Amino acid dipepetide frequency for Eimeria praecox

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	78.736AlaAla: 78.736 ± 1.063	1.397AlaCys: 1.397 ± 0.029	4.599AlaAsp: 4.599 ± 0.075	7.185AlaGlu: 7.185 ± 0.103	2.184AlaPhe: 2.184 ± 0.028	6.43AlaGly: 6.43 ± 0.054	1.283AlaHis: 1.283 ± 0.022	2.24AlaIle: 2.24 ± 0.028	2.756AlaLys: 2.756 ± 0.041	7.101AlaLeu: 7.101 ± 0.072	1.036AlaMet: 1.036 ± 0.022	1.862AlaAsn: 1.862 ± 0.027	6.417AlaPro: 6.417 ± 0.092	2.895AlaGln: 2.895 ± 0.039	3.979AlaArg: 3.979 ± 0.043	7.732AlaSer: 7.732 ± 0.068	10.023AlaThr: 10.023 ± 0.128	6.278AlaVal: 6.278 ± 0.062	0.654AlaTrp: 0.654 ± 0.015	1.184AlaTyr: 1.184 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	1.039CysAla: 1.039 ± 0.02	1.518CysCys: 1.518 ± 0.039	0.434CysAsp: 0.434 ± 0.012	0.607CysGlu: 0.607 ± 0.016	0.619CysPhe: 0.619 ± 0.014	1.073CysGly: 1.073 ± 0.026	0.218CysHis: 0.218 ± 0.009	0.655CysIle: 0.655 ± 0.015	0.479CysLys: 0.479 ± 0.014	1.853CysLeu: 1.853 ± 0.025	0.411CysMet: 0.411 ± 0.012	0.4CysAsn: 0.4 ± 0.013	0.72CysPro: 0.72 ± 0.04	0.399CysGln: 0.399 ± 0.014	1.014CysArg: 1.014 ± 0.019	2.56CysSer: 2.56 ± 0.041	0.728CysThr: 0.728 ± 0.017	0.891CysVal: 0.891 ± 0.016	0.23CysTrp: 0.23 ± 0.009	0.297CysTyr: 0.297 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.18AspAla: 4.18 ± 0.068	0.651AspCys: 0.651 ± 0.021	2.116AspAsp: 2.116 ± 0.049	2.582AspGlu: 2.582 ± 0.034	0.931AspPhe: 0.931 ± 0.021	2.232AspGly: 2.232 ± 0.035	0.404AspHis: 0.404 ± 0.012	1.535AspIle: 1.535 ± 0.024	1.432AspLys: 1.432 ± 0.043	2.818AspLeu: 2.818 ± 0.031	0.661AspMet: 0.661 ± 0.014	0.864AspAsn: 0.864 ± 0.017	1.792AspPro: 1.792 ± 0.028	0.924AspGln: 0.924 ± 0.02	2.595AspArg: 2.595 ± 0.08	3.474AspSer: 3.474 ± 0.042	2.259AspThr: 2.259 ± 0.039	1.976AspVal: 1.976 ± 0.03	0.362AspTrp: 0.362 ± 0.012	0.543AspTyr: 0.543 ± 0.013	0.0AspXaa: 0.0 ± 0.0
Glu	7.898GluAla: 7.898 ± 0.115	0.68GluCys: 0.68 ± 0.017	3.098GluAsp: 3.098 ± 0.043	8.989GluGlu: 8.989 ± 0.186	0.963GluPhe: 0.963 ± 0.02	4.779GluGly: 4.779 ± 0.06	0.92GluHis: 0.92 ± 0.019	1.47GluIle: 1.47 ± 0.025	2.797GluLys: 2.797 ± 0.054	4.343GluLeu: 4.343 ± 0.057	0.874GluMet: 0.874 ± 0.017	1.151GluAsn: 1.151 ± 0.024	1.971GluPro: 1.971 ± 0.028	5.636GluGln: 5.636 ± 0.082	3.787GluArg: 3.787 ± 0.062	2.897GluSer: 2.897 ± 0.037	4.457GluThr: 4.457 ± 0.078	2.611GluVal: 2.611 ± 0.04	0.468GluTrp: 0.468 ± 0.013	0.737GluTyr: 0.737 ± 0.014	0.0GluXaa: 0.0 ± 0.0
Phe	2.021PheAla: 2.021 ± 0.025	0.593PheCys: 0.593 ± 0.014	0.964PheAsp: 0.964 ± 0.023	1.16PheGlu: 1.16 ± 0.023	0.858PhePhe: 0.858 ± 0.018	1.301PheGly: 1.301 ± 0.026	0.38PheHis: 0.38 ± 0.011	0.775PheIle: 0.775 ± 0.017	0.741PheLys: 0.741 ± 0.015	2.303PheLeu: 2.303 ± 0.031	0.377PheMet: 0.377 ± 0.009	0.561PheAsn: 0.561 ± 0.014	1.052PhePro: 1.052 ± 0.021	0.656PheGln: 0.656 ± 0.016	1.132PheArg: 1.132 ± 0.023	1.931PheSer: 1.931 ± 0.026	0.851PheThr: 0.851 ± 0.019	1.562PheVal: 1.562 ± 0.026	0.226PheTrp: 0.226 ± 0.009	0.49PheTyr: 0.49 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	6.425GlyAla: 6.425 ± 0.072	1.111GlyCys: 1.111 ± 0.02	2.997GlyAsp: 2.997 ± 0.046	3.586GlyGlu: 3.586 ± 0.043	1.484GlyPhe: 1.484 ± 0.022	6.121GlyGly: 6.121 ± 0.097	0.759GlyHis: 0.759 ± 0.02	1.526GlyIle: 1.526 ± 0.029	1.613GlyLys: 1.613 ± 0.033	4.222GlyLeu: 4.222 ± 0.049	0.789GlyMet: 0.789 ± 0.019	1.106GlyAsn: 1.106 ± 0.022	3.597GlyPro: 3.597 ± 0.09	1.672GlyGln: 1.672 ± 0.028	3.115GlyArg: 3.115 ± 0.036	4.884GlySer: 4.884 ± 0.063	2.375GlyThr: 2.375 ± 0.039	3.179GlyVal: 3.179 ± 0.035	0.515GlyTrp: 0.515 ± 0.012	0.856GlyTyr: 0.856 ± 0.019	0.0GlyXaa: 0.0 ± 0.0
His	1.627HisAla: 1.627 ± 0.025	0.341HisCys: 0.341 ± 0.01	0.566HisAsp: 0.566 ± 0.015	1.245HisGlu: 1.245 ± 0.024	0.501HisPhe: 0.501 ± 0.013	0.865HisGly: 0.865 ± 0.019	1.734HisHis: 1.734 ± 0.059	0.7HisIle: 0.7 ± 0.015	0.771HisLys: 0.771 ± 0.016	2.23HisLeu: 2.23 ± 0.033	0.414HisMet: 0.414 ± 0.014	0.46HisAsn: 0.46 ± 0.011	1.338HisPro: 1.338 ± 0.022	3.489HisGln: 3.489 ± 0.074	1.438HisArg: 1.438 ± 0.021	1.549HisSer: 1.549 ± 0.021	0.989HisThr: 0.989 ± 0.019	0.831HisVal: 0.831 ± 0.019	0.182HisTrp: 0.182 ± 0.007	0.367HisTyr: 0.367 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	2.296IleAla: 2.296 ± 0.03	0.667IleCys: 0.667 ± 0.016	1.144IleAsp: 1.144 ± 0.02	1.724IleGlu: 1.724 ± 0.029	0.76IlePhe: 0.76 ± 0.015	1.213IleGly: 1.213 ± 0.025	0.626IleHis: 0.626 ± 0.015	1.149IleIle: 1.149 ± 0.048	1.09IleLys: 1.09 ± 0.02	2.132IleLeu: 2.132 ± 0.033	0.426IleMet: 0.426 ± 0.014	1.007IleAsn: 1.007 ± 0.034	1.389IlePro: 1.389 ± 0.023	1.331IleGln: 1.331 ± 0.022	1.54IleArg: 1.54 ± 0.027	2.341IleSer: 2.341 ± 0.032	1.144IleThr: 1.144 ± 0.025	1.311IleVal: 1.311 ± 0.023	0.24IleTrp: 0.24 ± 0.009	0.556IleTyr: 0.556 ± 0.013	0.0IleXaa: 0.0 ± 0.0
Lys	2.939LysAla: 2.939 ± 0.045	0.44LysCys: 0.44 ± 0.014	1.455LysAsp: 1.455 ± 0.027	3.34LysGlu: 3.34 ± 0.07	0.511LysPhe: 0.511 ± 0.016	2.18LysGly: 2.18 ± 0.039	0.814LysHis: 0.814 ± 0.017	0.982LysIle: 0.982 ± 0.022	2.583LysLys: 2.583 ± 0.072	2.557LysLeu: 2.557 ± 0.036	0.551LysMet: 0.551 ± 0.013	0.903LysAsn: 0.903 ± 0.019	1.68LysPro: 1.68 ± 0.036	3.888LysGln: 3.888 ± 0.051	2.437LysArg: 2.437 ± 0.035	1.741LysSer: 1.741 ± 0.028	1.953LysThr: 1.953 ± 0.033	1.247LysVal: 1.247 ± 0.025	0.252LysTrp: 0.252 ± 0.009	0.559LysTyr: 0.559 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	5.876LeuAla: 5.876 ± 0.059	1.503LeuCys: 1.503 ± 0.026	2.597LeuAsp: 2.597 ± 0.036	4.373LeuGlu: 4.373 ± 0.061	2.13LeuPhe: 2.13 ± 0.033	3.826LeuGly: 3.826 ± 0.05	2.38LeuHis: 2.38 ± 0.03	1.936LeuIle: 1.936 ± 0.028	3.049LeuLys: 3.049 ± 0.043	16.909LeuLeu: 16.909 ± 0.207	1.392LeuMet: 1.392 ± 0.026	1.722LeuAsn: 1.722 ± 0.029	5.316LeuPro: 5.316 ± 0.053	12.292LeuGln: 12.292 ± 0.161	5.754LeuArg: 5.754 ± 0.055	6.259LeuSer: 6.259 ± 0.06	2.989LeuThr: 2.989 ± 0.036	3.48LeuVal: 3.48 ± 0.043	0.867LeuTrp: 0.867 ± 0.015	1.399LeuTyr: 1.399 ± 0.02	0.0LeuXaa: 0.0 ± 0.0
Met	0.966MetAla: 0.966 ± 0.021	0.213MetCys: 0.213 ± 0.008	0.436MetAsp: 0.436 ± 0.011	0.842MetGlu: 0.842 ± 0.017	0.318MetPhe: 0.318 ± 0.011	0.813MetGly: 0.813 ± 0.022	0.408MetHis: 0.408 ± 0.012	0.373MetIle: 0.373 ± 0.015	0.705MetLys: 0.705 ± 0.014	1.801MetLeu: 1.801 ± 0.025	0.414MetMet: 0.414 ± 0.022	0.341MetAsn: 0.341 ± 0.011	0.73MetPro: 0.73 ± 0.015	1.593MetGln: 1.593 ± 0.027	0.989MetArg: 0.989 ± 0.017	0.831MetSer: 0.831 ± 0.018	0.554MetThr: 0.554 ± 0.013	0.57MetVal: 0.57 ± 0.018	0.159MetTrp: 0.159 ± 0.007	0.265MetTyr: 0.265 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	1.85AsnAla: 1.85 ± 0.031	0.497AsnCys: 0.497 ± 0.013	0.78AsnAsp: 0.78 ± 0.018	1.169AsnGlu: 1.169 ± 0.023	0.478AsnPhe: 0.478 ± 0.014	1.153AsnGly: 1.153 ± 0.025	0.338AsnHis: 0.338 ± 0.01	1.001AsnIle: 1.001 ± 0.025	1.23AsnLys: 1.23 ± 0.028	1.511AsnLeu: 1.511 ± 0.026	0.364AsnMet: 0.364 ± 0.012	2.394AsnAsn: 2.394 ± 0.083	1.245AsnPro: 1.245 ± 0.022	0.803AsnGln: 0.803 ± 0.017	1.312AsnArg: 1.312 ± 0.023	5.794AsnSer: 5.794 ± 0.117	1.587AsnThr: 1.587 ± 0.033	0.911AsnVal: 0.911 ± 0.02	0.164AsnTrp: 0.164 ± 0.006	0.379AsnTyr: 0.379 ± 0.011	0.0AsnXaa: 0.0 ± 0.0
Pro	6.767ProAla: 6.767 ± 0.074	0.791ProCys: 0.791 ± 0.026	1.476ProAsp: 1.476 ± 0.03	2.704ProGlu: 2.704 ± 0.042	1.347ProPhe: 1.347 ± 0.027	2.37ProGly: 2.37 ± 0.044	1.395ProHis: 1.395 ± 0.021	1.133ProIle: 1.133 ± 0.024	1.601ProLys: 1.601 ± 0.039	5.284ProLeu: 5.284 ± 0.063	0.704ProMet: 0.704 ± 0.017	0.96ProAsn: 0.96 ± 0.017	5.717ProPro: 5.717 ± 0.087	3.916ProGln: 3.916 ± 0.058	2.457ProArg: 2.457 ± 0.034	4.837ProSer: 4.837 ± 0.054	2.883ProThr: 2.883 ± 0.039	2.533ProVal: 2.533 ± 0.04	0.56ProTrp: 0.56 ± 0.014	0.829ProTyr: 0.829 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	3.215GlnAla: 3.215 ± 0.045	0.468GlnCys: 0.468 ± 0.014	1.804GlnAsp: 1.804 ± 0.027	5.721GlnGlu: 5.721 ± 0.077	0.708GlnPhe: 0.708 ± 0.015	2.633GlnGly: 2.633 ± 0.036	5.292GlnHis: 5.292 ± 0.092	1.404GlnIle: 1.404 ± 0.021	3.019GlnLys: 3.019 ± 0.046	9.018GlnLeu: 9.018 ± 0.129	1.16GlnMet: 1.16 ± 0.022	1.052GlnAsn: 1.052 ± 0.021	3.398GlnPro: 3.398 ± 0.055	95.874GlnGln: 95.874 ± 1.319	5.047GlnArg: 5.047 ± 0.066	2.117GlnSer: 2.117 ± 0.028	2.534GlnThr: 2.534 ± 0.029	2.001GlnVal: 2.001 ± 0.03	0.452GlnTrp: 0.452 ± 0.012	0.68GlnTyr: 0.68 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	4.173ArgAla: 4.173 ± 0.044	1.201ArgCys: 1.201 ± 0.021	2.532ArgAsp: 2.532 ± 0.06	4.192ArgGlu: 4.192 ± 0.06	1.229ArgPhe: 1.229 ± 0.023	3.737ArgGly: 3.737 ± 0.049	1.416ArgHis: 1.416 ± 0.023	1.626ArgIle: 1.626 ± 0.023	2.313ArgLys: 2.313 ± 0.032	5.293ArgLeu: 5.293 ± 0.053	1.063ArgMet: 1.063 ± 0.017	1.32ArgAsn: 1.32 ± 0.023	2.319ArgPro: 2.319 ± 0.03	4.717ArgGln: 4.717 ± 0.064	5.644ArgArg: 5.644 ± 0.079	4.495ArgSer: 4.495 ± 0.049	2.104ArgThr: 2.104 ± 0.028	2.474ArgVal: 2.474 ± 0.033	0.619ArgTrp: 0.619 ± 0.014	0.848ArgTyr: 0.848 ± 0.016	0.0ArgXaa: 0.0 ± 0.0
Ser	7.176SerAla: 7.176 ± 0.06	1.87SerCys: 1.87 ± 0.032	2.515SerAsp: 2.515 ± 0.035	3.306SerGlu: 3.306 ± 0.036	2.026SerPhe: 2.026 ± 0.031	4.136SerGly: 4.136 ± 0.055	1.156SerHis: 1.156 ± 0.02	2.426SerIle: 2.426 ± 0.041	3.0SerLys: 3.0 ± 0.034	6.432SerLeu: 6.432 ± 0.058	1.011SerMet: 1.011 ± 0.019	5.91SerAsn: 5.91 ± 0.121	4.84SerPro: 4.84 ± 0.059	2.344SerGln: 2.344 ± 0.032	4.985SerArg: 4.985 ± 0.048	32.918SerSer: 32.918 ± 0.51	4.252SerThr: 4.252 ± 0.052	3.565SerVal: 3.565 ± 0.039	0.682SerTrp: 0.682 ± 0.016	1.066SerTyr: 1.066 ± 0.019	0.001SerXaa: 0.001 ± 0.0
Thr	11.67ThrAla: 11.67 ± 0.135	0.64ThrCys: 0.64 ± 0.018	1.988ThrAsp: 1.988 ± 0.041	3.623ThrGlu: 3.623 ± 0.064	0.863ThrPhe: 0.863 ± 0.019	2.576ThrGly: 2.576 ± 0.038	0.824ThrHis: 0.824 ± 0.015	1.198ThrIle: 1.198 ± 0.026	1.493ThrLys: 1.493 ± 0.029	3.157ThrLeu: 3.157 ± 0.034	0.497ThrMet: 0.497 ± 0.014	1.43ThrAsn: 1.43 ± 0.037	3.543ThrPro: 3.543 ± 0.042	1.927ThrGln: 1.927 ± 0.023	2.08ThrArg: 2.08 ± 0.03	3.569ThrSer: 3.569 ± 0.041	4.396ThrThr: 4.396 ± 0.069	2.202ThrVal: 2.202 ± 0.036	0.322ThrTrp: 0.322 ± 0.01	0.65ThrTyr: 0.65 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	5.508ValAla: 5.508 ± 0.06	1.069ValCys: 1.069 ± 0.019	1.958ValAsp: 1.958 ± 0.031	2.894ValGlu: 2.894 ± 0.043	1.366ValPhe: 1.366 ± 0.022	2.78ValGly: 2.78 ± 0.035	0.847ValHis: 0.847 ± 0.018	1.067ValIle: 1.067 ± 0.025	1.411ValLys: 1.411 ± 0.023	4.687ValLeu: 4.687 ± 0.049	0.721ValMet: 0.721 ± 0.019	0.888ValAsn: 0.888 ± 0.018	2.136ValPro: 2.136 ± 0.035	2.116ValGln: 2.116 ± 0.033	2.212ValArg: 2.212 ± 0.032	4.003ValSer: 4.003 ± 0.044	1.415ValThr: 1.415 ± 0.03	2.874ValVal: 2.874 ± 0.044	0.483ValTrp: 0.483 ± 0.012	1.173ValTyr: 1.173 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	0.575TrpAla: 0.575 ± 0.013	0.165TrpCys: 0.165 ± 0.008	0.302TrpAsp: 0.302 ± 0.01	0.481TrpGlu: 0.481 ± 0.011	0.192TrpPhe: 0.192 ± 0.008	0.854TrpGly: 0.854 ± 0.017	0.161TrpHis: 0.161 ± 0.006	0.268TrpIle: 0.268 ± 0.009	0.341TrpLys: 0.341 ± 0.011	0.923TrpLeu: 0.923 ± 0.018	0.177TrpMet: 0.177 ± 0.007	0.192TrpAsn: 0.192 ± 0.008	0.327TrpPro: 0.327 ± 0.01	0.544TrpGln: 0.544 ± 0.013	0.814TrpArg: 0.814 ± 0.017	0.518TrpSer: 0.518 ± 0.013	0.288TrpThr: 0.288 ± 0.011	0.364TrpVal: 0.364 ± 0.011	0.145TrpTrp: 0.145 ± 0.006	0.099TrpTyr: 0.099 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.033TyrAla: 1.033 ± 0.019	0.331TyrCys: 0.331 ± 0.016	0.571TyrAsp: 0.571 ± 0.016	0.803TyrGlu: 0.803 ± 0.018	0.465TyrPhe: 0.465 ± 0.011	0.86TyrGly: 0.86 ± 0.019	0.28TyrHis: 0.28 ± 0.009	0.619TyrIle: 0.619 ± 0.015	0.589TyrLys: 0.589 ± 0.015	1.476TyrLeu: 1.476 ± 0.023	0.28TyrMet: 0.28 ± 0.01	0.437TyrAsn: 0.437 ± 0.013	0.736TyrPro: 0.736 ± 0.017	0.582TyrGln: 0.582 ± 0.014	0.984TyrArg: 0.984 ± 0.023	1.169TyrSer: 1.169 ± 0.021	0.865TyrThr: 0.865 ± 0.017	0.747TyrVal: 0.747 ± 0.017	0.149TyrTrp: 0.149 ± 0.008	0.338TyrTyr: 0.338 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 7635 proteins (3653206 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---