Amino acid dipepetide frequency for Flavisolibacter ginsenosidimutans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.748AlaAla: 7.748 ± 0.095	0.806AlaCys: 0.806 ± 0.025	4.256AlaAsp: 4.256 ± 0.051	4.525AlaGlu: 4.525 ± 0.074	3.98AlaPhe: 3.98 ± 0.058	6.035AlaGly: 6.035 ± 0.074	1.367AlaHis: 1.367 ± 0.03	4.689AlaIle: 4.689 ± 0.069	5.257AlaLys: 5.257 ± 0.068	7.403AlaLeu: 7.403 ± 0.087	1.789AlaMet: 1.789 ± 0.039	3.873AlaAsn: 3.873 ± 0.061	2.617AlaPro: 2.617 ± 0.052	3.326AlaGln: 3.326 ± 0.056	2.722AlaArg: 2.722 ± 0.04	5.215AlaSer: 5.215 ± 0.068	4.823AlaThr: 4.823 ± 0.083	6.017AlaVal: 6.017 ± 0.067	0.937AlaTrp: 0.937 ± 0.026	3.038AlaTyr: 3.038 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	0.639CysAla: 0.639 ± 0.023	0.16CysCys: 0.16 ± 0.012	0.428CysAsp: 0.428 ± 0.021	0.463CysGlu: 0.463 ± 0.02	0.564CysPhe: 0.564 ± 0.017	0.758CysGly: 0.758 ± 0.027	0.209CysHis: 0.209 ± 0.013	0.586CysIle: 0.586 ± 0.023	0.541CysLys: 0.541 ± 0.02	0.903CysLeu: 0.903 ± 0.026	0.176CysMet: 0.176 ± 0.011	0.439CysAsn: 0.439 ± 0.018	0.375CysPro: 0.375 ± 0.018	0.248CysGln: 0.248 ± 0.013	0.411CysArg: 0.411 ± 0.017	0.582CysSer: 0.582 ± 0.021	0.548CysThr: 0.548 ± 0.024	0.6CysVal: 0.6 ± 0.021	0.105CysTrp: 0.105 ± 0.008	0.313CysTyr: 0.313 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	4.602AspAla: 4.602 ± 0.062	0.435AspCys: 0.435 ± 0.019	2.537AspAsp: 2.537 ± 0.046	3.583AspGlu: 3.583 ± 0.059	2.786AspPhe: 2.786 ± 0.045	3.935AspGly: 3.935 ± 0.063	0.817AspHis: 0.817 ± 0.025	2.928AspIle: 2.928 ± 0.052	3.581AspLys: 3.581 ± 0.052	4.625AspLeu: 4.625 ± 0.067	0.992AspMet: 0.992 ± 0.029	2.396AspAsn: 2.396 ± 0.045	1.921AspPro: 1.921 ± 0.04	1.24AspGln: 1.24 ± 0.03	1.998AspArg: 1.998 ± 0.035	3.008AspSer: 3.008 ± 0.058	2.425AspThr: 2.425 ± 0.05	4.109AspVal: 4.109 ± 0.051	0.818AspTrp: 0.818 ± 0.024	2.57AspTyr: 2.57 ± 0.049	0.0AspXaa: 0.0 ± 0.0
Glu	4.909GluAla: 4.909 ± 0.072	0.366GluCys: 0.366 ± 0.018	2.68GluAsp: 2.68 ± 0.047	4.315GluGlu: 4.315 ± 0.079	2.232GluPhe: 2.232 ± 0.044	3.789GluGly: 3.789 ± 0.057	1.064GluHis: 1.064 ± 0.028	3.756GluIle: 3.756 ± 0.065	5.104GluLys: 5.104 ± 0.073	5.293GluLeu: 5.293 ± 0.071	1.47GluMet: 1.47 ± 0.033	3.026GluAsn: 3.026 ± 0.048	1.767GluPro: 1.767 ± 0.038	2.341GluGln: 2.341 ± 0.039	2.826GluArg: 2.826 ± 0.052	2.729GluSer: 2.729 ± 0.046	3.11GluThr: 3.11 ± 0.047	3.625GluVal: 3.625 ± 0.057	0.8GluTrp: 0.8 ± 0.027	1.838GluTyr: 1.838 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	3.944PheAla: 3.944 ± 0.058	0.57PheCys: 0.57 ± 0.02	2.842PheAsp: 2.842 ± 0.04	2.542PheGlu: 2.542 ± 0.042	2.827PhePhe: 2.827 ± 0.058	3.613PheGly: 3.613 ± 0.059	0.927PheHis: 0.927 ± 0.026	2.992PheIle: 2.992 ± 0.048	2.687PheLys: 2.687 ± 0.041	4.944PheLeu: 4.944 ± 0.081	0.925PheMet: 0.925 ± 0.029	2.602PheAsn: 2.602 ± 0.05	1.795PhePro: 1.795 ± 0.036	1.587PheGln: 1.587 ± 0.033	1.955PheArg: 1.955 ± 0.037	3.96PheSer: 3.96 ± 0.058	3.145PheThr: 3.145 ± 0.052	3.471PheVal: 3.471 ± 0.054	0.611PheTrp: 0.611 ± 0.021	2.101PheTyr: 2.101 ± 0.04	0.0PheXaa: 0.0 ± 0.0
Gly	5.128GlyAla: 5.128 ± 0.068	0.802GlyCys: 0.802 ± 0.04	3.473GlyAsp: 3.473 ± 0.055	3.742GlyGlu: 3.742 ± 0.052	3.642GlyPhe: 3.642 ± 0.048	5.528GlyGly: 5.528 ± 0.088	1.265GlyHis: 1.265 ± 0.028	4.702GlyIle: 4.702 ± 0.062	5.228GlyLys: 5.228 ± 0.071	6.306GlyLeu: 6.306 ± 0.066	1.612GlyMet: 1.612 ± 0.036	3.753GlyAsn: 3.753 ± 0.068	1.711GlyPro: 1.711 ± 0.038	2.343GlyGln: 2.343 ± 0.046	2.937GlyArg: 2.937 ± 0.049	4.553GlySer: 4.553 ± 0.065	4.504GlyThr: 4.504 ± 0.081	4.708GlyVal: 4.708 ± 0.066	1.1GlyTrp: 1.1 ± 0.027	3.091GlyTyr: 3.091 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	1.239HisAla: 1.239 ± 0.034	0.259HisCys: 0.259 ± 0.012	0.898HisAsp: 0.898 ± 0.02	0.968HisGlu: 0.968 ± 0.026	1.213HisPhe: 1.213 ± 0.033	1.251HisGly: 1.251 ± 0.03	0.586HisHis: 0.586 ± 0.023	1.137HisIle: 1.137 ± 0.028	1.055HisLys: 1.055 ± 0.029	1.95HisLeu: 1.95 ± 0.038	0.354HisMet: 0.354 ± 0.016	0.92HisAsn: 0.92 ± 0.027	1.163HisPro: 1.163 ± 0.031	0.749HisGln: 0.749 ± 0.02	0.89HisArg: 0.89 ± 0.027	1.113HisSer: 1.113 ± 0.025	1.032HisThr: 1.032 ± 0.03	1.089HisVal: 1.089 ± 0.028	0.293HisTrp: 0.293 ± 0.014	0.897HisTyr: 0.897 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.228IleAla: 5.228 ± 0.063	0.577IleCys: 0.577 ± 0.023	3.453IleAsp: 3.453 ± 0.047	3.778IleGlu: 3.778 ± 0.06	2.635IlePhe: 2.635 ± 0.045	4.407IleGly: 4.407 ± 0.063	1.131IleHis: 1.131 ± 0.032	3.621IleIle: 3.621 ± 0.063	4.043IleLys: 4.043 ± 0.06	5.099IleLeu: 5.099 ± 0.068	1.007IleMet: 1.007 ± 0.025	3.365IleAsn: 3.365 ± 0.045	2.664IlePro: 2.664 ± 0.042	2.017IleGln: 2.017 ± 0.037	2.655IleArg: 2.655 ± 0.046	3.848IleSer: 3.848 ± 0.051	3.845IleThr: 3.845 ± 0.06	4.236IleVal: 4.236 ± 0.059	0.646IleTrp: 0.646 ± 0.02	2.074IleTyr: 2.074 ± 0.04	0.0IleXaa: 0.0 ± 0.0
Lys	5.775LysAla: 5.775 ± 0.068	0.363LysCys: 0.363 ± 0.016	4.005LysAsp: 4.005 ± 0.062	5.438LysGlu: 5.438 ± 0.081	2.448LysPhe: 2.448 ± 0.047	4.793LysGly: 4.793 ± 0.062	1.21LysHis: 1.21 ± 0.031	4.406LysIle: 4.406 ± 0.057	5.75LysLys: 5.75 ± 0.076	5.599LysLeu: 5.599 ± 0.062	1.749LysMet: 1.749 ± 0.043	3.93LysAsn: 3.93 ± 0.046	2.929LysPro: 2.929 ± 0.05	2.765LysGln: 2.765 ± 0.047	3.022LysArg: 3.022 ± 0.043	3.447LysSer: 3.447 ± 0.046	4.282LysThr: 4.282 ± 0.061	4.074LysVal: 4.074 ± 0.054	0.79LysTrp: 0.79 ± 0.023	2.357LysTyr: 2.357 ± 0.044	0.0LysXaa: 0.0 ± 0.0
Leu	7.023LeuAla: 7.023 ± 0.08	0.972LeuCys: 0.972 ± 0.026	4.241LeuAsp: 4.241 ± 0.058	4.458LeuGlu: 4.458 ± 0.061	5.16LeuPhe: 5.16 ± 0.081	5.512LeuGly: 5.512 ± 0.072	2.115LeuHis: 2.115 ± 0.043	5.076LeuIle: 5.076 ± 0.065	6.512LeuLys: 6.512 ± 0.069	10.314LeuLeu: 10.314 ± 0.132	2.038LeuMet: 2.038 ± 0.035	4.985LeuAsn: 4.985 ± 0.065	4.486LeuPro: 4.486 ± 0.054	4.722LeuGln: 4.722 ± 0.073	4.325LeuArg: 4.325 ± 0.07	6.977LeuSer: 6.977 ± 0.076	5.345LeuThr: 5.345 ± 0.063	5.74LeuVal: 5.74 ± 0.065	1.071LeuTrp: 1.071 ± 0.029	3.345LeuTyr: 3.345 ± 0.061	0.0LeuXaa: 0.0 ± 0.0
Met	1.764MetAla: 1.764 ± 0.037	0.139MetCys: 0.139 ± 0.01	1.059MetAsp: 1.059 ± 0.029	1.241MetGlu: 1.241 ± 0.03	0.743MetPhe: 0.743 ± 0.022	1.293MetGly: 1.293 ± 0.035	0.417MetHis: 0.417 ± 0.016	1.263MetIle: 1.263 ± 0.03	2.11MetLys: 2.11 ± 0.042	1.843MetLeu: 1.843 ± 0.036	0.609MetMet: 0.609 ± 0.022	1.343MetAsn: 1.343 ± 0.028	1.037MetPro: 1.037 ± 0.025	1.085MetGln: 1.085 ± 0.023	1.05MetArg: 1.05 ± 0.029	1.159MetSer: 1.159 ± 0.029	1.163MetThr: 1.163 ± 0.029	1.238MetVal: 1.238 ± 0.031	0.203MetTrp: 0.203 ± 0.012	0.591MetTyr: 0.591 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	4.305AsnAla: 4.305 ± 0.063	0.468AsnCys: 0.468 ± 0.021	2.867AsnAsp: 2.867 ± 0.047	3.036AsnGlu: 3.036 ± 0.05	2.559AsnPhe: 2.559 ± 0.057	4.423AsnGly: 4.423 ± 0.06	0.951AsnHis: 0.951 ± 0.024	3.369AsnIle: 3.369 ± 0.044	3.251AsnLys: 3.251 ± 0.042	4.803AsnLeu: 4.803 ± 0.055	0.971AsnMet: 0.971 ± 0.026	3.169AsnAsn: 3.169 ± 0.061	2.644AsnPro: 2.644 ± 0.046	1.614AsnGln: 1.614 ± 0.037	2.35AsnArg: 2.35 ± 0.045	2.953AsnSer: 2.953 ± 0.053	3.163AsnThr: 3.163 ± 0.055	3.599AsnVal: 3.599 ± 0.056	0.745AsnTrp: 0.745 ± 0.022	2.345AsnTyr: 2.345 ± 0.041	0.0AsnXaa: 0.0 ± 0.0
Pro	3.474ProAla: 3.474 ± 0.056	0.237ProCys: 0.237 ± 0.013	2.408ProAsp: 2.408 ± 0.044	2.466ProGlu: 2.466 ± 0.045	2.121ProPhe: 2.121 ± 0.043	2.718ProGly: 2.718 ± 0.044	0.788ProHis: 0.788 ± 0.024	1.865ProIle: 1.865 ± 0.042	2.305ProLys: 2.305 ± 0.039	3.756ProLeu: 3.756 ± 0.057	0.73ProMet: 0.73 ± 0.022	1.988ProAsn: 1.988 ± 0.042	1.314ProPro: 1.314 ± 0.035	1.785ProGln: 1.785 ± 0.036	1.245ProArg: 1.245 ± 0.025	2.716ProSer: 2.716 ± 0.046	2.229ProThr: 2.229 ± 0.043	3.535ProVal: 3.535 ± 0.047	0.495ProTrp: 0.495 ± 0.02	1.605ProTyr: 1.605 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	2.796GlnAla: 2.796 ± 0.043	0.267GlnCys: 0.267 ± 0.014	1.459GlnAsp: 1.459 ± 0.031	1.87GlnGlu: 1.87 ± 0.038	1.709GlnPhe: 1.709 ± 0.036	2.097GlnGly: 2.097 ± 0.033	0.834GlnHis: 0.834 ± 0.023	2.27GlnIle: 2.27 ± 0.038	3.169GlnLys: 3.169 ± 0.047	3.821GlnLeu: 3.821 ± 0.049	0.959GlnMet: 0.959 ± 0.023	2.259GlnAsn: 2.259 ± 0.041	1.695GlnPro: 1.695 ± 0.035	2.137GlnGln: 2.137 ± 0.045	1.931GlnArg: 1.931 ± 0.036	2.397GlnSer: 2.397 ± 0.045	2.599GlnThr: 2.599 ± 0.046	2.178GlnVal: 2.178 ± 0.04	0.585GlnTrp: 0.585 ± 0.022	1.542GlnTyr: 1.542 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	2.47ArgAla: 2.47 ± 0.043	0.327ArgCys: 0.327 ± 0.015	2.031ArgAsp: 2.031 ± 0.037	2.377ArgGlu: 2.377 ± 0.045	2.415ArgPhe: 2.415 ± 0.043	2.422ArgGly: 2.422 ± 0.046	0.779ArgHis: 0.779 ± 0.027	3.205ArgIle: 3.205 ± 0.05	3.132ArgLys: 3.132 ± 0.049	4.279ArgLeu: 4.279 ± 0.053	1.213ArgMet: 1.213 ± 0.031	2.4ArgAsn: 2.4 ± 0.042	1.519ArgPro: 1.519 ± 0.034	1.692ArgGln: 1.692 ± 0.038	2.074ArgArg: 2.074 ± 0.043	2.54ArgSer: 2.54 ± 0.044	2.384ArgThr: 2.384 ± 0.042	2.453ArgVal: 2.453 ± 0.044	0.671ArgTrp: 0.671 ± 0.024	1.935ArgTyr: 1.935 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	4.95SerAla: 4.95 ± 0.061	0.628SerCys: 0.628 ± 0.02	2.983SerAsp: 2.983 ± 0.051	2.886SerGlu: 2.886 ± 0.049	3.941SerPhe: 3.941 ± 0.059	5.119SerGly: 5.119 ± 0.081	1.086SerHis: 1.086 ± 0.028	3.862SerIle: 3.862 ± 0.047	3.611SerLys: 3.611 ± 0.051	6.606SerLeu: 6.606 ± 0.078	1.201SerMet: 1.201 ± 0.027	3.179SerAsn: 3.179 ± 0.054	2.545SerPro: 2.545 ± 0.05	2.112SerGln: 2.112 ± 0.041	2.484SerArg: 2.484 ± 0.041	4.408SerSer: 4.408 ± 0.074	3.809SerThr: 3.809 ± 0.072	4.567SerVal: 4.567 ± 0.068	0.828SerTrp: 0.828 ± 0.021	2.45SerTyr: 2.45 ± 0.044	0.0SerXaa: 0.0 ± 0.0
Thr	5.485ThrAla: 5.485 ± 0.082	0.437ThrCys: 0.437 ± 0.021	3.195ThrAsp: 3.195 ± 0.055	3.073ThrGlu: 3.073 ± 0.057	2.755ThrPhe: 2.755 ± 0.048	4.814ThrGly: 4.814 ± 0.071	1.066ThrHis: 1.066 ± 0.028	3.656ThrIle: 3.656 ± 0.055	3.705ThrLys: 3.705 ± 0.052	5.351ThrLeu: 5.351 ± 0.062	0.968ThrMet: 0.968 ± 0.028	2.906ThrAsn: 2.906 ± 0.059	2.759ThrPro: 2.759 ± 0.045	1.942ThrGln: 1.942 ± 0.037	1.901ThrArg: 1.901 ± 0.037	3.654ThrSer: 3.654 ± 0.072	4.09ThrThr: 4.09 ± 0.082	4.837ThrVal: 4.837 ± 0.088	0.76ThrTrp: 0.76 ± 0.026	2.237ThrTyr: 2.237 ± 0.051	0.0ThrXaa: 0.0 ± 0.0
Val	5.207ValAla: 5.207 ± 0.074	0.743ValCys: 0.743 ± 0.025	3.617ValAsp: 3.617 ± 0.051	3.636ValGlu: 3.636 ± 0.053	3.452ValPhe: 3.452 ± 0.049	3.987ValGly: 3.987 ± 0.059	1.344ValHis: 1.344 ± 0.033	4.128ValIle: 4.128 ± 0.052	4.569ValLys: 4.569 ± 0.063	6.496ValLeu: 6.496 ± 0.066	1.518ValMet: 1.518 ± 0.035	3.761ValAsn: 3.761 ± 0.055	2.779ValPro: 2.779 ± 0.051	2.712ValGln: 2.712 ± 0.044	2.879ValArg: 2.879 ± 0.042	4.675ValSer: 4.675 ± 0.061	3.98ValThr: 3.98 ± 0.077	5.015ValVal: 5.015 ± 0.075	0.859ValTrp: 0.859 ± 0.024	2.78ValTyr: 2.78 ± 0.046	0.0ValXaa: 0.0 ± 0.0
Trp	0.835TrpAla: 0.835 ± 0.026	0.12TrpCys: 0.12 ± 0.009	0.694TrpAsp: 0.694 ± 0.021	0.665TrpGlu: 0.665 ± 0.022	0.646TrpPhe: 0.646 ± 0.024	0.882TrpGly: 0.882 ± 0.024	0.294TrpHis: 0.294 ± 0.014	0.782TrpIle: 0.782 ± 0.022	0.994TrpLys: 0.994 ± 0.027	1.284TrpLeu: 1.284 ± 0.031	0.393TrpMet: 0.393 ± 0.016	0.863TrpAsn: 0.863 ± 0.027	0.394TrpPro: 0.394 ± 0.02	0.64TrpGln: 0.64 ± 0.022	0.629TrpArg: 0.629 ± 0.023	0.794TrpSer: 0.794 ± 0.024	0.735TrpThr: 0.735 ± 0.023	0.729TrpVal: 0.729 ± 0.022	0.252TrpTrp: 0.252 ± 0.015	0.489TrpTyr: 0.489 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.903TyrAla: 2.903 ± 0.041	0.372TyrCys: 0.372 ± 0.016	2.18TyrAsp: 2.18 ± 0.046	1.98TyrGlu: 1.98 ± 0.04	2.211TyrPhe: 2.211 ± 0.04	2.754TyrGly: 2.754 ± 0.048	0.805TyrHis: 0.805 ± 0.024	2.038TyrIle: 2.038 ± 0.037	2.527TyrLys: 2.527 ± 0.042	3.741TyrLeu: 3.741 ± 0.053	0.672TyrMet: 0.672 ± 0.022	2.427TyrAsn: 2.427 ± 0.044	1.667TyrPro: 1.667 ± 0.036	1.516TyrGln: 1.516 ± 0.033	2.034TyrArg: 2.034 ± 0.041	2.529TyrSer: 2.529 ± 0.038	2.382TyrThr: 2.382 ± 0.046	2.317TyrVal: 2.317 ± 0.04	0.545TyrTrp: 0.545 ± 0.021	1.767TyrTyr: 1.767 ± 0.038	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4236 proteins (1490540 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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