Amino acid dipepetide frequency for Fowl aviadenovirus 6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.437AlaAla: 8.437 ± 1.719
1.006AlaCys: 1.006 ± 0.376
3.715AlaAsp: 3.715 ± 0.412
5.496AlaGlu: 5.496 ± 0.762
2.787AlaPhe: 2.787 ± 0.365
4.877AlaGly: 4.877 ± 0.659
1.316AlaHis: 1.316 ± 0.239
3.793AlaIle: 3.793 ± 0.617
3.096AlaLys: 3.096 ± 0.667
8.128AlaLeu: 8.128 ± 0.837
1.471AlaMet: 1.471 ± 0.462
3.174AlaAsn: 3.174 ± 0.393
6.812AlaPro: 6.812 ± 0.838
3.096AlaGln: 3.096 ± 0.58
4.025AlaArg: 4.025 ± 0.703
5.805AlaSer: 5.805 ± 0.655
4.644AlaThr: 4.644 ± 0.688
6.966AlaVal: 6.966 ± 0.752
0.851AlaTrp: 0.851 ± 0.278
3.251AlaTyr: 3.251 ± 0.484
0.0AlaXaa: 0.0 ± 0.0
Cys
0.851CysAla: 0.851 ± 0.233
0.232CysCys: 0.232 ± 0.12
1.006CysAsp: 1.006 ± 0.279
0.542CysGlu: 0.542 ± 0.237
0.851CysPhe: 0.851 ± 0.229
1.703CysGly: 1.703 ± 0.422
0.619CysHis: 0.619 ± 0.29
0.464CysIle: 0.464 ± 0.173
0.619CysLys: 0.619 ± 0.24
1.626CysLeu: 1.626 ± 0.366
0.542CysMet: 0.542 ± 0.18
0.851CysAsn: 0.851 ± 0.253
1.393CysPro: 1.393 ± 0.353
0.774CysGln: 0.774 ± 0.288
1.393CysArg: 1.393 ± 0.284
1.548CysSer: 1.548 ± 0.327
0.929CysThr: 0.929 ± 0.278
1.238CysVal: 1.238 ± 0.371
0.387CysTrp: 0.387 ± 0.166
0.697CysTyr: 0.697 ± 0.224
0.0CysXaa: 0.0 ± 0.0
Asp
4.644AspAla: 4.644 ± 0.576
0.464AspCys: 0.464 ± 0.173
3.483AspAsp: 3.483 ± 0.691
3.715AspGlu: 3.715 ± 0.8
2.787AspPhe: 2.787 ± 0.586
4.722AspGly: 4.722 ± 0.629
1.238AspHis: 1.238 ± 0.214
2.632AspIle: 2.632 ± 0.453
1.393AspLys: 1.393 ± 0.28
5.109AspLeu: 5.109 ± 0.552
0.851AspMet: 0.851 ± 0.212
1.703AspAsn: 1.703 ± 0.526
5.186AspPro: 5.186 ± 0.897
2.167AspGln: 2.167 ± 0.349
4.18AspArg: 4.18 ± 0.448
4.257AspSer: 4.257 ± 0.411
3.174AspThr: 3.174 ± 0.477
2.554AspVal: 2.554 ± 0.417
0.464AspTrp: 0.464 ± 0.162
2.322AspTyr: 2.322 ± 0.28
0.0AspXaa: 0.0 ± 0.0
Glu
4.18GluAla: 4.18 ± 0.578
0.774GluCys: 0.774 ± 0.227
4.102GluAsp: 4.102 ± 0.674
8.979GluGlu: 8.979 ± 1.731
1.626GluPhe: 1.626 ± 0.381
3.406GluGly: 3.406 ± 0.542
1.548GluHis: 1.548 ± 0.399
2.09GluIle: 2.09 ± 0.286
2.632GluLys: 2.632 ± 0.568
5.418GluLeu: 5.418 ± 0.592
1.316GluMet: 1.316 ± 0.326
2.941GluAsn: 2.941 ± 0.401
2.787GluPro: 2.787 ± 0.481
2.245GluGln: 2.245 ± 0.44
4.102GluArg: 4.102 ± 0.542
4.257GluSer: 4.257 ± 0.54
2.864GluThr: 2.864 ± 0.401
3.328GluVal: 3.328 ± 0.462
0.851GluTrp: 0.851 ± 0.218
1.548GluTyr: 1.548 ± 0.292
0.0GluXaa: 0.0 ± 0.0
Phe
3.096PheAla: 3.096 ± 0.466
0.464PheCys: 0.464 ± 0.217
2.554PheAsp: 2.554 ± 0.602
2.322PheGlu: 2.322 ± 0.367
1.858PhePhe: 1.858 ± 0.279
1.78PheGly: 1.78 ± 0.391
1.78PheHis: 1.78 ± 0.343
1.084PheIle: 1.084 ± 0.285
1.548PheLys: 1.548 ± 0.298
3.948PheLeu: 3.948 ± 0.619
1.238PheMet: 1.238 ± 0.345
2.245PheAsn: 2.245 ± 0.337
2.4PhePro: 2.4 ± 0.47
0.542PheGln: 0.542 ± 0.177
3.483PheArg: 3.483 ± 0.495
2.4PheSer: 2.4 ± 0.486
2.477PheThr: 2.477 ± 0.4
3.483PheVal: 3.483 ± 0.442
1.006PheTrp: 1.006 ± 0.288
1.78PheTyr: 1.78 ± 0.304
0.0PheXaa: 0.0 ± 0.0
Gly
6.27GlyAla: 6.27 ± 0.731
0.929GlyCys: 0.929 ± 0.253
3.948GlyAsp: 3.948 ± 0.482
3.948GlyGlu: 3.948 ± 0.789
2.013GlyPhe: 2.013 ± 0.286
6.812GlyGly: 6.812 ± 1.089
1.316GlyHis: 1.316 ± 0.409
2.477GlyIle: 2.477 ± 0.44
1.78GlyLys: 1.78 ± 0.337
3.87GlyLeu: 3.87 ± 0.52
1.548GlyMet: 1.548 ± 0.36
2.013GlyAsn: 2.013 ± 0.423
3.251GlyPro: 3.251 ± 0.501
2.09GlyGln: 2.09 ± 0.384
4.49GlyArg: 4.49 ± 0.581
5.186GlySer: 5.186 ± 0.675
3.87GlyThr: 3.87 ± 0.542
4.335GlyVal: 4.335 ± 0.703
1.006GlyTrp: 1.006 ± 0.179
2.632GlyTyr: 2.632 ± 0.61
0.0GlyXaa: 0.0 ± 0.0
His
1.703HisAla: 1.703 ± 0.289
0.619HisCys: 0.619 ± 0.285
1.084HisAsp: 1.084 ± 0.257
0.929HisGlu: 0.929 ± 0.245
0.929HisPhe: 0.929 ± 0.285
1.548HisGly: 1.548 ± 0.349
1.161HisHis: 1.161 ± 0.23
1.238HisIle: 1.238 ± 0.298
0.542HisLys: 0.542 ± 0.159
1.626HisLeu: 1.626 ± 0.346
0.542HisMet: 0.542 ± 0.181
1.161HisAsn: 1.161 ± 0.254
1.393HisPro: 1.393 ± 0.445
0.929HisGln: 0.929 ± 0.362
2.322HisArg: 2.322 ± 0.472
1.006HisSer: 1.006 ± 0.29
1.548HisThr: 1.548 ± 0.292
1.626HisVal: 1.626 ± 0.34
0.31HisTrp: 0.31 ± 0.136
1.161HisTyr: 1.161 ± 0.256
0.0HisXaa: 0.0 ± 0.0
Ile
3.561IleAla: 3.561 ± 0.606
0.774IleCys: 0.774 ± 0.279
1.703IleAsp: 1.703 ± 0.326
1.393IleGlu: 1.393 ± 0.225
1.238IlePhe: 1.238 ± 0.333
2.554IleGly: 2.554 ± 0.416
0.697IleHis: 0.697 ± 0.243
1.316IleIle: 1.316 ± 0.39
1.703IleLys: 1.703 ± 0.332
3.174IleLeu: 3.174 ± 0.51
0.077IleMet: 0.077 ± 0.074
1.548IleAsn: 1.548 ± 0.434
3.096IlePro: 3.096 ± 0.471
1.084IleGln: 1.084 ± 0.23
2.632IleArg: 2.632 ± 0.421
2.167IleSer: 2.167 ± 0.337
2.477IleThr: 2.477 ± 0.631
2.554IleVal: 2.554 ± 0.379
0.542IleTrp: 0.542 ± 0.192
1.471IleTyr: 1.471 ± 0.292
0.0IleXaa: 0.0 ± 0.0
Lys
3.019LysAla: 3.019 ± 0.606
0.619LysCys: 0.619 ± 0.158
1.703LysAsp: 1.703 ± 0.434
2.09LysGlu: 2.09 ± 0.351
1.548LysPhe: 1.548 ± 0.324
2.013LysGly: 2.013 ± 0.468
0.31LysHis: 0.31 ± 0.143
1.084LysIle: 1.084 ± 0.256
1.703LysLys: 1.703 ± 0.634
3.019LysLeu: 3.019 ± 0.461
0.929LysMet: 0.929 ± 0.273
1.471LysAsn: 1.471 ± 0.366
1.703LysPro: 1.703 ± 0.446
0.929LysGln: 0.929 ± 0.298
4.412LysArg: 4.412 ± 0.836
1.548LysSer: 1.548 ± 0.312
2.245LysThr: 2.245 ± 0.455
2.167LysVal: 2.167 ± 0.489
0.387LysTrp: 0.387 ± 0.161
1.703LysTyr: 1.703 ± 0.408
0.0LysXaa: 0.0 ± 0.0
Leu
7.276LeuAla: 7.276 ± 0.634
2.477LeuCys: 2.477 ± 0.458
5.031LeuAsp: 5.031 ± 0.595
4.49LeuGlu: 4.49 ± 0.485
4.102LeuPhe: 4.102 ± 0.499
4.257LeuGly: 4.257 ± 0.598
2.322LeuHis: 2.322 ± 0.604
2.4LeuIle: 2.4 ± 0.397
3.793LeuLys: 3.793 ± 0.592
8.669LeuLeu: 8.669 ± 1.114
1.858LeuMet: 1.858 ± 0.35
4.025LeuAsn: 4.025 ± 0.463
5.418LeuPro: 5.418 ± 0.571
4.335LeuGln: 4.335 ± 0.548
6.812LeuArg: 6.812 ± 0.858
6.192LeuSer: 6.192 ± 0.611
6.579LeuThr: 6.579 ± 0.72
4.799LeuVal: 4.799 ± 0.702
1.626LeuTrp: 1.626 ± 0.286
3.483LeuTyr: 3.483 ± 0.375
0.0LeuXaa: 0.0 ± 0.0
Met
2.245MetAla: 2.245 ± 0.431
0.232MetCys: 0.232 ± 0.126
1.238MetAsp: 1.238 ± 0.303
0.929MetGlu: 0.929 ± 0.296
1.084MetPhe: 1.084 ± 0.246
1.316MetGly: 1.316 ± 0.405
0.774MetHis: 0.774 ± 0.197
0.851MetIle: 0.851 ± 0.272
0.774MetLys: 0.774 ± 0.233
2.245MetLeu: 2.245 ± 0.385
0.464MetMet: 0.464 ± 0.175
0.619MetAsn: 0.619 ± 0.192
1.238MetPro: 1.238 ± 0.28
0.774MetGln: 0.774 ± 0.244
2.013MetArg: 2.013 ± 0.422
1.78MetSer: 1.78 ± 0.367
1.393MetThr: 1.393 ± 0.308
1.78MetVal: 1.78 ± 0.358
0.077MetTrp: 0.077 ± 0.055
0.929MetTyr: 0.929 ± 0.311
0.0MetXaa: 0.0 ± 0.0
Asn
3.483AsnAla: 3.483 ± 0.51
0.697AsnCys: 0.697 ± 0.204
2.632AsnAsp: 2.632 ± 0.403
1.316AsnGlu: 1.316 ± 0.42
1.703AsnPhe: 1.703 ± 0.44
1.78AsnGly: 1.78 ± 0.516
0.851AsnHis: 0.851 ± 0.195
1.548AsnIle: 1.548 ± 0.532
1.006AsnLys: 1.006 ± 0.259
3.174AsnLeu: 3.174 ± 0.598
0.697AsnMet: 0.697 ± 0.263
1.626AsnAsn: 1.626 ± 0.422
3.87AsnPro: 3.87 ± 0.536
1.084AsnGln: 1.084 ± 0.32
2.477AsnArg: 2.477 ± 0.44
2.941AsnSer: 2.941 ± 0.587
2.4AsnThr: 2.4 ± 0.478
3.096AsnVal: 3.096 ± 0.532
0.929AsnTrp: 0.929 ± 0.309
1.858AsnTyr: 1.858 ± 0.518
0.0AsnXaa: 0.0 ± 0.0
Pro
6.502ProAla: 6.502 ± 0.89
0.929ProCys: 0.929 ± 0.269
3.793ProAsp: 3.793 ± 0.538
4.954ProGlu: 4.954 ± 0.72
3.096ProPhe: 3.096 ± 0.599
3.561ProGly: 3.561 ± 0.364
1.858ProHis: 1.858 ± 0.27
1.858ProIle: 1.858 ± 0.413
2.4ProLys: 2.4 ± 0.497
5.496ProLeu: 5.496 ± 0.598
1.703ProMet: 1.703 ± 0.351
2.4ProAsn: 2.4 ± 0.456
8.437ProPro: 8.437 ± 1.208
2.013ProGln: 2.013 ± 0.598
3.948ProArg: 3.948 ± 0.466
5.496ProSer: 5.496 ± 0.62
4.102ProThr: 4.102 ± 0.52
4.567ProVal: 4.567 ± 0.642
0.387ProTrp: 0.387 ± 0.188
2.864ProTyr: 2.864 ± 0.425
0.0ProXaa: 0.0 ± 0.0
Gln
2.632GlnAla: 2.632 ± 0.524
0.31GlnCys: 0.31 ± 0.14
1.935GlnAsp: 1.935 ± 0.307
1.935GlnGlu: 1.935 ± 0.328
1.316GlnPhe: 1.316 ± 0.351
1.935GlnGly: 1.935 ± 0.323
0.697GlnHis: 0.697 ± 0.316
1.238GlnIle: 1.238 ± 0.316
1.393GlnLys: 1.393 ± 0.3
3.87GlnLeu: 3.87 ± 0.524
1.316GlnMet: 1.316 ± 0.384
1.858GlnAsn: 1.858 ± 0.532
1.858GlnPro: 1.858 ± 0.363
3.174GlnGln: 3.174 ± 1.204
2.864GlnArg: 2.864 ± 0.507
2.245GlnSer: 2.245 ± 0.446
2.554GlnThr: 2.554 ± 0.469
1.935GlnVal: 1.935 ± 0.441
0.697GlnTrp: 0.697 ± 0.215
1.161GlnTyr: 1.161 ± 0.342
0.0GlnXaa: 0.0 ± 0.0
Arg
5.186ArgAla: 5.186 ± 0.674
1.161ArgCys: 1.161 ± 0.375
4.257ArgAsp: 4.257 ± 0.637
4.412ArgGlu: 4.412 ± 0.546
3.638ArgPhe: 3.638 ± 0.425
4.722ArgGly: 4.722 ± 0.668
2.4ArgHis: 2.4 ± 0.364
2.167ArgIle: 2.167 ± 0.43
2.787ArgLys: 2.787 ± 0.393
7.044ArgLeu: 7.044 ± 0.872
2.245ArgMet: 2.245 ± 0.346
3.019ArgAsn: 3.019 ± 0.652
4.722ArgPro: 4.722 ± 0.74
3.096ArgGln: 3.096 ± 0.476
9.134ArgArg: 9.134 ± 1.687
5.496ArgSer: 5.496 ± 0.746
3.019ArgThr: 3.019 ± 0.41
4.722ArgVal: 4.722 ± 0.661
0.929ArgTrp: 0.929 ± 0.21
2.554ArgTyr: 2.554 ± 0.51
0.0ArgXaa: 0.0 ± 0.0
Ser
5.728SerAla: 5.728 ± 0.712
1.703SerCys: 1.703 ± 0.366
4.49SerAsp: 4.49 ± 0.713
4.567SerGlu: 4.567 ± 0.658
3.251SerPhe: 3.251 ± 0.408
5.573SerGly: 5.573 ± 0.898
1.084SerHis: 1.084 ± 0.281
2.632SerIle: 2.632 ± 0.428
1.935SerLys: 1.935 ± 0.476
5.883SerLeu: 5.883 ± 0.637
1.471SerMet: 1.471 ± 0.415
1.78SerAsn: 1.78 ± 0.294
4.567SerPro: 4.567 ± 0.664
2.09SerGln: 2.09 ± 0.511
6.038SerArg: 6.038 ± 0.785
5.651SerSer: 5.651 ± 0.872
4.567SerThr: 4.567 ± 0.729
3.561SerVal: 3.561 ± 0.534
1.316SerTrp: 1.316 ± 0.366
1.78SerTyr: 1.78 ± 0.283
0.0SerXaa: 0.0 ± 0.0
Thr
5.651ThrAla: 5.651 ± 0.662
1.78ThrCys: 1.78 ± 0.381
3.019ThrAsp: 3.019 ± 0.455
3.715ThrGlu: 3.715 ± 0.436
1.935ThrPhe: 1.935 ± 0.279
4.49ThrGly: 4.49 ± 0.674
1.084ThrHis: 1.084 ± 0.259
2.09ThrIle: 2.09 ± 0.357
1.471ThrLys: 1.471 ± 0.334
6.192ThrLeu: 6.192 ± 0.965
1.084ThrMet: 1.084 ± 0.207
2.013ThrAsn: 2.013 ± 0.514
3.948ThrPro: 3.948 ± 0.681
1.626ThrGln: 1.626 ± 0.404
3.251ThrArg: 3.251 ± 0.489
3.328ThrSer: 3.328 ± 0.524
3.406ThrThr: 3.406 ± 0.643
5.186ThrVal: 5.186 ± 0.712
0.464ThrTrp: 0.464 ± 0.223
2.864ThrTyr: 2.864 ± 0.558
0.0ThrXaa: 0.0 ± 0.0
Val
5.031ValAla: 5.031 ± 0.652
1.393ValCys: 1.393 ± 0.35
3.715ValAsp: 3.715 ± 0.593
3.019ValGlu: 3.019 ± 0.504
3.251ValPhe: 3.251 ± 0.396
3.715ValGly: 3.715 ± 0.448
0.929ValHis: 0.929 ± 0.278
2.941ValIle: 2.941 ± 0.52
2.09ValLys: 2.09 ± 0.356
6.889ValLeu: 6.889 ± 0.861
1.78ValMet: 1.78 ± 0.358
2.709ValAsn: 2.709 ± 0.574
5.186ValPro: 5.186 ± 0.679
2.787ValGln: 2.787 ± 0.58
4.877ValArg: 4.877 ± 0.544
5.264ValSer: 5.264 ± 0.655
3.638ValThr: 3.638 ± 0.586
4.257ValVal: 4.257 ± 0.66
0.619ValTrp: 0.619 ± 0.174
2.013ValTyr: 2.013 ± 0.282
0.0ValXaa: 0.0 ± 0.0
Trp
0.851TrpAla: 0.851 ± 0.298
0.464TrpCys: 0.464 ± 0.185
0.851TrpAsp: 0.851 ± 0.205
0.851TrpGlu: 0.851 ± 0.204
0.464TrpPhe: 0.464 ± 0.193
0.697TrpGly: 0.697 ± 0.217
0.232TrpHis: 0.232 ± 0.118
0.774TrpIle: 0.774 ± 0.236
0.542TrpLys: 0.542 ± 0.244
1.238TrpLeu: 1.238 ± 0.269
0.077TrpMet: 0.077 ± 0.11
0.774TrpAsn: 0.774 ± 0.246
0.387TrpPro: 0.387 ± 0.326
0.542TrpGln: 0.542 ± 0.187
1.238TrpArg: 1.238 ± 0.282
1.006TrpSer: 1.006 ± 0.262
1.006TrpThr: 1.006 ± 0.249
0.774TrpVal: 0.774 ± 0.217
0.077TrpTrp: 0.077 ± 0.076
0.774TrpTyr: 0.774 ± 0.214
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.4TyrAla: 2.4 ± 0.341
1.238TyrCys: 1.238 ± 0.296
2.787TyrAsp: 2.787 ± 0.574
1.316TyrGlu: 1.316 ± 0.405
2.013TyrPhe: 2.013 ± 0.452
2.322TyrGly: 2.322 ± 0.414
1.161TyrHis: 1.161 ± 0.215
1.084TyrIle: 1.084 ± 0.231
1.393TyrLys: 1.393 ± 0.351
3.328TyrLeu: 3.328 ± 0.671
1.548TyrMet: 1.548 ± 0.418
1.238TyrAsn: 1.238 ± 0.255
2.709TyrPro: 2.709 ± 0.362
1.548TyrGln: 1.548 ± 0.372
3.019TyrArg: 3.019 ± 0.471
2.09TyrSer: 2.09 ± 0.514
1.703TyrThr: 1.703 ± 0.452
3.174TyrVal: 3.174 ± 0.515
0.774TyrTrp: 0.774 ± 0.301
1.238TyrTyr: 1.238 ± 0.24
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 37 proteins (12920 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski