Amino acid dipepetide frequency for Microbacterium ginsengiterrae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	20.589AlaAla: 20.589 ± 0.219	0.61AlaCys: 0.61 ± 0.028	8.907AlaAsp: 8.907 ± 0.114	8.918AlaGlu: 8.918 ± 0.096	4.184AlaPhe: 4.184 ± 0.064	12.479AlaGly: 12.479 ± 0.118	2.46AlaHis: 2.46 ± 0.041	6.138AlaIle: 6.138 ± 0.07	2.392AlaLys: 2.392 ± 0.056	14.408AlaLeu: 14.408 ± 0.146	2.682AlaMet: 2.682 ± 0.044	2.273AlaAsn: 2.273 ± 0.044	6.56AlaPro: 6.56 ± 0.108	3.983AlaGln: 3.983 ± 0.057	8.862AlaArg: 8.862 ± 0.119	7.66AlaSer: 7.66 ± 0.08	7.226AlaThr: 7.226 ± 0.169	11.681AlaVal: 11.681 ± 0.116	2.017AlaTrp: 2.017 ± 0.04	2.461AlaTyr: 2.461 ± 0.044	0.0AlaXaa: 0.0 ± 0.0
Cys	0.662CysAla: 0.662 ± 0.027	0.044CysCys: 0.044 ± 0.007	0.299CysAsp: 0.299 ± 0.017	0.243CysGlu: 0.243 ± 0.015	0.163CysPhe: 0.163 ± 0.011	0.486CysGly: 0.486 ± 0.021	0.11CysHis: 0.11 ± 0.011	0.22CysIle: 0.22 ± 0.012	0.05CysLys: 0.05 ± 0.007	0.398CysLeu: 0.398 ± 0.019	0.073CysMet: 0.073 ± 0.008	0.09CysAsn: 0.09 ± 0.009	0.259CysPro: 0.259 ± 0.016	0.098CysGln: 0.098 ± 0.009	0.289CysArg: 0.289 ± 0.015	0.326CysSer: 0.326 ± 0.018	0.296CysThr: 0.296 ± 0.018	0.392CysVal: 0.392 ± 0.017	0.067CysTrp: 0.067 ± 0.006	0.107CysTyr: 0.107 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	10.573AspAla: 10.573 ± 0.201	0.208AspCys: 0.208 ± 0.014	4.434AspAsp: 4.434 ± 0.071	4.603AspGlu: 4.603 ± 0.07	1.808AspPhe: 1.808 ± 0.04	6.614AspGly: 6.614 ± 0.102	1.112AspHis: 1.112 ± 0.029	2.566AspIle: 2.566 ± 0.045	0.893AspLys: 0.893 ± 0.034	6.2AspLeu: 6.2 ± 0.074	0.805AspMet: 0.805 ± 0.026	0.973AspAsn: 0.973 ± 0.029	4.156AspPro: 4.156 ± 0.066	1.576AspGln: 1.576 ± 0.038	4.475AspArg: 4.475 ± 0.072	2.686AspSer: 2.686 ± 0.047	2.827AspThr: 2.827 ± 0.058	5.499AspVal: 5.499 ± 0.076	1.027AspTrp: 1.027 ± 0.032	1.318AspTyr: 1.318 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	7.112GluAla: 7.112 ± 0.094	0.239GluCys: 0.239 ± 0.015	3.112GluAsp: 3.112 ± 0.061	2.953GluGlu: 2.953 ± 0.056	1.831GluPhe: 1.831 ± 0.042	4.0GluGly: 4.0 ± 0.07	1.515GluHis: 1.515 ± 0.036	3.061GluIle: 3.061 ± 0.051	1.286GluLys: 1.286 ± 0.043	6.574GluLeu: 6.574 ± 0.085	0.938GluMet: 0.938 ± 0.029	1.346GluAsn: 1.346 ± 0.033	3.114GluPro: 3.114 ± 0.058	2.37GluGln: 2.37 ± 0.048	5.251GluArg: 5.251 ± 0.083	3.086GluSer: 3.086 ± 0.058	3.092GluThr: 3.092 ± 0.058	4.483GluVal: 4.483 ± 0.068	0.93GluTrp: 0.93 ± 0.025	1.254GluTyr: 1.254 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	4.575PheAla: 4.575 ± 0.056	0.152PheCys: 0.152 ± 0.011	2.513PheAsp: 2.513 ± 0.055	1.852PheGlu: 1.852 ± 0.043	1.103PhePhe: 1.103 ± 0.039	3.4PheGly: 3.4 ± 0.055	0.58PheHis: 0.58 ± 0.022	1.289PheIle: 1.289 ± 0.037	0.425PheLys: 0.425 ± 0.02	2.946PheLeu: 2.946 ± 0.06	0.449PheMet: 0.449 ± 0.02	0.687PheAsn: 0.687 ± 0.025	1.416PhePro: 1.416 ± 0.033	0.834PheGln: 0.834 ± 0.029	1.822PheArg: 1.822 ± 0.042	1.785PheSer: 1.785 ± 0.046	2.129PheThr: 2.129 ± 0.043	2.867PheVal: 2.867 ± 0.05	0.565PheTrp: 0.565 ± 0.022	0.684PheTyr: 0.684 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	10.921GlyAla: 10.921 ± 0.111	0.581GlyCys: 0.581 ± 0.022	5.17GlyAsp: 5.17 ± 0.087	5.078GlyGlu: 5.078 ± 0.064	3.345GlyPhe: 3.345 ± 0.052	7.238GlyGly: 7.238 ± 0.091	1.705GlyHis: 1.705 ± 0.042	5.472GlyIle: 5.472 ± 0.07	1.808GlyLys: 1.808 ± 0.058	8.48GlyLeu: 8.48 ± 0.091	1.956GlyMet: 1.956 ± 0.041	1.671GlyAsn: 1.671 ± 0.047	3.604GlyPro: 3.604 ± 0.05	2.337GlyGln: 2.337 ± 0.043	6.143GlyArg: 6.143 ± 0.085	5.447GlySer: 5.447 ± 0.076	5.654GlyThr: 5.654 ± 0.089	7.676GlyVal: 7.676 ± 0.08	1.734GlyTrp: 1.734 ± 0.048	2.323GlyTyr: 2.323 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	2.319HisAla: 2.319 ± 0.047	0.088HisCys: 0.088 ± 0.008	1.3HisAsp: 1.3 ± 0.038	1.173HisGlu: 1.173 ± 0.03	0.551HisPhe: 0.551 ± 0.022	1.958HisGly: 1.958 ± 0.047	0.545HisHis: 0.545 ± 0.023	0.751HisIle: 0.751 ± 0.028	0.229HisLys: 0.229 ± 0.015	1.984HisLeu: 1.984 ± 0.045	0.293HisMet: 0.293 ± 0.016	0.353HisAsn: 0.353 ± 0.017	1.524HisPro: 1.524 ± 0.032	0.491HisGln: 0.491 ± 0.025	1.609HisArg: 1.609 ± 0.036	0.882HisSer: 0.882 ± 0.026	0.91HisThr: 0.91 ± 0.028	1.625HisVal: 1.625 ± 0.036	0.302HisTrp: 0.302 ± 0.015	0.404HisTyr: 0.404 ± 0.016	0.0HisXaa: 0.0 ± 0.0
Ile	7.899IleAla: 7.899 ± 0.096	0.255IleCys: 0.255 ± 0.016	3.717IleAsp: 3.717 ± 0.054	3.103IleGlu: 3.103 ± 0.06	1.217IlePhe: 1.217 ± 0.033	5.072IleGly: 5.072 ± 0.068	0.737IleHis: 0.737 ± 0.024	2.031IleIle: 2.031 ± 0.043	0.695IleLys: 0.695 ± 0.028	4.202IleLeu: 4.202 ± 0.065	0.659IleMet: 0.659 ± 0.027	0.917IleAsn: 0.917 ± 0.028	2.682IlePro: 2.682 ± 0.047	1.064IleGln: 1.064 ± 0.03	3.177IleArg: 3.177 ± 0.051	2.472IleSer: 2.472 ± 0.045	3.024IleThr: 3.024 ± 0.052	4.963IleVal: 4.963 ± 0.075	0.635IleTrp: 0.635 ± 0.023	0.805IleTyr: 0.805 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	2.202LysAla: 2.202 ± 0.05	0.053LysCys: 0.053 ± 0.007	1.092LysAsp: 1.092 ± 0.034	0.804LysGlu: 0.804 ± 0.03	0.415LysPhe: 0.415 ± 0.019	1.359LysGly: 1.359 ± 0.043	0.452LysHis: 0.452 ± 0.019	0.824LysIle: 0.824 ± 0.034	0.683LysLys: 0.683 ± 0.031	1.661LysLeu: 1.661 ± 0.048	0.34LysMet: 0.34 ± 0.015	0.442LysAsn: 0.442 ± 0.024	1.077LysPro: 1.077 ± 0.037	0.629LysGln: 0.629 ± 0.024	1.333LysArg: 1.333 ± 0.037	1.037LysSer: 1.037 ± 0.035	1.176LysThr: 1.176 ± 0.04	1.415LysVal: 1.415 ± 0.044	0.236LysTrp: 0.236 ± 0.015	0.413LysTyr: 0.413 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	14.38LeuAla: 14.38 ± 0.139	0.506LeuCys: 0.506 ± 0.021	6.635LeuAsp: 6.635 ± 0.08	5.156LeuGlu: 5.156 ± 0.077	3.07LeuPhe: 3.07 ± 0.054	8.904LeuGly: 8.904 ± 0.109	1.859LeuHis: 1.859 ± 0.042	5.093LeuIle: 5.093 ± 0.082	1.569LeuLys: 1.569 ± 0.041	10.232LeuLeu: 10.232 ± 0.137	1.613LeuMet: 1.613 ± 0.037	1.875LeuAsn: 1.875 ± 0.04	5.386LeuPro: 5.386 ± 0.076	2.532LeuGln: 2.532 ± 0.046	7.473LeuArg: 7.473 ± 0.089	5.987LeuSer: 5.987 ± 0.083	6.305LeuThr: 6.305 ± 0.075	9.024LeuVal: 9.024 ± 0.099	1.406LeuTrp: 1.406 ± 0.039	1.736LeuTyr: 1.736 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	1.999MetAla: 1.999 ± 0.044	0.09MetCys: 0.09 ± 0.008	0.782MetAsp: 0.782 ± 0.025	0.57MetGlu: 0.57 ± 0.022	0.561MetPhe: 0.561 ± 0.022	1.18MetGly: 1.18 ± 0.031	0.35MetHis: 0.35 ± 0.018	0.947MetIle: 0.947 ± 0.03	0.415MetLys: 0.415 ± 0.019	2.108MetLeu: 2.108 ± 0.043	0.323MetMet: 0.323 ± 0.021	0.508MetAsn: 0.508 ± 0.019	1.169MetPro: 1.169 ± 0.029	0.543MetGln: 0.543 ± 0.019	1.375MetArg: 1.375 ± 0.039	1.537MetSer: 1.537 ± 0.037	1.76MetThr: 1.76 ± 0.039	1.251MetVal: 1.251 ± 0.033	0.206MetTrp: 0.206 ± 0.012	0.273MetTyr: 0.273 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	2.577AsnAla: 2.577 ± 0.054	0.085AsnCys: 0.085 ± 0.009	1.235AsnAsp: 1.235 ± 0.033	1.015AsnGlu: 1.015 ± 0.032	0.621AsnPhe: 0.621 ± 0.025	1.929AsnGly: 1.929 ± 0.046	0.36AsnHis: 0.36 ± 0.02	0.88AsnIle: 0.88 ± 0.028	0.358AsnLys: 0.358 ± 0.019	1.831AsnLeu: 1.831 ± 0.043	0.318AsnMet: 0.318 ± 0.016	0.446AsnAsn: 0.446 ± 0.022	1.555AsnPro: 1.555 ± 0.034	0.531AsnGln: 0.531 ± 0.022	1.239AsnArg: 1.239 ± 0.036	1.002AsnSer: 1.002 ± 0.032	1.174AsnThr: 1.174 ± 0.037	1.604AsnVal: 1.604 ± 0.038	0.336AsnTrp: 0.336 ± 0.018	0.486AsnTyr: 0.486 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	7.214ProAla: 7.214 ± 0.108	0.174ProCys: 0.174 ± 0.015	3.907ProAsp: 3.907 ± 0.053	3.828ProGlu: 3.828 ± 0.061	1.762ProPhe: 1.762 ± 0.033	4.78ProGly: 4.78 ± 0.062	1.076ProHis: 1.076 ± 0.031	2.292ProIle: 2.292 ± 0.041	0.951ProLys: 0.951 ± 0.03	4.867ProLeu: 4.867 ± 0.069	0.812ProMet: 0.812 ± 0.025	1.017ProAsn: 1.017 ± 0.028	2.028ProPro: 2.028 ± 0.055	1.544ProGln: 1.544 ± 0.033	3.222ProArg: 3.222 ± 0.057	2.949ProSer: 2.949 ± 0.045	3.336ProThr: 3.336 ± 0.052	4.893ProVal: 4.893 ± 0.07	0.907ProTrp: 0.907 ± 0.027	1.064ProTyr: 1.064 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	3.502GlnAla: 3.502 ± 0.057	0.103GlnCys: 0.103 ± 0.009	1.543GlnAsp: 1.543 ± 0.032	1.313GlnGlu: 1.313 ± 0.039	0.883GlnPhe: 0.883 ± 0.029	2.147GlnGly: 2.147 ± 0.045	0.612GlnHis: 0.612 ± 0.022	1.437GlnIle: 1.437 ± 0.034	0.633GlnLys: 0.633 ± 0.025	3.003GlnLeu: 3.003 ± 0.055	0.544GlnMet: 0.544 ± 0.021	0.74GlnAsn: 0.74 ± 0.028	1.446GlnPro: 1.446 ± 0.033	1.157GlnGln: 1.157 ± 0.035	2.421GlnArg: 2.421 ± 0.049	1.511GlnSer: 1.511 ± 0.04	1.584GlnThr: 1.584 ± 0.036	2.352GlnVal: 2.352 ± 0.047	0.47GlnTrp: 0.47 ± 0.021	0.634GlnTyr: 0.634 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	8.783ArgAla: 8.783 ± 0.125	0.269ArgCys: 0.269 ± 0.013	4.26ArgAsp: 4.26 ± 0.071	4.157ArgGlu: 4.157 ± 0.067	2.418ArgPhe: 2.418 ± 0.045	5.328ArgGly: 5.328 ± 0.068	1.465ArgHis: 1.465 ± 0.038	3.97ArgIle: 3.97 ± 0.058	1.268ArgLys: 1.268 ± 0.035	7.194ArgLeu: 7.194 ± 0.097	1.824ArgMet: 1.824 ± 0.038	1.304ArgAsn: 1.304 ± 0.029	3.534ArgPro: 3.534 ± 0.065	1.991ArgGln: 1.991 ± 0.041	6.539ArgArg: 6.539 ± 0.104	4.089ArgSer: 4.089 ± 0.066	4.491ArgThr: 4.491 ± 0.067	5.922ArgVal: 5.922 ± 0.071	1.207ArgTrp: 1.207 ± 0.035	1.513ArgTyr: 1.513 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	7.473SerAla: 7.473 ± 0.086	0.279SerCys: 0.279 ± 0.016	3.603SerAsp: 3.603 ± 0.055	2.953SerGlu: 2.953 ± 0.052	1.999SerPhe: 1.999 ± 0.038	5.699SerGly: 5.699 ± 0.078	0.897SerHis: 0.897 ± 0.028	2.884SerIle: 2.884 ± 0.05	0.971SerLys: 0.971 ± 0.031	5.2SerLeu: 5.2 ± 0.07	1.201SerMet: 1.201 ± 0.027	1.064SerAsn: 1.064 ± 0.031	2.918SerPro: 2.918 ± 0.047	1.343SerGln: 1.343 ± 0.033	3.639SerArg: 3.639 ± 0.055	3.385SerSer: 3.385 ± 0.058	3.743SerThr: 3.743 ± 0.057	4.69SerVal: 4.69 ± 0.063	1.035SerTrp: 1.035 ± 0.033	1.147SerTyr: 1.147 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	8.138ThrAla: 8.138 ± 0.102	0.267ThrCys: 0.267 ± 0.013	3.967ThrAsp: 3.967 ± 0.145	3.097ThrGlu: 3.097 ± 0.043	1.844ThrPhe: 1.844 ± 0.046	5.936ThrGly: 5.936 ± 0.084	1.087ThrHis: 1.087 ± 0.029	3.14ThrIle: 3.14 ± 0.058	1.048ThrLys: 1.048 ± 0.031	5.884ThrLeu: 5.884 ± 0.071	0.977ThrMet: 0.977 ± 0.03	1.168ThrAsn: 1.168 ± 0.04	3.699ThrPro: 3.699 ± 0.061	1.49ThrGln: 1.49 ± 0.041	3.682ThrArg: 3.682 ± 0.062	3.203ThrSer: 3.203 ± 0.052	3.927ThrThr: 3.927 ± 0.076	5.68ThrVal: 5.68 ± 0.094	0.951ThrTrp: 0.951 ± 0.036	1.198ThrTyr: 1.198 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	11.317ValAla: 11.317 ± 0.115	0.473ValCys: 0.473 ± 0.017	5.636ValAsp: 5.636 ± 0.074	4.808ValGlu: 4.808 ± 0.07	2.934ValPhe: 2.934 ± 0.052	6.806ValGly: 6.806 ± 0.078	1.727ValHis: 1.727 ± 0.043	4.725ValIle: 4.725 ± 0.068	1.376ValLys: 1.376 ± 0.042	9.615ValLeu: 9.615 ± 0.126	1.504ValMet: 1.504 ± 0.035	1.697ValAsn: 1.697 ± 0.037	4.659ValPro: 4.659 ± 0.057	2.355ValGln: 2.355 ± 0.043	6.062ValArg: 6.062 ± 0.08	4.963ValSer: 4.963 ± 0.07	5.497ValThr: 5.497 ± 0.076	8.459ValVal: 8.459 ± 0.102	1.136ValTrp: 1.136 ± 0.029	1.503ValTyr: 1.503 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.714TrpAla: 1.714 ± 0.039	0.101TrpCys: 0.101 ± 0.009	0.899TrpAsp: 0.899 ± 0.029	0.743TrpGlu: 0.743 ± 0.027	0.612TrpPhe: 0.612 ± 0.024	1.14TrpGly: 1.14 ± 0.031	0.359TrpHis: 0.359 ± 0.019	0.831TrpIle: 0.831 ± 0.028	0.293TrpLys: 0.293 ± 0.014	1.761TrpLeu: 1.761 ± 0.047	0.369TrpMet: 0.369 ± 0.017	0.514TrpAsn: 0.514 ± 0.023	0.751TrpPro: 0.751 ± 0.022	0.612TrpGln: 0.612 ± 0.023	1.268TrpArg: 1.268 ± 0.035	1.024TrpSer: 1.024 ± 0.031	1.014TrpThr: 1.014 ± 0.031	1.173TrpVal: 1.173 ± 0.033	0.406TrpTrp: 0.406 ± 0.02	0.332TrpTyr: 0.332 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.54TyrAla: 2.54 ± 0.046	0.096TyrCys: 0.096 ± 0.008	1.34TyrAsp: 1.34 ± 0.037	1.18TyrGlu: 1.18 ± 0.035	0.75TyrPhe: 0.75 ± 0.024	1.89TyrGly: 1.89 ± 0.042	0.282TyrHis: 0.282 ± 0.017	0.774TyrIle: 0.774 ± 0.027	0.303TyrLys: 0.303 ± 0.017	2.192TyrLeu: 2.192 ± 0.044	0.268TyrMet: 0.268 ± 0.015	0.497TyrAsn: 0.497 ± 0.024	1.086TyrPro: 1.086 ± 0.031	0.555TyrGln: 0.555 ± 0.028	1.648TyrArg: 1.648 ± 0.038	1.093TyrSer: 1.093 ± 0.033	1.22TyrThr: 1.22 ± 0.039	1.599TyrVal: 1.599 ± 0.034	0.341TyrTrp: 0.341 ± 0.017	0.485TyrTyr: 0.485 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3754 proteins (1274925 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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