Amino acid dipepetide frequency for Pigeon adenovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.98AlaAla: 11.98 ± 1.241
1.607AlaCys: 1.607 ± 0.282
4.675AlaAsp: 4.675 ± 0.592
5.771AlaGlu: 5.771 ± 0.82
2.265AlaPhe: 2.265 ± 0.471
5.698AlaGly: 5.698 ± 0.989
1.607AlaHis: 1.607 ± 0.422
2.922AlaIle: 2.922 ± 0.558
1.753AlaLys: 1.753 ± 0.27
9.351AlaLeu: 9.351 ± 1.115
1.68AlaMet: 1.68 ± 0.477
2.63AlaAsn: 2.63 ± 0.504
6.355AlaPro: 6.355 ± 0.775
3.653AlaGln: 3.653 ± 0.576
5.844AlaArg: 5.844 ± 0.842
5.625AlaSer: 5.625 ± 0.651
5.625AlaThr: 5.625 ± 0.932
6.867AlaVal: 6.867 ± 0.614
1.242AlaTrp: 1.242 ± 0.284
3.58AlaTyr: 3.58 ± 0.454
0.0AlaXaa: 0.0 ± 0.0
Cys
1.315CysAla: 1.315 ± 0.293
0.073CysCys: 0.073 ± 0.077
0.804CysAsp: 0.804 ± 0.251
0.877CysGlu: 0.877 ± 0.276
1.169CysPhe: 1.169 ± 0.325
1.096CysGly: 1.096 ± 0.274
0.804CysHis: 0.804 ± 0.262
0.438CysIle: 0.438 ± 0.195
0.731CysLys: 0.731 ± 0.173
1.534CysLeu: 1.534 ± 0.368
0.365CysMet: 0.365 ± 0.184
0.804CysAsn: 0.804 ± 0.226
1.169CysPro: 1.169 ± 0.264
1.023CysGln: 1.023 ± 0.248
1.388CysArg: 1.388 ± 0.385
1.023CysSer: 1.023 ± 0.283
1.534CysThr: 1.534 ± 0.412
1.023CysVal: 1.023 ± 0.268
0.292CysTrp: 0.292 ± 0.14
0.731CysTyr: 0.731 ± 0.259
0.0CysXaa: 0.0 ± 0.0
Asp
5.479AspAla: 5.479 ± 0.856
0.657AspCys: 0.657 ± 0.222
3.36AspAsp: 3.36 ± 0.507
4.091AspGlu: 4.091 ± 0.677
2.118AspPhe: 2.118 ± 0.391
4.237AspGly: 4.237 ± 0.472
1.096AspHis: 1.096 ± 0.249
1.461AspIle: 1.461 ± 0.391
1.023AspLys: 1.023 ± 0.232
5.625AspLeu: 5.625 ± 0.405
0.731AspMet: 0.731 ± 0.245
2.338AspAsn: 2.338 ± 0.516
4.675AspPro: 4.675 ± 0.715
1.388AspGln: 1.388 ± 0.261
3.945AspArg: 3.945 ± 0.702
2.776AspSer: 2.776 ± 0.502
3.141AspThr: 3.141 ± 0.506
3.726AspVal: 3.726 ± 0.548
0.584AspTrp: 0.584 ± 0.192
1.534AspTyr: 1.534 ± 0.305
0.0AspXaa: 0.0 ± 0.0
Glu
4.31GluAla: 4.31 ± 0.678
0.584GluCys: 0.584 ± 0.197
4.091GluAsp: 4.091 ± 0.738
8.036GluGlu: 8.036 ± 1.816
1.169GluPhe: 1.169 ± 0.3
4.018GluGly: 4.018 ± 0.653
1.607GluHis: 1.607 ± 0.355
1.461GluIle: 1.461 ± 0.386
1.461GluLys: 1.461 ± 0.252
5.26GluLeu: 5.26 ± 0.429
0.95GluMet: 0.95 ± 0.344
1.753GluAsn: 1.753 ± 0.334
4.456GluPro: 4.456 ± 0.703
1.972GluGln: 1.972 ± 0.325
5.187GluArg: 5.187 ± 0.648
2.63GluSer: 2.63 ± 0.497
3.506GluThr: 3.506 ± 0.622
2.849GluVal: 2.849 ± 0.667
0.804GluTrp: 0.804 ± 0.168
1.68GluTyr: 1.68 ± 0.331
0.0GluXaa: 0.0 ± 0.0
Phe
2.922PheAla: 2.922 ± 0.611
0.584PheCys: 0.584 ± 0.194
2.703PheAsp: 2.703 ± 0.37
1.899PheGlu: 1.899 ± 0.379
1.972PhePhe: 1.972 ± 0.278
1.096PheGly: 1.096 ± 0.269
1.388PheHis: 1.388 ± 0.338
1.096PheIle: 1.096 ± 0.244
1.023PheLys: 1.023 ± 0.213
4.675PheLeu: 4.675 ± 0.634
0.877PheMet: 0.877 ± 0.247
1.607PheAsn: 1.607 ± 0.401
2.484PhePro: 2.484 ± 0.395
1.242PheGln: 1.242 ± 0.323
3.433PheArg: 3.433 ± 0.543
2.776PheSer: 2.776 ± 0.426
1.753PheThr: 1.753 ± 0.509
3.36PheVal: 3.36 ± 0.524
0.584PheTrp: 0.584 ± 0.195
1.899PheTyr: 1.899 ± 0.379
0.0PheXaa: 0.0 ± 0.0
Gly
6.794GlyAla: 6.794 ± 0.793
0.584GlyCys: 0.584 ± 0.246
2.703GlyAsp: 2.703 ± 0.466
3.653GlyGlu: 3.653 ± 0.682
2.849GlyPhe: 2.849 ± 0.573
7.013GlyGly: 7.013 ± 1.241
1.023GlyHis: 1.023 ± 0.266
1.68GlyIle: 1.68 ± 0.43
1.315GlyLys: 1.315 ± 0.229
4.748GlyLeu: 4.748 ± 0.853
1.315GlyMet: 1.315 ± 0.256
1.899GlyAsn: 1.899 ± 0.389
4.164GlyPro: 4.164 ± 0.519
2.63GlyGln: 2.63 ± 0.495
5.041GlyArg: 5.041 ± 0.71
3.58GlySer: 3.58 ± 0.432
3.799GlyThr: 3.799 ± 0.676
4.675GlyVal: 4.675 ± 0.695
1.169GlyTrp: 1.169 ± 0.295
2.118GlyTyr: 2.118 ± 0.319
0.0GlyXaa: 0.0 ± 0.0
His
2.265HisAla: 2.265 ± 0.373
0.804HisCys: 0.804 ± 0.308
1.096HisAsp: 1.096 ± 0.247
0.731HisGlu: 0.731 ± 0.189
0.95HisPhe: 0.95 ± 0.252
1.388HisGly: 1.388 ± 0.271
1.023HisHis: 1.023 ± 0.347
0.584HisIle: 0.584 ± 0.166
0.584HisLys: 0.584 ± 0.173
2.484HisLeu: 2.484 ± 0.549
0.292HisMet: 0.292 ± 0.157
1.461HisAsn: 1.461 ± 0.29
2.411HisPro: 2.411 ± 0.551
0.877HisGln: 0.877 ± 0.213
2.118HisArg: 2.118 ± 0.376
1.534HisSer: 1.534 ± 0.418
0.95HisThr: 0.95 ± 0.265
1.899HisVal: 1.899 ± 0.45
0.292HisTrp: 0.292 ± 0.141
0.877HisTyr: 0.877 ± 0.199
0.0HisXaa: 0.0 ± 0.0
Ile
2.338IleAla: 2.338 ± 0.454
0.877IleCys: 0.877 ± 0.319
1.534IleAsp: 1.534 ± 0.392
1.023IleGlu: 1.023 ± 0.214
0.657IlePhe: 0.657 ± 0.193
1.534IleGly: 1.534 ± 0.41
0.804IleHis: 0.804 ± 0.212
0.804IleIle: 0.804 ± 0.234
1.023IleLys: 1.023 ± 0.252
2.265IleLeu: 2.265 ± 0.36
0.292IleMet: 0.292 ± 0.147
1.023IleAsn: 1.023 ± 0.377
2.338IlePro: 2.338 ± 0.401
0.95IleGln: 0.95 ± 0.272
1.972IleArg: 1.972 ± 0.33
1.534IleSer: 1.534 ± 0.415
0.95IleThr: 0.95 ± 0.243
1.607IleVal: 1.607 ± 0.358
0.365IleTrp: 0.365 ± 0.154
0.877IleTyr: 0.877 ± 0.198
0.0IleXaa: 0.0 ± 0.0
Lys
1.388LysAla: 1.388 ± 0.373
0.804LysCys: 0.804 ± 0.239
1.169LysAsp: 1.169 ± 0.306
1.023LysGlu: 1.023 ± 0.268
1.169LysPhe: 1.169 ± 0.28
1.753LysGly: 1.753 ± 0.275
0.365LysHis: 0.365 ± 0.139
0.804LysIle: 0.804 ± 0.192
0.731LysLys: 0.731 ± 0.283
2.411LysLeu: 2.411 ± 0.418
0.438LysMet: 0.438 ± 0.177
0.877LysAsn: 0.877 ± 0.247
1.096LysPro: 1.096 ± 0.227
1.169LysGln: 1.169 ± 0.239
2.265LysArg: 2.265 ± 0.33
1.169LysSer: 1.169 ± 0.336
1.753LysThr: 1.753 ± 0.357
1.315LysVal: 1.315 ± 0.269
0.584LysTrp: 0.584 ± 0.291
1.169LysTyr: 1.169 ± 0.298
0.0LysXaa: 0.0 ± 0.0
Leu
8.474LeuAla: 8.474 ± 0.885
2.338LeuCys: 2.338 ± 0.471
5.844LeuAsp: 5.844 ± 0.597
4.456LeuGlu: 4.456 ± 0.612
4.091LeuPhe: 4.091 ± 0.757
4.456LeuGly: 4.456 ± 0.555
2.703LeuHis: 2.703 ± 0.606
1.972LeuIle: 1.972 ± 0.31
2.338LeuLys: 2.338 ± 0.427
10.739LeuLeu: 10.739 ± 1.105
2.411LeuMet: 2.411 ± 0.368
3.287LeuAsn: 3.287 ± 0.403
6.648LeuPro: 6.648 ± 0.738
4.237LeuGln: 4.237 ± 0.582
9.497LeuArg: 9.497 ± 1.079
8.036LeuSer: 8.036 ± 0.804
5.479LeuThr: 5.479 ± 0.58
5.844LeuVal: 5.844 ± 0.808
1.607LeuTrp: 1.607 ± 0.296
4.602LeuTyr: 4.602 ± 0.551
0.0LeuXaa: 0.0 ± 0.0
Met
2.411MetAla: 2.411 ± 0.484
0.438MetCys: 0.438 ± 0.193
0.877MetAsp: 0.877 ± 0.272
0.584MetGlu: 0.584 ± 0.255
0.657MetPhe: 0.657 ± 0.22
1.096MetGly: 1.096 ± 0.24
0.657MetHis: 0.657 ± 0.228
0.804MetIle: 0.804 ± 0.252
0.511MetLys: 0.511 ± 0.207
1.388MetLeu: 1.388 ± 0.29
0.365MetMet: 0.365 ± 0.148
0.584MetAsn: 0.584 ± 0.234
1.242MetPro: 1.242 ± 0.274
0.511MetGln: 0.511 ± 0.158
1.534MetArg: 1.534 ± 0.367
1.242MetSer: 1.242 ± 0.337
1.023MetThr: 1.023 ± 0.281
1.169MetVal: 1.169 ± 0.267
0.292MetTrp: 0.292 ± 0.153
0.95MetTyr: 0.95 ± 0.311
0.0MetXaa: 0.0 ± 0.0
Asn
2.995AsnAla: 2.995 ± 0.661
0.365AsnCys: 0.365 ± 0.134
1.826AsnAsp: 1.826 ± 0.356
1.607AsnGlu: 1.607 ± 0.437
1.461AsnPhe: 1.461 ± 0.411
1.753AsnGly: 1.753 ± 0.502
0.95AsnHis: 0.95 ± 0.232
1.388AsnIle: 1.388 ± 0.36
1.169AsnLys: 1.169 ± 0.303
2.703AsnLeu: 2.703 ± 0.59
0.731AsnMet: 0.731 ± 0.24
1.753AsnAsn: 1.753 ± 0.462
2.776AsnPro: 2.776 ± 0.524
1.242AsnGln: 1.242 ± 0.377
2.63AsnArg: 2.63 ± 0.551
2.192AsnSer: 2.192 ± 0.452
2.045AsnThr: 2.045 ± 0.474
2.922AsnVal: 2.922 ± 0.478
0.657AsnTrp: 0.657 ± 0.273
1.753AsnTyr: 1.753 ± 0.384
0.0AsnXaa: 0.0 ± 0.0
Pro
7.451ProAla: 7.451 ± 0.676
1.023ProCys: 1.023 ± 0.362
4.164ProAsp: 4.164 ± 0.395
4.602ProGlu: 4.602 ± 0.57
3.287ProPhe: 3.287 ± 0.464
4.31ProGly: 4.31 ± 0.434
2.045ProHis: 2.045 ± 0.39
1.242ProIle: 1.242 ± 0.316
1.607ProLys: 1.607 ± 0.323
6.209ProLeu: 6.209 ± 0.9
1.461ProMet: 1.461 ± 0.291
1.826ProAsn: 1.826 ± 0.495
10.592ProPro: 10.592 ± 1.439
3.36ProGln: 3.36 ± 0.566
5.698ProArg: 5.698 ± 0.663
5.99ProSer: 5.99 ± 0.692
4.748ProThr: 4.748 ± 0.617
4.456ProVal: 4.456 ± 0.564
0.584ProTrp: 0.584 ± 0.203
2.484ProTyr: 2.484 ± 0.396
0.0ProXaa: 0.0 ± 0.0
Gln
2.338GlnAla: 2.338 ± 0.534
0.584GlnCys: 0.584 ± 0.229
1.68GlnAsp: 1.68 ± 0.303
2.63GlnGlu: 2.63 ± 0.396
1.461GlnPhe: 1.461 ± 0.283
2.045GlnGly: 2.045 ± 0.427
1.169GlnHis: 1.169 ± 0.279
0.365GlnIle: 0.365 ± 0.168
0.95GlnLys: 0.95 ± 0.206
5.552GlnLeu: 5.552 ± 0.632
0.804GlnMet: 0.804 ± 0.235
1.388GlnAsn: 1.388 ± 0.436
3.58GlnPro: 3.58 ± 0.546
2.849GlnGln: 2.849 ± 0.617
3.141GlnArg: 3.141 ± 0.517
2.045GlnSer: 2.045 ± 0.345
2.557GlnThr: 2.557 ± 0.368
2.118GlnVal: 2.118 ± 0.253
0.365GlnTrp: 0.365 ± 0.159
1.388GlnTyr: 1.388 ± 0.373
0.0GlnXaa: 0.0 ± 0.0
Arg
6.794ArgAla: 6.794 ± 1.098
1.315ArgCys: 1.315 ± 0.386
4.529ArgAsp: 4.529 ± 0.454
4.31ArgGlu: 4.31 ± 0.619
4.164ArgPhe: 4.164 ± 0.541
5.771ArgGly: 5.771 ± 0.628
2.557ArgHis: 2.557 ± 0.404
1.753ArgIle: 1.753 ± 0.362
1.607ArgLys: 1.607 ± 0.316
9.204ArgLeu: 9.204 ± 1.264
1.096ArgMet: 1.096 ± 0.245
2.776ArgAsn: 2.776 ± 0.614
5.187ArgPro: 5.187 ± 0.848
3.58ArgGln: 3.58 ± 0.49
13.734ArgArg: 13.734 ± 1.914
4.821ArgSer: 4.821 ± 0.547
5.041ArgThr: 5.041 ± 0.864
5.333ArgVal: 5.333 ± 0.752
1.607ArgTrp: 1.607 ± 0.308
2.703ArgTyr: 2.703 ± 0.373
0.0ArgXaa: 0.0 ± 0.0
Ser
4.967SerAla: 4.967 ± 0.609
1.461SerCys: 1.461 ± 0.411
2.703SerAsp: 2.703 ± 0.427
3.214SerGlu: 3.214 ± 0.502
2.338SerPhe: 2.338 ± 0.425
4.602SerGly: 4.602 ± 0.651
1.023SerHis: 1.023 ± 0.301
1.242SerIle: 1.242 ± 0.397
1.242SerLys: 1.242 ± 0.292
7.232SerLeu: 7.232 ± 0.8
1.534SerMet: 1.534 ± 0.342
2.045SerAsn: 2.045 ± 0.451
5.26SerPro: 5.26 ± 0.754
2.338SerGln: 2.338 ± 0.525
6.063SerArg: 6.063 ± 0.684
6.355SerSer: 6.355 ± 1.083
4.164SerThr: 4.164 ± 0.712
4.456SerVal: 4.456 ± 0.534
0.804SerTrp: 0.804 ± 0.285
1.461SerTyr: 1.461 ± 0.287
0.0SerXaa: 0.0 ± 0.0
Thr
5.625ThrAla: 5.625 ± 0.739
0.804ThrCys: 0.804 ± 0.276
2.265ThrAsp: 2.265 ± 0.421
2.411ThrGlu: 2.411 ± 0.453
2.265ThrPhe: 2.265 ± 0.298
4.456ThrGly: 4.456 ± 0.752
1.315ThrHis: 1.315 ± 0.307
1.315ThrIle: 1.315 ± 0.371
1.169ThrLys: 1.169 ± 0.354
6.282ThrLeu: 6.282 ± 0.571
0.584ThrMet: 0.584 ± 0.177
2.118ThrAsn: 2.118 ± 0.635
6.063ThrPro: 6.063 ± 0.753
2.045ThrGln: 2.045 ± 0.339
4.456ThrArg: 4.456 ± 0.589
4.164ThrSer: 4.164 ± 0.694
8.036ThrThr: 8.036 ± 2.877
5.333ThrVal: 5.333 ± 1.098
0.511ThrTrp: 0.511 ± 0.167
2.045ThrTyr: 2.045 ± 0.439
0.0ThrXaa: 0.0 ± 0.0
Val
6.94ValAla: 6.94 ± 0.749
2.045ValCys: 2.045 ± 0.579
3.726ValAsp: 3.726 ± 0.402
4.018ValGlu: 4.018 ± 0.483
2.776ValPhe: 2.776 ± 0.406
3.945ValGly: 3.945 ± 0.568
1.096ValHis: 1.096 ± 0.283
2.265ValIle: 2.265 ± 0.443
1.826ValLys: 1.826 ± 0.406
6.355ValLeu: 6.355 ± 0.73
1.023ValMet: 1.023 ± 0.307
2.484ValAsn: 2.484 ± 0.658
4.018ValPro: 4.018 ± 0.64
2.557ValGln: 2.557 ± 0.578
5.99ValArg: 5.99 ± 0.913
3.726ValSer: 3.726 ± 0.466
4.602ValThr: 4.602 ± 0.62
6.063ValVal: 6.063 ± 0.745
0.804ValTrp: 0.804 ± 0.235
2.63ValTyr: 2.63 ± 0.566
0.0ValXaa: 0.0 ± 0.0
Trp
0.95TrpAla: 0.95 ± 0.289
0.511TrpCys: 0.511 ± 0.209
0.731TrpAsp: 0.731 ± 0.25
1.023TrpGlu: 1.023 ± 0.289
0.438TrpPhe: 0.438 ± 0.166
0.731TrpGly: 0.731 ± 0.28
0.292TrpHis: 0.292 ± 0.144
0.584TrpIle: 0.584 ± 0.338
0.292TrpLys: 0.292 ± 0.133
0.95TrpLeu: 0.95 ± 0.217
0.365TrpMet: 0.365 ± 0.164
0.95TrpAsn: 0.95 ± 0.35
0.731TrpPro: 0.731 ± 0.255
0.584TrpGln: 0.584 ± 0.195
0.95TrpArg: 0.95 ± 0.163
1.315TrpSer: 1.315 ± 0.23
1.023TrpThr: 1.023 ± 0.205
0.804TrpVal: 0.804 ± 0.272
0.292TrpTrp: 0.292 ± 0.152
1.096TrpTyr: 1.096 ± 0.284
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.995TyrAla: 2.995 ± 0.501
0.731TyrCys: 0.731 ± 0.21
3.506TyrAsp: 3.506 ± 0.711
1.826TyrGlu: 1.826 ± 0.335
2.118TyrPhe: 2.118 ± 0.52
1.753TyrGly: 1.753 ± 0.33
1.096TyrHis: 1.096 ± 0.286
0.584TyrIle: 0.584 ± 0.198
1.096TyrLys: 1.096 ± 0.369
4.091TyrLeu: 4.091 ± 0.579
0.95TyrMet: 0.95 ± 0.316
1.315TyrAsn: 1.315 ± 0.319
1.899TyrPro: 1.899 ± 0.301
0.804TyrGln: 0.804 ± 0.237
2.995TyrArg: 2.995 ± 0.425
1.972TyrSer: 1.972 ± 0.349
1.534TyrThr: 1.534 ± 0.285
3.141TyrVal: 3.141 ± 0.509
1.169TyrTrp: 1.169 ± 0.313
1.169TyrTyr: 1.169 ± 0.277
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 37 proteins (13690 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski