Amino acid dipepetide frequency for Raccoon polyomavirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.21AlaAla: 5.21 ± 1.439
0.0AlaCys: 0.0 ± 0.0
5.611AlaAsp: 5.611 ± 1.282
2.405AlaGlu: 2.405 ± 1.455
2.806AlaPhe: 2.806 ± 0.641
2.806AlaGly: 2.806 ± 1.346
2.806AlaHis: 2.806 ± 1.027
3.206AlaIle: 3.206 ± 0.892
4.008AlaLys: 4.008 ± 0.369
9.218AlaLeu: 9.218 ± 3.282
0.802AlaMet: 0.802 ± 0.297
1.603AlaAsn: 1.603 ± 0.594
0.401AlaPro: 0.401 ± 0.477
2.405AlaGln: 2.405 ± 0.574
2.004AlaArg: 2.004 ± 0.617
2.004AlaSer: 2.004 ± 0.744
4.008AlaThr: 4.008 ± 0.655
5.21AlaVal: 5.21 ± 1.367
1.603AlaTrp: 1.603 ± 0.606
0.401AlaTyr: 0.401 ± 0.283
0.0AlaXaa: 0.0 ± 0.0
Cys
3.206CysAla: 3.206 ± 0.695
0.0CysCys: 0.0 ± 0.0
0.802CysAsp: 0.802 ± 0.297
0.802CysGlu: 0.802 ± 0.297
2.004CysPhe: 2.004 ± 0.994
2.405CysGly: 2.405 ± 0.67
0.0CysHis: 0.0 ± 0.0
1.202CysIle: 1.202 ± 0.478
4.008CysLys: 4.008 ± 1.43
4.409CysLeu: 4.409 ± 1.609
0.0CysMet: 0.0 ± 0.0
0.802CysAsn: 0.802 ± 0.297
1.603CysPro: 1.603 ± 0.769
0.802CysGln: 0.802 ± 0.297
0.802CysArg: 0.802 ± 0.565
2.004CysSer: 2.004 ± 0.744
2.806CysThr: 2.806 ± 0.641
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
2.004CysTyr: 2.004 ± 0.744
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
1.603AspCys: 1.603 ± 0.594
3.206AspAsp: 3.206 ± 1.189
2.004AspGlu: 2.004 ± 0.617
4.008AspPhe: 4.008 ± 1.486
4.81AspGly: 4.81 ± 0.21
3.206AspHis: 3.206 ± 1.189
1.603AspIle: 1.603 ± 1.909
4.008AspLys: 4.008 ± 0.833
5.611AspLeu: 5.611 ± 1.118
1.202AspMet: 1.202 ± 0.335
5.21AspAsn: 5.21 ± 1.478
8.818AspPro: 8.818 ± 0.244
1.202AspGln: 1.202 ± 0.894
2.004AspArg: 2.004 ± 0.416
4.81AspSer: 4.81 ± 1.039
0.802AspThr: 0.802 ± 0.297
4.409AspVal: 4.409 ± 1.19
2.405AspTrp: 2.405 ± 0.541
0.401AspTyr: 0.401 ± 0.477
0.0AspXaa: 0.0 ± 0.0
Glu
2.806GluAla: 2.806 ± 2.379
0.0GluCys: 0.0 ± 0.0
5.21GluAsp: 5.21 ± 0.689
4.008GluGlu: 4.008 ± 1.234
2.806GluPhe: 2.806 ± 1.027
6.814GluGly: 6.814 ± 1.683
2.004GluHis: 2.004 ± 1.235
0.802GluIle: 0.802 ± 0.659
2.405GluLys: 2.405 ± 0.892
4.81GluLeu: 4.81 ± 0.932
0.802GluMet: 0.802 ± 0.297
3.206GluAsn: 3.206 ± 0.695
1.603GluPro: 1.603 ± 0.769
4.81GluGln: 4.81 ± 1.147
2.405GluArg: 2.405 ± 0.574
2.405GluSer: 2.405 ± 1.867
1.603GluThr: 1.603 ± 0.377
3.607GluVal: 3.607 ± 1.923
0.802GluTrp: 0.802 ± 0.297
0.802GluTyr: 0.802 ± 0.297
0.0GluXaa: 0.0 ± 0.0
Phe
6.814PheAla: 6.814 ± 1.257
3.607PheCys: 3.607 ± 1.434
0.401PheAsp: 0.401 ± 0.283
3.206PheGlu: 3.206 ± 0.684
1.603PhePhe: 1.603 ± 0.807
3.206PheGly: 3.206 ± 1.211
0.0PheHis: 0.0 ± 0.0
2.405PheIle: 2.405 ± 0.892
2.004PheLys: 2.004 ± 0.416
4.409PheLeu: 4.409 ± 1.172
0.802PheMet: 0.802 ± 0.297
0.802PheAsn: 0.802 ± 0.954
2.405PhePro: 2.405 ± 0.956
1.603PheGln: 1.603 ± 0.594
2.004PheArg: 2.004 ± 0.416
7.214PheSer: 7.214 ± 1.563
3.607PheThr: 3.607 ± 0.273
0.401PheVal: 0.401 ± 0.477
0.0PheTrp: 0.0 ± 0.0
0.802PheTyr: 0.802 ± 0.297
0.0PheXaa: 0.0 ± 0.0
Gly
3.206GlyAla: 3.206 ± 0.636
1.603GlyCys: 1.603 ± 0.594
5.21GlyAsp: 5.21 ± 0.689
4.81GlyGlu: 4.81 ± 1.088
4.409GlyPhe: 4.409 ± 0.62
4.81GlyGly: 4.81 ± 0.756
0.0GlyHis: 0.0 ± 0.0
6.814GlyIle: 6.814 ± 2.837
3.607GlyLys: 3.607 ± 0.273
6.012GlyLeu: 6.012 ± 2.817
1.603GlyMet: 1.603 ± 0.769
1.603GlyAsn: 1.603 ± 0.594
4.409GlyPro: 4.409 ± 0.242
2.806GlyGln: 2.806 ± 0.655
2.405GlyArg: 2.405 ± 0.892
4.81GlySer: 4.81 ± 0.577
2.405GlyThr: 2.405 ± 0.67
4.81GlyVal: 4.81 ± 2.668
0.802GlyTrp: 0.802 ± 0.297
1.603GlyTyr: 1.603 ± 1.213
0.0GlyXaa: 0.0 ± 0.0
His
2.405HisAla: 2.405 ± 0.574
0.0HisCys: 0.0 ± 0.0
1.603HisAsp: 1.603 ± 0.594
0.0HisGlu: 0.0 ± 0.0
0.802HisPhe: 0.802 ± 0.762
1.603HisGly: 1.603 ± 0.594
1.202HisHis: 1.202 ± 0.894
0.0HisIle: 0.0 ± 0.0
1.202HisLys: 1.202 ± 0.335
3.607HisLeu: 3.607 ± 0.517
1.202HisMet: 1.202 ± 0.335
0.802HisAsn: 0.802 ± 0.762
3.206HisPro: 3.206 ± 0.684
2.004HisGln: 2.004 ± 0.624
2.405HisArg: 2.405 ± 0.892
1.603HisSer: 1.603 ± 0.606
1.603HisThr: 1.603 ± 0.594
1.603HisVal: 1.603 ± 1.524
0.401HisTrp: 0.401 ± 0.283
1.202HisTyr: 1.202 ± 0.335
0.0HisXaa: 0.0 ± 0.0
Ile
1.202IleAla: 1.202 ± 0.411
1.202IleCys: 1.202 ± 0.335
2.405IleAsp: 2.405 ± 0.67
4.008IleGlu: 4.008 ± 2.347
2.405IlePhe: 2.405 ± 0.892
2.004IleGly: 2.004 ± 0.617
0.802IleHis: 0.802 ± 0.762
0.802IleIle: 0.802 ± 0.297
4.81IleLys: 4.81 ± 0.375
6.413IleLeu: 6.413 ± 1.456
0.0IleMet: 0.0 ± 0.0
2.405IleAsn: 2.405 ± 0.513
2.806IlePro: 2.806 ± 0.641
2.004IleGln: 2.004 ± 0.617
1.202IleArg: 1.202 ± 0.335
2.004IleSer: 2.004 ± 0.617
2.004IleThr: 2.004 ± 1.812
2.806IleVal: 2.806 ± 1.702
0.802IleTrp: 0.802 ± 0.297
1.202IleTyr: 1.202 ± 0.335
0.0IleXaa: 0.0 ± 0.0
Lys
3.607LysAla: 3.607 ± 0.909
2.405LysCys: 2.405 ± 0.892
4.008LysAsp: 4.008 ± 0.833
2.405LysGlu: 2.405 ± 0.892
2.004LysPhe: 2.004 ± 0.576
8.016LysGly: 8.016 ± 1.116
3.206LysHis: 3.206 ± 0.684
0.802LysIle: 0.802 ± 0.954
5.21LysLys: 5.21 ± 1.621
4.409LysLeu: 4.409 ± 0.948
2.004LysMet: 2.004 ± 0.449
4.81LysAsn: 4.81 ± 1.003
3.206LysPro: 3.206 ± 1.024
1.202LysGln: 1.202 ± 0.478
6.413LysArg: 6.413 ± 0.784
6.814LysSer: 6.814 ± 1.781
4.81LysThr: 4.81 ± 1.772
1.603LysVal: 1.603 ± 0.594
0.0LysTrp: 0.0 ± 0.0
3.206LysTyr: 3.206 ± 0.749
0.0LysXaa: 0.0 ± 0.0
Leu
4.409LeuAla: 4.409 ± 0.987
3.607LeuCys: 3.607 ± 0.909
10.822LeuAsp: 10.822 ± 0.672
8.016LeuGlu: 8.016 ± 1.762
6.012LeuPhe: 6.012 ± 0.96
4.008LeuGly: 4.008 ± 1.565
3.607LeuHis: 3.607 ± 0.782
6.413LeuIle: 6.413 ± 0.413
6.413LeuLys: 6.413 ± 1.074
12.425LeuLeu: 12.425 ± 1.57
3.607LeuMet: 3.607 ± 0.608
5.21LeuAsn: 5.21 ± 0.618
4.008LeuPro: 4.008 ± 2.134
4.81LeuGln: 4.81 ± 0.682
2.405LeuArg: 2.405 ± 0.574
6.814LeuSer: 6.814 ± 4.634
5.21LeuThr: 5.21 ± 0.713
3.607LeuVal: 3.607 ± 2.984
1.603LeuTrp: 1.603 ± 0.594
3.206LeuTyr: 3.206 ± 0.334
0.0LeuXaa: 0.0 ± 0.0
Met
2.004MetAla: 2.004 ± 0.715
0.0MetCys: 0.0 ± 0.0
2.405MetAsp: 2.405 ± 0.67
0.401MetGlu: 0.401 ± 0.477
1.202MetPhe: 1.202 ± 0.335
0.802MetGly: 0.802 ± 0.659
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.202MetLys: 1.202 ± 0.478
2.405MetLeu: 2.405 ± 0.892
0.401MetMet: 0.401 ± 0.477
1.202MetAsn: 1.202 ± 0.335
1.202MetPro: 1.202 ± 0.335
0.802MetGln: 0.802 ± 0.297
0.802MetArg: 0.802 ± 0.297
0.0MetSer: 0.0 ± 0.0
2.004MetThr: 2.004 ± 0.814
2.405MetVal: 2.405 ± 0.892
0.401MetTrp: 0.401 ± 0.477
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.607AsnAla: 3.607 ± 1.317
2.405AsnCys: 2.405 ± 0.892
0.0AsnAsp: 0.0 ± 0.0
4.008AsnGlu: 4.008 ± 0.833
3.607AsnPhe: 3.607 ± 0.782
3.607AsnGly: 3.607 ± 1.126
1.603AsnHis: 1.603 ± 1.524
3.607AsnIle: 3.607 ± 1.317
3.607AsnLys: 3.607 ± 0.909
6.814AsnLeu: 6.814 ± 0.962
0.401AsnMet: 0.401 ± 0.283
2.004AsnAsn: 2.004 ± 0.617
0.802AsnPro: 0.802 ± 0.954
2.405AsnGln: 2.405 ± 0.922
0.0AsnArg: 0.0 ± 0.0
3.607AsnSer: 3.607 ± 1.005
2.004AsnThr: 2.004 ± 0.715
0.802AsnVal: 0.802 ± 0.297
0.802AsnTrp: 0.802 ± 0.762
0.401AsnTyr: 0.401 ± 0.477
0.0AsnXaa: 0.0 ± 0.0
Pro
4.81ProAla: 4.81 ± 0.682
0.802ProCys: 0.802 ± 0.297
3.206ProAsp: 3.206 ± 1.776
0.802ProGlu: 0.802 ± 0.954
0.0ProPhe: 0.0 ± 0.0
2.405ProGly: 2.405 ± 0.574
3.206ProHis: 3.206 ± 0.684
3.206ProIle: 3.206 ± 1.538
4.008ProLys: 4.008 ± 1.912
6.413ProLeu: 6.413 ± 0.784
2.405ProMet: 2.405 ± 0.868
1.202ProAsn: 1.202 ± 0.478
5.21ProPro: 5.21 ± 1.478
0.802ProGln: 0.802 ± 0.297
2.405ProArg: 2.405 ± 0.67
7.615ProSer: 7.615 ± 1.676
3.206ProThr: 3.206 ± 0.334
3.607ProVal: 3.607 ± 1.005
0.0ProTrp: 0.0 ± 0.0
2.405ProTyr: 2.405 ± 0.513
0.0ProXaa: 0.0 ± 0.0
Gln
2.806GlnAla: 2.806 ± 1.308
1.603GlnCys: 1.603 ± 0.377
2.405GlnAsp: 2.405 ± 0.892
0.0GlnGlu: 0.0 ± 0.0
2.004GlnPhe: 2.004 ± 0.617
2.405GlnGly: 2.405 ± 0.67
0.401GlnHis: 0.401 ± 0.283
2.806GlnIle: 2.806 ± 0.373
5.611GlnLys: 5.611 ± 1.227
4.81GlnLeu: 4.81 ± 0.21
0.401GlnMet: 0.401 ± 0.282
3.607GlnAsn: 3.607 ± 1.317
1.603GlnPro: 1.603 ± 0.769
2.405GlnGln: 2.405 ± 0.892
1.202GlnArg: 1.202 ± 0.335
3.206GlnSer: 3.206 ± 1.211
4.008GlnThr: 4.008 ± 0.369
0.401GlnVal: 0.401 ± 0.283
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
1.603ArgAla: 1.603 ± 0.594
0.401ArgCys: 0.401 ± 0.283
4.008ArgAsp: 4.008 ± 0.833
4.81ArgGlu: 4.81 ± 1.147
1.603ArgPhe: 1.603 ± 0.594
1.202ArgGly: 1.202 ± 0.335
0.0ArgHis: 0.0 ± 0.0
1.202ArgIle: 1.202 ± 0.878
3.206ArgLys: 3.206 ± 0.695
4.409ArgLeu: 4.409 ± 0.993
0.401ArgMet: 0.401 ± 0.477
1.603ArgAsn: 1.603 ± 0.594
0.802ArgPro: 0.802 ± 0.297
1.202ArgGln: 1.202 ± 0.894
3.607ArgArg: 3.607 ± 1.317
2.405ArgSer: 2.405 ± 0.892
1.603ArgThr: 1.603 ± 0.594
2.806ArgVal: 2.806 ± 0.641
2.004ArgTrp: 2.004 ± 0.617
1.202ArgTyr: 1.202 ± 1.432
0.0ArgXaa: 0.0 ± 0.0
Ser
4.409SerAla: 4.409 ± 2.321
2.405SerCys: 2.405 ± 0.769
3.206SerAsp: 3.206 ± 0.749
2.004SerGlu: 2.004 ± 0.416
4.008SerPhe: 4.008 ± 0.885
7.214SerGly: 7.214 ± 1.554
2.405SerHis: 2.405 ± 0.574
2.405SerIle: 2.405 ± 0.28
4.409SerLys: 4.409 ± 1.609
8.016SerLeu: 8.016 ± 3.79
0.802SerMet: 0.802 ± 0.297
4.81SerAsn: 4.81 ± 1.817
6.012SerPro: 6.012 ± 1.366
5.611SerGln: 5.611 ± 0.359
3.607SerArg: 3.607 ± 0.909
12.826SerSer: 12.826 ± 3.422
7.214SerThr: 7.214 ± 0.976
2.004SerVal: 2.004 ± 0.617
0.802SerTrp: 0.802 ± 0.762
1.202SerTyr: 1.202 ± 1.432
0.0SerXaa: 0.0 ± 0.0
Thr
2.004ThrAla: 2.004 ± 0.617
3.607ThrCys: 3.607 ± 1.039
2.405ThrAsp: 2.405 ± 0.513
3.206ThrGlu: 3.206 ± 1.538
2.806ThrPhe: 2.806 ± 1.027
3.206ThrGly: 3.206 ± 0.82
0.0ThrHis: 0.0 ± 0.0
2.004ThrIle: 2.004 ± 1.235
3.206ThrLys: 3.206 ± 0.695
5.611ThrLeu: 5.611 ± 0.411
0.0ThrMet: 0.0 ± 0.0
0.802ThrAsn: 0.802 ± 0.954
5.611ThrPro: 5.611 ± 0.359
1.603ThrGln: 1.603 ± 0.594
2.405ThrArg: 2.405 ± 0.892
8.016ThrSer: 8.016 ± 1.201
2.004ThrThr: 2.004 ± 0.789
4.409ThrVal: 4.409 ± 1.495
1.603ThrTrp: 1.603 ± 0.727
0.802ThrTyr: 0.802 ± 0.297
0.0ThrXaa: 0.0 ± 0.0
Val
2.004ValAla: 2.004 ± 0.532
3.206ValCys: 3.206 ± 0.695
0.802ValAsp: 0.802 ± 0.297
4.81ValGlu: 4.81 ± 0.594
0.802ValPhe: 0.802 ± 0.762
3.607ValGly: 3.607 ± 1.851
2.004ValHis: 2.004 ± 0.617
2.806ValIle: 2.806 ± 0.373
3.607ValLys: 3.607 ± 1.061
3.206ValLeu: 3.206 ± 1.538
2.004ValMet: 2.004 ± 0.416
3.607ValAsn: 3.607 ± 3.08
2.806ValPro: 2.806 ± 1.332
1.603ValGln: 1.603 ± 0.594
2.004ValArg: 2.004 ± 1.235
2.004ValSer: 2.004 ± 1.102
2.405ValThr: 2.405 ± 0.67
1.603ValVal: 1.603 ± 0.606
1.603ValTrp: 1.603 ± 0.807
0.802ValTyr: 0.802 ± 0.762
0.0ValXaa: 0.0 ± 0.0
Trp
1.603TrpAla: 1.603 ± 0.594
0.802TrpCys: 0.802 ± 0.444
1.603TrpAsp: 1.603 ± 0.606
1.202TrpGlu: 1.202 ± 0.894
1.603TrpPhe: 1.603 ± 0.377
1.202TrpGly: 1.202 ± 0.478
0.802TrpHis: 0.802 ± 0.762
0.0TrpIle: 0.0 ± 0.0
0.401TrpLys: 0.401 ± 0.283
1.603TrpLeu: 1.603 ± 0.606
0.401TrpMet: 0.401 ± 0.283
0.802TrpAsn: 0.802 ± 0.297
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
1.603TrpSer: 1.603 ± 0.606
0.0TrpThr: 0.0 ± 0.0
1.202TrpVal: 1.202 ± 0.894
1.202TrpTrp: 1.202 ± 0.478
0.802TrpTyr: 0.802 ± 0.297
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.802TyrAla: 0.802 ± 0.297
0.401TyrCys: 0.401 ± 0.283
2.004TyrAsp: 2.004 ± 0.416
0.802TyrGlu: 0.802 ± 0.444
0.802TyrPhe: 0.802 ± 0.954
1.603TyrGly: 1.603 ± 0.606
1.202TyrHis: 1.202 ± 0.335
1.202TyrIle: 1.202 ± 0.335
3.206TyrLys: 3.206 ± 0.749
1.603TyrLeu: 1.603 ± 0.377
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
1.202TyrPro: 1.202 ± 1.432
2.004TyrGln: 2.004 ± 0.744
0.0TyrArg: 0.0 ± 0.0
3.607TyrSer: 3.607 ± 1.785
2.004TyrThr: 2.004 ± 0.416
0.0TyrVal: 0.0 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
1.202TyrTyr: 1.202 ± 0.335
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2496 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski