Amino acid dipepetide frequency for Zebra finch circovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.364AlaAla: 7.364 ± 1.497
0.0AlaCys: 0.0 ± 0.0
1.473AlaAsp: 1.473 ± 2.068
1.473AlaGlu: 1.473 ± 1.055
4.418AlaPhe: 4.418 ± 3.051
7.364AlaGly: 7.364 ± 1.892
1.473AlaHis: 1.473 ± 0.976
1.473AlaIle: 1.473 ± 0.976
2.946AlaLys: 2.946 ± 1.851
2.946AlaLeu: 2.946 ± 1.952
4.418AlaMet: 4.418 ± 1.304
4.418AlaAsn: 4.418 ± 1.667
2.946AlaPro: 2.946 ± 1.952
0.0AlaGln: 0.0 ± 0.0
11.782AlaArg: 11.782 ± 2.956
1.473AlaSer: 1.473 ± 1.959
1.473AlaThr: 1.473 ± 1.959
5.891AlaVal: 5.891 ± 2.398
4.418AlaTrp: 4.418 ± 3.051
2.946AlaTyr: 2.946 ± 1.851
0.0AlaXaa: 0.0 ± 0.0
Cys
1.473CysAla: 1.473 ± 1.959
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
2.946CysGlu: 2.946 ± 1.807
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.473CysLys: 1.473 ± 0.976
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
2.946CysPro: 2.946 ± 3.919
0.0CysGln: 0.0 ± 0.0
1.473CysArg: 1.473 ± 1.959
1.473CysSer: 1.473 ± 0.976
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.473CysTyr: 1.473 ± 0.976
0.0CysXaa: 0.0 ± 0.0
Asp
4.418AspAla: 4.418 ± 1.517
0.0AspCys: 0.0 ± 0.0
1.473AspAsp: 1.473 ± 0.976
2.946AspGlu: 2.946 ± 0.868
5.891AspPhe: 5.891 ± 1.736
4.418AspGly: 4.418 ± 1.667
4.418AspHis: 4.418 ± 2.812
1.473AspIle: 1.473 ± 0.976
0.0AspLys: 0.0 ± 0.0
2.946AspLeu: 2.946 ± 1.952
0.0AspMet: 0.0 ± 0.0
1.473AspAsn: 1.473 ± 0.976
1.473AspPro: 1.473 ± 1.055
0.0AspGln: 0.0 ± 0.0
1.473AspArg: 1.473 ± 0.976
1.473AspSer: 1.473 ± 1.055
1.473AspThr: 1.473 ± 1.055
2.946AspVal: 2.946 ± 1.952
2.946AspTrp: 2.946 ± 0.868
1.473AspTyr: 1.473 ± 1.055
0.0AspXaa: 0.0 ± 0.0
Glu
4.418GluAla: 4.418 ± 1.582
0.0GluCys: 0.0 ± 0.0
5.891GluAsp: 5.891 ± 1.736
4.418GluGlu: 4.418 ± 2.928
4.418GluPhe: 4.418 ± 1.517
2.946GluGly: 2.946 ± 1.952
0.0GluHis: 0.0 ± 0.0
0.0GluIle: 0.0 ± 0.0
4.418GluLys: 4.418 ± 1.517
2.946GluLeu: 2.946 ± 1.807
0.0GluMet: 0.0 ± 0.0
1.473GluAsn: 1.473 ± 0.976
4.418GluPro: 4.418 ± 2.288
4.418GluGln: 4.418 ± 2.928
2.946GluArg: 2.946 ± 0.868
4.418GluSer: 4.418 ± 1.304
2.946GluThr: 2.946 ± 1.851
4.418GluVal: 4.418 ± 2.928
0.0GluTrp: 0.0 ± 0.0
4.418GluTyr: 4.418 ± 1.304
0.0GluXaa: 0.0 ± 0.0
Phe
1.473PheAla: 1.473 ± 1.959
1.473PheCys: 1.473 ± 0.976
0.0PheAsp: 0.0 ± 0.0
2.946PheGlu: 2.946 ± 0.868
1.473PhePhe: 1.473 ± 1.055
4.418PheGly: 4.418 ± 1.582
0.0PheHis: 0.0 ± 0.0
1.473PheIle: 1.473 ± 1.055
4.418PheLys: 4.418 ± 1.667
1.473PheLeu: 1.473 ± 0.976
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
1.473PhePro: 1.473 ± 1.055
1.473PheGln: 1.473 ± 1.055
5.891PheArg: 5.891 ± 2.651
2.946PheSer: 2.946 ± 0.868
2.946PheThr: 2.946 ± 1.952
1.473PheVal: 1.473 ± 0.976
0.0PheTrp: 0.0 ± 0.0
2.946PheTyr: 2.946 ± 1.952
0.0PheXaa: 0.0 ± 0.0
Gly
5.891GlyAla: 5.891 ± 1.736
1.473GlyCys: 1.473 ± 2.068
4.418GlyAsp: 4.418 ± 1.517
4.418GlyGlu: 4.418 ± 1.582
4.418GlyPhe: 4.418 ± 1.517
4.418GlyGly: 4.418 ± 6.203
4.418GlyHis: 4.418 ± 2.757
1.473GlyIle: 1.473 ± 2.068
2.946GlyLys: 2.946 ± 1.952
2.946GlyLeu: 2.946 ± 0.868
0.0GlyMet: 0.0 ± 0.0
1.473GlyAsn: 1.473 ± 0.976
4.418GlyPro: 4.418 ± 2.812
2.946GlyGln: 2.946 ± 1.807
8.837GlyArg: 8.837 ± 6.084
2.946GlySer: 2.946 ± 1.952
10.309GlyThr: 10.309 ± 3.22
2.946GlyVal: 2.946 ± 0.868
2.946GlyTrp: 2.946 ± 1.807
1.473GlyTyr: 1.473 ± 0.976
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
2.946HisPhe: 2.946 ± 0.868
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
1.473HisLys: 1.473 ± 0.976
5.891HisLeu: 5.891 ± 1.736
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.473HisPro: 1.473 ± 0.976
0.0HisGln: 0.0 ± 0.0
5.891HisArg: 5.891 ± 4.393
1.473HisSer: 1.473 ± 1.959
2.946HisThr: 2.946 ± 1.851
0.0HisVal: 0.0 ± 0.0
4.418HisTrp: 4.418 ± 1.667
2.946HisTyr: 2.946 ± 0.868
0.0HisXaa: 0.0 ± 0.0
Ile
1.473IleAla: 1.473 ± 2.068
0.0IleCys: 0.0 ± 0.0
1.473IleAsp: 1.473 ± 0.976
0.0IleGlu: 0.0 ± 0.0
0.0IlePhe: 0.0 ± 0.0
4.418IleGly: 4.418 ± 2.217
0.0IleHis: 0.0 ± 0.0
2.946IleIle: 2.946 ± 1.952
0.0IleLys: 0.0 ± 0.0
2.946IleLeu: 2.946 ± 0.868
1.473IleMet: 1.473 ± 1.055
2.946IleAsn: 2.946 ± 1.952
2.946IlePro: 2.946 ± 0.868
2.946IleGln: 2.946 ± 2.109
1.473IleArg: 1.473 ± 1.055
0.0IleSer: 0.0 ± 0.0
2.946IleThr: 2.946 ± 0.868
4.418IleVal: 4.418 ± 2.928
0.0IleTrp: 0.0 ± 0.0
2.946IleTyr: 2.946 ± 2.109
0.0IleXaa: 0.0 ± 0.0
Lys
4.418LysAla: 4.418 ± 1.304
1.473LysCys: 1.473 ± 0.976
2.946LysAsp: 2.946 ± 0.868
2.946LysGlu: 2.946 ± 1.952
1.473LysPhe: 1.473 ± 0.976
5.891LysGly: 5.891 ± 2.398
0.0LysHis: 0.0 ± 0.0
1.473LysIle: 1.473 ± 0.976
8.837LysLys: 8.837 ± 4.286
2.946LysLeu: 2.946 ± 0.868
1.473LysMet: 1.473 ± 0.976
0.0LysAsn: 0.0 ± 0.0
1.473LysPro: 1.473 ± 0.976
2.946LysGln: 2.946 ± 1.952
4.418LysArg: 4.418 ± 1.304
2.946LysSer: 2.946 ± 1.851
5.891LysThr: 5.891 ± 1.483
5.891LysVal: 5.891 ± 1.736
4.418LysTrp: 4.418 ± 1.517
1.473LysTyr: 1.473 ± 0.976
0.0LysXaa: 0.0 ± 0.0
Leu
8.837LeuAla: 8.837 ± 2.149
0.0LeuCys: 0.0 ± 0.0
0.0LeuAsp: 0.0 ± 0.0
1.473LeuGlu: 1.473 ± 1.055
2.946LeuPhe: 2.946 ± 0.868
1.473LeuGly: 1.473 ± 1.055
1.473LeuHis: 1.473 ± 0.976
0.0LeuIle: 0.0 ± 0.0
4.418LeuLys: 4.418 ± 1.517
5.891LeuLeu: 5.891 ± 1.445
2.946LeuMet: 2.946 ± 1.952
5.891LeuAsn: 5.891 ± 1.445
10.309LeuPro: 10.309 ± 3.036
2.946LeuGln: 2.946 ± 0.868
8.837LeuArg: 8.837 ± 2.779
1.473LeuSer: 1.473 ± 1.055
8.837LeuThr: 8.837 ± 1.555
1.473LeuVal: 1.473 ± 1.055
1.473LeuTrp: 1.473 ± 2.068
0.0LeuTyr: 0.0 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.473MetAla: 1.473 ± 2.068
0.0MetCys: 0.0 ± 0.0
1.473MetAsp: 1.473 ± 1.055
1.473MetGlu: 1.473 ± 1.055
1.473MetPhe: 1.473 ± 1.055
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.473MetIle: 1.473 ± 0.976
2.946MetLys: 2.946 ± 1.952
1.473MetLeu: 1.473 ± 1.055
0.0MetMet: 0.0 ± 0.0
1.473MetAsn: 1.473 ± 1.959
1.473MetPro: 1.473 ± 0.976
0.0MetGln: 0.0 ± 0.0
1.473MetArg: 1.473 ± 1.959
1.473MetSer: 1.473 ± 1.055
1.473MetThr: 1.473 ± 0.976
0.0MetVal: 0.0 ± 0.0
2.946MetTrp: 2.946 ± 0.868
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.473AsnAla: 1.473 ± 1.959
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
8.837AsnGlu: 8.837 ± 1.357
0.0AsnPhe: 0.0 ± 0.0
0.0AsnGly: 0.0 ± 0.0
1.473AsnHis: 1.473 ± 1.055
0.0AsnIle: 0.0 ± 0.0
1.473AsnLys: 1.473 ± 0.976
4.418AsnLeu: 4.418 ± 2.757
0.0AsnMet: 0.0 ± 0.0
2.946AsnAsn: 2.946 ± 0.868
2.946AsnPro: 2.946 ± 0.868
1.473AsnGln: 1.473 ± 0.976
4.418AsnArg: 4.418 ± 1.667
1.473AsnSer: 1.473 ± 2.068
2.946AsnThr: 2.946 ± 0.868
1.473AsnVal: 1.473 ± 0.976
1.473AsnTrp: 1.473 ± 1.055
1.473AsnTyr: 1.473 ± 0.976
0.0AsnXaa: 0.0 ± 0.0
Pro
4.418ProAla: 4.418 ± 1.304
1.473ProCys: 1.473 ± 0.976
4.418ProAsp: 4.418 ± 2.217
2.946ProGlu: 2.946 ± 1.851
2.946ProPhe: 2.946 ± 0.868
1.473ProGly: 1.473 ± 2.068
2.946ProHis: 2.946 ± 1.952
4.418ProIle: 4.418 ± 1.304
4.418ProLys: 4.418 ± 1.304
7.364ProLeu: 7.364 ± 3.746
1.473ProMet: 1.473 ± 1.777
1.473ProAsn: 1.473 ± 1.055
1.473ProPro: 1.473 ± 0.976
1.473ProGln: 1.473 ± 1.055
7.364ProArg: 7.364 ± 2.44
8.837ProSer: 8.837 ± 7.369
7.364ProThr: 7.364 ± 2.358
1.473ProVal: 1.473 ± 0.976
1.473ProTrp: 1.473 ± 2.068
1.473ProTyr: 1.473 ± 1.055
0.0ProXaa: 0.0 ± 0.0
Gln
4.418GlnAla: 4.418 ± 1.517
0.0GlnCys: 0.0 ± 0.0
1.473GlnAsp: 1.473 ± 1.055
1.473GlnGlu: 1.473 ± 0.976
0.0GlnPhe: 0.0 ± 0.0
5.891GlnGly: 5.891 ± 1.445
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
1.473GlnLys: 1.473 ± 0.976
4.418GlnLeu: 4.418 ± 1.582
4.418GlnMet: 4.418 ± 1.667
0.0GlnAsn: 0.0 ± 0.0
0.0GlnPro: 0.0 ± 0.0
0.0GlnGln: 0.0 ± 0.0
0.0GlnArg: 0.0 ± 0.0
0.0GlnSer: 0.0 ± 0.0
2.946GlnThr: 2.946 ± 2.109
1.473GlnVal: 1.473 ± 1.055
1.473GlnTrp: 1.473 ± 1.055
2.946GlnTyr: 2.946 ± 0.868
0.0GlnXaa: 0.0 ± 0.0
Arg
8.837ArgAla: 8.837 ± 1.99
0.0ArgCys: 0.0 ± 0.0
1.473ArgAsp: 1.473 ± 0.976
2.946ArgGlu: 2.946 ± 1.952
0.0ArgPhe: 0.0 ± 0.0
11.782ArgGly: 11.782 ± 5.559
4.418ArgHis: 4.418 ± 3.164
4.418ArgIle: 4.418 ± 1.667
2.946ArgLys: 2.946 ± 2.109
10.309ArgLeu: 10.309 ± 4.302
0.0ArgMet: 0.0 ± 0.0
1.473ArgAsn: 1.473 ± 1.055
8.837ArgPro: 8.837 ± 6.286
4.418ArgGln: 4.418 ± 3.164
20.619ArgArg: 20.619 ± 11.873
4.418ArgSer: 4.418 ± 1.582
5.891ArgThr: 5.891 ± 5.576
4.418ArgVal: 4.418 ± 2.757
4.418ArgTrp: 4.418 ± 2.217
1.473ArgTyr: 1.473 ± 0.976
0.0ArgXaa: 0.0 ± 0.0
Ser
2.946SerAla: 2.946 ± 2.197
2.946SerCys: 2.946 ± 3.919
2.946SerAsp: 2.946 ± 1.952
4.418SerGlu: 4.418 ± 2.928
1.473SerPhe: 1.473 ± 1.055
5.891SerGly: 5.891 ± 3.213
1.473SerHis: 1.473 ± 1.055
1.473SerIle: 1.473 ± 1.055
5.891SerLys: 5.891 ± 3.701
1.473SerLeu: 1.473 ± 1.055
1.473SerMet: 1.473 ± 1.823
5.891SerAsn: 5.891 ± 2.727
4.418SerPro: 4.418 ± 3.684
0.0SerGln: 0.0 ± 0.0
2.946SerArg: 2.946 ± 1.851
1.473SerSer: 1.473 ± 1.959
0.0SerThr: 0.0 ± 0.0
0.0SerVal: 0.0 ± 0.0
0.0SerTrp: 0.0 ± 0.0
1.473SerTyr: 1.473 ± 0.976
0.0SerXaa: 0.0 ± 0.0
Thr
1.473ThrAla: 1.473 ± 1.959
1.473ThrCys: 1.473 ± 1.959
7.364ThrAsp: 7.364 ± 3.675
5.891ThrGlu: 5.891 ± 2.883
1.473ThrPhe: 1.473 ± 1.055
5.891ThrGly: 5.891 ± 4.498
5.891ThrHis: 5.891 ± 1.483
4.418ThrIle: 4.418 ± 1.667
2.946ThrLys: 2.946 ± 0.868
2.946ThrLeu: 2.946 ± 1.807
0.0ThrMet: 0.0 ± 0.0
4.418ThrAsn: 4.418 ± 3.164
5.891ThrPro: 5.891 ± 1.483
0.0ThrGln: 0.0 ± 0.0
4.418ThrArg: 4.418 ± 3.051
5.891ThrSer: 5.891 ± 1.371
4.418ThrThr: 4.418 ± 2.288
1.473ThrVal: 1.473 ± 1.055
1.473ThrTrp: 1.473 ± 1.959
1.473ThrTyr: 1.473 ± 1.055
0.0ThrXaa: 0.0 ± 0.0
Val
2.946ValAla: 2.946 ± 1.952
0.0ValCys: 0.0 ± 0.0
1.473ValAsp: 1.473 ± 0.976
5.891ValGlu: 5.891 ± 1.736
2.946ValPhe: 2.946 ± 1.952
2.946ValGly: 2.946 ± 1.952
0.0ValHis: 0.0 ± 0.0
4.418ValIle: 4.418 ± 2.928
8.837ValLys: 8.837 ± 4.286
4.418ValLeu: 4.418 ± 1.582
0.0ValMet: 0.0 ± 0.0
1.473ValAsn: 1.473 ± 1.055
4.418ValPro: 4.418 ± 1.667
1.473ValGln: 1.473 ± 0.976
2.946ValArg: 2.946 ± 0.868
0.0ValSer: 0.0 ± 0.0
2.946ValThr: 2.946 ± 2.109
1.473ValVal: 1.473 ± 0.976
0.0ValTrp: 0.0 ± 0.0
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.473TrpAla: 1.473 ± 0.976
0.0TrpCys: 0.0 ± 0.0
4.418TrpAsp: 4.418 ± 1.517
1.473TrpGlu: 1.473 ± 1.959
0.0TrpPhe: 0.0 ± 0.0
2.946TrpGly: 2.946 ± 1.807
0.0TrpHis: 0.0 ± 0.0
2.946TrpIle: 2.946 ± 0.868
0.0TrpLys: 0.0 ± 0.0
2.946TrpLeu: 2.946 ± 0.868
0.0TrpMet: 0.0 ± 0.0
1.473TrpAsn: 1.473 ± 1.055
4.418TrpPro: 4.418 ± 4.896
2.946TrpGln: 2.946 ± 2.197
2.946TrpArg: 2.946 ± 2.109
1.473TrpSer: 1.473 ± 2.068
1.473TrpThr: 1.473 ± 1.055
1.473TrpVal: 1.473 ± 0.976
1.473TrpTrp: 1.473 ± 0.976
1.473TrpTyr: 1.473 ± 0.976
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.473TyrAla: 1.473 ± 0.976
2.946TyrCys: 2.946 ± 1.851
0.0TyrAsp: 0.0 ± 0.0
0.0TyrGlu: 0.0 ± 0.0
0.0TyrPhe: 0.0 ± 0.0
2.946TyrGly: 2.946 ± 0.868
1.473TyrHis: 1.473 ± 0.976
1.473TyrIle: 1.473 ± 1.055
1.473TyrLys: 1.473 ± 0.976
0.0TyrLeu: 0.0 ± 0.0
2.946TyrMet: 2.946 ± 1.007
0.0TyrAsn: 0.0 ± 0.0
2.946TyrPro: 2.946 ± 1.952
2.946TyrGln: 2.946 ± 2.109
2.946TyrArg: 2.946 ± 2.109
4.418TyrSer: 4.418 ± 2.217
0.0TyrThr: 0.0 ± 0.0
5.891TyrVal: 5.891 ± 2.398
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (680 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski