Amino acid dipepetide frequency for Corynebacterium mustelae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.153AlaAla: 14.153 ± 0.169	1.017AlaCys: 1.017 ± 0.033	6.248AlaAsp: 6.248 ± 0.085	7.446AlaGlu: 7.446 ± 0.109	3.344AlaPhe: 3.344 ± 0.062	8.597AlaGly: 8.597 ± 0.099	2.474AlaHis: 2.474 ± 0.056	6.256AlaIle: 6.256 ± 0.083	4.172AlaLys: 4.172 ± 0.085	10.524AlaLeu: 10.524 ± 0.129	2.37AlaMet: 2.37 ± 0.048	2.896AlaAsn: 2.896 ± 0.056	4.496AlaPro: 4.496 ± 0.088	4.447AlaGln: 4.447 ± 0.07	5.878AlaArg: 5.878 ± 0.078	5.426AlaSer: 5.426 ± 0.077	7.306AlaThr: 7.306 ± 0.091	8.957AlaVal: 8.957 ± 0.115	1.488AlaTrp: 1.488 ± 0.04	2.179AlaTyr: 2.179 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	1.079CysAla: 1.079 ± 0.039	0.135CysCys: 0.135 ± 0.014	0.613CysAsp: 0.613 ± 0.028	0.558CysGlu: 0.558 ± 0.024	0.39CysPhe: 0.39 ± 0.018	0.93CysGly: 0.93 ± 0.033	0.236CysHis: 0.236 ± 0.016	0.455CysIle: 0.455 ± 0.022	0.206CysLys: 0.206 ± 0.016	0.743CysLeu: 0.743 ± 0.028	0.176CysMet: 0.176 ± 0.013	0.254CysAsn: 0.254 ± 0.018	0.447CysPro: 0.447 ± 0.022	0.271CysGln: 0.271 ± 0.015	0.464CysArg: 0.464 ± 0.022	0.57CysSer: 0.57 ± 0.023	0.644CysThr: 0.644 ± 0.027	0.778CysVal: 0.778 ± 0.028	0.153CysTrp: 0.153 ± 0.013	0.223CysTyr: 0.223 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	6.073AspAla: 6.073 ± 0.079	0.567AspCys: 0.567 ± 0.026	3.463AspAsp: 3.463 ± 0.072	3.78AspGlu: 3.78 ± 0.078	2.55AspPhe: 2.55 ± 0.054	4.441AspGly: 4.441 ± 0.074	1.26AspHis: 1.26 ± 0.038	3.449AspIle: 3.449 ± 0.063	1.921AspLys: 1.921 ± 0.05	5.141AspLeu: 5.141 ± 0.071	1.186AspMet: 1.186 ± 0.031	1.92AspAsn: 1.92 ± 0.047	3.479AspPro: 3.479 ± 0.058	1.737AspGln: 1.737 ± 0.039	3.085AspArg: 3.085 ± 0.052	3.544AspSer: 3.544 ± 0.065	3.334AspThr: 3.334 ± 0.053	4.642AspVal: 4.642 ± 0.075	0.861AspTrp: 0.861 ± 0.033	1.646AspTyr: 1.646 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	5.931GluAla: 5.931 ± 0.082	0.527GluCys: 0.527 ± 0.027	2.866GluAsp: 2.866 ± 0.064	3.842GluGlu: 3.842 ± 0.084	2.343GluPhe: 2.343 ± 0.048	3.194GluGly: 3.194 ± 0.062	1.482GluHis: 1.482 ± 0.046	3.958GluIle: 3.958 ± 0.062	3.099GluLys: 3.099 ± 0.064	6.911GluLeu: 6.911 ± 0.103	1.214GluMet: 1.214 ± 0.038	2.327GluAsn: 2.327 ± 0.051	2.723GluPro: 2.723 ± 0.06	2.542GluGln: 2.542 ± 0.052	3.282GluArg: 3.282 ± 0.064	3.491GluSer: 3.491 ± 0.059	3.772GluThr: 3.772 ± 0.051	4.539GluVal: 4.539 ± 0.078	0.836GluTrp: 0.836 ± 0.028	1.541GluTyr: 1.541 ± 0.042	0.0GluXaa: 0.0 ± 0.0
Phe	4.047PheAla: 4.047 ± 0.073	0.388PheCys: 0.388 ± 0.02	2.656PheAsp: 2.656 ± 0.061	1.904PheGlu: 1.904 ± 0.042	1.549PhePhe: 1.549 ± 0.048	3.373PheGly: 3.373 ± 0.072	0.857PheHis: 0.857 ± 0.034	2.009PheIle: 2.009 ± 0.048	1.003PheLys: 1.003 ± 0.031	3.285PheLeu: 3.285 ± 0.066	0.67PheMet: 0.67 ± 0.032	1.274PheAsn: 1.274 ± 0.035	1.762PhePro: 1.762 ± 0.042	1.015PheGln: 1.015 ± 0.03	1.86PheArg: 1.86 ± 0.039	2.776PheSer: 2.776 ± 0.06	2.258PheThr: 2.258 ± 0.052	2.726PheVal: 2.726 ± 0.053	0.447PheTrp: 0.447 ± 0.022	0.909PheTyr: 0.909 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	7.338GlyAla: 7.338 ± 0.103	0.807GlyCys: 0.807 ± 0.028	4.227GlyAsp: 4.227 ± 0.064	4.464GlyGlu: 4.464 ± 0.078	3.323GlyPhe: 3.323 ± 0.065	5.942GlyGly: 5.942 ± 0.113	1.714GlyHis: 1.714 ± 0.044	4.882GlyIle: 4.882 ± 0.074	3.119GlyLys: 3.119 ± 0.057	7.282GlyLeu: 7.282 ± 0.108	1.996GlyMet: 1.996 ± 0.049	2.452GlyAsn: 2.452 ± 0.053	2.619GlyPro: 2.619 ± 0.055	2.452GlyGln: 2.452 ± 0.048	3.989GlyArg: 3.989 ± 0.074	4.568GlySer: 4.568 ± 0.065	4.95GlyThr: 4.95 ± 0.075	6.449GlyVal: 6.449 ± 0.084	1.381GlyTrp: 1.381 ± 0.043	2.121GlyTyr: 2.121 ± 0.043	0.0GlyXaa: 0.0 ± 0.0
His	2.275HisAla: 2.275 ± 0.057	0.245HisCys: 0.245 ± 0.017	1.435HisAsp: 1.435 ± 0.041	1.245HisGlu: 1.245 ± 0.036	0.779HisPhe: 0.779 ± 0.025	1.742HisGly: 1.742 ± 0.041	0.706HisHis: 0.706 ± 0.03	1.312HisIle: 1.312 ± 0.035	0.629HisLys: 0.629 ± 0.025	2.093HisLeu: 2.093 ± 0.05	0.484HisMet: 0.484 ± 0.023	0.87HisAsn: 0.87 ± 0.032	1.495HisPro: 1.495 ± 0.041	0.846HisGln: 0.846 ± 0.032	1.502HisArg: 1.502 ± 0.041	1.399HisSer: 1.399 ± 0.043	1.466HisThr: 1.466 ± 0.041	1.672HisVal: 1.672 ± 0.041	0.321HisTrp: 0.321 ± 0.018	0.653HisTyr: 0.653 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	7.481IleAla: 7.481 ± 0.076	0.532IleCys: 0.532 ± 0.025	4.108IleAsp: 4.108 ± 0.069	3.325IleGlu: 3.325 ± 0.064	1.895IlePhe: 1.895 ± 0.055	4.753IleGly: 4.753 ± 0.082	1.175IleHis: 1.175 ± 0.038	3.219IleIle: 3.219 ± 0.073	1.721IleLys: 1.721 ± 0.047	4.362IleLeu: 4.362 ± 0.073	1.044IleMet: 1.044 ± 0.032	1.904IleAsn: 1.904 ± 0.048	3.22IlePro: 3.22 ± 0.056	1.473IleGln: 1.473 ± 0.04	3.042IleArg: 3.042 ± 0.062	3.744IleSer: 3.744 ± 0.068	4.282IleThr: 4.282 ± 0.083	4.538IleVal: 4.538 ± 0.09	0.548IleTrp: 0.548 ± 0.026	1.072IleTyr: 1.072 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	3.714LysAla: 3.714 ± 0.066	0.202LysCys: 0.202 ± 0.014	1.953LysAsp: 1.953 ± 0.054	2.228LysGlu: 2.228 ± 0.053	1.085LysPhe: 1.085 ± 0.038	2.063LysGly: 2.063 ± 0.053	0.813LysHis: 0.813 ± 0.026	2.043LysIle: 2.043 ± 0.05	1.969LysLys: 1.969 ± 0.058	3.615LysLeu: 3.615 ± 0.067	0.766LysMet: 0.766 ± 0.026	1.506LysAsn: 1.506 ± 0.041	2.126LysPro: 2.126 ± 0.053	1.425LysGln: 1.425 ± 0.041	2.133LysArg: 2.133 ± 0.046	1.902LysSer: 1.902 ± 0.047	2.491LysThr: 2.491 ± 0.057	2.675LysVal: 2.675 ± 0.061	0.521LysTrp: 0.521 ± 0.022	0.815LysTyr: 0.815 ± 0.033	0.0LysXaa: 0.0 ± 0.0
Leu	11.155LeuAla: 11.155 ± 0.137	0.981LeuCys: 0.981 ± 0.033	5.471LeuAsp: 5.471 ± 0.089	5.013LeuGlu: 5.013 ± 0.079	3.19LeuPhe: 3.19 ± 0.067	7.685LeuGly: 7.685 ± 0.096	2.045LeuHis: 2.045 ± 0.048	5.299LeuIle: 5.299 ± 0.092	3.294LeuLys: 3.294 ± 0.057	8.559LeuLeu: 8.559 ± 0.109	1.861LeuMet: 1.861 ± 0.045	2.91LeuAsn: 2.91 ± 0.054	5.194LeuPro: 5.194 ± 0.079	2.731LeuGln: 2.731 ± 0.065	5.917LeuArg: 5.917 ± 0.087	6.713LeuSer: 6.713 ± 0.088	5.709LeuThr: 5.709 ± 0.066	7.474LeuVal: 7.474 ± 0.1	1.355LeuTrp: 1.355 ± 0.04	2.021LeuTyr: 2.021 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	2.342MetAla: 2.342 ± 0.055	0.205MetCys: 0.205 ± 0.013	0.993MetAsp: 0.993 ± 0.037	1.026MetGlu: 1.026 ± 0.035	0.719MetPhe: 0.719 ± 0.028	1.492MetGly: 1.492 ± 0.045	0.431MetHis: 0.431 ± 0.021	1.151MetIle: 1.151 ± 0.037	0.834MetLys: 0.834 ± 0.03	2.073MetLeu: 2.073 ± 0.052	0.461MetMet: 0.461 ± 0.023	0.732MetAsn: 0.732 ± 0.025	1.116MetPro: 1.116 ± 0.033	0.639MetGln: 0.639 ± 0.023	1.354MetArg: 1.354 ± 0.037	1.556MetSer: 1.556 ± 0.04	1.464MetThr: 1.464 ± 0.038	1.74MetVal: 1.74 ± 0.04	0.37MetTrp: 0.37 ± 0.022	0.406MetTyr: 0.406 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	3.232AsnAla: 3.232 ± 0.058	0.275AsnCys: 0.275 ± 0.014	1.637AsnAsp: 1.637 ± 0.043	1.617AsnGlu: 1.617 ± 0.039	1.187AsnPhe: 1.187 ± 0.031	2.4AsnGly: 2.4 ± 0.046	0.821AsnHis: 0.821 ± 0.029	1.662AsnIle: 1.662 ± 0.044	1.104AsnLys: 1.104 ± 0.031	2.978AsnLeu: 2.978 ± 0.06	0.638AsnMet: 0.638 ± 0.027	1.123AsnAsn: 1.123 ± 0.042	2.586AsnPro: 2.586 ± 0.056	1.268AsnGln: 1.268 ± 0.038	1.923AsnArg: 1.923 ± 0.048	1.874AsnSer: 1.874 ± 0.047	1.851AsnThr: 1.851 ± 0.049	2.2AsnVal: 2.2 ± 0.046	0.464AsnTrp: 0.464 ± 0.022	0.882AsnTyr: 0.882 ± 0.03	0.0AsnXaa: 0.0 ± 0.0
Pro	5.372ProAla: 5.372 ± 0.099	0.327ProCys: 0.327 ± 0.019	3.243ProAsp: 3.243 ± 0.059	4.137ProGlu: 4.137 ± 0.083	1.587ProPhe: 1.587 ± 0.042	4.132ProGly: 4.132 ± 0.07	1.437ProHis: 1.437 ± 0.036	2.551ProIle: 2.551 ± 0.047	1.901ProLys: 1.901 ± 0.047	4.357ProLeu: 4.357 ± 0.075	1.005ProMet: 1.005 ± 0.031	1.625ProAsn: 1.625 ± 0.038	2.225ProPro: 2.225 ± 0.068	2.087ProGln: 2.087 ± 0.054	2.519ProArg: 2.519 ± 0.056	2.817ProSer: 2.817 ± 0.053	3.692ProThr: 3.692 ± 0.067	4.258ProVal: 4.258 ± 0.066	0.691ProTrp: 0.691 ± 0.028	1.114ProTyr: 1.114 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	3.848GlnAla: 3.848 ± 0.059	0.296GlnCys: 0.296 ± 0.019	1.406GlnAsp: 1.406 ± 0.039	1.998GlnGlu: 1.998 ± 0.055	1.191GlnPhe: 1.191 ± 0.038	1.934GlnGly: 1.934 ± 0.048	0.866GlnHis: 0.866 ± 0.031	1.861GlnIle: 1.861 ± 0.043	1.205GlnLys: 1.205 ± 0.04	4.333GlnLeu: 4.333 ± 0.07	0.714GlnMet: 0.714 ± 0.029	0.828GlnAsn: 0.828 ± 0.031	2.272GlnPro: 2.272 ± 0.059	1.793GlnGln: 1.793 ± 0.059	2.441GlnArg: 2.441 ± 0.059	1.916GlnSer: 1.916 ± 0.049	1.659GlnThr: 1.659 ± 0.043	2.584GlnVal: 2.584 ± 0.054	0.699GlnTrp: 0.699 ± 0.028	0.757GlnTyr: 0.757 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	5.211ArgAla: 5.211 ± 0.07	0.495ArgCys: 0.495 ± 0.023	3.217ArgAsp: 3.217 ± 0.064	3.433ArgGlu: 3.433 ± 0.067	2.3ArgPhe: 2.3 ± 0.054	3.733ArgGly: 3.733 ± 0.067	1.37ArgHis: 1.37 ± 0.039	3.534ArgIle: 3.534 ± 0.065	2.334ArgLys: 2.334 ± 0.046	5.527ArgLeu: 5.527 ± 0.085	1.48ArgMet: 1.48 ± 0.037	2.048ArgAsn: 2.048 ± 0.045	2.494ArgPro: 2.494 ± 0.054	2.005ArgGln: 2.005 ± 0.042	4.216ArgArg: 4.216 ± 0.08	3.358ArgSer: 3.358 ± 0.059	3.296ArgThr: 3.296 ± 0.06	4.051ArgVal: 4.051 ± 0.078	0.963ArgTrp: 0.963 ± 0.034	1.62ArgTyr: 1.62 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	6.417SerAla: 6.417 ± 0.073	0.542SerCys: 0.542 ± 0.024	3.546SerAsp: 3.546 ± 0.067	3.502SerGlu: 3.502 ± 0.065	2.431SerPhe: 2.431 ± 0.054	5.621SerGly: 5.621 ± 0.088	1.457SerHis: 1.457 ± 0.034	3.197SerIle: 3.197 ± 0.061	1.91SerLys: 1.91 ± 0.046	5.427SerLeu: 5.427 ± 0.074	1.429SerMet: 1.429 ± 0.037	1.722SerAsn: 1.722 ± 0.038	3.103SerPro: 3.103 ± 0.048	2.131SerGln: 2.131 ± 0.04	3.339SerArg: 3.339 ± 0.064	3.878SerSer: 3.878 ± 0.084	3.994SerThr: 3.994 ± 0.064	4.794SerVal: 4.794 ± 0.062	0.942SerTrp: 0.942 ± 0.027	1.484SerTyr: 1.484 ± 0.042	0.0SerXaa: 0.0 ± 0.0
Thr	6.951ThrAla: 6.951 ± 0.083	0.561ThrCys: 0.561 ± 0.03	3.733ThrAsp: 3.733 ± 0.065	3.69ThrGlu: 3.69 ± 0.071	2.241ThrPhe: 2.241 ± 0.049	5.135ThrGly: 5.135 ± 0.072	1.527ThrHis: 1.527 ± 0.041	3.955ThrIle: 3.955 ± 0.067	2.154ThrLys: 2.154 ± 0.049	5.703ThrLeu: 5.703 ± 0.076	1.281ThrMet: 1.281 ± 0.039	2.04ThrAsn: 2.04 ± 0.044	3.915ThrPro: 3.915 ± 0.065	2.118ThrGln: 2.118 ± 0.055	3.062ThrArg: 3.062 ± 0.059	3.647ThrSer: 3.647 ± 0.058	4.691ThrThr: 4.691 ± 0.086	5.45ThrVal: 5.45 ± 0.078	0.931ThrTrp: 0.931 ± 0.029	1.441ThrTyr: 1.441 ± 0.046	0.0ThrXaa: 0.0 ± 0.0
Val	9.385ValAla: 9.385 ± 0.107	0.786ValCys: 0.786 ± 0.027	5.003ValAsp: 5.003 ± 0.077	4.96ValGlu: 4.96 ± 0.081	3.006ValPhe: 3.006 ± 0.063	5.949ValGly: 5.949 ± 0.109	1.57ValHis: 1.57 ± 0.041	4.802ValIle: 4.802 ± 0.081	2.362ValLys: 2.362 ± 0.053	7.443ValLeu: 7.443 ± 0.101	1.653ValMet: 1.653 ± 0.044	2.021ValAsn: 2.021 ± 0.04	3.834ValPro: 3.834 ± 0.056	2.006ValGln: 2.006 ± 0.048	4.157ValArg: 4.157 ± 0.076	5.262ValSer: 5.262 ± 0.078	5.47ValThr: 5.47 ± 0.087	7.456ValVal: 7.456 ± 0.123	1.093ValTrp: 1.093 ± 0.032	1.701ValTyr: 1.701 ± 0.049	0.0ValXaa: 0.0 ± 0.0
Trp	1.408TrpAla: 1.408 ± 0.041	0.185TrpCys: 0.185 ± 0.014	0.857TrpAsp: 0.857 ± 0.029	0.898TrpGlu: 0.898 ± 0.031	0.611TrpPhe: 0.611 ± 0.024	0.951TrpGly: 0.951 ± 0.033	0.366TrpHis: 0.366 ± 0.019	0.738TrpIle: 0.738 ± 0.029	0.49TrpLys: 0.49 ± 0.024	1.757TrpLeu: 1.757 ± 0.045	0.296TrpMet: 0.296 ± 0.019	0.498TrpAsn: 0.498 ± 0.022	0.689TrpPro: 0.689 ± 0.03	0.682TrpGln: 0.682 ± 0.025	0.983TrpArg: 0.983 ± 0.033	0.819TrpSer: 0.819 ± 0.029	0.615TrpThr: 0.615 ± 0.026	1.229TrpVal: 1.229 ± 0.044	0.343TrpTrp: 0.343 ± 0.02	0.325TrpTyr: 0.325 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.26TyrAla: 2.26 ± 0.043	0.254TyrCys: 0.254 ± 0.017	1.405TyrAsp: 1.405 ± 0.04	1.357TyrGlu: 1.357 ± 0.035	1.046TyrPhe: 1.046 ± 0.032	2.011TyrGly: 2.011 ± 0.049	0.561TyrHis: 0.561 ± 0.024	1.104TyrIle: 1.104 ± 0.032	0.617TyrLys: 0.617 ± 0.025	2.466TyrLeu: 2.466 ± 0.056	0.379TyrMet: 0.379 ± 0.021	0.773TyrAsn: 0.773 ± 0.029	1.277TyrPro: 1.277 ± 0.04	0.934TyrGln: 0.934 ± 0.03	1.538TyrArg: 1.538 ± 0.041	1.606TyrSer: 1.606 ± 0.04	1.28TyrThr: 1.28 ± 0.046	1.707TyrVal: 1.707 ± 0.043	0.333TyrTrp: 0.333 ± 0.018	0.583TyrTyr: 0.583 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3046 proteins (1001453 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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