Amino acid dipepetide frequency for Dictyobacter kobayashii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.221AlaAla: 9.221 ± 0.079	1.024AlaCys: 1.024 ± 0.022	4.224AlaAsp: 4.224 ± 0.044	5.181AlaGlu: 5.181 ± 0.062	3.428AlaPhe: 3.428 ± 0.037	6.644AlaGly: 6.644 ± 0.051	2.388AlaHis: 2.388 ± 0.035	5.967AlaIle: 5.967 ± 0.06	2.463AlaLys: 2.463 ± 0.033	11.268AlaLeu: 11.268 ± 0.081	2.296AlaMet: 2.296 ± 0.033	3.113AlaAsn: 3.113 ± 0.043	3.99AlaPro: 3.99 ± 0.043	4.934AlaGln: 4.934 ± 0.054	5.917AlaArg: 5.917 ± 0.048	5.773AlaSer: 5.773 ± 0.056	5.619AlaThr: 5.619 ± 0.059	5.893AlaVal: 5.893 ± 0.066	1.352AlaTrp: 1.352 ± 0.026	2.82AlaTyr: 2.82 ± 0.037	0.0AlaXaa: 0.0 ± 0.0
Cys	0.845CysAla: 0.845 ± 0.019	0.163CysCys: 0.163 ± 0.009	0.482CysAsp: 0.482 ± 0.015	0.473CysGlu: 0.473 ± 0.014	0.367CysPhe: 0.367 ± 0.013	0.892CysGly: 0.892 ± 0.021	0.283CysHis: 0.283 ± 0.012	0.626CysIle: 0.626 ± 0.016	0.268CysLys: 0.268 ± 0.01	1.024CysLeu: 1.024 ± 0.022	0.237CysMet: 0.237 ± 0.01	0.315CysAsn: 0.315 ± 0.013	0.524CysPro: 0.524 ± 0.017	0.492CysGln: 0.492 ± 0.015	0.508CysArg: 0.508 ± 0.015	0.669CysSer: 0.669 ± 0.016	0.552CysThr: 0.552 ± 0.015	0.626CysVal: 0.626 ± 0.015	0.187CysTrp: 0.187 ± 0.008	0.357CysTyr: 0.357 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	4.348AspAla: 4.348 ± 0.042	0.403AspCys: 0.403 ± 0.014	2.215AspAsp: 2.215 ± 0.034	3.258AspGlu: 3.258 ± 0.049	1.828AspPhe: 1.828 ± 0.027	3.546AspGly: 3.546 ± 0.048	1.134AspHis: 1.134 ± 0.023	3.159AspIle: 3.159 ± 0.039	1.58AspLys: 1.58 ± 0.027	5.012AspLeu: 5.012 ± 0.055	1.162AspMet: 1.162 ± 0.022	1.625AspAsn: 1.625 ± 0.029	2.884AspPro: 2.884 ± 0.036	2.279AspGln: 2.279 ± 0.033	2.466AspArg: 2.466 ± 0.037	2.248AspSer: 2.248 ± 0.033	2.739AspThr: 2.739 ± 0.035	3.371AspVal: 3.371 ± 0.038	0.802AspTrp: 0.802 ± 0.02	1.62AspTyr: 1.62 ± 0.026	0.0AspXaa: 0.0 ± 0.0
Glu	5.59GluAla: 5.59 ± 0.065	0.389GluCys: 0.389 ± 0.014	2.627GluAsp: 2.627 ± 0.033	4.116GluGlu: 4.116 ± 0.059	1.463GluPhe: 1.463 ± 0.027	3.179GluGly: 3.179 ± 0.042	1.784GluHis: 1.784 ± 0.029	3.348GluIle: 3.348 ± 0.045	2.421GluLys: 2.421 ± 0.036	5.94GluLeu: 5.94 ± 0.059	1.408GluMet: 1.408 ± 0.027	1.78GluAsn: 1.78 ± 0.031	2.42GluPro: 2.42 ± 0.035	4.43GluGln: 4.43 ± 0.055	4.403GluArg: 4.403 ± 0.057	2.465GluSer: 2.465 ± 0.036	3.013GluThr: 3.013 ± 0.036	3.777GluVal: 3.777 ± 0.042	0.69GluTrp: 0.69 ± 0.016	1.552GluTyr: 1.552 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	3.306PheAla: 3.306 ± 0.041	0.479PheCys: 0.479 ± 0.015	1.935PheAsp: 1.935 ± 0.029	1.867PheGlu: 1.867 ± 0.03	1.739PhePhe: 1.739 ± 0.034	2.823PheGly: 2.823 ± 0.038	0.901PheHis: 0.901 ± 0.02	2.214PheIle: 2.214 ± 0.031	1.097PheLys: 1.097 ± 0.024	3.893PheLeu: 3.893 ± 0.05	0.809PheMet: 0.809 ± 0.018	1.309PheAsn: 1.309 ± 0.025	1.687PhePro: 1.687 ± 0.026	1.529PheGln: 1.529 ± 0.027	1.676PheArg: 1.676 ± 0.029	2.631PheSer: 2.631 ± 0.034	2.27PheThr: 2.27 ± 0.03	2.514PheVal: 2.514 ± 0.031	0.635PheTrp: 0.635 ± 0.019	1.255PheTyr: 1.255 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	5.737GlyAla: 5.737 ± 0.058	0.774GlyCys: 0.774 ± 0.017	3.002GlyAsp: 3.002 ± 0.037	3.575GlyGlu: 3.575 ± 0.047	2.634GlyPhe: 2.634 ± 0.035	5.19GlyGly: 5.19 ± 0.078	1.806GlyHis: 1.806 ± 0.028	4.638GlyIle: 4.638 ± 0.049	3.131GlyLys: 3.131 ± 0.042	7.197GlyLeu: 7.197 ± 0.063	1.844GlyMet: 1.844 ± 0.027	2.616GlyAsn: 2.616 ± 0.04	2.705GlyPro: 2.705 ± 0.035	3.448GlyGln: 3.448 ± 0.047	3.858GlyArg: 3.858 ± 0.049	4.71GlySer: 4.71 ± 0.055	4.358GlyThr: 4.358 ± 0.056	4.764GlyVal: 4.764 ± 0.054	1.256GlyTrp: 1.256 ± 0.032	2.636GlyTyr: 2.636 ± 0.038	0.0GlyXaa: 0.0 ± 0.0
His	2.155HisAla: 2.155 ± 0.029	0.291HisCys: 0.291 ± 0.01	1.191HisAsp: 1.191 ± 0.022	1.428HisGlu: 1.428 ± 0.027	1.047HisPhe: 1.047 ± 0.024	1.827HisGly: 1.827 ± 0.032	0.763HisHis: 0.763 ± 0.021	1.719HisIle: 1.719 ± 0.028	0.788HisLys: 0.788 ± 0.019	2.795HisLeu: 2.795 ± 0.039	0.666HisMet: 0.666 ± 0.016	0.899HisAsn: 0.899 ± 0.019	1.618HisPro: 1.618 ± 0.028	1.184HisGln: 1.184 ± 0.023	1.266HisArg: 1.266 ± 0.024	1.483HisSer: 1.483 ± 0.026	1.605HisThr: 1.605 ± 0.03	1.672HisVal: 1.672 ± 0.029	0.478HisTrp: 0.478 ± 0.015	0.935HisTyr: 0.935 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	6.226IleAla: 6.226 ± 0.057	0.714IleCys: 0.714 ± 0.016	3.196IleAsp: 3.196 ± 0.037	3.694IleGlu: 3.694 ± 0.052	2.407IlePhe: 2.407 ± 0.039	4.43IleGly: 4.43 ± 0.051	1.494IleHis: 1.494 ± 0.028	3.773IleIle: 3.773 ± 0.047	1.97IleLys: 1.97 ± 0.035	6.123IleLeu: 6.123 ± 0.051	1.226IleMet: 1.226 ± 0.021	2.237IleAsn: 2.237 ± 0.033	3.127IlePro: 3.127 ± 0.039	2.695IleGln: 2.695 ± 0.04	2.866IleArg: 2.866 ± 0.035	4.01IleSer: 4.01 ± 0.04	3.543IleThr: 3.543 ± 0.044	4.39IleVal: 4.39 ± 0.045	0.879IleTrp: 0.879 ± 0.022	1.891IleTyr: 1.891 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	3.031LysAla: 3.031 ± 0.035	0.209LysCys: 0.209 ± 0.01	1.74LysAsp: 1.74 ± 0.034	2.178LysGlu: 2.178 ± 0.037	0.84LysPhe: 0.84 ± 0.02	2.158LysGly: 2.158 ± 0.034	0.902LysHis: 0.902 ± 0.021	1.887LysIle: 1.887 ± 0.033	1.692LysLys: 1.692 ± 0.037	3.282LysLeu: 3.282 ± 0.04	0.884LysMet: 0.884 ± 0.017	1.326LysAsn: 1.326 ± 0.027	1.719LysPro: 1.719 ± 0.027	2.074LysGln: 2.074 ± 0.031	2.35LysArg: 2.35 ± 0.035	1.811LysSer: 1.811 ± 0.029	2.008LysThr: 2.008 ± 0.027	2.241LysVal: 2.241 ± 0.028	0.376LysTrp: 0.376 ± 0.014	1.003LysTyr: 1.003 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	11.15LeuAla: 11.15 ± 0.081	1.229LeuCys: 1.229 ± 0.022	5.207LeuAsp: 5.207 ± 0.047	5.766LeuGlu: 5.766 ± 0.062	4.159LeuPhe: 4.159 ± 0.055	7.213LeuGly: 7.213 ± 0.059	2.727LeuHis: 2.727 ± 0.039	6.192LeuIle: 6.192 ± 0.059	3.654LeuLys: 3.654 ± 0.039	13.326LeuLeu: 13.326 ± 0.142	2.212LeuMet: 2.212 ± 0.03	3.587LeuAsn: 3.587 ± 0.041	6.009LeuPro: 6.009 ± 0.053	5.551LeuGln: 5.551 ± 0.056	6.446LeuArg: 6.446 ± 0.065	7.263LeuSer: 7.263 ± 0.063	6.247LeuThr: 6.247 ± 0.057	7.196LeuVal: 7.196 ± 0.069	1.465LeuTrp: 1.465 ± 0.027	3.159LeuTyr: 3.159 ± 0.045	0.0LeuXaa: 0.0 ± 0.0
Met	2.293MetAla: 2.293 ± 0.033	0.166MetCys: 0.166 ± 0.008	1.09MetAsp: 1.09 ± 0.023	1.156MetGlu: 1.156 ± 0.021	0.697MetPhe: 0.697 ± 0.017	1.592MetGly: 1.592 ± 0.026	0.633MetHis: 0.633 ± 0.016	1.288MetIle: 1.288 ± 0.024	0.851MetLys: 0.851 ± 0.02	2.752MetLeu: 2.752 ± 0.038	0.543MetMet: 0.543 ± 0.016	0.816MetAsn: 0.816 ± 0.018	1.28MetPro: 1.28 ± 0.025	1.289MetGln: 1.289 ± 0.025	1.564MetArg: 1.564 ± 0.027	1.545MetSer: 1.545 ± 0.026	1.381MetThr: 1.381 ± 0.026	1.599MetVal: 1.599 ± 0.027	0.216MetTrp: 0.216 ± 0.009	0.537MetTyr: 0.537 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.226AsnAla: 3.226 ± 0.036	0.319AsnCys: 0.319 ± 0.014	1.708AsnAsp: 1.708 ± 0.027	1.821AsnGlu: 1.821 ± 0.029	1.226AsnPhe: 1.226 ± 0.023	2.76AsnGly: 2.76 ± 0.039	0.779AsnHis: 0.779 ± 0.017	2.313AsnIle: 2.313 ± 0.033	1.215AsnLys: 1.215 ± 0.024	3.396AsnLeu: 3.396 ± 0.034	0.811AsnMet: 0.811 ± 0.019	1.583AsnAsn: 1.583 ± 0.034	2.062AsnPro: 2.062 ± 0.027	1.665AsnGln: 1.665 ± 0.029	1.667AsnArg: 1.667 ± 0.028	2.071AsnSer: 2.071 ± 0.034	2.176AsnThr: 2.176 ± 0.034	2.319AsnVal: 2.319 ± 0.038	0.619AsnTrp: 0.619 ± 0.017	1.221AsnTyr: 1.221 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	5.072ProAla: 5.072 ± 0.058	0.367ProCys: 0.367 ± 0.013	3.015ProAsp: 3.015 ± 0.04	3.47ProGlu: 3.47 ± 0.044	1.998ProPhe: 1.998 ± 0.026	3.783ProGly: 3.783 ± 0.046	1.225ProHis: 1.225 ± 0.025	2.725ProIle: 2.725 ± 0.038	1.333ProLys: 1.333 ± 0.024	5.424ProLeu: 5.424 ± 0.052	1.035ProMet: 1.035 ± 0.023	1.676ProAsn: 1.676 ± 0.031	2.448ProPro: 2.448 ± 0.048	2.513ProGln: 2.513 ± 0.038	2.47ProArg: 2.47 ± 0.037	2.934ProSer: 2.934 ± 0.043	3.453ProThr: 3.453 ± 0.048	3.551ProVal: 3.551 ± 0.046	0.769ProTrp: 0.769 ± 0.019	1.595ProTyr: 1.595 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	5.586GlnAla: 5.586 ± 0.059	0.367GlnCys: 0.367 ± 0.013	2.156GlnAsp: 2.156 ± 0.032	3.19GlnGlu: 3.19 ± 0.045	1.476GlnPhe: 1.476 ± 0.023	3.367GlnGly: 3.367 ± 0.039	1.589GlnHis: 1.589 ± 0.028	2.738GlnIle: 2.738 ± 0.036	2.046GlnLys: 2.046 ± 0.032	5.615GlnLeu: 5.615 ± 0.061	1.149GlnMet: 1.149 ± 0.022	1.617GlnAsn: 1.617 ± 0.03	2.922GlnPro: 2.922 ± 0.046	4.037GlnGln: 4.037 ± 0.062	3.739GlnArg: 3.739 ± 0.041	2.903GlnSer: 2.903 ± 0.041	2.883GlnThr: 2.883 ± 0.037	3.408GlnVal: 3.408 ± 0.041	0.727GlnTrp: 0.727 ± 0.02	1.391GlnTyr: 1.391 ± 0.025	0.0GlnXaa: 0.0 ± 0.0
Arg	4.93ArgAla: 4.93 ± 0.045	0.591ArgCys: 0.591 ± 0.016	2.589ArgAsp: 2.589 ± 0.039	3.676ArgGlu: 3.676 ± 0.047	2.258ArgPhe: 2.258 ± 0.035	3.407ArgGly: 3.407 ± 0.038	1.484ArgHis: 1.484 ± 0.022	3.532ArgIle: 3.532 ± 0.039	2.141ArgLys: 2.141 ± 0.036	6.551ArgLeu: 6.551 ± 0.064	1.521ArgMet: 1.521 ± 0.026	1.869ArgAsn: 1.869 ± 0.028	2.748ArgPro: 2.748 ± 0.031	3.377ArgGln: 3.377 ± 0.043	4.107ArgArg: 4.107 ± 0.05	3.496ArgSer: 3.496 ± 0.039	3.072ArgThr: 3.072 ± 0.038	3.767ArgVal: 3.767 ± 0.044	1.064ArgTrp: 1.064 ± 0.024	2.171ArgTyr: 2.171 ± 0.032	0.0ArgXaa: 0.0 ± 0.0
Ser	5.356SerAla: 5.356 ± 0.052	0.595SerCys: 0.595 ± 0.016	2.992SerAsp: 2.992 ± 0.04	3.087SerGlu: 3.087 ± 0.039	2.473SerPhe: 2.473 ± 0.032	4.752SerGly: 4.752 ± 0.06	1.506SerHis: 1.506 ± 0.027	3.878SerIle: 3.878 ± 0.04	1.889SerLys: 1.889 ± 0.029	6.593SerLeu: 6.593 ± 0.062	1.591SerMet: 1.591 ± 0.027	2.318SerAsn: 2.318 ± 0.038	3.164SerPro: 3.164 ± 0.046	2.866SerGln: 2.866 ± 0.037	3.122SerArg: 3.122 ± 0.035	4.547SerSer: 4.547 ± 0.058	3.907SerThr: 3.907 ± 0.044	3.813SerVal: 3.813 ± 0.042	1.14SerTrp: 1.14 ± 0.026	2.11SerTyr: 2.11 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	5.102ThrAla: 5.102 ± 0.054	0.585ThrCys: 0.585 ± 0.016	2.612ThrAsp: 2.612 ± 0.033	2.638ThrGlu: 2.638 ± 0.037	2.433ThrPhe: 2.433 ± 0.036	4.441ThrGly: 4.441 ± 0.05	1.523ThrHis: 1.523 ± 0.029	4.12ThrIle: 4.12 ± 0.046	1.548ThrLys: 1.548 ± 0.03	6.782ThrLeu: 6.782 ± 0.065	1.266ThrMet: 1.266 ± 0.022	2.164ThrAsn: 2.164 ± 0.03	3.847ThrPro: 3.847 ± 0.054	2.692ThrGln: 2.692 ± 0.035	3.141ThrArg: 3.141 ± 0.04	3.833ThrSer: 3.833 ± 0.045	4.085ThrThr: 4.085 ± 0.052	3.986ThrVal: 3.986 ± 0.046	0.817ThrTrp: 0.817 ± 0.02	1.951ThrTyr: 1.951 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	6.567ValAla: 6.567 ± 0.056	0.676ValCys: 0.676 ± 0.017	3.321ValAsp: 3.321 ± 0.036	3.777ValGlu: 3.777 ± 0.045	2.362ValPhe: 2.362 ± 0.033	4.678ValGly: 4.678 ± 0.049	1.518ValHis: 1.518 ± 0.027	4.154ValIle: 4.154 ± 0.049	2.151ValLys: 2.151 ± 0.034	7.389ValLeu: 7.389 ± 0.064	1.56ValMet: 1.56 ± 0.028	2.261ValAsn: 2.261 ± 0.035	3.43ValPro: 3.43 ± 0.037	3.033ValGln: 3.033 ± 0.035	3.78ValArg: 3.78 ± 0.044	4.257ValSer: 4.257 ± 0.05	3.964ValThr: 3.964 ± 0.042	5.111ValVal: 5.111 ± 0.057	0.856ValTrp: 0.856 ± 0.017	2.019ValTyr: 2.019 ± 0.081	0.0ValXaa: 0.0 ± 0.0
Trp	0.999TrpAla: 0.999 ± 0.023	0.169TrpCys: 0.169 ± 0.009	0.686TrpAsp: 0.686 ± 0.017	0.76TrpGlu: 0.76 ± 0.017	0.566TrpPhe: 0.566 ± 0.018	0.922TrpGly: 0.922 ± 0.023	0.467TrpHis: 0.467 ± 0.016	0.85TrpIle: 0.85 ± 0.02	0.562TrpLys: 0.562 ± 0.018	1.979TrpLeu: 1.979 ± 0.035	0.405TrpMet: 0.405 ± 0.013	0.645TrpAsn: 0.645 ± 0.017	0.684TrpPro: 0.684 ± 0.017	0.995TrpGln: 0.995 ± 0.024	0.99TrpArg: 0.99 ± 0.021	1.165TrpSer: 1.165 ± 0.026	0.775TrpThr: 0.775 ± 0.017	0.787TrpVal: 0.787 ± 0.02	0.299TrpTrp: 0.299 ± 0.012	0.471TrpTyr: 0.471 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.774TyrAla: 2.774 ± 0.037	0.382TyrCys: 0.382 ± 0.012	1.691TyrAsp: 1.691 ± 0.043	1.682TyrGlu: 1.682 ± 0.028	1.171TyrPhe: 1.171 ± 0.025	2.275TyrGly: 2.275 ± 0.036	0.903TyrHis: 0.903 ± 0.019	1.771TyrIle: 1.771 ± 0.027	0.908TyrLys: 0.908 ± 0.019	3.417TyrLeu: 3.417 ± 0.037	0.663TyrMet: 0.663 ± 0.018	1.201TyrAsn: 1.201 ± 0.023	1.586TyrPro: 1.586 ± 0.03	1.826TyrGln: 1.826 ± 0.029	2.017TyrArg: 2.017 ± 0.03	1.885TyrSer: 1.885 ± 0.028	1.918TyrThr: 1.918 ± 0.028	2.08TyrVal: 2.08 ± 0.081	0.546TyrTrp: 0.546 ± 0.016	1.148TyrTyr: 1.148 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8237 proteins (2351450 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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