Amino acid dipepetide frequency for Dahlia mosaic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.582AlaAla: 2.582 ± 1.191
0.861AlaCys: 0.861 ± 0.684
3.012AlaAsp: 3.012 ± 1.049
2.582AlaGlu: 2.582 ± 1.06
2.151AlaPhe: 2.151 ± 0.879
1.291AlaGly: 1.291 ± 0.676
0.861AlaHis: 0.861 ± 0.51
2.151AlaIle: 2.151 ± 0.657
3.442AlaLys: 3.442 ± 0.709
4.733AlaLeu: 4.733 ± 1.927
2.151AlaMet: 2.151 ± 0.582
3.442AlaAsn: 3.442 ± 1.033
1.291AlaPro: 1.291 ± 0.674
2.151AlaGln: 2.151 ± 0.465
1.291AlaArg: 1.291 ± 1.031
5.164AlaSer: 5.164 ± 1.229
2.151AlaThr: 2.151 ± 0.907
1.291AlaVal: 1.291 ± 0.662
0.0AlaTrp: 0.0 ± 0.0
2.151AlaTyr: 2.151 ± 0.956
0.0AlaXaa: 0.0 ± 0.0
Cys
0.861CysAla: 0.861 ± 0.585
0.43CysCys: 0.43 ± 0.344
1.291CysAsp: 1.291 ± 0.801
1.291CysGlu: 1.291 ± 0.629
0.0CysPhe: 0.0 ± 0.0
0.43CysGly: 0.43 ± 0.409
0.0CysHis: 0.0 ± 0.0
1.291CysIle: 1.291 ± 0.513
2.151CysLys: 2.151 ± 0.672
2.582CysLeu: 2.582 ± 1.154
0.0CysMet: 0.0 ± 0.0
0.861CysAsn: 0.861 ± 0.51
1.291CysPro: 1.291 ± 0.654
0.43CysGln: 0.43 ± 0.341
0.861CysArg: 0.861 ± 0.688
2.582CysSer: 2.582 ± 0.93
1.291CysThr: 1.291 ± 0.629
0.0CysVal: 0.0 ± 0.0
0.43CysTrp: 0.43 ± 0.344
0.861CysTyr: 0.861 ± 0.401
0.0CysXaa: 0.0 ± 0.0
Asp
3.012AspAla: 3.012 ± 0.821
1.291AspCys: 1.291 ± 0.446
3.873AspAsp: 3.873 ± 0.99
6.885AspGlu: 6.885 ± 2.999
2.151AspPhe: 2.151 ± 0.69
0.861AspGly: 0.861 ± 0.684
0.861AspHis: 0.861 ± 0.392
4.303AspIle: 4.303 ± 1.242
6.024AspLys: 6.024 ± 2.757
6.024AspLeu: 6.024 ± 1.532
0.0AspMet: 0.0 ± 0.0
5.164AspAsn: 5.164 ± 2.139
1.291AspPro: 1.291 ± 0.649
2.582AspGln: 2.582 ± 1.092
2.151AspArg: 2.151 ± 1.286
3.442AspSer: 3.442 ± 1.183
3.442AspThr: 3.442 ± 0.709
2.151AspVal: 2.151 ± 0.98
0.861AspTrp: 0.861 ± 0.684
2.151AspTyr: 2.151 ± 1.022
0.0AspXaa: 0.0 ± 0.0
Glu
4.303GluAla: 4.303 ± 1.094
1.291GluCys: 1.291 ± 0.825
3.873GluAsp: 3.873 ± 0.703
8.176GluGlu: 8.176 ± 1.372
2.151GluPhe: 2.151 ± 0.672
3.012GluGly: 3.012 ± 0.565
2.582GluHis: 2.582 ± 0.925
9.466GluIle: 9.466 ± 1.491
8.606GluLys: 8.606 ± 1.356
5.164GluLeu: 5.164 ± 1.166
1.721GluMet: 1.721 ± 0.817
2.582GluAsn: 2.582 ± 1.176
3.442GluPro: 3.442 ± 1.192
3.873GluGln: 3.873 ± 0.748
4.303GluArg: 4.303 ± 1.034
4.303GluSer: 4.303 ± 1.253
3.012GluThr: 3.012 ± 0.629
3.442GluVal: 3.442 ± 0.785
0.43GluTrp: 0.43 ± 0.409
0.43GluTyr: 0.43 ± 0.344
0.0GluXaa: 0.0 ± 0.0
Phe
1.291PheAla: 1.291 ± 0.622
1.291PheCys: 1.291 ± 0.446
1.721PheAsp: 1.721 ± 0.744
2.151PheGlu: 2.151 ± 0.681
0.861PhePhe: 0.861 ± 0.51
2.151PheGly: 2.151 ± 0.787
0.861PheHis: 0.861 ± 0.392
3.012PheIle: 3.012 ± 0.635
4.303PheLys: 4.303 ± 1.242
3.442PheLeu: 3.442 ± 1.455
0.43PheMet: 0.43 ± 0.409
0.861PheAsn: 0.861 ± 0.684
1.721PhePro: 1.721 ± 0.579
3.012PheGln: 3.012 ± 1.083
2.151PheArg: 2.151 ± 1.029
2.151PheSer: 2.151 ± 0.609
4.303PheThr: 4.303 ± 1.214
0.43PheVal: 0.43 ± 0.341
0.861PheTrp: 0.861 ± 0.682
1.291PheTyr: 1.291 ± 0.662
0.0PheXaa: 0.0 ± 0.0
Gly
2.582GlyAla: 2.582 ± 0.903
0.43GlyCys: 0.43 ± 0.344
2.582GlyAsp: 2.582 ± 0.636
1.721GlyGlu: 1.721 ± 0.61
2.151GlyPhe: 2.151 ± 1.064
2.151GlyGly: 2.151 ± 0.582
0.861GlyHis: 0.861 ± 0.392
2.582GlyIle: 2.582 ± 0.729
3.873GlyLys: 3.873 ± 0.387
5.594GlyLeu: 5.594 ± 1.499
0.43GlyMet: 0.43 ± 0.416
3.873GlyAsn: 3.873 ± 1.678
1.291GlyPro: 1.291 ± 0.629
2.151GlyGln: 2.151 ± 0.533
0.43GlyArg: 0.43 ± 0.342
2.151GlySer: 2.151 ± 1.129
3.873GlyThr: 3.873 ± 0.702
1.291GlyVal: 1.291 ± 0.622
0.43GlyTrp: 0.43 ± 0.341
1.291GlyTyr: 1.291 ± 0.622
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.861HisCys: 0.861 ± 0.585
1.721HisAsp: 1.721 ± 1.07
0.43HisGlu: 0.43 ± 0.342
1.721HisPhe: 1.721 ± 0.689
0.861HisGly: 0.861 ± 0.412
0.43HisHis: 0.43 ± 0.409
0.861HisIle: 0.861 ± 0.585
0.861HisLys: 0.861 ± 0.392
1.291HisLeu: 1.291 ± 0.676
1.291HisMet: 1.291 ± 0.704
1.291HisAsn: 1.291 ± 0.362
0.43HisPro: 0.43 ± 0.344
1.721HisGln: 1.721 ± 0.666
0.0HisArg: 0.0 ± 0.0
2.151HisSer: 2.151 ± 0.653
0.43HisThr: 0.43 ± 0.341
0.861HisVal: 0.861 ± 0.682
0.0HisTrp: 0.0 ± 0.0
1.291HisTyr: 1.291 ± 0.362
0.0HisXaa: 0.0 ± 0.0
Ile
3.012IleAla: 3.012 ± 0.629
1.721IleCys: 1.721 ± 0.689
4.733IleAsp: 4.733 ± 1.673
2.582IleGlu: 2.582 ± 0.437
2.582IlePhe: 2.582 ± 1.014
3.873IleGly: 3.873 ± 0.974
1.721IleHis: 1.721 ± 1.322
6.454IleIle: 6.454 ± 1.5
8.606IleLys: 8.606 ± 2.146
5.594IleLeu: 5.594 ± 1.608
1.291IleMet: 1.291 ± 0.384
6.454IleAsn: 6.454 ± 1.075
3.873IlePro: 3.873 ± 1.42
2.582IleGln: 2.582 ± 0.89
1.291IleArg: 1.291 ± 0.544
6.454IleSer: 6.454 ± 1.585
4.303IleThr: 4.303 ± 1.342
3.442IleVal: 3.442 ± 0.778
0.861IleTrp: 0.861 ± 0.399
4.733IleTyr: 4.733 ± 0.994
0.0IleXaa: 0.0 ± 0.0
Lys
7.745LysAla: 7.745 ± 1.406
1.291LysCys: 1.291 ± 0.629
6.885LysAsp: 6.885 ± 2.075
7.315LysGlu: 7.315 ± 1.869
3.442LysPhe: 3.442 ± 0.997
5.594LysGly: 5.594 ± 0.821
1.721LysHis: 1.721 ± 0.587
7.745LysIle: 7.745 ± 1.84
15.06LysLys: 15.06 ± 2.714
7.745LysLeu: 7.745 ± 2.32
0.861LysMet: 0.861 ± 0.75
3.442LysAsn: 3.442 ± 0.719
6.024LysPro: 6.024 ± 1.288
5.594LysGln: 5.594 ± 2.553
3.873LysArg: 3.873 ± 1.241
8.176LysSer: 8.176 ± 2.191
4.303LysThr: 4.303 ± 1.034
4.733LysVal: 4.733 ± 1.89
1.721LysTrp: 1.721 ± 0.772
2.582LysTyr: 2.582 ± 1.354
0.0LysXaa: 0.0 ± 0.0
Leu
3.012LeuAla: 3.012 ± 1.087
3.012LeuCys: 3.012 ± 0.77
3.873LeuAsp: 3.873 ± 2.079
6.885LeuGlu: 6.885 ± 1.192
2.151LeuPhe: 2.151 ± 0.854
4.303LeuGly: 4.303 ± 1.389
0.861LeuHis: 0.861 ± 0.682
5.594LeuIle: 5.594 ± 1.44
9.897LeuLys: 9.897 ± 3.102
8.176LeuLeu: 8.176 ± 0.871
0.861LeuMet: 0.861 ± 0.468
2.151LeuAsn: 2.151 ± 0.612
3.873LeuPro: 3.873 ± 1.135
4.733LeuGln: 4.733 ± 0.994
6.024LeuArg: 6.024 ± 0.993
7.315LeuSer: 7.315 ± 1.462
5.594LeuThr: 5.594 ± 0.883
3.873LeuVal: 3.873 ± 1.141
0.861LeuTrp: 0.861 ± 0.392
3.012LeuTyr: 3.012 ± 0.895
0.0LeuXaa: 0.0 ± 0.0
Met
1.721MetAla: 1.721 ± 0.334
0.0MetCys: 0.0 ± 0.0
1.291MetAsp: 1.291 ± 0.918
1.291MetGlu: 1.291 ± 0.386
1.291MetPhe: 1.291 ± 0.697
0.861MetGly: 0.861 ± 0.646
0.43MetHis: 0.43 ± 0.503
0.43MetIle: 0.43 ± 0.409
1.721MetLys: 1.721 ± 0.585
0.861MetLeu: 0.861 ± 0.412
0.43MetMet: 0.43 ± 0.341
1.291MetAsn: 1.291 ± 0.696
0.0MetPro: 0.0 ± 0.0
0.861MetGln: 0.861 ± 0.682
0.43MetArg: 0.43 ± 0.341
3.012MetSer: 3.012 ± 1.185
1.291MetThr: 1.291 ± 0.551
1.721MetVal: 1.721 ± 0.774
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.012AsnAla: 3.012 ± 0.711
0.43AsnCys: 0.43 ± 0.342
1.291AsnAsp: 1.291 ± 0.662
3.012AsnGlu: 3.012 ± 0.635
3.873AsnPhe: 3.873 ± 1.3
3.442AsnGly: 3.442 ± 1.898
1.291AsnHis: 1.291 ± 0.674
4.303AsnIle: 4.303 ± 1.961
3.012AsnLys: 3.012 ± 1.448
5.594AsnLeu: 5.594 ± 1.393
1.291AsnMet: 1.291 ± 0.561
3.442AsnAsn: 3.442 ± 1.185
5.164AsnPro: 5.164 ± 1.209
2.582AsnGln: 2.582 ± 0.702
2.151AsnArg: 2.151 ± 0.361
4.303AsnSer: 4.303 ± 1.2
3.012AsnThr: 3.012 ± 1.195
2.151AsnVal: 2.151 ± 1.152
0.861AsnTrp: 0.861 ± 0.635
1.721AsnTyr: 1.721 ± 0.579
0.0AsnXaa: 0.0 ± 0.0
Pro
1.291ProAla: 1.291 ± 0.676
0.43ProCys: 0.43 ± 0.593
4.303ProAsp: 4.303 ± 1.542
3.442ProGlu: 3.442 ± 1.107
1.721ProPhe: 1.721 ± 0.744
1.291ProGly: 1.291 ± 0.362
0.43ProHis: 0.43 ± 0.496
3.442ProIle: 3.442 ± 0.748
6.885ProLys: 6.885 ± 1.309
2.151ProLeu: 2.151 ± 0.665
0.43ProMet: 0.43 ± 0.341
1.721ProAsn: 1.721 ± 0.66
1.291ProPro: 1.291 ± 0.856
3.012ProGln: 3.012 ± 1.182
2.151ProArg: 2.151 ± 0.557
4.303ProSer: 4.303 ± 1.076
3.442ProThr: 3.442 ± 0.603
2.582ProVal: 2.582 ± 0.887
0.0ProTrp: 0.0 ± 0.0
0.861ProTyr: 0.861 ± 0.717
0.0ProXaa: 0.0 ± 0.0
Gln
2.151GlnAla: 2.151 ± 0.594
0.861GlnCys: 0.861 ± 0.412
2.582GlnAsp: 2.582 ± 0.909
11.188GlnGlu: 11.188 ± 1.711
1.291GlnPhe: 1.291 ± 0.912
1.291GlnGly: 1.291 ± 0.362
0.861GlnHis: 0.861 ± 0.401
3.873GlnIle: 3.873 ± 1.631
3.442GlnLys: 3.442 ± 0.785
5.164GlnLeu: 5.164 ± 0.894
1.291GlnMet: 1.291 ± 0.386
3.012GlnAsn: 3.012 ± 0.647
2.151GlnPro: 2.151 ± 0.593
3.442GlnGln: 3.442 ± 1.403
3.012GlnArg: 3.012 ± 0.861
1.721GlnSer: 1.721 ± 0.68
2.151GlnThr: 2.151 ± 0.672
2.582GlnVal: 2.582 ± 0.925
0.861GlnTrp: 0.861 ± 0.682
0.861GlnTyr: 0.861 ± 0.51
0.0GlnXaa: 0.0 ± 0.0
Arg
0.43ArgAla: 0.43 ± 0.344
0.861ArgCys: 0.861 ± 0.688
1.291ArgAsp: 1.291 ± 0.362
0.861ArgGlu: 0.861 ± 0.657
2.582ArgPhe: 2.582 ± 0.799
1.721ArgGly: 1.721 ± 1.364
1.721ArgHis: 1.721 ± 0.573
3.873ArgIle: 3.873 ± 1.065
6.454ArgLys: 6.454 ± 1.501
3.873ArgLeu: 3.873 ± 1.301
0.861ArgMet: 0.861 ± 0.596
2.151ArgAsn: 2.151 ± 1.319
1.721ArgPro: 1.721 ± 0.688
2.151ArgGln: 2.151 ± 0.361
1.721ArgArg: 1.721 ± 0.558
1.291ArgSer: 1.291 ± 0.711
1.721ArgThr: 1.721 ± 0.579
2.582ArgVal: 2.582 ± 0.828
0.43ArgTrp: 0.43 ± 0.344
1.291ArgTyr: 1.291 ± 0.551
0.0ArgXaa: 0.0 ± 0.0
Ser
1.291SerAla: 1.291 ± 0.766
0.0SerCys: 0.0 ± 0.0
5.164SerAsp: 5.164 ± 1.097
6.454SerGlu: 6.454 ± 1.263
3.442SerPhe: 3.442 ± 0.683
3.442SerGly: 3.442 ± 0.818
1.291SerHis: 1.291 ± 0.676
7.315SerIle: 7.315 ± 1.775
7.745SerLys: 7.745 ± 1.19
7.315SerLeu: 7.315 ± 1.418
0.861SerMet: 0.861 ± 0.566
6.024SerAsn: 6.024 ± 1.502
3.012SerPro: 3.012 ± 1.156
3.873SerGln: 3.873 ± 1.386
3.012SerArg: 3.012 ± 0.782
7.745SerSer: 7.745 ± 2.473
3.873SerThr: 3.873 ± 1.201
3.012SerVal: 3.012 ± 0.587
0.861SerTrp: 0.861 ± 0.585
3.012SerTyr: 3.012 ± 0.923
0.0SerXaa: 0.0 ± 0.0
Thr
3.012ThrAla: 3.012 ± 0.645
1.291ThrCys: 1.291 ± 0.654
3.012ThrAsp: 3.012 ± 0.636
4.733ThrGlu: 4.733 ± 1.889
1.291ThrPhe: 1.291 ± 0.662
1.721ThrGly: 1.721 ± 0.66
0.43ThrHis: 0.43 ± 0.341
4.733ThrIle: 4.733 ± 0.727
3.873ThrLys: 3.873 ± 1.143
2.582ThrLeu: 2.582 ± 0.462
1.721ThrMet: 1.721 ± 0.488
3.873ThrAsn: 3.873 ± 1.075
2.582ThrPro: 2.582 ± 0.819
3.442ThrGln: 3.442 ± 0.997
2.151ThrArg: 2.151 ± 0.856
4.733ThrSer: 4.733 ± 1.678
2.151ThrThr: 2.151 ± 0.593
4.303ThrVal: 4.303 ± 1.104
0.43ThrTrp: 0.43 ± 0.409
1.721ThrTyr: 1.721 ± 0.334
0.0ThrXaa: 0.0 ± 0.0
Val
1.721ValAla: 1.721 ± 0.521
0.861ValCys: 0.861 ± 0.682
3.873ValAsp: 3.873 ± 0.979
2.151ValGlu: 2.151 ± 0.672
2.582ValPhe: 2.582 ± 0.526
2.151ValGly: 2.151 ± 1.045
0.861ValHis: 0.861 ± 0.535
2.582ValIle: 2.582 ± 1.349
6.024ValLys: 6.024 ± 1.134
3.873ValLeu: 3.873 ± 1.207
1.721ValMet: 1.721 ± 0.801
1.291ValAsn: 1.291 ± 0.561
1.291ValPro: 1.291 ± 0.674
3.012ValGln: 3.012 ± 0.77
2.151ValArg: 2.151 ± 0.582
3.873ValSer: 3.873 ± 1.237
1.721ValThr: 1.721 ± 0.724
2.582ValVal: 2.582 ± 1.257
0.43ValTrp: 0.43 ± 0.341
2.151ValTyr: 2.151 ± 0.776
0.0ValXaa: 0.0 ± 0.0
Trp
0.43TrpAla: 0.43 ± 0.342
0.0TrpCys: 0.0 ± 0.0
0.43TrpAsp: 0.43 ± 0.344
1.291TrpGlu: 1.291 ± 0.362
0.0TrpPhe: 0.0 ± 0.0
0.43TrpGly: 0.43 ± 0.341
0.0TrpHis: 0.0 ± 0.0
0.861TrpIle: 0.861 ± 0.688
0.43TrpLys: 0.43 ± 0.342
0.861TrpLeu: 0.861 ± 0.51
0.43TrpMet: 0.43 ± 0.341
1.721TrpAsn: 1.721 ± 0.729
0.43TrpPro: 0.43 ± 0.603
0.43TrpGln: 0.43 ± 0.341
0.43TrpArg: 0.43 ± 0.341
1.291TrpSer: 1.291 ± 0.622
0.0TrpThr: 0.0 ± 0.0
0.861TrpVal: 0.861 ± 0.392
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.291TyrAla: 1.291 ± 0.446
1.721TyrCys: 1.721 ± 0.689
1.721TyrAsp: 1.721 ± 0.334
2.151TyrGlu: 2.151 ± 0.681
0.861TyrPhe: 0.861 ± 0.51
0.861TyrGly: 0.861 ± 0.468
0.43TyrHis: 0.43 ± 0.342
1.291TyrIle: 1.291 ± 1.023
3.442TyrLys: 3.442 ± 1.177
3.442TyrLeu: 3.442 ± 1.366
0.43TyrMet: 0.43 ± 0.33
1.291TyrAsn: 1.291 ± 0.362
3.012TyrPro: 3.012 ± 1.087
2.151TyrGln: 2.151 ± 0.686
0.0TyrArg: 0.0 ± 0.0
2.582TyrSer: 2.582 ± 1.107
1.721TyrThr: 1.721 ± 0.768
3.012TyrVal: 3.012 ± 0.643
0.0TyrTrp: 0.0 ± 0.0
0.43TyrTyr: 0.43 ± 0.496
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (2325 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski