Amino acid dipepetide frequency for Beihai tombus-like virus 12

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.652AlaAla: 12.652 ± 3.041
0.506AlaCys: 0.506 ± 0.425
3.543AlaAsp: 3.543 ± 1.092
8.603AlaGlu: 8.603 ± 2.188
1.518AlaPhe: 1.518 ± 0.866
10.121AlaGly: 10.121 ± 1.511
2.024AlaHis: 2.024 ± 1.002
1.012AlaIle: 1.012 ± 0.92
6.073AlaLys: 6.073 ± 2.903
6.579AlaLeu: 6.579 ± 1.491
3.543AlaMet: 3.543 ± 0.63
4.049AlaAsn: 4.049 ± 1.011
3.036AlaPro: 3.036 ± 1.622
5.061AlaGln: 5.061 ± 1.339
9.109AlaArg: 9.109 ± 3.43
8.603AlaSer: 8.603 ± 1.398
8.097AlaThr: 8.097 ± 2.137
8.097AlaVal: 8.097 ± 3.076
0.0AlaTrp: 0.0 ± 0.0
3.036AlaTyr: 3.036 ± 1.212
0.0AlaXaa: 0.0 ± 0.0
Cys
0.506CysAla: 0.506 ± 0.5
1.518CysCys: 1.518 ± 0.811
0.0CysAsp: 0.0 ± 0.0
1.012CysGlu: 1.012 ± 0.92
0.506CysPhe: 0.506 ± 0.372
1.518CysGly: 1.518 ± 0.528
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
2.024CysLeu: 2.024 ± 1.496
1.012CysMet: 1.012 ± 0.92
1.012CysAsn: 1.012 ± 0.851
1.012CysPro: 1.012 ± 0.851
2.024CysGln: 2.024 ± 0.912
3.036CysArg: 3.036 ± 1.333
3.036CysSer: 3.036 ± 0.745
1.012CysThr: 1.012 ± 0.559
1.518CysVal: 1.518 ± 0.752
1.012CysTrp: 1.012 ± 0.38
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.061AspAla: 5.061 ± 0.532
0.0AspCys: 0.0 ± 0.0
3.036AspAsp: 3.036 ± 0.639
0.506AspGlu: 0.506 ± 0.372
1.012AspPhe: 1.012 ± 0.659
4.555AspGly: 4.555 ± 0.414
2.024AspHis: 2.024 ± 0.42
1.518AspIle: 1.518 ± 0.866
1.012AspLys: 1.012 ± 0.851
1.012AspLeu: 1.012 ± 0.456
0.0AspMet: 0.0 ± 0.0
0.506AspAsn: 0.506 ± 0.46
5.061AspPro: 5.061 ± 2.591
0.506AspGln: 0.506 ± 0.425
2.53AspArg: 2.53 ± 0.62
3.036AspSer: 3.036 ± 1.455
3.036AspThr: 3.036 ± 0.82
3.543AspVal: 3.543 ± 2.015
1.012AspTrp: 1.012 ± 0.38
2.53AspTyr: 2.53 ± 1.388
0.0AspXaa: 0.0 ± 0.0
Glu
7.085GluAla: 7.085 ± 2.128
0.506GluCys: 0.506 ± 0.46
0.506GluAsp: 0.506 ± 0.46
3.036GluGlu: 3.036 ± 1.305
3.036GluPhe: 3.036 ± 1.014
3.036GluGly: 3.036 ± 1.14
1.012GluHis: 1.012 ± 0.456
1.518GluIle: 1.518 ± 0.528
1.012GluLys: 1.012 ± 0.482
3.543GluLeu: 3.543 ± 0.715
0.506GluMet: 0.506 ± 0.425
0.0GluAsn: 0.0 ± 0.0
2.024GluPro: 2.024 ± 0.487
2.024GluGln: 2.024 ± 0.842
1.518GluArg: 1.518 ± 0.752
1.012GluSer: 1.012 ± 0.744
4.555GluThr: 4.555 ± 2.221
5.567GluVal: 5.567 ± 2.382
2.024GluTrp: 2.024 ± 0.369
1.012GluTyr: 1.012 ± 0.92
0.0GluXaa: 0.0 ± 0.0
Phe
4.049PheAla: 4.049 ± 1.891
1.012PheCys: 1.012 ± 0.456
2.024PheAsp: 2.024 ± 0.622
3.036PheGlu: 3.036 ± 1.732
0.506PhePhe: 0.506 ± 0.372
3.543PheGly: 3.543 ± 1.443
1.012PheHis: 1.012 ± 0.92
0.506PheIle: 0.506 ± 0.46
0.0PheLys: 0.0 ± 0.0
1.518PheLeu: 1.518 ± 0.807
1.518PheMet: 1.518 ± 0.727
1.012PheAsn: 1.012 ± 0.38
0.0PhePro: 0.0 ± 0.0
1.518PheGln: 1.518 ± 0.713
1.518PheArg: 1.518 ± 0.713
1.012PheSer: 1.012 ± 0.456
0.506PheThr: 0.506 ± 0.372
1.518PheVal: 1.518 ± 0.232
1.012PheTrp: 1.012 ± 0.744
1.518PheTyr: 1.518 ± 0.713
0.0PheXaa: 0.0 ± 0.0
Gly
7.085GlyAla: 7.085 ± 1.587
2.024GlyCys: 2.024 ± 0.487
1.518GlyAsp: 1.518 ± 0.866
1.518GlyGlu: 1.518 ± 1.118
2.53GlyPhe: 2.53 ± 0.625
9.109GlyGly: 9.109 ± 1.955
0.506GlyHis: 0.506 ± 0.627
1.012GlyIle: 1.012 ± 0.559
2.024GlyLys: 2.024 ± 0.87
6.579GlyLeu: 6.579 ± 0.988
1.518GlyMet: 1.518 ± 0.713
2.024GlyAsn: 2.024 ± 0.707
6.073GlyPro: 6.073 ± 2.203
4.555GlyGln: 4.555 ± 1.095
9.109GlyArg: 9.109 ± 2.684
5.061GlySer: 5.061 ± 1.566
2.53GlyThr: 2.53 ± 0.979
8.097GlyVal: 8.097 ± 1.11
0.0GlyTrp: 0.0 ± 0.0
4.049GlyTyr: 4.049 ± 2.1
0.0GlyXaa: 0.0 ± 0.0
His
1.012HisAla: 1.012 ± 0.765
1.518HisCys: 1.518 ± 0.727
1.012HisAsp: 1.012 ± 0.765
0.506HisGlu: 0.506 ± 0.627
0.506HisPhe: 0.506 ± 0.372
0.506HisGly: 0.506 ± 0.425
0.0HisHis: 0.0 ± 0.0
0.506HisIle: 0.506 ± 0.372
1.012HisLys: 1.012 ± 0.482
1.518HisLeu: 1.518 ± 1.38
0.0HisMet: 0.0 ± 0.0
0.506HisAsn: 0.506 ± 0.372
4.049HisPro: 4.049 ± 1.543
0.506HisGln: 0.506 ± 0.627
1.518HisArg: 1.518 ± 0.727
3.543HisSer: 3.543 ± 1.981
0.506HisThr: 0.506 ± 0.372
0.0HisVal: 0.0 ± 0.0
1.012HisTrp: 1.012 ± 0.744
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.518IleAla: 1.518 ± 1.095
1.012IleCys: 1.012 ± 0.682
1.012IleAsp: 1.012 ± 0.456
1.012IleGlu: 1.012 ± 0.482
0.506IlePhe: 0.506 ± 0.372
0.506IleGly: 0.506 ± 0.627
1.012IleHis: 1.012 ± 0.765
0.506IleIle: 0.506 ± 0.627
1.012IleLys: 1.012 ± 0.456
1.518IleLeu: 1.518 ± 0.866
0.506IleMet: 0.506 ± 0.627
1.518IleAsn: 1.518 ± 0.727
2.53IlePro: 2.53 ± 1.469
1.012IleGln: 1.012 ± 0.456
0.0IleArg: 0.0 ± 0.0
1.012IleSer: 1.012 ± 0.92
5.061IleThr: 5.061 ± 1.658
1.518IleVal: 1.518 ± 0.606
0.506IleTrp: 0.506 ± 0.46
1.518IleTyr: 1.518 ± 0.606
0.0IleXaa: 0.0 ± 0.0
Lys
3.036LysAla: 3.036 ± 0.745
2.53LysCys: 2.53 ± 0.62
1.012LysAsp: 1.012 ± 0.744
2.024LysGlu: 2.024 ± 1.115
0.506LysPhe: 0.506 ± 0.46
2.024LysGly: 2.024 ± 0.871
0.0LysHis: 0.0 ± 0.0
1.518LysIle: 1.518 ± 0.727
1.518LysLys: 1.518 ± 1.276
3.543LysLeu: 3.543 ± 1.292
0.506LysMet: 0.506 ± 0.46
0.0LysAsn: 0.0 ± 0.0
4.555LysPro: 4.555 ± 1.363
1.518LysGln: 1.518 ± 0.727
5.061LysArg: 5.061 ± 2.409
1.012LysSer: 1.012 ± 0.456
1.012LysThr: 1.012 ± 0.456
4.049LysVal: 4.049 ± 2.447
0.506LysTrp: 0.506 ± 0.425
2.024LysTyr: 2.024 ± 1.002
0.0LysXaa: 0.0 ± 0.0
Leu
5.061LeuAla: 5.061 ± 2.138
0.506LeuCys: 0.506 ± 0.5
4.555LeuAsp: 4.555 ± 1.171
2.53LeuGlu: 2.53 ± 1.324
2.53LeuPhe: 2.53 ± 0.999
5.061LeuGly: 5.061 ± 1.98
2.024LeuHis: 2.024 ± 1.05
1.518LeuIle: 1.518 ± 0.712
3.036LeuLys: 3.036 ± 1.3
7.591LeuLeu: 7.591 ± 1.895
1.518LeuMet: 1.518 ± 0.712
2.024LeuAsn: 2.024 ± 1.134
13.664LeuPro: 13.664 ± 5.847
1.518LeuGln: 1.518 ± 1.095
6.073LeuArg: 6.073 ± 2.221
4.555LeuSer: 4.555 ± 1.891
3.543LeuThr: 3.543 ± 0.876
3.543LeuVal: 3.543 ± 2.022
1.518LeuTrp: 1.518 ± 0.807
2.024LeuTyr: 2.024 ± 0.42
0.0LeuXaa: 0.0 ± 0.0
Met
4.555MetAla: 4.555 ± 1.11
1.012MetCys: 1.012 ± 0.456
1.012MetAsp: 1.012 ± 0.482
0.506MetGlu: 0.506 ± 0.425
2.024MetPhe: 2.024 ± 1.496
1.518MetGly: 1.518 ± 0.908
0.506MetHis: 0.506 ± 0.46
1.012MetIle: 1.012 ± 1.255
0.506MetLys: 0.506 ± 0.372
1.012MetLeu: 1.012 ± 0.92
1.012MetMet: 1.012 ± 0.92
1.518MetAsn: 1.518 ± 0.716
1.012MetPro: 1.012 ± 0.851
0.0MetGln: 0.0 ± 0.0
1.012MetArg: 1.012 ± 0.92
0.506MetSer: 0.506 ± 0.5
1.012MetThr: 1.012 ± 0.38
0.506MetVal: 0.506 ± 0.46
0.0MetTrp: 0.0 ± 0.0
0.506MetTyr: 0.506 ± 0.372
0.0MetXaa: 0.0 ± 0.0
Asn
4.555AsnAla: 4.555 ± 0.84
0.506AsnCys: 0.506 ± 0.46
1.012AsnAsp: 1.012 ± 0.38
2.024AsnGlu: 2.024 ± 1.05
0.506AsnPhe: 0.506 ± 0.46
2.024AsnGly: 2.024 ± 1.332
0.506AsnHis: 0.506 ± 0.372
1.012AsnIle: 1.012 ± 0.744
0.506AsnLys: 0.506 ± 0.425
1.518AsnLeu: 1.518 ± 1.115
1.012AsnMet: 1.012 ± 0.482
0.506AsnAsn: 0.506 ± 0.46
0.506AsnPro: 0.506 ± 0.425
0.506AsnGln: 0.506 ± 0.372
2.024AsnArg: 2.024 ± 0.889
3.036AsnSer: 3.036 ± 1.622
1.518AsnThr: 1.518 ± 0.727
3.036AsnVal: 3.036 ± 1.755
0.0AsnTrp: 0.0 ± 0.0
0.506AsnTyr: 0.506 ± 0.46
0.0AsnXaa: 0.0 ± 0.0
Pro
6.073ProAla: 6.073 ± 2.09
1.518ProCys: 1.518 ± 0.811
2.53ProAsp: 2.53 ± 0.62
3.036ProGlu: 3.036 ± 1.524
1.518ProPhe: 1.518 ± 1.115
4.555ProGly: 4.555 ± 1.532
1.518ProHis: 1.518 ± 0.752
2.53ProIle: 2.53 ± 0.753
3.036ProLys: 3.036 ± 2.552
11.64ProLeu: 11.64 ± 4.234
2.53ProMet: 2.53 ± 1.199
0.506ProAsn: 0.506 ± 0.372
7.591ProPro: 7.591 ± 1.97
2.53ProGln: 2.53 ± 1.538
5.567ProArg: 5.567 ± 1.549
4.555ProSer: 4.555 ± 0.454
6.073ProThr: 6.073 ± 2.269
13.664ProVal: 13.664 ± 5.278
1.012ProTrp: 1.012 ± 0.682
1.518ProTyr: 1.518 ± 0.866
0.0ProXaa: 0.0 ± 0.0
Gln
3.543GlnAla: 3.543 ± 0.633
0.0GlnCys: 0.0 ± 0.0
1.012GlnAsp: 1.012 ± 0.659
1.518GlnGlu: 1.518 ± 0.716
0.0GlnPhe: 0.0 ± 0.0
3.036GlnGly: 3.036 ± 0.935
0.506GlnHis: 0.506 ± 0.46
1.012GlnIle: 1.012 ± 0.38
2.024GlnLys: 2.024 ± 1.115
2.53GlnLeu: 2.53 ± 0.625
0.506GlnMet: 0.506 ± 0.425
0.0GlnAsn: 0.0 ± 0.0
2.53GlnPro: 2.53 ± 0.959
1.012GlnGln: 1.012 ± 0.456
7.591GlnArg: 7.591 ± 2.039
0.506GlnSer: 0.506 ± 0.425
3.036GlnThr: 3.036 ± 2.132
1.518GlnVal: 1.518 ± 0.606
1.012GlnTrp: 1.012 ± 0.482
1.518GlnTyr: 1.518 ± 0.605
0.0GlnXaa: 0.0 ± 0.0
Arg
9.615ArgAla: 9.615 ± 2.817
2.53ArgCys: 2.53 ± 0.585
4.555ArgAsp: 4.555 ± 0.765
2.53ArgGlu: 2.53 ± 1.538
4.555ArgPhe: 4.555 ± 3.137
6.073ArgGly: 6.073 ± 1.019
2.53ArgHis: 2.53 ± 1.233
1.518ArgIle: 1.518 ± 0.712
5.061ArgLys: 5.061 ± 1.951
4.555ArgLeu: 4.555 ± 1.7
1.012ArgMet: 1.012 ± 0.798
1.518ArgAsn: 1.518 ± 0.727
6.579ArgPro: 6.579 ± 3.889
4.049ArgGln: 4.049 ± 0.576
12.652ArgArg: 12.652 ± 4.912
9.109ArgSer: 9.109 ± 3.319
4.555ArgThr: 4.555 ± 1.051
6.579ArgVal: 6.579 ± 1.042
2.024ArgTrp: 2.024 ± 0.506
0.506ArgTyr: 0.506 ± 0.5
0.0ArgXaa: 0.0 ± 0.0
Ser
10.121SerAla: 10.121 ± 1.361
2.024SerCys: 2.024 ± 1.117
2.53SerAsp: 2.53 ± 0.625
2.024SerGlu: 2.024 ± 0.949
1.012SerPhe: 1.012 ± 0.482
6.579SerGly: 6.579 ± 1.92
0.0SerHis: 0.0 ± 0.0
1.518SerIle: 1.518 ± 0.727
2.53SerLys: 2.53 ± 0.964
4.555SerLeu: 4.555 ± 1.776
0.506SerMet: 0.506 ± 0.425
1.518SerAsn: 1.518 ± 0.716
4.555SerPro: 4.555 ± 1.828
0.0SerGln: 0.0 ± 0.0
7.591SerArg: 7.591 ± 2.923
4.555SerSer: 4.555 ± 1.182
6.073SerThr: 6.073 ± 3.415
6.579SerVal: 6.579 ± 0.965
1.518SerTrp: 1.518 ± 0.606
1.012SerTyr: 1.012 ± 0.482
0.0SerXaa: 0.0 ± 0.0
Thr
4.555ThrAla: 4.555 ± 1.302
0.506ThrCys: 0.506 ± 0.46
1.518ThrAsp: 1.518 ± 0.716
2.024ThrGlu: 2.024 ± 0.964
2.024ThrPhe: 2.024 ± 1.115
5.567ThrGly: 5.567 ± 1.548
1.518ThrHis: 1.518 ± 1.115
0.506ThrIle: 0.506 ± 0.425
2.53ThrLys: 2.53 ± 0.864
3.036ThrLeu: 3.036 ± 0.52
0.506ThrMet: 0.506 ± 0.425
4.555ThrAsn: 4.555 ± 2.762
6.579ThrPro: 6.579 ± 1.477
3.036ThrGln: 3.036 ± 1.946
6.073ThrArg: 6.073 ± 1.947
6.073ThrSer: 6.073 ± 1.984
5.061ThrThr: 5.061 ± 3.056
8.097ThrVal: 8.097 ± 1.508
1.012ThrTrp: 1.012 ± 0.682
1.518ThrTyr: 1.518 ± 0.727
0.0ThrXaa: 0.0 ± 0.0
Val
9.615ValAla: 9.615 ± 2.84
1.012ValCys: 1.012 ± 0.851
7.591ValAsp: 7.591 ± 3.939
5.061ValGlu: 5.061 ± 1.21
2.024ValPhe: 2.024 ± 0.42
4.555ValGly: 4.555 ± 1.238
1.518ValHis: 1.518 ± 0.62
3.543ValIle: 3.543 ± 0.794
3.036ValLys: 3.036 ± 0.463
4.555ValLeu: 4.555 ± 1.0
1.518ValMet: 1.518 ± 0.305
3.036ValAsn: 3.036 ± 1.732
8.603ValPro: 8.603 ± 2.546
2.024ValGln: 2.024 ± 1.115
8.603ValArg: 8.603 ± 1.357
5.567ValSer: 5.567 ± 1.732
4.049ValThr: 4.049 ± 2.482
7.085ValVal: 7.085 ± 2.667
1.518ValTrp: 1.518 ± 0.528
2.53ValTyr: 2.53 ± 0.427
0.0ValXaa: 0.0 ± 0.0
Trp
2.53TrpAla: 2.53 ± 0.595
0.506TrpCys: 0.506 ± 0.627
0.0TrpAsp: 0.0 ± 0.0
0.506TrpGlu: 0.506 ± 0.425
0.506TrpPhe: 0.506 ± 0.372
1.012TrpGly: 1.012 ± 0.744
0.506TrpHis: 0.506 ± 0.372
0.506TrpIle: 0.506 ± 0.46
0.506TrpLys: 0.506 ± 0.372
3.036TrpLeu: 3.036 ± 1.382
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
2.024TrpPro: 2.024 ± 0.818
0.0TrpGln: 0.0 ± 0.0
1.012TrpArg: 1.012 ± 0.744
0.506TrpSer: 0.506 ± 0.372
2.024TrpThr: 2.024 ± 0.76
0.506TrpVal: 0.506 ± 0.5
0.0TrpTrp: 0.0 ± 0.0
1.012TrpTyr: 1.012 ± 0.38
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.036TyrAla: 3.036 ± 1.094
1.012TyrCys: 1.012 ± 0.92
1.518TyrAsp: 1.518 ± 1.115
1.518TyrGlu: 1.518 ± 0.713
1.012TyrPhe: 1.012 ± 0.765
2.024TyrGly: 2.024 ± 1.125
1.012TyrHis: 1.012 ± 0.659
2.024TyrIle: 2.024 ± 0.42
1.518TyrLys: 1.518 ± 0.866
2.53TyrLeu: 2.53 ± 1.769
1.012TyrMet: 1.012 ± 0.482
1.012TyrAsn: 1.012 ± 0.92
1.518TyrPro: 1.518 ± 0.807
1.012TyrGln: 1.012 ± 0.38
1.012TyrArg: 1.012 ± 0.92
0.506TyrSer: 0.506 ± 0.46
3.036TyrThr: 3.036 ± 0.639
2.024TyrVal: 2.024 ± 0.622
0.0TyrTrp: 0.0 ± 0.0
2.024TyrTyr: 2.024 ± 1.84
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1977 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski