Amino acid dipepetide frequency for Sporocytophaga myxococcoides

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.256AlaAla: 4.256 ± 0.069	0.637AlaCys: 0.637 ± 0.02	3.303AlaAsp: 3.303 ± 0.047	3.927AlaGlu: 3.927 ± 0.058	3.118AlaPhe: 3.118 ± 0.046	4.964AlaGly: 4.964 ± 0.083	1.02AlaHis: 1.02 ± 0.023	4.832AlaIle: 4.832 ± 0.057	4.163AlaLys: 4.163 ± 0.068	5.719AlaLeu: 5.719 ± 0.075	1.384AlaMet: 1.384 ± 0.029	3.189AlaAsn: 3.189 ± 0.062	2.137AlaPro: 2.137 ± 0.046	2.056AlaGln: 2.056 ± 0.034	2.007AlaArg: 2.007 ± 0.039	4.543AlaSer: 4.543 ± 0.067	3.408AlaThr: 3.408 ± 0.086	3.838AlaVal: 3.838 ± 0.052	0.593AlaTrp: 0.593 ± 0.019	2.39AlaTyr: 2.39 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	0.508CysAla: 0.508 ± 0.025	0.138CysCys: 0.138 ± 0.008	0.451CysAsp: 0.451 ± 0.018	0.511CysGlu: 0.511 ± 0.019	0.471CysPhe: 0.471 ± 0.019	0.702CysGly: 0.702 ± 0.027	0.193CysHis: 0.193 ± 0.012	0.746CysIle: 0.746 ± 0.021	0.657CysLys: 0.657 ± 0.023	0.767CysLeu: 0.767 ± 0.023	0.208CysMet: 0.208 ± 0.012	0.543CysAsn: 0.543 ± 0.027	0.431CysPro: 0.431 ± 0.02	0.273CysGln: 0.273 ± 0.013	0.31CysArg: 0.31 ± 0.013	0.743CysSer: 0.743 ± 0.027	0.464CysThr: 0.464 ± 0.021	0.447CysVal: 0.447 ± 0.016	0.086CysTrp: 0.086 ± 0.007	0.388CysTyr: 0.388 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	3.13AspAla: 3.13 ± 0.049	0.456AspCys: 0.456 ± 0.019	2.338AspAsp: 2.338 ± 0.043	3.233AspGlu: 3.233 ± 0.05	3.242AspPhe: 3.242 ± 0.047	3.603AspGly: 3.603 ± 0.064	0.945AspHis: 0.945 ± 0.025	4.388AspIle: 4.388 ± 0.057	4.302AspLys: 4.302 ± 0.063	5.4AspLeu: 5.4 ± 0.062	1.016AspMet: 1.016 ± 0.026	2.955AspAsn: 2.955 ± 0.042	2.074AspPro: 2.074 ± 0.038	1.749AspGln: 1.749 ± 0.034	1.795AspArg: 1.795 ± 0.032	3.4AspSer: 3.4 ± 0.05	2.557AspThr: 2.557 ± 0.053	2.991AspVal: 2.991 ± 0.043	0.641AspTrp: 0.641 ± 0.017	2.491AspTyr: 2.491 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	4.022GluAla: 4.022 ± 0.063	0.425GluCys: 0.425 ± 0.015	3.258GluAsp: 3.258 ± 0.053	5.005GluGlu: 5.005 ± 0.098	2.995GluPhe: 2.995 ± 0.044	3.923GluGly: 3.923 ± 0.059	1.024GluHis: 1.024 ± 0.027	5.591GluIle: 5.591 ± 0.072	6.052GluLys: 6.052 ± 0.1	5.969GluLeu: 5.969 ± 0.095	1.526GluMet: 1.526 ± 0.032	3.984GluAsn: 3.984 ± 0.059	1.553GluPro: 1.553 ± 0.032	1.99GluGln: 1.99 ± 0.043	2.574GluArg: 2.574 ± 0.053	3.623GluSer: 3.623 ± 0.058	3.061GluThr: 3.061 ± 0.049	4.117GluVal: 4.117 ± 0.057	0.692GluTrp: 0.692 ± 0.021	2.548GluTyr: 2.548 ± 0.041	0.0GluXaa: 0.0 ± 0.0
Phe	2.868PheAla: 2.868 ± 0.04	0.518PheCys: 0.518 ± 0.017	2.929PheAsp: 2.929 ± 0.049	3.13PheGlu: 3.13 ± 0.053	2.867PhePhe: 2.867 ± 0.059	3.251PheGly: 3.251 ± 0.051	0.929PheHis: 0.929 ± 0.026	4.229PheIle: 4.229 ± 0.063	3.659PheLys: 3.659 ± 0.049	4.9PheLeu: 4.9 ± 0.07	1.007PheMet: 1.007 ± 0.026	3.243PheAsn: 3.243 ± 0.05	1.847PhePro: 1.847 ± 0.034	1.524PheGln: 1.524 ± 0.03	1.938PheArg: 1.938 ± 0.035	4.316PheSer: 4.316 ± 0.061	2.977PheThr: 2.977 ± 0.052	2.923PheVal: 2.923 ± 0.039	0.57PheTrp: 0.57 ± 0.022	2.439PheTyr: 2.439 ± 0.047	0.0PheXaa: 0.0 ± 0.0
Gly	4.188GlyAla: 4.188 ± 0.072	0.771GlyCys: 0.771 ± 0.036	3.217GlyAsp: 3.217 ± 0.048	3.606GlyGlu: 3.606 ± 0.049	3.435GlyPhe: 3.435 ± 0.057	4.922GlyGly: 4.922 ± 0.096	1.04GlyHis: 1.04 ± 0.03	5.688GlyIle: 5.688 ± 0.062	5.78GlyLys: 5.78 ± 0.072	5.808GlyLeu: 5.808 ± 0.07	1.518GlyMet: 1.518 ± 0.034	4.117GlyAsn: 4.117 ± 0.074	1.773GlyPro: 1.773 ± 0.04	2.023GlyGln: 2.023 ± 0.042	2.338GlyArg: 2.338 ± 0.04	4.587GlySer: 4.587 ± 0.088	4.352GlyThr: 4.352 ± 0.122	4.183GlyVal: 4.183 ± 0.059	0.759GlyTrp: 0.759 ± 0.021	2.936GlyTyr: 2.936 ± 0.047	0.0GlyXaa: 0.0 ± 0.0
His	0.89HisAla: 0.89 ± 0.026	0.203HisCys: 0.203 ± 0.011	0.807HisAsp: 0.807 ± 0.022	0.948HisGlu: 0.948 ± 0.025	1.059HisPhe: 1.059 ± 0.028	1.04HisGly: 1.04 ± 0.029	0.421HisHis: 0.421 ± 0.016	1.258HisIle: 1.258 ± 0.03	1.134HisLys: 1.134 ± 0.028	1.751HisLeu: 1.751 ± 0.039	0.325HisMet: 0.325 ± 0.015	0.863HisAsn: 0.863 ± 0.022	0.886HisPro: 0.886 ± 0.025	0.616HisGln: 0.616 ± 0.02	0.625HisArg: 0.625 ± 0.022	1.143HisSer: 1.143 ± 0.027	0.822HisThr: 0.822 ± 0.021	0.865HisVal: 0.865 ± 0.022	0.227HisTrp: 0.227 ± 0.011	0.799HisTyr: 0.799 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	5.15IleAla: 5.15 ± 0.058	0.831IleCys: 0.831 ± 0.03	4.392IleAsp: 4.392 ± 0.061	5.222IleGlu: 5.222 ± 0.065	4.023IlePhe: 4.023 ± 0.068	4.908IleGly: 4.908 ± 0.063	1.447IleHis: 1.447 ± 0.031	6.21IleIle: 6.21 ± 0.077	6.322IleLys: 6.322 ± 0.067	7.113IleLeu: 7.113 ± 0.076	1.401IleMet: 1.401 ± 0.031	4.922IleAsn: 4.922 ± 0.058	3.413IlePro: 3.413 ± 0.05	2.517IleGln: 2.517 ± 0.039	2.912IleArg: 2.912 ± 0.05	6.303IleSer: 6.303 ± 0.064	4.816IleThr: 4.816 ± 0.073	4.741IleVal: 4.741 ± 0.064	0.727IleTrp: 0.727 ± 0.023	3.214IleTyr: 3.214 ± 0.05	0.0IleXaa: 0.0 ± 0.0
Lys	5.133LysAla: 5.133 ± 0.072	0.463LysCys: 0.463 ± 0.017	4.851LysAsp: 4.851 ± 0.059	6.326LysGlu: 6.326 ± 0.105	3.208LysPhe: 3.208 ± 0.055	5.019LysGly: 5.019 ± 0.053	1.164LysHis: 1.164 ± 0.03	6.582LysIle: 6.582 ± 0.076	6.597LysLys: 6.597 ± 0.109	6.705LysLeu: 6.705 ± 0.082	1.865LysMet: 1.865 ± 0.04	4.983LysAsn: 4.983 ± 0.063	2.51LysPro: 2.51 ± 0.041	2.319LysGln: 2.319 ± 0.04	2.844LysArg: 2.844 ± 0.056	5.01LysSer: 5.01 ± 0.069	4.106LysThr: 4.106 ± 0.055	5.281LysVal: 5.281 ± 0.065	0.827LysTrp: 0.827 ± 0.024	3.114LysTyr: 3.114 ± 0.048	0.0LysXaa: 0.0 ± 0.0
Leu	5.455LeuAla: 5.455 ± 0.061	0.839LeuCys: 0.839 ± 0.024	4.567LeuAsp: 4.567 ± 0.057	5.481LeuGlu: 5.481 ± 0.076	4.939LeuPhe: 4.939 ± 0.074	5.467LeuGly: 5.467 ± 0.073	1.502LeuHis: 1.502 ± 0.034	7.348LeuIle: 7.348 ± 0.085	8.101LeuLys: 8.101 ± 0.101	8.573LeuLeu: 8.573 ± 0.109	1.93LeuMet: 1.93 ± 0.038	5.944LeuAsn: 5.944 ± 0.058	3.781LeuPro: 3.781 ± 0.055	2.833LeuGln: 2.833 ± 0.042	3.339LeuArg: 3.339 ± 0.049	7.388LeuSer: 7.388 ± 0.073	5.328LeuThr: 5.328 ± 0.08	5.103LeuVal: 5.103 ± 0.059	0.875LeuTrp: 0.875 ± 0.024	3.477LeuTyr: 3.477 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	1.484MetAla: 1.484 ± 0.036	0.144MetCys: 0.144 ± 0.009	1.144MetAsp: 1.144 ± 0.027	1.406MetGlu: 1.406 ± 0.027	0.822MetPhe: 0.822 ± 0.027	1.305MetGly: 1.305 ± 0.028	0.364MetHis: 0.364 ± 0.016	1.595MetIle: 1.595 ± 0.036	1.981MetLys: 1.981 ± 0.034	1.847MetLeu: 1.847 ± 0.036	0.481MetMet: 0.481 ± 0.018	1.26MetAsn: 1.26 ± 0.026	0.845MetPro: 0.845 ± 0.024	0.66MetGln: 0.66 ± 0.021	0.804MetArg: 0.804 ± 0.024	1.279MetSer: 1.279 ± 0.026	1.039MetThr: 1.039 ± 0.026	1.315MetVal: 1.315 ± 0.026	0.165MetTrp: 0.165 ± 0.012	0.64MetTyr: 0.64 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.712AsnAla: 3.712 ± 0.086	0.553AsnCys: 0.553 ± 0.022	2.934AsnAsp: 2.934 ± 0.052	3.493AsnGlu: 3.493 ± 0.051	3.044AsnPhe: 3.044 ± 0.05	4.338AsnGly: 4.338 ± 0.094	1.003AsnHis: 1.003 ± 0.025	4.855AsnIle: 4.855 ± 0.061	4.553AsnLys: 4.553 ± 0.065	5.453AsnLeu: 5.453 ± 0.066	1.133AsnMet: 1.133 ± 0.025	3.874AsnAsn: 3.874 ± 0.079	2.837AsnPro: 2.837 ± 0.049	2.015AsnGln: 2.015 ± 0.035	2.044AsnArg: 2.044 ± 0.037	4.103AsnSer: 4.103 ± 0.063	3.279AsnThr: 3.279 ± 0.06	3.314AsnVal: 3.314 ± 0.05	0.719AsnTrp: 0.719 ± 0.019	2.731AsnTyr: 2.731 ± 0.045	0.0AsnXaa: 0.0 ± 0.0
Pro	2.481ProAla: 2.481 ± 0.052	0.28ProCys: 0.28 ± 0.014	2.392ProAsp: 2.392 ± 0.043	3.022ProGlu: 3.022 ± 0.049	1.991ProPhe: 1.991 ± 0.037	2.64ProGly: 2.64 ± 0.051	0.632ProHis: 0.632 ± 0.021	2.386ProIle: 2.386 ± 0.041	2.161ProLys: 2.161 ± 0.038	3.229ProLeu: 3.229 ± 0.051	0.65ProMet: 0.65 ± 0.022	2.017ProAsn: 2.017 ± 0.042	1.026ProPro: 1.026 ± 0.028	1.157ProGln: 1.157 ± 0.025	0.932ProArg: 0.932 ± 0.024	2.788ProSer: 2.788 ± 0.06	1.774ProThr: 1.774 ± 0.047	3.083ProVal: 3.083 ± 0.054	0.334ProTrp: 0.334 ± 0.015	1.557ProTyr: 1.557 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	1.895GlnAla: 1.895 ± 0.034	0.196GlnCys: 0.196 ± 0.011	1.517GlnAsp: 1.517 ± 0.03	2.111GlnGlu: 2.111 ± 0.047	1.448GlnPhe: 1.448 ± 0.031	1.819GlnGly: 1.819 ± 0.035	0.479GlnHis: 0.479 ± 0.018	2.461GlnIle: 2.461 ± 0.049	2.76GlnLys: 2.76 ± 0.042	3.079GlnLeu: 3.079 ± 0.051	0.767GlnMet: 0.767 ± 0.025	1.947GlnAsn: 1.947 ± 0.039	0.989GlnPro: 0.989 ± 0.027	1.133GlnGln: 1.133 ± 0.033	1.228GlnArg: 1.228 ± 0.032	1.998GlnSer: 1.998 ± 0.032	1.77GlnThr: 1.77 ± 0.037	1.849GlnVal: 1.849 ± 0.034	0.415GlnTrp: 0.415 ± 0.016	1.372GlnTyr: 1.372 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	1.959ArgAla: 1.959 ± 0.038	0.249ArgCys: 0.249 ± 0.013	1.721ArgAsp: 1.721 ± 0.029	2.354ArgGlu: 2.354 ± 0.052	1.957ArgPhe: 1.957 ± 0.041	1.893ArgGly: 1.893 ± 0.036	0.594ArgHis: 0.594 ± 0.022	3.214ArgIle: 3.214 ± 0.043	3.078ArgLys: 3.078 ± 0.054	3.49ArgLeu: 3.49 ± 0.059	0.889ArgMet: 0.889 ± 0.024	2.261ArgAsn: 2.261 ± 0.038	1.143ArgPro: 1.143 ± 0.03	1.125ArgGln: 1.125 ± 0.028	1.364ArgArg: 1.364 ± 0.032	2.148ArgSer: 2.148 ± 0.04	1.858ArgThr: 1.858 ± 0.037	2.105ArgVal: 2.105 ± 0.037	0.404ArgTrp: 0.404 ± 0.015	1.584ArgTyr: 1.584 ± 0.034	0.0ArgXaa: 0.0 ± 0.0
Ser	4.171SerAla: 4.171 ± 0.066	0.729SerCys: 0.729 ± 0.022	3.933SerAsp: 3.933 ± 0.052	4.428SerGlu: 4.428 ± 0.063	4.178SerPhe: 4.178 ± 0.055	5.93SerGly: 5.93 ± 0.106	1.063SerHis: 1.063 ± 0.027	5.688SerIle: 5.688 ± 0.058	4.989SerLys: 4.989 ± 0.063	6.738SerLeu: 6.738 ± 0.073	1.35SerMet: 1.35 ± 0.028	3.852SerAsn: 3.852 ± 0.066	2.556SerPro: 2.556 ± 0.045	2.14SerGln: 2.14 ± 0.037	2.434SerArg: 2.434 ± 0.04	5.366SerSer: 5.366 ± 0.084	3.743SerThr: 3.743 ± 0.07	4.655SerVal: 4.655 ± 0.074	0.741SerTrp: 0.741 ± 0.022	3.069SerTyr: 3.069 ± 0.052	0.0SerXaa: 0.0 ± 0.0
Thr	3.64ThrAla: 3.64 ± 0.08	0.462ThrCys: 0.462 ± 0.02	3.152ThrAsp: 3.152 ± 0.06	3.197ThrGlu: 3.197 ± 0.046	2.938ThrPhe: 2.938 ± 0.048	4.649ThrGly: 4.649 ± 0.1	0.828ThrHis: 0.828 ± 0.022	4.713ThrIle: 4.713 ± 0.064	3.345ThrLys: 3.345 ± 0.053	5.156ThrLeu: 5.156 ± 0.074	0.862ThrMet: 0.862 ± 0.024	2.87ThrAsn: 2.87 ± 0.063	2.43ThrPro: 2.43 ± 0.063	1.481ThrGln: 1.481 ± 0.033	1.616ThrArg: 1.616 ± 0.031	4.157ThrSer: 4.157 ± 0.09	3.274ThrThr: 3.274 ± 0.09	3.722ThrVal: 3.722 ± 0.083	0.623ThrTrp: 0.623 ± 0.024	2.421ThrTyr: 2.421 ± 0.049	0.0ThrXaa: 0.0 ± 0.0
Val	3.714ValAla: 3.714 ± 0.057	0.632ValCys: 0.632 ± 0.028	2.963ValAsp: 2.963 ± 0.046	3.616ValGlu: 3.616 ± 0.05	3.213ValPhe: 3.213 ± 0.05	3.411ValGly: 3.411 ± 0.053	1.006ValHis: 1.006 ± 0.024	4.937ValIle: 4.937 ± 0.054	5.14ValLys: 5.14 ± 0.065	5.663ValLeu: 5.663 ± 0.064	1.24ValMet: 1.24 ± 0.029	3.744ValAsn: 3.744 ± 0.065	2.351ValPro: 2.351 ± 0.039	1.77ValGln: 1.77 ± 0.035	2.235ValArg: 2.235 ± 0.036	4.714ValSer: 4.714 ± 0.072	3.768ValThr: 3.768 ± 0.096	3.963ValVal: 3.963 ± 0.06	0.592ValTrp: 0.592 ± 0.018	2.546ValTyr: 2.546 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	0.573TrpAla: 0.573 ± 0.019	0.093TrpCys: 0.093 ± 0.007	0.608TrpAsp: 0.608 ± 0.019	0.625TrpGlu: 0.625 ± 0.019	0.508TrpPhe: 0.508 ± 0.018	0.718TrpGly: 0.718 ± 0.023	0.206TrpHis: 0.206 ± 0.012	0.79TrpIle: 0.79 ± 0.025	0.89TrpLys: 0.89 ± 0.025	0.899TrpLeu: 0.899 ± 0.025	0.278TrpMet: 0.278 ± 0.014	0.7TrpAsn: 0.7 ± 0.024	0.293TrpPro: 0.293 ± 0.012	0.402TrpGln: 0.402 ± 0.016	0.399TrpArg: 0.399 ± 0.015	0.773TrpSer: 0.773 ± 0.032	0.676TrpThr: 0.676 ± 0.027	0.594TrpVal: 0.594 ± 0.017	0.14TrpTrp: 0.14 ± 0.009	0.466TrpTyr: 0.466 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.257TyrAla: 2.257 ± 0.041	0.421TyrCys: 0.421 ± 0.016	2.23TyrAsp: 2.23 ± 0.043	2.289TyrGlu: 2.289 ± 0.044	2.606TyrPhe: 2.606 ± 0.042	2.533TyrGly: 2.533 ± 0.047	0.817TyrHis: 0.817 ± 0.023	3.071TyrIle: 3.071 ± 0.042	3.244TyrLys: 3.244 ± 0.046	4.012TyrLeu: 4.012 ± 0.049	0.748TyrMet: 0.748 ± 0.022	2.721TyrAsn: 2.721 ± 0.047	1.657TyrPro: 1.657 ± 0.034	1.453TyrGln: 1.453 ± 0.031	1.652TyrArg: 1.652 ± 0.032	3.375TyrSer: 3.375 ± 0.052	2.463TyrThr: 2.463 ± 0.053	2.13TyrVal: 2.13 ± 0.037	0.5TyrTrp: 0.5 ± 0.018	2.249TyrTyr: 2.249 ± 0.051	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5042 proteins (1718912 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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