Amino acid dipepetide frequency for Arachis duranensis (Wild peanut)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.979AlaAla: 5.979 ± 0.027	1.206AlaCys: 1.206 ± 0.01	3.019AlaAsp: 3.019 ± 0.014	4.081AlaGlu: 4.081 ± 0.018	2.69AlaPhe: 2.69 ± 0.014	3.729AlaGly: 3.729 ± 0.019	1.272AlaHis: 1.272 ± 0.008	3.817AlaIle: 3.817 ± 0.017	3.939AlaLys: 3.939 ± 0.017	6.35AlaLeu: 6.35 ± 0.023	1.739AlaMet: 1.739 ± 0.01	2.658AlaAsn: 2.658 ± 0.012	2.732AlaPro: 2.732 ± 0.015	2.054AlaGln: 2.054 ± 0.012	3.252AlaArg: 3.252 ± 0.014	5.805AlaSer: 5.805 ± 0.019	3.641AlaThr: 3.641 ± 0.018	4.496AlaVal: 4.496 ± 0.018	0.761AlaTrp: 0.761 ± 0.006	1.836AlaTyr: 1.836 ± 0.01	0.003AlaXaa: 0.003 ± 0.0
Cys	0.992CysAla: 0.992 ± 0.007	0.565CysCys: 0.565 ± 0.006	0.965CysAsp: 0.965 ± 0.007	0.928CysGlu: 0.928 ± 0.007	0.948CysPhe: 0.948 ± 0.008	1.368CysGly: 1.368 ± 0.01	0.545CysHis: 0.545 ± 0.006	1.099CysIle: 1.099 ± 0.007	1.225CysLys: 1.225 ± 0.011	1.914CysLeu: 1.914 ± 0.012	0.502CysMet: 0.502 ± 0.006	0.922CysAsn: 0.922 ± 0.007	0.916CysPro: 0.916 ± 0.007	0.637CysGln: 0.637 ± 0.006	1.066CysArg: 1.066 ± 0.009	1.858CysSer: 1.858 ± 0.012	0.88CysThr: 0.88 ± 0.006	1.133CysVal: 1.133 ± 0.009	0.264CysTrp: 0.264 ± 0.004	0.594CysTyr: 0.594 ± 0.006	0.002CysXaa: 0.002 ± 0.0
Asp	3.573AspAla: 3.573 ± 0.015	0.97AspCys: 0.97 ± 0.007	3.92AspAsp: 3.92 ± 0.021	4.107AspGlu: 4.107 ± 0.02	2.298AspPhe: 2.298 ± 0.012	3.665AspGly: 3.665 ± 0.017	1.298AspHis: 1.298 ± 0.009	3.143AspIle: 3.143 ± 0.014	2.851AspLys: 2.851 ± 0.013	5.062AspLeu: 5.062 ± 0.018	1.364AspMet: 1.364 ± 0.009	2.291AspAsn: 2.291 ± 0.011	2.561AspPro: 2.561 ± 0.012	1.708AspGln: 1.708 ± 0.01	2.309AspArg: 2.309 ± 0.012	4.24AspSer: 4.24 ± 0.02	2.249AspThr: 2.249 ± 0.012	3.532AspVal: 3.532 ± 0.015	0.728AspTrp: 0.728 ± 0.007	1.651AspTyr: 1.651 ± 0.009	0.003AspXaa: 0.003 ± 0.0
Glu	4.812GluAla: 4.812 ± 0.02	1.029GluCys: 1.029 ± 0.008	3.993GluAsp: 3.993 ± 0.017	6.311GluGlu: 6.311 ± 0.034	2.472GluPhe: 2.472 ± 0.012	3.736GluGly: 3.736 ± 0.016	1.35GluHis: 1.35 ± 0.009	3.716GluIle: 3.716 ± 0.016	4.737GluLys: 4.737 ± 0.02	5.974GluLeu: 5.974 ± 0.022	1.698GluMet: 1.698 ± 0.009	3.199GluAsn: 3.199 ± 0.017	2.117GluPro: 2.117 ± 0.011	2.23GluGln: 2.23 ± 0.013	3.326GluArg: 3.326 ± 0.016	4.548GluSer: 4.548 ± 0.019	2.943GluThr: 2.943 ± 0.013	4.181GluVal: 4.181 ± 0.015	0.753GluTrp: 0.753 ± 0.007	1.706GluTyr: 1.706 ± 0.011	0.003GluXaa: 0.003 ± 0.0
Phe	2.457PheAla: 2.457 ± 0.011	0.941PheCys: 0.941 ± 0.007	2.354PheAsp: 2.354 ± 0.013	2.345PheGlu: 2.345 ± 0.011	1.987PhePhe: 1.987 ± 0.014	2.98PheGly: 2.98 ± 0.019	1.194PheHis: 1.194 ± 0.008	2.127PheIle: 2.127 ± 0.012	2.22PheLys: 2.22 ± 0.012	4.308PheLeu: 4.308 ± 0.017	0.975PheMet: 0.975 ± 0.008	1.811PheAsn: 1.811 ± 0.011	2.162PhePro: 2.162 ± 0.012	1.652PheGln: 1.652 ± 0.011	2.104PheArg: 2.104 ± 0.011	3.963PheSer: 3.963 ± 0.014	2.019PheThr: 2.019 ± 0.01	2.731PheVal: 2.731 ± 0.014	0.6PheTrp: 0.6 ± 0.006	1.303PheTyr: 1.303 ± 0.009	0.003PheXaa: 0.003 ± 0.0
Gly	3.642GlyAla: 3.642 ± 0.018	1.332GlyCys: 1.332 ± 0.01	3.322GlyAsp: 3.322 ± 0.014	3.506GlyGlu: 3.506 ± 0.013	2.918GlyPhe: 2.918 ± 0.015	5.022GlyGly: 5.022 ± 0.034	1.53GlyHis: 1.53 ± 0.01	3.532GlyIle: 3.532 ± 0.016	3.947GlyLys: 3.947 ± 0.016	5.498GlyLeu: 5.498 ± 0.021	1.421GlyMet: 1.421 ± 0.009	3.05GlyAsn: 3.05 ± 0.016	2.217GlyPro: 2.217 ± 0.013	1.992GlyGln: 1.992 ± 0.01	3.389GlyArg: 3.389 ± 0.017	5.659GlySer: 5.659 ± 0.022	3.163GlyThr: 3.163 ± 0.014	4.004GlyVal: 4.004 ± 0.016	0.832GlyTrp: 0.832 ± 0.007	2.045GlyTyr: 2.045 ± 0.011	0.004GlyXaa: 0.004 ± 0.0
His	1.475HisAla: 1.475 ± 0.009	0.585HisCys: 0.585 ± 0.005	1.308HisAsp: 1.308 ± 0.008	1.386HisGlu: 1.386 ± 0.008	1.135HisPhe: 1.135 ± 0.008	1.748HisGly: 1.748 ± 0.012	1.256HisHis: 1.256 ± 0.014	1.326HisIle: 1.326 ± 0.009	1.286HisLys: 1.286 ± 0.009	2.569HisLeu: 2.569 ± 0.012	0.596HisMet: 0.596 ± 0.005	1.167HisAsn: 1.167 ± 0.008	1.377HisPro: 1.377 ± 0.009	1.145HisGln: 1.145 ± 0.009	1.481HisArg: 1.481 ± 0.009	2.061HisSer: 2.061 ± 0.012	1.074HisThr: 1.074 ± 0.007	1.672HisVal: 1.672 ± 0.009	0.326HisTrp: 0.326 ± 0.004	0.749HisTyr: 0.749 ± 0.007	0.002HisXaa: 0.002 ± 0.0
Ile	3.512IleAla: 3.512 ± 0.016	1.109IleCys: 1.109 ± 0.007	2.962IleAsp: 2.962 ± 0.014	3.307IleGlu: 3.307 ± 0.014	2.313IlePhe: 2.313 ± 0.013	3.344IleGly: 3.344 ± 0.014	1.437IleHis: 1.437 ± 0.009	3.062IleIle: 3.062 ± 0.017	3.154IleLys: 3.154 ± 0.014	5.405IleLeu: 5.405 ± 0.022	1.255IleMet: 1.255 ± 0.008	2.39IleAsn: 2.39 ± 0.011	3.01IlePro: 3.01 ± 0.018	2.124IleGln: 2.124 ± 0.011	2.741IleArg: 2.741 ± 0.014	4.78IleSer: 4.78 ± 0.018	2.661IleThr: 2.661 ± 0.014	3.502IleVal: 3.502 ± 0.016	0.735IleTrp: 0.735 ± 0.006	1.529IleTyr: 1.529 ± 0.01	0.003IleXaa: 0.003 ± 0.0
Lys	4.005LysAla: 4.005 ± 0.014	1.078LysCys: 1.078 ± 0.008	3.457LysAsp: 3.457 ± 0.014	4.835LysGlu: 4.835 ± 0.018	2.364LysPhe: 2.364 ± 0.013	3.654LysGly: 3.654 ± 0.016	1.475LysHis: 1.475 ± 0.01	3.365LysIle: 3.365 ± 0.012	4.958LysLys: 4.958 ± 0.028	6.156LysLeu: 6.156 ± 0.024	1.564LysMet: 1.564 ± 0.01	2.873LysAsn: 2.873 ± 0.014	2.684LysPro: 2.684 ± 0.015	2.385LysGln: 2.385 ± 0.012	3.63LysArg: 3.63 ± 0.016	4.637LysSer: 4.637 ± 0.017	2.877LysThr: 2.877 ± 0.013	3.994LysVal: 3.994 ± 0.014	0.827LysTrp: 0.827 ± 0.007	1.742LysTyr: 1.742 ± 0.009	0.003LysXaa: 0.003 ± 0.0
Leu	6.242LeuAla: 6.242 ± 0.02	1.983LeuCys: 1.983 ± 0.011	5.162LeuAsp: 5.162 ± 0.018	6.402LeuGlu: 6.402 ± 0.026	3.855LeuPhe: 3.855 ± 0.017	5.46LeuGly: 5.46 ± 0.021	2.732LeuHis: 2.732 ± 0.012	4.676LeuIle: 4.676 ± 0.02	6.389LeuLys: 6.389 ± 0.023	9.816LeuLeu: 9.816 ± 0.032	2.163LeuMet: 2.163 ± 0.012	4.113LeuAsn: 4.113 ± 0.017	5.179LeuPro: 5.179 ± 0.019	4.409LeuGln: 4.409 ± 0.017	5.468LeuArg: 5.468 ± 0.017	8.413LeuSer: 8.413 ± 0.03	4.404LeuThr: 4.404 ± 0.018	6.244LeuVal: 6.244 ± 0.02	1.152LeuTrp: 1.152 ± 0.008	2.596LeuTyr: 2.596 ± 0.013	0.005LeuXaa: 0.005 ± 0.001
Met	2.002MetAla: 2.002 ± 0.011	0.384MetCys: 0.384 ± 0.004	1.399MetAsp: 1.399 ± 0.009	1.977MetGlu: 1.977 ± 0.011	0.873MetPhe: 0.873 ± 0.007	1.462MetGly: 1.462 ± 0.009	0.621MetHis: 0.621 ± 0.006	1.248MetIle: 1.248 ± 0.009	1.734MetLys: 1.734 ± 0.01	2.28MetLeu: 2.28 ± 0.012	0.755MetMet: 0.755 ± 0.008	1.092MetAsn: 1.092 ± 0.007	1.115MetPro: 1.115 ± 0.009	0.983MetGln: 0.983 ± 0.008	1.28MetArg: 1.28 ± 0.009	1.769MetSer: 1.769 ± 0.01	1.081MetThr: 1.081 ± 0.007	1.652MetVal: 1.652 ± 0.009	0.271MetTrp: 0.271 ± 0.004	0.581MetTyr: 0.581 ± 0.005	0.001MetXaa: 0.001 ± 0.0
Asn	2.795AsnAla: 2.795 ± 0.012	0.913AsnCys: 0.913 ± 0.008	2.325AsnAsp: 2.325 ± 0.013	2.642AsnGlu: 2.642 ± 0.013	1.958AsnPhe: 1.958 ± 0.011	3.287AsnGly: 3.287 ± 0.018	1.286AsnHis: 1.286 ± 0.009	2.673AsnIle: 2.673 ± 0.013	2.782AsnLys: 2.782 ± 0.012	4.811AsnLeu: 4.811 ± 0.024	1.251AsnMet: 1.251 ± 0.009	3.258AsnAsn: 3.258 ± 0.027	2.334AsnPro: 2.334 ± 0.012	1.828AsnGln: 1.828 ± 0.011	2.074AsnArg: 2.074 ± 0.011	4.03AsnSer: 4.03 ± 0.016	2.113AsnThr: 2.113 ± 0.011	2.838AsnVal: 2.838 ± 0.014	0.601AsnTrp: 0.601 ± 0.006	1.393AsnTyr: 1.393 ± 0.01	0.002AsnXaa: 0.002 ± 0.0
Pro	2.75ProAla: 2.75 ± 0.016	0.821ProCys: 0.821 ± 0.008	2.296ProAsp: 2.296 ± 0.011	2.952ProGlu: 2.952 ± 0.014	2.044ProPhe: 2.044 ± 0.011	2.391ProGly: 2.391 ± 0.013	1.19ProHis: 1.19 ± 0.011	2.375ProIle: 2.375 ± 0.014	2.773ProLys: 2.773 ± 0.016	4.321ProLeu: 4.321 ± 0.016	0.978ProMet: 0.978 ± 0.008	2.449ProAsn: 2.449 ± 0.013	4.021ProPro: 4.021 ± 0.049	1.91ProGln: 1.91 ± 0.011	2.381ProArg: 2.381 ± 0.012	5.159ProSer: 5.159 ± 0.023	2.597ProThr: 2.597 ± 0.013	2.883ProVal: 2.883 ± 0.016	0.574ProTrp: 0.574 ± 0.005	1.361ProTyr: 1.361 ± 0.012	0.002ProXaa: 0.002 ± 0.0
Gln	2.29GlnAla: 2.29 ± 0.012	0.606GlnCys: 0.606 ± 0.006	1.788GlnAsp: 1.788 ± 0.01	2.564GlnGlu: 2.564 ± 0.014	1.457GlnPhe: 1.457 ± 0.008	2.139GlnGly: 2.139 ± 0.013	1.104GlnHis: 1.104 ± 0.007	2.071GlnIle: 2.071 ± 0.012	2.439GlnLys: 2.439 ± 0.014	3.723GlnLeu: 3.723 ± 0.016	0.982GlnMet: 0.982 ± 0.009	1.897GlnAsn: 1.897 ± 0.011	1.833GlnPro: 1.833 ± 0.011	2.235GlnGln: 2.235 ± 0.025	2.153GlnArg: 2.153 ± 0.01	2.813GlnSer: 2.813 ± 0.014	1.699GlnThr: 1.699 ± 0.009	2.429GlnVal: 2.429 ± 0.012	0.466GlnTrp: 0.466 ± 0.005	0.995GlnTyr: 0.995 ± 0.007	0.002GlnXaa: 0.002 ± 0.0
Arg	3.073ArgAla: 3.073 ± 0.013	1.063ArgCys: 1.063 ± 0.009	2.647ArgAsp: 2.647 ± 0.013	3.342ArgGlu: 3.342 ± 0.015	2.272ArgPhe: 2.272 ± 0.011	3.078ArgGly: 3.078 ± 0.017	1.378ArgHis: 1.378 ± 0.01	2.967ArgIle: 2.967 ± 0.012	3.831ArgLys: 3.831 ± 0.016	4.883ArgLeu: 4.883 ± 0.019	1.38ArgMet: 1.38 ± 0.009	2.524ArgAsn: 2.524 ± 0.011	2.237ArgPro: 2.237 ± 0.012	1.89ArgGln: 1.89 ± 0.013	3.909ArgArg: 3.909 ± 0.022	4.218ArgSer: 4.218 ± 0.019	2.436ArgThr: 2.436 ± 0.01	3.296ArgVal: 3.296 ± 0.013	0.822ArgTrp: 0.822 ± 0.007	1.54ArgTyr: 1.54 ± 0.009	0.003ArgXaa: 0.003 ± 0.0
Ser	5.049SerAla: 5.049 ± 0.021	1.7SerCys: 1.7 ± 0.011	4.414SerAsp: 4.414 ± 0.019	4.677SerGlu: 4.677 ± 0.019	3.98SerPhe: 3.98 ± 0.015	5.382SerGly: 5.382 ± 0.022	2.151SerHis: 2.151 ± 0.011	4.629SerIle: 4.629 ± 0.016	5.003SerLys: 5.003 ± 0.018	8.585SerLeu: 8.585 ± 0.025	2.091SerMet: 2.091 ± 0.01	4.317SerAsn: 4.317 ± 0.017	4.286SerPro: 4.286 ± 0.026	3.098SerGln: 3.098 ± 0.014	4.364SerArg: 4.364 ± 0.016	11.119SerSer: 11.119 ± 0.038	4.546SerThr: 4.546 ± 0.015	5.067SerVal: 5.067 ± 0.019	1.183SerTrp: 1.183 ± 0.009	2.383SerTyr: 2.383 ± 0.011	0.005SerXaa: 0.005 ± 0.0
Thr	3.219ThrAla: 3.219 ± 0.015	0.967ThrCys: 0.967 ± 0.007	2.208ThrAsp: 2.208 ± 0.011	2.683ThrGlu: 2.683 ± 0.012	2.078ThrPhe: 2.078 ± 0.01	2.869ThrGly: 2.869 ± 0.015	1.166ThrHis: 1.166 ± 0.009	2.877ThrIle: 2.877 ± 0.013	2.803ThrLys: 2.803 ± 0.011	4.848ThrLeu: 4.848 ± 0.018	1.226ThrMet: 1.226 ± 0.008	2.269ThrAsn: 2.269 ± 0.013	2.57ThrPro: 2.57 ± 0.014	1.655ThrGln: 1.655 ± 0.009	2.459ThrArg: 2.459 ± 0.012	4.461ThrSer: 4.461 ± 0.017	3.272ThrThr: 3.272 ± 0.017	3.168ThrVal: 3.168 ± 0.013	0.65ThrTrp: 0.65 ± 0.006	1.435ThrTyr: 1.435 ± 0.013	0.003ThrXaa: 0.003 ± 0.0
Val	4.707ValAla: 4.707 ± 0.018	1.136ValCys: 1.136 ± 0.009	3.72ValAsp: 3.72 ± 0.016	4.354ValGlu: 4.354 ± 0.016	2.657ValPhe: 2.657 ± 0.015	3.929ValGly: 3.929 ± 0.015	1.585ValHis: 1.585 ± 0.01	3.421ValIle: 3.421 ± 0.015	3.901ValLys: 3.901 ± 0.015	6.228ValLeu: 6.228 ± 0.022	1.519ValMet: 1.519 ± 0.01	2.692ValAsn: 2.692 ± 0.012	3.127ValPro: 3.127 ± 0.014	2.295ValGln: 2.295 ± 0.011	3.012ValArg: 3.012 ± 0.013	5.179ValSer: 5.179 ± 0.019	3.253ValThr: 3.253 ± 0.014	4.86ValVal: 4.86 ± 0.018	0.77ValTrp: 0.77 ± 0.007	1.921ValTyr: 1.921 ± 0.01	0.005ValXaa: 0.005 ± 0.0
Trp	0.706TrpAla: 0.706 ± 0.007	0.267TrpCys: 0.267 ± 0.004	0.679TrpAsp: 0.679 ± 0.006	0.804TrpGlu: 0.804 ± 0.007	0.604TrpPhe: 0.604 ± 0.006	0.674TrpGly: 0.674 ± 0.007	0.351TrpHis: 0.351 ± 0.004	0.704TrpIle: 0.704 ± 0.006	0.994TrpLys: 0.994 ± 0.009	1.296TrpLeu: 1.296 ± 0.009	0.362TrpMet: 0.362 ± 0.004	0.748TrpAsn: 0.748 ± 0.006	0.483TrpPro: 0.483 ± 0.006	0.453TrpGln: 0.453 ± 0.005	0.826TrpArg: 0.826 ± 0.007	1.01TrpSer: 1.01 ± 0.008	0.641TrpThr: 0.641 ± 0.005	0.78TrpVal: 0.78 ± 0.006	0.252TrpTrp: 0.252 ± 0.004	0.345TrpTyr: 0.345 ± 0.005	0.001TrpXaa: 0.001 ± 0.0
Tyr	1.775TyrAla: 1.775 ± 0.01	0.668TyrCys: 0.668 ± 0.006	1.586TyrAsp: 1.586 ± 0.01	1.626TyrGlu: 1.626 ± 0.011	1.324TyrPhe: 1.324 ± 0.009	2.105TyrGly: 2.105 ± 0.012	0.801TyrHis: 0.801 ± 0.007	1.504TyrIle: 1.504 ± 0.01	1.594TyrLys: 1.594 ± 0.009	2.829TyrLeu: 2.829 ± 0.013	0.737TyrMet: 0.737 ± 0.006	1.472TyrAsn: 1.472 ± 0.01	1.263TyrPro: 1.263 ± 0.008	1.002TyrGln: 1.002 ± 0.008	1.561TyrArg: 1.561 ± 0.011	2.303TyrSer: 2.303 ± 0.012	1.334TyrThr: 1.334 ± 0.009	1.806TyrVal: 1.806 ± 0.01	0.414TyrTrp: 0.414 ± 0.005	1.043TyrTyr: 1.043 ± 0.011	0.002TyrXaa: 0.002 ± 0.0
Xaa	0.003XaaAla: 0.003 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.002XaaAsp: 0.002 ± 0.0	0.003XaaGlu: 0.003 ± 0.0	0.005XaaPhe: 0.005 ± 0.001	0.003XaaGly: 0.003 ± 0.0	0.002XaaHis: 0.002 ± 0.0	0.003XaaIle: 0.003 ± 0.0	0.003XaaLys: 0.003 ± 0.0	0.006XaaLeu: 0.006 ± 0.001	0.002XaaMet: 0.002 ± 0.0	0.003XaaAsn: 0.003 ± 0.0	0.003XaaPro: 0.003 ± 0.0	0.002XaaGln: 0.002 ± 0.0	0.004XaaArg: 0.004 ± 0.0	0.005XaaSer: 0.005 ± 0.0	0.002XaaThr: 0.002 ± 0.0	0.004XaaVal: 0.004 ± 0.0	0.001XaaTrp: 0.001 ± 0.0	0.002XaaTyr: 0.002 ± 0.0	0.07XaaXaa: 0.07 ± 0.009

Statistics based on 44786 proteins (19145231 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---