Amino acid dipepetide frequency for Blochmannia floridanus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.881AlaAla: 2.881 ± 0.143
0.815AlaCys: 0.815 ± 0.069
1.784AlaAsp: 1.784 ± 0.107
1.794AlaGlu: 1.794 ± 0.111
1.83AlaPhe: 1.83 ± 0.119
2.871AlaGly: 2.871 ± 0.146
1.066AlaHis: 1.066 ± 0.072
5.086AlaIle: 5.086 ± 0.167
2.604AlaLys: 2.604 ± 0.14
5.419AlaLeu: 5.419 ± 0.199
1.353AlaMet: 1.353 ± 0.093
2.179AlaAsn: 2.179 ± 0.116
1.297AlaPro: 1.297 ± 0.075
2.056AlaGln: 2.056 ± 0.115
2.338AlaArg: 2.338 ± 0.129
2.814AlaSer: 2.814 ± 0.143
2.204AlaThr: 2.204 ± 0.137
2.789AlaVal: 2.789 ± 0.152
0.472AlaTrp: 0.472 ± 0.048
2.004AlaTyr: 2.004 ± 0.092
0.0AlaXaa: 0.0 ± 0.0
Cys
0.646CysAla: 0.646 ± 0.051
0.41CysCys: 0.41 ± 0.047
0.769CysAsp: 0.769 ± 0.067
0.554CysGlu: 0.554 ± 0.055
0.825CysPhe: 0.825 ± 0.065
1.03CysGly: 1.03 ± 0.07
0.441CysHis: 0.441 ± 0.049
1.856CysIle: 1.856 ± 0.095
0.928CysLys: 0.928 ± 0.069
1.307CysLeu: 1.307 ± 0.09
0.379CysMet: 0.379 ± 0.043
1.169CysAsn: 1.169 ± 0.078
0.492CysPro: 0.492 ± 0.059
0.502CysGln: 0.502 ± 0.05
0.6CysArg: 0.6 ± 0.052
1.133CysSer: 1.133 ± 0.071
0.882CysThr: 0.882 ± 0.062
1.066CysVal: 1.066 ± 0.083
0.236CysTrp: 0.236 ± 0.032
0.554CysTyr: 0.554 ± 0.047
0.0CysXaa: 0.0 ± 0.0
Asp
1.846AspAla: 1.846 ± 0.106
0.8AspCys: 0.8 ± 0.064
1.794AspAsp: 1.794 ± 0.103
1.856AspGlu: 1.856 ± 0.118
2.317AspPhe: 2.317 ± 0.119
2.353AspGly: 2.353 ± 0.121
1.138AspHis: 1.138 ± 0.083
5.619AspIle: 5.619 ± 0.196
2.717AspLys: 2.717 ± 0.123
4.85AspLeu: 4.85 ± 0.151
1.277AspMet: 1.277 ± 0.072
2.994AspAsn: 2.994 ± 0.129
1.605AspPro: 1.605 ± 0.09
1.969AspGln: 1.969 ± 0.111
2.04AspArg: 2.04 ± 0.117
2.922AspSer: 2.922 ± 0.126
2.24AspThr: 2.24 ± 0.102
3.014AspVal: 3.014 ± 0.139
0.518AspTrp: 0.518 ± 0.054
1.979AspTyr: 1.979 ± 0.106
0.0AspXaa: 0.0 ± 0.0
Glu
1.938GluAla: 1.938 ± 0.12
0.605GluCys: 0.605 ± 0.054
1.671GluAsp: 1.671 ± 0.097
2.445GluGlu: 2.445 ± 0.125
1.963GluPhe: 1.963 ± 0.096
1.989GluGly: 1.989 ± 0.11
0.979GluHis: 0.979 ± 0.073
5.265GluIle: 5.265 ± 0.17
3.522GluLys: 3.522 ± 0.145
4.968GluLeu: 4.968 ± 0.178
1.148GluMet: 1.148 ± 0.075
2.584GluAsn: 2.584 ± 0.118
1.107GluPro: 1.107 ± 0.078
1.769GluGln: 1.769 ± 0.109
2.21GluArg: 2.21 ± 0.125
3.327GluSer: 3.327 ± 0.144
1.764GluThr: 1.764 ± 0.115
2.563GluVal: 2.563 ± 0.117
0.487GluTrp: 0.487 ± 0.052
2.081GluTyr: 2.081 ± 0.096
0.0GluXaa: 0.0 ± 0.0
Phe
1.671PheAla: 1.671 ± 0.097
0.795PheCys: 0.795 ± 0.073
2.363PheAsp: 2.363 ± 0.121
1.64PheGlu: 1.64 ± 0.103
2.492PhePhe: 2.492 ± 0.157
2.83PheGly: 2.83 ± 0.123
1.082PheHis: 1.082 ± 0.073
4.875PheIle: 4.875 ± 0.22
2.671PheLys: 2.671 ± 0.125
4.665PheLeu: 4.665 ± 0.178
1.077PheMet: 1.077 ± 0.086
3.24PheAsn: 3.24 ± 0.112
1.692PhePro: 1.692 ± 0.102
1.487PheGln: 1.487 ± 0.084
1.599PheArg: 1.599 ± 0.088
3.814PheSer: 3.814 ± 0.142
1.866PheThr: 1.866 ± 0.103
2.256PheVal: 2.256 ± 0.116
0.502PheTrp: 0.502 ± 0.058
1.912PheTyr: 1.912 ± 0.112
0.0PheXaa: 0.0 ± 0.0
Gly
2.866GlyAla: 2.866 ± 0.127
1.036GlyCys: 1.036 ± 0.071
2.579GlyAsp: 2.579 ± 0.142
2.409GlyGlu: 2.409 ± 0.136
2.65GlyPhe: 2.65 ± 0.124
3.85GlyGly: 3.85 ± 0.164
1.405GlyHis: 1.405 ± 0.088
6.864GlyIle: 6.864 ± 0.212
3.865GlyLys: 3.865 ± 0.148
5.342GlyLeu: 5.342 ± 0.187
1.743GlyMet: 1.743 ± 0.096
2.702GlyAsn: 2.702 ± 0.131
1.482GlyPro: 1.482 ± 0.082
1.835GlyGln: 1.835 ± 0.106
2.476GlyArg: 2.476 ± 0.145
4.137GlySer: 4.137 ± 0.177
2.676GlyThr: 2.676 ± 0.128
3.927GlyVal: 3.927 ± 0.177
0.631GlyTrp: 0.631 ± 0.058
2.527GlyTyr: 2.527 ± 0.111
0.0GlyXaa: 0.0 ± 0.0
His
1.435HisAla: 1.435 ± 0.09
0.441HisCys: 0.441 ± 0.044
1.174HisAsp: 1.174 ± 0.082
1.02HisGlu: 1.02 ± 0.077
0.974HisPhe: 0.974 ± 0.08
1.533HisGly: 1.533 ± 0.092
0.866HisHis: 0.866 ± 0.079
2.999HisIle: 2.999 ± 0.137
1.605HisLys: 1.605 ± 0.097
2.025HisLeu: 2.025 ± 0.105
0.554HisMet: 0.554 ± 0.05
1.83HisAsn: 1.83 ± 0.088
1.107HisPro: 1.107 ± 0.066
1.071HisGln: 1.071 ± 0.078
1.066HisArg: 1.066 ± 0.07
1.897HisSer: 1.897 ± 0.093
1.461HisThr: 1.461 ± 0.094
1.451HisVal: 1.451 ± 0.089
0.318HisTrp: 0.318 ± 0.047
0.979HisTyr: 0.979 ± 0.075
0.0HisXaa: 0.0 ± 0.0
Ile
5.931IleAla: 5.931 ± 0.166
1.533IleCys: 1.533 ± 0.093
5.998IleAsp: 5.998 ± 0.17
5.034IleGlu: 5.034 ± 0.183
4.993IlePhe: 4.993 ± 0.209
6.644IleGly: 6.644 ± 0.221
3.163IleHis: 3.163 ± 0.16
12.391IleIle: 12.391 ± 0.331
8.044IleLys: 8.044 ± 0.221
10.935IleLeu: 10.935 ± 0.254
2.558IleMet: 2.558 ± 0.119
8.326IleAsn: 8.326 ± 0.258
4.199IlePro: 4.199 ± 0.15
4.819IleGln: 4.819 ± 0.149
4.501IleArg: 4.501 ± 0.151
8.141IleSer: 8.141 ± 0.222
6.013IleThr: 6.013 ± 0.201
5.737IleVal: 5.737 ± 0.184
1.005IleTrp: 1.005 ± 0.075
4.106IleTyr: 4.106 ± 0.166
0.0IleXaa: 0.0 ± 0.0
Lys
2.358LysAla: 2.358 ± 0.121
0.841LysCys: 0.841 ± 0.073
2.804LysAsp: 2.804 ± 0.11
3.035LysGlu: 3.035 ± 0.155
2.825LysPhe: 2.825 ± 0.129
2.594LysGly: 2.594 ± 0.122
1.682LysHis: 1.682 ± 0.084
9.053LysIle: 9.053 ± 0.212
7.7LysLys: 7.7 ± 0.236
7.592LysLeu: 7.592 ± 0.207
1.784LysMet: 1.784 ± 0.104
6.598LysAsn: 6.598 ± 0.209
1.784LysPro: 1.784 ± 0.094
2.615LysGln: 2.615 ± 0.119
2.712LysArg: 2.712 ± 0.113
4.819LysSer: 4.819 ± 0.179
3.199LysThr: 3.199 ± 0.147
3.384LysVal: 3.384 ± 0.152
0.605LysTrp: 0.605 ± 0.059
3.701LysTyr: 3.701 ± 0.14
0.0LysXaa: 0.0 ± 0.0
Leu
4.322LeuAla: 4.322 ± 0.179
1.558LeuCys: 1.558 ± 0.081
4.706LeuAsp: 4.706 ± 0.174
4.804LeuGlu: 4.804 ± 0.165
4.701LeuPhe: 4.701 ± 0.192
5.45LeuGly: 5.45 ± 0.195
2.707LeuHis: 2.707 ± 0.112
10.186LeuIle: 10.186 ± 0.256
7.418LeuLys: 7.418 ± 0.19
10.12LeuLeu: 10.12 ± 0.286
2.409LeuMet: 2.409 ± 0.105
7.475LeuAsn: 7.475 ± 0.229
3.758LeuPro: 3.758 ± 0.156
3.496LeuGln: 3.496 ± 0.136
4.255LeuArg: 4.255 ± 0.167
8.315LeuSer: 8.315 ± 0.214
4.819LeuThr: 4.819 ± 0.16
5.127LeuVal: 5.127 ± 0.179
0.887LeuTrp: 0.887 ± 0.067
3.988LeuTyr: 3.988 ± 0.165
0.0LeuXaa: 0.0 ± 0.0
Met
1.148MetAla: 1.148 ± 0.076
0.343MetCys: 0.343 ± 0.048
0.923MetAsp: 0.923 ± 0.061
1.066MetGlu: 1.066 ± 0.066
1.0MetPhe: 1.0 ± 0.074
1.507MetGly: 1.507 ± 0.092
0.702MetHis: 0.702 ± 0.06
2.758MetIle: 2.758 ± 0.129
1.712MetLys: 1.712 ± 0.098
2.85MetLeu: 2.85 ± 0.123
0.754MetMet: 0.754 ± 0.06
2.01MetAsn: 2.01 ± 0.094
0.774MetPro: 0.774 ± 0.078
1.0MetGln: 1.0 ± 0.075
1.143MetArg: 1.143 ± 0.081
1.692MetSer: 1.692 ± 0.1
1.082MetThr: 1.082 ± 0.078
1.384MetVal: 1.384 ± 0.101
0.2MetTrp: 0.2 ± 0.035
1.036MetTyr: 1.036 ± 0.075
0.0MetXaa: 0.0 ± 0.0
Asn
2.625AsnAla: 2.625 ± 0.109
0.882AsnCys: 0.882 ± 0.08
3.04AsnAsp: 3.04 ± 0.118
2.533AsnGlu: 2.533 ± 0.115
3.199AsnPhe: 3.199 ± 0.145
2.62AsnGly: 2.62 ± 0.125
1.743AsnHis: 1.743 ± 0.109
9.443AsnIle: 9.443 ± 0.29
5.608AsnLys: 5.608 ± 0.164
5.896AsnLeu: 5.896 ± 0.174
1.733AsnMet: 1.733 ± 0.082
5.998AsnAsn: 5.998 ± 0.229
2.348AsnPro: 2.348 ± 0.119
3.512AsnGln: 3.512 ± 0.151
2.712AsnArg: 2.712 ± 0.122
3.968AsnSer: 3.968 ± 0.147
4.024AsnThr: 4.024 ± 0.191
3.45AsnVal: 3.45 ± 0.136
0.738AsnTrp: 0.738 ± 0.058
2.814AsnTyr: 2.814 ± 0.151
0.0AsnXaa: 0.0 ± 0.0
Pro
1.353ProAla: 1.353 ± 0.086
0.39ProCys: 0.39 ± 0.043
1.492ProAsp: 1.492 ± 0.084
1.81ProGlu: 1.81 ± 0.096
1.323ProPhe: 1.323 ± 0.077
2.225ProGly: 2.225 ± 0.111
0.759ProHis: 0.759 ± 0.064
3.876ProIle: 3.876 ± 0.159
2.286ProLys: 2.286 ± 0.092
2.681ProLeu: 2.681 ± 0.123
0.861ProMet: 0.861 ± 0.067
2.066ProAsn: 2.066 ± 0.117
0.743ProPro: 0.743 ± 0.063
1.015ProGln: 1.015 ± 0.067
0.897ProArg: 0.897 ± 0.074
1.928ProSer: 1.928 ± 0.099
1.84ProThr: 1.84 ± 0.098
2.415ProVal: 2.415 ± 0.106
0.364ProTrp: 0.364 ± 0.048
1.482ProTyr: 1.482 ± 0.101
0.0ProXaa: 0.0 ± 0.0
Gln
1.769GlnAla: 1.769 ± 0.107
0.646GlnCys: 0.646 ± 0.066
1.774GlnAsp: 1.774 ± 0.1
2.404GlnGlu: 2.404 ± 0.115
1.599GlnPhe: 1.599 ± 0.1
2.169GlnGly: 2.169 ± 0.105
1.03GlnHis: 1.03 ± 0.078
3.912GlnIle: 3.912 ± 0.149
3.23GlnLys: 3.23 ± 0.134
4.45GlnLeu: 4.45 ± 0.142
0.646GlnMet: 0.646 ± 0.062
2.358GlnAsn: 2.358 ± 0.107
1.066GlnPro: 1.066 ± 0.078
1.466GlnGln: 1.466 ± 0.1
1.523GlnArg: 1.523 ± 0.099
2.83GlnSer: 2.83 ± 0.127
1.599GlnThr: 1.599 ± 0.099
2.035GlnVal: 2.035 ± 0.101
0.395GlnTrp: 0.395 ± 0.046
2.097GlnTyr: 2.097 ± 0.114
0.0GlnXaa: 0.0 ± 0.0
Arg
2.092ArgAla: 2.092 ± 0.107
0.677ArgCys: 0.677 ± 0.056
1.815ArgAsp: 1.815 ± 0.104
1.753ArgGlu: 1.753 ± 0.107
2.271ArgPhe: 2.271 ± 0.105
2.025ArgGly: 2.025 ± 0.112
0.851ArgHis: 0.851 ± 0.065
4.352ArgIle: 4.352 ± 0.16
2.697ArgLys: 2.697 ± 0.147
4.183ArgLeu: 4.183 ± 0.162
1.148ArgMet: 1.148 ± 0.073
2.502ArgAsn: 2.502 ± 0.131
1.164ArgPro: 1.164 ± 0.08
1.374ArgGln: 1.374 ± 0.093
1.953ArgArg: 1.953 ± 0.117
2.989ArgSer: 2.989 ± 0.147
1.871ArgThr: 1.871 ± 0.093
2.548ArgVal: 2.548 ± 0.127
0.487ArgTrp: 0.487 ± 0.054
2.066ArgTyr: 2.066 ± 0.099
0.0ArgXaa: 0.0 ± 0.0
Ser
3.296SerAla: 3.296 ± 0.154
1.251SerCys: 1.251 ± 0.091
3.466SerAsp: 3.466 ± 0.139
3.378SerGlu: 3.378 ± 0.131
2.886SerPhe: 2.886 ± 0.134
5.28SerGly: 5.28 ± 0.183
1.61SerHis: 1.61 ± 0.091
8.079SerIle: 8.079 ± 0.249
5.029SerLys: 5.029 ± 0.138
6.362SerLeu: 6.362 ± 0.171
1.948SerMet: 1.948 ± 0.117
4.804SerAsn: 4.804 ± 0.163
1.738SerPro: 1.738 ± 0.094
2.307SerGln: 2.307 ± 0.104
2.609SerArg: 2.609 ± 0.129
4.814SerSer: 4.814 ± 0.161
3.389SerThr: 3.389 ± 0.131
4.634SerVal: 4.634 ± 0.203
0.769SerTrp: 0.769 ± 0.069
2.645SerTyr: 2.645 ± 0.122
0.0SerXaa: 0.0 ± 0.0
Thr
2.435ThrAla: 2.435 ± 0.108
0.692ThrCys: 0.692 ± 0.058
2.179ThrAsp: 2.179 ± 0.1
2.169ThrGlu: 2.169 ± 0.11
1.779ThrPhe: 1.779 ± 0.1
3.46ThrGly: 3.46 ± 0.128
1.584ThrHis: 1.584 ± 0.116
5.475ThrIle: 5.475 ± 0.203
2.799ThrLys: 2.799 ± 0.118
5.352ThrLeu: 5.352 ± 0.189
0.964ThrMet: 0.964 ± 0.07
2.876ThrAsn: 2.876 ± 0.138
1.779ThrPro: 1.779 ± 0.106
2.261ThrGln: 2.261 ± 0.102
1.835ThrArg: 1.835 ± 0.098
2.794ThrSer: 2.794 ± 0.119
2.517ThrThr: 2.517 ± 0.14
3.209ThrVal: 3.209 ± 0.121
0.564ThrTrp: 0.564 ± 0.055
1.917ThrTyr: 1.917 ± 0.114
0.0ThrXaa: 0.0 ± 0.0
Val
2.794ValAla: 2.794 ± 0.145
1.03ValCys: 1.03 ± 0.075
3.03ValAsp: 3.03 ± 0.141
2.625ValGlu: 2.625 ± 0.122
2.471ValPhe: 2.471 ± 0.134
3.578ValGly: 3.578 ± 0.154
1.492ValHis: 1.492 ± 0.09
6.321ValIle: 6.321 ± 0.23
3.604ValLys: 3.604 ± 0.133
6.101ValLeu: 6.101 ± 0.211
1.512ValMet: 1.512 ± 0.091
3.271ValAsn: 3.271 ± 0.144
1.866ValPro: 1.866 ± 0.093
1.974ValGln: 1.974 ± 0.101
2.235ValArg: 2.235 ± 0.12
4.373ValSer: 4.373 ± 0.168
2.902ValThr: 2.902 ± 0.139
3.794ValVal: 3.794 ± 0.17
0.569ValTrp: 0.569 ± 0.054
1.974ValTyr: 1.974 ± 0.106
0.0ValXaa: 0.0 ± 0.0
Trp
0.338TrpAla: 0.338 ± 0.039
0.144TrpCys: 0.144 ± 0.026
0.374TrpAsp: 0.374 ± 0.043
0.436TrpGlu: 0.436 ± 0.049
0.523TrpPhe: 0.523 ± 0.055
0.513TrpGly: 0.513 ± 0.062
0.19TrpHis: 0.19 ± 0.029
1.343TrpIle: 1.343 ± 0.089
0.892TrpLys: 0.892 ± 0.074
1.153TrpLeu: 1.153 ± 0.085
0.313TrpMet: 0.313 ± 0.038
0.918TrpAsn: 0.918 ± 0.077
0.328TrpPro: 0.328 ± 0.04
0.379TrpGln: 0.379 ± 0.04
0.441TrpArg: 0.441 ± 0.052
0.646TrpSer: 0.646 ± 0.058
0.282TrpThr: 0.282 ± 0.037
0.579TrpVal: 0.579 ± 0.052
0.097TrpTrp: 0.097 ± 0.025
0.482TrpTyr: 0.482 ± 0.05
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.912TyrAla: 1.912 ± 0.097
0.892TyrCys: 0.892 ± 0.064
2.112TyrAsp: 2.112 ± 0.101
1.62TyrGlu: 1.62 ± 0.104
1.907TyrPhe: 1.907 ± 0.104
2.481TyrGly: 2.481 ± 0.126
1.318TyrHis: 1.318 ± 0.083
4.317TyrIle: 4.317 ± 0.184
2.753TyrLys: 2.753 ± 0.117
4.255TyrLeu: 4.255 ± 0.155
0.918TyrMet: 0.918 ± 0.061
2.989TyrAsn: 2.989 ± 0.146
1.476TyrPro: 1.476 ± 0.091
2.092TyrGln: 2.092 ± 0.112
1.671TyrArg: 1.671 ± 0.091
2.943TyrSer: 2.943 ± 0.125
2.01TyrThr: 2.01 ± 0.112
2.153TyrVal: 2.153 ± 0.092
0.528TyrTrp: 0.528 ± 0.054
1.979TyrTyr: 1.979 ± 0.116
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 583 proteins (195064 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski