Amino acid dipepetide frequency for Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815) (Burkholderia phymatum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.773AlaAla: 16.773 ± 0.138	1.439AlaCys: 1.439 ± 0.028	6.5AlaAsp: 6.5 ± 0.059	5.659AlaGlu: 5.659 ± 0.065	4.393AlaPhe: 4.393 ± 0.049	9.977AlaGly: 9.977 ± 0.084	2.939AlaHis: 2.939 ± 0.035	5.793AlaIle: 5.793 ± 0.063	3.796AlaLys: 3.796 ± 0.053	13.89AlaLeu: 13.89 ± 0.094	3.312AlaMet: 3.312 ± 0.035	3.452AlaAsn: 3.452 ± 0.063	5.635AlaPro: 5.635 ± 0.059	5.403AlaGln: 5.403 ± 0.057	8.955AlaArg: 8.955 ± 0.07	7.751AlaSer: 7.751 ± 0.075	6.419AlaThr: 6.419 ± 0.075	8.789AlaVal: 8.789 ± 0.072	1.681AlaTrp: 1.681 ± 0.029	2.689AlaTyr: 2.689 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	1.366CysAla: 1.366 ± 0.026	0.147CysCys: 0.147 ± 0.008	0.607CysAsp: 0.607 ± 0.017	0.541CysGlu: 0.541 ± 0.015	0.369CysPhe: 0.369 ± 0.012	1.05CysGly: 1.05 ± 0.024	0.28CysHis: 0.28 ± 0.011	0.453CysIle: 0.453 ± 0.016	0.247CysLys: 0.247 ± 0.01	0.827CysLeu: 0.827 ± 0.019	0.226CysMet: 0.226 ± 0.009	0.269CysAsn: 0.269 ± 0.01	0.476CysPro: 0.476 ± 0.016	0.227CysGln: 0.227 ± 0.01	0.647CysArg: 0.647 ± 0.016	0.571CysSer: 0.571 ± 0.018	0.54CysThr: 0.54 ± 0.016	0.873CysVal: 0.873 ± 0.018	0.126CysTrp: 0.126 ± 0.006	0.248CysTyr: 0.248 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.831AspAla: 7.831 ± 0.071	0.487AspCys: 0.487 ± 0.014	3.277AspAsp: 3.277 ± 0.042	3.541AspGlu: 3.541 ± 0.042	1.929AspPhe: 1.929 ± 0.027	4.623AspGly: 4.623 ± 0.045	1.173AspHis: 1.173 ± 0.023	2.668AspIle: 2.668 ± 0.041	1.579AspLys: 1.579 ± 0.028	5.143AspLeu: 5.143 ± 0.057	1.267AspMet: 1.267 ± 0.022	1.421AspAsn: 1.421 ± 0.023	2.834AspPro: 2.834 ± 0.036	1.531AspGln: 1.531 ± 0.026	3.43AspArg: 3.43 ± 0.036	2.624AspSer: 2.624 ± 0.034	2.91AspThr: 2.91 ± 0.038	4.515AspVal: 4.515 ± 0.046	0.887AspTrp: 0.887 ± 0.022	1.523AspTyr: 1.523 ± 0.027	0.0AspXaa: 0.0 ± 0.0
Glu	6.312GluAla: 6.312 ± 0.07	0.447GluCys: 0.447 ± 0.016	2.118GluAsp: 2.118 ± 0.033	2.406GluGlu: 2.406 ± 0.039	1.73GluPhe: 1.73 ± 0.028	3.419GluGly: 3.419 ± 0.047	1.492GluHis: 1.492 ± 0.027	2.666GluIle: 2.666 ± 0.035	1.774GluLys: 1.774 ± 0.03	5.414GluLeu: 5.414 ± 0.063	1.244GluMet: 1.244 ± 0.025	1.355GluAsn: 1.355 ± 0.028	2.501GluPro: 2.501 ± 0.035	2.384GluGln: 2.384 ± 0.035	4.956GluArg: 4.956 ± 0.061	2.69GluSer: 2.69 ± 0.031	2.793GluThr: 2.793 ± 0.041	3.46GluVal: 3.46 ± 0.045	0.74GluTrp: 0.74 ± 0.018	1.149GluTyr: 1.149 ± 0.022	0.0GluXaa: 0.0 ± 0.0
Phe	4.736PheAla: 4.736 ± 0.049	0.44PheCys: 0.44 ± 0.013	2.733PheAsp: 2.733 ± 0.034	2.081PheGlu: 2.081 ± 0.032	1.43PhePhe: 1.43 ± 0.035	3.604PheGly: 3.604 ± 0.046	0.764PheHis: 0.764 ± 0.022	1.668PheIle: 1.668 ± 0.031	0.987PheLys: 0.987 ± 0.02	2.909PheLeu: 2.909 ± 0.044	0.83PheMet: 0.83 ± 0.019	1.153PheAsn: 1.153 ± 0.024	1.559PhePro: 1.559 ± 0.027	0.976PheGln: 0.976 ± 0.019	2.122PheArg: 2.122 ± 0.031	2.278PheSer: 2.278 ± 0.035	1.939PheThr: 1.939 ± 0.032	3.18PheVal: 3.18 ± 0.043	0.507PheTrp: 0.507 ± 0.016	0.965PheTyr: 0.965 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	9.271GlyAla: 9.271 ± 0.09	0.918GlyCys: 0.918 ± 0.019	3.962GlyAsp: 3.962 ± 0.045	4.17GlyGlu: 4.17 ± 0.043	3.403GlyPhe: 3.403 ± 0.038	6.561GlyGly: 6.561 ± 0.094	1.966GlyHis: 1.966 ± 0.03	4.29GlyIle: 4.29 ± 0.051	3.27GlyLys: 3.27 ± 0.044	7.591GlyLeu: 7.591 ± 0.065	2.221GlyMet: 2.221 ± 0.033	2.408GlyAsn: 2.408 ± 0.044	2.863GlyPro: 2.863 ± 0.042	2.677GlyGln: 2.677 ± 0.035	5.131GlyArg: 5.131 ± 0.052	4.729GlySer: 4.729 ± 0.057	4.636GlyThr: 4.636 ± 0.069	6.613GlyVal: 6.613 ± 0.054	1.325GlyTrp: 1.325 ± 0.025	2.391GlyTyr: 2.391 ± 0.036	0.0GlyXaa: 0.0 ± 0.0
His	3.228HisAla: 3.228 ± 0.042	0.291HisCys: 0.291 ± 0.012	1.456HisAsp: 1.456 ± 0.026	1.29HisGlu: 1.29 ± 0.024	0.967HisPhe: 0.967 ± 0.021	2.151HisGly: 2.151 ± 0.032	0.69HisHis: 0.69 ± 0.019	1.014HisIle: 1.014 ± 0.022	0.548HisLys: 0.548 ± 0.015	2.206HisLeu: 2.206 ± 0.028	0.572HisMet: 0.572 ± 0.016	0.548HisAsn: 0.548 ± 0.014	1.439HisPro: 1.439 ± 0.023	0.674HisGln: 0.674 ± 0.017	1.648HisArg: 1.648 ± 0.026	1.168HisSer: 1.168 ± 0.02	1.163HisThr: 1.163 ± 0.02	1.871HisVal: 1.871 ± 0.03	0.392HisTrp: 0.392 ± 0.013	0.663HisTyr: 0.663 ± 0.015	0.0HisXaa: 0.0 ± 0.0
Ile	7.184IleAla: 7.184 ± 0.06	0.478IleCys: 0.478 ± 0.014	3.64IleAsp: 3.64 ± 0.044	3.292IleGlu: 3.292 ± 0.047	1.475IlePhe: 1.475 ± 0.027	4.773IleGly: 4.773 ± 0.045	0.954IleHis: 0.954 ± 0.02	1.621IleIle: 1.621 ± 0.029	1.35IleLys: 1.35 ± 0.03	3.307IleLeu: 3.307 ± 0.048	0.798IleMet: 0.798 ± 0.022	1.411IleAsn: 1.411 ± 0.028	2.086IlePro: 2.086 ± 0.033	1.204IleGln: 1.204 ± 0.023	2.883IleArg: 2.883 ± 0.04	2.5IleSer: 2.5 ± 0.031	2.442IleThr: 2.442 ± 0.035	4.525IleVal: 4.525 ± 0.045	0.536IleTrp: 0.536 ± 0.015	1.05IleTyr: 1.05 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	3.628LysAla: 3.628 ± 0.047	0.19LysCys: 0.19 ± 0.01	1.539LysAsp: 1.539 ± 0.03	1.492LysGlu: 1.492 ± 0.027	0.864LysPhe: 0.864 ± 0.02	2.247LysGly: 2.247 ± 0.035	0.73LysHis: 0.73 ± 0.018	1.566LysIle: 1.566 ± 0.03	1.31LysLys: 1.31 ± 0.032	3.409LysLeu: 3.409 ± 0.037	0.786LysMet: 0.786 ± 0.019	0.899LysAsn: 0.899 ± 0.024	2.003LysPro: 2.003 ± 0.029	1.283LysGln: 1.283 ± 0.025	2.504LysArg: 2.504 ± 0.037	1.786LysSer: 1.786 ± 0.031	1.916LysThr: 1.916 ± 0.031	2.288LysVal: 2.288 ± 0.036	0.407LysTrp: 0.407 ± 0.013	0.709LysTyr: 0.709 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	13.279LeuAla: 13.279 ± 0.096	1.087LeuCys: 1.087 ± 0.02	5.922LeuAsp: 5.922 ± 0.053	4.91LeuGlu: 4.91 ± 0.057	3.633LeuPhe: 3.633 ± 0.05	7.77LeuGly: 7.77 ± 0.065	2.35LeuHis: 2.35 ± 0.033	4.688LeuIle: 4.688 ± 0.051	3.327LeuLys: 3.327 ± 0.039	9.842LeuLeu: 9.842 ± 0.088	2.285LeuMet: 2.285 ± 0.032	2.805LeuAsn: 2.805 ± 0.043	5.563LeuPro: 5.563 ± 0.051	3.294LeuGln: 3.294 ± 0.043	7.086LeuArg: 7.086 ± 0.067	6.269LeuSer: 6.269 ± 0.058	5.704LeuThr: 5.704 ± 0.058	7.208LeuVal: 7.208 ± 0.063	1.085LeuTrp: 1.085 ± 0.025	2.177LeuTyr: 2.177 ± 0.033	0.0LeuXaa: 0.0 ± 0.0
Met	2.416MetAla: 2.416 ± 0.031	0.205MetCys: 0.205 ± 0.01	0.956MetAsp: 0.956 ± 0.022	0.946MetGlu: 0.946 ± 0.019	0.781MetPhe: 0.781 ± 0.018	1.562MetGly: 1.562 ± 0.027	0.639MetHis: 0.639 ± 0.017	1.157MetIle: 1.157 ± 0.023	1.089MetLys: 1.089 ± 0.022	2.723MetLeu: 2.723 ± 0.037	0.639MetMet: 0.639 ± 0.017	0.967MetAsn: 0.967 ± 0.021	1.501MetPro: 1.501 ± 0.027	1.089MetGln: 1.089 ± 0.021	1.922MetArg: 1.922 ± 0.028	1.884MetSer: 1.884 ± 0.029	1.676MetThr: 1.676 ± 0.026	1.437MetVal: 1.437 ± 0.023	0.233MetTrp: 0.233 ± 0.01	0.435MetTyr: 0.435 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	3.784AsnAla: 3.784 ± 0.055	0.285AsnCys: 0.285 ± 0.012	1.583AsnAsp: 1.583 ± 0.023	1.429AsnGlu: 1.429 ± 0.026	0.97AsnPhe: 0.97 ± 0.019	2.643AsnGly: 2.643 ± 0.042	0.551AsnHis: 0.551 ± 0.018	1.286AsnIle: 1.286 ± 0.038	0.691AsnLys: 0.691 ± 0.018	2.735AsnLeu: 2.735 ± 0.038	0.615AsnMet: 0.615 ± 0.018	0.874AsnAsn: 0.874 ± 0.045	1.773AsnPro: 1.773 ± 0.029	0.958AsnGln: 0.958 ± 0.025	1.926AsnArg: 1.926 ± 0.027	1.457AsnSer: 1.457 ± 0.05	1.584AsnThr: 1.584 ± 0.035	2.402AsnVal: 2.402 ± 0.058	0.444AsnTrp: 0.444 ± 0.013	0.711AsnTyr: 0.711 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	6.252ProAla: 6.252 ± 0.056	0.395ProCys: 0.395 ± 0.013	3.225ProAsp: 3.225 ± 0.044	2.852ProGlu: 2.852 ± 0.04	1.926ProPhe: 1.926 ± 0.029	4.024ProGly: 4.024 ± 0.045	1.286ProHis: 1.286 ± 0.024	1.992ProIle: 1.992 ± 0.029	1.451ProLys: 1.451 ± 0.022	4.977ProLeu: 4.977 ± 0.047	1.125ProMet: 1.125 ± 0.022	1.448ProAsn: 1.448 ± 0.025	2.355ProPro: 2.355 ± 0.038	1.855ProGln: 1.855 ± 0.027	2.898ProArg: 2.898 ± 0.037	2.942ProSer: 2.942 ± 0.037	2.59ProThr: 2.59 ± 0.034	4.286ProVal: 4.286 ± 0.047	0.666ProTrp: 0.666 ± 0.02	1.223ProTyr: 1.223 ± 0.023	0.0ProXaa: 0.0 ± 0.0
Gln	4.397GlnAla: 4.397 ± 0.049	0.295GlnCys: 0.295 ± 0.011	1.327GlnAsp: 1.327 ± 0.022	1.334GlnGlu: 1.334 ± 0.021	1.307GlnPhe: 1.307 ± 0.027	2.465GlnGly: 2.465 ± 0.039	0.997GlnHis: 0.997 ± 0.023	1.967GlnIle: 1.967 ± 0.028	1.159GlnLys: 1.159 ± 0.024	3.767GlnLeu: 3.767 ± 0.046	1.036GlnMet: 1.036 ± 0.02	0.976GlnAsn: 0.976 ± 0.023	2.033GlnPro: 2.033 ± 0.034	1.89GlnGln: 1.89 ± 0.035	3.026GlnArg: 3.026 ± 0.04	2.148GlnSer: 2.148 ± 0.032	2.064GlnThr: 2.064 ± 0.031	2.409GlnVal: 2.409 ± 0.034	0.547GlnTrp: 0.547 ± 0.016	0.908GlnTyr: 0.908 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	8.34ArgAla: 8.34 ± 0.075	0.684ArgCys: 0.684 ± 0.021	4.08ArgAsp: 4.08 ± 0.041	4.363ArgGlu: 4.363 ± 0.056	2.973ArgPhe: 2.973 ± 0.04	4.616ArgGly: 4.616 ± 0.042	1.959ArgHis: 1.959 ± 0.033	3.703ArgIle: 3.703 ± 0.037	2.25ArgLys: 2.25 ± 0.032	7.084ArgLeu: 7.084 ± 0.064	1.869ArgMet: 1.869 ± 0.027	2.004ArgAsn: 2.004 ± 0.03	3.01ArgPro: 3.01 ± 0.037	2.565ArgGln: 2.565 ± 0.038	5.476ArgArg: 5.476 ± 0.052	3.676ArgSer: 3.676 ± 0.045	3.534ArgThr: 3.534 ± 0.037	5.405ArgVal: 5.405 ± 0.054	1.057ArgTrp: 1.057 ± 0.028	1.998ArgTyr: 1.998 ± 0.029	0.0ArgXaa: 0.0 ± 0.0
Ser	6.886SerAla: 6.886 ± 0.075	0.494SerCys: 0.494 ± 0.015	3.03SerAsp: 3.03 ± 0.033	2.607SerGlu: 2.607 ± 0.032	2.202SerPhe: 2.202 ± 0.031	5.363SerGly: 5.363 ± 0.057	1.298SerHis: 1.298 ± 0.023	2.912SerIle: 2.912 ± 0.034	1.785SerLys: 1.785 ± 0.027	5.909SerLeu: 5.909 ± 0.052	1.516SerMet: 1.516 ± 0.027	1.804SerAsn: 1.804 ± 0.043	2.853SerPro: 2.853 ± 0.035	1.931SerGln: 1.931 ± 0.034	3.931SerArg: 3.931 ± 0.044	3.549SerSer: 3.549 ± 0.051	3.357SerThr: 3.357 ± 0.05	4.61SerVal: 4.61 ± 0.051	0.718SerTrp: 0.718 ± 0.019	1.373SerTyr: 1.373 ± 0.025	0.0SerXaa: 0.0 ± 0.0
Thr	6.089ThrAla: 6.089 ± 0.084	0.503ThrCys: 0.503 ± 0.016	2.741ThrAsp: 2.741 ± 0.036	2.295ThrGlu: 2.295 ± 0.035	2.061ThrPhe: 2.061 ± 0.028	4.912ThrGly: 4.912 ± 0.062	1.366ThrHis: 1.366 ± 0.022	2.617ThrIle: 2.617 ± 0.036	1.331ThrLys: 1.331 ± 0.024	6.454ThrLeu: 6.454 ± 0.066	1.243ThrMet: 1.243 ± 0.023	1.49ThrAsn: 1.49 ± 0.049	3.46ThrPro: 3.46 ± 0.038	2.011ThrGln: 2.011 ± 0.03	3.699ThrArg: 3.699 ± 0.037	3.154ThrSer: 3.154 ± 0.039	3.071ThrThr: 3.071 ± 0.057	4.457ThrVal: 4.457 ± 0.05	0.726ThrTrp: 0.726 ± 0.018	1.27ThrTyr: 1.27 ± 0.028	0.0ThrXaa: 0.0 ± 0.0
Val	9.519ValAla: 9.519 ± 0.085	0.879ValCys: 0.879 ± 0.019	4.45ValAsp: 4.45 ± 0.055	4.109ValGlu: 4.109 ± 0.047	2.863ValPhe: 2.863 ± 0.038	5.578ValGly: 5.578 ± 0.058	1.622ValHis: 1.622 ± 0.027	3.818ValIle: 3.818 ± 0.048	2.564ValLys: 2.564 ± 0.038	7.76ValLeu: 7.76 ± 0.071	1.828ValMet: 1.828 ± 0.032	2.287ValAsn: 2.287 ± 0.057	3.946ValPro: 3.946 ± 0.04	2.556ValGln: 2.556 ± 0.035	5.206ValArg: 5.206 ± 0.053	4.844ValSer: 4.844 ± 0.055	4.615ValThr: 4.615 ± 0.045	6.345ValVal: 6.345 ± 0.056	0.957ValTrp: 0.957 ± 0.02	1.731ValTyr: 1.731 ± 0.027	0.0ValXaa: 0.0 ± 0.0
Trp	1.143TrpAla: 1.143 ± 0.022	0.151TrpCys: 0.151 ± 0.009	0.636TrpAsp: 0.636 ± 0.017	0.496TrpGlu: 0.496 ± 0.017	0.55TrpPhe: 0.55 ± 0.015	0.856TrpGly: 0.856 ± 0.018	0.404TrpHis: 0.404 ± 0.014	0.744TrpIle: 0.744 ± 0.019	0.432TrpLys: 0.432 ± 0.017	1.89TrpLeu: 1.89 ± 0.036	0.384TrpMet: 0.384 ± 0.012	0.49TrpAsn: 0.49 ± 0.016	0.64TrpPro: 0.64 ± 0.015	0.655TrpGln: 0.655 ± 0.017	1.205TrpArg: 1.205 ± 0.024	0.826TrpSer: 0.826 ± 0.021	0.745TrpThr: 0.745 ± 0.018	0.893TrpVal: 0.893 ± 0.02	0.216TrpTrp: 0.216 ± 0.01	0.312TrpTyr: 0.312 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.814TyrAla: 2.814 ± 0.037	0.274TyrCys: 0.274 ± 0.011	1.409TyrAsp: 1.409 ± 0.023	1.236TyrGlu: 1.236 ± 0.025	1.037TyrPhe: 1.037 ± 0.021	2.202TyrGly: 2.202 ± 0.03	0.519TyrHis: 0.519 ± 0.015	0.889TyrIle: 0.889 ± 0.02	0.615TyrLys: 0.615 ± 0.019	2.447TyrLeu: 2.447 ± 0.034	0.463TyrMet: 0.463 ± 0.013	0.642TyrAsn: 0.642 ± 0.019	1.238TyrPro: 1.238 ± 0.025	0.888TyrGln: 0.888 ± 0.02	1.993TyrArg: 1.993 ± 0.029	1.281TyrSer: 1.281 ± 0.024	1.252TyrThr: 1.252 ± 0.023	1.913TyrVal: 1.913 ± 0.031	0.414TyrTrp: 0.414 ± 0.014	0.661TyrTyr: 0.661 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 7461 proteins (2416160 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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