Amino acid dipepetide frequency for Bean white chlorosis mosaic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.992AlaAla: 1.992 ± 1.043
0.664AlaCys: 0.664 ± 0.608
1.992AlaAsp: 1.992 ± 1.01
1.992AlaGlu: 1.992 ± 0.853
1.328AlaPhe: 1.328 ± 0.653
2.656AlaGly: 2.656 ± 1.174
0.664AlaHis: 0.664 ± 0.511
1.328AlaIle: 1.328 ± 0.79
3.32AlaLys: 3.32 ± 1.243
4.648AlaLeu: 4.648 ± 1.536
0.664AlaMet: 0.664 ± 0.608
2.656AlaAsn: 2.656 ± 1.07
2.656AlaPro: 2.656 ± 1.168
3.32AlaGln: 3.32 ± 1.199
3.984AlaArg: 3.984 ± 1.364
7.968AlaSer: 7.968 ± 3.009
3.984AlaThr: 3.984 ± 1.161
1.328AlaVal: 1.328 ± 0.796
0.0AlaTrp: 0.0 ± 0.0
1.328AlaTyr: 1.328 ± 0.868
0.0AlaXaa: 0.0 ± 0.0
Cys
0.664CysAla: 0.664 ± 0.576
0.0CysCys: 0.0 ± 0.0
0.664CysAsp: 0.664 ± 0.576
0.664CysGlu: 0.664 ± 0.608
0.0CysPhe: 0.0 ± 0.0
0.664CysGly: 0.664 ± 0.752
0.0CysHis: 0.0 ± 0.0
1.328CysIle: 1.328 ± 0.753
2.656CysLys: 2.656 ± 0.592
0.664CysLeu: 0.664 ± 0.614
0.664CysMet: 0.664 ± 0.576
1.328CysAsn: 1.328 ± 0.669
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.664CysArg: 0.664 ± 0.511
1.992CysSer: 1.992 ± 1.14
2.656CysThr: 2.656 ± 1.473
1.328CysVal: 1.328 ± 0.753
0.664CysTrp: 0.664 ± 0.614
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
0.664AspAla: 0.664 ± 0.576
0.0AspCys: 0.0 ± 0.0
1.992AspAsp: 1.992 ± 1.106
3.984AspGlu: 3.984 ± 1.081
2.656AspPhe: 2.656 ± 0.974
3.32AspGly: 3.32 ± 1.772
1.992AspHis: 1.992 ± 0.842
2.656AspIle: 2.656 ± 1.502
1.992AspLys: 1.992 ± 1.139
7.304AspLeu: 7.304 ± 1.45
0.664AspMet: 0.664 ± 0.614
1.992AspAsn: 1.992 ± 0.735
1.992AspPro: 1.992 ± 1.284
0.0AspGln: 0.0 ± 0.0
4.648AspArg: 4.648 ± 1.947
6.64AspSer: 6.64 ± 1.596
3.32AspThr: 3.32 ± 1.246
3.984AspVal: 3.984 ± 1.077
0.0AspTrp: 0.0 ± 0.0
1.992AspTyr: 1.992 ± 0.65
0.0AspXaa: 0.0 ± 0.0
Glu
2.656GluAla: 2.656 ± 1.07
1.328GluCys: 1.328 ± 0.827
1.992GluAsp: 1.992 ± 1.423
3.984GluGlu: 3.984 ± 2.422
1.328GluPhe: 1.328 ± 0.72
3.984GluGly: 3.984 ± 1.644
0.664GluHis: 0.664 ± 0.752
3.32GluIle: 3.32 ± 2.057
0.664GluLys: 0.664 ± 0.614
3.984GluLeu: 3.984 ± 1.196
1.328GluMet: 1.328 ± 0.776
5.976GluAsn: 5.976 ± 1.662
2.656GluPro: 2.656 ± 1.212
2.656GluGln: 2.656 ± 1.134
1.992GluArg: 1.992 ± 0.65
3.984GluSer: 3.984 ± 2.789
0.664GluThr: 0.664 ± 0.511
2.656GluVal: 2.656 ± 1.166
2.656GluTrp: 2.656 ± 1.07
1.992GluTyr: 1.992 ± 1.139
0.0GluXaa: 0.0 ± 0.0
Phe
1.328PheAla: 1.328 ± 0.865
0.664PheCys: 0.664 ± 0.608
2.656PheAsp: 2.656 ± 1.212
1.328PheGlu: 1.328 ± 0.796
1.992PhePhe: 1.992 ± 1.043
1.992PheGly: 1.992 ± 0.761
1.992PheHis: 1.992 ± 1.106
1.992PheIle: 1.992 ± 1.087
4.648PheLys: 4.648 ± 2.446
1.992PheLeu: 1.992 ± 1.533
0.0PheMet: 0.0 ± 0.0
3.984PheAsn: 3.984 ± 0.893
1.992PhePro: 1.992 ± 1.139
2.656PheGln: 2.656 ± 1.252
1.328PheArg: 1.328 ± 0.669
2.656PheSer: 2.656 ± 1.585
3.32PheThr: 3.32 ± 0.869
1.328PheVal: 1.328 ± 1.228
2.656PheTrp: 2.656 ± 1.261
1.992PheTyr: 1.992 ± 1.269
0.0PheXaa: 0.0 ± 0.0
Gly
2.656GlyAla: 2.656 ± 0.971
2.656GlyCys: 2.656 ± 1.605
2.656GlyAsp: 2.656 ± 1.261
3.32GlyGlu: 3.32 ± 1.241
1.328GlyPhe: 1.328 ± 0.928
5.312GlyGly: 5.312 ± 1.823
1.328GlyHis: 1.328 ± 0.796
1.992GlyIle: 1.992 ± 1.02
8.632GlyLys: 8.632 ± 2.834
0.664GlyLeu: 0.664 ± 0.576
0.0GlyMet: 0.0 ± 0.565
2.656GlyAsn: 2.656 ± 1.445
3.984GlyPro: 3.984 ± 0.938
5.976GlyGln: 5.976 ± 1.773
1.992GlyArg: 1.992 ± 0.779
4.648GlySer: 4.648 ± 0.911
3.984GlyThr: 3.984 ± 1.323
2.656GlyVal: 2.656 ± 1.736
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.664HisAla: 0.664 ± 0.608
1.328HisCys: 1.328 ± 0.827
3.32HisAsp: 3.32 ± 1.251
1.992HisGlu: 1.992 ± 0.899
1.992HisPhe: 1.992 ± 1.043
1.328HisGly: 1.328 ± 0.928
1.328HisHis: 1.328 ± 0.796
1.328HisIle: 1.328 ± 1.237
1.328HisLys: 1.328 ± 0.841
2.656HisLeu: 2.656 ± 0.971
1.992HisMet: 1.992 ± 1.124
2.656HisAsn: 2.656 ± 1.132
1.328HisPro: 1.328 ± 0.669
1.992HisGln: 1.992 ± 0.92
2.656HisArg: 2.656 ± 1.502
1.992HisSer: 1.992 ± 0.842
1.992HisThr: 1.992 ± 1.269
3.32HisVal: 3.32 ± 1.008
0.664HisTrp: 0.664 ± 0.511
1.328HisTyr: 1.328 ± 0.669
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
0.664IleCys: 0.664 ± 0.511
3.984IleAsp: 3.984 ± 1.539
3.32IleGlu: 3.32 ± 1.615
0.664IlePhe: 0.664 ± 0.511
2.656IleGly: 2.656 ± 1.449
1.992IleHis: 1.992 ± 1.13
1.328IleIle: 1.328 ± 0.669
4.648IleLys: 4.648 ± 1.335
1.992IleLeu: 1.992 ± 1.195
0.664IleMet: 0.664 ± 0.608
1.992IleAsn: 1.992 ± 1.284
3.32IlePro: 3.32 ± 0.924
3.984IleGln: 3.984 ± 1.911
5.976IleArg: 5.976 ± 1.727
5.312IleSer: 5.312 ± 2.235
3.984IleThr: 3.984 ± 0.826
3.32IleVal: 3.32 ± 1.233
1.992IleTrp: 1.992 ± 1.193
3.984IleTyr: 3.984 ± 2.05
0.0IleXaa: 0.0 ± 0.0
Lys
3.32LysAla: 3.32 ± 1.317
0.0LysCys: 0.0 ± 0.0
4.648LysAsp: 4.648 ± 1.666
3.32LysGlu: 3.32 ± 1.953
3.32LysPhe: 3.32 ± 0.959
2.656LysGly: 2.656 ± 1.074
1.992LysHis: 1.992 ± 0.779
4.648LysIle: 4.648 ± 1.013
3.984LysLys: 3.984 ± 2.387
5.312LysLeu: 5.312 ± 1.377
0.664LysMet: 0.664 ± 0.614
3.32LysAsn: 3.32 ± 1.291
3.984LysPro: 3.984 ± 1.081
0.664LysGln: 0.664 ± 0.576
7.968LysArg: 7.968 ± 2.924
3.984LysSer: 3.984 ± 1.273
1.328LysThr: 1.328 ± 0.72
4.648LysVal: 4.648 ± 2.919
0.664LysTrp: 0.664 ± 0.511
1.992LysTyr: 1.992 ± 1.02
0.0LysXaa: 0.0 ± 0.0
Leu
0.664LeuAla: 0.664 ± 0.511
0.664LeuCys: 0.664 ± 0.511
5.312LeuAsp: 5.312 ± 1.53
1.328LeuGlu: 1.328 ± 1.237
3.32LeuPhe: 3.32 ± 1.639
4.648LeuGly: 4.648 ± 0.911
3.32LeuHis: 3.32 ± 0.869
2.656LeuIle: 2.656 ± 1.256
7.304LeuLys: 7.304 ± 1.37
3.32LeuLeu: 3.32 ± 2.003
0.664LeuMet: 0.664 ± 0.614
4.648LeuAsn: 4.648 ± 2.205
1.992LeuPro: 1.992 ± 1.576
3.32LeuGln: 3.32 ± 1.777
3.984LeuArg: 3.984 ± 1.343
8.632LeuSer: 8.632 ± 2.425
3.984LeuThr: 3.984 ± 1.49
5.312LeuVal: 5.312 ± 0.886
0.664LeuTrp: 0.664 ± 0.614
3.32LeuTyr: 3.32 ± 1.316
0.0LeuXaa: 0.0 ± 0.0
Met
0.664MetAla: 0.664 ± 0.608
1.328MetCys: 1.328 ± 1.009
3.32MetAsp: 3.32 ± 1.155
0.0MetGlu: 0.0 ± 0.0
1.328MetPhe: 1.328 ± 1.216
1.328MetGly: 1.328 ± 1.096
0.664MetHis: 0.664 ± 0.608
0.0MetIle: 0.0 ± 0.0
1.328MetLys: 1.328 ± 0.753
0.664MetLeu: 0.664 ± 0.912
0.0MetMet: 0.0 ± 0.0
1.328MetAsn: 1.328 ± 0.79
1.992MetPro: 1.992 ± 1.168
0.664MetGln: 0.664 ± 0.511
0.664MetArg: 0.664 ± 0.752
3.32MetSer: 3.32 ± 1.74
1.328MetThr: 1.328 ± 0.653
0.664MetVal: 0.664 ± 0.614
0.664MetTrp: 0.664 ± 0.511
1.992MetTyr: 1.992 ± 0.91
0.0MetXaa: 0.0 ± 0.0
Asn
5.976AsnAla: 5.976 ± 1.343
1.328AsnCys: 1.328 ± 0.669
1.992AsnAsp: 1.992 ± 0.761
3.32AsnGlu: 3.32 ± 1.913
0.664AsnPhe: 0.664 ± 0.714
1.992AsnGly: 1.992 ± 1.193
3.32AsnHis: 3.32 ± 2.395
3.32AsnIle: 3.32 ± 0.885
1.992AsnLys: 1.992 ± 1.087
4.648AsnLeu: 4.648 ± 1.978
1.992AsnMet: 1.992 ± 1.222
1.992AsnAsn: 1.992 ± 0.802
3.984AsnPro: 3.984 ± 0.893
1.328AsnGln: 1.328 ± 1.054
3.984AsnArg: 3.984 ± 1.706
2.656AsnSer: 2.656 ± 0.592
3.32AsnThr: 3.32 ± 1.338
2.656AsnVal: 2.656 ± 1.108
0.664AsnTrp: 0.664 ± 0.511
3.32AsnTyr: 3.32 ± 0.959
0.0AsnXaa: 0.0 ± 0.0
Pro
0.664ProAla: 0.664 ± 0.511
0.664ProCys: 0.664 ± 0.608
1.992ProAsp: 1.992 ± 0.861
2.656ProGlu: 2.656 ± 1.131
1.328ProPhe: 1.328 ± 0.669
3.32ProGly: 3.32 ± 1.282
3.32ProHis: 3.32 ± 2.019
3.32ProIle: 3.32 ± 2.878
3.32ProLys: 3.32 ± 0.978
4.648ProLeu: 4.648 ± 1.853
1.328ProMet: 1.328 ± 1.216
2.656ProAsn: 2.656 ± 1.074
3.984ProPro: 3.984 ± 1.874
4.648ProGln: 4.648 ± 2.497
3.32ProArg: 3.32 ± 2.025
5.312ProSer: 5.312 ± 2.029
3.984ProThr: 3.984 ± 1.838
1.992ProVal: 1.992 ± 1.02
1.992ProTrp: 1.992 ± 0.705
1.328ProTyr: 1.328 ± 0.753
0.0ProXaa: 0.0 ± 0.0
Gln
2.656GlnAla: 2.656 ± 1.253
1.328GlnCys: 1.328 ± 1.022
0.664GlnAsp: 0.664 ± 0.752
3.984GlnGlu: 3.984 ± 1.273
2.656GlnPhe: 2.656 ± 1.339
1.992GlnGly: 1.992 ± 1.106
2.656GlnHis: 2.656 ± 1.166
2.656GlnIle: 2.656 ± 1.564
1.328GlnLys: 1.328 ± 1.022
3.32GlnLeu: 3.32 ± 2.508
0.664GlnMet: 0.664 ± 0.521
0.664GlnAsn: 0.664 ± 0.511
3.984GlnPro: 3.984 ± 1.639
1.328GlnGln: 1.328 ± 0.669
3.32GlnArg: 3.32 ± 1.05
4.648GlnSer: 4.648 ± 1.074
1.328GlnThr: 1.328 ± 0.796
2.656GlnVal: 2.656 ± 1.272
0.0GlnTrp: 0.0 ± 0.0
1.328GlnTyr: 1.328 ± 0.79
0.0GlnXaa: 0.0 ± 0.0
Arg
5.976ArgAla: 5.976 ± 1.705
1.328ArgCys: 1.328 ± 1.151
2.656ArgAsp: 2.656 ± 1.805
1.992ArgGlu: 1.992 ± 1.14
5.976ArgPhe: 5.976 ± 2.368
5.312ArgGly: 5.312 ± 1.526
2.656ArgHis: 2.656 ± 1.126
5.312ArgIle: 5.312 ± 1.5
2.656ArgLys: 2.656 ± 1.044
3.32ArgLeu: 3.32 ± 1.593
1.328ArgMet: 1.328 ± 1.03
2.656ArgAsn: 2.656 ± 1.212
3.32ArgPro: 3.32 ± 1.245
0.664ArgGln: 0.664 ± 0.576
4.648ArgArg: 4.648 ± 2.745
7.304ArgSer: 7.304 ± 1.551
5.312ArgThr: 5.312 ± 2.001
4.648ArgVal: 4.648 ± 0.754
0.664ArgTrp: 0.664 ± 0.576
1.328ArgTyr: 1.328 ± 0.79
0.0ArgXaa: 0.0 ± 0.0
Ser
5.312SerAla: 5.312 ± 1.816
1.328SerCys: 1.328 ± 0.653
3.984SerAsp: 3.984 ± 1.081
1.328SerGlu: 1.328 ± 0.753
2.656SerPhe: 2.656 ± 0.708
1.992SerGly: 1.992 ± 1.056
3.984SerHis: 3.984 ± 1.588
7.968SerIle: 7.968 ± 2.931
4.648SerLys: 4.648 ± 1.23
7.968SerLeu: 7.968 ± 1.667
1.328SerMet: 1.328 ± 1.151
4.648SerAsn: 4.648 ± 1.211
5.976SerPro: 5.976 ± 2.693
2.656SerGln: 2.656 ± 1.339
7.304SerArg: 7.304 ± 1.732
7.304SerSer: 7.304 ± 5.44
8.632SerThr: 8.632 ± 3.018
4.648SerVal: 4.648 ± 1.307
1.328SerTrp: 1.328 ± 1.151
3.32SerTyr: 3.32 ± 0.991
0.0SerXaa: 0.0 ± 0.0
Thr
6.64ThrAla: 6.64 ± 2.094
0.0ThrCys: 0.0 ± 0.0
2.656ThrAsp: 2.656 ± 1.621
2.656ThrGlu: 2.656 ± 1.064
3.32ThrPhe: 3.32 ± 2.289
5.312ThrGly: 5.312 ± 0.649
3.984ThrHis: 3.984 ± 1.964
1.992ThrIle: 1.992 ± 1.1
0.664ThrLys: 0.664 ± 0.511
4.648ThrLeu: 4.648 ± 1.477
1.992ThrMet: 1.992 ± 0.65
3.32ThrAsn: 3.32 ± 0.959
4.648ThrPro: 4.648 ± 1.495
0.664ThrGln: 0.664 ± 0.511
3.32ThrArg: 3.32 ± 1.104
3.32ThrSer: 3.32 ± 2.863
3.32ThrThr: 3.32 ± 1.226
4.648ThrVal: 4.648 ± 1.208
0.0ThrTrp: 0.0 ± 0.0
3.32ThrTyr: 3.32 ± 1.218
0.0ThrXaa: 0.0 ± 0.0
Val
1.328ValAla: 1.328 ± 1.022
0.664ValCys: 0.664 ± 0.576
3.984ValAsp: 3.984 ± 1.6
6.64ValGlu: 6.64 ± 1.862
2.656ValPhe: 2.656 ± 1.212
2.656ValGly: 2.656 ± 1.507
1.328ValHis: 1.328 ± 0.865
3.984ValIle: 3.984 ± 1.706
3.984ValLys: 3.984 ± 1.556
2.656ValLeu: 2.656 ± 0.971
2.656ValMet: 2.656 ± 1.826
3.32ValAsn: 3.32 ± 1.105
1.992ValPro: 1.992 ± 0.705
3.32ValGln: 3.32 ± 0.894
2.656ValArg: 2.656 ± 1.096
3.32ValSer: 3.32 ± 1.004
1.328ValThr: 1.328 ± 1.216
3.984ValVal: 3.984 ± 1.706
0.664ValTrp: 0.664 ± 0.714
5.312ValTyr: 5.312 ± 1.802
0.0ValXaa: 0.0 ± 0.0
Trp
2.656TrpAla: 2.656 ± 1.5
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.328TrpGlu: 1.328 ± 0.865
0.0TrpPhe: 0.0 ± 0.0
0.664TrpGly: 0.664 ± 0.511
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.992TrpLys: 1.992 ± 0.705
0.664TrpLeu: 0.664 ± 0.608
1.328TrpMet: 1.328 ± 0.79
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.664TrpGln: 0.664 ± 0.511
1.328TrpArg: 1.328 ± 0.928
1.328TrpSer: 1.328 ± 1.054
2.656TrpThr: 2.656 ± 1.108
1.328TrpVal: 1.328 ± 0.928
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.992TyrAla: 1.992 ± 1.168
0.664TyrCys: 0.664 ± 0.614
1.328TyrAsp: 1.328 ± 0.79
1.328TyrGlu: 1.328 ± 1.216
3.984TyrPhe: 3.984 ± 0.959
3.32TyrGly: 3.32 ± 1.008
0.0TyrHis: 0.0 ± 0.0
4.648TyrIle: 4.648 ± 1.423
1.328TyrLys: 1.328 ± 0.796
3.984TyrLeu: 3.984 ± 2.305
2.656TyrMet: 2.656 ± 1.484
2.656TyrAsn: 2.656 ± 1.212
1.992TyrPro: 1.992 ± 1.237
2.656TyrGln: 2.656 ± 0.974
3.32TyrArg: 3.32 ± 1.929
1.992TyrSer: 1.992 ± 0.802
0.0TyrThr: 0.0 ± 0.0
1.328TyrVal: 1.328 ± 1.428
0.0TyrTrp: 0.0 ± 0.0
1.328TyrTyr: 1.328 ± 0.653
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1507 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski