer: 0.767 ± 0.802
4.216GlyThr: 4.216 ± 0.982
1.533GlyVal: 1.533 ± 0.9
0.767GlyTrp: 0.767 ± 0.426
1.916GlyTyr: 1.916 ± 0.571
0.0GlyXaa: 0.0 ± 0.0
His
3.066HisAla: 3.066 ± 0.886
0.767HisCys: 0.767 ± 0.554
0.767HisAsp: 0.767 ± 0.419
2.3HisGlu: 2.3 ± 0.653
2.683HisPhe: 2.683 ± 0.822
1.533HisGly: 1.533 ± 0.517
0.767HisHis: 0.767 ± 0.419
2.3HisIle: 2.3 ± 1.831
0.767HisLys: 0.767 ± 1.032
3.066HisLeu: 3.066 ± 1.162
0.0HisMet: 0.0 ± 0.0
0.767HisAsn: 0.767 ± 0.501
1.533HisPro: 1.533 ± 1.002
2.3HisGln: 2.3 ± 0.732
1.533HisArg: 1.533 ± 1.276
3.833HisSer: 3.833 ± 1.1
1.15HisThr: 1.15 ± 0.681
2.683HisVal: 2.683 ± 1.922
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.833IleAla: 3.833 ± 0.569
0.767IleCys: 0.767 ± 0.554
1.15IleAsp: 1.15 ± 0.638
2.683IleGlu: 2.683 ± 0.712
1.533IlePhe: 1.533 ± 0.517
2.3IleGly: 2.3 ± 0.456
3.066IleHis: 3.066 ± 1.999
3.066IleIle: 3.066 ± 0.535
3.066IleLys: 3.066 ± 0.706
5.749IleLeu: 5.749 ± 3.282
1.15IleMet: 1.15 ± 0.55
2.3IleAsn: 2.3 ± 0.734
1.916IlePro: 1.916 ± 0.419
3.833IleGln: 3.833 ± 1.72
3.066IleArg: 3.066 ± 1.015
3.066IleSer: 3.066 ± 1.162
3.45IleThr: 3.45 ± 0.881
4.216IleVal: 4.216 ± 0.944
0.0IleTrp: 0.0 ± 0.0
1.15IleTyr: 1.15 ± 0.757
0.0IleXaa: 0.0 ± 0.0
Lys
4.983LysAla: 4.983 ± 1.878
0.767LysCys: 0.767 ± 0.908
4.216LysAsp: 4.216 ± 1.818
1.916LysGlu: 1.916 ± 1.148
2.3LysPhe: 2.3 ± 1.007
1.533LysGly: 1.533 ± 1.128
2.3LysHis: 2.3 ± 0.836
3.066LysIle: 3.066 ± 1.029
2.3LysLys: 2.3 ± 1.277
7.666LysLeu: 7.666 ± 2.434
1.15LysMet: 1.15 ± 0.55
0.767LysAsn: 0.767 ± 0.419
4.599LysPro: 4.599 ± 1.216
1.15LysGln: 1.15 ± 0.55
4.216LysArg: 4.216 ± 1.82
3.833LysSer: 3.833 ± 1.239
4.983LysThr: 4.983 ± 2.113
1.916LysVal: 1.916 ± 0.66
0.767LysTrp: 0.767 ± 0.426
1.15LysTyr: 1.15 ± 0.418
0.0LysXaa: 0.0 ± 0.0
Leu
8.049LeuAla: 8.049 ± 0.721
0.767LeuCys: 0.767 ± 0.419
8.432LeuAsp: 8.432 ± 2.186
4.599LeuGlu: 4.599 ± 1.191
4.599LeuPhe: 4.599 ± 1.661
3.833LeuGly: 3.833 ± 2.006
3.45LeuHis: 3.45 ± 2.406
7.666LeuIle: 7.666 ± 3.167
4.216LeuLys: 4.216 ± 0.907
8.049LeuLeu: 8.049 ± 1.863
3.066LeuMet: 3.066 ± 0.639
5.366LeuAsn: 5.366 ± 2.486
8.432LeuPro: 8.432 ± 1.766
4.599LeuGln: 4.599 ± 1.004
3.833LeuArg: 3.833 ± 0.959
6.516LeuSer: 6.516 ± 1.204
8.816LeuThr: 8.816 ± 1.057
3.833LeuVal: 3.833 ± 1.353
1.533LeuTrp: 1.533 ± 0.657
3.833LeuTyr: 3.833 ± 1.169
0.0LeuXaa: 0.0 ± 0.0
Met
0.767MetAla: 0.767 ± 0.426
0.767MetCys: 0.767 ± 0.426
0.767MetAsp: 0.767 ± 0.419
0.767MetGlu: 0.767 ± 0.426
0.767MetPhe: 0.767 ± 0.45
0.767MetGly: 0.767 ± 0.501
0.767MetHis: 0.767 ± 0.52
0.0MetIle: 0.0 ± 0.0
0.767MetLys: 0.767 ± 0.956
0.767MetLeu: 0.767 ± 0.501
0.0MetMet: 0.0 ± 0.0
0.767MetAsn: 0.767 ± 0.501
1.15MetPro: 1.15 ± 1.019
1.15MetGln: 1.15 ± 0.638
1.15MetArg: 1.15 ± 0.55
1.533MetSer: 1.533 ± 0.688
2.683MetThr: 2.683 ± 1.038
1.15MetVal: 1.15 ± 0.55
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
6.516AsnAla: 6.516 ± 2.269
0.767AsnCys: 0.767 ± 0.45
2.683AsnAsp: 2.683 ± 0.913
3.066AsnGlu: 3.066 ± 0.969
1.533AsnPhe: 1.533 ± 1.319
1.916AsnGly: 1.916 ± 0.647
2.3AsnHis: 2.3 ± 2.033
2.3AsnIle: 2.3 ± 1.242
2.683AsnLys: 2.683 ± 0.802
4.216AsnLeu: 4.216 ± 1.036
0.767AsnMet: 0.767 ± 0.501
1.533AsnAsn: 1.533 ± 0.484
3.45AsnPro: 3.45 ± 1.649
2.683AsnGln: 2.683 ± 1.742
1.916AsnArg: 1.916 ± 0.68
2.683AsnSer: 2.683 ± 1.953
3.066AsnThr: 3.066 ± 1.002
3.45AsnVal: 3.45 ± 1.166
0.383AsnTrp: 0.383 ± 0.539
2.3AsnTyr: 2.3 ± 0.958
0.0AsnXaa: 0.0 ± 0.0
Pro
3.066ProAla: 3.066 ± 1.476
0.767ProCys: 0.767 ± 0.501
3.833ProAsp: 3.833 ± 1.236
3.45ProGlu: 3.45 ± 1.915
1.916ProPhe: 1.916 ± 1.149
3.066ProGly: 3.066 ± 1.337
2.3ProHis: 2.3 ± 0.552
2.3ProIle: 2.3 ± 0.456
2.683ProLys: 2.683 ± 1.007
4.983ProLeu: 4.983 ± 0.877
0.383ProMet: 0.383 ± 0.516
3.45ProAsn: 3.45 ± 0.391
4.983ProPro: 4.983 ± 2.529
1.533ProGln: 1.533 ± 0.666
3.066ProArg: 3.066 ± 0.91
6.133ProSer: 6.133 ± 0.818
6.133ProThr: 6.133 ± 1.615
2.683ProVal: 2.683 ± 0.932
0.0ProTrp: 0.0 ± 0.0
1.916ProTyr: 1.916 ± 1.048
0.0ProXaa: 0.0 ± 0.0
Gln
4.216GlnAla: 4.216 ± 1.123
0.0GlnCys: 0.0 ± 0.0
3.45GlnAsp: 3.45 ± 1.481
1.916GlnGlu: 1.916 ± 0.571
1.533GlnPhe: 1.533 ± 0.611
3.066GlnGly: 3.066 ± 2.138
0.383GlnHis: 0.383 ± 0.213
2.3GlnIle: 2.3 ± 0.566
1.15GlnLys: 1.15 ± 0.638
6.899GlnLeu: 6.899 ± 1.222
0.0GlnMet: 0.0 ± 0.0
2.683GlnAsn: 2.683 ± 1.828
2.683GlnPro: 2.683 ± 0.688
4.599GlnGln: 4.599 ± 1.613
2.683GlnArg: 2.683 ± 0.868
4.599GlnSer: 4.599 ± 1.32
3.066GlnThr: 3.066 ± 1.218
1.916GlnVal: 1.916 ± 0.474
0.767GlnTrp: 0.767 ± 0.426
0.767GlnTyr: 0.767 ± 0.554
0.0GlnXaa: 0.0 ± 0.0
Arg
5.749ArgAla: 5.749 ± 1.246
0.767ArgCys: 0.767 ± 0.908
3.066ArgAsp: 3.066 ± 0.821
3.833ArgGlu: 3.833 ± 0.861
2.3ArgPhe: 2.3 ± 0.999
0.767ArgGly: 0.767 ± 0.419
0.767ArgHis: 0.767 ± 0.426
2.683ArgIle: 2.683 ± 0.677
3.066ArgLys: 3.066 ± 1.767
6.516ArgLeu: 6.516 ± 1.383
0.0ArgMet: 0.0 ± 0.0
4.599ArgAsn: 4.599 ± 0.817
3.066ArgPro: 3.066 ± 0.742
3.066ArgGln: 3.066 ± 1.384
4.599ArgArg: 4.599 ± 1.678
2.3ArgSer: 2.3 ± 0.946
2.683ArgThr: 2.683 ± 1.56
1.533ArgVal: 1.533 ± 0.9
0.0ArgTrp: 0.0 ± 0.0
1.533ArgTyr: 1.533 ± 0.642
0.0ArgXaa: 0.0 ± 0.0
Ser
3.45SerAla: 3.45 ± 1.651
0.767SerCys: 0.767 ± 0.45
7.666SerAsp: 7.666 ± 1.954
4.983SerGlu: 4.983 ± 0.619
1.533SerPhe: 1.533 ± 0.819
2.3SerGly: 2.3 ± 0.781
1.533SerHis: 1.533 ± 0.484
3.066SerIle: 3.066 ± 1.002
5.366SerLys: 5.366 ± 2.779
5.749SerLeu: 5.749 ± 2.094
0.767SerMet: 0.767 ± 0.816
4.216SerAsn: 4.216 ± 1.78
2.683SerPro: 2.683 ± 0.902
4.216SerGln: 4.216 ± 0.896
3.45SerArg: 3.45 ± 0.805
6.516SerSer: 6.516 ± 1.452
5.749SerThr: 5.749 ± 2.395
4.216SerVal: 4.216 ± 0.88
0.767SerTrp: 0.767 ± 0.426
1.533SerTyr: 1.533 ± 0.515
0.0SerXaa: 0.0 ± 0.0
Thr
4.599ThrAla: 4.599 ± 1.672
0.383ThrCys: 0.383 ± 0.539
4.983ThrAsp: 4.983 ± 0.777
2.3ThrGlu: 2.3 ± 1.277
3.833ThrPhe: 3.833 ± 0.501
3.45ThrGly: 3.45 ± 0.627
4.216ThrHis: 4.216 ± 1.337
4.216ThrIle: 4.216 ± 1.429
4.216ThrLys: 4.216 ± 1.105
9.582ThrLeu: 9.582 ± 1.991
0.383ThrMet: 0.383 ± 0.213
5.749ThrAsn: 5.749 ± 0.685
4.983ThrPro: 4.983 ± 1.066
2.3ThrGln: 2.3 ± 0.999
3.45ThrArg: 3.45 ± 2.088
6.899ThrSer: 6.899 ± 1.065
6.516ThrThr: 6.516 ± 1.087
2.683ThrVal: 2.683 ± 0.74
0.0ThrTrp: 0.0 ± 0.0
1.533ThrTyr: 1.533 ± 0.484
0.0ThrXaa: 0.0 ± 0.0
Val
1.916ValAla: 1.916 ± 0.592
0.767ValCys: 0.767 ± 0.956
3.066ValAsp: 3.066 ± 1.218
2.3ValGlu: 2.3 ± 1.286
3.45ValPhe: 3.45 ± 1.062
1.916ValGly: 1.916 ± 1.103
0.767ValHis: 0.767 ± 0.426
3.45ValIle: 3.45 ± 1.166
4.599ValLys: 4.599 ± 0.712
4.216ValLeu: 4.216 ± 1.486
0.767ValMet: 0.767 ± 0.426
2.3ValAsn: 2.3 ± 0.614
4.216ValPro: 4.216 ± 2.427
1.533ValGln: 1.533 ± 0.598
3.066ValArg: 3.066 ± 1.029
2.3ValSer: 2.3 ± 0.555
3.833ValThr: 3.833 ± 0.793
1.533ValVal: 1.533 ± 0.9
0.383ValTrp: 0.383 ± 0.213
0.383ValTyr: 0.383 ± 0.213
0.0ValXaa: 0.0 ± 0.0
Trp
0.767TrpAla: 0.767 ± 0.501
0.0TrpCys: 0.0 ± 0.0
0.383TrpAsp: 0.383 ± 0.213
0.0TrpGlu: 0.0 ± 0.0
0.383TrpPhe: 0.383 ± 0.213
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.767TrpLys: 0.767 ± 0.426
0.767TrpLeu: 0.767 ± 0.419
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.767TrpPro: 0.767 ± 0.554
0.383TrpGln: 0.383 ± 0.516
0.383TrpArg: 0.383 ± 0.213
0.767TrpSer: 0.767 ± 0.501
0.383TrpThr: 0.383 ± 0.213
1.15TrpVal: 1.15 ± 0.638
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.833TyrAla: 3.833 ± 0.771
1.533TyrCys: 1.533 ± 0.666
1.916TyrAsp: 1.916 ± 0.628
1.533TyrGlu: 1.533 ± 1.187
0.383TyrPhe: 0.383 ± 0.213
3.45TyrGly: 3.45 ± 0.731
0.383TyrHis: 0.383 ± 0.539
0.767TyrIle: 0.767 ± 0.52
1.15TyrLys: 1.15 ± 0.418
3.066TyrLeu: 3.066 ± 1.702
0.383TyrMet: 0.383 ± 0.213
1.916TyrAsn: 1.916 ± 0.93
0.767TyrPro: 0.767 ± 0.426
1.15TyrGln: 1.15 ± 0.436
1.533TyrArg: 1.533 ± 0.727
1.15TyrSer: 1.15 ± 0.638
1.533TyrThr: 1.533 ± 0.517
1.533TyrVal: 1.533 ± 0.469
0.0TyrTrp: 0.0 ± 0.0
1.15TyrTyr: 1.15 ± 0.55
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2610 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski