Amino acid dipepetide frequency for Penicillium brevicompactum tetramycovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.397AlaAla: 11.397 ± 1.978
1.688AlaCys: 1.688 ± 0.744
7.598AlaAsp: 7.598 ± 2.818
7.176AlaGlu: 7.176 ± 0.875
4.643AlaPhe: 4.643 ± 0.809
9.287AlaGly: 9.287 ± 2.033
0.844AlaHis: 0.844 ± 0.413
5.91AlaIle: 5.91 ± 0.99
3.377AlaLys: 3.377 ± 1.353
7.176AlaLeu: 7.176 ± 1.642
2.533AlaMet: 2.533 ± 0.933
3.377AlaAsn: 3.377 ± 0.846
2.111AlaPro: 2.111 ± 1.088
2.955AlaGln: 2.955 ± 1.221
8.442AlaArg: 8.442 ± 0.767
7.176AlaSer: 7.176 ± 3.307
6.332AlaThr: 6.332 ± 2.011
10.975AlaVal: 10.975 ± 2.403
0.844AlaTrp: 0.844 ± 0.765
1.688AlaTyr: 1.688 ± 0.7
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.844CysAsp: 0.844 ± 0.413
0.844CysGlu: 0.844 ± 0.765
0.422CysPhe: 0.422 ± 0.285
1.266CysGly: 1.266 ± 0.818
0.422CysHis: 0.422 ± 0.374
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
2.111CysLeu: 2.111 ± 0.426
0.844CysMet: 0.844 ± 0.34
0.0CysAsn: 0.0 ± 0.0
0.422CysPro: 0.422 ± 0.285
1.688CysGln: 1.688 ± 0.744
1.266CysArg: 1.266 ± 0.513
0.844CysSer: 0.844 ± 0.34
0.0CysThr: 0.0 ± 0.0
1.266CysVal: 1.266 ± 0.629
0.0CysTrp: 0.0 ± 0.0
0.844CysTyr: 0.844 ± 0.349
0.0CysXaa: 0.0 ± 0.0
Asp
6.754AspAla: 6.754 ± 0.703
0.422AspCys: 0.422 ± 0.47
2.955AspAsp: 2.955 ± 0.67
5.91AspGlu: 5.91 ± 1.386
1.266AspPhe: 1.266 ± 0.2
5.065AspGly: 5.065 ± 1.193
2.533AspHis: 2.533 ± 1.094
3.799AspIle: 3.799 ± 0.657
5.065AspLys: 5.065 ± 1.744
3.799AspLeu: 3.799 ± 0.889
1.688AspMet: 1.688 ± 0.744
0.844AspAsn: 0.844 ± 0.34
5.065AspPro: 5.065 ± 1.676
1.266AspGln: 1.266 ± 0.503
6.332AspArg: 6.332 ± 2.078
1.688AspSer: 1.688 ± 1.012
5.065AspThr: 5.065 ± 0.491
8.864AspVal: 8.864 ± 1.55
0.844AspTrp: 0.844 ± 0.748
1.266AspTyr: 1.266 ± 0.743
0.0AspXaa: 0.0 ± 0.0
Glu
6.754GluAla: 6.754 ± 1.521
0.844GluCys: 0.844 ± 0.349
2.533GluAsp: 2.533 ± 0.784
3.377GluGlu: 3.377 ± 1.344
2.111GluPhe: 2.111 ± 1.103
2.111GluGly: 2.111 ± 0.493
2.533GluHis: 2.533 ± 0.857
1.688GluIle: 1.688 ± 0.883
1.688GluLys: 1.688 ± 0.348
4.643GluLeu: 4.643 ± 0.711
2.111GluMet: 2.111 ± 0.876
0.422GluAsn: 0.422 ± 0.374
1.688GluPro: 1.688 ± 0.348
0.422GluGln: 0.422 ± 0.285
4.221GluArg: 4.221 ± 1.207
3.377GluSer: 3.377 ± 0.696
2.111GluThr: 2.111 ± 0.739
2.955GluVal: 2.955 ± 0.665
0.844GluTrp: 0.844 ± 0.94
2.955GluTyr: 2.955 ± 0.964
0.0GluXaa: 0.0 ± 0.0
Phe
2.111PheAla: 2.111 ± 0.426
0.422PheCys: 0.422 ± 0.285
4.643PheAsp: 4.643 ± 1.085
0.422PheGlu: 0.422 ± 0.382
0.0PhePhe: 0.0 ± 0.0
3.799PheGly: 3.799 ± 0.657
0.422PheHis: 0.422 ± 0.285
1.688PheIle: 1.688 ± 0.826
0.844PheLys: 0.844 ± 0.547
3.799PheLeu: 3.799 ± 0.779
0.0PheMet: 0.0 ± 0.0
1.688PheAsn: 1.688 ± 0.348
0.422PhePro: 0.422 ± 0.382
0.422PheGln: 0.422 ± 0.285
0.844PheArg: 0.844 ± 0.349
1.688PheSer: 1.688 ± 1.53
4.643PheThr: 4.643 ± 1.733
4.221PheVal: 4.221 ± 2.145
0.422PheTrp: 0.422 ± 0.285
0.844PheTyr: 0.844 ± 0.57
0.0PheXaa: 0.0 ± 0.0
Gly
8.02GlyAla: 8.02 ± 2.539
1.266GlyCys: 1.266 ± 0.598
2.955GlyAsp: 2.955 ± 1.136
4.221GlyGlu: 4.221 ± 0.813
1.266GlyPhe: 1.266 ± 0.2
5.91GlyGly: 5.91 ± 1.651
2.955GlyHis: 2.955 ± 0.419
2.533GlyIle: 2.533 ± 0.767
2.955GlyLys: 2.955 ± 1.362
3.377GlyLeu: 3.377 ± 0.782
1.688GlyMet: 1.688 ± 0.415
1.266GlyAsn: 1.266 ± 0.503
5.488GlyPro: 5.488 ± 0.397
1.688GlyGln: 1.688 ± 0.76
8.442GlyArg: 8.442 ± 1.439
7.176GlySer: 7.176 ± 1.952
2.955GlyThr: 2.955 ± 0.617
8.02GlyVal: 8.02 ± 1.465
0.422GlyTrp: 0.422 ± 0.374
2.955GlyTyr: 2.955 ± 0.776
0.0GlyXaa: 0.0 ± 0.0
His
3.377HisAla: 3.377 ± 1.032
0.0HisCys: 0.0 ± 0.0
1.688HisAsp: 1.688 ± 0.552
1.266HisGlu: 1.266 ± 0.513
1.688HisPhe: 1.688 ± 0.507
2.111HisGly: 2.111 ± 1.481
0.844HisHis: 0.844 ± 0.765
0.844HisIle: 0.844 ± 0.34
0.0HisLys: 0.0 ± 0.0
2.533HisLeu: 2.533 ± 1.253
0.422HisMet: 0.422 ± 0.374
0.844HisAsn: 0.844 ± 0.34
0.422HisPro: 0.422 ± 0.285
1.266HisGln: 1.266 ± 0.2
1.688HisArg: 1.688 ± 0.68
1.688HisSer: 1.688 ± 0.826
0.422HisThr: 0.422 ± 0.285
1.688HisVal: 1.688 ± 0.883
0.422HisTrp: 0.422 ± 0.374
0.422HisTyr: 0.422 ± 0.374
0.0HisXaa: 0.0 ± 0.0
Ile
5.488IleAla: 5.488 ± 1.155
0.422IleCys: 0.422 ± 0.382
5.488IleAsp: 5.488 ± 1.287
0.844IleGlu: 0.844 ± 0.349
1.688IlePhe: 1.688 ± 0.507
2.955IleGly: 2.955 ± 0.566
0.422IleHis: 0.422 ± 0.374
1.266IleIle: 1.266 ± 0.2
0.844IleLys: 0.844 ± 0.57
3.377IleLeu: 3.377 ± 1.507
1.266IleMet: 1.266 ± 0.653
1.688IleAsn: 1.688 ± 0.507
1.688IlePro: 1.688 ± 0.287
0.422IleGln: 0.422 ± 0.285
2.955IleArg: 2.955 ± 1.026
0.844IleSer: 0.844 ± 0.493
1.688IleThr: 1.688 ± 0.436
3.799IleVal: 3.799 ± 0.456
0.0IleTrp: 0.0 ± 0.0
1.688IleTyr: 1.688 ± 0.436
0.0IleXaa: 0.0 ± 0.0
Lys
5.065LysAla: 5.065 ± 1.073
0.844LysCys: 0.844 ± 0.765
1.688LysAsp: 1.688 ± 1.012
0.844LysGlu: 0.844 ± 0.547
2.111LysPhe: 2.111 ± 0.804
2.111LysGly: 2.111 ± 0.753
0.422LysHis: 0.422 ± 0.285
3.377LysIle: 3.377 ± 0.969
0.844LysLys: 0.844 ± 0.94
2.533LysLeu: 2.533 ± 0.684
2.533LysMet: 2.533 ± 1.134
0.422LysAsn: 0.422 ± 0.382
1.266LysPro: 1.266 ± 0.473
0.844LysGln: 0.844 ± 0.413
2.111LysArg: 2.111 ± 1.14
2.533LysSer: 2.533 ± 1.047
1.266LysThr: 1.266 ± 0.656
2.111LysVal: 2.111 ± 0.876
1.266LysTrp: 1.266 ± 0.743
0.844LysTyr: 0.844 ± 0.547
0.0LysXaa: 0.0 ± 0.0
Leu
6.754LeuAla: 6.754 ± 1.299
0.422LeuCys: 0.422 ± 0.47
4.643LeuAsp: 4.643 ± 0.957
5.065LeuGlu: 5.065 ± 1.348
1.688LeuPhe: 1.688 ± 0.348
6.754LeuGly: 6.754 ± 1.137
2.111LeuHis: 2.111 ± 0.53
2.955LeuIle: 2.955 ± 0.762
2.533LeuLys: 2.533 ± 1.398
9.287LeuLeu: 9.287 ± 1.089
2.111LeuMet: 2.111 ± 0.81
3.799LeuAsn: 3.799 ± 0.22
5.065LeuPro: 5.065 ± 0.283
1.688LeuGln: 1.688 ± 0.552
7.176LeuArg: 7.176 ± 0.758
8.02LeuSer: 8.02 ± 1.234
4.221LeuThr: 4.221 ± 0.729
8.442LeuVal: 8.442 ± 1.048
0.0LeuTrp: 0.0 ± 0.0
0.844LeuTyr: 0.844 ± 0.748
0.0LeuXaa: 0.0 ± 0.0
Met
3.377MetAla: 3.377 ± 0.585
0.844MetCys: 0.844 ± 0.413
0.844MetAsp: 0.844 ± 0.34
0.422MetGlu: 0.422 ± 0.382
0.422MetPhe: 0.422 ± 0.285
0.844MetGly: 0.844 ± 0.34
0.422MetHis: 0.422 ± 0.285
0.0MetIle: 0.0 ± 0.0
1.266MetLys: 1.266 ± 0.503
4.221MetLeu: 4.221 ± 1.37
0.844MetMet: 0.844 ± 0.413
0.0MetAsn: 0.0 ± 0.0
2.111MetPro: 2.111 ± 0.53
0.422MetGln: 0.422 ± 0.285
0.422MetArg: 0.422 ± 0.374
3.799MetSer: 3.799 ± 1.031
0.422MetThr: 0.422 ± 0.285
2.111MetVal: 2.111 ± 0.493
0.0MetTrp: 0.0 ± 0.0
0.422MetTyr: 0.422 ± 0.382
0.0MetXaa: 0.0 ± 0.0
Asn
2.111AsnAla: 2.111 ± 0.406
0.0AsnCys: 0.0 ± 0.0
2.533AsnAsp: 2.533 ± 0.684
0.844AsnGlu: 0.844 ± 0.557
0.422AsnPhe: 0.422 ± 0.382
2.955AsnGly: 2.955 ± 1.026
0.844AsnHis: 0.844 ± 0.748
0.0AsnIle: 0.0 ± 0.0
2.955AsnLys: 2.955 ± 0.665
0.422AsnLeu: 0.422 ± 0.285
0.422AsnMet: 0.422 ± 0.285
1.688AsnAsn: 1.688 ± 0.7
2.111AsnPro: 2.111 ± 0.604
1.266AsnGln: 1.266 ± 0.503
2.111AsnArg: 2.111 ± 1.017
1.688AsnSer: 1.688 ± 0.436
1.266AsnThr: 1.266 ± 0.2
1.266AsnVal: 1.266 ± 0.614
0.0AsnTrp: 0.0 ± 0.0
1.266AsnTyr: 1.266 ± 0.476
0.0AsnXaa: 0.0 ± 0.0
Pro
7.598ProAla: 7.598 ± 2.555
1.266ProCys: 1.266 ± 0.656
3.377ProAsp: 3.377 ± 0.687
2.533ProGlu: 2.533 ± 0.877
2.111ProPhe: 2.111 ± 1.14
4.643ProGly: 4.643 ± 0.852
0.844ProHis: 0.844 ± 0.349
2.111ProIle: 2.111 ± 0.987
2.955ProLys: 2.955 ± 1.556
3.377ProLeu: 3.377 ± 0.494
0.422ProMet: 0.422 ± 0.374
1.688ProAsn: 1.688 ± 0.876
3.377ProPro: 3.377 ± 1.006
1.266ProGln: 1.266 ± 0.598
2.533ProArg: 2.533 ± 1.094
5.065ProSer: 5.065 ± 1.037
2.955ProThr: 2.955 ± 1.181
5.065ProVal: 5.065 ± 1.205
0.0ProTrp: 0.0 ± 0.0
1.688ProTyr: 1.688 ± 1.154
0.0ProXaa: 0.0 ± 0.0
Gln
2.533GlnAla: 2.533 ± 0.727
0.422GlnCys: 0.422 ± 0.285
0.844GlnAsp: 0.844 ± 0.34
1.688GlnGlu: 1.688 ± 0.744
1.266GlnPhe: 1.266 ± 0.2
2.111GlnGly: 2.111 ± 0.53
0.422GlnHis: 0.422 ± 0.285
0.844GlnIle: 0.844 ± 0.57
1.688GlnLys: 1.688 ± 0.625
2.955GlnLeu: 2.955 ± 0.796
0.422GlnMet: 0.422 ± 0.285
0.422GlnAsn: 0.422 ± 0.374
1.266GlnPro: 1.266 ± 0.2
1.266GlnGln: 1.266 ± 0.473
0.844GlnArg: 0.844 ± 0.57
1.688GlnSer: 1.688 ± 0.287
0.844GlnThr: 0.844 ± 0.349
2.533GlnVal: 2.533 ± 0.442
0.844GlnTrp: 0.844 ± 0.413
1.266GlnTyr: 1.266 ± 0.476
0.0GlnXaa: 0.0 ± 0.0
Arg
8.442ArgAla: 8.442 ± 1.484
1.266ArgCys: 1.266 ± 0.818
3.799ArgAsp: 3.799 ± 1.705
3.377ArgGlu: 3.377 ± 1.627
2.955ArgPhe: 2.955 ± 0.796
5.065ArgGly: 5.065 ± 1.479
3.377ArgHis: 3.377 ± 0.213
3.377ArgIle: 3.377 ± 1.533
2.955ArgLys: 2.955 ± 1.427
7.598ArgLeu: 7.598 ± 1.403
1.266ArgMet: 1.266 ± 0.503
2.111ArgAsn: 2.111 ± 0.406
2.533ArgPro: 2.533 ± 1.253
2.955ArgGln: 2.955 ± 0.796
5.065ArgArg: 5.065 ± 1.252
7.598ArgSer: 7.598 ± 0.853
5.065ArgThr: 5.065 ± 0.623
7.176ArgVal: 7.176 ± 1.215
0.422ArgTrp: 0.422 ± 0.374
1.266ArgTyr: 1.266 ± 0.598
0.0ArgXaa: 0.0 ± 0.0
Ser
6.754SerAla: 6.754 ± 1.45
1.266SerCys: 1.266 ± 1.123
5.91SerAsp: 5.91 ± 0.312
1.688SerGlu: 1.688 ± 0.552
2.955SerPhe: 2.955 ± 1.22
5.065SerGly: 5.065 ± 1.48
0.844SerHis: 0.844 ± 0.547
1.688SerIle: 1.688 ± 0.955
1.688SerLys: 1.688 ± 0.826
5.91SerLeu: 5.91 ± 1.047
0.844SerMet: 0.844 ± 0.748
0.844SerAsn: 0.844 ± 0.765
6.754SerPro: 6.754 ± 1.149
0.844SerGln: 0.844 ± 0.349
8.02SerArg: 8.02 ± 0.772
6.332SerSer: 6.332 ± 1.557
5.488SerThr: 5.488 ± 1.446
8.02SerVal: 8.02 ± 2.196
0.422SerTrp: 0.422 ± 0.285
2.533SerTyr: 2.533 ± 0.949
0.0SerXaa: 0.0 ± 0.0
Thr
7.176ThrAla: 7.176 ± 1.588
0.422ThrCys: 0.422 ± 0.374
2.955ThrAsp: 2.955 ± 0.796
2.533ThrGlu: 2.533 ± 1.375
1.266ThrPhe: 1.266 ± 0.614
4.221ThrGly: 4.221 ± 0.852
1.688ThrHis: 1.688 ± 0.436
2.955ThrIle: 2.955 ± 0.491
0.844ThrLys: 0.844 ± 0.349
5.065ThrLeu: 5.065 ± 1.127
0.844ThrMet: 0.844 ± 0.349
1.266ThrAsn: 1.266 ± 0.656
4.221ThrPro: 4.221 ± 1.407
2.111ThrGln: 2.111 ± 0.876
5.065ThrArg: 5.065 ± 0.994
5.488ThrSer: 5.488 ± 0.91
2.111ThrThr: 2.111 ± 0.996
5.065ThrVal: 5.065 ± 1.318
0.844ThrTrp: 0.844 ± 0.413
1.266ThrTyr: 1.266 ± 0.476
0.0ThrXaa: 0.0 ± 0.0
Val
8.442ValAla: 8.442 ± 1.834
0.844ValCys: 0.844 ± 0.765
11.397ValAsp: 11.397 ± 1.993
3.799ValGlu: 3.799 ± 0.889
5.065ValPhe: 5.065 ± 2.079
6.754ValGly: 6.754 ± 1.254
1.266ValHis: 1.266 ± 0.855
2.111ValIle: 2.111 ± 0.53
2.533ValLys: 2.533 ± 0.82
8.442ValLeu: 8.442 ± 0.769
2.111ValMet: 2.111 ± 0.604
2.533ValAsn: 2.533 ± 0.889
7.176ValPro: 7.176 ± 2.23
2.955ValGln: 2.955 ± 0.796
8.442ValArg: 8.442 ± 0.996
3.799ValSer: 3.799 ± 1.852
7.176ValThr: 7.176 ± 1.015
9.709ValVal: 9.709 ± 1.72
0.844ValTrp: 0.844 ± 0.57
1.688ValTyr: 1.688 ± 0.955
0.0ValXaa: 0.0 ± 0.0
Trp
0.422TrpAla: 0.422 ± 0.47
0.422TrpCys: 0.422 ± 0.285
1.266TrpAsp: 1.266 ± 0.653
0.844TrpGlu: 0.844 ± 0.349
0.0TrpPhe: 0.0 ± 0.0
0.844TrpGly: 0.844 ± 0.34
0.0TrpHis: 0.0 ± 0.0
0.422TrpIle: 0.422 ± 0.374
0.0TrpLys: 0.0 ± 0.0
0.422TrpLeu: 0.422 ± 0.285
0.0TrpMet: 0.0 ± 0.309
0.422TrpAsn: 0.422 ± 0.374
0.844TrpPro: 0.844 ± 0.349
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
1.266TrpThr: 1.266 ± 1.147
0.844TrpVal: 0.844 ± 0.57
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.955TyrAla: 2.955 ± 1.556
0.0TyrCys: 0.0 ± 0.0
2.533TyrAsp: 2.533 ± 0.784
1.688TyrGlu: 1.688 ± 0.698
0.0TyrPhe: 0.0 ± 0.0
1.688TyrGly: 1.688 ± 0.507
0.422TyrHis: 0.422 ± 0.374
1.266TyrIle: 1.266 ± 1.123
0.0TyrLys: 0.0 ± 0.0
2.533TyrLeu: 2.533 ± 1.281
0.422TyrMet: 0.422 ± 0.374
0.844TyrAsn: 0.844 ± 0.34
0.844TyrPro: 0.844 ± 0.34
0.422TyrGln: 0.422 ± 0.374
1.688TyrArg: 1.688 ± 0.84
3.377TyrSer: 3.377 ± 0.86
2.111TyrThr: 2.111 ± 1.378
2.955TyrVal: 2.955 ± 0.946
0.0TyrTrp: 0.0 ± 0.0
1.266TyrTyr: 1.266 ± 1.123
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (2370 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski