Amino acid dipepetide frequency for Chryseobacterium taklimakanense

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.038AlaAla: 5.038 ± 0.099	0.51AlaCys: 0.51 ± 0.03	3.742AlaAsp: 3.742 ± 0.08	5.179AlaGlu: 5.179 ± 0.101	3.212AlaPhe: 3.212 ± 0.071	4.494AlaGly: 4.494 ± 0.078	1.074AlaHis: 1.074 ± 0.035	4.444AlaIle: 4.444 ± 0.071	5.402AlaLys: 5.402 ± 0.1	5.967AlaLeu: 5.967 ± 0.095	1.737AlaMet: 1.737 ± 0.049	3.354AlaAsn: 3.354 ± 0.076	1.844AlaPro: 1.844 ± 0.05	2.643AlaGln: 2.643 ± 0.061	2.204AlaArg: 2.204 ± 0.057	3.519AlaSer: 3.519 ± 0.073	3.344AlaThr: 3.344 ± 0.067	4.733AlaVal: 4.733 ± 0.081	0.551AlaTrp: 0.551 ± 0.025	2.283AlaTyr: 2.283 ± 0.059	0.0AlaXaa: 0.0 ± 0.0
Cys	0.462CysAla: 0.462 ± 0.028	0.097CysCys: 0.097 ± 0.012	0.376CysAsp: 0.376 ± 0.022	0.435CysGlu: 0.435 ± 0.025	0.393CysPhe: 0.393 ± 0.021	0.655CysGly: 0.655 ± 0.033	0.178CysHis: 0.178 ± 0.016	0.527CysIle: 0.527 ± 0.027	0.49CysLys: 0.49 ± 0.026	0.555CysLeu: 0.555 ± 0.026	0.17CysMet: 0.17 ± 0.015	0.361CysAsn: 0.361 ± 0.023	0.334CysPro: 0.334 ± 0.025	0.19CysGln: 0.19 ± 0.016	0.309CysArg: 0.309 ± 0.017	0.521CysSer: 0.521 ± 0.028	0.355CysThr: 0.355 ± 0.025	0.428CysVal: 0.428 ± 0.022	0.048CysTrp: 0.048 ± 0.008	0.281CysTyr: 0.281 ± 0.023	0.0CysXaa: 0.0 ± 0.0
Asp	3.616AspAla: 3.616 ± 0.065	0.369AspCys: 0.369 ± 0.022	2.839AspAsp: 2.839 ± 0.069	4.503AspGlu: 4.503 ± 0.088	3.914AspPhe: 3.914 ± 0.079	3.358AspGly: 3.358 ± 0.069	0.895AspHis: 0.895 ± 0.031	3.991AspIle: 3.991 ± 0.079	4.202AspLys: 4.202 ± 0.073	5.368AspLeu: 5.368 ± 0.085	1.15AspMet: 1.15 ± 0.039	2.707AspAsn: 2.707 ± 0.072	1.601AspPro: 1.601 ± 0.046	1.521AspGln: 1.521 ± 0.045	2.139AspArg: 2.139 ± 0.051	2.925AspSer: 2.925 ± 0.068	2.338AspThr: 2.338 ± 0.054	3.394AspVal: 3.394 ± 0.064	0.757AspTrp: 0.757 ± 0.031	2.833AspTyr: 2.833 ± 0.065	0.0AspXaa: 0.0 ± 0.0
Glu	4.284GluAla: 4.284 ± 0.089	0.356GluCys: 0.356 ± 0.024	3.61GluAsp: 3.61 ± 0.076	5.433GluGlu: 5.433 ± 0.114	3.538GluPhe: 3.538 ± 0.068	3.726GluGly: 3.726 ± 0.081	1.181GluHis: 1.181 ± 0.038	6.41GluIle: 6.41 ± 0.108	7.535GluLys: 7.535 ± 0.117	6.086GluLeu: 6.086 ± 0.109	1.924GluMet: 1.924 ± 0.051	5.62GluAsn: 5.62 ± 0.1	1.704GluPro: 1.704 ± 0.048	2.451GluGln: 2.451 ± 0.062	2.773GluArg: 2.773 ± 0.067	3.233GluSer: 3.233 ± 0.065	3.824GluThr: 3.824 ± 0.069	4.393GluVal: 4.393 ± 0.077	0.664GluTrp: 0.664 ± 0.033	2.554GluTyr: 2.554 ± 0.061	0.0GluXaa: 0.0 ± 0.0
Phe	3.582PheAla: 3.582 ± 0.064	0.44PheCys: 0.44 ± 0.023	3.176PheAsp: 3.176 ± 0.066	3.567PheGlu: 3.567 ± 0.072	2.953PhePhe: 2.953 ± 0.08	3.718PheGly: 3.718 ± 0.084	0.937PheHis: 0.937 ± 0.037	3.879PheIle: 3.879 ± 0.08	3.584PheLys: 3.584 ± 0.069	5.05PheLeu: 5.05 ± 0.096	1.283PheMet: 1.283 ± 0.04	3.026PheAsn: 3.026 ± 0.07	1.989PhePro: 1.989 ± 0.055	1.693PheGln: 1.693 ± 0.043	2.155PheArg: 2.155 ± 0.061	4.057PheSer: 4.057 ± 0.079	2.999PheThr: 2.999 ± 0.071	3.187PheVal: 3.187 ± 0.063	0.663PheTrp: 0.663 ± 0.03	2.331PheTyr: 2.331 ± 0.065	0.0PheXaa: 0.0 ± 0.0
Gly	4.041GlyAla: 4.041 ± 0.087	0.517GlyCys: 0.517 ± 0.027	3.182GlyAsp: 3.182 ± 0.067	3.878GlyGlu: 3.878 ± 0.078	3.571GlyPhe: 3.571 ± 0.069	4.393GlyGly: 4.393 ± 0.1	1.104GlyHis: 1.104 ± 0.035	5.364GlyIle: 5.364 ± 0.089	5.975GlyLys: 5.975 ± 0.088	5.431GlyLeu: 5.431 ± 0.093	1.686GlyMet: 1.686 ± 0.05	3.816GlyAsn: 3.816 ± 0.081	1.177GlyPro: 1.177 ± 0.039	1.948GlyGln: 1.948 ± 0.045	2.347GlyArg: 2.347 ± 0.071	3.631GlySer: 3.631 ± 0.086	3.656GlyThr: 3.656 ± 0.064	3.889GlyVal: 3.889 ± 0.079	0.707GlyTrp: 0.707 ± 0.031	2.738GlyTyr: 2.738 ± 0.062	0.0GlyXaa: 0.0 ± 0.0
His	0.952HisAla: 0.952 ± 0.035	0.198HisCys: 0.198 ± 0.015	0.892HisAsp: 0.892 ± 0.037	0.995HisGlu: 0.995 ± 0.042	1.161HisPhe: 1.161 ± 0.049	1.076HisGly: 1.076 ± 0.039	0.532HisHis: 0.532 ± 0.027	1.29HisIle: 1.29 ± 0.037	1.202HisLys: 1.202 ± 0.045	1.728HisLeu: 1.728 ± 0.05	0.336HisMet: 0.336 ± 0.024	0.946HisAsn: 0.946 ± 0.037	0.897HisPro: 0.897 ± 0.033	0.737HisGln: 0.737 ± 0.03	0.739HisArg: 0.739 ± 0.035	1.219HisSer: 1.219 ± 0.037	0.848HisThr: 0.848 ± 0.035	0.745HisVal: 0.745 ± 0.029	0.234HisTrp: 0.234 ± 0.018	0.849HisTyr: 0.849 ± 0.034	0.0HisXaa: 0.0 ± 0.0
Ile	5.182IleAla: 5.182 ± 0.087	0.635IleCys: 0.635 ± 0.032	4.353IleAsp: 4.353 ± 0.07	5.025IleGlu: 5.025 ± 0.084	4.01IlePhe: 4.01 ± 0.081	4.591IleGly: 4.591 ± 0.091	1.302IleHis: 1.302 ± 0.038	5.578IleIle: 5.578 ± 0.095	5.488IleLys: 5.488 ± 0.088	7.182IleLeu: 7.182 ± 0.107	1.394IleMet: 1.394 ± 0.044	4.108IleAsn: 4.108 ± 0.069	3.245IlePro: 3.245 ± 0.066	2.495IleGln: 2.495 ± 0.058	2.74IleArg: 2.74 ± 0.061	5.787IleSer: 5.787 ± 0.083	4.026IleThr: 4.026 ± 0.064	4.345IleVal: 4.345 ± 0.073	0.637IleTrp: 0.637 ± 0.029	2.745IleTyr: 2.745 ± 0.059	0.0IleXaa: 0.0 ± 0.0
Lys	4.97LysAla: 4.97 ± 0.093	0.421LysCys: 0.421 ± 0.024	4.796LysAsp: 4.796 ± 0.09	6.252LysGlu: 6.252 ± 0.108	3.875LysPhe: 3.875 ± 0.065	4.486LysGly: 4.486 ± 0.08	1.343LysHis: 1.343 ± 0.043	7.495LysIle: 7.495 ± 0.104	7.369LysLys: 7.369 ± 0.115	6.872LysLeu: 6.872 ± 0.103	2.504LysMet: 2.504 ± 0.05	6.184LysAsn: 6.184 ± 0.076	2.999LysPro: 2.999 ± 0.065	2.748LysGln: 2.748 ± 0.058	2.842LysArg: 2.842 ± 0.067	4.928LysSer: 4.928 ± 0.086	4.976LysThr: 4.976 ± 0.077	4.774LysVal: 4.774 ± 0.103	0.748LysTrp: 0.748 ± 0.036	3.345LysTyr: 3.345 ± 0.073	0.0LysXaa: 0.0 ± 0.0
Leu	5.997LeuAla: 5.997 ± 0.102	0.641LeuCys: 0.641 ± 0.029	4.696LeuAsp: 4.696 ± 0.077	6.083LeuGlu: 6.083 ± 0.09	4.613LeuPhe: 4.613 ± 0.107	5.838LeuGly: 5.838 ± 0.106	1.597LeuHis: 1.597 ± 0.044	6.329LeuIle: 6.329 ± 0.106	8.267LeuLys: 8.267 ± 0.11	8.137LeuLeu: 8.137 ± 0.125	2.37LeuMet: 2.37 ± 0.05	5.509LeuAsn: 5.509 ± 0.095	3.603LeuPro: 3.603 ± 0.075	3.525LeuGln: 3.525 ± 0.076	3.372LeuArg: 3.372 ± 0.07	6.153LeuSer: 6.153 ± 0.085	4.597LeuThr: 4.597 ± 0.077	5.126LeuVal: 5.126 ± 0.076	0.782LeuTrp: 0.782 ± 0.037	3.016LeuTyr: 3.016 ± 0.068	0.0LeuXaa: 0.0 ± 0.0
Met	1.689MetAla: 1.689 ± 0.048	0.141MetCys: 0.141 ± 0.014	1.264MetAsp: 1.264 ± 0.04	1.706MetGlu: 1.706 ± 0.047	1.025MetPhe: 1.025 ± 0.039	1.498MetGly: 1.498 ± 0.05	0.405MetHis: 0.405 ± 0.022	1.717MetIle: 1.717 ± 0.043	2.654MetLys: 2.654 ± 0.052	2.21MetLeu: 2.21 ± 0.058	0.816MetMet: 0.816 ± 0.039	1.568MetAsn: 1.568 ± 0.053	0.966MetPro: 0.966 ± 0.036	0.926MetGln: 0.926 ± 0.035	0.932MetArg: 0.932 ± 0.033	1.483MetSer: 1.483 ± 0.036	1.257MetThr: 1.257 ± 0.038	1.51MetVal: 1.51 ± 0.046	0.185MetTrp: 0.185 ± 0.016	0.698MetTyr: 0.698 ± 0.03	0.0MetXaa: 0.0 ± 0.0
Asn	3.905AsnAla: 3.905 ± 0.075	0.423AsnCys: 0.423 ± 0.026	2.896AsnAsp: 2.896 ± 0.065	3.859AsnGlu: 3.859 ± 0.076	3.69AsnPhe: 3.69 ± 0.069	3.712AsnGly: 3.712 ± 0.077	1.128AsnHis: 1.128 ± 0.034	4.765AsnIle: 4.765 ± 0.071	4.095AsnLys: 4.095 ± 0.071	5.833AsnLeu: 5.833 ± 0.097	1.23AsnMet: 1.23 ± 0.041	3.315AsnAsn: 3.315 ± 0.076	2.901AsnPro: 2.901 ± 0.059	2.282AsnGln: 2.282 ± 0.059	2.363AsnArg: 2.363 ± 0.059	3.922AsnSer: 3.922 ± 0.084	2.902AsnThr: 2.902 ± 0.068	3.463AsnVal: 3.463 ± 0.075	0.789AsnTrp: 0.789 ± 0.033	2.884AsnTyr: 2.884 ± 0.063	0.0AsnXaa: 0.0 ± 0.0
Pro	2.3ProAla: 2.3 ± 0.06	0.19ProCys: 0.19 ± 0.014	2.064ProAsp: 2.064 ± 0.052	3.396ProGlu: 3.396 ± 0.069	1.851ProPhe: 1.851 ± 0.051	1.96ProGly: 1.96 ± 0.05	0.625ProHis: 0.625 ± 0.032	2.1ProIle: 2.1 ± 0.054	2.892ProLys: 2.892 ± 0.058	2.838ProLeu: 2.838 ± 0.063	0.835ProMet: 0.835 ± 0.039	2.076ProAsn: 2.076 ± 0.051	0.782ProPro: 0.782 ± 0.036	1.416ProGln: 1.416 ± 0.047	1.015ProArg: 1.015 ± 0.035	2.022ProSer: 2.022 ± 0.046	1.841ProThr: 1.841 ± 0.048	2.788ProVal: 2.788 ± 0.063	0.284ProTrp: 0.284 ± 0.022	1.458ProTyr: 1.458 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	1.856GlnAla: 1.856 ± 0.05	0.171GlnCys: 0.171 ± 0.015	1.651GlnAsp: 1.651 ± 0.053	2.386GlnGlu: 2.386 ± 0.055	1.737GlnPhe: 1.737 ± 0.043	1.746GlnGly: 1.746 ± 0.054	0.598GlnHis: 0.598 ± 0.028	2.776GlnIle: 2.776 ± 0.057	3.816GlnLys: 3.816 ± 0.075	3.173GlnLeu: 3.173 ± 0.065	1.002GlnMet: 1.002 ± 0.036	2.863GlnAsn: 2.863 ± 0.061	1.246GlnPro: 1.246 ± 0.042	1.659GlnGln: 1.659 ± 0.053	1.476GlnArg: 1.476 ± 0.044	1.825GlnSer: 1.825 ± 0.059	1.927GlnThr: 1.927 ± 0.051	1.823GlnVal: 1.823 ± 0.048	0.352GlnTrp: 0.352 ± 0.019	1.441GlnTyr: 1.441 ± 0.042	0.0GlnXaa: 0.0 ± 0.0
Arg	2.073ArgAla: 2.073 ± 0.046	0.212ArgCys: 0.212 ± 0.019	1.971ArgAsp: 1.971 ± 0.052	2.801ArgGlu: 2.801 ± 0.053	2.036ArgPhe: 2.036 ± 0.049	2.024ArgGly: 2.024 ± 0.06	0.668ArgHis: 0.668 ± 0.03	3.071ArgIle: 3.071 ± 0.064	3.599ArgLys: 3.599 ± 0.069	3.14ArgLeu: 3.14 ± 0.067	1.127ArgMet: 1.127 ± 0.035	2.583ArgAsn: 2.583 ± 0.068	1.196ArgPro: 1.196 ± 0.041	1.273ArgGln: 1.273 ± 0.044	1.656ArgArg: 1.656 ± 0.055	1.929ArgSer: 1.929 ± 0.051	1.961ArgThr: 1.961 ± 0.049	2.074ArgVal: 2.074 ± 0.045	0.372ArgTrp: 0.372 ± 0.021	1.523ArgTyr: 1.523 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	4.287SerAla: 4.287 ± 0.082	0.609SerCys: 0.609 ± 0.029	3.49SerAsp: 3.49 ± 0.061	4.551SerGlu: 4.551 ± 0.077	3.385SerPhe: 3.385 ± 0.069	4.808SerGly: 4.808 ± 0.094	1.098SerHis: 1.098 ± 0.038	3.941SerIle: 3.941 ± 0.075	4.765SerLys: 4.765 ± 0.081	5.444SerLeu: 5.444 ± 0.083	1.328SerMet: 1.328 ± 0.04	3.18SerAsn: 3.18 ± 0.071	2.122SerPro: 2.122 ± 0.056	2.253SerGln: 2.253 ± 0.054	2.211SerArg: 2.211 ± 0.049	3.779SerSer: 3.779 ± 0.105	3.054SerThr: 3.054 ± 0.069	4.191SerVal: 4.191 ± 0.068	0.615SerTrp: 0.615 ± 0.031	2.514SerTyr: 2.514 ± 0.06	0.0SerXaa: 0.0 ± 0.0
Thr	3.958ThrAla: 3.958 ± 0.079	0.307ThrCys: 0.307 ± 0.02	3.119ThrAsp: 3.119 ± 0.063	3.909ThrGlu: 3.909 ± 0.078	2.732ThrPhe: 2.732 ± 0.061	3.854ThrGly: 3.854 ± 0.072	0.926ThrHis: 0.926 ± 0.034	3.41ThrIle: 3.41 ± 0.062	3.797ThrLys: 3.797 ± 0.07	4.728ThrLeu: 4.728 ± 0.076	1.046ThrMet: 1.046 ± 0.037	2.636ThrAsn: 2.636 ± 0.064	2.162ThrPro: 2.162 ± 0.049	1.769ThrGln: 1.769 ± 0.052	1.654ThrArg: 1.654 ± 0.045	3.18ThrSer: 3.18 ± 0.071	2.745ThrThr: 2.745 ± 0.067	3.922ThrVal: 3.922 ± 0.069	0.473ThrTrp: 0.473 ± 0.024	1.955ThrTyr: 1.955 ± 0.043	0.0ThrXaa: 0.0 ± 0.0
Val	4.168ValAla: 4.168 ± 0.073	0.517ValCys: 0.517 ± 0.025	3.309ValAsp: 3.309 ± 0.068	4.186ValGlu: 4.186 ± 0.081	3.375ValPhe: 3.375 ± 0.068	3.846ValGly: 3.846 ± 0.064	0.941ValHis: 0.941 ± 0.036	4.417ValIle: 4.417 ± 0.073	4.987ValLys: 4.987 ± 0.096	5.689ValLeu: 5.689 ± 0.1	1.613ValMet: 1.613 ± 0.046	3.476ValAsn: 3.476 ± 0.075	2.346ValPro: 2.346 ± 0.06	1.959ValGln: 1.959 ± 0.051	2.173ValArg: 2.173 ± 0.057	4.285ValSer: 4.285 ± 0.076	3.106ValThr: 3.106 ± 0.055	3.949ValVal: 3.949 ± 0.08	0.56ValTrp: 0.56 ± 0.029	2.424ValTyr: 2.424 ± 0.055	0.0ValXaa: 0.0 ± 0.0
Trp	0.617TrpAla: 0.617 ± 0.029	0.065TrpCys: 0.065 ± 0.01	0.63TrpAsp: 0.63 ± 0.027	0.688TrpGlu: 0.688 ± 0.027	0.575TrpPhe: 0.575 ± 0.03	0.622TrpGly: 0.622 ± 0.033	0.169TrpHis: 0.169 ± 0.015	0.714TrpIle: 0.714 ± 0.032	0.876TrpLys: 0.876 ± 0.032	0.968TrpLeu: 0.968 ± 0.04	0.343TrpMet: 0.343 ± 0.018	0.719TrpAsn: 0.719 ± 0.031	0.163TrpPro: 0.163 ± 0.013	0.39TrpGln: 0.39 ± 0.024	0.392TrpArg: 0.392 ± 0.022	0.492TrpSer: 0.492 ± 0.025	0.497TrpThr: 0.497 ± 0.027	0.562TrpVal: 0.562 ± 0.027	0.12TrpTrp: 0.12 ± 0.013	0.407TrpTyr: 0.407 ± 0.024	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.298TyrAla: 2.298 ± 0.059	0.345TyrCys: 0.345 ± 0.024	2.364TyrAsp: 2.364 ± 0.061	2.468TyrGlu: 2.468 ± 0.054	2.625TyrPhe: 2.625 ± 0.068	2.647TyrGly: 2.647 ± 0.057	0.873TyrHis: 0.873 ± 0.032	2.65TyrIle: 2.65 ± 0.06	2.93TyrLys: 2.93 ± 0.069	3.855TyrLeu: 3.855 ± 0.073	0.758TyrMet: 0.758 ± 0.027	2.308TyrAsn: 2.308 ± 0.06	1.459TyrPro: 1.459 ± 0.042	1.644TyrGln: 1.644 ± 0.052	1.796TyrArg: 1.796 ± 0.052	2.73TyrSer: 2.73 ± 0.064	2.027TyrThr: 2.027 ± 0.052	2.03TyrVal: 2.03 ± 0.053	0.469TyrTrp: 0.469 ± 0.026	1.839TyrTyr: 1.839 ± 0.067	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2590 proteins (816362 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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