Amino acid dipepetide frequency for Gordonia phage Turuncu

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.477AlaAla: 12.477 ± 1.155
0.806AlaCys: 0.806 ± 0.204
7.116AlaAsp: 7.116 ± 0.783
8.112AlaGlu: 8.112 ± 0.653
3.321AlaPhe: 3.321 ± 0.428
8.492AlaGly: 8.492 ± 0.914
2.467AlaHis: 2.467 ± 0.47
4.602AlaIle: 4.602 ± 0.65
4.981AlaLys: 4.981 ± 0.505
7.496AlaLeu: 7.496 ± 0.957
2.799AlaMet: 2.799 ± 0.324
2.941AlaAsn: 2.941 ± 0.376
3.938AlaPro: 3.938 ± 0.465
3.7AlaGln: 3.7 ± 0.562
6.404AlaArg: 6.404 ± 0.611
5.171AlaSer: 5.171 ± 0.549
6.547AlaThr: 6.547 ± 0.691
7.211AlaVal: 7.211 ± 0.584
1.566AlaTrp: 1.566 ± 0.288
2.372AlaTyr: 2.372 ± 0.349
0.0AlaXaa: 0.0 ± 0.0
Cys
0.474CysAla: 0.474 ± 0.153
0.142CysCys: 0.142 ± 0.086
0.664CysAsp: 0.664 ± 0.242
0.617CysGlu: 0.617 ± 0.162
0.047CysPhe: 0.047 ± 0.054
1.233CysGly: 1.233 ± 0.316
0.427CysHis: 0.427 ± 0.169
0.427CysIle: 0.427 ± 0.152
0.19CysLys: 0.19 ± 0.105
0.617CysLeu: 0.617 ± 0.211
0.047CysMet: 0.047 ± 0.05
0.142CysAsn: 0.142 ± 0.075
0.617CysPro: 0.617 ± 0.223
0.332CysGln: 0.332 ± 0.119
0.332CysArg: 0.332 ± 0.137
0.332CysSer: 0.332 ± 0.148
0.427CysThr: 0.427 ± 0.16
0.569CysVal: 0.569 ± 0.167
0.237CysTrp: 0.237 ± 0.095
0.19CysTyr: 0.19 ± 0.146
0.0CysXaa: 0.0 ± 0.0
Asp
6.642AspAla: 6.642 ± 0.733
0.522AspCys: 0.522 ± 0.182
6.31AspAsp: 6.31 ± 1.047
4.839AspGlu: 4.839 ± 0.583
2.325AspPhe: 2.325 ± 0.341
6.784AspGly: 6.784 ± 0.627
1.091AspHis: 1.091 ± 0.223
3.084AspIle: 3.084 ± 0.494
2.087AspLys: 2.087 ± 0.324
4.981AspLeu: 4.981 ± 0.493
1.376AspMet: 1.376 ± 0.263
2.23AspAsn: 2.23 ± 0.388
5.124AspPro: 5.124 ± 0.533
2.325AspGln: 2.325 ± 0.304
4.697AspArg: 4.697 ± 0.576
2.941AspSer: 2.941 ± 0.42
4.032AspThr: 4.032 ± 0.523
4.839AspVal: 4.839 ± 0.515
1.471AspTrp: 1.471 ± 0.231
2.135AspTyr: 2.135 ± 0.365
0.0AspXaa: 0.0 ± 0.0
Glu
6.167GluAla: 6.167 ± 0.654
0.332GluCys: 0.332 ± 0.13
3.463GluAsp: 3.463 ± 0.442
4.032GluGlu: 4.032 ± 0.613
2.657GluPhe: 2.657 ± 0.461
4.412GluGly: 4.412 ± 0.549
1.898GluHis: 1.898 ± 0.36
4.08GluIle: 4.08 ± 0.425
2.846GluLys: 2.846 ± 0.417
5.74GluLeu: 5.74 ± 0.695
1.566GluMet: 1.566 ± 0.194
2.182GluAsn: 2.182 ± 0.28
2.894GluPro: 2.894 ± 0.457
2.277GluGln: 2.277 ± 0.299
4.222GluArg: 4.222 ± 0.536
3.321GluSer: 3.321 ± 0.398
4.127GluThr: 4.127 ± 0.51
4.744GluVal: 4.744 ± 0.56
1.044GluTrp: 1.044 ± 0.216
1.945GluTyr: 1.945 ± 0.31
0.0GluXaa: 0.0 ± 0.0
Phe
2.087PheAla: 2.087 ± 0.267
0.38PheCys: 0.38 ± 0.141
3.179PheAsp: 3.179 ± 0.406
2.087PheGlu: 2.087 ± 0.293
0.759PhePhe: 0.759 ± 0.212
2.752PheGly: 2.752 ± 0.271
0.712PheHis: 0.712 ± 0.176
1.613PheIle: 1.613 ± 0.261
0.806PheLys: 0.806 ± 0.137
2.514PheLeu: 2.514 ± 0.397
0.664PheMet: 0.664 ± 0.184
0.759PheAsn: 0.759 ± 0.195
1.281PhePro: 1.281 ± 0.297
1.233PheGln: 1.233 ± 0.245
2.135PheArg: 2.135 ± 0.29
1.755PheSer: 1.755 ± 0.259
1.898PheThr: 1.898 ± 0.301
2.135PheVal: 2.135 ± 0.361
0.806PheTrp: 0.806 ± 0.2
1.376PheTyr: 1.376 ± 0.204
0.0PheXaa: 0.0 ± 0.0
Gly
8.539GlyAla: 8.539 ± 0.832
0.712GlyCys: 0.712 ± 0.207
6.025GlyAsp: 6.025 ± 0.467
4.602GlyGlu: 4.602 ± 0.579
2.941GlyPhe: 2.941 ± 0.371
8.824GlyGly: 8.824 ± 1.427
2.04GlyHis: 2.04 ± 0.432
4.365GlyIle: 4.365 ± 0.579
3.605GlyLys: 3.605 ± 0.47
6.689GlyLeu: 6.689 ± 0.492
1.803GlyMet: 1.803 ± 0.34
2.704GlyAsn: 2.704 ± 0.357
4.365GlyPro: 4.365 ± 0.551
3.131GlyGln: 3.131 ± 0.479
6.31GlyArg: 6.31 ± 0.618
5.835GlySer: 5.835 ± 0.608
5.313GlyThr: 5.313 ± 0.628
5.883GlyVal: 5.883 ± 0.591
1.755GlyTrp: 1.755 ± 0.286
2.846GlyTyr: 2.846 ± 0.355
0.0GlyXaa: 0.0 ± 0.0
His
1.803HisAla: 1.803 ± 0.295
0.095HisCys: 0.095 ± 0.098
1.328HisAsp: 1.328 ± 0.322
0.712HisGlu: 0.712 ± 0.182
0.949HisPhe: 0.949 ± 0.241
1.613HisGly: 1.613 ± 0.367
0.617HisHis: 0.617 ± 0.22
0.759HisIle: 0.759 ± 0.172
0.427HisLys: 0.427 ± 0.119
1.566HisLeu: 1.566 ± 0.343
0.617HisMet: 0.617 ± 0.179
0.38HisAsn: 0.38 ± 0.111
1.518HisPro: 1.518 ± 0.313
0.569HisGln: 0.569 ± 0.175
1.993HisArg: 1.993 ± 0.346
1.044HisSer: 1.044 ± 0.208
1.423HisThr: 1.423 ± 0.296
1.613HisVal: 1.613 ± 0.264
0.522HisTrp: 0.522 ± 0.127
0.854HisTyr: 0.854 ± 0.196
0.0HisXaa: 0.0 ± 0.0
Ile
5.645IleAla: 5.645 ± 0.664
0.332IleCys: 0.332 ± 0.148
3.7IleAsp: 3.7 ± 0.453
4.08IleGlu: 4.08 ± 0.494
1.233IlePhe: 1.233 ± 0.276
4.839IleGly: 4.839 ± 0.637
1.091IleHis: 1.091 ± 0.245
2.087IleIle: 2.087 ± 0.314
1.993IleLys: 1.993 ± 0.254
3.273IleLeu: 3.273 ± 0.403
0.854IleMet: 0.854 ± 0.195
2.04IleAsn: 2.04 ± 0.415
2.799IlePro: 2.799 ± 0.343
1.423IleGln: 1.423 ± 0.269
3.036IleArg: 3.036 ± 0.396
2.562IleSer: 2.562 ± 0.321
3.511IleThr: 3.511 ± 0.422
3.368IleVal: 3.368 ± 0.38
1.044IleTrp: 1.044 ± 0.218
1.281IleTyr: 1.281 ± 0.248
0.0IleXaa: 0.0 ± 0.0
Lys
3.273LysAla: 3.273 ± 0.497
0.332LysCys: 0.332 ± 0.147
2.562LysAsp: 2.562 ± 0.385
1.898LysGlu: 1.898 ± 0.331
1.376LysPhe: 1.376 ± 0.268
3.605LysGly: 3.605 ± 0.406
0.569LysHis: 0.569 ± 0.164
2.325LysIle: 2.325 ± 0.286
2.277LysLys: 2.277 ± 0.401
3.368LysLeu: 3.368 ± 0.452
0.996LysMet: 0.996 ± 0.295
1.281LysAsn: 1.281 ± 0.246
2.419LysPro: 2.419 ± 0.345
1.376LysGln: 1.376 ± 0.284
3.131LysArg: 3.131 ± 0.374
1.708LysSer: 1.708 ± 0.309
2.704LysThr: 2.704 ± 0.352
3.558LysVal: 3.558 ± 0.383
0.759LysTrp: 0.759 ± 0.212
0.901LysTyr: 0.901 ± 0.203
0.0LysXaa: 0.0 ± 0.0
Leu
7.59LeuAla: 7.59 ± 0.932
0.949LeuCys: 0.949 ± 0.285
5.503LeuAsp: 5.503 ± 0.527
3.89LeuGlu: 3.89 ± 0.424
2.04LeuPhe: 2.04 ± 0.301
6.499LeuGly: 6.499 ± 0.645
1.186LeuHis: 1.186 ± 0.206
3.463LeuIle: 3.463 ± 0.389
2.799LeuLys: 2.799 ± 0.347
5.456LeuLeu: 5.456 ± 0.465
1.566LeuMet: 1.566 ± 0.271
2.23LeuAsn: 2.23 ± 0.218
4.365LeuPro: 4.365 ± 0.478
2.325LeuGln: 2.325 ± 0.395
5.171LeuArg: 5.171 ± 0.439
4.839LeuSer: 4.839 ± 0.433
5.361LeuThr: 5.361 ± 0.584
5.645LeuVal: 5.645 ± 0.553
1.139LeuTrp: 1.139 ± 0.235
2.04LeuTyr: 2.04 ± 0.302
0.0LeuXaa: 0.0 ± 0.0
Met
3.036MetAla: 3.036 ± 0.436
0.142MetCys: 0.142 ± 0.082
1.566MetAsp: 1.566 ± 0.24
1.471MetGlu: 1.471 ± 0.236
0.949MetPhe: 0.949 ± 0.229
1.281MetGly: 1.281 ± 0.311
0.19MetHis: 0.19 ± 0.12
0.949MetIle: 0.949 ± 0.232
0.949MetLys: 0.949 ± 0.221
1.66MetLeu: 1.66 ± 0.265
0.38MetMet: 0.38 ± 0.16
0.569MetAsn: 0.569 ± 0.155
1.566MetPro: 1.566 ± 0.269
0.522MetGln: 0.522 ± 0.153
1.376MetArg: 1.376 ± 0.253
2.182MetSer: 2.182 ± 0.358
1.566MetThr: 1.566 ± 0.271
0.996MetVal: 0.996 ± 0.182
0.332MetTrp: 0.332 ± 0.144
0.712MetTyr: 0.712 ± 0.182
0.0MetXaa: 0.0 ± 0.0
Asn
2.941AsnAla: 2.941 ± 0.373
0.285AsnCys: 0.285 ± 0.115
2.372AsnAsp: 2.372 ± 0.38
2.087AsnGlu: 2.087 ± 0.291
1.233AsnPhe: 1.233 ± 0.227
3.273AsnGly: 3.273 ± 0.419
0.617AsnHis: 0.617 ± 0.148
1.518AsnIle: 1.518 ± 0.371
1.091AsnLys: 1.091 ± 0.236
1.66AsnLeu: 1.66 ± 0.311
0.569AsnMet: 0.569 ± 0.155
0.949AsnAsn: 0.949 ± 0.208
2.372AsnPro: 2.372 ± 0.325
0.806AsnGln: 0.806 ± 0.168
1.898AsnArg: 1.898 ± 0.278
1.566AsnSer: 1.566 ± 0.29
1.898AsnThr: 1.898 ± 0.331
2.657AsnVal: 2.657 ± 0.363
1.091AsnTrp: 1.091 ± 0.257
1.044AsnTyr: 1.044 ± 0.189
0.0AsnXaa: 0.0 ± 0.0
Pro
5.598ProAla: 5.598 ± 0.609
0.19ProCys: 0.19 ± 0.089
4.175ProAsp: 4.175 ± 0.411
4.365ProGlu: 4.365 ± 0.523
1.518ProPhe: 1.518 ± 0.21
5.218ProGly: 5.218 ± 0.568
0.949ProHis: 0.949 ± 0.161
3.084ProIle: 3.084 ± 0.318
2.419ProLys: 2.419 ± 0.345
3.938ProLeu: 3.938 ± 0.539
1.139ProMet: 1.139 ± 0.22
1.755ProAsn: 1.755 ± 0.228
2.562ProPro: 2.562 ± 0.35
1.281ProGln: 1.281 ± 0.216
3.938ProArg: 3.938 ± 0.623
2.752ProSer: 2.752 ± 0.319
3.036ProThr: 3.036 ± 0.431
4.27ProVal: 4.27 ± 0.471
0.996ProTrp: 0.996 ± 0.177
0.854ProTyr: 0.854 ± 0.199
0.0ProXaa: 0.0 ± 0.0
Gln
3.368GlnAla: 3.368 ± 0.558
0.237GlnCys: 0.237 ± 0.115
1.755GlnAsp: 1.755 ± 0.263
1.85GlnGlu: 1.85 ± 0.312
0.806GlnPhe: 0.806 ± 0.185
2.087GlnGly: 2.087 ± 0.355
0.474GlnHis: 0.474 ± 0.129
2.04GlnIle: 2.04 ± 0.257
1.091GlnLys: 1.091 ± 0.202
2.657GlnLeu: 2.657 ± 0.364
1.186GlnMet: 1.186 ± 0.26
1.471GlnAsn: 1.471 ± 0.344
1.708GlnPro: 1.708 ± 0.275
1.518GlnGln: 1.518 ± 0.319
2.752GlnArg: 2.752 ± 0.354
1.755GlnSer: 1.755 ± 0.313
1.85GlnThr: 1.85 ± 0.261
2.704GlnVal: 2.704 ± 0.335
0.664GlnTrp: 0.664 ± 0.167
0.759GlnTyr: 0.759 ± 0.152
0.0GlnXaa: 0.0 ± 0.0
Arg
7.069ArgAla: 7.069 ± 0.686
0.901ArgCys: 0.901 ± 0.245
4.365ArgAsp: 4.365 ± 0.507
5.029ArgGlu: 5.029 ± 0.502
2.419ArgPhe: 2.419 ± 0.383
5.93ArgGly: 5.93 ± 0.571
1.708ArgHis: 1.708 ± 0.339
3.558ArgIle: 3.558 ± 0.303
3.558ArgLys: 3.558 ± 0.403
4.934ArgLeu: 4.934 ± 0.569
2.135ArgMet: 2.135 ± 0.274
2.467ArgAsn: 2.467 ± 0.309
3.131ArgPro: 3.131 ± 0.458
2.894ArgGln: 2.894 ± 0.385
7.733ArgArg: 7.733 ± 0.905
3.463ArgSer: 3.463 ± 0.549
4.127ArgThr: 4.127 ± 0.399
4.602ArgVal: 4.602 ± 0.402
1.708ArgTrp: 1.708 ± 0.355
1.376ArgTyr: 1.376 ± 0.233
0.0ArgXaa: 0.0 ± 0.0
Ser
7.211SerAla: 7.211 ± 0.707
0.427SerCys: 0.427 ± 0.144
3.795SerAsp: 3.795 ± 0.383
3.226SerGlu: 3.226 ± 0.383
1.376SerPhe: 1.376 ± 0.275
5.645SerGly: 5.645 ± 0.555
0.759SerHis: 0.759 ± 0.204
2.467SerIle: 2.467 ± 0.368
2.087SerLys: 2.087 ± 0.272
3.7SerLeu: 3.7 ± 0.326
1.566SerMet: 1.566 ± 0.312
1.518SerAsn: 1.518 ± 0.282
2.514SerPro: 2.514 ± 0.332
1.708SerGln: 1.708 ± 0.282
4.127SerArg: 4.127 ± 0.487
2.894SerSer: 2.894 ± 0.394
3.226SerThr: 3.226 ± 0.407
3.321SerVal: 3.321 ± 0.428
1.518SerTrp: 1.518 ± 0.273
1.471SerTyr: 1.471 ± 0.262
0.0SerXaa: 0.0 ± 0.0
Thr
6.642ThrAla: 6.642 ± 0.616
0.38ThrCys: 0.38 ± 0.141
3.273ThrAsp: 3.273 ± 0.4
3.226ThrGlu: 3.226 ± 0.416
1.85ThrPhe: 1.85 ± 0.291
6.262ThrGly: 6.262 ± 0.644
1.186ThrHis: 1.186 ± 0.251
4.08ThrIle: 4.08 ± 0.471
2.752ThrLys: 2.752 ± 0.353
4.886ThrLeu: 4.886 ± 0.468
1.091ThrMet: 1.091 ± 0.199
2.135ThrAsn: 2.135 ± 0.305
3.985ThrPro: 3.985 ± 0.463
1.566ThrGln: 1.566 ± 0.232
4.032ThrArg: 4.032 ± 0.408
3.321ThrSer: 3.321 ± 0.354
4.554ThrThr: 4.554 ± 0.517
5.313ThrVal: 5.313 ± 0.51
1.186ThrTrp: 1.186 ± 0.225
1.755ThrTyr: 1.755 ± 0.356
0.0ThrXaa: 0.0 ± 0.0
Val
7.496ValAla: 7.496 ± 0.717
0.38ValCys: 0.38 ± 0.137
5.456ValAsp: 5.456 ± 0.492
4.934ValGlu: 4.934 ± 0.476
1.898ValPhe: 1.898 ± 0.286
6.499ValGly: 6.499 ± 0.653
1.471ValHis: 1.471 ± 0.26
4.127ValIle: 4.127 ± 0.376
2.752ValLys: 2.752 ± 0.43
4.507ValLeu: 4.507 ± 0.5
1.471ValMet: 1.471 ± 0.253
2.514ValAsn: 2.514 ± 0.32
3.89ValPro: 3.89 ± 0.418
2.562ValGln: 2.562 ± 0.352
6.025ValArg: 6.025 ± 0.431
3.795ValSer: 3.795 ± 0.364
4.934ValThr: 4.934 ± 0.447
5.551ValVal: 5.551 ± 0.553
1.139ValTrp: 1.139 ± 0.258
1.423ValTyr: 1.423 ± 0.314
0.0ValXaa: 0.0 ± 0.0
Trp
1.708TrpAla: 1.708 ± 0.288
0.285TrpCys: 0.285 ± 0.097
1.66TrpAsp: 1.66 ± 0.261
1.186TrpGlu: 1.186 ± 0.242
0.569TrpPhe: 0.569 ± 0.179
0.996TrpGly: 0.996 ± 0.276
0.522TrpHis: 0.522 ± 0.164
0.996TrpIle: 0.996 ± 0.217
0.901TrpLys: 0.901 ± 0.199
1.85TrpLeu: 1.85 ± 0.368
0.237TrpMet: 0.237 ± 0.102
0.759TrpAsn: 0.759 ± 0.216
0.664TrpPro: 0.664 ± 0.195
0.712TrpGln: 0.712 ± 0.202
1.044TrpArg: 1.044 ± 0.246
1.803TrpSer: 1.803 ± 0.361
1.233TrpThr: 1.233 ± 0.213
2.182TrpVal: 2.182 ± 0.359
0.617TrpTrp: 0.617 ± 0.192
0.237TrpTyr: 0.237 ± 0.106
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.752TyrAla: 2.752 ± 0.321
0.237TyrCys: 0.237 ± 0.108
1.613TyrAsp: 1.613 ± 0.276
1.708TyrGlu: 1.708 ± 0.276
0.664TyrPhe: 0.664 ± 0.166
2.04TyrGly: 2.04 ± 0.332
0.427TyrHis: 0.427 ± 0.168
0.569TyrIle: 0.569 ± 0.15
0.806TyrLys: 0.806 ± 0.184
2.562TyrLeu: 2.562 ± 0.448
0.285TyrMet: 0.285 ± 0.126
0.901TyrAsn: 0.901 ± 0.182
2.325TyrPro: 2.325 ± 0.328
0.474TyrGln: 0.474 ± 0.139
2.752TyrArg: 2.752 ± 0.312
1.518TyrSer: 1.518 ± 0.254
1.708TyrThr: 1.708 ± 0.279
1.66TyrVal: 1.66 ± 0.317
0.569TyrTrp: 0.569 ± 0.188
0.569TyrTyr: 0.569 ± 0.173
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 94 proteins (21080 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski