Amino acid dipepetide frequency for Xenorhabdus szentirmaii DSM 16338

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.962AlaAla: 6.962 ± 0.1	0.974AlaCys: 0.974 ± 0.032	4.192AlaAsp: 4.192 ± 0.064	5.326AlaGlu: 5.326 ± 0.081	3.194AlaPhe: 3.194 ± 0.05	6.047AlaGly: 6.047 ± 0.083	1.639AlaHis: 1.639 ± 0.037	5.679AlaIle: 5.679 ± 0.078	4.119AlaLys: 4.119 ± 0.074	9.259AlaLeu: 9.259 ± 0.106	2.271AlaMet: 2.271 ± 0.049	3.278AlaAsn: 3.278 ± 0.067	2.777AlaPro: 2.777 ± 0.057	3.544AlaGln: 3.544 ± 0.061	3.985AlaArg: 3.985 ± 0.065	4.592AlaSer: 4.592 ± 0.069	3.923AlaThr: 3.923 ± 0.067	5.224AlaVal: 5.224 ± 0.069	0.993AlaTrp: 0.993 ± 0.026	2.308AlaTyr: 2.308 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	0.803CysAla: 0.803 ± 0.026	0.191CysCys: 0.191 ± 0.015	0.568CysAsp: 0.568 ± 0.024	0.603CysGlu: 0.603 ± 0.022	0.498CysPhe: 0.498 ± 0.02	0.98CysGly: 0.98 ± 0.029	0.419CysHis: 0.419 ± 0.022	0.737CysIle: 0.737 ± 0.027	0.372CysLys: 0.372 ± 0.018	1.166CysLeu: 1.166 ± 0.034	0.242CysMet: 0.242 ± 0.014	0.391CysAsn: 0.391 ± 0.018	0.492CysPro: 0.492 ± 0.021	0.563CysGln: 0.563 ± 0.023	0.6CysArg: 0.6 ± 0.021	0.754CysSer: 0.754 ± 0.026	0.502CysThr: 0.502 ± 0.018	0.616CysVal: 0.616 ± 0.022	0.197CysTrp: 0.197 ± 0.012	0.427CysTyr: 0.427 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	4.113AspAla: 4.113 ± 0.063	0.577AspCys: 0.577 ± 0.022	2.671AspAsp: 2.671 ± 0.052	3.506AspGlu: 3.506 ± 0.056	2.307AspPhe: 2.307 ± 0.046	3.605AspGly: 3.605 ± 0.08	1.069AspHis: 1.069 ± 0.029	4.305AspIle: 4.305 ± 0.061	3.025AspLys: 3.025 ± 0.064	4.629AspLeu: 4.629 ± 0.067	1.318AspMet: 1.318 ± 0.033	2.624AspAsn: 2.624 ± 0.05	2.099AspPro: 2.099 ± 0.048	1.634AspGln: 1.634 ± 0.041	2.294AspArg: 2.294 ± 0.046	3.124AspSer: 3.124 ± 0.06	2.592AspThr: 2.592 ± 0.048	3.318AspVal: 3.318 ± 0.043	0.841AspTrp: 0.841 ± 0.028	2.041AspTyr: 2.041 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	4.462GluAla: 4.462 ± 0.06	0.587GluCys: 0.587 ± 0.026	2.464GluAsp: 2.464 ± 0.044	3.659GluGlu: 3.659 ± 0.066	2.158GluPhe: 2.158 ± 0.036	3.384GluGly: 3.384 ± 0.047	1.651GluHis: 1.651 ± 0.036	4.315GluIle: 4.315 ± 0.066	4.411GluLys: 4.411 ± 0.076	6.639GluLeu: 6.639 ± 0.088	1.734GluMet: 1.734 ± 0.038	3.052GluAsn: 3.052 ± 0.052	2.05GluPro: 2.05 ± 0.043	3.697GluGln: 3.697 ± 0.063	3.56GluArg: 3.56 ± 0.051	3.552GluSer: 3.552 ± 0.054	3.126GluThr: 3.126 ± 0.058	3.295GluVal: 3.295 ± 0.062	0.858GluTrp: 0.858 ± 0.029	1.916GluTyr: 1.916 ± 0.041	0.0GluXaa: 0.0 ± 0.0
Phe	3.005PheAla: 3.005 ± 0.048	0.578PheCys: 0.578 ± 0.022	2.489PheAsp: 2.489 ± 0.048	2.073PheGlu: 2.073 ± 0.045	1.869PhePhe: 1.869 ± 0.046	2.999PheGly: 2.999 ± 0.052	0.956PheHis: 0.956 ± 0.029	3.154PheIle: 3.154 ± 0.061	1.713PheLys: 1.713 ± 0.039	3.618PheLeu: 3.618 ± 0.06	1.05PheMet: 1.05 ± 0.029	2.18PheAsn: 2.18 ± 0.042	1.651PhePro: 1.651 ± 0.036	1.237PheGln: 1.237 ± 0.03	1.807PheArg: 1.807 ± 0.041	3.552PheSer: 3.552 ± 0.056	2.32PheThr: 2.32 ± 0.044	2.358PheVal: 2.358 ± 0.053	0.6PheTrp: 0.6 ± 0.025	1.423PheTyr: 1.423 ± 0.038	0.0PheXaa: 0.0 ± 0.0
Gly	4.949GlyAla: 4.949 ± 0.076	0.898GlyCys: 0.898 ± 0.028	3.359GlyAsp: 3.359 ± 0.071	4.205GlyGlu: 4.205 ± 0.067	3.031GlyPhe: 3.031 ± 0.057	4.734GlyGly: 4.734 ± 0.071	1.67GlyHis: 1.67 ± 0.037	5.393GlyIle: 5.393 ± 0.074	4.341GlyLys: 4.341 ± 0.065	6.678GlyLeu: 6.678 ± 0.078	2.071GlyMet: 2.071 ± 0.042	3.051GlyAsn: 3.051 ± 0.081	1.624GlyPro: 1.624 ± 0.032	2.838GlyGln: 2.838 ± 0.052	3.374GlyArg: 3.374 ± 0.062	4.028GlySer: 4.028 ± 0.056	3.393GlyThr: 3.393 ± 0.056	4.713GlyVal: 4.713 ± 0.078	1.109GlyTrp: 1.109 ± 0.031	2.668GlyTyr: 2.668 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	1.746HisAla: 1.746 ± 0.042	0.391HisCys: 0.391 ± 0.018	1.249HisAsp: 1.249 ± 0.031	1.293HisGlu: 1.293 ± 0.033	1.211HisPhe: 1.211 ± 0.03	1.614HisGly: 1.614 ± 0.042	0.877HisHis: 0.877 ± 0.029	1.724HisIle: 1.724 ± 0.044	1.045HisLys: 1.045 ± 0.029	2.507HisLeu: 2.507 ± 0.045	0.544HisMet: 0.544 ± 0.021	0.958HisAsn: 0.958 ± 0.028	1.305HisPro: 1.305 ± 0.032	1.408HisGln: 1.408 ± 0.037	1.236HisArg: 1.236 ± 0.031	1.583HisSer: 1.583 ± 0.038	1.137HisThr: 1.137 ± 0.03	1.285HisVal: 1.285 ± 0.033	0.448HisTrp: 0.448 ± 0.017	1.093HisTyr: 1.093 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	6.222IleAla: 6.222 ± 0.08	0.819IleCys: 0.819 ± 0.026	4.073IleAsp: 4.073 ± 0.06	4.26IleGlu: 4.26 ± 0.062	2.693IlePhe: 2.693 ± 0.056	4.871IleGly: 4.871 ± 0.071	1.525IleHis: 1.525 ± 0.037	4.567IleIle: 4.567 ± 0.083	3.652IleLys: 3.652 ± 0.066	6.091IleLeu: 6.091 ± 0.08	1.593IleMet: 1.593 ± 0.036	3.542IleAsn: 3.542 ± 0.067	3.194IlePro: 3.194 ± 0.045	2.495IleGln: 2.495 ± 0.05	3.462IleArg: 3.462 ± 0.05	5.122IleSer: 5.122 ± 0.072	4.129IleThr: 4.129 ± 0.066	3.926IleVal: 3.926 ± 0.059	0.831IleTrp: 0.831 ± 0.028	2.064IleTyr: 2.064 ± 0.042	0.0IleXaa: 0.0 ± 0.0
Lys	4.215LysAla: 4.215 ± 0.071	0.351LysCys: 0.351 ± 0.017	2.465LysAsp: 2.465 ± 0.052	3.431LysGlu: 3.431 ± 0.07	1.548LysPhe: 1.548 ± 0.038	3.346LysGly: 3.346 ± 0.061	1.167LysHis: 1.167 ± 0.03	3.624LysIle: 3.624 ± 0.062	3.423LysLys: 3.423 ± 0.077	5.27LysLeu: 5.27 ± 0.075	1.545LysMet: 1.545 ± 0.036	2.931LysAsn: 2.931 ± 0.059	2.236LysPro: 2.236 ± 0.043	2.596LysGln: 2.596 ± 0.051	2.73LysArg: 2.73 ± 0.052	3.145LysSer: 3.145 ± 0.05	3.146LysThr: 3.146 ± 0.055	3.223LysVal: 3.223 ± 0.058	0.597LysTrp: 0.597 ± 0.021	1.627LysTyr: 1.627 ± 0.038	0.0LysXaa: 0.0 ± 0.0
Leu	9.178LeuAla: 9.178 ± 0.126	1.223LeuCys: 1.223 ± 0.025	5.32LeuAsp: 5.32 ± 0.071	5.783LeuGlu: 5.783 ± 0.077	4.473LeuPhe: 4.473 ± 0.065	6.585LeuGly: 6.585 ± 0.077	2.345LeuHis: 2.345 ± 0.044	6.629LeuIle: 6.629 ± 0.086	5.33LeuLys: 5.33 ± 0.071	11.114LeuLeu: 11.114 ± 0.125	2.731LeuMet: 2.731 ± 0.052	4.977LeuAsn: 4.977 ± 0.065	5.519LeuPro: 5.519 ± 0.079	4.033LeuGln: 4.033 ± 0.063	5.34LeuArg: 5.34 ± 0.069	8.242LeuSer: 8.242 ± 0.098	6.044LeuThr: 6.044 ± 0.079	6.057LeuVal: 6.057 ± 0.072	1.199LeuTrp: 1.199 ± 0.034	2.924LeuTyr: 2.924 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	2.563MetAla: 2.563 ± 0.048	0.208MetCys: 0.208 ± 0.015	1.216MetAsp: 1.216 ± 0.029	1.449MetGlu: 1.449 ± 0.037	0.87MetPhe: 0.87 ± 0.026	1.758MetGly: 1.758 ± 0.039	0.489MetHis: 0.489 ± 0.02	1.601MetIle: 1.601 ± 0.042	1.602MetLys: 1.602 ± 0.038	2.871MetLeu: 2.871 ± 0.049	0.83MetMet: 0.83 ± 0.027	1.218MetAsn: 1.218 ± 0.031	1.269MetPro: 1.269 ± 0.033	1.102MetGln: 1.102 ± 0.029	1.283MetArg: 1.283 ± 0.033	1.843MetSer: 1.843 ± 0.04	1.641MetThr: 1.641 ± 0.04	1.655MetVal: 1.655 ± 0.035	0.238MetTrp: 0.238 ± 0.014	0.553MetTyr: 0.553 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	3.5AsnAla: 3.5 ± 0.061	0.43AsnCys: 0.43 ± 0.016	2.377AsnAsp: 2.377 ± 0.044	2.68AsnGlu: 2.68 ± 0.047	1.604AsnPhe: 1.604 ± 0.039	3.265AsnGly: 3.265 ± 0.063	1.186AsnHis: 1.186 ± 0.032	3.454AsnIle: 3.454 ± 0.063	2.598AsnLys: 2.598 ± 0.058	4.005AsnLeu: 4.005 ± 0.048	1.145AsnMet: 1.145 ± 0.029	2.492AsnAsn: 2.492 ± 0.055	2.161AsnPro: 2.161 ± 0.041	2.183AsnGln: 2.183 ± 0.046	2.267AsnArg: 2.267 ± 0.041	2.692AsnSer: 2.692 ± 0.05	2.471AsnThr: 2.471 ± 0.053	2.582AsnVal: 2.582 ± 0.055	0.625AsnTrp: 0.625 ± 0.022	1.592AsnTyr: 1.592 ± 0.036	0.0AsnXaa: 0.0 ± 0.0
Pro	3.553ProAla: 3.553 ± 0.068	0.395ProCys: 0.395 ± 0.019	2.956ProAsp: 2.956 ± 0.061	3.652ProGlu: 3.652 ± 0.05	1.801ProPhe: 1.801 ± 0.042	2.361ProGly: 2.361 ± 0.045	1.016ProHis: 1.016 ± 0.028	2.614ProIle: 2.614 ± 0.049	1.953ProLys: 1.953 ± 0.041	4.62ProLeu: 4.62 ± 0.07	1.047ProMet: 1.047 ± 0.033	1.67ProAsn: 1.67 ± 0.037	1.537ProPro: 1.537 ± 0.037	1.838ProGln: 1.838 ± 0.042	1.585ProArg: 1.585 ± 0.039	2.427ProSer: 2.427 ± 0.041	2.101ProThr: 2.101 ± 0.038	3.36ProVal: 3.36 ± 0.052	0.598ProTrp: 0.598 ± 0.021	1.369ProTyr: 1.369 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	3.939GlnAla: 3.939 ± 0.062	0.484GlnCys: 0.484 ± 0.02	1.955GlnAsp: 1.955 ± 0.043	2.473GlnGlu: 2.473 ± 0.047	1.656GlnPhe: 1.656 ± 0.032	3.023GlnGly: 3.023 ± 0.054	1.287GlnHis: 1.287 ± 0.035	2.823GlnIle: 2.823 ± 0.048	2.411GlnLys: 2.411 ± 0.052	5.15GlnLeu: 5.15 ± 0.083	1.071GlnMet: 1.071 ± 0.027	1.766GlnAsn: 1.766 ± 0.037	1.984GlnPro: 1.984 ± 0.048	3.153GlnGln: 3.153 ± 0.065	2.636GlnArg: 2.636 ± 0.05	2.688GlnSer: 2.688 ± 0.046	2.161GlnThr: 2.161 ± 0.044	2.832GlnVal: 2.832 ± 0.049	0.749GlnTrp: 0.749 ± 0.026	1.441GlnTyr: 1.441 ± 0.034	0.0GlnXaa: 0.0 ± 0.0
Arg	3.39ArgAla: 3.39 ± 0.052	0.537ArgCys: 0.537 ± 0.019	2.504ArgAsp: 2.504 ± 0.048	3.286ArgGlu: 3.286 ± 0.056	2.364ArgPhe: 2.364 ± 0.045	2.884ArgGly: 2.884 ± 0.049	1.585ArgHis: 1.585 ± 0.038	3.483ArgIle: 3.483 ± 0.05	2.574ArgLys: 2.574 ± 0.045	5.782ArgLeu: 5.782 ± 0.083	1.363ArgMet: 1.363 ± 0.034	2.266ArgAsn: 2.266 ± 0.042	1.97ArgPro: 1.97 ± 0.044	2.827ArgGln: 2.827 ± 0.055	2.843ArgArg: 2.843 ± 0.056	2.706ArgSer: 2.706 ± 0.053	2.345ArgThr: 2.345 ± 0.04	3.045ArgVal: 3.045 ± 0.05	0.792ArgTrp: 0.792 ± 0.024	2.117ArgTyr: 2.117 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	5.14SerAla: 5.14 ± 0.078	0.657SerCys: 0.657 ± 0.022	3.437SerAsp: 3.437 ± 0.051	3.827SerGlu: 3.827 ± 0.059	2.65SerPhe: 2.65 ± 0.044	5.29SerGly: 5.29 ± 0.067	1.787SerHis: 1.787 ± 0.041	4.173SerIle: 4.173 ± 0.067	2.724SerLys: 2.724 ± 0.054	7.287SerLeu: 7.287 ± 0.078	1.635SerMet: 1.635 ± 0.038	2.414SerAsn: 2.414 ± 0.042	2.948SerPro: 2.948 ± 0.048	3.01SerGln: 3.01 ± 0.063	3.272SerArg: 3.272 ± 0.052	4.206SerSer: 4.206 ± 0.076	3.101SerThr: 3.101 ± 0.051	4.286SerVal: 4.286 ± 0.065	0.929SerTrp: 0.929 ± 0.026	2.029SerTyr: 2.029 ± 0.046	0.0SerXaa: 0.0 ± 0.0
Thr	4.265ThrAla: 4.265 ± 0.072	0.51ThrCys: 0.51 ± 0.021	2.692ThrAsp: 2.692 ± 0.047	3.231ThrGlu: 3.231 ± 0.051	2.019ThrPhe: 2.019 ± 0.042	4.074ThrGly: 4.074 ± 0.067	1.326ThrHis: 1.326 ± 0.033	3.329ThrIle: 3.329 ± 0.058	2.136ThrLys: 2.136 ± 0.05	6.674ThrLeu: 6.674 ± 0.096	1.11ThrMet: 1.11 ± 0.03	1.844ThrAsn: 1.844 ± 0.035	2.956ThrPro: 2.956 ± 0.052	2.393ThrGln: 2.393 ± 0.045	2.507ThrArg: 2.507 ± 0.038	3.108ThrSer: 3.108 ± 0.051	2.809ThrThr: 2.809 ± 0.056	3.65ThrVal: 3.65 ± 0.056	0.581ThrTrp: 0.581 ± 0.02	1.509ThrTyr: 1.509 ± 0.039	0.0ThrXaa: 0.0 ± 0.0
Val	5.113ValAla: 5.113 ± 0.076	0.708ValCys: 0.708 ± 0.025	3.332ValAsp: 3.332 ± 0.055	3.624ValGlu: 3.624 ± 0.058	2.546ValPhe: 2.546 ± 0.049	4.169ValGly: 4.169 ± 0.072	1.225ValHis: 1.225 ± 0.035	4.8ValIle: 4.8 ± 0.066	3.234ValLys: 3.234 ± 0.059	6.132ValLeu: 6.132 ± 0.087	1.908ValMet: 1.908 ± 0.044	2.821ValAsn: 2.821 ± 0.047	2.544ValPro: 2.544 ± 0.042	2.166ValGln: 2.166 ± 0.044	2.967ValArg: 2.967 ± 0.054	4.444ValSer: 4.444 ± 0.061	3.683ValThr: 3.683 ± 0.067	4.223ValVal: 4.223 ± 0.068	0.784ValTrp: 0.784 ± 0.025	1.754ValTyr: 1.754 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	0.853TrpAla: 0.853 ± 0.027	0.165TrpCys: 0.165 ± 0.011	0.656TrpAsp: 0.656 ± 0.024	0.689TrpGlu: 0.689 ± 0.022	0.603TrpPhe: 0.603 ± 0.02	0.85TrpGly: 0.85 ± 0.025	0.43TrpHis: 0.43 ± 0.019	0.746TrpIle: 0.746 ± 0.024	0.664TrpLys: 0.664 ± 0.022	1.942TrpLeu: 1.942 ± 0.038	0.355TrpMet: 0.355 ± 0.016	0.55TrpAsn: 0.55 ± 0.022	0.562TrpPro: 0.562 ± 0.018	1.064TrpGln: 1.064 ± 0.03	0.869TrpArg: 0.869 ± 0.024	0.814TrpSer: 0.814 ± 0.024	0.475TrpThr: 0.475 ± 0.019	0.824TrpVal: 0.824 ± 0.026	0.193TrpTrp: 0.193 ± 0.011	0.375TrpTyr: 0.375 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.312TyrAla: 2.312 ± 0.045	0.439TyrCys: 0.439 ± 0.016	1.717TyrAsp: 1.717 ± 0.047	1.52TyrGlu: 1.52 ± 0.039	1.539TyrPhe: 1.539 ± 0.035	2.289TyrGly: 2.289 ± 0.043	1.005TyrHis: 1.005 ± 0.026	1.981TyrIle: 1.981 ± 0.041	1.291TyrLys: 1.291 ± 0.038	3.612TyrLeu: 3.612 ± 0.053	0.697TyrMet: 0.697 ± 0.023	1.282TyrAsn: 1.282 ± 0.038	1.575TyrPro: 1.575 ± 0.037	1.902TyrGln: 1.902 ± 0.037	2.047TyrArg: 2.047 ± 0.044	2.179TyrSer: 2.179 ± 0.047	1.621TyrThr: 1.621 ± 0.038	1.705TyrVal: 1.705 ± 0.035	0.518TyrTrp: 0.518 ± 0.02	1.148TyrTyr: 1.148 ± 0.034	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4565 proteins (1315782 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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