Amino acid dipepetide frequency for Odocoileus virginianus papillomavirus 1 (DPV) (Deer papillomavirus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.53AlaAla: 4.53 ± 1.099
2.883AlaCys: 2.883 ± 1.378
4.53AlaAsp: 4.53 ± 0.985
3.707AlaGlu: 3.707 ± 0.997
2.059AlaPhe: 2.059 ± 0.693
4.119AlaGly: 4.119 ± 1.466
1.236AlaHis: 1.236 ± 0.691
0.824AlaIle: 0.824 ± 0.476
2.883AlaLys: 2.883 ± 1.477
4.942AlaLeu: 4.942 ± 1.573
0.0AlaMet: 0.0 ± 0.0
3.295AlaAsn: 3.295 ± 1.147
5.354AlaPro: 5.354 ± 1.953
1.647AlaGln: 1.647 ± 0.639
5.354AlaArg: 5.354 ± 1.514
2.471AlaSer: 2.471 ± 1.584
4.119AlaThr: 4.119 ± 1.136
4.53AlaVal: 4.53 ± 1.091
0.824AlaTrp: 0.824 ± 0.703
2.471AlaTyr: 2.471 ± 0.877
0.0AlaXaa: 0.0 ± 0.0
Cys
1.647CysAla: 1.647 ± 0.839
0.824CysCys: 0.824 ± 0.642
1.236CysAsp: 1.236 ± 0.675
0.824CysGlu: 0.824 ± 0.688
0.824CysPhe: 0.824 ± 0.584
0.824CysGly: 0.824 ± 0.747
0.412CysHis: 0.412 ± 0.321
1.236CysIle: 1.236 ± 0.753
0.412CysLys: 0.412 ± 0.383
2.883CysLeu: 2.883 ± 0.944
1.236CysMet: 1.236 ± 0.573
2.059CysAsn: 2.059 ± 1.019
1.236CysPro: 1.236 ± 0.379
0.0CysGln: 0.0 ± 0.0
1.236CysArg: 1.236 ± 0.597
4.53CysSer: 4.53 ± 1.404
2.059CysThr: 2.059 ± 0.954
1.647CysVal: 1.647 ± 1.02
0.824CysTrp: 0.824 ± 0.412
1.647CysTyr: 1.647 ± 1.515
0.0CysXaa: 0.0 ± 0.0
Asp
4.53AspAla: 4.53 ± 1.092
2.471AspCys: 2.471 ± 1.125
2.471AspAsp: 2.471 ± 0.891
4.942AspGlu: 4.942 ± 1.15
1.236AspPhe: 1.236 ± 0.702
3.295AspGly: 3.295 ± 0.963
1.647AspHis: 1.647 ± 0.701
2.883AspIle: 2.883 ± 1.162
3.295AspLys: 3.295 ± 1.197
4.53AspLeu: 4.53 ± 0.736
0.412AspMet: 0.412 ± 0.319
3.295AspAsn: 3.295 ± 0.702
2.471AspPro: 2.471 ± 0.694
2.883AspGln: 2.883 ± 0.546
2.883AspArg: 2.883 ± 1.042
2.883AspSer: 2.883 ± 0.681
2.471AspThr: 2.471 ± 0.934
1.236AspVal: 1.236 ± 0.359
0.412AspTrp: 0.412 ± 0.321
0.824AspTyr: 0.824 ± 0.534
0.0AspXaa: 0.0 ± 0.0
Glu
5.766GluAla: 5.766 ± 1.698
0.824GluCys: 0.824 ± 0.642
3.295GluAsp: 3.295 ± 0.78
4.942GluGlu: 4.942 ± 1.13
0.824GluPhe: 0.824 ± 0.41
3.707GluGly: 3.707 ± 2.258
1.647GluHis: 1.647 ± 0.532
1.647GluIle: 1.647 ± 0.641
3.707GluLys: 3.707 ± 1.327
5.354GluLeu: 5.354 ± 1.481
0.824GluMet: 0.824 ± 0.476
2.883GluAsn: 2.883 ± 0.507
4.119GluPro: 4.119 ± 0.694
2.471GluGln: 2.471 ± 0.662
4.119GluArg: 4.119 ± 1.175
2.883GluSer: 2.883 ± 0.901
4.119GluThr: 4.119 ± 1.757
4.53GluVal: 4.53 ± 0.979
0.412GluTrp: 0.412 ± 0.321
2.883GluTyr: 2.883 ± 0.841
0.0GluXaa: 0.0 ± 0.0
Phe
2.059PheAla: 2.059 ± 0.852
0.824PheCys: 0.824 ± 0.844
2.059PheAsp: 2.059 ± 0.845
2.471PheGlu: 2.471 ± 0.782
1.647PhePhe: 1.647 ± 0.955
2.471PheGly: 2.471 ± 0.581
0.412PheHis: 0.412 ± 0.383
2.471PheIle: 2.471 ± 0.85
2.471PheLys: 2.471 ± 0.934
3.295PheLeu: 3.295 ± 0.839
0.412PheMet: 0.412 ± 0.352
2.471PheAsn: 2.471 ± 0.913
0.412PhePro: 0.412 ± 0.319
1.236PheGln: 1.236 ± 0.611
2.059PheArg: 2.059 ± 0.77
2.471PheSer: 2.471 ± 0.563
1.647PheThr: 1.647 ± 1.079
1.236PheVal: 1.236 ± 0.379
1.647PheTrp: 1.647 ± 0.825
1.647PheTyr: 1.647 ± 0.59
0.0PheXaa: 0.0 ± 0.0
Gly
2.883GlyAla: 2.883 ± 1.153
0.412GlyCys: 0.412 ± 0.319
2.059GlyAsp: 2.059 ± 0.733
6.178GlyGlu: 6.178 ± 1.341
1.236GlyPhe: 1.236 ± 0.429
8.649GlyGly: 8.649 ± 2.984
0.412GlyHis: 0.412 ± 0.319
3.707GlyIle: 3.707 ± 1.489
2.883GlyLys: 2.883 ± 1.363
4.942GlyLeu: 4.942 ± 2.208
2.471GlyMet: 2.471 ± 1.182
2.471GlyAsn: 2.471 ± 1.086
4.53GlyPro: 4.53 ± 1.68
2.883GlyGln: 2.883 ± 1.517
5.354GlyArg: 5.354 ± 1.784
9.885GlySer: 9.885 ± 2.498
4.942GlyThr: 4.942 ± 0.886
5.766GlyVal: 5.766 ± 1.41
1.236GlyTrp: 1.236 ± 0.764
1.647GlyTyr: 1.647 ± 0.783
0.0GlyXaa: 0.0 ± 0.0
His
0.824HisAla: 0.824 ± 0.396
0.412HisCys: 0.412 ± 0.414
0.824HisAsp: 0.824 ± 0.48
1.647HisGlu: 1.647 ± 0.791
1.236HisPhe: 1.236 ± 0.667
4.119HisGly: 4.119 ± 1.02
1.236HisHis: 1.236 ± 0.658
1.647HisIle: 1.647 ± 0.619
1.236HisLys: 1.236 ± 0.429
2.471HisLeu: 2.471 ± 1.019
0.412HisMet: 0.412 ± 0.319
0.824HisAsn: 0.824 ± 0.412
0.824HisPro: 0.824 ± 0.766
0.412HisGln: 0.412 ± 0.321
2.059HisArg: 2.059 ± 1.176
2.883HisSer: 2.883 ± 1.162
1.236HisThr: 1.236 ± 0.429
0.412HisVal: 0.412 ± 0.319
0.0HisTrp: 0.0 ± 0.0
1.236HisTyr: 1.236 ± 0.699
0.0HisXaa: 0.0 ± 0.0
Ile
3.295IleAla: 3.295 ± 1.354
0.824IleCys: 0.824 ± 0.637
3.707IleAsp: 3.707 ± 1.13
4.119IleGlu: 4.119 ± 1.046
2.471IlePhe: 2.471 ± 1.486
1.647IleGly: 1.647 ± 0.846
0.0IleHis: 0.0 ± 0.0
1.647IleIle: 1.647 ± 1.532
0.412IleLys: 0.412 ± 0.321
4.942IleLeu: 4.942 ± 1.848
0.824IleMet: 0.824 ± 0.408
2.883IleAsn: 2.883 ± 0.624
2.059IlePro: 2.059 ± 0.779
2.471IleGln: 2.471 ± 1.04
1.647IleArg: 1.647 ± 0.993
2.059IleSer: 2.059 ± 0.633
4.119IleThr: 4.119 ± 1.604
1.236IleVal: 1.236 ± 0.658
0.824IleTrp: 0.824 ± 0.476
0.824IleTyr: 0.824 ± 0.41
0.0IleXaa: 0.0 ± 0.0
Lys
2.471LysAla: 2.471 ± 0.701
1.647LysCys: 1.647 ± 0.766
2.883LysAsp: 2.883 ± 1.245
4.942LysGlu: 4.942 ± 1.622
1.236LysPhe: 1.236 ± 0.663
2.883LysGly: 2.883 ± 1.215
1.647LysHis: 1.647 ± 0.57
1.236LysIle: 1.236 ± 0.753
1.236LysLys: 1.236 ± 0.626
2.883LysLeu: 2.883 ± 1.466
1.236LysMet: 1.236 ± 0.865
0.824LysAsn: 0.824 ± 1.225
2.883LysPro: 2.883 ± 1.261
1.236LysGln: 1.236 ± 0.663
4.942LysArg: 4.942 ± 1.64
1.647LysSer: 1.647 ± 0.962
2.883LysThr: 2.883 ± 0.864
3.295LysVal: 3.295 ± 1.137
0.0LysTrp: 0.0 ± 0.0
2.471LysTyr: 2.471 ± 1.031
0.0LysXaa: 0.0 ± 0.0
Leu
3.295LeuAla: 3.295 ± 0.957
3.295LeuCys: 3.295 ± 0.77
4.53LeuAsp: 4.53 ± 1.462
6.59LeuGlu: 6.59 ± 1.753
5.354LeuPhe: 5.354 ± 1.262
4.53LeuGly: 4.53 ± 0.976
1.647LeuHis: 1.647 ± 0.692
4.119LeuIle: 4.119 ± 1.19
6.178LeuLys: 6.178 ± 1.33
7.414LeuLeu: 7.414 ± 1.23
1.236LeuMet: 1.236 ± 0.379
2.471LeuAsn: 2.471 ± 0.852
5.354LeuPro: 5.354 ± 2.035
4.53LeuGln: 4.53 ± 0.828
4.53LeuArg: 4.53 ± 1.307
5.354LeuSer: 5.354 ± 1.149
7.002LeuThr: 7.002 ± 2.588
2.883LeuVal: 2.883 ± 0.75
0.824LeuTrp: 0.824 ± 0.404
5.766LeuTyr: 5.766 ± 1.263
0.0LeuXaa: 0.0 ± 0.0
Met
1.236MetAla: 1.236 ± 0.685
0.412MetCys: 0.412 ± 0.492
1.236MetAsp: 1.236 ± 0.663
0.412MetGlu: 0.412 ± 0.319
1.647MetPhe: 1.647 ± 0.59
0.824MetGly: 0.824 ± 0.766
1.236MetHis: 1.236 ± 1.344
0.0MetIle: 0.0 ± 0.0
0.412MetLys: 0.412 ± 0.321
0.824MetLeu: 0.824 ± 0.637
0.412MetMet: 0.412 ± 0.319
0.824MetAsn: 0.824 ± 0.412
1.236MetPro: 1.236 ± 0.627
0.824MetGln: 0.824 ± 0.776
0.412MetArg: 0.412 ± 0.319
3.295MetSer: 3.295 ± 1.716
1.647MetThr: 1.647 ± 0.735
0.824MetVal: 0.824 ± 0.642
0.0MetTrp: 0.0 ± 0.0
0.412MetTyr: 0.412 ± 0.492
0.0MetXaa: 0.0 ± 0.0
Asn
3.707AsnAla: 3.707 ± 1.571
0.824AsnCys: 0.824 ± 0.642
1.647AsnAsp: 1.647 ± 0.641
0.412AsnGlu: 0.412 ± 0.414
1.236AsnPhe: 1.236 ± 0.685
1.647AsnGly: 1.647 ± 0.638
2.059AsnHis: 2.059 ± 1.194
1.236AsnIle: 1.236 ± 0.709
0.824AsnLys: 0.824 ± 0.404
1.647AsnLeu: 1.647 ± 0.825
1.236AsnMet: 1.236 ± 0.761
1.236AsnAsn: 1.236 ± 0.956
3.707AsnPro: 3.707 ± 1.426
1.647AsnGln: 1.647 ± 0.769
2.471AsnArg: 2.471 ± 0.657
4.119AsnSer: 4.119 ± 1.51
3.295AsnThr: 3.295 ± 1.087
3.707AsnVal: 3.707 ± 1.671
0.824AsnTrp: 0.824 ± 0.41
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.707ProAla: 3.707 ± 1.016
2.883ProCys: 2.883 ± 0.933
5.766ProAsp: 5.766 ± 2.03
4.53ProGlu: 4.53 ± 2.095
2.059ProPhe: 2.059 ± 0.828
4.53ProGly: 4.53 ± 1.226
0.0ProHis: 0.0 ± 0.0
2.059ProIle: 2.059 ± 1.159
2.471ProLys: 2.471 ± 0.563
7.414ProLeu: 7.414 ± 2.217
0.412ProMet: 0.412 ± 0.321
2.883ProAsn: 2.883 ± 0.75
8.237ProPro: 8.237 ± 2.506
2.471ProGln: 2.471 ± 1.188
2.059ProArg: 2.059 ± 1.689
6.178ProSer: 6.178 ± 1.342
6.178ProThr: 6.178 ± 3.205
5.766ProVal: 5.766 ± 1.384
2.059ProTrp: 2.059 ± 0.583
2.059ProTyr: 2.059 ± 0.682
0.0ProXaa: 0.0 ± 0.0
Gln
2.883GlnAla: 2.883 ± 0.98
0.412GlnCys: 0.412 ± 0.321
0.824GlnAsp: 0.824 ± 0.766
2.059GlnGlu: 2.059 ± 0.739
1.647GlnPhe: 1.647 ± 0.955
4.119GlnGly: 4.119 ± 0.889
0.412GlnHis: 0.412 ± 0.414
1.236GlnIle: 1.236 ± 0.624
2.059GlnLys: 2.059 ± 0.847
2.059GlnLeu: 2.059 ± 0.832
0.824GlnMet: 0.824 ± 0.665
0.412GlnAsn: 0.412 ± 0.414
3.707GlnPro: 3.707 ± 0.906
2.883GlnGln: 2.883 ± 0.628
1.647GlnArg: 1.647 ± 0.701
3.707GlnSer: 3.707 ± 1.585
1.647GlnThr: 1.647 ± 0.892
3.295GlnVal: 3.295 ± 0.836
0.824GlnTrp: 0.824 ± 0.642
1.236GlnTyr: 1.236 ± 0.806
0.0GlnXaa: 0.0 ± 0.0
Arg
3.295ArgAla: 3.295 ± 0.804
3.295ArgCys: 3.295 ± 2.012
3.295ArgAsp: 3.295 ± 1.197
1.647ArgGlu: 1.647 ± 1.193
0.824ArgPhe: 0.824 ± 0.476
6.178ArgGly: 6.178 ± 1.146
3.707ArgHis: 3.707 ± 1.116
1.236ArgIle: 1.236 ± 0.618
3.707ArgLys: 3.707 ± 0.777
5.354ArgLeu: 5.354 ± 0.981
1.236ArgMet: 1.236 ± 1.29
1.647ArgAsn: 1.647 ± 0.708
7.002ArgPro: 7.002 ± 2.561
2.059ArgGln: 2.059 ± 0.777
4.53ArgArg: 4.53 ± 2.27
1.647ArgSer: 1.647 ± 1.193
2.883ArgThr: 2.883 ± 1.013
4.53ArgVal: 4.53 ± 0.563
1.236ArgTrp: 1.236 ± 0.359
2.471ArgTyr: 2.471 ± 0.927
0.0ArgXaa: 0.0 ± 0.0
Ser
4.53SerAla: 4.53 ± 1.205
0.824SerCys: 0.824 ± 0.641
2.883SerAsp: 2.883 ± 1.138
3.295SerGlu: 3.295 ± 0.957
2.883SerPhe: 2.883 ± 0.603
8.649SerGly: 8.649 ± 1.648
2.059SerHis: 2.059 ± 0.972
5.766SerIle: 5.766 ± 1.283
3.295SerLys: 3.295 ± 1.243
7.414SerLeu: 7.414 ± 2.048
2.471SerMet: 2.471 ± 0.918
1.647SerAsn: 1.647 ± 0.892
7.002SerPro: 7.002 ± 2.161
1.647SerGln: 1.647 ± 0.875
4.53SerArg: 4.53 ± 1.535
5.354SerSer: 5.354 ± 1.787
7.414SerThr: 7.414 ± 2.441
2.471SerVal: 2.471 ± 0.964
1.647SerTrp: 1.647 ± 0.808
0.824SerTyr: 0.824 ± 0.41
0.0SerXaa: 0.0 ± 0.0
Thr
4.942ThrAla: 4.942 ± 1.948
1.647ThrCys: 1.647 ± 0.866
3.295ThrAsp: 3.295 ± 1.339
2.471ThrGlu: 2.471 ± 0.924
1.647ThrPhe: 1.647 ± 0.265
4.53ThrGly: 4.53 ± 1.224
2.059ThrHis: 2.059 ± 0.883
3.707ThrIle: 3.707 ± 0.925
2.059ThrLys: 2.059 ± 1.593
6.178ThrLeu: 6.178 ± 1.713
2.059ThrMet: 2.059 ± 0.988
1.647ThrAsn: 1.647 ± 0.964
6.59ThrPro: 6.59 ± 1.511
2.471ThrGln: 2.471 ± 0.85
3.295ThrArg: 3.295 ± 1.316
6.178ThrSer: 6.178 ± 1.699
4.942ThrThr: 4.942 ± 1.619
8.237ThrVal: 8.237 ± 1.016
1.236ThrTrp: 1.236 ± 1.241
1.647ThrTyr: 1.647 ± 0.692
0.0ThrXaa: 0.0 ± 0.0
Val
3.295ValAla: 3.295 ± 1.082
0.824ValCys: 0.824 ± 0.534
2.059ValAsp: 2.059 ± 0.775
3.295ValGlu: 3.295 ± 0.665
2.059ValPhe: 2.059 ± 0.623
5.766ValGly: 5.766 ± 2.045
1.236ValHis: 1.236 ± 0.601
2.471ValIle: 2.471 ± 0.852
3.295ValLys: 3.295 ± 1.128
7.002ValLeu: 7.002 ± 1.516
0.0ValMet: 0.0 ± 0.0
1.647ValAsn: 1.647 ± 0.962
4.942ValPro: 4.942 ± 1.09
2.471ValGln: 2.471 ± 1.584
4.942ValArg: 4.942 ± 0.973
4.53ValSer: 4.53 ± 1.962
5.354ValThr: 5.354 ± 1.084
2.883ValVal: 2.883 ± 1.371
0.412ValTrp: 0.412 ± 0.319
2.471ValTyr: 2.471 ± 0.501
0.0ValXaa: 0.0 ± 0.0
Trp
2.059TrpAla: 2.059 ± 0.703
0.412TrpCys: 0.412 ± 0.414
0.0TrpAsp: 0.0 ± 0.0
1.236TrpGlu: 1.236 ± 0.697
0.824TrpPhe: 0.824 ± 0.396
1.647TrpGly: 1.647 ± 0.735
0.412TrpHis: 0.412 ± 0.414
0.824TrpIle: 0.824 ± 0.412
0.824TrpLys: 0.824 ± 0.396
2.059TrpLeu: 2.059 ± 0.739
0.0TrpMet: 0.0 ± 0.0
1.236TrpAsn: 1.236 ± 0.833
0.0TrpPro: 0.0 ± 0.0
0.412TrpGln: 0.412 ± 0.319
0.824TrpArg: 0.824 ± 0.396
1.647TrpSer: 1.647 ± 0.623
1.236TrpThr: 1.236 ± 0.697
0.412TrpVal: 0.412 ± 0.321
0.412TrpTrp: 0.412 ± 0.414
0.412TrpTyr: 0.412 ± 0.414
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.824TyrAla: 0.824 ± 0.404
1.647TyrCys: 1.647 ± 1.499
2.471TyrAsp: 2.471 ± 0.565
1.236TyrGlu: 1.236 ± 0.586
2.471TyrPhe: 2.471 ± 0.86
0.412TyrGly: 0.412 ± 0.321
2.471TyrHis: 2.471 ± 0.546
2.059TyrIle: 2.059 ± 0.693
0.824TyrLys: 0.824 ± 0.41
3.295TyrLeu: 3.295 ± 0.758
0.0TyrMet: 0.0 ± 0.0
0.824TyrAsn: 0.824 ± 0.685
2.059TyrPro: 2.059 ± 0.651
1.236TyrGln: 1.236 ± 0.626
2.883TyrArg: 2.883 ± 0.936
2.883TyrSer: 2.883 ± 0.894
2.059TyrThr: 2.059 ± 1.166
2.059TyrVal: 2.059 ± 1.135
1.236TyrTrp: 1.236 ± 0.627
2.059TyrTyr: 2.059 ± 0.77
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (2429 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski