Amino acid dipepetide frequency for Ziziphus jujuba (Chinese jujube) (Ziziphus sativa)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.699AlaAla: 5.699 ± 0.026	1.234AlaCys: 1.234 ± 0.01	2.969AlaAsp: 2.969 ± 0.016	3.964AlaGlu: 3.964 ± 0.018	2.799AlaPhe: 2.799 ± 0.016	3.847AlaGly: 3.847 ± 0.018	1.268AlaHis: 1.268 ± 0.01	3.768AlaIle: 3.768 ± 0.016	3.799AlaLys: 3.799 ± 0.018	6.455AlaLeu: 6.455 ± 0.025	1.697AlaMet: 1.697 ± 0.011	2.612AlaAsn: 2.612 ± 0.014	2.477AlaPro: 2.477 ± 0.016	1.997AlaGln: 1.997 ± 0.012	3.102AlaArg: 3.102 ± 0.014	5.788AlaSer: 5.788 ± 0.022	3.333AlaThr: 3.333 ± 0.017	4.573AlaVal: 4.573 ± 0.018	0.752AlaTrp: 0.752 ± 0.008	1.847AlaTyr: 1.847 ± 0.011	0.003AlaXaa: 0.003 ± 0.0
Cys	0.939CysAla: 0.939 ± 0.008	0.554CysCys: 0.554 ± 0.006	0.86CysAsp: 0.86 ± 0.008	0.935CysGlu: 0.935 ± 0.01	0.953CysPhe: 0.953 ± 0.008	1.448CysGly: 1.448 ± 0.011	0.484CysHis: 0.484 ± 0.006	1.065CysIle: 1.065 ± 0.01	1.213CysLys: 1.213 ± 0.012	1.978CysLeu: 1.978 ± 0.013	0.452CysMet: 0.452 ± 0.005	0.92CysAsn: 0.92 ± 0.007	0.95CysPro: 0.95 ± 0.009	0.646CysGln: 0.646 ± 0.007	1.047CysArg: 1.047 ± 0.009	1.911CysSer: 1.911 ± 0.014	0.863CysThr: 0.863 ± 0.008	1.006CysVal: 1.006 ± 0.009	0.249CysTrp: 0.249 ± 0.004	0.558CysTyr: 0.558 ± 0.007	0.001CysXaa: 0.001 ± 0.0
Asp	3.31AspAla: 3.31 ± 0.019	1.001AspCys: 1.001 ± 0.009	3.595AspAsp: 3.595 ± 0.022	3.9AspGlu: 3.9 ± 0.019	2.384AspPhe: 2.384 ± 0.011	3.783AspGly: 3.783 ± 0.018	1.304AspHis: 1.304 ± 0.009	3.134AspIle: 3.134 ± 0.016	2.779AspLys: 2.779 ± 0.016	5.207AspLeu: 5.207 ± 0.025	1.315AspMet: 1.315 ± 0.01	2.196AspAsn: 2.196 ± 0.014	2.473AspPro: 2.473 ± 0.013	1.788AspGln: 1.788 ± 0.012	2.327AspArg: 2.327 ± 0.016	4.23AspSer: 4.23 ± 0.019	2.13AspThr: 2.13 ± 0.013	3.614AspVal: 3.614 ± 0.016	0.715AspTrp: 0.715 ± 0.006	1.554AspTyr: 1.554 ± 0.011	0.003AspXaa: 0.003 ± 0.0
Glu	4.64GluAla: 4.64 ± 0.021	0.948GluCys: 0.948 ± 0.008	3.931GluAsp: 3.931 ± 0.02	6.089GluGlu: 6.089 ± 0.033	2.42GluPhe: 2.42 ± 0.013	3.623GluGly: 3.623 ± 0.016	1.264GluHis: 1.264 ± 0.009	4.009GluIle: 4.009 ± 0.022	4.812GluLys: 4.812 ± 0.022	6.155GluLeu: 6.155 ± 0.025	1.755GluMet: 1.755 ± 0.012	3.314GluAsn: 3.314 ± 0.015	2.011GluPro: 2.011 ± 0.013	2.092GluGln: 2.092 ± 0.013	3.301GluArg: 3.301 ± 0.018	4.606GluSer: 4.606 ± 0.02	3.05GluThr: 3.05 ± 0.016	4.107GluVal: 4.107 ± 0.018	0.772GluTrp: 0.772 ± 0.007	1.705GluTyr: 1.705 ± 0.012	0.003GluXaa: 0.003 ± 0.0
Phe	2.457PheAla: 2.457 ± 0.013	0.946PheCys: 0.946 ± 0.008	2.37PheAsp: 2.37 ± 0.013	2.363PheGlu: 2.363 ± 0.013	2.043PhePhe: 2.043 ± 0.017	3.164PheGly: 3.164 ± 0.017	1.183PheHis: 1.183 ± 0.009	2.227PheIle: 2.227 ± 0.013	2.211PheLys: 2.211 ± 0.012	4.505PheLeu: 4.505 ± 0.023	0.971PheMet: 0.971 ± 0.008	1.896PheAsn: 1.896 ± 0.013	2.231PhePro: 2.231 ± 0.015	1.651PheGln: 1.651 ± 0.01	2.009PheArg: 2.009 ± 0.012	4.239PheSer: 4.239 ± 0.02	2.022PheThr: 2.022 ± 0.01	2.741PheVal: 2.741 ± 0.014	0.579PheTrp: 0.579 ± 0.006	1.305PheTyr: 1.305 ± 0.009	0.003PheXaa: 0.003 ± 0.0
Gly	3.526GlyAla: 3.526 ± 0.019	1.384GlyCys: 1.384 ± 0.013	3.301GlyAsp: 3.301 ± 0.016	3.546GlyGlu: 3.546 ± 0.017	3.242GlyPhe: 3.242 ± 0.015	5.179GlyGly: 5.179 ± 0.034	1.513GlyHis: 1.513 ± 0.011	3.771GlyIle: 3.771 ± 0.018	4.204GlyLys: 4.204 ± 0.018	6.044GlyLeu: 6.044 ± 0.022	1.512GlyMet: 1.512 ± 0.012	3.383GlyAsn: 3.383 ± 0.019	2.331GlyPro: 2.331 ± 0.014	2.094GlyGln: 2.094 ± 0.012	3.438GlyArg: 3.438 ± 0.017	5.955GlySer: 5.955 ± 0.027	3.194GlyThr: 3.194 ± 0.016	4.046GlyVal: 4.046 ± 0.02	0.903GlyTrp: 0.903 ± 0.008	2.125GlyTyr: 2.125 ± 0.014	0.003GlyXaa: 0.003 ± 0.0
His	1.408HisAla: 1.408 ± 0.009	0.545HisCys: 0.545 ± 0.006	1.209HisAsp: 1.209 ± 0.009	1.3HisGlu: 1.3 ± 0.01	1.105HisPhe: 1.105 ± 0.009	1.807HisGly: 1.807 ± 0.011	1.055HisHis: 1.055 ± 0.015	1.31HisIle: 1.31 ± 0.009	1.196HisLys: 1.196 ± 0.01	2.616HisLeu: 2.616 ± 0.016	0.539HisMet: 0.539 ± 0.005	1.042HisAsn: 1.042 ± 0.009	1.32HisPro: 1.32 ± 0.012	1.037HisGln: 1.037 ± 0.009	1.341HisArg: 1.341 ± 0.008	1.924HisSer: 1.924 ± 0.011	0.955HisThr: 0.955 ± 0.008	1.537HisVal: 1.537 ± 0.011	0.299HisTrp: 0.299 ± 0.004	0.726HisTyr: 0.726 ± 0.006	0.001HisXaa: 0.001 ± 0.0
Ile	3.617IleAla: 3.617 ± 0.017	1.149IleCys: 1.149 ± 0.01	2.942IleAsp: 2.942 ± 0.012	3.33IleGlu: 3.33 ± 0.015	2.418IlePhe: 2.418 ± 0.013	3.613IleGly: 3.613 ± 0.016	1.381IleHis: 1.381 ± 0.01	2.983IleIle: 2.983 ± 0.016	3.085IleLys: 3.085 ± 0.016	5.489IleLeu: 5.489 ± 0.021	1.131IleMet: 1.131 ± 0.009	2.349IleAsn: 2.349 ± 0.014	3.246IlePro: 3.246 ± 0.024	2.046IleGln: 2.046 ± 0.012	2.629IleArg: 2.629 ± 0.015	5.223IleSer: 5.223 ± 0.022	2.604IleThr: 2.604 ± 0.014	3.522IleVal: 3.522 ± 0.016	0.751IleTrp: 0.751 ± 0.008	1.654IleTyr: 1.654 ± 0.012	0.003IleXaa: 0.003 ± 0.0
Lys	3.935LysAla: 3.935 ± 0.018	1.032LysCys: 1.032 ± 0.009	3.372LysAsp: 3.372 ± 0.013	4.755LysGlu: 4.755 ± 0.024	2.312LysPhe: 2.312 ± 0.012	3.578LysGly: 3.578 ± 0.017	1.386LysHis: 1.386 ± 0.009	3.431LysIle: 3.431 ± 0.016	4.697LysLys: 4.697 ± 0.025	6.454LysLeu: 6.454 ± 0.027	1.536LysMet: 1.536 ± 0.011	2.893LysAsn: 2.893 ± 0.015	2.716LysPro: 2.716 ± 0.018	2.308LysGln: 2.308 ± 0.012	3.489LysArg: 3.489 ± 0.019	4.715LysSer: 4.715 ± 0.019	2.871LysThr: 2.871 ± 0.014	3.858LysVal: 3.858 ± 0.017	0.817LysTrp: 0.817 ± 0.006	1.663LysTyr: 1.663 ± 0.011	0.002LysXaa: 0.002 ± 0.0
Leu	6.381LeuAla: 6.381 ± 0.024	1.916LeuCys: 1.916 ± 0.011	5.413LeuAsp: 5.413 ± 0.02	6.753LeuGlu: 6.753 ± 0.027	3.994LeuPhe: 3.994 ± 0.019	5.878LeuGly: 5.878 ± 0.023	2.751LeuHis: 2.751 ± 0.015	4.795LeuIle: 4.795 ± 0.02	6.577LeuLys: 6.577 ± 0.028	10.035LeuLeu: 10.035 ± 0.031	2.101LeuMet: 2.101 ± 0.012	4.268LeuAsn: 4.268 ± 0.019	5.374LeuPro: 5.374 ± 0.024	4.535LeuGln: 4.535 ± 0.019	5.513LeuArg: 5.513 ± 0.022	9.303LeuSer: 9.303 ± 0.041	4.622LeuThr: 4.622 ± 0.023	6.427LeuVal: 6.427 ± 0.021	1.198LeuTrp: 1.198 ± 0.01	2.617LeuTyr: 2.617 ± 0.015	0.005LeuXaa: 0.005 ± 0.001
Met	2.03MetAla: 2.03 ± 0.011	0.321MetCys: 0.321 ± 0.005	1.431MetAsp: 1.431 ± 0.01	2.05MetGlu: 2.05 ± 0.012	0.806MetPhe: 0.806 ± 0.007	1.589MetGly: 1.589 ± 0.011	0.566MetHis: 0.566 ± 0.006	1.175MetIle: 1.175 ± 0.009	1.638MetLys: 1.638 ± 0.011	2.188MetLeu: 2.188 ± 0.013	0.646MetMet: 0.646 ± 0.007	1.016MetAsn: 1.016 ± 0.008	1.021MetPro: 1.021 ± 0.008	0.881MetGln: 0.881 ± 0.008	1.142MetArg: 1.142 ± 0.009	1.685MetSer: 1.685 ± 0.011	0.979MetThr: 0.979 ± 0.008	1.69MetVal: 1.69 ± 0.009	0.271MetTrp: 0.271 ± 0.005	0.574MetTyr: 0.574 ± 0.007	0.001MetXaa: 0.001 ± 0.0
Asn	2.676AsnAla: 2.676 ± 0.013	0.975AsnCys: 0.975 ± 0.01	2.196AsnAsp: 2.196 ± 0.011	2.665AsnGlu: 2.665 ± 0.015	2.139AsnPhe: 2.139 ± 0.013	3.417AsnGly: 3.417 ± 0.019	1.216AsnHis: 1.216 ± 0.01	2.737AsnIle: 2.737 ± 0.014	2.564AsnLys: 2.564 ± 0.015	5.421AsnLeu: 5.421 ± 0.033	1.171AsnMet: 1.171 ± 0.009	2.722AsnAsn: 2.722 ± 0.02	2.318AsnPro: 2.318 ± 0.017	1.797AsnGln: 1.797 ± 0.012	2.045AsnArg: 2.045 ± 0.011	4.155AsnSer: 4.155 ± 0.017	1.979AsnThr: 1.979 ± 0.011	2.811AsnVal: 2.811 ± 0.013	0.603AsnTrp: 0.603 ± 0.007	1.363AsnTyr: 1.363 ± 0.011	0.002AsnXaa: 0.002 ± 0.0
Pro	2.753ProAla: 2.753 ± 0.015	0.769ProCys: 0.769 ± 0.008	2.407ProAsp: 2.407 ± 0.014	3.053ProGlu: 3.053 ± 0.018	2.03ProPhe: 2.03 ± 0.011	2.488ProGly: 2.488 ± 0.013	1.101ProHis: 1.101 ± 0.008	2.398ProIle: 2.398 ± 0.012	2.729ProLys: 2.729 ± 0.016	4.281ProLeu: 4.281 ± 0.017	0.893ProMet: 0.893 ± 0.008	2.451ProAsn: 2.451 ± 0.014	3.648ProPro: 3.648 ± 0.042	1.803ProGln: 1.803 ± 0.013	2.153ProArg: 2.153 ± 0.012	5.134ProSer: 5.134 ± 0.024	2.533ProThr: 2.533 ± 0.015	2.905ProVal: 2.905 ± 0.014	0.574ProTrp: 0.574 ± 0.006	1.323ProTyr: 1.323 ± 0.013	0.003ProXaa: 0.003 ± 0.0
Gln	2.249GlnAla: 2.249 ± 0.014	0.579GlnCys: 0.579 ± 0.006	1.653GlnAsp: 1.653 ± 0.01	2.352GlnGlu: 2.352 ± 0.016	1.442GlnPhe: 1.442 ± 0.009	2.059GlnGly: 2.059 ± 0.012	0.945GlnHis: 0.945 ± 0.008	2.111GlnIle: 2.111 ± 0.013	2.355GlnLys: 2.355 ± 0.013	3.871GlnLeu: 3.871 ± 0.018	0.943GlnMet: 0.943 ± 0.008	1.946GlnAsn: 1.946 ± 0.013	1.667GlnPro: 1.667 ± 0.013	2.169GlnGln: 2.169 ± 0.032	2.043GlnArg: 2.043 ± 0.011	2.88GlnSer: 2.88 ± 0.017	1.777GlnThr: 1.777 ± 0.011	2.366GlnVal: 2.366 ± 0.013	0.455GlnTrp: 0.455 ± 0.006	0.94GlnTyr: 0.94 ± 0.008	0.001GlnXaa: 0.001 ± 0.0
Arg	2.94ArgAla: 2.94 ± 0.017	0.978ArgCys: 0.978 ± 0.009	2.566ArgAsp: 2.566 ± 0.016	3.168ArgGlu: 3.168 ± 0.019	2.189ArgPhe: 2.189 ± 0.013	3.019ArgGly: 3.019 ± 0.018	1.241ArgHis: 1.241 ± 0.011	2.912ArgIle: 2.912 ± 0.014	3.723ArgLys: 3.723 ± 0.019	5.056ArgLeu: 5.056 ± 0.019	1.266ArgMet: 1.266 ± 0.009	2.574ArgAsn: 2.574 ± 0.011	2.153ArgPro: 2.153 ± 0.013	1.752ArgGln: 1.752 ± 0.012	3.633ArgArg: 3.633 ± 0.022	4.196ArgSer: 4.196 ± 0.024	2.362ArgThr: 2.362 ± 0.013	3.08ArgVal: 3.08 ± 0.014	0.703ArgTrp: 0.703 ± 0.007	1.473ArgTyr: 1.473 ± 0.009	0.002ArgXaa: 0.002 ± 0.0
Ser	5.121SerAla: 5.121 ± 0.017	1.742SerCys: 1.742 ± 0.013	4.408SerAsp: 4.408 ± 0.021	4.857SerGlu: 4.857 ± 0.024	4.188SerPhe: 4.188 ± 0.018	5.934SerGly: 5.934 ± 0.024	2.058SerHis: 2.058 ± 0.012	4.92SerIle: 4.92 ± 0.021	5.107SerLys: 5.107 ± 0.022	9.398SerLeu: 9.398 ± 0.035	2.11SerMet: 2.11 ± 0.012	4.407SerAsn: 4.407 ± 0.021	4.294SerPro: 4.294 ± 0.03	3.063SerGln: 3.063 ± 0.018	4.303SerArg: 4.303 ± 0.021	11.518SerSer: 11.518 ± 0.054	4.677SerThr: 4.677 ± 0.019	5.166SerVal: 5.166 ± 0.022	1.2SerTrp: 1.2 ± 0.01	2.409SerTyr: 2.409 ± 0.014	0.004SerXaa: 0.004 ± 0.001
Thr	3.253ThrAla: 3.253 ± 0.015	0.898ThrCys: 0.898 ± 0.009	2.204ThrAsp: 2.204 ± 0.012	2.728ThrGlu: 2.728 ± 0.017	2.072ThrPhe: 2.072 ± 0.012	3.216ThrGly: 3.216 ± 0.017	1.028ThrHis: 1.028 ± 0.009	2.792ThrIle: 2.792 ± 0.016	2.688ThrLys: 2.688 ± 0.014	4.713ThrLeu: 4.713 ± 0.019	1.159ThrMet: 1.159 ± 0.009	2.152ThrAsn: 2.152 ± 0.012	2.383ThrPro: 2.383 ± 0.014	1.518ThrGln: 1.518 ± 0.011	2.23ThrArg: 2.23 ± 0.012	4.664ThrSer: 4.664 ± 0.021	3.037ThrThr: 3.037 ± 0.018	3.178ThrVal: 3.178 ± 0.016	0.623ThrTrp: 0.623 ± 0.007	1.357ThrTyr: 1.357 ± 0.01	0.001ThrXaa: 0.001 ± 0.0
Val	4.558ValAla: 4.558 ± 0.02	1.148ValCys: 1.148 ± 0.009	3.682ValAsp: 3.682 ± 0.017	4.399ValGlu: 4.399 ± 0.018	2.685ValPhe: 2.685 ± 0.013	4.139ValGly: 4.139 ± 0.021	1.502ValHis: 1.502 ± 0.012	3.352ValIle: 3.352 ± 0.019	3.868ValLys: 3.868 ± 0.017	6.349ValLeu: 6.349 ± 0.022	1.422ValMet: 1.422 ± 0.009	2.64ValAsn: 2.64 ± 0.014	3.058ValPro: 3.058 ± 0.016	2.248ValGln: 2.248 ± 0.011	3.014ValArg: 3.014 ± 0.016	5.435ValSer: 5.435 ± 0.023	3.002ValThr: 3.002 ± 0.015	4.805ValVal: 4.805 ± 0.021	0.746ValTrp: 0.746 ± 0.007	1.971ValTyr: 1.971 ± 0.013	0.003ValXaa: 0.003 ± 0.0
Trp	0.719TrpAla: 0.719 ± 0.008	0.243TrpCys: 0.243 ± 0.004	0.707TrpAsp: 0.707 ± 0.008	0.759TrpGlu: 0.759 ± 0.007	0.551TrpPhe: 0.551 ± 0.007	0.724TrpGly: 0.724 ± 0.008	0.293TrpHis: 0.293 ± 0.004	0.727TrpIle: 0.727 ± 0.007	0.983TrpLys: 0.983 ± 0.008	1.272TrpLeu: 1.272 ± 0.009	0.344TrpMet: 0.344 ± 0.004	0.778TrpAsn: 0.778 ± 0.008	0.483TrpPro: 0.483 ± 0.005	0.442TrpGln: 0.442 ± 0.005	0.809TrpArg: 0.809 ± 0.007	0.978TrpSer: 0.978 ± 0.008	0.646TrpThr: 0.646 ± 0.008	0.82TrpVal: 0.82 ± 0.009	0.234TrpTrp: 0.234 ± 0.004	0.338TrpTyr: 0.338 ± 0.005	0.001TrpXaa: 0.001 ± 0.0
Tyr	1.771TyrAla: 1.771 ± 0.011	0.672TyrCys: 0.672 ± 0.007	1.526TyrAsp: 1.526 ± 0.01	1.637TyrGlu: 1.637 ± 0.011	1.341TyrPhe: 1.341 ± 0.01	2.185TyrGly: 2.185 ± 0.013	0.73TyrHis: 0.73 ± 0.008	1.542TyrIle: 1.542 ± 0.011	1.589TyrLys: 1.589 ± 0.012	2.964TyrLeu: 2.964 ± 0.016	0.737TyrMet: 0.737 ± 0.007	1.409TyrAsn: 1.409 ± 0.011	1.272TyrPro: 1.272 ± 0.01	0.933TyrGln: 0.933 ± 0.008	1.415TyrArg: 1.415 ± 0.009	2.338TyrSer: 2.338 ± 0.014	1.258TyrThr: 1.258 ± 0.01	1.772TyrVal: 1.772 ± 0.012	0.407TyrTrp: 0.407 ± 0.005	0.979TyrTyr: 0.979 ± 0.009	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.002XaaAsp: 0.002 ± 0.0	0.003XaaGlu: 0.003 ± 0.0	0.003XaaPhe: 0.003 ± 0.0	0.003XaaGly: 0.003 ± 0.0	0.001XaaHis: 0.001 ± 0.0	0.003XaaIle: 0.003 ± 0.0	0.003XaaLys: 0.003 ± 0.0	0.005XaaLeu: 0.005 ± 0.001	0.001XaaMet: 0.001 ± 0.0	0.002XaaAsn: 0.002 ± 0.0	0.002XaaPro: 0.002 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.002XaaArg: 0.002 ± 0.0	0.004XaaSer: 0.004 ± 0.001	0.002XaaThr: 0.002 ± 0.0	0.003XaaVal: 0.003 ± 0.001	0.001XaaTrp: 0.001 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.041XaaXaa: 0.041 ± 0.006

Statistics based on 34600 proteins (15613593 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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