Amino acid dipepetide frequency for Pseudodesulfovibrio aespoeensis (strain ATCC 700646 / DSM 10631 / Aspo-2) (Desulfovibrio aespoeensis)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.453AlaAla: 11.453 ± 0.14	1.464AlaCys: 1.464 ± 0.048	5.938AlaAsp: 5.938 ± 0.082	6.29AlaGlu: 6.29 ± 0.087	3.749AlaPhe: 3.749 ± 0.063	9.141AlaGly: 9.141 ± 0.115	1.991AlaHis: 1.991 ± 0.049	4.851AlaIle: 4.851 ± 0.075	3.856AlaLys: 3.856 ± 0.067	11.309AlaLeu: 11.309 ± 0.124	3.567AlaMet: 3.567 ± 0.062	2.445AlaAsn: 2.445 ± 0.044	4.02AlaPro: 4.02 ± 0.072	3.431AlaGln: 3.431 ± 0.054	7.507AlaArg: 7.507 ± 0.098	5.358AlaSer: 5.358 ± 0.091	4.863AlaThr: 4.863 ± 0.082	8.044AlaVal: 8.044 ± 0.102	1.262AlaTrp: 1.262 ± 0.038	2.441AlaTyr: 2.441 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	1.368CysAla: 1.368 ± 0.037	0.227CysCys: 0.227 ± 0.018	0.675CysAsp: 0.675 ± 0.027	0.666CysGlu: 0.666 ± 0.026	0.467CysPhe: 0.467 ± 0.021	1.36CysGly: 1.36 ± 0.043	0.413CysHis: 0.413 ± 0.032	0.593CysIle: 0.593 ± 0.026	0.428CysLys: 0.428 ± 0.021	1.41CysLeu: 1.41 ± 0.044	0.295CysMet: 0.295 ± 0.017	0.381CysAsn: 0.381 ± 0.022	0.852CysPro: 0.852 ± 0.031	0.339CysGln: 0.339 ± 0.019	0.947CysArg: 0.947 ± 0.033	0.714CysSer: 0.714 ± 0.027	0.572CysThr: 0.572 ± 0.025	0.957CysVal: 0.957 ± 0.032	0.148CysTrp: 0.148 ± 0.011	0.325CysTyr: 0.325 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	5.659AspAla: 5.659 ± 0.081	0.699AspCys: 0.699 ± 0.029	3.156AspAsp: 3.156 ± 0.061	3.811AspGlu: 3.811 ± 0.06	2.527AspPhe: 2.527 ± 0.045	4.628AspGly: 4.628 ± 0.084	1.271AspHis: 1.271 ± 0.035	3.741AspIle: 3.741 ± 0.066	2.417AspLys: 2.417 ± 0.053	5.761AspLeu: 5.761 ± 0.076	1.888AspMet: 1.888 ± 0.042	1.632AspAsn: 1.632 ± 0.043	3.191AspPro: 3.191 ± 0.058	1.842AspGln: 1.842 ± 0.046	3.906AspArg: 3.906 ± 0.064	2.8AspSer: 2.8 ± 0.055	3.233AspThr: 3.233 ± 0.073	3.767AspVal: 3.767 ± 0.067	0.743AspTrp: 0.743 ± 0.024	1.696AspTyr: 1.696 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	6.797GluAla: 6.797 ± 0.095	0.658GluCys: 0.658 ± 0.028	3.024GluAsp: 3.024 ± 0.059	3.71GluGlu: 3.71 ± 0.079	2.351GluPhe: 2.351 ± 0.049	4.101GluGly: 4.101 ± 0.066	1.34GluHis: 1.34 ± 0.038	3.681GluIle: 3.681 ± 0.069	2.906GluLys: 2.906 ± 0.062	6.302GluLeu: 6.302 ± 0.076	1.855GluMet: 1.855 ± 0.042	1.992GluAsn: 1.992 ± 0.044	2.586GluPro: 2.586 ± 0.051	2.254GluGln: 2.254 ± 0.049	4.488GluArg: 4.488 ± 0.071	3.24GluSer: 3.24 ± 0.061	3.407GluThr: 3.407 ± 0.057	4.399GluVal: 4.399 ± 0.075	0.592GluTrp: 0.592 ± 0.024	1.585GluTyr: 1.585 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	3.793PheAla: 3.793 ± 0.063	0.572PheCys: 0.572 ± 0.025	2.593PheAsp: 2.593 ± 0.051	2.381PheGlu: 2.381 ± 0.049	1.841PhePhe: 1.841 ± 0.051	3.359PheGly: 3.359 ± 0.063	0.848PheHis: 0.848 ± 0.025	2.215PheIle: 2.215 ± 0.051	1.538PheLys: 1.538 ± 0.04	4.053PheLeu: 4.053 ± 0.066	1.149PheMet: 1.149 ± 0.036	1.298PheAsn: 1.298 ± 0.034	1.7PhePro: 1.7 ± 0.039	1.031PheGln: 1.031 ± 0.035	2.258PheArg: 2.258 ± 0.053	2.607PheSer: 2.607 ± 0.048	2.217PheThr: 2.217 ± 0.049	2.877PheVal: 2.877 ± 0.054	0.55PheTrp: 0.55 ± 0.023	1.095PheTyr: 1.095 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	7.255GlyAla: 7.255 ± 0.109	1.321GlyCys: 1.321 ± 0.043	4.397GlyAsp: 4.397 ± 0.074	4.995GlyGlu: 4.995 ± 0.068	3.616GlyPhe: 3.616 ± 0.07	6.634GlyGly: 6.634 ± 0.121	1.859GlyHis: 1.859 ± 0.044	4.381GlyIle: 4.381 ± 0.062	3.742GlyLys: 3.742 ± 0.059	9.262GlyLeu: 9.262 ± 0.106	2.757GlyMet: 2.757 ± 0.053	2.335GlyAsn: 2.335 ± 0.057	3.142GlyPro: 3.142 ± 0.064	3.124GlyGln: 3.124 ± 0.057	5.654GlyArg: 5.654 ± 0.085	4.534GlySer: 4.534 ± 0.084	4.335GlyThr: 4.335 ± 0.086	6.603GlyVal: 6.603 ± 0.085	1.086GlyTrp: 1.086 ± 0.037	2.426GlyTyr: 2.426 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	1.971HisAla: 1.971 ± 0.048	0.329HisCys: 0.329 ± 0.018	1.3HisAsp: 1.3 ± 0.035	1.255HisGlu: 1.255 ± 0.035	0.939HisPhe: 0.939 ± 0.03	1.904HisGly: 1.904 ± 0.042	0.567HisHis: 0.567 ± 0.026	1.042HisIle: 1.042 ± 0.031	0.749HisLys: 0.749 ± 0.03	2.168HisLeu: 2.168 ± 0.05	0.51HisMet: 0.51 ± 0.02	0.605HisAsn: 0.605 ± 0.023	1.392HisPro: 1.392 ± 0.035	0.641HisGln: 0.641 ± 0.026	1.249HisArg: 1.249 ± 0.036	1.053HisSer: 1.053 ± 0.029	1.062HisThr: 1.062 ± 0.034	1.443HisVal: 1.443 ± 0.037	0.263HisTrp: 0.263 ± 0.018	0.613HisTyr: 0.613 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	4.914IleAla: 4.914 ± 0.067	0.685IleCys: 0.685 ± 0.027	3.05IleAsp: 3.05 ± 0.055	3.373IleGlu: 3.373 ± 0.062	1.96IlePhe: 1.96 ± 0.041	4.128IleGly: 4.128 ± 0.067	1.081IleHis: 1.081 ± 0.026	2.931IleIle: 2.931 ± 0.064	2.255IleLys: 2.255 ± 0.054	5.395IleLeu: 5.395 ± 0.08	1.512IleMet: 1.512 ± 0.042	1.873IleAsn: 1.873 ± 0.046	2.725IlePro: 2.725 ± 0.052	1.48IleGln: 1.48 ± 0.041	3.676IleArg: 3.676 ± 0.059	3.056IleSer: 3.056 ± 0.057	3.008IleThr: 3.008 ± 0.07	3.643IleVal: 3.643 ± 0.066	0.518IleTrp: 0.518 ± 0.022	1.241IleTyr: 1.241 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	4.432LysAla: 4.432 ± 0.072	0.424LysCys: 0.424 ± 0.021	2.359LysAsp: 2.359 ± 0.052	2.494LysGlu: 2.494 ± 0.055	1.238LysPhe: 1.238 ± 0.041	3.317LysGly: 3.317 ± 0.068	0.792LysHis: 0.792 ± 0.033	2.16LysIle: 2.16 ± 0.052	2.265LysLys: 2.265 ± 0.072	3.648LysLeu: 3.648 ± 0.067	1.045LysMet: 1.045 ± 0.031	1.324LysAsn: 1.324 ± 0.036	2.08LysPro: 2.08 ± 0.045	1.291LysGln: 1.291 ± 0.038	2.71LysArg: 2.71 ± 0.059	2.157LysSer: 2.157 ± 0.046	2.48LysThr: 2.48 ± 0.056	2.857LysVal: 2.857 ± 0.059	0.417LysTrp: 0.417 ± 0.02	1.119LysTyr: 1.119 ± 0.036	0.0LysXaa: 0.0 ± 0.0
Leu	12.629LeuAla: 12.629 ± 0.142	1.433LeuCys: 1.433 ± 0.035	6.857LeuAsp: 6.857 ± 0.08	6.128LeuGlu: 6.128 ± 0.086	4.236LeuPhe: 4.236 ± 0.078	8.897LeuGly: 8.897 ± 0.099	2.066LeuHis: 2.066 ± 0.047	4.755LeuIle: 4.755 ± 0.073	4.419LeuLys: 4.419 ± 0.063	10.25LeuLeu: 10.25 ± 0.113	2.642LeuMet: 2.642 ± 0.051	2.902LeuAsn: 2.902 ± 0.051	5.221LeuPro: 5.221 ± 0.075	2.412LeuGln: 2.412 ± 0.048	6.459LeuArg: 6.459 ± 0.098	6.103LeuSer: 6.103 ± 0.081	5.896LeuThr: 5.896 ± 0.086	7.553LeuVal: 7.553 ± 0.089	1.105LeuTrp: 1.105 ± 0.037	2.332LeuTyr: 2.332 ± 0.048	0.0LeuXaa: 0.0 ± 0.0
Met	3.525MetAla: 3.525 ± 0.057	0.271MetCys: 0.271 ± 0.018	1.972MetAsp: 1.972 ± 0.045	1.785MetGlu: 1.785 ± 0.041	0.854MetPhe: 0.854 ± 0.028	2.31MetGly: 2.31 ± 0.045	0.603MetHis: 0.603 ± 0.024	1.353MetIle: 1.353 ± 0.037	1.321MetLys: 1.321 ± 0.037	2.829MetLeu: 2.829 ± 0.05	0.563MetMet: 0.563 ± 0.022	0.927MetAsn: 0.927 ± 0.029	1.521MetPro: 1.521 ± 0.044	0.922MetGln: 0.922 ± 0.031	1.822MetArg: 1.822 ± 0.042	1.659MetSer: 1.659 ± 0.038	1.897MetThr: 1.897 ± 0.045	2.132MetVal: 2.132 ± 0.047	0.188MetTrp: 0.188 ± 0.013	0.477MetTyr: 0.477 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	2.861AsnAla: 2.861 ± 0.057	0.422AsnCys: 0.422 ± 0.022	1.496AsnAsp: 1.496 ± 0.053	1.551AsnGlu: 1.551 ± 0.043	1.143AsnPhe: 1.143 ± 0.032	2.252AsnGly: 2.252 ± 0.058	0.616AsnHis: 0.616 ± 0.024	1.745AsnIle: 1.745 ± 0.046	1.075AsnLys: 1.075 ± 0.038	3.053AsnLeu: 3.053 ± 0.051	0.852AsnMet: 0.852 ± 0.03	0.868AsnAsn: 0.868 ± 0.031	1.915AsnPro: 1.915 ± 0.043	0.907AsnGln: 0.907 ± 0.029	1.824AsnArg: 1.824 ± 0.044	1.446AsnSer: 1.446 ± 0.044	1.582AsnThr: 1.582 ± 0.041	2.102AsnVal: 2.102 ± 0.042	0.379AsnTrp: 0.379 ± 0.019	0.79AsnTyr: 0.79 ± 0.031	0.0AsnXaa: 0.0 ± 0.0
Pro	4.855ProAla: 4.855 ± 0.076	0.576ProCys: 0.576 ± 0.025	3.716ProAsp: 3.716 ± 0.064	3.736ProGlu: 3.736 ± 0.06	1.939ProPhe: 1.939 ± 0.051	4.779ProGly: 4.779 ± 0.076	0.98ProHis: 0.98 ± 0.032	1.917ProIle: 1.917 ± 0.046	1.705ProLys: 1.705 ± 0.038	4.667ProLeu: 4.667 ± 0.075	1.273ProMet: 1.273 ± 0.035	1.164ProAsn: 1.164 ± 0.032	2.035ProPro: 2.035 ± 0.063	1.447ProGln: 1.447 ± 0.037	2.508ProArg: 2.508 ± 0.053	2.3ProSer: 2.3 ± 0.047	2.113ProThr: 2.113 ± 0.047	4.212ProVal: 4.212 ± 0.065	0.648ProTrp: 0.648 ± 0.027	1.215ProTyr: 1.215 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	3.929GlnAla: 3.929 ± 0.059	0.413GlnCys: 0.413 ± 0.02	1.619GlnAsp: 1.619 ± 0.042	1.98GlnGlu: 1.98 ± 0.047	1.083GlnPhe: 1.083 ± 0.031	2.912GlnGly: 2.912 ± 0.056	0.568GlnHis: 0.568 ± 0.023	1.55GlnIle: 1.55 ± 0.041	1.245GlnLys: 1.245 ± 0.039	2.742GlnLeu: 2.742 ± 0.057	0.905GlnMet: 0.905 ± 0.029	0.865GlnAsn: 0.865 ± 0.032	1.379GlnPro: 1.379 ± 0.033	1.064GlnGln: 1.064 ± 0.038	1.975GlnArg: 1.975 ± 0.046	1.754GlnSer: 1.754 ± 0.043	1.772GlnThr: 1.772 ± 0.046	2.271GlnVal: 2.271 ± 0.047	0.431GlnTrp: 0.431 ± 0.02	0.785GlnTyr: 0.785 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	6.166ArgAla: 6.166 ± 0.087	0.759ArgCys: 0.759 ± 0.03	3.884ArgAsp: 3.884 ± 0.071	4.784ArgGlu: 4.784 ± 0.077	2.901ArgPhe: 2.901 ± 0.057	4.181ArgGly: 4.181 ± 0.066	1.65ArgHis: 1.65 ± 0.043	3.947ArgIle: 3.947 ± 0.063	2.939ArgLys: 2.939 ± 0.059	7.365ArgLeu: 7.365 ± 0.089	1.998ArgMet: 1.998 ± 0.038	1.864ArgAsn: 1.864 ± 0.045	2.972ArgPro: 2.972 ± 0.059	2.579ArgGln: 2.579 ± 0.057	4.388ArgArg: 4.388 ± 0.081	3.302ArgSer: 3.302 ± 0.054	3.478ArgThr: 3.478 ± 0.055	4.453ArgVal: 4.453 ± 0.07	0.701ArgTrp: 0.701 ± 0.029	1.742ArgTyr: 1.742 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	4.89SerAla: 4.89 ± 0.081	0.625SerCys: 0.625 ± 0.025	2.806SerAsp: 2.806 ± 0.061	2.987SerGlu: 2.987 ± 0.058	2.223SerPhe: 2.223 ± 0.049	5.664SerGly: 5.664 ± 0.085	1.156SerHis: 1.156 ± 0.032	2.939SerIle: 2.939 ± 0.057	1.933SerLys: 1.933 ± 0.044	6.135SerLeu: 6.135 ± 0.093	1.702SerMet: 1.702 ± 0.035	1.388SerAsn: 1.388 ± 0.04	2.593SerPro: 2.593 ± 0.054	1.717SerGln: 1.717 ± 0.04	3.657SerArg: 3.657 ± 0.063	3.001SerSer: 3.001 ± 0.066	2.647SerThr: 2.647 ± 0.064	4.09SerVal: 4.09 ± 0.068	0.688SerTrp: 0.688 ± 0.025	1.349SerTyr: 1.349 ± 0.042	0.0SerXaa: 0.0 ± 0.0
Thr	5.185ThrAla: 5.185 ± 0.077	0.644ThrCys: 0.644 ± 0.028	2.986ThrAsp: 2.986 ± 0.053	2.575ThrGlu: 2.575 ± 0.056	2.073ThrPhe: 2.073 ± 0.049	5.395ThrGly: 5.395 ± 0.063	1.069ThrHis: 1.069 ± 0.03	2.919ThrIle: 2.919 ± 0.057	1.676ThrLys: 1.676 ± 0.044	6.321ThrLeu: 6.321 ± 0.095	1.424ThrMet: 1.424 ± 0.036	1.415ThrAsn: 1.415 ± 0.043	3.305ThrPro: 3.305 ± 0.06	1.386ThrGln: 1.386 ± 0.038	3.276ThrArg: 3.276 ± 0.06	2.681ThrSer: 2.681 ± 0.061	2.893ThrThr: 2.893 ± 0.065	4.508ThrVal: 4.508 ± 0.094	0.619ThrTrp: 0.619 ± 0.023	1.358ThrTyr: 1.358 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	7.813ValAla: 7.813 ± 0.111	1.067ValCys: 1.067 ± 0.038	4.297ValAsp: 4.297 ± 0.063	4.669ValGlu: 4.669 ± 0.068	3.19ValPhe: 3.19 ± 0.056	5.474ValGly: 5.474 ± 0.081	1.405ValHis: 1.405 ± 0.036	4.118ValIle: 4.118 ± 0.064	2.649ValLys: 2.649 ± 0.061	7.586ValLeu: 7.586 ± 0.093	2.023ValMet: 2.023 ± 0.046	2.406ValAsn: 2.406 ± 0.054	3.268ValPro: 3.268 ± 0.057	2.1ValGln: 2.1 ± 0.052	5.191ValArg: 5.191 ± 0.069	4.38ValSer: 4.38 ± 0.06	4.227ValThr: 4.227 ± 0.079	5.952ValVal: 5.952 ± 0.098	0.793ValTrp: 0.793 ± 0.028	1.778ValTyr: 1.778 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	1.053TrpAla: 1.053 ± 0.037	0.133TrpCys: 0.133 ± 0.01	0.67TrpAsp: 0.67 ± 0.026	0.673TrpGlu: 0.673 ± 0.025	0.476TrpPhe: 0.476 ± 0.022	0.893TrpGly: 0.893 ± 0.029	0.252TrpHis: 0.252 ± 0.017	0.548TrpIle: 0.548 ± 0.022	0.497TrpLys: 0.497 ± 0.019	1.334TrpLeu: 1.334 ± 0.039	0.329TrpMet: 0.329 ± 0.019	0.411TrpAsn: 0.411 ± 0.021	0.614TrpPro: 0.614 ± 0.027	0.467TrpGln: 0.467 ± 0.022	0.814TrpArg: 0.814 ± 0.025	0.6TrpSer: 0.6 ± 0.024	0.674TrpThr: 0.674 ± 0.027	0.758TrpVal: 0.758 ± 0.029	0.178TrpTrp: 0.178 ± 0.013	0.294TrpTyr: 0.294 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.433TyrAla: 2.433 ± 0.044	0.418TyrCys: 0.418 ± 0.02	1.572TyrAsp: 1.572 ± 0.042	1.421TyrGlu: 1.421 ± 0.037	1.171TyrPhe: 1.171 ± 0.037	2.131TyrGly: 2.131 ± 0.052	0.527TyrHis: 0.527 ± 0.023	1.12TyrIle: 1.12 ± 0.032	0.993TyrLys: 0.993 ± 0.034	2.706TyrLeu: 2.706 ± 0.05	0.639TyrMet: 0.639 ± 0.024	0.784TyrAsn: 0.784 ± 0.028	1.273TyrPro: 1.273 ± 0.039	0.807TyrGln: 0.807 ± 0.028	1.745TyrArg: 1.745 ± 0.039	1.446TyrSer: 1.446 ± 0.043	1.351TyrThr: 1.351 ± 0.039	1.766TyrVal: 1.766 ± 0.042	0.357TyrTrp: 0.357 ± 0.018	0.841TyrTyr: 0.841 ± 0.032	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3269 proteins (1066561 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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