Amino acid dipepetide frequency for Salinibacillus xinjiangensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.765AlaAla: 4.765 ± 0.089	0.52AlaCys: 0.52 ± 0.025	3.066AlaAsp: 3.066 ± 0.049	4.422AlaGlu: 4.422 ± 0.076	3.078AlaPhe: 3.078 ± 0.053	4.76AlaGly: 4.76 ± 0.074	1.166AlaHis: 1.166 ± 0.035	5.6AlaIle: 5.6 ± 0.085	4.648AlaLys: 4.648 ± 0.069	6.486AlaLeu: 6.486 ± 0.09	1.91AlaMet: 1.91 ± 0.043	2.864AlaAsn: 2.864 ± 0.057	1.914AlaPro: 1.914 ± 0.044	2.147AlaGln: 2.147 ± 0.05	2.396AlaArg: 2.396 ± 0.044	3.766AlaSer: 3.766 ± 0.062	3.346AlaThr: 3.346 ± 0.063	4.808AlaVal: 4.808 ± 0.08	0.551AlaTrp: 0.551 ± 0.026	2.092AlaTyr: 2.092 ± 0.044	0.0AlaXaa: 0.0 ± 0.0
Cys	0.354CysAla: 0.354 ± 0.021	0.074CysCys: 0.074 ± 0.009	0.353CysAsp: 0.353 ± 0.019	0.423CysGlu: 0.423 ± 0.021	0.278CysPhe: 0.278 ± 0.016	0.592CysGly: 0.592 ± 0.027	0.192CysHis: 0.192 ± 0.014	0.454CysIle: 0.454 ± 0.022	0.339CysLys: 0.339 ± 0.019	0.564CysLeu: 0.564 ± 0.026	0.183CysMet: 0.183 ± 0.012	0.234CysAsn: 0.234 ± 0.017	0.307CysPro: 0.307 ± 0.019	0.25CysGln: 0.25 ± 0.014	0.228CysArg: 0.228 ± 0.016	0.428CysSer: 0.428 ± 0.02	0.333CysThr: 0.333 ± 0.019	0.388CysVal: 0.388 ± 0.021	0.049CysTrp: 0.049 ± 0.006	0.234CysTyr: 0.234 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	3.175AspAla: 3.175 ± 0.061	0.34AspCys: 0.34 ± 0.017	2.843AspAsp: 2.843 ± 0.058	5.053AspGlu: 5.053 ± 0.082	2.467AspPhe: 2.467 ± 0.051	3.412AspGly: 3.412 ± 0.067	1.307AspHis: 1.307 ± 0.041	4.332AspIle: 4.332 ± 0.074	3.093AspLys: 3.093 ± 0.054	5.158AspLeu: 5.158 ± 0.07	1.452AspMet: 1.452 ± 0.035	1.87AspAsn: 1.87 ± 0.056	2.034AspPro: 2.034 ± 0.049	2.678AspGln: 2.678 ± 0.058	2.237AspArg: 2.237 ± 0.042	2.651AspSer: 2.651 ± 0.061	2.564AspThr: 2.564 ± 0.053	4.176AspVal: 4.176 ± 0.058	0.675AspTrp: 0.675 ± 0.026	2.28AspTyr: 2.28 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	4.912GluAla: 4.912 ± 0.069	0.336GluCys: 0.336 ± 0.017	4.532GluAsp: 4.532 ± 0.079	7.788GluGlu: 7.788 ± 0.116	2.68GluPhe: 2.68 ± 0.054	4.649GluGly: 4.649 ± 0.07	1.69GluHis: 1.69 ± 0.04	5.512GluIle: 5.512 ± 0.074	6.741GluLys: 6.741 ± 0.09	7.117GluLeu: 7.117 ± 0.091	2.375GluMet: 2.375 ± 0.046	4.112GluAsn: 4.112 ± 0.075	2.125GluPro: 2.125 ± 0.049	3.904GluGln: 3.904 ± 0.068	3.496GluArg: 3.496 ± 0.059	3.951GluSer: 3.951 ± 0.071	3.94GluThr: 3.94 ± 0.057	5.63GluVal: 5.63 ± 0.078	0.905GluTrp: 0.905 ± 0.029	2.326GluTyr: 2.326 ± 0.053	0.0GluXaa: 0.0 ± 0.0
Phe	2.832PheAla: 2.832 ± 0.054	0.324PheCys: 0.324 ± 0.018	2.447PheAsp: 2.447 ± 0.049	3.018PheGlu: 3.018 ± 0.053	2.282PhePhe: 2.282 ± 0.061	3.342PheGly: 3.342 ± 0.057	1.087PheHis: 1.087 ± 0.032	3.911PheIle: 3.911 ± 0.077	2.368PheLys: 2.368 ± 0.053	4.441PheLeu: 4.441 ± 0.069	1.254PheMet: 1.254 ± 0.035	1.891PheAsn: 1.891 ± 0.043	1.666PhePro: 1.666 ± 0.042	1.893PheGln: 1.893 ± 0.044	1.563PheArg: 1.563 ± 0.039	3.173PheSer: 3.173 ± 0.056	2.61PheThr: 2.61 ± 0.048	3.235PheVal: 3.235 ± 0.068	0.458PheTrp: 0.458 ± 0.022	1.728PheTyr: 1.728 ± 0.044	0.0PheXaa: 0.0 ± 0.0
Gly	4.692GlyAla: 4.692 ± 0.095	0.518GlyCys: 0.518 ± 0.024	3.433GlyAsp: 3.433 ± 0.063	4.763GlyGlu: 4.763 ± 0.083	3.427GlyPhe: 3.427 ± 0.067	4.796GlyGly: 4.796 ± 0.096	1.506GlyHis: 1.506 ± 0.045	5.818GlyIle: 5.818 ± 0.092	4.854GlyLys: 4.854 ± 0.076	6.619GlyLeu: 6.619 ± 0.097	2.161GlyMet: 2.161 ± 0.052	2.757GlyAsn: 2.757 ± 0.059	1.819GlyPro: 1.819 ± 0.046	2.317GlyGln: 2.317 ± 0.048	2.525GlyArg: 2.525 ± 0.057	3.85GlySer: 3.85 ± 0.064	3.932GlyThr: 3.932 ± 0.062	5.104GlyVal: 5.104 ± 0.077	0.75GlyTrp: 0.75 ± 0.031	2.784GlyTyr: 2.784 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	1.252HisAla: 1.252 ± 0.036	0.181HisCys: 0.181 ± 0.016	1.129HisAsp: 1.129 ± 0.031	1.515HisGlu: 1.515 ± 0.037	1.071HisPhe: 1.071 ± 0.03	1.426HisGly: 1.426 ± 0.04	0.714HisHis: 0.714 ± 0.027	1.582HisIle: 1.582 ± 0.043	1.252HisLys: 1.252 ± 0.037	2.237HisLeu: 2.237 ± 0.042	0.525HisMet: 0.525 ± 0.024	0.92HisAsn: 0.92 ± 0.034	1.137HisPro: 1.137 ± 0.034	1.041HisGln: 1.041 ± 0.032	0.891HisArg: 0.891 ± 0.026	1.243HisSer: 1.243 ± 0.038	1.089HisThr: 1.089 ± 0.033	1.522HisVal: 1.522 ± 0.038	0.241HisTrp: 0.241 ± 0.016	0.896HisTyr: 0.896 ± 0.032	0.0HisXaa: 0.0 ± 0.0
Ile	5.548IleAla: 5.548 ± 0.091	0.536IleCys: 0.536 ± 0.024	4.377IleAsp: 4.377 ± 0.062	5.684IleGlu: 5.684 ± 0.08	3.422IlePhe: 3.422 ± 0.069	5.972IleGly: 5.972 ± 0.094	1.76IleHis: 1.76 ± 0.039	5.656IleIle: 5.656 ± 0.084	4.398IleLys: 4.398 ± 0.064	7.184IleLeu: 7.184 ± 0.104	1.829IleMet: 1.829 ± 0.04	3.198IleAsn: 3.198 ± 0.058	3.5IlePro: 3.5 ± 0.064	3.362IleGln: 3.362 ± 0.069	2.936IleArg: 2.936 ± 0.048	5.021IleSer: 5.021 ± 0.074	4.346IleThr: 4.346 ± 0.063	5.433IleVal: 5.433 ± 0.087	0.655IleTrp: 0.655 ± 0.027	2.553IleTyr: 2.553 ± 0.049	0.0IleXaa: 0.0 ± 0.0
Lys	4.262LysAla: 4.262 ± 0.063	0.289LysCys: 0.289 ± 0.017	4.012LysAsp: 4.012 ± 0.072	6.954LysGlu: 6.954 ± 0.101	1.987LysPhe: 1.987 ± 0.042	4.547LysGly: 4.547 ± 0.072	1.452LysHis: 1.452 ± 0.039	4.367LysIle: 4.367 ± 0.068	5.608LysLys: 5.608 ± 0.103	5.739LysLeu: 5.739 ± 0.083	2.103LysMet: 2.103 ± 0.045	3.296LysAsn: 3.296 ± 0.054	2.318LysPro: 2.318 ± 0.044	3.385LysGln: 3.385 ± 0.061	3.297LysArg: 3.297 ± 0.062	3.621LysSer: 3.621 ± 0.067	3.496LysThr: 3.496 ± 0.067	4.897LysVal: 4.897 ± 0.063	0.79LysTrp: 0.79 ± 0.028	2.159LysTyr: 2.159 ± 0.047	0.0LysXaa: 0.0 ± 0.0
Leu	6.619LeuAla: 6.619 ± 0.089	0.588LeuCys: 0.588 ± 0.025	4.886LeuAsp: 4.886 ± 0.078	6.779LeuGlu: 6.779 ± 0.09	4.871LeuPhe: 4.871 ± 0.083	6.498LeuGly: 6.498 ± 0.093	2.053LeuHis: 2.053 ± 0.045	7.099LeuIle: 7.099 ± 0.115	6.561LeuLys: 6.561 ± 0.093	9.41LeuLeu: 9.41 ± 0.131	2.518LeuMet: 2.518 ± 0.051	4.375LeuAsn: 4.375 ± 0.075	3.77LeuPro: 3.77 ± 0.061	3.654LeuGln: 3.654 ± 0.057	3.453LeuArg: 3.453 ± 0.06	6.625LeuSer: 6.625 ± 0.087	5.498LeuThr: 5.498 ± 0.069	6.215LeuVal: 6.215 ± 0.086	0.863LeuTrp: 0.863 ± 0.032	3.089LeuTyr: 3.089 ± 0.063	0.001LeuXaa: 0.001 ± 0.001
Met	1.944MetAla: 1.944 ± 0.045	0.139MetCys: 0.139 ± 0.012	1.664MetAsp: 1.664 ± 0.042	2.077MetGlu: 2.077 ± 0.044	1.12MetPhe: 1.12 ± 0.035	1.915MetGly: 1.915 ± 0.048	0.388MetHis: 0.388 ± 0.019	2.175MetIle: 2.175 ± 0.048	2.493MetLys: 2.493 ± 0.055	2.486MetLeu: 2.486 ± 0.046	0.884MetMet: 0.884 ± 0.034	1.59MetAsn: 1.59 ± 0.041	0.945MetPro: 0.945 ± 0.029	0.91MetGln: 0.91 ± 0.028	1.052MetArg: 1.052 ± 0.033	1.748MetSer: 1.748 ± 0.039	1.634MetThr: 1.634 ± 0.039	1.948MetVal: 1.948 ± 0.046	0.187MetTrp: 0.187 ± 0.014	0.771MetTyr: 0.771 ± 0.028	0.0MetXaa: 0.0 ± 0.0
Asn	2.552AsnAla: 2.552 ± 0.045	0.298AsnCys: 0.298 ± 0.017	2.321AsnAsp: 2.321 ± 0.051	3.834AsnGlu: 3.834 ± 0.061	1.677AsnPhe: 1.677 ± 0.043	3.183AsnGly: 3.183 ± 0.065	1.253AsnHis: 1.253 ± 0.038	3.423AsnIle: 3.423 ± 0.061	2.89AsnLys: 2.89 ± 0.054	3.929AsnLeu: 3.929 ± 0.063	1.267AsnMet: 1.267 ± 0.035	1.959AsnAsn: 1.959 ± 0.05	2.229AsnPro: 2.229 ± 0.048	2.619AsnGln: 2.619 ± 0.07	2.156AsnArg: 2.156 ± 0.051	2.32AsnSer: 2.32 ± 0.05	2.198AsnThr: 2.198 ± 0.045	3.097AsnVal: 3.097 ± 0.056	0.567AsnTrp: 0.567 ± 0.026	1.508AsnTyr: 1.508 ± 0.037	0.0AsnXaa: 0.0 ± 0.0
Pro	1.986ProAla: 1.986 ± 0.047	0.168ProCys: 0.168 ± 0.014	2.112ProAsp: 2.112 ± 0.041	3.08ProGlu: 3.08 ± 0.054	1.978ProPhe: 1.978 ± 0.043	2.314ProGly: 2.314 ± 0.052	0.837ProHis: 0.837 ± 0.028	2.953ProIle: 2.953 ± 0.057	2.347ProLys: 2.347 ± 0.053	3.322ProLeu: 3.322 ± 0.053	0.865ProMet: 0.865 ± 0.028	1.842ProAsn: 1.842 ± 0.041	1.001ProPro: 1.001 ± 0.033	1.159ProGln: 1.159 ± 0.034	1.1ProArg: 1.1 ± 0.034	2.341ProSer: 2.341 ± 0.044	2.007ProThr: 2.007 ± 0.047	2.828ProVal: 2.828 ± 0.058	0.374ProTrp: 0.374 ± 0.022	1.433ProTyr: 1.433 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	2.91GlnAla: 2.91 ± 0.053	0.182GlnCys: 0.182 ± 0.013	2.051GlnAsp: 2.051 ± 0.047	3.35GlnGlu: 3.35 ± 0.061	1.848GlnPhe: 1.848 ± 0.048	2.341GlnGly: 2.341 ± 0.054	0.846GlnHis: 0.846 ± 0.029	2.91GlnIle: 2.91 ± 0.058	3.184GlnLys: 3.184 ± 0.062	4.215GlnLeu: 4.215 ± 0.074	1.301GlnMet: 1.301 ± 0.038	2.023GlnAsn: 2.023 ± 0.051	1.303GlnPro: 1.303 ± 0.035	2.185GlnGln: 2.185 ± 0.066	1.498GlnArg: 1.498 ± 0.042	2.536GlnSer: 2.536 ± 0.055	2.195GlnThr: 2.195 ± 0.048	2.709GlnVal: 2.709 ± 0.054	0.455GlnTrp: 0.455 ± 0.022	1.48GlnTyr: 1.48 ± 0.04	0.0GlnXaa: 0.0 ± 0.0
Arg	2.225ArgAla: 2.225 ± 0.044	0.19ArgCys: 0.19 ± 0.014	2.068ArgAsp: 2.068 ± 0.044	3.223ArgGlu: 3.223 ± 0.057	1.88ArgPhe: 1.88 ± 0.048	2.27ArgGly: 2.27 ± 0.044	0.788ArgHis: 0.788 ± 0.027	2.961ArgIle: 2.961 ± 0.057	3.182ArgLys: 3.182 ± 0.059	3.849ArgLeu: 3.849 ± 0.07	1.242ArgMet: 1.242 ± 0.04	1.924ArgAsn: 1.924 ± 0.041	1.281ArgPro: 1.281 ± 0.036	1.491ArgGln: 1.491 ± 0.039	1.735ArgArg: 1.735 ± 0.044	2.072ArgSer: 2.072 ± 0.042	1.961ArgThr: 1.961 ± 0.051	2.712ArgVal: 2.712 ± 0.054	0.394ArgTrp: 0.394 ± 0.02	1.512ArgTyr: 1.512 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	3.418SerAla: 3.418 ± 0.054	0.348SerCys: 0.348 ± 0.019	2.963SerAsp: 2.963 ± 0.053	4.141SerGlu: 4.141 ± 0.072	3.33SerPhe: 3.33 ± 0.064	4.277SerGly: 4.277 ± 0.073	1.221SerHis: 1.221 ± 0.037	5.077SerIle: 5.077 ± 0.071	3.844SerLys: 3.844 ± 0.061	6.036SerLeu: 6.036 ± 0.077	1.723SerMet: 1.723 ± 0.041	2.703SerAsn: 2.703 ± 0.054	2.103SerPro: 2.103 ± 0.045	2.148SerGln: 2.148 ± 0.052	2.158SerArg: 2.158 ± 0.046	3.948SerSer: 3.948 ± 0.065	3.241SerThr: 3.241 ± 0.059	4.157SerVal: 4.157 ± 0.065	0.607SerTrp: 0.607 ± 0.025	2.261SerTyr: 2.261 ± 0.051	0.0SerXaa: 0.0 ± 0.0
Thr	3.578ThrAla: 3.578 ± 0.066	0.334ThrCys: 0.334 ± 0.018	2.786ThrAsp: 2.786 ± 0.057	3.74ThrGlu: 3.74 ± 0.062	2.673ThrPhe: 2.673 ± 0.05	4.021ThrGly: 4.021 ± 0.061	1.054ThrHis: 1.054 ± 0.031	4.543ThrIle: 4.543 ± 0.06	3.379ThrLys: 3.379 ± 0.06	5.29ThrLeu: 5.29 ± 0.075	1.274ThrMet: 1.274 ± 0.029	2.508ThrAsn: 2.508 ± 0.054	2.265ThrPro: 2.265 ± 0.05	1.553ThrGln: 1.553 ± 0.039	1.741ThrArg: 1.741 ± 0.038	3.346ThrSer: 3.346 ± 0.06	2.996ThrThr: 2.996 ± 0.058	3.914ThrVal: 3.914 ± 0.074	0.546ThrTrp: 0.546 ± 0.02	2.032ThrTyr: 2.032 ± 0.041	0.001ThrXaa: 0.001 ± 0.001
Val	4.758ValAla: 4.758 ± 0.07	0.548ValCys: 0.548 ± 0.023	4.147ValAsp: 4.147 ± 0.072	5.492ValGlu: 5.492 ± 0.074	3.051ValPhe: 3.051 ± 0.054	4.791ValGly: 4.791 ± 0.077	1.398ValHis: 1.398 ± 0.035	5.674ValIle: 5.674 ± 0.084	4.742ValLys: 4.742 ± 0.063	6.761ValLeu: 6.761 ± 0.089	1.948ValMet: 1.948 ± 0.041	3.243ValAsn: 3.243 ± 0.058	2.636ValPro: 2.636 ± 0.056	2.674ValGln: 2.674 ± 0.059	2.574ValArg: 2.574 ± 0.05	4.463ValSer: 4.463 ± 0.075	3.957ValThr: 3.957 ± 0.064	5.293ValVal: 5.293 ± 0.09	0.614ValTrp: 0.614 ± 0.022	2.353ValTyr: 2.353 ± 0.047	0.001ValXaa: 0.001 ± 0.001
Trp	0.588TrpAla: 0.588 ± 0.027	0.071TrpCys: 0.071 ± 0.009	0.507TrpAsp: 0.507 ± 0.023	0.691TrpGlu: 0.691 ± 0.026	0.536TrpPhe: 0.536 ± 0.021	0.739TrpGly: 0.739 ± 0.027	0.212TrpHis: 0.212 ± 0.02	0.864TrpIle: 0.864 ± 0.031	0.716TrpLys: 0.716 ± 0.028	1.158TrpLeu: 1.158 ± 0.034	0.329TrpMet: 0.329 ± 0.019	0.527TrpAsn: 0.527 ± 0.021	0.254TrpPro: 0.254 ± 0.016	0.381TrpGln: 0.381 ± 0.02	0.392TrpArg: 0.392 ± 0.019	0.573TrpSer: 0.573 ± 0.022	0.481TrpThr: 0.481 ± 0.021	0.701TrpVal: 0.701 ± 0.03	0.175TrpTrp: 0.175 ± 0.014	0.338TrpTyr: 0.338 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.936TyrAla: 1.936 ± 0.044	0.272TyrCys: 0.272 ± 0.016	2.1TyrAsp: 2.1 ± 0.047	2.697TyrGlu: 2.697 ± 0.052	1.865TyrPhe: 1.865 ± 0.043	2.581TyrGly: 2.581 ± 0.058	0.94TyrHis: 0.94 ± 0.031	2.457TyrIle: 2.457 ± 0.049	1.937TyrLys: 1.937 ± 0.049	3.426TyrLeu: 3.426 ± 0.068	0.925TyrMet: 0.925 ± 0.034	1.445TyrAsn: 1.445 ± 0.037	1.439TyrPro: 1.439 ± 0.046	1.771TyrGln: 1.771 ± 0.043	1.531TyrArg: 1.531 ± 0.039	2.03TyrSer: 2.03 ± 0.046	1.749TyrThr: 1.749 ± 0.037	2.348TyrVal: 2.348 ± 0.042	0.379TyrTrp: 0.379 ± 0.021	1.395TyrTyr: 1.395 ± 0.041	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.001	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.001XaaPhe: 0.001 ± 0.001	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.001	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3701 proteins (1049479 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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