Amino acid dipepetide frequency for Pythium polare bunya-like RNA virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.399AlaAla: 0.399 ± 0.197
0.399AlaCys: 0.399 ± 0.197
1.196AlaAsp: 1.196 ± 0.592
1.594AlaGlu: 1.594 ± 0.755
1.993AlaPhe: 1.993 ± 0.558
1.993AlaGly: 1.993 ± 0.987
0.797AlaHis: 0.797 ± 0.395
1.196AlaIle: 1.196 ± 0.592
1.594AlaLys: 1.594 ± 0.789
3.587AlaLeu: 3.587 ± 1.313
1.196AlaMet: 1.196 ± 0.953
1.594AlaAsn: 1.594 ± 3.844
1.196AlaPro: 1.196 ± 0.953
0.797AlaGln: 0.797 ± 0.395
0.399AlaArg: 0.399 ± 0.197
1.993AlaSer: 1.993 ± 0.987
0.399AlaThr: 0.399 ± 0.197
1.594AlaVal: 1.594 ± 2.3
0.0AlaTrp: 0.0 ± 0.0
1.594AlaTyr: 1.594 ± 0.789
0.0AlaXaa: 0.0 ± 0.0
Cys
1.594CysAla: 1.594 ± 0.755
0.399CysCys: 0.399 ± 1.347
0.797CysAsp: 0.797 ± 0.395
0.399CysGlu: 0.399 ± 0.197
0.399CysPhe: 0.399 ± 1.347
0.399CysGly: 0.399 ± 0.197
0.0CysHis: 0.0 ± 0.0
1.196CysIle: 1.196 ± 0.953
1.594CysLys: 1.594 ± 0.789
3.189CysLeu: 3.189 ± 1.578
0.797CysMet: 0.797 ± 0.395
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.399CysGln: 0.399 ± 0.197
0.797CysArg: 0.797 ± 0.395
1.196CysSer: 1.196 ± 0.953
0.399CysThr: 0.399 ± 0.197
0.399CysVal: 0.399 ± 0.197
0.399CysTrp: 0.399 ± 1.347
0.399CysTyr: 0.399 ± 0.197
0.0CysXaa: 0.0 ± 0.0
Asp
0.399AspAla: 0.399 ± 1.347
1.196AspCys: 1.196 ± 0.953
4.783AspAsp: 4.783 ± 0.721
4.384AspGlu: 4.384 ± 5.552
6.776AspPhe: 6.776 ± 0.265
1.196AspGly: 1.196 ± 0.592
0.399AspHis: 0.399 ± 0.197
7.174AspIle: 7.174 ± 1.082
4.783AspLys: 4.783 ± 0.823
5.978AspLeu: 5.978 ± 1.415
4.783AspMet: 4.783 ± 6.022
2.79AspAsn: 2.79 ± 1.381
2.391AspPro: 2.391 ± 1.184
0.797AspGln: 0.797 ± 0.395
1.594AspArg: 1.594 ± 0.755
5.58AspSer: 5.58 ± 0.327
3.986AspThr: 3.986 ± 1.973
3.587AspVal: 3.587 ± 1.313
0.0AspTrp: 0.0 ± 0.0
7.573AspTyr: 7.573 ± 0.66
0.0AspXaa: 0.0 ± 0.0
Glu
1.594GluAla: 1.594 ± 0.755
0.399GluCys: 0.399 ± 0.197
4.783GluAsp: 4.783 ± 2.266
2.391GluGlu: 2.391 ± 1.905
1.594GluPhe: 1.594 ± 0.789
1.993GluGly: 1.993 ± 0.558
1.196GluHis: 1.196 ± 0.592
3.189GluIle: 3.189 ± 1.578
7.971GluLys: 7.971 ± 3.777
7.573GluLeu: 7.573 ± 0.885
2.391GluMet: 2.391 ± 0.361
4.783GluAsn: 4.783 ± 0.823
1.196GluPro: 1.196 ± 0.592
0.797GluGln: 0.797 ± 0.395
2.79GluArg: 2.79 ± 1.708
4.384GluSer: 4.384 ± 2.17
1.993GluThr: 1.993 ± 0.558
3.587GluVal: 3.587 ± 2.858
0.399GluTrp: 0.399 ± 1.347
2.79GluTyr: 2.79 ± 0.163
0.0GluXaa: 0.0 ± 0.0
Phe
1.196PheAla: 1.196 ± 0.592
0.797PheCys: 0.797 ± 0.395
6.377PheAsp: 6.377 ± 1.477
5.181PheGlu: 5.181 ± 1.02
1.993PhePhe: 1.993 ± 0.987
1.993PheGly: 1.993 ± 2.103
0.0PheHis: 0.0 ± 0.0
4.783PheIle: 4.783 ± 2.368
4.384PheLys: 4.384 ± 0.626
5.181PheLeu: 5.181 ± 3.613
1.196PheMet: 1.196 ± 0.592
6.776PheAsn: 6.776 ± 0.265
1.993PhePro: 1.993 ± 2.103
1.196PheGln: 1.196 ± 2.497
0.797PheArg: 0.797 ± 0.395
5.978PheSer: 5.978 ± 1.415
1.993PheThr: 1.993 ± 0.987
3.189PheVal: 3.189 ± 1.511
1.196PheTrp: 1.196 ± 0.592
3.587PheTyr: 3.587 ± 0.231
0.0PheXaa: 0.0 ± 0.0
Gly
0.399GlyAla: 0.399 ± 0.197
0.0GlyCys: 0.0 ± 0.0
3.986GlyAsp: 3.986 ± 2.661
2.79GlyGlu: 2.79 ± 1.708
1.993GlyPhe: 1.993 ± 0.558
2.79GlyGly: 2.79 ± 1.708
0.399GlyHis: 0.399 ± 0.197
3.587GlyIle: 3.587 ± 1.313
1.993GlyLys: 1.993 ± 0.987
4.783GlyLeu: 4.783 ± 2.368
1.594GlyMet: 1.594 ± 0.755
2.79GlyAsn: 2.79 ± 1.708
0.0GlyPro: 0.0 ± 0.0
0.797GlyGln: 0.797 ± 1.15
1.196GlyArg: 1.196 ± 0.953
3.986GlySer: 3.986 ± 0.428
1.594GlyThr: 1.594 ± 0.789
3.189GlyVal: 3.189 ± 0.034
0.399GlyTrp: 0.399 ± 0.197
1.594GlyTyr: 1.594 ± 0.789
0.0GlyXaa: 0.0 ± 0.0
His
1.594HisAla: 1.594 ± 0.755
0.0HisCys: 0.0 ± 0.0
0.399HisAsp: 0.399 ± 0.197
1.594HisGlu: 1.594 ± 0.789
1.993HisPhe: 1.993 ± 0.987
0.399HisGly: 0.399 ± 0.197
0.797HisHis: 0.797 ± 0.395
1.594HisIle: 1.594 ± 0.789
3.189HisLys: 3.189 ± 1.578
3.587HisLeu: 3.587 ± 0.231
0.399HisMet: 0.399 ± 1.347
1.993HisAsn: 1.993 ± 0.987
0.399HisPro: 0.399 ± 0.197
0.399HisGln: 0.399 ± 0.197
0.0HisArg: 0.0 ± 0.0
1.993HisSer: 1.993 ± 0.987
0.797HisThr: 0.797 ± 0.395
0.399HisVal: 0.399 ± 0.197
0.0HisTrp: 0.0 ± 0.0
0.399HisTyr: 0.399 ± 1.347
0.0HisXaa: 0.0 ± 0.0
Ile
1.594IleAla: 1.594 ± 0.789
0.797IleCys: 0.797 ± 1.15
3.587IleAsp: 3.587 ± 0.231
3.587IleGlu: 3.587 ± 0.231
5.181IlePhe: 5.181 ± 2.069
3.189IleGly: 3.189 ± 1.511
1.594IleHis: 1.594 ± 0.789
2.391IleIle: 2.391 ± 0.361
6.776IleLys: 6.776 ± 1.28
4.783IleLeu: 4.783 ± 0.721
3.189IleMet: 3.189 ± 0.034
4.384IleAsn: 4.384 ± 2.17
2.391IlePro: 2.391 ± 0.361
1.594IleGln: 1.594 ± 0.755
3.587IleArg: 3.587 ± 1.776
8.768IleSer: 8.768 ± 4.341
3.587IleThr: 3.587 ± 1.313
3.189IleVal: 3.189 ± 1.578
0.0IleTrp: 0.0 ± 0.0
5.181IleTyr: 5.181 ± 1.02
0.0IleXaa: 0.0 ± 0.0
Lys
1.993LysAla: 1.993 ± 3.647
1.993LysCys: 1.993 ± 0.987
5.181LysAsp: 5.181 ± 2.069
4.783LysGlu: 4.783 ± 2.266
5.978LysPhe: 5.978 ± 0.13
3.986LysGly: 3.986 ± 1.973
2.79LysHis: 2.79 ± 1.381
6.377LysIle: 6.377 ± 0.068
5.978LysLys: 5.978 ± 0.13
5.58LysLeu: 5.58 ± 0.327
2.391LysMet: 2.391 ± 0.361
6.377LysAsn: 6.377 ± 3.157
1.993LysPro: 1.993 ± 0.558
1.196LysGln: 1.196 ± 0.592
5.181LysArg: 5.181 ± 1.02
8.768LysSer: 8.768 ± 0.293
2.79LysThr: 2.79 ± 0.163
6.776LysVal: 6.776 ± 1.81
1.196LysTrp: 1.196 ± 0.592
4.783LysTyr: 4.783 ± 0.823
0.0LysXaa: 0.0 ± 0.0
Leu
5.978LeuAla: 5.978 ± 2.96
2.391LeuCys: 2.391 ± 0.361
7.174LeuAsp: 7.174 ± 2.627
6.377LeuGlu: 6.377 ± 3.157
3.587LeuPhe: 3.587 ± 1.776
4.783LeuGly: 4.783 ± 0.823
1.594LeuHis: 1.594 ± 0.789
8.768LeuIle: 8.768 ± 4.341
11.957LeuLys: 11.957 ± 1.804
9.167LeuLeu: 9.167 ± 0.096
3.986LeuMet: 3.986 ± 0.347
8.768LeuAsn: 8.768 ± 0.293
4.384LeuPro: 4.384 ± 0.919
2.79LeuGln: 2.79 ± 0.163
5.181LeuArg: 5.181 ± 0.524
11.16LeuSer: 11.16 ± 0.891
3.986LeuThr: 3.986 ± 2.661
3.189LeuVal: 3.189 ± 0.034
0.797LeuTrp: 0.797 ± 0.395
4.384LeuTyr: 4.384 ± 0.626
0.0LeuXaa: 0.0 ± 0.0
Met
0.797MetAla: 0.797 ± 0.395
0.399MetCys: 0.399 ± 0.197
1.196MetAsp: 1.196 ± 0.953
0.797MetGlu: 0.797 ± 1.15
1.993MetPhe: 1.993 ± 2.103
1.594MetGly: 1.594 ± 0.755
1.594MetHis: 1.594 ± 0.789
3.189MetIle: 3.189 ± 3.055
1.594MetLys: 1.594 ± 0.789
4.783MetLeu: 4.783 ± 0.823
1.196MetMet: 1.196 ± 0.592
1.993MetAsn: 1.993 ± 0.558
2.391MetPro: 2.391 ± 0.361
1.594MetGln: 1.594 ± 2.3
0.797MetArg: 0.797 ± 0.395
3.587MetSer: 3.587 ± 1.776
1.993MetThr: 1.993 ± 0.558
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
2.391MetTyr: 2.391 ± 0.361
0.0MetXaa: 0.0 ± 0.0
Asn
0.399AsnAla: 0.399 ± 0.197
0.797AsnCys: 0.797 ± 0.395
4.783AsnAsp: 4.783 ± 0.721
2.79AsnGlu: 2.79 ± 1.381
6.377AsnPhe: 6.377 ± 3.021
2.391AsnGly: 2.391 ± 0.361
0.797AsnHis: 0.797 ± 0.395
5.978AsnIle: 5.978 ± 1.415
5.978AsnLys: 5.978 ± 1.415
9.964AsnLeu: 9.964 ± 0.299
1.594AsnMet: 1.594 ± 0.755
3.587AsnAsn: 3.587 ± 1.776
3.189AsnPro: 3.189 ± 3.055
1.196AsnGln: 1.196 ± 0.592
1.993AsnArg: 1.993 ± 0.558
5.181AsnSer: 5.181 ± 0.524
2.391AsnThr: 2.391 ± 1.184
5.978AsnVal: 5.978 ± 2.96
0.0AsnTrp: 0.0 ± 0.0
2.391AsnTyr: 2.391 ± 0.361
0.0AsnXaa: 0.0 ± 0.0
Pro
0.797ProAla: 0.797 ± 0.395
0.797ProCys: 0.797 ± 0.395
1.594ProAsp: 1.594 ± 0.789
0.797ProGlu: 0.797 ± 0.395
1.993ProPhe: 1.993 ± 0.987
1.196ProGly: 1.196 ± 2.497
0.399ProHis: 0.399 ± 1.347
2.79ProIle: 2.79 ± 0.163
2.79ProLys: 2.79 ± 1.708
1.993ProLeu: 1.993 ± 0.987
0.797ProMet: 0.797 ± 0.395
2.79ProAsn: 2.79 ± 0.163
0.399ProPro: 0.399 ± 1.347
1.594ProGln: 1.594 ± 0.755
1.993ProArg: 1.993 ± 0.558
1.594ProSer: 1.594 ± 0.789
0.0ProThr: 0.0 ± 0.0
1.993ProVal: 1.993 ± 2.103
0.797ProTrp: 0.797 ± 1.15
1.196ProTyr: 1.196 ± 0.592
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
0.399GlnCys: 0.399 ± 0.197
2.79GlnAsp: 2.79 ± 0.163
1.594GlnGlu: 1.594 ± 2.3
1.196GlnPhe: 1.196 ± 0.592
0.797GlnGly: 0.797 ± 2.694
0.797GlnHis: 0.797 ± 1.15
1.196GlnIle: 1.196 ± 0.953
2.391GlnLys: 2.391 ± 1.184
1.196GlnLeu: 1.196 ± 0.592
0.797GlnMet: 0.797 ± 0.395
1.196GlnAsn: 1.196 ± 0.592
0.0GlnPro: 0.0 ± 0.0
1.594GlnGln: 1.594 ± 0.789
1.594GlnArg: 1.594 ± 0.789
1.594GlnSer: 1.594 ± 0.755
0.399GlnThr: 0.399 ± 0.197
0.797GlnVal: 0.797 ± 0.395
0.0GlnTrp: 0.0 ± 0.0
1.594GlnTyr: 1.594 ± 0.789
0.0GlnXaa: 0.0 ± 0.0
Arg
1.993ArgAla: 1.993 ± 2.103
0.797ArgCys: 0.797 ± 1.15
4.384ArgAsp: 4.384 ± 0.626
2.79ArgGlu: 2.79 ± 1.708
3.189ArgPhe: 3.189 ± 0.034
3.189ArgGly: 3.189 ± 0.034
1.196ArgHis: 1.196 ± 0.592
2.391ArgIle: 2.391 ± 1.184
3.189ArgLys: 3.189 ± 0.034
4.384ArgLeu: 4.384 ± 0.626
0.399ArgMet: 0.399 ± 0.197
3.189ArgAsn: 3.189 ± 0.034
1.196ArgPro: 1.196 ± 0.592
0.0ArgGln: 0.0 ± 0.0
0.797ArgArg: 0.797 ± 1.15
4.384ArgSer: 4.384 ± 0.626
1.594ArgThr: 1.594 ± 0.789
1.196ArgVal: 1.196 ± 0.592
0.399ArgTrp: 0.399 ± 0.197
2.391ArgTyr: 2.391 ± 1.184
0.0ArgXaa: 0.0 ± 0.0
Ser
1.594SerAla: 1.594 ± 0.789
0.797SerCys: 0.797 ± 0.395
7.971SerAsp: 7.971 ± 0.857
5.978SerGlu: 5.978 ± 2.96
6.776SerPhe: 6.776 ± 1.81
2.79SerGly: 2.79 ± 1.381
2.391SerHis: 2.391 ± 0.361
6.377SerIle: 6.377 ± 1.477
8.768SerLys: 8.768 ± 2.796
7.573SerLeu: 7.573 ± 0.66
2.391SerMet: 2.391 ± 1.184
7.573SerAsn: 7.573 ± 0.66
0.797SerPro: 0.797 ± 0.395
1.594SerGln: 1.594 ± 0.789
4.783SerArg: 4.783 ± 0.721
8.37SerSer: 8.37 ± 2.599
3.986SerThr: 3.986 ± 1.973
3.189SerVal: 3.189 ± 1.578
1.196SerTrp: 1.196 ± 0.953
6.776SerTyr: 6.776 ± 1.28
0.0SerXaa: 0.0 ± 0.0
Thr
1.993ThrAla: 1.993 ± 2.103
0.399ThrCys: 0.399 ± 0.197
0.797ThrAsp: 0.797 ± 0.395
1.993ThrGlu: 1.993 ± 0.558
0.399ThrPhe: 0.399 ± 1.347
1.196ThrGly: 1.196 ± 0.953
2.79ThrHis: 2.79 ± 1.381
1.993ThrIle: 1.993 ± 2.103
0.797ThrLys: 0.797 ± 0.395
8.37ThrLeu: 8.37 ± 2.599
1.196ThrMet: 1.196 ± 0.592
0.797ThrAsn: 0.797 ± 0.395
1.196ThrPro: 1.196 ± 0.592
1.594ThrGln: 1.594 ± 0.789
3.587ThrArg: 3.587 ± 0.231
1.993ThrSer: 1.993 ± 0.558
1.993ThrThr: 1.993 ± 0.987
2.391ThrVal: 2.391 ± 1.184
0.399ThrTrp: 0.399 ± 0.197
4.384ThrTyr: 4.384 ± 0.626
0.0ThrXaa: 0.0 ± 0.0
Val
0.797ValAla: 0.797 ± 0.395
0.797ValCys: 0.797 ± 1.15
4.783ValAsp: 4.783 ± 0.721
3.587ValGlu: 3.587 ± 1.313
1.993ValPhe: 1.993 ± 0.987
2.79ValGly: 2.79 ± 0.163
0.0ValHis: 0.0 ± 0.0
0.797ValIle: 0.797 ± 0.395
5.181ValLys: 5.181 ± 1.02
8.768ValLeu: 8.768 ± 0.293
1.993ValMet: 1.993 ± 0.558
1.594ValAsn: 1.594 ± 0.755
1.196ValPro: 1.196 ± 0.592
0.797ValGln: 0.797 ± 0.395
2.391ValArg: 2.391 ± 1.184
5.58ValSer: 5.58 ± 1.218
1.993ValThr: 1.993 ± 0.558
3.189ValVal: 3.189 ± 1.578
1.196ValTrp: 1.196 ± 0.592
1.594ValTyr: 1.594 ± 0.789
0.0ValXaa: 0.0 ± 0.0
Trp
0.399TrpAla: 0.399 ± 0.197
0.0TrpCys: 0.0 ± 0.0
0.399TrpAsp: 0.399 ± 0.197
0.797TrpGlu: 0.797 ± 1.15
0.797TrpPhe: 0.797 ± 1.15
0.399TrpGly: 0.399 ± 0.197
0.399TrpHis: 0.399 ± 0.197
0.797TrpIle: 0.797 ± 0.395
0.399TrpLys: 0.399 ± 0.197
0.399TrpLeu: 0.399 ± 1.347
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.797TrpArg: 0.797 ± 0.395
0.797TrpSer: 0.797 ± 1.15
0.797TrpThr: 0.797 ± 0.395
0.399TrpVal: 0.399 ± 0.197
0.399TrpTrp: 0.399 ± 0.197
0.797TrpTyr: 0.797 ± 0.395
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
1.196TyrCys: 1.196 ± 0.592
3.587TyrAsp: 3.587 ± 0.231
3.587TyrGlu: 3.587 ± 0.231
3.587TyrPhe: 3.587 ± 0.231
0.797TyrGly: 0.797 ± 0.395
1.993TyrHis: 1.993 ± 0.558
3.587TyrIle: 3.587 ± 1.776
4.783TyrLys: 4.783 ± 2.266
9.566TyrLeu: 9.566 ± 3.191
1.196TyrMet: 1.196 ± 0.592
4.783TyrAsn: 4.783 ± 2.266
1.993TyrPro: 1.993 ± 0.558
1.196TyrGln: 1.196 ± 0.592
2.79TyrArg: 2.79 ± 1.381
4.783TyrSer: 4.783 ± 2.368
3.587TyrThr: 3.587 ± 1.313
2.79TyrVal: 2.79 ± 1.381
0.0TyrTrp: 0.0 ± 0.0
1.993TyrTyr: 1.993 ± 0.987
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2510 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski