Amino acid dipepetide frequency for Deinococcus deserti (strain DSM 17065 / CIP 109153 / LMG 22923 / VCD115)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.207AlaAla: 15.207 ± 0.156	0.871AlaCys: 0.871 ± 0.03	5.492AlaAsp: 5.492 ± 0.079	6.336AlaGlu: 6.336 ± 0.1	4.002AlaPhe: 4.002 ± 0.067	10.868AlaGly: 10.868 ± 0.113	2.726AlaHis: 2.726 ± 0.057	3.641AlaIle: 3.641 ± 0.062	2.231AlaLys: 2.231 ± 0.063	15.528AlaLeu: 15.528 ± 0.178	2.447AlaMet: 2.447 ± 0.051	2.189AlaAsn: 2.189 ± 0.052	6.059AlaPro: 6.059 ± 0.113	6.096AlaGln: 6.096 ± 0.08	9.76AlaArg: 9.76 ± 0.116	6.081AlaSer: 6.081 ± 0.085	5.885AlaThr: 5.885 ± 0.081	8.757AlaVal: 8.757 ± 0.108	1.681AlaTrp: 1.681 ± 0.046	2.843AlaTyr: 2.843 ± 0.055	0.0AlaXaa: 0.0 ± 0.0
Cys	0.751CysAla: 0.751 ± 0.031	0.071CysCys: 0.071 ± 0.009	0.313CysAsp: 0.313 ± 0.018	0.285CysGlu: 0.285 ± 0.017	0.165CysPhe: 0.165 ± 0.014	0.701CysGly: 0.701 ± 0.03	0.15CysHis: 0.15 ± 0.012	0.223CysIle: 0.223 ± 0.015	0.117CysLys: 0.117 ± 0.01	0.598CysLeu: 0.598 ± 0.031	0.133CysMet: 0.133 ± 0.012	0.162CysAsn: 0.162 ± 0.013	0.396CysPro: 0.396 ± 0.022	0.209CysGln: 0.209 ± 0.014	0.431CysArg: 0.431 ± 0.021	0.373CysSer: 0.373 ± 0.019	0.412CysThr: 0.412 ± 0.021	0.469CysVal: 0.469 ± 0.022	0.079CysTrp: 0.079 ± 0.009	0.123CysTyr: 0.123 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	6.147AspAla: 6.147 ± 0.09	0.249AspCys: 0.249 ± 0.015	2.325AspAsp: 2.325 ± 0.047	3.009AspGlu: 3.009 ± 0.054	1.718AspPhe: 1.718 ± 0.038	4.213AspGly: 4.213 ± 0.063	1.283AspHis: 1.283 ± 0.036	1.995AspIle: 1.995 ± 0.046	1.047AspLys: 1.047 ± 0.034	6.643AspLeu: 6.643 ± 0.096	0.973AspMet: 0.973 ± 0.031	1.017AspAsn: 1.017 ± 0.032	3.455AspPro: 3.455 ± 0.053	1.76AspGln: 1.76 ± 0.041	3.495AspArg: 3.495 ± 0.058	2.241AspSer: 2.241 ± 0.047	2.792AspThr: 2.792 ± 0.056	4.342AspVal: 4.342 ± 0.067	0.812AspTrp: 0.812 ± 0.03	1.11AspTyr: 1.11 ± 0.036	0.0AspXaa: 0.0 ± 0.0
Glu	7.481GluAla: 7.481 ± 0.105	0.258GluCys: 0.258 ± 0.017	2.703GluAsp: 2.703 ± 0.054	3.099GluGlu: 3.099 ± 0.071	1.734GluPhe: 1.734 ± 0.041	4.419GluGly: 4.419 ± 0.066	1.492GluHis: 1.492 ± 0.041	2.2GluIle: 2.2 ± 0.052	1.584GluLys: 1.584 ± 0.045	6.461GluLeu: 6.461 ± 0.088	1.068GluMet: 1.068 ± 0.031	1.306GluAsn: 1.306 ± 0.036	2.386GluPro: 2.386 ± 0.061	2.674GluGln: 2.674 ± 0.054	4.872GluArg: 4.872 ± 0.075	2.286GluSer: 2.286 ± 0.046	3.027GluThr: 3.027 ± 0.054	4.852GluVal: 4.852 ± 0.07	0.767GluTrp: 0.767 ± 0.027	1.289GluTyr: 1.289 ± 0.031	0.0GluXaa: 0.0 ± 0.0
Phe	3.44PheAla: 3.44 ± 0.061	0.212PheCys: 0.212 ± 0.015	1.874PheAsp: 1.874 ± 0.043	1.881PheGlu: 1.881 ± 0.047	0.99PhePhe: 0.99 ± 0.034	2.992PheGly: 2.992 ± 0.05	0.647PheHis: 0.647 ± 0.025	1.19PheIle: 1.19 ± 0.039	0.857PheLys: 0.857 ± 0.031	3.248PheLeu: 3.248 ± 0.058	0.689PheMet: 0.689 ± 0.024	0.917PheAsn: 0.917 ± 0.028	1.713PhePro: 1.713 ± 0.038	1.131PheGln: 1.131 ± 0.04	1.976PheArg: 1.976 ± 0.044	1.939PheSer: 1.939 ± 0.044	2.216PheThr: 2.216 ± 0.048	2.412PheVal: 2.412 ± 0.047	0.429PheTrp: 0.429 ± 0.024	0.798PheTyr: 0.798 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	9.276GlyAla: 9.276 ± 0.106	0.593GlyCys: 0.593 ± 0.026	3.972GlyAsp: 3.972 ± 0.061	4.991GlyGlu: 4.991 ± 0.072	3.051GlyPhe: 3.051 ± 0.06	7.7GlyGly: 7.7 ± 0.117	2.118GlyHis: 2.118 ± 0.049	3.539GlyIle: 3.539 ± 0.063	2.727GlyLys: 2.727 ± 0.057	9.979GlyLeu: 9.979 ± 0.117	2.09GlyMet: 2.09 ± 0.048	2.264GlyAsn: 2.264 ± 0.058	3.635GlyPro: 3.635 ± 0.063	3.996GlyGln: 3.996 ± 0.068	6.188GlyArg: 6.188 ± 0.084	4.658GlySer: 4.658 ± 0.08	5.698GlyThr: 5.698 ± 0.087	7.587GlyVal: 7.587 ± 0.088	1.344GlyTrp: 1.344 ± 0.036	2.286GlyTyr: 2.286 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	2.916HisAla: 2.916 ± 0.054	0.142HisCys: 0.142 ± 0.012	1.271HisAsp: 1.271 ± 0.034	1.324HisGlu: 1.324 ± 0.042	0.734HisPhe: 0.734 ± 0.027	2.097HisGly: 2.097 ± 0.048	0.719HisHis: 0.719 ± 0.029	0.787HisIle: 0.787 ± 0.027	0.417HisLys: 0.417 ± 0.021	2.878HisLeu: 2.878 ± 0.065	0.407HisMet: 0.407 ± 0.019	0.478HisAsn: 0.478 ± 0.024	1.737HisPro: 1.737 ± 0.046	0.823HisGln: 0.823 ± 0.025	1.459HisArg: 1.459 ± 0.038	1.145HisSer: 1.145 ± 0.032	1.37HisThr: 1.37 ± 0.037	1.691HisVal: 1.691 ± 0.04	0.34HisTrp: 0.34 ± 0.018	0.575HisTyr: 0.575 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	4.021IleAla: 4.021 ± 0.072	0.239IleCys: 0.239 ± 0.015	1.966IleAsp: 1.966 ± 0.051	2.32IleGlu: 2.32 ± 0.046	1.091IlePhe: 1.091 ± 0.035	3.415IleGly: 3.415 ± 0.063	0.878IleHis: 0.878 ± 0.027	1.432IleIle: 1.432 ± 0.041	0.982IleLys: 0.982 ± 0.032	3.618IleLeu: 3.618 ± 0.062	0.705IleMet: 0.705 ± 0.028	1.123IleAsn: 1.123 ± 0.035	2.17IlePro: 2.17 ± 0.046	1.327IleGln: 1.327 ± 0.037	2.672IleArg: 2.672 ± 0.054	2.244IleSer: 2.244 ± 0.048	2.477IleThr: 2.477 ± 0.058	2.939IleVal: 2.939 ± 0.06	0.413IleTrp: 0.413 ± 0.022	0.837IleTyr: 0.837 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	3.064LysAla: 3.064 ± 0.073	0.113LysCys: 0.113 ± 0.011	1.27LysAsp: 1.27 ± 0.04	1.21LysGlu: 1.21 ± 0.037	0.718LysPhe: 0.718 ± 0.028	2.068LysGly: 2.068 ± 0.054	0.533LysHis: 0.533 ± 0.022	1.008LysIle: 1.008 ± 0.039	0.964LysLys: 0.964 ± 0.04	2.548LysLeu: 2.548 ± 0.058	0.596LysMet: 0.596 ± 0.024	0.784LysAsn: 0.784 ± 0.026	1.457LysPro: 1.457 ± 0.041	0.857LysGln: 0.857 ± 0.033	1.676LysArg: 1.676 ± 0.052	1.244LysSer: 1.244 ± 0.035	1.603LysThr: 1.603 ± 0.041	2.238LysVal: 2.238 ± 0.061	0.28LysTrp: 0.28 ± 0.016	0.67LysTyr: 0.67 ± 0.027	0.0LysXaa: 0.0 ± 0.0
Leu	13.514LeuAla: 13.514 ± 0.148	0.727LeuCys: 0.727 ± 0.029	6.111LeuAsp: 6.111 ± 0.081	6.435LeuGlu: 6.435 ± 0.081	2.871LeuPhe: 2.871 ± 0.057	10.131LeuGly: 10.131 ± 0.123	2.685LeuHis: 2.685 ± 0.055	4.522LeuIle: 4.522 ± 0.078	3.25LeuLys: 3.25 ± 0.064	12.837LeuLeu: 12.837 ± 0.158	2.417LeuMet: 2.417 ± 0.047	3.519LeuAsn: 3.519 ± 0.061	6.993LeuPro: 6.993 ± 0.096	3.875LeuGln: 3.875 ± 0.067	8.664LeuArg: 8.664 ± 0.123	7.541LeuSer: 7.541 ± 0.097	7.8LeuThr: 7.8 ± 0.092	7.637LeuVal: 7.637 ± 0.095	1.274LeuTrp: 1.274 ± 0.041	2.328LeuTyr: 2.328 ± 0.057	0.0LeuXaa: 0.0 ± 0.0
Met	2.084MetAla: 2.084 ± 0.041	0.097MetCys: 0.097 ± 0.009	0.981MetAsp: 0.981 ± 0.033	0.891MetGlu: 0.891 ± 0.031	0.568MetPhe: 0.568 ± 0.024	1.599MetGly: 1.599 ± 0.039	0.473MetHis: 0.473 ± 0.022	0.882MetIle: 0.882 ± 0.032	0.785MetLys: 0.785 ± 0.029	2.25MetLeu: 2.25 ± 0.045	0.457MetMet: 0.457 ± 0.021	0.852MetAsn: 0.852 ± 0.029	1.19MetPro: 1.19 ± 0.033	0.847MetGln: 0.847 ± 0.028	1.501MetArg: 1.501 ± 0.042	1.326MetSer: 1.326 ± 0.037	2.087MetThr: 2.087 ± 0.036	1.335MetVal: 1.335 ± 0.039	0.193MetTrp: 0.193 ± 0.016	0.416MetTyr: 0.416 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.046AsnAla: 3.046 ± 0.068	0.154AsnCys: 0.154 ± 0.013	1.223AsnAsp: 1.223 ± 0.037	1.121AsnGlu: 1.121 ± 0.036	0.886AsnPhe: 0.886 ± 0.032	2.136AsnGly: 2.136 ± 0.052	0.531AsnHis: 0.531 ± 0.024	1.097AsnIle: 1.097 ± 0.031	0.618AsnLys: 0.618 ± 0.023	3.028AsnLeu: 3.028 ± 0.054	0.549AsnMet: 0.549 ± 0.021	0.721AsnAsn: 0.721 ± 0.033	1.968AsnPro: 1.968 ± 0.046	0.786AsnGln: 0.786 ± 0.031	1.637AsnArg: 1.637 ± 0.042	1.267AsnSer: 1.267 ± 0.036	1.585AsnThr: 1.585 ± 0.047	2.246AsnVal: 2.246 ± 0.055	0.368AsnTrp: 0.368 ± 0.016	0.637AsnTyr: 0.637 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	7.341ProAla: 7.341 ± 0.109	0.282ProCys: 0.282 ± 0.018	3.94ProAsp: 3.94 ± 0.06	4.438ProGlu: 4.438 ± 0.071	1.76ProPhe: 1.76 ± 0.04	5.535ProGly: 5.535 ± 0.089	1.332ProHis: 1.332 ± 0.035	1.527ProIle: 1.527 ± 0.038	1.241ProLys: 1.241 ± 0.037	5.912ProLeu: 5.912 ± 0.088	1.064ProMet: 1.064 ± 0.026	1.289ProAsn: 1.289 ± 0.036	2.688ProPro: 2.688 ± 0.076	2.282ProGln: 2.282 ± 0.048	3.198ProArg: 3.198 ± 0.056	2.706ProSer: 2.706 ± 0.057	2.952ProThr: 2.952 ± 0.059	4.954ProVal: 4.954 ± 0.073	0.728ProTrp: 0.728 ± 0.028	1.294ProTyr: 1.294 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	5.909GlnAla: 5.909 ± 0.092	0.178GlnCys: 0.178 ± 0.013	2.117GlnAsp: 2.117 ± 0.039	2.394GlnGlu: 2.394 ± 0.053	1.018GlnPhe: 1.018 ± 0.033	3.663GlnGly: 3.663 ± 0.054	0.912GlnHis: 0.912 ± 0.029	1.465GlnIle: 1.465 ± 0.034	1.03GlnLys: 1.03 ± 0.038	4.092GlnLeu: 4.092 ± 0.067	0.77GlnMet: 0.77 ± 0.024	1.083GlnAsn: 1.083 ± 0.033	2.361GlnPro: 2.361 ± 0.046	1.825GlnGln: 1.825 ± 0.046	2.83GlnArg: 2.83 ± 0.054	1.931GlnSer: 1.931 ± 0.044	2.347GlnThr: 2.347 ± 0.05	3.496GlnVal: 3.496 ± 0.055	0.461GlnTrp: 0.461 ± 0.022	0.811GlnTyr: 0.811 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	8.657ArgAla: 8.657 ± 0.116	0.393ArgCys: 0.393 ± 0.021	3.903ArgAsp: 3.903 ± 0.07	5.104ArgGlu: 5.104 ± 0.086	2.403ArgPhe: 2.403 ± 0.051	5.415ArgGly: 5.415 ± 0.07	1.774ArgHis: 1.774 ± 0.041	2.809ArgIle: 2.809 ± 0.053	1.736ArgLys: 1.736 ± 0.049	8.11ArgLeu: 8.11 ± 0.103	1.641ArgMet: 1.641 ± 0.037	1.743ArgAsn: 1.743 ± 0.046	3.798ArgPro: 3.798 ± 0.071	3.054ArgGln: 3.054 ± 0.063	5.43ArgArg: 5.43 ± 0.084	3.686ArgSer: 3.686 ± 0.057	4.371ArgThr: 4.371 ± 0.066	6.313ArgVal: 6.313 ± 0.083	1.064ArgTrp: 1.064 ± 0.036	1.864ArgTyr: 1.864 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	6.338SerAla: 6.338 ± 0.073	0.386SerCys: 0.386 ± 0.022	2.548SerAsp: 2.548 ± 0.052	2.666SerGlu: 2.666 ± 0.056	1.923SerPhe: 1.923 ± 0.046	6.03SerGly: 6.03 ± 0.095	1.104SerHis: 1.104 ± 0.031	1.83SerIle: 1.83 ± 0.041	1.235SerLys: 1.235 ± 0.035	5.755SerLeu: 5.755 ± 0.082	1.208SerMet: 1.208 ± 0.033	1.306SerAsn: 1.306 ± 0.04	3.189SerPro: 3.189 ± 0.06	1.798SerGln: 1.798 ± 0.043	3.859SerArg: 3.859 ± 0.076	3.269SerSer: 3.269 ± 0.068	3.13SerThr: 3.13 ± 0.066	4.402SerVal: 4.402 ± 0.064	0.808SerTrp: 0.808 ± 0.033	1.18SerTyr: 1.18 ± 0.029	0.0SerXaa: 0.0 ± 0.0
Thr	6.633ThrAla: 6.633 ± 0.081	0.387ThrCys: 0.387 ± 0.024	2.961ThrAsp: 2.961 ± 0.057	2.852ThrGlu: 2.852 ± 0.054	2.266ThrPhe: 2.266 ± 0.048	5.516ThrGly: 5.516 ± 0.082	1.37ThrHis: 1.37 ± 0.038	2.072ThrIle: 2.072 ± 0.052	1.05ThrLys: 1.05 ± 0.038	8.317ThrLeu: 8.317 ± 0.097	0.997ThrMet: 0.997 ± 0.031	1.394ThrAsn: 1.394 ± 0.045	4.676ThrPro: 4.676 ± 0.069	2.133ThrGln: 2.133 ± 0.047	4.282ThrArg: 4.282 ± 0.062	3.36ThrSer: 3.36 ± 0.066	3.659ThrThr: 3.659 ± 0.094	5.284ThrVal: 5.284 ± 0.097	0.798ThrTrp: 0.798 ± 0.026	1.583ThrTyr: 1.583 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	8.612ValAla: 8.612 ± 0.101	0.524ValCys: 0.524 ± 0.025	3.735ValAsp: 3.735 ± 0.066	3.88ValGlu: 3.88 ± 0.058	2.501ValPhe: 2.501 ± 0.046	5.905ValGly: 5.905 ± 0.081	1.703ValHis: 1.703 ± 0.044	3.52ValIle: 3.52 ± 0.066	2.109ValLys: 2.109 ± 0.054	9.144ValLeu: 9.144 ± 0.121	1.881ValMet: 1.881 ± 0.044	2.397ValAsn: 2.397 ± 0.056	4.55ValPro: 4.55 ± 0.063	3.662ValGln: 3.662 ± 0.056	6.259ValArg: 6.259 ± 0.093	4.652ValSer: 4.652 ± 0.077	5.766ValThr: 5.766 ± 0.087	6.277ValVal: 6.277 ± 0.09	1.051ValTrp: 1.051 ± 0.033	1.803ValTyr: 1.803 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.417TrpAla: 1.417 ± 0.044	0.112TrpCys: 0.112 ± 0.01	0.666TrpAsp: 0.666 ± 0.024	0.596TrpGlu: 0.596 ± 0.024	0.382TrpPhe: 0.382 ± 0.02	1.015TrpGly: 1.015 ± 0.031	0.356TrpHis: 0.356 ± 0.018	0.446TrpIle: 0.446 ± 0.022	0.403TrpLys: 0.403 ± 0.019	1.615TrpLeu: 1.615 ± 0.045	0.333TrpMet: 0.333 ± 0.017	0.492TrpAsn: 0.492 ± 0.022	0.709TrpPro: 0.709 ± 0.025	0.653TrpGln: 0.653 ± 0.024	1.088TrpArg: 1.088 ± 0.034	0.747TrpSer: 0.747 ± 0.032	0.93TrpThr: 0.93 ± 0.037	1.015TrpVal: 1.015 ± 0.033	0.255TrpTrp: 0.255 ± 0.018	0.26TrpTyr: 0.26 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.846TyrAla: 2.846 ± 0.06	0.171TyrCys: 0.171 ± 0.013	1.255TyrAsp: 1.255 ± 0.038	1.126TyrGlu: 1.126 ± 0.035	0.768TyrPhe: 0.768 ± 0.025	2.275TyrGly: 2.275 ± 0.047	0.524TyrHis: 0.524 ± 0.022	0.685TyrIle: 0.685 ± 0.026	0.52TyrLys: 0.52 ± 0.021	2.571TyrLeu: 2.571 ± 0.052	0.388TyrMet: 0.388 ± 0.021	0.569TyrAsn: 0.569 ± 0.025	1.332TyrPro: 1.332 ± 0.034	0.901TyrGln: 0.901 ± 0.028	1.992TyrArg: 1.992 ± 0.048	1.27TyrSer: 1.27 ± 0.043	1.484TyrThr: 1.484 ± 0.041	1.686TyrVal: 1.686 ± 0.043	0.345TyrTrp: 0.345 ± 0.017	0.58TyrTyr: 0.58 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3459 proteins (1081085 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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