Amino acid dipepetide frequency for Maize-associated totivirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.541AlaAla: 9.541 ± 1.132
4.174AlaCys: 4.174 ± 1.391
2.385AlaAsp: 2.385 ± 1.096
2.385AlaGlu: 2.385 ± 0.007
2.982AlaPhe: 2.982 ± 0.836
5.367AlaGly: 5.367 ± 1.947
2.385AlaHis: 2.385 ± 0.007
4.77AlaIle: 4.77 ± 1.089
5.367AlaLys: 5.367 ± 1.363
5.963AlaLeu: 5.963 ± 0.533
4.174AlaMet: 4.174 ± 0.459
1.193AlaAsn: 1.193 ± 0.548
1.789AlaPro: 1.789 ± 1.384
4.174AlaGln: 4.174 ± 0.815
8.348AlaArg: 8.348 ± 0.577
4.174AlaSer: 4.174 ± 0.288
7.156AlaThr: 7.156 ± 1.081
5.963AlaVal: 5.963 ± 1.636
1.789AlaTrp: 1.789 ± 0.281
2.385AlaTyr: 2.385 ± 1.096
0.0AlaXaa: 0.0 ± 0.0
Cys
1.193CysAla: 1.193 ± 0.548
0.0CysCys: 0.0 ± 0.0
1.193CysAsp: 1.193 ± 0.548
2.982CysGlu: 2.982 ± 0.267
0.596CysPhe: 0.596 ± 0.274
0.0CysGly: 0.0 ± 0.0
1.193CysHis: 1.193 ± 0.555
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.789CysLeu: 1.789 ± 0.822
0.0CysMet: 0.0 ± 0.0
1.193CysAsn: 1.193 ± 0.548
1.789CysPro: 1.789 ± 0.281
2.385CysGln: 2.385 ± 1.11
0.596CysArg: 0.596 ± 0.274
0.0CysSer: 0.0 ± 0.0
1.193CysThr: 1.193 ± 0.555
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.596CysTyr: 0.596 ± 0.274
0.0CysXaa: 0.0 ± 0.0
Asp
4.174AspAla: 4.174 ± 1.391
0.0AspCys: 0.0 ± 0.0
4.77AspAsp: 4.77 ± 0.014
2.385AspGlu: 2.385 ± 0.007
4.77AspPhe: 4.77 ± 0.014
2.982AspGly: 2.982 ± 0.267
0.0AspHis: 0.0 ± 0.0
4.174AspIle: 4.174 ± 0.288
1.193AspLys: 1.193 ± 0.548
2.385AspLeu: 2.385 ± 1.096
1.193AspMet: 1.193 ± 0.548
3.578AspAsn: 3.578 ± 0.562
1.193AspPro: 1.193 ± 0.555
2.385AspGln: 2.385 ± 0.007
5.367AspArg: 5.367 ± 0.259
2.385AspSer: 2.385 ± 1.096
5.963AspThr: 5.963 ± 0.57
7.156AspVal: 7.156 ± 0.022
0.596AspTrp: 0.596 ± 0.274
0.596AspTyr: 0.596 ± 0.274
0.0AspXaa: 0.0 ± 0.0
Glu
4.174GluAla: 4.174 ± 0.815
0.0GluCys: 0.0 ± 0.0
5.963GluAsp: 5.963 ± 0.57
1.789GluGlu: 1.789 ± 0.822
2.385GluPhe: 2.385 ± 0.007
3.578GluGly: 3.578 ± 0.562
1.789GluHis: 1.789 ± 0.822
2.982GluIle: 2.982 ± 0.267
0.596GluLys: 0.596 ± 0.274
6.559GluLeu: 6.559 ± 0.296
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
1.193GluPro: 1.193 ± 0.548
1.789GluGln: 1.789 ± 0.281
4.77GluArg: 4.77 ± 1.089
3.578GluSer: 3.578 ± 0.562
1.193GluThr: 1.193 ± 0.555
5.963GluVal: 5.963 ± 0.533
1.193GluTrp: 1.193 ± 0.548
4.77GluTyr: 4.77 ± 1.118
0.0GluXaa: 0.0 ± 0.0
Phe
1.193PheAla: 1.193 ± 0.548
1.789PheCys: 1.789 ± 0.281
4.77PheAsp: 4.77 ± 0.014
5.963PheGlu: 5.963 ± 0.57
2.385PhePhe: 2.385 ± 1.11
0.596PheGly: 0.596 ± 0.274
1.193PheHis: 1.193 ± 0.548
1.193PheIle: 1.193 ± 0.555
5.367PheLys: 5.367 ± 0.844
4.77PheLeu: 4.77 ± 0.014
1.789PheMet: 1.789 ± 0.281
1.789PheAsn: 1.789 ± 0.281
1.789PhePro: 1.789 ± 0.281
2.982PheGln: 2.982 ± 0.836
1.789PheArg: 1.789 ± 1.384
1.789PheSer: 1.789 ± 0.822
0.0PheThr: 0.0 ± 0.0
4.77PheVal: 4.77 ± 0.014
0.0PheTrp: 0.0 ± 0.0
0.596PheTyr: 0.596 ± 0.274
0.0PheXaa: 0.0 ± 0.0
Gly
7.156GlyAla: 7.156 ± 1.125
1.193GlyCys: 1.193 ± 0.548
2.385GlyAsp: 2.385 ± 0.007
2.982GlyGlu: 2.982 ± 1.37
4.77GlyPhe: 4.77 ± 1.118
4.77GlyGly: 4.77 ± 1.118
0.0GlyHis: 0.0 ± 0.0
1.789GlyIle: 1.789 ± 0.822
4.174GlyLys: 4.174 ± 0.288
5.963GlyLeu: 5.963 ± 1.673
2.385GlyMet: 2.385 ± 1.11
0.596GlyAsn: 0.596 ± 0.274
1.789GlyPro: 1.789 ± 1.384
1.789GlyGln: 1.789 ± 0.281
4.77GlyArg: 4.77 ± 1.118
2.385GlySer: 2.385 ± 0.007
4.77GlyThr: 4.77 ± 1.118
6.559GlyVal: 6.559 ± 0.296
0.596GlyTrp: 0.596 ± 0.274
1.193GlyTyr: 1.193 ± 0.548
0.0GlyXaa: 0.0 ± 0.0
His
1.789HisAla: 1.789 ± 0.822
0.0HisCys: 0.0 ± 0.0
2.982HisAsp: 2.982 ± 0.836
1.193HisGlu: 1.193 ± 0.548
1.193HisPhe: 1.193 ± 0.555
1.193HisGly: 1.193 ± 0.548
1.193HisHis: 1.193 ± 0.548
0.596HisIle: 0.596 ± 0.274
0.596HisLys: 0.596 ± 0.274
1.789HisLeu: 1.789 ± 0.822
0.0HisMet: 0.0 ± 0.0
2.385HisAsn: 2.385 ± 0.007
0.0HisPro: 0.0 ± 0.0
0.596HisGln: 0.596 ± 0.274
2.982HisArg: 2.982 ± 1.37
1.789HisSer: 1.789 ± 0.822
2.385HisThr: 2.385 ± 0.007
3.578HisVal: 3.578 ± 0.562
0.0HisTrp: 0.0 ± 0.0
1.193HisTyr: 1.193 ± 0.548
0.0HisXaa: 0.0 ± 0.0
Ile
2.982IleAla: 2.982 ± 1.37
0.0IleCys: 0.0 ± 0.0
4.174IleAsp: 4.174 ± 0.288
1.193IleGlu: 1.193 ± 0.555
1.193IlePhe: 1.193 ± 0.548
2.385IleGly: 2.385 ± 0.007
3.578IleHis: 3.578 ± 0.541
1.193IleIle: 1.193 ± 0.548
1.193IleLys: 1.193 ± 0.548
1.789IleLeu: 1.789 ± 0.281
1.193IleMet: 1.193 ± 0.548
3.578IleAsn: 3.578 ± 0.562
3.578IlePro: 3.578 ± 0.562
0.596IleGln: 0.596 ± 0.274
3.578IleArg: 3.578 ± 0.541
5.963IleSer: 5.963 ± 0.57
2.982IleThr: 2.982 ± 0.267
2.982IleVal: 2.982 ± 1.37
2.385IleTrp: 2.385 ± 0.007
1.789IleTyr: 1.789 ± 0.281
0.0IleXaa: 0.0 ± 0.0
Lys
2.385LysAla: 2.385 ± 1.096
0.596LysCys: 0.596 ± 0.274
1.789LysAsp: 1.789 ± 0.822
4.174LysGlu: 4.174 ± 0.288
1.789LysPhe: 1.789 ± 0.281
1.789LysGly: 1.789 ± 0.281
1.789LysHis: 1.789 ± 0.822
6.559LysIle: 6.559 ± 0.296
1.193LysLys: 1.193 ± 0.555
0.0LysLeu: 0.0 ± 0.0
1.193LysMet: 1.193 ± 0.548
1.789LysAsn: 1.789 ± 0.281
0.596LysPro: 0.596 ± 0.274
3.578LysGln: 3.578 ± 0.562
1.193LysArg: 1.193 ± 0.548
4.77LysSer: 4.77 ± 1.118
3.578LysThr: 3.578 ± 0.541
1.193LysVal: 1.193 ± 0.548
0.0LysTrp: 0.0 ± 0.0
3.578LysTyr: 3.578 ± 0.541
0.0LysXaa: 0.0 ± 0.0
Leu
6.559LeuAla: 6.559 ± 1.399
0.0LeuCys: 0.0 ± 0.0
3.578LeuAsp: 3.578 ± 0.541
4.174LeuGlu: 4.174 ± 0.288
1.789LeuPhe: 1.789 ± 0.281
4.77LeuGly: 4.77 ± 0.014
0.596LeuHis: 0.596 ± 0.274
0.0LeuIle: 0.0 ± 0.0
5.367LeuLys: 5.367 ± 0.844
7.752LeuLeu: 7.752 ± 0.851
2.385LeuMet: 2.385 ± 0.262
3.578LeuAsn: 3.578 ± 0.541
7.752LeuPro: 7.752 ± 1.954
1.789LeuGln: 1.789 ± 0.281
8.348LeuArg: 8.348 ± 0.577
3.578LeuSer: 3.578 ± 0.541
7.156LeuThr: 7.156 ± 1.081
4.77LeuVal: 4.77 ± 2.192
0.0LeuTrp: 0.0 ± 0.0
2.385LeuTyr: 2.385 ± 0.007
0.0LeuXaa: 0.0 ± 0.0
Met
1.789MetAla: 1.789 ± 0.281
0.0MetCys: 0.0 ± 0.0
2.982MetAsp: 2.982 ± 0.836
0.0MetGlu: 0.0 ± 0.0
1.193MetPhe: 1.193 ± 0.548
2.982MetGly: 2.982 ± 0.836
1.789MetHis: 1.789 ± 0.281
1.193MetIle: 1.193 ± 0.555
1.193MetLys: 1.193 ± 0.555
3.578MetLeu: 3.578 ± 0.562
0.596MetMet: 0.596 ± 0.274
2.982MetAsn: 2.982 ± 0.836
0.596MetPro: 0.596 ± 0.274
0.596MetGln: 0.596 ± 0.274
0.0MetArg: 0.0 ± 0.0
1.789MetSer: 1.789 ± 0.822
1.789MetThr: 1.789 ± 0.281
0.596MetVal: 0.596 ± 0.274
0.0MetTrp: 0.0 ± 0.0
1.789MetTyr: 1.789 ± 0.822
0.0MetXaa: 0.0 ± 0.0
Asn
1.789AsnAla: 1.789 ± 0.822
0.0AsnCys: 0.0 ± 0.0
1.193AsnAsp: 1.193 ± 0.555
3.578AsnGlu: 3.578 ± 0.562
1.789AsnPhe: 1.789 ± 0.281
1.789AsnGly: 1.789 ± 0.281
2.385AsnHis: 2.385 ± 0.007
3.578AsnIle: 3.578 ± 0.541
0.0AsnLys: 0.0 ± 0.0
1.789AsnLeu: 1.789 ± 0.281
4.174AsnMet: 4.174 ± 1.391
1.193AsnAsn: 1.193 ± 0.555
0.0AsnPro: 0.0 ± 0.0
1.193AsnGln: 1.193 ± 0.555
1.193AsnArg: 1.193 ± 0.548
0.596AsnSer: 0.596 ± 0.274
0.596AsnThr: 0.596 ± 0.274
3.578AsnVal: 3.578 ± 1.644
0.0AsnTrp: 0.0 ± 0.0
4.77AsnTyr: 4.77 ± 1.118
0.0AsnXaa: 0.0 ± 0.0
Pro
4.77ProAla: 4.77 ± 1.118
0.596ProCys: 0.596 ± 0.274
2.385ProAsp: 2.385 ± 1.11
5.963ProGlu: 5.963 ± 0.57
3.578ProPhe: 3.578 ± 1.665
5.963ProGly: 5.963 ± 0.57
1.193ProHis: 1.193 ± 0.548
3.578ProIle: 3.578 ± 0.541
0.0ProLys: 0.0 ± 0.0
4.77ProLeu: 4.77 ± 1.118
1.193ProMet: 1.193 ± 0.555
0.0ProAsn: 0.0 ± 0.0
4.174ProPro: 4.174 ± 0.288
0.596ProGln: 0.596 ± 0.274
1.193ProArg: 1.193 ± 0.555
0.0ProSer: 0.0 ± 0.0
4.174ProThr: 4.174 ± 0.288
4.174ProVal: 4.174 ± 1.391
0.0ProTrp: 0.0 ± 0.0
1.789ProTyr: 1.789 ± 0.281
0.0ProXaa: 0.0 ± 0.0
Gln
6.559GlnAla: 6.559 ± 0.296
3.578GlnCys: 3.578 ± 0.562
3.578GlnAsp: 3.578 ± 0.562
4.174GlnGlu: 4.174 ± 1.391
0.0GlnPhe: 0.0 ± 0.0
1.789GlnGly: 1.789 ± 0.281
2.385GlnHis: 2.385 ± 1.096
1.789GlnIle: 1.789 ± 0.822
1.193GlnLys: 1.193 ± 0.548
1.193GlnLeu: 1.193 ± 0.555
0.0GlnMet: 0.0 ± 0.0
1.193GlnAsn: 1.193 ± 0.555
2.385GlnPro: 2.385 ± 0.007
1.789GlnGln: 1.789 ± 0.281
1.193GlnArg: 1.193 ± 0.548
3.578GlnSer: 3.578 ± 1.665
1.193GlnThr: 1.193 ± 0.555
0.596GlnVal: 0.596 ± 0.274
0.0GlnTrp: 0.0 ± 0.0
1.789GlnTyr: 1.789 ± 0.822
0.0GlnXaa: 0.0 ± 0.0
Arg
7.752ArgAla: 7.752 ± 1.355
2.982ArgCys: 2.982 ± 1.37
3.578ArgAsp: 3.578 ± 0.562
1.789ArgGlu: 1.789 ± 0.822
4.77ArgPhe: 4.77 ± 1.118
8.348ArgGly: 8.348 ± 2.783
1.193ArgHis: 1.193 ± 0.555
2.982ArgIle: 2.982 ± 0.836
4.174ArgLys: 4.174 ± 1.918
2.982ArgLeu: 2.982 ± 0.836
0.596ArgMet: 0.596 ± 0.274
2.982ArgAsn: 2.982 ± 1.37
3.578ArgPro: 3.578 ± 0.541
4.174ArgGln: 4.174 ± 0.815
7.156ArgArg: 7.156 ± 0.022
2.385ArgSer: 2.385 ± 1.096
2.982ArgThr: 2.982 ± 0.267
6.559ArgVal: 6.559 ± 0.296
0.596ArgTrp: 0.596 ± 0.274
4.174ArgTyr: 4.174 ± 0.288
0.0ArgXaa: 0.0 ± 0.0
Ser
5.367SerAla: 5.367 ± 0.844
1.193SerCys: 1.193 ± 0.548
2.385SerAsp: 2.385 ± 1.096
0.0SerGlu: 0.0 ± 0.0
1.193SerPhe: 1.193 ± 0.548
1.789SerGly: 1.789 ± 0.281
0.0SerHis: 0.0 ± 0.0
2.385SerIle: 2.385 ± 0.007
4.174SerLys: 4.174 ± 1.391
1.193SerLeu: 1.193 ± 0.548
2.982SerMet: 2.982 ± 0.267
4.174SerAsn: 4.174 ± 1.391
1.193SerPro: 1.193 ± 0.548
1.789SerGln: 1.789 ± 0.822
3.578SerArg: 3.578 ± 1.644
2.982SerSer: 2.982 ± 0.836
4.174SerThr: 4.174 ± 0.288
4.77SerVal: 4.77 ± 1.089
2.982SerTrp: 2.982 ± 0.267
2.385SerTyr: 2.385 ± 1.11
0.0SerXaa: 0.0 ± 0.0
Thr
4.174ThrAla: 4.174 ± 0.815
0.0ThrCys: 0.0 ± 0.0
0.596ThrAsp: 0.596 ± 0.274
4.174ThrGlu: 4.174 ± 0.815
4.77ThrPhe: 4.77 ± 0.014
4.174ThrGly: 4.174 ± 0.288
0.596ThrHis: 0.596 ± 0.274
1.789ThrIle: 1.789 ± 0.281
2.385ThrLys: 2.385 ± 0.007
7.156ThrLeu: 7.156 ± 0.022
1.789ThrMet: 1.789 ± 0.281
0.596ThrAsn: 0.596 ± 0.274
7.156ThrPro: 7.156 ± 1.125
2.385ThrGln: 2.385 ± 0.007
6.559ThrArg: 6.559 ± 0.296
3.578ThrSer: 3.578 ± 0.541
4.77ThrThr: 4.77 ± 1.089
6.559ThrVal: 6.559 ± 1.399
2.982ThrTrp: 2.982 ± 0.836
2.385ThrTyr: 2.385 ± 1.11
0.0ThrXaa: 0.0 ± 0.0
Val
9.541ValAla: 9.541 ± 0.029
0.596ValCys: 0.596 ± 0.274
3.578ValAsp: 3.578 ± 1.644
2.982ValGlu: 2.982 ± 0.267
2.982ValPhe: 2.982 ± 1.37
5.367ValGly: 5.367 ± 1.363
1.789ValHis: 1.789 ± 0.822
5.367ValIle: 5.367 ± 0.259
3.578ValLys: 3.578 ± 1.644
9.541ValLeu: 9.541 ± 0.029
1.193ValMet: 1.193 ± 0.555
2.385ValAsn: 2.385 ± 0.007
5.963ValPro: 5.963 ± 1.673
0.596ValGln: 0.596 ± 0.274
5.367ValArg: 5.367 ± 0.844
2.385ValSer: 2.385 ± 1.096
9.541ValThr: 9.541 ± 1.132
4.77ValVal: 4.77 ± 0.014
1.193ValTrp: 1.193 ± 0.548
0.596ValTyr: 0.596 ± 0.274
0.0ValXaa: 0.0 ± 0.0
Trp
1.193TrpAla: 1.193 ± 0.548
0.0TrpCys: 0.0 ± 0.0
0.596TrpAsp: 0.596 ± 0.274
0.596TrpGlu: 0.596 ± 0.274
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
1.193TrpHis: 1.193 ± 0.555
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.193TrpLeu: 1.193 ± 0.548
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
1.193TrpPro: 1.193 ± 0.555
1.193TrpGln: 1.193 ± 0.555
3.578TrpArg: 3.578 ± 0.541
0.596TrpSer: 0.596 ± 0.274
1.789TrpThr: 1.789 ± 0.281
1.193TrpVal: 1.193 ± 0.548
0.596TrpTrp: 0.596 ± 0.274
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.982TyrAla: 2.982 ± 0.267
0.0TyrCys: 0.0 ± 0.0
2.385TyrAsp: 2.385 ± 0.007
1.789TyrGlu: 1.789 ± 0.822
2.385TyrPhe: 2.385 ± 0.007
2.385TyrGly: 2.385 ± 0.007
1.193TyrHis: 1.193 ± 0.548
2.385TyrIle: 2.385 ± 1.096
1.789TyrLys: 1.789 ± 0.281
4.174TyrLeu: 4.174 ± 0.815
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
2.385TyrPro: 2.385 ± 0.007
3.578TyrGln: 3.578 ± 1.665
4.174TyrArg: 4.174 ± 0.815
2.385TyrSer: 2.385 ± 1.11
1.193TyrThr: 1.193 ± 0.555
3.578TyrVal: 3.578 ± 0.562
0.0TyrTrp: 0.0 ± 0.0
0.596TyrTyr: 0.596 ± 0.274
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1678 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski