Amino acid dipepetide frequency for Phellinidium pouzarii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.471AlaAla: 8.471 ± 0.063	1.038AlaCys: 1.038 ± 0.016	4.431AlaAsp: 4.431 ± 0.033	4.891AlaGlu: 4.891 ± 0.038	3.389AlaPhe: 3.389 ± 0.028	5.143AlaGly: 5.143 ± 0.046	2.178AlaHis: 2.178 ± 0.024	4.053AlaIle: 4.053 ± 0.031	3.724AlaLys: 3.724 ± 0.03	8.576AlaLeu: 8.576 ± 0.054	1.761AlaMet: 1.761 ± 0.022	3.029AlaAsn: 3.029 ± 0.029	4.918AlaPro: 4.918 ± 0.045	3.294AlaGln: 3.294 ± 0.027	5.404AlaArg: 5.404 ± 0.036	8.147AlaSer: 8.147 ± 0.057	4.902AlaThr: 4.902 ± 0.038	5.247AlaVal: 5.247 ± 0.039	1.04AlaTrp: 1.04 ± 0.016	2.244AlaTyr: 2.244 ± 0.025	0.028AlaXaa: 0.028 ± 0.002
Cys	0.95CysAla: 0.95 ± 0.017	0.215CysCys: 0.215 ± 0.008	0.639CysAsp: 0.639 ± 0.013	0.597CysGlu: 0.597 ± 0.012	0.503CysPhe: 0.503 ± 0.01	0.829CysGly: 0.829 ± 0.015	0.275CysHis: 0.275 ± 0.008	0.682CysIle: 0.682 ± 0.013	0.498CysLys: 0.498 ± 0.012	1.166CysLeu: 1.166 ± 0.017	0.257CysMet: 0.257 ± 0.008	0.473CysAsn: 0.473 ± 0.01	0.662CysPro: 0.662 ± 0.011	0.41CysGln: 0.41 ± 0.009	0.706CysArg: 0.706 ± 0.014	0.928CysSer: 0.928 ± 0.013	0.725CysThr: 0.725 ± 0.014	0.77CysVal: 0.77 ± 0.014	0.151CysTrp: 0.151 ± 0.006	0.298CysTyr: 0.298 ± 0.009	0.004CysXaa: 0.004 ± 0.001
Asp	5.253AspAla: 5.253 ± 0.037	0.619AspCys: 0.619 ± 0.011	4.335AspAsp: 4.335 ± 0.05	4.584AspGlu: 4.584 ± 0.04	2.283AspPhe: 2.283 ± 0.028	3.942AspGly: 3.942 ± 0.028	1.142AspHis: 1.142 ± 0.016	3.268AspIle: 3.268 ± 0.031	2.413AspLys: 2.413 ± 0.026	5.08AspLeu: 5.08 ± 0.037	1.258AspMet: 1.258 ± 0.018	2.024AspAsn: 2.024 ± 0.023	3.043AspPro: 3.043 ± 0.025	1.522AspGln: 1.522 ± 0.019	2.759AspArg: 2.759 ± 0.028	4.461AspSer: 4.461 ± 0.032	2.997AspThr: 2.997 ± 0.029	4.131AspVal: 4.131 ± 0.033	0.81AspTrp: 0.81 ± 0.015	1.501AspTyr: 1.501 ± 0.019	0.015AspXaa: 0.015 ± 0.002
Glu	4.909GluAla: 4.909 ± 0.033	0.603GluCys: 0.603 ± 0.013	4.215GluAsp: 4.215 ± 0.039	5.415GluGlu: 5.415 ± 0.06	1.974GluPhe: 1.974 ± 0.02	3.68GluGly: 3.68 ± 0.032	1.465GluHis: 1.465 ± 0.021	2.945GluIle: 2.945 ± 0.027	3.514GluLys: 3.514 ± 0.033	5.377GluLeu: 5.377 ± 0.038	1.342GluMet: 1.342 ± 0.017	2.328GluAsn: 2.328 ± 0.027	2.579GluPro: 2.579 ± 0.031	2.242GluGln: 2.242 ± 0.024	4.309GluArg: 4.309 ± 0.04	4.23GluSer: 4.23 ± 0.034	3.184GluThr: 3.184 ± 0.03	3.631GluVal: 3.631 ± 0.031	0.873GluTrp: 0.873 ± 0.014	1.494GluTyr: 1.494 ± 0.02	0.011GluXaa: 0.011 ± 0.002
Phe	3.137PheAla: 3.137 ± 0.027	0.544PheCys: 0.544 ± 0.011	2.342PheAsp: 2.342 ± 0.023	2.247PheGlu: 2.247 ± 0.026	1.704PhePhe: 1.704 ± 0.025	2.765PheGly: 2.765 ± 0.029	0.898PheHis: 0.898 ± 0.015	2.076PheIle: 2.076 ± 0.024	1.592PheLys: 1.592 ± 0.019	3.583PheLeu: 3.583 ± 0.035	0.811PheMet: 0.811 ± 0.013	1.38PheAsn: 1.38 ± 0.018	2.036PhePro: 2.036 ± 0.026	1.231PheGln: 1.231 ± 0.017	1.967PheArg: 1.967 ± 0.023	3.476PheSer: 3.476 ± 0.027	2.196PheThr: 2.196 ± 0.022	2.605PheVal: 2.605 ± 0.028	0.518PheTrp: 0.518 ± 0.011	1.068PheTyr: 1.068 ± 0.016	0.053PheXaa: 0.053 ± 0.004
Gly	5.008GlyAla: 5.008 ± 0.047	0.728GlyCys: 0.728 ± 0.014	3.465GlyAsp: 3.465 ± 0.028	3.418GlyGlu: 3.418 ± 0.028	2.419GlyPhe: 2.419 ± 0.025	4.82GlyGly: 4.82 ± 0.056	1.647GlyHis: 1.647 ± 0.023	3.143GlyIle: 3.143 ± 0.027	3.315GlyLys: 3.315 ± 0.031	5.418GlyLeu: 5.418 ± 0.037	1.512GlyMet: 1.512 ± 0.026	2.284GlyAsn: 2.284 ± 0.028	2.966GlyPro: 2.966 ± 0.031	2.089GlyGln: 2.089 ± 0.025	3.884GlyArg: 3.884 ± 0.032	5.557GlySer: 5.557 ± 0.05	3.888GlyThr: 3.888 ± 0.034	3.992GlyVal: 3.992 ± 0.036	0.927GlyTrp: 0.927 ± 0.017	1.747GlyTyr: 1.747 ± 0.022	0.032GlyXaa: 0.032 ± 0.003
His	2.221HisAla: 2.221 ± 0.022	0.313HisCys: 0.313 ± 0.009	1.327HisAsp: 1.327 ± 0.019	1.28HisGlu: 1.28 ± 0.017	1.047HisPhe: 1.047 ± 0.016	1.613HisGly: 1.613 ± 0.019	0.778HisHis: 0.778 ± 0.016	1.344HisIle: 1.344 ± 0.017	0.933HisLys: 0.933 ± 0.015	2.398HisLeu: 2.398 ± 0.023	0.47HisMet: 0.47 ± 0.01	0.966HisAsn: 0.966 ± 0.015	1.79HisPro: 1.79 ± 0.023	0.87HisGln: 0.87 ± 0.015	1.489HisArg: 1.489 ± 0.02	2.218HisSer: 2.218 ± 0.025	1.527HisThr: 1.527 ± 0.019	1.603HisVal: 1.603 ± 0.018	0.322HisTrp: 0.322 ± 0.009	0.724HisTyr: 0.724 ± 0.013	0.009HisXaa: 0.009 ± 0.001
Ile	4.103IleAla: 4.103 ± 0.033	0.687IleCys: 0.687 ± 0.012	3.035IleAsp: 3.035 ± 0.027	2.915IleGlu: 2.915 ± 0.026	2.03IlePhe: 2.03 ± 0.024	2.868IleGly: 2.868 ± 0.03	1.289IleHis: 1.289 ± 0.017	2.727IleIle: 2.727 ± 0.031	2.241IleLys: 2.241 ± 0.024	4.53IleLeu: 4.53 ± 0.038	0.982IleMet: 0.982 ± 0.016	1.842IleAsn: 1.842 ± 0.02	3.266IlePro: 3.266 ± 0.031	1.694IleGln: 1.694 ± 0.023	2.832IleArg: 2.832 ± 0.028	4.19IleSer: 4.19 ± 0.033	2.731IleThr: 2.731 ± 0.026	3.236IleVal: 3.236 ± 0.032	0.668IleTrp: 0.668 ± 0.016	1.389IleTyr: 1.389 ± 0.018	0.015IleXaa: 0.015 ± 0.002
Lys	4.047LysAla: 4.047 ± 0.03	0.554LysCys: 0.554 ± 0.011	2.741LysAsp: 2.741 ± 0.028	3.392LysGlu: 3.392 ± 0.034	1.381LysPhe: 1.381 ± 0.02	2.814LysGly: 2.814 ± 0.029	1.127LysHis: 1.127 ± 0.014	2.056LysIle: 2.056 ± 0.023	3.142LysLys: 3.142 ± 0.037	4.145LysLeu: 4.145 ± 0.039	0.944LysMet: 0.944 ± 0.016	1.746LysAsn: 1.746 ± 0.021	2.52LysPro: 2.52 ± 0.025	1.682LysGln: 1.682 ± 0.022	3.481LysArg: 3.481 ± 0.038	3.415LysSer: 3.415 ± 0.031	2.77LysThr: 2.77 ± 0.027	2.719LysVal: 2.719 ± 0.029	0.647LysTrp: 0.647 ± 0.013	1.269LysTyr: 1.269 ± 0.018	0.066LysXaa: 0.066 ± 0.004
Leu	7.921LeuAla: 7.921 ± 0.047	1.278LeuCys: 1.278 ± 0.019	5.137LeuAsp: 5.137 ± 0.044	5.386LeuGlu: 5.386 ± 0.042	3.52LeuPhe: 3.52 ± 0.037	5.516LeuGly: 5.516 ± 0.036	2.474LeuHis: 2.474 ± 0.027	4.073LeuIle: 4.073 ± 0.034	4.333LeuLys: 4.333 ± 0.035	8.605LeuLeu: 8.605 ± 0.06	1.684LeuMet: 1.684 ± 0.023	3.369LeuAsn: 3.369 ± 0.028	5.992LeuPro: 5.992 ± 0.042	3.625LeuGln: 3.625 ± 0.032	6.1LeuArg: 6.1 ± 0.045	8.597LeuSer: 8.597 ± 0.044	5.281LeuThr: 5.281 ± 0.036	5.471LeuVal: 5.471 ± 0.041	1.06LeuTrp: 1.06 ± 0.015	2.38LeuTyr: 2.38 ± 0.024	0.026LeuXaa: 0.026 ± 0.002
Met	1.74MetAla: 1.74 ± 0.021	0.222MetCys: 0.222 ± 0.008	1.288MetAsp: 1.288 ± 0.018	1.152MetGlu: 1.152 ± 0.014	0.766MetPhe: 0.766 ± 0.013	1.191MetGly: 1.191 ± 0.021	0.597MetHis: 0.597 ± 0.011	0.874MetIle: 0.874 ± 0.013	1.033MetLys: 1.033 ± 0.014	1.842MetLeu: 1.842 ± 0.022	0.505MetMet: 0.505 ± 0.011	0.791MetAsn: 0.791 ± 0.014	1.288MetPro: 1.288 ± 0.016	0.919MetGln: 0.919 ± 0.016	1.349MetArg: 1.349 ± 0.02	2.038MetSer: 2.038 ± 0.024	1.228MetThr: 1.228 ± 0.017	1.061MetVal: 1.061 ± 0.016	0.225MetTrp: 0.225 ± 0.006	0.523MetTyr: 0.523 ± 0.011	0.006MetXaa: 0.006 ± 0.001
Asn	3.511AsnAla: 3.511 ± 0.029	0.371AsnCys: 0.371 ± 0.01	2.03AsnAsp: 2.03 ± 0.022	2.151AsnGlu: 2.151 ± 0.022	1.473AsnPhe: 1.473 ± 0.021	2.745AsnGly: 2.745 ± 0.024	0.791AsnHis: 0.791 ± 0.012	2.186AsnIle: 2.186 ± 0.025	1.498AsnLys: 1.498 ± 0.019	3.215AsnLeu: 3.215 ± 0.032	0.808AsnMet: 0.808 ± 0.013	1.459AsnAsn: 1.459 ± 0.023	2.228AsnPro: 2.228 ± 0.027	1.137AsnGln: 1.137 ± 0.015	1.735AsnArg: 1.735 ± 0.019	3.004AsnSer: 3.004 ± 0.03	2.364AsnThr: 2.364 ± 0.024	2.564AsnVal: 2.564 ± 0.026	0.491AsnTrp: 0.491 ± 0.012	0.994AsnTyr: 0.994 ± 0.013	0.01AsnXaa: 0.01 ± 0.001
Pro	5.276ProAla: 5.276 ± 0.045	0.527ProCys: 0.527 ± 0.012	3.188ProAsp: 3.188 ± 0.028	3.445ProGlu: 3.445 ± 0.03	2.275ProPhe: 2.275 ± 0.027	3.438ProGly: 3.438 ± 0.034	1.495ProHis: 1.495 ± 0.021	2.695ProIle: 2.695 ± 0.024	2.272ProLys: 2.272 ± 0.025	5.411ProLeu: 5.411 ± 0.036	1.065ProMet: 1.065 ± 0.018	2.221ProAsn: 2.221 ± 0.025	5.652ProPro: 5.652 ± 0.065	2.205ProGln: 2.205 ± 0.025	3.288ProArg: 3.288 ± 0.03	7.187ProSer: 7.187 ± 0.063	4.37ProThr: 4.37 ± 0.043	3.801ProVal: 3.801 ± 0.034	0.621ProTrp: 0.621 ± 0.011	1.488ProTyr: 1.488 ± 0.019	0.061ProXaa: 0.061 ± 0.004
Gln	3.077GlnAla: 3.077 ± 0.029	0.411GlnCys: 0.411 ± 0.01	1.72GlnAsp: 1.72 ± 0.018	2.074GlnGlu: 2.074 ± 0.02	1.26GlnPhe: 1.26 ± 0.016	1.895GlnGly: 1.895 ± 0.026	1.092GlnHis: 1.092 ± 0.017	1.734GlnIle: 1.734 ± 0.021	1.64GlnLys: 1.64 ± 0.021	3.258GlnLeu: 3.258 ± 0.03	0.825GlnMet: 0.825 ± 0.014	1.456GlnAsn: 1.456 ± 0.021	2.227GlnPro: 2.227 ± 0.029	2.255GlnGln: 2.255 ± 0.054	2.509GlnArg: 2.509 ± 0.025	3.148GlnSer: 3.148 ± 0.03	2.426GlnThr: 2.426 ± 0.024	2.019GlnVal: 2.019 ± 0.021	0.465GlnTrp: 0.465 ± 0.011	0.971GlnTyr: 0.971 ± 0.016	0.013GlnXaa: 0.013 ± 0.002
Arg	5.219ArgAla: 5.219 ± 0.037	0.706ArgCys: 0.706 ± 0.012	3.233ArgAsp: 3.233 ± 0.03	3.837ArgGlu: 3.837 ± 0.041	2.182ArgPhe: 2.182 ± 0.022	3.486ArgGly: 3.486 ± 0.035	1.569ArgHis: 1.569 ± 0.02	3.102ArgIle: 3.102 ± 0.026	3.435ArgLys: 3.435 ± 0.031	5.649ArgLeu: 5.649 ± 0.038	1.313ArgMet: 1.313 ± 0.018	2.163ArgAsn: 2.163 ± 0.024	3.582ArgPro: 3.582 ± 0.034	2.3ArgGln: 2.3 ± 0.026	5.339ArgArg: 5.339 ± 0.047	5.32ArgSer: 5.32 ± 0.043	3.667ArgThr: 3.667 ± 0.033	3.586ArgVal: 3.586 ± 0.03	0.807ArgTrp: 0.807 ± 0.014	1.452ArgTyr: 1.452 ± 0.019	0.021ArgXaa: 0.021 ± 0.002
Ser	7.824SerAla: 7.824 ± 0.055	0.87SerCys: 0.87 ± 0.017	4.784SerAsp: 4.784 ± 0.037	4.565SerGlu: 4.565 ± 0.039	3.375SerPhe: 3.375 ± 0.029	5.732SerGly: 5.732 ± 0.048	2.129SerHis: 2.129 ± 0.025	4.159SerIle: 4.159 ± 0.03	3.731SerLys: 3.731 ± 0.032	8.196SerLeu: 8.196 ± 0.048	1.835SerMet: 1.835 ± 0.02	3.125SerAsn: 3.125 ± 0.03	6.609SerPro: 6.609 ± 0.064	3.154SerGln: 3.154 ± 0.032	5.352SerArg: 5.352 ± 0.044	11.322SerSer: 11.322 ± 0.097	6.37SerThr: 6.37 ± 0.048	5.419SerVal: 5.419 ± 0.04	0.959SerTrp: 0.959 ± 0.015	2.043SerTyr: 2.043 ± 0.024	0.022SerXaa: 0.022 ± 0.002
Thr	4.888ThrAla: 4.888 ± 0.035	0.709ThrCys: 0.709 ± 0.013	3.017ThrAsp: 3.017 ± 0.031	2.929ThrGlu: 2.929 ± 0.026	2.405ThrPhe: 2.405 ± 0.025	3.717ThrGly: 3.717 ± 0.035	1.596ThrHis: 1.596 ± 0.018	3.168ThrIle: 3.168 ± 0.027	2.502ThrLys: 2.502 ± 0.029	5.622ThrLeu: 5.622 ± 0.039	1.168ThrMet: 1.168 ± 0.016	2.246ThrAsn: 2.246 ± 0.021	4.766ThrPro: 4.766 ± 0.048	2.137ThrGln: 2.137 ± 0.022	3.421ThrArg: 3.421 ± 0.025	6.127ThrSer: 6.127 ± 0.054	4.229ThrThr: 4.229 ± 0.042	3.601ThrVal: 3.601 ± 0.029	0.742ThrTrp: 0.742 ± 0.014	1.484ThrTyr: 1.484 ± 0.02	0.023ThrXaa: 0.023 ± 0.002
Val	5.063ValAla: 5.063 ± 0.038	0.776ValCys: 0.776 ± 0.013	4.003ValAsp: 4.003 ± 0.032	3.798ValGlu: 3.798 ± 0.034	2.596ValPhe: 2.596 ± 0.027	3.608ValGly: 3.608 ± 0.032	1.657ValHis: 1.657 ± 0.02	2.944ValIle: 2.944 ± 0.029	2.929ValLys: 2.929 ± 0.032	6.129ValLeu: 6.129 ± 0.042	1.234ValMet: 1.234 ± 0.017	2.206ValAsn: 2.206 ± 0.026	3.778ValPro: 3.778 ± 0.03	2.42ValGln: 2.42 ± 0.022	3.63ValArg: 3.63 ± 0.032	5.173ValSer: 5.173 ± 0.035	3.298ValThr: 3.298 ± 0.026	4.156ValVal: 4.156 ± 0.038	0.821ValTrp: 0.821 ± 0.016	1.763ValTyr: 1.763 ± 0.019	0.016ValXaa: 0.016 ± 0.002
Trp	0.998TrpAla: 0.998 ± 0.015	0.175TrpCys: 0.175 ± 0.006	0.832TrpAsp: 0.832 ± 0.017	0.778TrpGlu: 0.778 ± 0.016	0.492TrpPhe: 0.492 ± 0.013	0.721TrpGly: 0.721 ± 0.014	0.306TrpHis: 0.306 ± 0.008	0.643TrpIle: 0.643 ± 0.014	0.771TrpLys: 0.771 ± 0.013	1.182TrpLeu: 1.182 ± 0.018	0.299TrpMet: 0.299 ± 0.008	0.567TrpAsn: 0.567 ± 0.011	0.572TrpPro: 0.572 ± 0.012	0.401TrpGln: 0.401 ± 0.009	0.882TrpArg: 0.882 ± 0.014	0.952TrpSer: 0.952 ± 0.014	0.826TrpThr: 0.826 ± 0.017	0.734TrpVal: 0.734 ± 0.015	0.266TrpTrp: 0.266 ± 0.009	0.363TrpTyr: 0.363 ± 0.009	0.004TrpXaa: 0.004 ± 0.001
Tyr	2.259TyrAla: 2.259 ± 0.026	0.383TyrCys: 0.383 ± 0.01	1.662TyrAsp: 1.662 ± 0.022	1.455TyrGlu: 1.455 ± 0.021	1.105TyrPhe: 1.105 ± 0.018	1.691TyrGly: 1.691 ± 0.023	0.728TyrHis: 0.728 ± 0.013	1.386TyrIle: 1.386 ± 0.019	1.092TyrLys: 1.092 ± 0.017	2.42TyrLeu: 2.42 ± 0.027	0.558TyrMet: 0.558 ± 0.011	1.08TyrAsn: 1.08 ± 0.016	1.449TyrPro: 1.449 ± 0.02	0.879TyrGln: 0.879 ± 0.016	1.503TyrArg: 1.503 ± 0.02	2.063TyrSer: 2.063 ± 0.023	1.502TyrThr: 1.502 ± 0.02	1.635TyrVal: 1.635 ± 0.021	0.344TyrTrp: 0.344 ± 0.009	0.794TyrTyr: 0.794 ± 0.014	0.008TyrXaa: 0.008 ± 0.001
Xaa	0.03XaaAla: 0.03 ± 0.003	0.007XaaCys: 0.007 ± 0.001	0.016XaaAsp: 0.016 ± 0.003	0.013XaaGlu: 0.013 ± 0.002	0.049XaaPhe: 0.049 ± 0.004	0.045XaaGly: 0.045 ± 0.003	0.009XaaHis: 0.009 ± 0.001	0.012XaaIle: 0.012 ± 0.002	0.054XaaLys: 0.054 ± 0.004	0.024XaaLeu: 0.024 ± 0.003	0.005XaaMet: 0.005 ± 0.001	0.01XaaAsn: 0.01 ± 0.002	0.06XaaPro: 0.06 ± 0.004	0.009XaaGln: 0.009 ± 0.001	0.028XaaArg: 0.028 ± 0.002	0.021XaaSer: 0.021 ± 0.002	0.02XaaThr: 0.02 ± 0.003	0.018XaaVal: 0.018 ± 0.002	0.007XaaTrp: 0.007 ± 0.001	0.007XaaTyr: 0.007 ± 0.001	0.011XaaXaa: 0.011 ± 0.003

Statistics based on 8697 proteins (4555891 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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