Amino acid dipepetide frequency for Tenacibaculum soleae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.72AlaAla: 3.72 ± 0.09	0.526AlaCys: 0.526 ± 0.027	3.136AlaAsp: 3.136 ± 0.067	3.458AlaGlu: 3.458 ± 0.076	3.118AlaPhe: 3.118 ± 0.058	3.781AlaGly: 3.781 ± 0.074	1.023AlaHis: 1.023 ± 0.034	5.621AlaIle: 5.621 ± 0.105	5.411AlaLys: 5.411 ± 0.087	5.754AlaLeu: 5.754 ± 0.09	1.4AlaMet: 1.4 ± 0.047	3.549AlaAsn: 3.549 ± 0.065	1.759AlaPro: 1.759 ± 0.048	2.142AlaGln: 2.142 ± 0.046	1.78AlaArg: 1.78 ± 0.05	3.991AlaSer: 3.991 ± 0.074	3.862AlaThr: 3.862 ± 0.094	3.888AlaVal: 3.888 ± 0.071	0.495AlaTrp: 0.495 ± 0.026	2.247AlaTyr: 2.247 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	0.433CysAla: 0.433 ± 0.024	0.094CysCys: 0.094 ± 0.012	0.409CysAsp: 0.409 ± 0.023	0.409CysGlu: 0.409 ± 0.022	0.384CysPhe: 0.384 ± 0.019	0.58CysGly: 0.58 ± 0.026	0.166CysHis: 0.166 ± 0.018	0.571CysIle: 0.571 ± 0.028	0.545CysLys: 0.545 ± 0.028	0.556CysLeu: 0.556 ± 0.025	0.154CysMet: 0.154 ± 0.014	0.434CysAsn: 0.434 ± 0.023	0.283CysPro: 0.283 ± 0.022	0.174CysGln: 0.174 ± 0.013	0.162CysArg: 0.162 ± 0.013	0.504CysSer: 0.504 ± 0.029	0.366CysThr: 0.366 ± 0.025	0.424CysVal: 0.424 ± 0.021	0.057CysTrp: 0.057 ± 0.007	0.262CysTyr: 0.262 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	3.551AspAla: 3.551 ± 0.071	0.372AspCys: 0.372 ± 0.022	2.547AspAsp: 2.547 ± 0.059	3.716AspGlu: 3.716 ± 0.079	3.613AspPhe: 3.613 ± 0.06	3.177AspGly: 3.177 ± 0.069	0.661AspHis: 0.661 ± 0.026	4.427AspIle: 4.427 ± 0.082	4.758AspLys: 4.758 ± 0.077	4.839AspLeu: 4.839 ± 0.075	0.947AspMet: 0.947 ± 0.036	3.189AspAsn: 3.189 ± 0.066	1.199AspPro: 1.199 ± 0.043	1.048AspGln: 1.048 ± 0.037	1.495AspArg: 1.495 ± 0.04	2.764AspSer: 2.764 ± 0.063	2.711AspThr: 2.711 ± 0.057	3.758AspVal: 3.758 ± 0.096	0.612AspTrp: 0.612 ± 0.03	2.478AspTyr: 2.478 ± 0.064	0.0AspXaa: 0.0 ± 0.0
Glu	4.009GluAla: 4.009 ± 0.083	0.326GluCys: 0.326 ± 0.021	3.163GluAsp: 3.163 ± 0.06	4.642GluGlu: 4.642 ± 0.088	3.016GluPhe: 3.016 ± 0.063	3.354GluGly: 3.354 ± 0.067	1.05GluHis: 1.05 ± 0.035	5.709GluIle: 5.709 ± 0.089	6.52GluLys: 6.52 ± 0.098	6.22GluLeu: 6.22 ± 0.081	1.427GluMet: 1.427 ± 0.04	4.987GluAsn: 4.987 ± 0.072	1.265GluPro: 1.265 ± 0.038	2.168GluGln: 2.168 ± 0.05	2.248GluArg: 2.248 ± 0.053	2.95GluSer: 2.95 ± 0.061	3.65GluThr: 3.65 ± 0.066	4.223GluVal: 4.223 ± 0.071	0.514GluTrp: 0.514 ± 0.024	2.445GluTyr: 2.445 ± 0.047	0.0GluXaa: 0.0 ± 0.0
Phe	2.692PheAla: 2.692 ± 0.061	0.427PheCys: 0.427 ± 0.022	3.159PheAsp: 3.159 ± 0.05	3.133PheGlu: 3.133 ± 0.063	2.945PhePhe: 2.945 ± 0.079	3.563PheGly: 3.563 ± 0.065	0.767PheHis: 0.767 ± 0.033	4.464PheIle: 4.464 ± 0.082	4.63PheLys: 4.63 ± 0.077	5.025PheLeu: 5.025 ± 0.105	1.073PheMet: 1.073 ± 0.035	3.887PheAsn: 3.887 ± 0.092	1.479PhePro: 1.479 ± 0.042	1.384PheGln: 1.384 ± 0.037	1.43PheArg: 1.43 ± 0.043	4.197PheSer: 4.197 ± 0.071	3.257PheThr: 3.257 ± 0.067	2.973PheVal: 2.973 ± 0.064	0.577PheTrp: 0.577 ± 0.029	2.289PheTyr: 2.289 ± 0.058	0.0PheXaa: 0.0 ± 0.0
Gly	3.95GlyAla: 3.95 ± 0.071	0.535GlyCys: 0.535 ± 0.031	3.03GlyAsp: 3.03 ± 0.072	3.271GlyGlu: 3.271 ± 0.065	3.561GlyPhe: 3.561 ± 0.077	4.239GlyGly: 4.239 ± 0.09	0.996GlyHis: 0.996 ± 0.032	5.21GlyIle: 5.21 ± 0.084	5.453GlyLys: 5.453 ± 0.093	5.379GlyLeu: 5.379 ± 0.09	1.476GlyMet: 1.476 ± 0.043	3.599GlyAsn: 3.599 ± 0.077	1.079GlyPro: 1.079 ± 0.039	1.54GlyGln: 1.54 ± 0.041	1.889GlyArg: 1.889 ± 0.047	3.451GlySer: 3.451 ± 0.073	3.712GlyThr: 3.712 ± 0.073	4.443GlyVal: 4.443 ± 0.095	0.662GlyTrp: 0.662 ± 0.035	2.558GlyTyr: 2.558 ± 0.054	0.0GlyXaa: 0.0 ± 0.0
His	0.939HisAla: 0.939 ± 0.033	0.154HisCys: 0.154 ± 0.014	0.753HisAsp: 0.753 ± 0.033	0.9HisGlu: 0.9 ± 0.037	1.122HisPhe: 1.122 ± 0.04	0.896HisGly: 0.896 ± 0.034	0.468HisHis: 0.468 ± 0.024	1.445HisIle: 1.445 ± 0.046	1.426HisLys: 1.426 ± 0.039	1.688HisLeu: 1.688 ± 0.055	0.259HisMet: 0.259 ± 0.02	0.99HisAsn: 0.99 ± 0.031	0.846HisPro: 0.846 ± 0.034	0.813HisGln: 0.813 ± 0.036	0.582HisArg: 0.582 ± 0.03	0.962HisSer: 0.962 ± 0.031	0.978HisThr: 0.978 ± 0.035	0.836HisVal: 0.836 ± 0.033	0.182HisTrp: 0.182 ± 0.014	0.755HisTyr: 0.755 ± 0.031	0.0HisXaa: 0.0 ± 0.0
Ile	5.918IleAla: 5.918 ± 0.101	0.631IleCys: 0.631 ± 0.027	5.181IleAsp: 5.181 ± 0.076	5.772IleGlu: 5.772 ± 0.083	3.789IlePhe: 3.789 ± 0.081	5.189IleGly: 5.189 ± 0.088	1.412IleHis: 1.412 ± 0.043	6.963IleIle: 6.963 ± 0.108	7.392IleLys: 7.392 ± 0.097	7.136IleLeu: 7.136 ± 0.098	1.356IleMet: 1.356 ± 0.043	5.936IleAsn: 5.936 ± 0.11	3.188IlePro: 3.188 ± 0.068	2.7IleGln: 2.7 ± 0.054	2.459IleArg: 2.459 ± 0.053	5.787IleSer: 5.787 ± 0.097	5.552IleThr: 5.552 ± 0.084	4.846IleVal: 4.846 ± 0.074	0.679IleTrp: 0.679 ± 0.034	2.831IleTyr: 2.831 ± 0.062	0.0IleXaa: 0.0 ± 0.0
Lys	5.336LysAla: 5.336 ± 0.085	0.377LysCys: 0.377 ± 0.021	4.558LysAsp: 4.558 ± 0.076	7.738LysGlu: 7.738 ± 0.113	3.394LysPhe: 3.394 ± 0.064	5.213LysGly: 5.213 ± 0.079	1.702LysHis: 1.702 ± 0.04	7.895LysIle: 7.895 ± 0.107	9.753LysLys: 9.753 ± 0.133	7.561LysLeu: 7.561 ± 0.097	2.243LysMet: 2.243 ± 0.053	7.306LysAsn: 7.306 ± 0.108	2.477LysPro: 2.477 ± 0.055	3.268LysGln: 3.268 ± 0.067	3.18LysArg: 3.18 ± 0.061	5.148LysSer: 5.148 ± 0.083	5.801LysThr: 5.801 ± 0.09	5.452LysVal: 5.452 ± 0.083	0.806LysTrp: 0.806 ± 0.031	3.575LysTyr: 3.575 ± 0.069	0.0LysXaa: 0.0 ± 0.0
Leu	5.597LeuAla: 5.597 ± 0.102	0.541LeuCys: 0.541 ± 0.023	4.562LeuAsp: 4.562 ± 0.079	5.67LeuGlu: 5.67 ± 0.084	4.979LeuPhe: 4.979 ± 0.099	5.473LeuGly: 5.473 ± 0.097	1.553LeuHis: 1.553 ± 0.045	7.396LeuIle: 7.396 ± 0.113	8.924LeuLys: 8.924 ± 0.099	8.76LeuLeu: 8.76 ± 0.128	1.928LeuMet: 1.928 ± 0.048	6.202LeuAsn: 6.202 ± 0.1	3.282LeuPro: 3.282 ± 0.062	3.39LeuGln: 3.39 ± 0.075	2.869LeuArg: 2.869 ± 0.062	6.419LeuSer: 6.419 ± 0.099	5.295LeuThr: 5.295 ± 0.087	5.23LeuVal: 5.23 ± 0.082	0.722LeuTrp: 0.722 ± 0.031	3.045LeuTyr: 3.045 ± 0.059	0.0LeuXaa: 0.0 ± 0.0
Met	1.419MetAla: 1.419 ± 0.047	0.153MetCys: 0.153 ± 0.012	0.951MetAsp: 0.951 ± 0.037	1.058MetGlu: 1.058 ± 0.04	0.965MetPhe: 0.965 ± 0.068	1.175MetGly: 1.175 ± 0.04	0.369MetHis: 0.369 ± 0.02	1.575MetIle: 1.575 ± 0.048	2.186MetLys: 2.186 ± 0.048	1.952MetLeu: 1.952 ± 0.047	0.56MetMet: 0.56 ± 0.027	1.374MetAsn: 1.374 ± 0.037	0.749MetPro: 0.749 ± 0.029	0.813MetGln: 0.813 ± 0.032	0.783MetArg: 0.783 ± 0.03	1.392MetSer: 1.392 ± 0.038	1.066MetThr: 1.066 ± 0.033	1.193MetVal: 1.193 ± 0.035	0.147MetTrp: 0.147 ± 0.012	0.737MetTyr: 0.737 ± 0.029	0.0MetXaa: 0.0 ± 0.0
Asn	3.719AsnAla: 3.719 ± 0.068	0.494AsnCys: 0.494 ± 0.027	3.52AsnAsp: 3.52 ± 0.061	4.094AsnGlu: 4.094 ± 0.08	3.547AsnPhe: 3.547 ± 0.074	4.015AsnGly: 4.015 ± 0.08	1.17AsnHis: 1.17 ± 0.036	5.78AsnIle: 5.78 ± 0.1	6.208AsnLys: 6.208 ± 0.098	5.945AsnLeu: 5.945 ± 0.094	1.253AsnMet: 1.253 ± 0.043	5.042AsnAsn: 5.042 ± 0.099	2.711AsnPro: 2.711 ± 0.064	2.463AsnGln: 2.463 ± 0.078	2.055AsnArg: 2.055 ± 0.055	4.134AsnSer: 4.134 ± 0.08	4.318AsnThr: 4.318 ± 0.082	3.775AsnVal: 3.775 ± 0.084	0.857AsnTrp: 0.857 ± 0.037	3.312AsnTyr: 3.312 ± 0.075	0.0AsnXaa: 0.0 ± 0.0
Pro	1.666ProAla: 1.666 ± 0.047	0.191ProCys: 0.191 ± 0.015	1.533ProAsp: 1.533 ± 0.041	2.219ProGlu: 2.219 ± 0.048	1.748ProPhe: 1.748 ± 0.044	1.492ProGly: 1.492 ± 0.041	0.583ProHis: 0.583 ± 0.026	2.684ProIle: 2.684 ± 0.052	2.846ProLys: 2.846 ± 0.059	2.639ProLeu: 2.639 ± 0.049	0.661ProMet: 0.661 ± 0.027	2.166ProAsn: 2.166 ± 0.049	0.646ProPro: 0.646 ± 0.029	1.003ProGln: 1.003 ± 0.037	0.793ProArg: 0.793 ± 0.031	1.901ProSer: 1.901 ± 0.059	2.051ProThr: 2.051 ± 0.04	2.026ProVal: 2.026 ± 0.051	0.308ProTrp: 0.308 ± 0.021	1.202ProTyr: 1.202 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	1.754GlnAla: 1.754 ± 0.052	0.178GlnCys: 0.178 ± 0.013	1.383GlnAsp: 1.383 ± 0.052	2.339GlnGlu: 2.339 ± 0.051	1.714GlnPhe: 1.714 ± 0.047	1.593GlnGly: 1.593 ± 0.045	0.651GlnHis: 0.651 ± 0.029	2.724GlnIle: 2.724 ± 0.061	3.295GlnLys: 3.295 ± 0.071	3.493GlnLeu: 3.493 ± 0.067	0.752GlnMet: 0.752 ± 0.031	2.219GlnAsn: 2.219 ± 0.057	1.03GlnPro: 1.03 ± 0.04	1.706GlnGln: 1.706 ± 0.051	1.16GlnArg: 1.16 ± 0.037	1.763GlnSer: 1.763 ± 0.043	1.794GlnThr: 1.794 ± 0.041	1.815GlnVal: 1.815 ± 0.046	0.328GlnTrp: 0.328 ± 0.02	1.296GlnTyr: 1.296 ± 0.04	0.0GlnXaa: 0.0 ± 0.0
Arg	1.881ArgAla: 1.881 ± 0.045	0.16ArgCys: 0.16 ± 0.014	1.5ArgAsp: 1.5 ± 0.045	1.89ArgGlu: 1.89 ± 0.049	1.839ArgPhe: 1.839 ± 0.05	1.742ArgGly: 1.742 ± 0.043	0.494ArgHis: 0.494 ± 0.026	2.633ArgIle: 2.633 ± 0.056	3.055ArgLys: 3.055 ± 0.066	2.921ArgLeu: 2.921 ± 0.054	0.763ArgMet: 0.763 ± 0.033	2.014ArgAsn: 2.014 ± 0.047	0.924ArgPro: 0.924 ± 0.034	0.938ArgGln: 0.938 ± 0.037	1.134ArgArg: 1.134 ± 0.043	1.667ArgSer: 1.667 ± 0.05	1.677ArgThr: 1.677 ± 0.039	2.028ArgVal: 2.028 ± 0.045	0.303ArgTrp: 0.303 ± 0.018	1.343ArgTyr: 1.343 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	3.412SerAla: 3.412 ± 0.064	0.578SerCys: 0.578 ± 0.03	3.184SerAsp: 3.184 ± 0.065	3.871SerGlu: 3.871 ± 0.067	4.045SerPhe: 4.045 ± 0.077	4.035SerGly: 4.035 ± 0.085	0.966SerHis: 0.966 ± 0.032	5.302SerIle: 5.302 ± 0.091	5.695SerLys: 5.695 ± 0.08	6.027SerLeu: 6.027 ± 0.108	1.233SerMet: 1.233 ± 0.047	3.932SerAsn: 3.932 ± 0.089	1.736SerPro: 1.736 ± 0.05	1.903SerGln: 1.903 ± 0.051	1.774SerArg: 1.774 ± 0.048	4.06SerSer: 4.06 ± 0.103	3.442SerThr: 3.442 ± 0.074	3.934SerVal: 3.934 ± 0.073	0.709SerTrp: 0.709 ± 0.046	2.72SerTyr: 2.72 ± 0.057	0.0SerXaa: 0.0 ± 0.0
Thr	3.716ThrAla: 3.716 ± 0.086	0.341ThrCys: 0.341 ± 0.022	3.249ThrAsp: 3.249 ± 0.078	3.506ThrGlu: 3.506 ± 0.067	3.048ThrPhe: 3.048 ± 0.066	3.751ThrGly: 3.751 ± 0.076	1.09ThrHis: 1.09 ± 0.035	5.728ThrIle: 5.728 ± 0.083	5.018ThrLys: 5.018 ± 0.087	5.36ThrLeu: 5.36 ± 0.08	0.943ThrMet: 0.943 ± 0.038	3.911ThrAsn: 3.911 ± 0.082	2.325ThrPro: 2.325 ± 0.051	1.925ThrGln: 1.925 ± 0.049	1.552ThrArg: 1.552 ± 0.036	4.079ThrSer: 4.079 ± 0.085	3.874ThrThr: 3.874 ± 0.096	3.9ThrVal: 3.9 ± 0.067	0.498ThrTrp: 0.498 ± 0.028	2.35ThrTyr: 2.35 ± 0.067	0.0ThrXaa: 0.0 ± 0.0
Val	4.185ValAla: 4.185 ± 0.081	0.494ValCys: 0.494 ± 0.028	3.445ValAsp: 3.445 ± 0.059	3.502ValGlu: 3.502 ± 0.067	3.531ValPhe: 3.531 ± 0.067	3.76ValGly: 3.76 ± 0.077	0.925ValHis: 0.925 ± 0.036	4.976ValIle: 4.976 ± 0.083	4.988ValLys: 4.988 ± 0.08	5.965ValLeu: 5.965 ± 0.091	1.225ValMet: 1.225 ± 0.039	4.041ValAsn: 4.041 ± 0.081	1.891ValPro: 1.891 ± 0.046	1.67ValGln: 1.67 ± 0.044	1.846ValArg: 1.846 ± 0.051	4.343ValSer: 4.343 ± 0.096	3.82ValThr: 3.82 ± 0.084	4.195ValVal: 4.195 ± 0.08	0.544ValTrp: 0.544 ± 0.025	2.211ValTyr: 2.211 ± 0.048	0.0ValXaa: 0.0 ± 0.0
Trp	0.562TrpAla: 0.562 ± 0.028	0.084TrpCys: 0.084 ± 0.009	0.525TrpAsp: 0.525 ± 0.042	0.563TrpGlu: 0.563 ± 0.025	0.599TrpPhe: 0.599 ± 0.029	0.553TrpGly: 0.553 ± 0.031	0.188TrpHis: 0.188 ± 0.016	0.72TrpIle: 0.72 ± 0.031	0.837TrpLys: 0.837 ± 0.035	0.934TrpLeu: 0.934 ± 0.034	0.28TrpMet: 0.28 ± 0.018	0.708TrpAsn: 0.708 ± 0.045	0.167TrpPro: 0.167 ± 0.016	0.402TrpGln: 0.402 ± 0.02	0.347TrpArg: 0.347 ± 0.022	0.563TrpSer: 0.563 ± 0.032	0.465TrpThr: 0.465 ± 0.025	0.542TrpVal: 0.542 ± 0.025	0.132TrpTrp: 0.132 ± 0.014	0.388TrpTyr: 0.388 ± 0.023	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.201TyrAla: 2.201 ± 0.053	0.311TyrCys: 0.311 ± 0.021	2.073TyrAsp: 2.073 ± 0.05	2.136TyrGlu: 2.136 ± 0.054	2.398TyrPhe: 2.398 ± 0.052	2.454TyrGly: 2.454 ± 0.055	0.758TyrHis: 0.758 ± 0.029	2.892TyrIle: 2.892 ± 0.059	3.845TyrLys: 3.845 ± 0.065	3.685TyrLeu: 3.685 ± 0.08	0.683TyrMet: 0.683 ± 0.026	2.926TyrAsn: 2.926 ± 0.071	1.321TyrPro: 1.321 ± 0.039	1.534TyrGln: 1.534 ± 0.044	1.367TyrArg: 1.367 ± 0.044	2.481TyrSer: 2.481 ± 0.058	2.474TyrThr: 2.474 ± 0.058	2.076TyrVal: 2.076 ± 0.051	0.428TyrTrp: 0.428 ± 0.026	1.754TyrTyr: 1.754 ± 0.05	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2722 proteins (891548 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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