Amino acid dipepetide frequency for Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383) (Pleurage anserina)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.325AlaAla: 9.325 ± 0.069	0.99AlaCys: 0.99 ± 0.015	3.98AlaAsp: 3.98 ± 0.028	5.164AlaGlu: 5.164 ± 0.042	2.927AlaPhe: 2.927 ± 0.029	6.118AlaGly: 6.118 ± 0.044	1.698AlaHis: 1.698 ± 0.02	3.895AlaIle: 3.895 ± 0.037	4.079AlaLys: 4.079 ± 0.033	7.373AlaLeu: 7.373 ± 0.05	1.925AlaMet: 1.925 ± 0.023	2.855AlaAsn: 2.855 ± 0.025	5.199AlaPro: 5.199 ± 0.05	3.299AlaGln: 3.299 ± 0.032	4.927AlaArg: 4.927 ± 0.036	6.807AlaSer: 6.807 ± 0.043	5.164AlaThr: 5.164 ± 0.037	5.551AlaVal: 5.551 ± 0.039	1.112AlaTrp: 1.112 ± 0.014	1.974AlaTyr: 1.974 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	0.866CysAla: 0.866 ± 0.015	0.278CysCys: 0.278 ± 0.009	0.602CysAsp: 0.602 ± 0.012	0.579CysGlu: 0.579 ± 0.013	0.533CysPhe: 0.533 ± 0.011	0.988CysGly: 0.988 ± 0.019	0.342CysHis: 0.342 ± 0.008	0.625CysIle: 0.625 ± 0.012	0.506CysLys: 0.506 ± 0.01	1.245CysLeu: 1.245 ± 0.019	0.247CysMet: 0.247 ± 0.007	0.428CysAsn: 0.428 ± 0.009	0.722CysPro: 0.722 ± 0.014	0.46CysGln: 0.46 ± 0.011	0.746CysArg: 0.746 ± 0.013	0.902CysSer: 0.902 ± 0.016	0.676CysThr: 0.676 ± 0.013	0.763CysVal: 0.763 ± 0.012	0.231CysTrp: 0.231 ± 0.007	0.344CysTyr: 0.344 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.267AspAla: 4.267 ± 0.031	0.615AspCys: 0.615 ± 0.013	4.238AspAsp: 4.238 ± 0.046	4.46AspGlu: 4.46 ± 0.048	2.121AspPhe: 2.121 ± 0.023	4.184AspGly: 4.184 ± 0.033	1.222AspHis: 1.222 ± 0.015	2.759AspIle: 2.759 ± 0.025	2.503AspLys: 2.503 ± 0.023	4.789AspLeu: 4.789 ± 0.034	1.232AspMet: 1.232 ± 0.018	1.878AspAsn: 1.878 ± 0.024	3.254AspPro: 3.254 ± 0.026	1.774AspGln: 1.774 ± 0.018	3.001AspArg: 3.001 ± 0.033	3.818AspSer: 3.818 ± 0.034	2.74AspThr: 2.74 ± 0.023	3.532AspVal: 3.532 ± 0.028	0.887AspTrp: 0.887 ± 0.014	1.499AspTyr: 1.499 ± 0.021	0.0AspXaa: 0.0 ± 0.0
Glu	5.366GluAla: 5.366 ± 0.046	0.621GluCys: 0.621 ± 0.01	4.233GluAsp: 4.233 ± 0.042	6.528GluGlu: 6.528 ± 0.079	1.965GluPhe: 1.965 ± 0.021	4.505GluGly: 4.505 ± 0.036	1.333GluHis: 1.333 ± 0.016	2.872GluIle: 2.872 ± 0.024	3.965GluLys: 3.965 ± 0.035	5.2GluLeu: 5.2 ± 0.034	1.528GluMet: 1.528 ± 0.019	2.152GluAsn: 2.152 ± 0.019	2.884GluPro: 2.884 ± 0.044	2.541GluGln: 2.541 ± 0.029	4.247GluArg: 4.247 ± 0.043	3.836GluSer: 3.836 ± 0.032	3.448GluThr: 3.448 ± 0.027	3.997GluVal: 3.997 ± 0.036	0.958GluTrp: 0.958 ± 0.014	1.607GluTyr: 1.607 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	2.847PheAla: 2.847 ± 0.026	0.547PheCys: 0.547 ± 0.012	2.195PheAsp: 2.195 ± 0.021	2.121PheGlu: 2.121 ± 0.023	1.585PhePhe: 1.585 ± 0.023	2.913PheGly: 2.913 ± 0.033	0.876PheHis: 0.876 ± 0.013	1.614PheIle: 1.614 ± 0.019	1.498PheLys: 1.498 ± 0.017	3.371PheLeu: 3.371 ± 0.031	0.737PheMet: 0.737 ± 0.012	1.381PheAsn: 1.381 ± 0.017	2.018PhePro: 2.018 ± 0.018	1.33PheGln: 1.33 ± 0.015	1.945PheArg: 1.945 ± 0.022	2.911PheSer: 2.911 ± 0.025	2.139PheThr: 2.139 ± 0.022	2.354PheVal: 2.354 ± 0.027	0.633PheTrp: 0.633 ± 0.012	1.046PheTyr: 1.046 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	5.389GlyAla: 5.389 ± 0.041	0.91GlyCys: 0.91 ± 0.015	3.787GlyAsp: 3.787 ± 0.032	4.359GlyGlu: 4.359 ± 0.038	2.835GlyPhe: 2.835 ± 0.028	7.616GlyGly: 7.616 ± 0.075	1.744GlyHis: 1.744 ± 0.023	3.299GlyIle: 3.299 ± 0.031	3.759GlyLys: 3.759 ± 0.029	6.283GlyLeu: 6.283 ± 0.043	1.696GlyMet: 1.696 ± 0.019	2.686GlyAsn: 2.686 ± 0.03	3.618GlyPro: 3.618 ± 0.032	2.724GlyGln: 2.724 ± 0.028	4.561GlyArg: 4.561 ± 0.04	5.762GlySer: 5.762 ± 0.041	4.052GlyThr: 4.052 ± 0.039	4.904GlyVal: 4.904 ± 0.034	1.304GlyTrp: 1.304 ± 0.017	2.193GlyTyr: 2.193 ± 0.026	0.0GlyXaa: 0.0 ± 0.0
His	1.696HisAla: 1.696 ± 0.022	0.332HisCys: 0.332 ± 0.01	1.269HisAsp: 1.269 ± 0.017	1.252HisGlu: 1.252 ± 0.015	0.892HisPhe: 0.892 ± 0.013	1.701HisGly: 1.701 ± 0.022	1.125HisHis: 1.125 ± 0.02	1.157HisIle: 1.157 ± 0.014	0.931HisLys: 0.931 ± 0.013	2.217HisLeu: 2.217 ± 0.021	0.473HisMet: 0.473 ± 0.011	0.864HisAsn: 0.864 ± 0.014	1.804HisPro: 1.804 ± 0.024	1.14HisGln: 1.14 ± 0.018	1.547HisArg: 1.547 ± 0.02	1.804HisSer: 1.804 ± 0.022	1.248HisThr: 1.248 ± 0.015	1.386HisVal: 1.386 ± 0.019	0.324HisTrp: 0.324 ± 0.007	0.684HisTyr: 0.684 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	3.728IleAla: 3.728 ± 0.032	0.656IleCys: 0.656 ± 0.012	2.543IleAsp: 2.543 ± 0.022	2.609IleGlu: 2.609 ± 0.021	1.769IlePhe: 1.769 ± 0.019	2.907IleGly: 2.907 ± 0.025	1.114IleHis: 1.114 ± 0.016	2.264IleIle: 2.264 ± 0.027	2.252IleLys: 2.252 ± 0.022	4.201IleLeu: 4.201 ± 0.034	0.959IleMet: 0.959 ± 0.015	1.729IleAsn: 1.729 ± 0.021	3.058IlePro: 3.058 ± 0.027	1.683IleGln: 1.683 ± 0.019	2.629IleArg: 2.629 ± 0.024	3.545IleSer: 3.545 ± 0.026	2.926IleThr: 2.926 ± 0.025	2.889IleVal: 2.889 ± 0.029	0.714IleTrp: 0.714 ± 0.013	1.29IleTyr: 1.29 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	4.283LysAla: 4.283 ± 0.034	0.491LysCys: 0.491 ± 0.011	2.676LysAsp: 2.676 ± 0.027	3.72LysGlu: 3.72 ± 0.038	1.472LysPhe: 1.472 ± 0.016	3.352LysGly: 3.352 ± 0.03	1.106LysHis: 1.106 ± 0.015	2.255LysIle: 2.255 ± 0.023	3.751LysLys: 3.751 ± 0.051	4.107LysLeu: 4.107 ± 0.026	1.092LysMet: 1.092 ± 0.017	1.684LysAsn: 1.684 ± 0.02	2.926LysPro: 2.926 ± 0.034	1.88LysGln: 1.88 ± 0.022	3.513LysArg: 3.513 ± 0.033	3.27LysSer: 3.27 ± 0.03	2.943LysThr: 2.943 ± 0.024	2.969LysVal: 2.969 ± 0.026	0.722LysTrp: 0.722 ± 0.012	1.293LysTyr: 1.293 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	7.776LeuAla: 7.776 ± 0.048	1.145LeuCys: 1.145 ± 0.016	4.89LeuAsp: 4.89 ± 0.033	5.54LeuGlu: 5.54 ± 0.041	3.264LeuPhe: 3.264 ± 0.032	6.132LeuGly: 6.132 ± 0.036	2.11LeuHis: 2.11 ± 0.021	3.643LeuIle: 3.643 ± 0.034	4.143LeuLys: 4.143 ± 0.032	8.269LeuLeu: 8.269 ± 0.061	1.746LeuMet: 1.746 ± 0.021	2.962LeuAsn: 2.962 ± 0.025	5.838LeuPro: 5.838 ± 0.044	3.534LeuGln: 3.534 ± 0.031	5.613LeuArg: 5.613 ± 0.037	7.132LeuSer: 7.132 ± 0.045	5.039LeuThr: 5.039 ± 0.032	5.453LeuVal: 5.453 ± 0.038	1.211LeuTrp: 1.211 ± 0.016	2.16LeuTyr: 2.16 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	2.222MetAla: 2.222 ± 0.021	0.234MetCys: 0.234 ± 0.008	1.201MetAsp: 1.201 ± 0.016	1.349MetGlu: 1.349 ± 0.019	0.716MetPhe: 0.716 ± 0.012	1.63MetGly: 1.63 ± 0.018	0.44MetHis: 0.44 ± 0.009	0.907MetIle: 0.907 ± 0.013	0.998MetLys: 0.998 ± 0.013	1.768MetLeu: 1.768 ± 0.017	0.633MetMet: 0.633 ± 0.012	0.735MetAsn: 0.735 ± 0.014	1.245MetPro: 1.245 ± 0.018	0.766MetGln: 0.766 ± 0.017	1.279MetArg: 1.279 ± 0.015	1.8MetSer: 1.8 ± 0.017	1.292MetThr: 1.292 ± 0.017	1.388MetVal: 1.388 ± 0.017	0.266MetTrp: 0.266 ± 0.007	0.503MetTyr: 0.503 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.795AsnAla: 2.795 ± 0.025	0.442AsnCys: 0.442 ± 0.01	1.851AsnAsp: 1.851 ± 0.019	1.859AsnGlu: 1.859 ± 0.02	1.331AsnPhe: 1.331 ± 0.017	3.011AsnGly: 3.011 ± 0.032	0.87AsnHis: 0.87 ± 0.013	1.893AsnIle: 1.893 ± 0.021	1.692AsnLys: 1.692 ± 0.017	3.158AsnLeu: 3.158 ± 0.024	0.821AsnMet: 0.821 ± 0.011	1.845AsnAsn: 1.845 ± 0.037	2.586AsnPro: 2.586 ± 0.026	1.299AsnGln: 1.299 ± 0.018	1.974AsnArg: 1.974 ± 0.022	2.634AsnSer: 2.634 ± 0.026	2.233AsnThr: 2.233 ± 0.022	2.106AsnVal: 2.106 ± 0.019	0.571AsnTrp: 0.571 ± 0.011	1.01AsnTyr: 1.01 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	5.798ProAla: 5.798 ± 0.05	0.561ProCys: 0.561 ± 0.013	3.238ProAsp: 3.238 ± 0.03	3.989ProGlu: 3.989 ± 0.039	2.091ProPhe: 2.091 ± 0.02	4.405ProGly: 4.405 ± 0.038	1.409ProHis: 1.409 ± 0.018	2.541ProIle: 2.541 ± 0.023	2.852ProLys: 2.852 ± 0.032	4.988ProLeu: 4.988 ± 0.037	1.059ProMet: 1.059 ± 0.018	2.31ProAsn: 2.31 ± 0.026	6.693ProPro: 6.693 ± 0.08	2.634ProGln: 2.634 ± 0.034	3.627ProArg: 3.627 ± 0.035	6.359ProSer: 6.359 ± 0.05	4.471ProThr: 4.471 ± 0.04	4.033ProVal: 4.033 ± 0.04	0.749ProTrp: 0.749 ± 0.012	1.48ProTyr: 1.48 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.439GlnAla: 3.439 ± 0.033	0.418GlnCys: 0.418 ± 0.009	1.969GlnAsp: 1.969 ± 0.019	2.459GlnGlu: 2.459 ± 0.028	1.263GlnPhe: 1.263 ± 0.015	2.526GlnGly: 2.526 ± 0.029	1.184GlnHis: 1.184 ± 0.02	1.745GlnIle: 1.745 ± 0.02	1.927GlnLys: 1.927 ± 0.021	3.362GlnLeu: 3.362 ± 0.029	0.825GlnMet: 0.825 ± 0.015	1.438GlnAsn: 1.438 ± 0.018	2.833GlnPro: 2.833 ± 0.032	3.24GlnGln: 3.24 ± 0.077	2.561GlnArg: 2.561 ± 0.025	2.824GlnSer: 2.824 ± 0.026	2.305GlnThr: 2.305 ± 0.021	2.211GlnVal: 2.211 ± 0.023	0.543GlnTrp: 0.543 ± 0.009	1.088GlnTyr: 1.088 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	4.671ArgAla: 4.671 ± 0.037	0.73ArgCys: 0.73 ± 0.011	3.338ArgAsp: 3.338 ± 0.036	4.173ArgGlu: 4.173 ± 0.037	2.127ArgPhe: 2.127 ± 0.021	4.233ArgGly: 4.233 ± 0.031	1.608ArgHis: 1.608 ± 0.021	2.697ArgIle: 2.697 ± 0.024	3.415ArgLys: 3.415 ± 0.029	5.433ArgLeu: 5.433 ± 0.037	1.345ArgMet: 1.345 ± 0.015	2.185ArgAsn: 2.185 ± 0.021	3.784ArgPro: 3.784 ± 0.034	2.724ArgGln: 2.724 ± 0.026	5.255ArgArg: 5.255 ± 0.058	4.649ArgSer: 4.649 ± 0.045	3.254ArgThr: 3.254 ± 0.027	3.578ArgVal: 3.578 ± 0.027	0.97ArgTrp: 0.97 ± 0.013	1.665ArgTyr: 1.665 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	6.179SerAla: 6.179 ± 0.039	0.899SerCys: 0.899 ± 0.013	3.851SerAsp: 3.851 ± 0.034	3.819SerGlu: 3.819 ± 0.027	2.935SerPhe: 2.935 ± 0.026	5.525SerGly: 5.525 ± 0.046	1.947SerHis: 1.947 ± 0.02	3.482SerIle: 3.482 ± 0.027	3.489SerLys: 3.489 ± 0.027	7.11SerLeu: 7.11 ± 0.039	1.572SerMet: 1.572 ± 0.021	2.841SerAsn: 2.841 ± 0.024	6.057SerPro: 6.057 ± 0.056	3.147SerGln: 3.147 ± 0.03	4.93SerArg: 4.93 ± 0.046	8.746SerSer: 8.746 ± 0.081	5.594SerThr: 5.594 ± 0.095	4.453SerVal: 4.453 ± 0.033	1.119SerTrp: 1.119 ± 0.014	1.93SerTyr: 1.93 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.367ThrAla: 5.367 ± 0.04	0.767ThrCys: 0.767 ± 0.014	2.727ThrAsp: 2.727 ± 0.025	3.117ThrGlu: 3.117 ± 0.027	2.124ThrPhe: 2.124 ± 0.023	4.295ThrGly: 4.295 ± 0.041	1.289ThrHis: 1.289 ± 0.016	2.982ThrIle: 2.982 ± 0.028	2.707ThrLys: 2.707 ± 0.029	5.188ThrLeu: 5.188 ± 0.034	1.145ThrMet: 1.145 ± 0.017	2.131ThrAsn: 2.131 ± 0.023	4.865ThrPro: 4.865 ± 0.041	2.055ThrGln: 2.055 ± 0.019	3.251ThrArg: 3.251 ± 0.027	5.397ThrSer: 5.397 ± 0.108	5.256ThrThr: 5.256 ± 0.164	3.86ThrVal: 3.86 ± 0.031	0.839ThrTrp: 0.839 ± 0.014	1.491ThrTyr: 1.491 ± 0.021	0.0ThrXaa: 0.0 ± 0.0
Val	5.267ValAla: 5.267 ± 0.042	0.844ValCys: 0.844 ± 0.014	3.693ValAsp: 3.693 ± 0.031	4.241ValGlu: 4.241 ± 0.037	2.424ValPhe: 2.424 ± 0.023	4.37ValGly: 4.37 ± 0.032	1.335ValHis: 1.335 ± 0.017	2.89ValIle: 2.89 ± 0.025	3.109ValLys: 3.109 ± 0.029	5.601ValLeu: 5.601 ± 0.037	1.404ValMet: 1.404 ± 0.016	2.187ValAsn: 2.187 ± 0.022	3.793ValPro: 3.793 ± 0.034	2.313ValGln: 2.313 ± 0.023	3.662ValArg: 3.662 ± 0.028	4.532ValSer: 4.532 ± 0.028	3.636ValThr: 3.636 ± 0.033	4.863ValVal: 4.863 ± 0.035	0.93ValTrp: 0.93 ± 0.015	1.718ValTyr: 1.718 ± 0.017	0.0ValXaa: 0.0 ± 0.0
Trp	1.136TrpAla: 1.136 ± 0.015	0.208TrpCys: 0.208 ± 0.006	0.928TrpAsp: 0.928 ± 0.015	0.968TrpGlu: 0.968 ± 0.015	0.567TrpPhe: 0.567 ± 0.01	1.054TrpGly: 1.054 ± 0.016	0.339TrpHis: 0.339 ± 0.009	0.692TrpIle: 0.692 ± 0.014	0.82TrpLys: 0.82 ± 0.012	1.35TrpLeu: 1.35 ± 0.017	0.377TrpMet: 0.377 ± 0.01	0.614TrpAsn: 0.614 ± 0.011	0.623TrpPro: 0.623 ± 0.015	0.537TrpGln: 0.537 ± 0.01	0.983TrpArg: 0.983 ± 0.015	1.023TrpSer: 1.023 ± 0.014	0.895TrpThr: 0.895 ± 0.012	0.985TrpVal: 0.985 ± 0.014	0.295TrpTrp: 0.295 ± 0.008	0.423TrpTyr: 0.423 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.946TyrAla: 1.946 ± 0.019	0.397TyrCys: 0.397 ± 0.011	1.561TyrAsp: 1.561 ± 0.02	1.482TyrGlu: 1.482 ± 0.018	1.12TyrPhe: 1.12 ± 0.014	2.018TyrGly: 2.018 ± 0.024	0.755TyrHis: 0.755 ± 0.013	1.251TyrIle: 1.251 ± 0.016	1.109TyrLys: 1.109 ± 0.016	2.586TyrLeu: 2.586 ± 0.029	0.555TyrMet: 0.555 ± 0.01	1.074TyrAsn: 1.074 ± 0.015	1.485TyrPro: 1.485 ± 0.02	1.081TyrGln: 1.081 ± 0.015	1.583TyrArg: 1.583 ± 0.02	1.876TyrSer: 1.876 ± 0.022	1.545TyrThr: 1.545 ± 0.019	1.538TyrVal: 1.538 ± 0.016	0.439TyrTrp: 0.439 ± 0.01	0.897TyrTyr: 0.897 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 10657 proteins (5371942 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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