Amino acid dipepetide frequency for Thanatephorus cucumeris (strain AG1-IB / isolate 7/3/14) (Lettuce bottom rot fungus) (Rhizoctonia solani)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.207AlaAla: 8.207 ± 0.067	1.048AlaCys: 1.048 ± 0.016	3.815AlaAsp: 3.815 ± 0.029	4.732AlaGlu: 4.732 ± 0.038	3.049AlaPhe: 3.049 ± 0.027	5.697AlaGly: 5.697 ± 0.037	2.023AlaHis: 2.023 ± 0.019	4.229AlaIle: 4.229 ± 0.03	3.931AlaLys: 3.931 ± 0.029	8.266AlaLeu: 8.266 ± 0.054	1.77AlaMet: 1.77 ± 0.016	3.054AlaAsn: 3.054 ± 0.022	5.703AlaPro: 5.703 ± 0.049	3.516AlaGln: 3.516 ± 0.029	5.247AlaArg: 5.247 ± 0.031	7.444AlaSer: 7.444 ± 0.047	5.432AlaThr: 5.432 ± 0.038	4.903AlaVal: 4.903 ± 0.032	1.151AlaTrp: 1.151 ± 0.015	2.316AlaTyr: 2.316 ± 0.023	0.003AlaXaa: 0.003 ± 0.001
Cys	0.926CysAla: 0.926 ± 0.014	0.203CysCys: 0.203 ± 0.006	0.621CysAsp: 0.621 ± 0.013	0.592CysGlu: 0.592 ± 0.011	0.436CysPhe: 0.436 ± 0.01	0.888CysGly: 0.888 ± 0.013	0.307CysHis: 0.307 ± 0.008	0.682CysIle: 0.682 ± 0.012	0.521CysLys: 0.521 ± 0.01	1.114CysLeu: 1.114 ± 0.015	0.243CysMet: 0.243 ± 0.007	0.41CysAsn: 0.41 ± 0.009	0.691CysPro: 0.691 ± 0.012	0.421CysGln: 0.421 ± 0.009	0.72CysArg: 0.72 ± 0.013	0.924CysSer: 0.924 ± 0.014	0.749CysThr: 0.749 ± 0.013	0.815CysVal: 0.815 ± 0.014	0.206CysTrp: 0.206 ± 0.006	0.348CysTyr: 0.348 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.543AspAla: 4.543 ± 0.031	0.56AspCys: 0.56 ± 0.012	3.694AspAsp: 3.694 ± 0.035	4.141AspGlu: 4.141 ± 0.034	1.857AspPhe: 1.857 ± 0.02	3.958AspGly: 3.958 ± 0.032	1.206AspHis: 1.206 ± 0.015	2.956AspIle: 2.956 ± 0.024	2.32AspLys: 2.32 ± 0.023	4.782AspLeu: 4.782 ± 0.031	1.157AspMet: 1.157 ± 0.015	1.808AspAsn: 1.808 ± 0.017	3.437AspPro: 3.437 ± 0.023	1.805AspGln: 1.805 ± 0.017	2.887AspArg: 2.887 ± 0.025	4.21AspSer: 4.21 ± 0.03	2.91AspThr: 2.91 ± 0.021	3.536AspVal: 3.536 ± 0.024	0.859AspTrp: 0.859 ± 0.014	1.524AspTyr: 1.524 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	4.878GluAla: 4.878 ± 0.037	0.65GluCys: 0.65 ± 0.012	3.777GluAsp: 3.777 ± 0.034	4.815GluGlu: 4.815 ± 0.047	1.927GluPhe: 1.927 ± 0.018	3.593GluGly: 3.593 ± 0.029	1.458GluHis: 1.458 ± 0.017	2.926GluIle: 2.926 ± 0.027	3.01GluLys: 3.01 ± 0.028	5.464GluLeu: 5.464 ± 0.045	1.235GluMet: 1.235 ± 0.018	1.936GluAsn: 1.936 ± 0.02	3.046GluPro: 3.046 ± 0.031	2.313GluGln: 2.313 ± 0.024	3.901GluArg: 3.901 ± 0.035	4.357GluSer: 4.357 ± 0.031	3.197GluThr: 3.197 ± 0.031	3.44GluVal: 3.44 ± 0.024	0.977GluTrp: 0.977 ± 0.014	1.619GluTyr: 1.619 ± 0.017	0.001GluXaa: 0.001 ± 0.001
Phe	2.926PheAla: 2.926 ± 0.026	0.488PheCys: 0.488 ± 0.01	2.088PheAsp: 2.088 ± 0.019	1.99PheGlu: 1.99 ± 0.019	1.323PhePhe: 1.323 ± 0.019	2.798PheGly: 2.798 ± 0.031	0.833PheHis: 0.833 ± 0.012	1.703PheIle: 1.703 ± 0.021	1.491PheLys: 1.491 ± 0.017	3.07PheLeu: 3.07 ± 0.027	0.717PheMet: 0.717 ± 0.011	1.387PheAsn: 1.387 ± 0.017	1.825PhePro: 1.825 ± 0.019	1.244PheGln: 1.244 ± 0.017	1.818PheArg: 1.818 ± 0.022	3.054PheSer: 3.054 ± 0.027	2.089PheThr: 2.089 ± 0.02	2.419PheVal: 2.419 ± 0.022	0.55PheTrp: 0.55 ± 0.01	0.97PheTyr: 0.97 ± 0.012	0.001PheXaa: 0.001 ± 0.0
Gly	5.567GlyAla: 5.567 ± 0.034	0.808GlyCys: 0.808 ± 0.014	3.356GlyAsp: 3.356 ± 0.027	3.407GlyGlu: 3.407 ± 0.025	2.474GlyPhe: 2.474 ± 0.025	5.514GlyGly: 5.514 ± 0.057	1.811GlyHis: 1.811 ± 0.022	3.433GlyIle: 3.433 ± 0.03	3.37GlyLys: 3.37 ± 0.028	5.94GlyLeu: 5.94 ± 0.036	1.503GlyMet: 1.503 ± 0.021	2.389GlyAsn: 2.389 ± 0.023	3.634GlyPro: 3.634 ± 0.031	2.436GlyGln: 2.436 ± 0.022	4.028GlyArg: 4.028 ± 0.037	6.232GlySer: 6.232 ± 0.043	4.469GlyThr: 4.469 ± 0.033	4.325GlyVal: 4.325 ± 0.03	1.168GlyTrp: 1.168 ± 0.015	2.025GlyTyr: 2.025 ± 0.021	0.003GlyXaa: 0.003 ± 0.001
His	2.017HisAla: 2.017 ± 0.022	0.306HisCys: 0.306 ± 0.007	1.26HisAsp: 1.26 ± 0.016	1.327HisGlu: 1.327 ± 0.019	0.907HisPhe: 0.907 ± 0.013	1.571HisGly: 1.571 ± 0.019	0.767HisHis: 0.767 ± 0.017	1.384HisIle: 1.384 ± 0.017	0.917HisLys: 0.917 ± 0.013	2.293HisLeu: 2.293 ± 0.023	0.488HisMet: 0.488 ± 0.009	0.86HisAsn: 0.86 ± 0.012	1.93HisPro: 1.93 ± 0.022	0.922HisGln: 0.922 ± 0.014	1.512HisArg: 1.512 ± 0.015	2.179HisSer: 2.179 ± 0.021	1.639HisThr: 1.639 ± 0.017	1.603HisVal: 1.603 ± 0.016	0.387HisTrp: 0.387 ± 0.009	0.653HisTyr: 0.653 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.28IleAla: 4.28 ± 0.029	0.688IleCys: 0.688 ± 0.013	2.866IleAsp: 2.866 ± 0.025	2.897IleGlu: 2.897 ± 0.026	1.718IlePhe: 1.718 ± 0.021	3.222IleGly: 3.222 ± 0.027	1.275IleHis: 1.275 ± 0.016	2.533IleIle: 2.533 ± 0.022	2.298IleLys: 2.298 ± 0.02	4.301IleLeu: 4.301 ± 0.033	0.993IleMet: 0.993 ± 0.013	1.821IleAsn: 1.821 ± 0.017	3.322IlePro: 3.322 ± 0.027	1.965IleGln: 1.965 ± 0.021	2.935IleArg: 2.935 ± 0.027	4.053IleSer: 4.053 ± 0.029	2.987IleThr: 2.987 ± 0.023	3.226IleVal: 3.226 ± 0.029	0.78IleTrp: 0.78 ± 0.013	1.413IleTyr: 1.413 ± 0.017	0.001IleXaa: 0.001 ± 0.0
Lys	4.064LysAla: 4.064 ± 0.033	0.541LysCys: 0.541 ± 0.011	2.609LysAsp: 2.609 ± 0.022	3.138LysGlu: 3.138 ± 0.031	1.378LysPhe: 1.378 ± 0.017	2.931LysGly: 2.931 ± 0.029	1.125LysHis: 1.125 ± 0.014	2.227LysIle: 2.227 ± 0.017	2.823LysLys: 2.823 ± 0.034	4.142LysLeu: 4.142 ± 0.032	0.835LysMet: 0.835 ± 0.012	1.62LysAsn: 1.62 ± 0.017	2.829LysPro: 2.829 ± 0.031	1.827LysGln: 1.827 ± 0.017	3.215LysArg: 3.215 ± 0.028	3.585LysSer: 3.585 ± 0.029	2.579LysThr: 2.579 ± 0.022	2.699LysVal: 2.699 ± 0.023	0.754LysTrp: 0.754 ± 0.012	1.281LysTyr: 1.281 ± 0.015	0.001LysXaa: 0.001 ± 0.0
Leu	8.066LeuAla: 8.066 ± 0.045	1.167LeuCys: 1.167 ± 0.014	5.184LeuAsp: 5.184 ± 0.032	5.477LeuGlu: 5.477 ± 0.038	3.21LeuPhe: 3.21 ± 0.029	6.117LeuGly: 6.117 ± 0.043	2.272LeuHis: 2.272 ± 0.02	3.919LeuIle: 3.919 ± 0.028	4.174LeuLys: 4.174 ± 0.028	8.005LeuLeu: 8.005 ± 0.05	1.691LeuMet: 1.691 ± 0.018	3.172LeuAsn: 3.172 ± 0.025	5.96LeuPro: 5.96 ± 0.037	3.356LeuGln: 3.356 ± 0.029	5.61LeuArg: 5.61 ± 0.035	7.617LeuSer: 7.617 ± 0.041	4.962LeuThr: 4.962 ± 0.035	5.79LeuVal: 5.79 ± 0.035	1.144LeuTrp: 1.144 ± 0.015	2.24LeuTyr: 2.24 ± 0.022	0.002LeuXaa: 0.002 ± 0.001
Met	1.838MetAla: 1.838 ± 0.019	0.226MetCys: 0.226 ± 0.006	1.137MetAsp: 1.137 ± 0.015	1.126MetGlu: 1.126 ± 0.013	0.733MetPhe: 0.733 ± 0.012	1.301MetGly: 1.301 ± 0.019	0.502MetHis: 0.502 ± 0.01	0.959MetIle: 0.959 ± 0.014	0.869MetLys: 0.869 ± 0.014	1.807MetLeu: 1.807 ± 0.018	0.515MetMet: 0.515 ± 0.011	0.83MetAsn: 0.83 ± 0.014	1.178MetPro: 1.178 ± 0.015	0.719MetGln: 0.719 ± 0.013	1.278MetArg: 1.278 ± 0.013	2.021MetSer: 2.021 ± 0.02	1.254MetThr: 1.254 ± 0.015	1.186MetVal: 1.186 ± 0.014	0.283MetTrp: 0.283 ± 0.006	0.51MetTyr: 0.51 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.088AsnAla: 3.088 ± 0.026	0.411AsnCys: 0.411 ± 0.01	1.806AsnAsp: 1.806 ± 0.018	1.962AsnGlu: 1.962 ± 0.018	1.219AsnPhe: 1.219 ± 0.014	2.672AsnGly: 2.672 ± 0.027	0.825AsnHis: 0.825 ± 0.012	1.986AsnIle: 1.986 ± 0.019	1.647AsnLys: 1.647 ± 0.017	3.226AsnLeu: 3.226 ± 0.024	0.809AsnMet: 0.809 ± 0.012	1.571AsnAsn: 1.571 ± 0.02	2.571AsnPro: 2.571 ± 0.02	1.357AsnGln: 1.357 ± 0.018	1.885AsnArg: 1.885 ± 0.021	2.969AsnSer: 2.969 ± 0.03	2.304AsnThr: 2.304 ± 0.022	2.429AsnVal: 2.429 ± 0.02	0.545AsnTrp: 0.545 ± 0.01	1.03AsnTyr: 1.03 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	5.666ProAla: 5.666 ± 0.046	0.481ProCys: 0.481 ± 0.01	3.428ProAsp: 3.428 ± 0.028	4.009ProGlu: 4.009 ± 0.03	2.041ProPhe: 2.041 ± 0.019	4.332ProGly: 4.332 ± 0.04	1.634ProHis: 1.634 ± 0.019	3.049ProIle: 3.049 ± 0.024	2.816ProLys: 2.816 ± 0.024	5.183ProLeu: 5.183 ± 0.036	1.116ProMet: 1.116 ± 0.012	2.498ProAsn: 2.498 ± 0.025	6.301ProPro: 6.301 ± 0.082	2.449ProGln: 2.449 ± 0.031	3.777ProArg: 3.777 ± 0.034	6.881ProSer: 6.881 ± 0.06	4.997ProThr: 4.997 ± 0.044	4.076ProVal: 4.076 ± 0.033	0.693ProTrp: 0.693 ± 0.011	1.559ProTyr: 1.559 ± 0.018	0.002ProXaa: 0.002 ± 0.001
Gln	3.405GlnAla: 3.405 ± 0.026	0.434GlnCys: 0.434 ± 0.01	1.903GlnAsp: 1.903 ± 0.017	2.136GlnGlu: 2.136 ± 0.021	1.262GlnPhe: 1.262 ± 0.013	2.225GlnGly: 2.225 ± 0.02	1.023GlnHis: 1.023 ± 0.014	1.821GlnIle: 1.821 ± 0.018	1.558GlnLys: 1.558 ± 0.017	3.529GlnLeu: 3.529 ± 0.026	0.763GlnMet: 0.763 ± 0.011	1.404GlnAsn: 1.404 ± 0.017	2.692GlnPro: 2.692 ± 0.031	1.915GlnGln: 1.915 ± 0.039	2.497GlnArg: 2.497 ± 0.025	3.162GlnSer: 3.162 ± 0.029	2.422GlnThr: 2.422 ± 0.023	2.281GlnVal: 2.281 ± 0.025	0.592GlnTrp: 0.592 ± 0.011	1.104GlnTyr: 1.104 ± 0.017	0.001GlnXaa: 0.001 ± 0.0
Arg	5.391ArgAla: 5.391 ± 0.035	0.713ArgCys: 0.713 ± 0.01	3.183ArgAsp: 3.183 ± 0.032	3.593ArgGlu: 3.593 ± 0.03	2.061ArgPhe: 2.061 ± 0.021	3.693ArgGly: 3.693 ± 0.035	1.481ArgHis: 1.481 ± 0.018	3.107ArgIle: 3.107 ± 0.023	2.989ArgLys: 2.989 ± 0.029	5.51ArgLeu: 5.51 ± 0.035	1.308ArgMet: 1.308 ± 0.015	2.058ArgAsn: 2.058 ± 0.02	3.893ArgPro: 3.893 ± 0.036	2.312ArgGln: 2.312 ± 0.023	4.868ArgArg: 4.868 ± 0.042	5.146ArgSer: 5.146 ± 0.049	3.805ArgThr: 3.805 ± 0.029	3.723ArgVal: 3.723 ± 0.025	0.924ArgTrp: 0.924 ± 0.013	1.589ArgTyr: 1.589 ± 0.022	0.001ArgXaa: 0.001 ± 0.0
Ser	7.008SerAla: 7.008 ± 0.048	0.926SerCys: 0.926 ± 0.014	4.429SerAsp: 4.429 ± 0.038	4.242SerGlu: 4.242 ± 0.036	3.001SerPhe: 3.001 ± 0.021	6.09SerGly: 6.09 ± 0.041	2.17SerHis: 2.17 ± 0.021	4.148SerIle: 4.148 ± 0.027	3.816SerLys: 3.816 ± 0.031	7.347SerLeu: 7.347 ± 0.04	1.677SerMet: 1.677 ± 0.017	3.214SerAsn: 3.214 ± 0.025	6.449SerPro: 6.449 ± 0.063	3.312SerGln: 3.312 ± 0.031	5.464SerArg: 5.464 ± 0.038	9.123SerSer: 9.123 ± 0.07	6.277SerThr: 6.277 ± 0.043	5.266SerVal: 5.266 ± 0.036	1.043SerTrp: 1.043 ± 0.014	2.161SerTyr: 2.161 ± 0.018	0.002SerXaa: 0.002 ± 0.001
Thr	5.052ThrAla: 5.052 ± 0.034	0.754ThrCys: 0.754 ± 0.013	2.804ThrAsp: 2.804 ± 0.022	3.076ThrGlu: 3.076 ± 0.024	2.21ThrPhe: 2.21 ± 0.021	4.468ThrGly: 4.468 ± 0.034	1.547ThrHis: 1.547 ± 0.018	3.306ThrIle: 3.306 ± 0.031	2.708ThrLys: 2.708 ± 0.024	5.571ThrLeu: 5.571 ± 0.033	1.194ThrMet: 1.194 ± 0.012	2.291ThrAsn: 2.291 ± 0.02	5.228ThrPro: 5.228 ± 0.045	2.259ThrGln: 2.259 ± 0.023	3.6ThrArg: 3.6 ± 0.024	5.883ThrSer: 5.883 ± 0.046	4.654ThrThr: 4.654 ± 0.044	3.75ThrVal: 3.75 ± 0.031	0.846ThrTrp: 0.846 ± 0.015	1.627ThrTyr: 1.627 ± 0.02	0.001ThrXaa: 0.001 ± 0.0
Val	5.245ValAla: 5.245 ± 0.037	0.852ValCys: 0.852 ± 0.014	3.542ValAsp: 3.542 ± 0.024	3.605ValGlu: 3.605 ± 0.026	2.382ValPhe: 2.382 ± 0.018	3.928ValGly: 3.928 ± 0.03	1.554ValHis: 1.554 ± 0.016	3.066ValIle: 3.066 ± 0.027	3.02ValLys: 3.02 ± 0.027	5.752ValLeu: 5.752 ± 0.038	1.288ValMet: 1.288 ± 0.016	2.186ValAsn: 2.186 ± 0.023	4.169ValPro: 4.169 ± 0.032	2.444ValGln: 2.444 ± 0.022	3.663ValArg: 3.663 ± 0.027	4.998ValSer: 4.998 ± 0.036	3.584ValThr: 3.584 ± 0.029	4.409ValVal: 4.409 ± 0.032	1.012ValTrp: 1.012 ± 0.015	1.783ValTyr: 1.783 ± 0.016	0.001ValXaa: 0.001 ± 0.0
Trp	1.172TrpAla: 1.172 ± 0.016	0.208TrpCys: 0.208 ± 0.006	0.981TrpAsp: 0.981 ± 0.018	0.841TrpGlu: 0.841 ± 0.012	0.53TrpPhe: 0.53 ± 0.009	0.928TrpGly: 0.928 ± 0.014	0.392TrpHis: 0.392 ± 0.008	0.733TrpIle: 0.733 ± 0.012	0.854TrpLys: 0.854 ± 0.012	1.314TrpLeu: 1.314 ± 0.016	0.386TrpMet: 0.386 ± 0.01	0.673TrpAsn: 0.673 ± 0.011	0.637TrpPro: 0.637 ± 0.011	0.489TrpGln: 0.489 ± 0.009	0.908TrpArg: 0.908 ± 0.012	1.153TrpSer: 1.153 ± 0.015	0.887TrpThr: 0.887 ± 0.014	0.894TrpVal: 0.894 ± 0.013	0.262TrpTrp: 0.262 ± 0.008	0.389TrpTyr: 0.389 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.194TyrAla: 2.194 ± 0.021	0.354TyrCys: 0.354 ± 0.009	1.665TyrAsp: 1.665 ± 0.02	1.413TyrGlu: 1.413 ± 0.017	1.063TyrPhe: 1.063 ± 0.014	1.964TyrGly: 1.964 ± 0.021	0.715TyrHis: 0.715 ± 0.011	1.408TyrIle: 1.408 ± 0.018	1.073TyrLys: 1.073 ± 0.016	2.515TyrLeu: 2.515 ± 0.024	0.584TyrMet: 0.584 ± 0.01	1.129TyrAsn: 1.129 ± 0.014	1.494TyrPro: 1.494 ± 0.018	1.065TyrGln: 1.065 ± 0.016	1.532TyrArg: 1.532 ± 0.018	2.172TyrSer: 2.172 ± 0.021	1.632TyrThr: 1.632 ± 0.019	1.714TyrVal: 1.714 ± 0.021	0.457TyrTrp: 0.457 ± 0.009	0.845TyrTyr: 0.845 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.002XaaLeu: 0.002 ± 0.001	0.001XaaMet: 0.001 ± 0.0	0.001XaaAsn: 0.001 ± 0.001	0.002XaaPro: 0.002 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.002XaaArg: 0.002 ± 0.001	0.003XaaSer: 0.003 ± 0.001	0.001XaaThr: 0.001 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.001XaaTrp: 0.001 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.298XaaXaa: 0.298 ± 0.067

Statistics based on 12613 proteins (5771931 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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